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Am J Gastroenterol 2022 Jun;117(6):1018

Am J Gastroenterol 2022 Jun;117(6):1016-1017

Division of Digestive Diseases and Nutrition, Joy McCann Culverhouse Center for Swallowing Disorders, University of South Florida Morsani College of Medicine, Tampa, Florida, USA.

Am J Gastroenterol 2022 Jun;117(6):1014-1015

Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.

Am J Gastroenterol 2022 Jun;117(6):1012

Section of Epidemiology and Population Sciences, Department of Medicine, Baylor College of Medicine, Houston, Texas, USA.

Am J Gastroenterol 2022 Jun;117(6):1010

Department of Gastrointestinal Surgery & Gastric Cancer Laboratory, West China Hospital, Sichuan University, Chengdu, China.

Am J Gastroenterol 2022 Jun 26;117(6):845. Epub 2022 Apr 26.

Carl T. Hayden VA Medical Center, Phoenix, Arizona.

Article Title: Green Tea Extract to Prevent Colorectal Adenomas, Results of a Randomized, Placebo-Controlled Clinical Trial. Read More

Am J Gastroenterol 2022 Jun 17;117(6):844. Epub 2022 Feb 17.

Massachusetts General Hospital, Boston, Massachusetts.

Article Title: Diagnosis and Management of Cancer Risk in the Gastrointestinal Hamartomatous Polyposis Syndromes: Recommendations From the US Multi-Society Task Force on Colorectal Cancer. Read More

Am J Gastroenterol 2022 Jun 1. Epub 2022 Jun 1.

(Associate Professor of Medicine and Surgery, Northwestern University, Department of Medicine, Division of Gastroenterology/Hepatology, Chicago, IL)

Am J Gastroenterol 2022 May 25. Epub 2022 May 25.

Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, Osaka, Japan.

Am J Gastroenterol 2022 May 25. Epub 2022 May 25.

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Solna, Sweden.

Objectives: To determine the risk of inflammatory bowel disease (IBD) in patients with celiac disease (CeD) (and vice versa) compared to general-population comparators.

Methods: Using Swedish histopathology and healthcare register data, we identified 48,551 patients with CeD and 83,529 with IBD diagnosed in 1969-2016. Each patient was compared to age- and sex-matched general-population comparators (CeD: n=240,136; IBD: n=408,195). Read More

Am J Gastroenterol 2022 May 25. Epub 2022 May 25.

Department of Internal Medicine, College of Medicine, Ewha Womans University, Seoul, Republic of Korea.

Introduction: A family history of gastric cancer (GC) is a well-known risk factor for GC. However, the association between family history of GC and the risk of GC and gastric adenoma according to the affected family members is unclear.

Methods: We analyzed the data of participants aged ≥40 years who underwent national GC screening between 2013 and 2014. Read More

Am J Gastroenterol 2022 May 18. Epub 2022 May 18.

Am J Gastroenterol 2022 May 18. Epub 2022 May 18.

. Karsh Division of Gastroenterology and Hepatology, Cedars-Sinai Medical Center, Los Angeles, California, United States.

Background Aims: Fundic Gland Polyps (FGPs) are commonly found in familial adenomatous polyposis (FAP) patients and are considered benign. Biopsies are not routinely done, and conventional forceps may be time-consuming and/or yield non-representative histology. The purpose of this study was to evaluate the role of a novel endoscopic polypectomy surveillance (EPS), a large volume cold-snare polypectomy technique of random FGPs, on the incidence of dysplasia and gastric cancer (GC) in FAP. Read More

Am J Gastroenterol 2022 May 12. Epub 2022 May 12.

Department of Internal Medicine, Pathum Thani Hospital, Pathum Thani, Thailand.

Am J Gastroenterol 2022 May 12. Epub 2022 May 12.

Division of Gastroenterology and Hepatology, Mayo Clinic Rochester, Rochester MN.

Abstract: When the only biologics were anti TNF agents, it was not hard to treat our sick Crohn's patients. Now with multiple mechanisms of action the therapeutic landscape is more broad but can be confusing. Trying to compare agents is difficult because head to head trials are lacking. Read More

Am J Gastroenterol 2022 May 12. Epub 2022 May 12.

Department of Gastroenterology, Ajou University School of Medicine, Suwon, Republic of Korea.

Am J Gastroenterol 2022 06 14;117(6):865-875. Epub 2022 Mar 14.

Center for Liver Diseases, Universty of Chicago Medicine, Chicago, Illinois, USA.

It has been over 50 years since the Stonewall Inn Riots in June 1969, a seminal event for the lesbian, gay, bisexual, transgender, queer, intersex, and other sexual and gender-diverse minorities (LGBTQI+, or lesbian, gay, bisexual, transgender, queer, intersex, and everyone else) rights movement. However, sexual and gender minority (SGM) individuals still face discrimination and harassment due to their sexual orientation or gender identity. As such, the National Institute on Minority Health and Health Disparities has identified SGM communities as a "health disparity population. Read More

Am J Gastroenterol 2022 May 9. Epub 2022 May 9.

Department of Gastroenterology.

Am J Gastroenterol 2022 May 9. Epub 2022 May 9.

Department of Gastroenterology, KIMS ICON Hospital, Visakhapatnam, India.

Am J Gastroenterol 2022 May 9. Epub 2022 May 9.

Clinical Enteric Neuroscience and Translational and Epidemiological Research (CENTER), Division of Gastroenterology and Hepatology.

Background: Cannabidiol (CBD), a CBR2 agonist with limited psychic effects, antagonizes CB1/CB2 receptors. Allelic variation CNR1 (gene for CBR1) rs806378 and FAAH rs324420 were associated with altered gut motility and sensation. This study aimed to compare pharmacodynamics and clinical effects of 4-week treatment with pharmaceutical grade CBD vs. Read More

Am J Gastroenterol 2022 May 5. Epub 2022 May 5.

Division of Gastroenterology, Warren Alpert School of Medicine, Brown University, Providence, RI.

Introduction: Antimicrobial resistance among Helicobacter pylori (H. pylori) strains has been rising globally, leading to declining eradication rates. We performed a systematic review and meta-analysis of the resistance patterns of H. Read More

Am J Gastroenterol 2022 May 5. Epub 2022 May 5.

Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China.

Am J Gastroenterol 2022 06 4;117(6):937-946. Epub 2022 May 4.

Gastrointestinal Diseases Research Unit, Queen's University, Kingston General Hospital, Kingston, Ontario, Canada.

There has been a dramatic increase in clinical studies examining the relationship between disorders of gut-brain interactions and symptoms evoked by food ingestion in the upper and lower gastrointestinal tract, but study design is challenging to verify valid endpoints. Consequently, mechanistic studies demonstrating biological relevance, biomarkers and novel therapeutic targets are greatly needed. This review highlights emerging mechanisms related to nutrient sensing and tasting, maldigestion, physical effects with underlying visceral hypersensitivity, allergy and immune mechanisms, food-microbiota interactions and gut-brain signaling, with a focus on patients with functional dyspepsia and irritable bowel syndrome. Read More

Am J Gastroenterol 2022 May 4. Epub 2022 May 4.

Department of Gastroenterology, Sapporo Kosei General Hospital, Sapporo, Japan.

Am J Gastroenterol 2022 May 4. Epub 2022 May 4.

Department of Applied Statistics, Yonsei University, Seoul 03722, South Korea.

Objectives: We investigated cardiovascular risk due to proton pump inhibitor (PPI) treatment using a self-controlled case series (SCCS) study design, a type of case-only design and an approach to overcome between-person confounding in which individuals act as their own control.

Methods: We conducted an SCCS study using the National Health Insurance Service-Health Screening cohort in Korea (2002-2015). The cohort included 303,404 adult participants without prior cardiovascular events, who were followed up until December 2015. Read More

Am J Gastroenterol 2022 May 4. Epub 2022 May 4.

Department of Gastroenterology, Changhai Hospital, Second/Navy Military Medical University, Shanghai, China.

Am J Gastroenterol 2022 06 4;117(6):827-830. Epub 2022 May 4.

MedStar Franklin Square Center for Digestive Disease, Baltimore, Maryland, USA.

Am J Gastroenterol 2022 May 4. Epub 2022 May 4.

Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN.

Am J Gastroenterol 2022 May 4. Epub 2022 May 4.

Department of Gastroenterology and Hepatology, University of Alabama at Birmingham, Birmingham, AL, USA.

Am J Gastroenterol 2022 06 4;117(6):821. Epub 2022 May 4.

Virginia Commonwealth University and Central Virginia Veterans Health Care System, Richmond, Virginia, USA.