396,923 results match your criteria American Journal Of Emergency Medicine[Journal]

Delay in Hip Fracture Repair in the Elderly: A Missed Opportunity Towards Achieving Better Outcomes.

J Surg Res 2021 May 11;266:142-147. Epub 2021 May 11.

Department of Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois; Department of Surgery, University of Michigan Health System, Ann Arbor, Michigan. Electronic address:

Background: Hip fractures are a major cause of morbidity and mortality in the elderly. The American Academy of Orthopedic Surgeons (AAOS) recommends surgical repair within 48 hours of admission, as this is associated with lower postoperative mortality and complications. This study demonstrates the association between patient demographics, level of care, and hospital region to delay in hip fracture repair in the elderly. Read More

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Associations between private well water and community water supply arsenic concentrations in the conterminous United States.

Sci Total Environ 2021 May 6;787:147555. Epub 2021 May 6.

Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, NY, USA.

Geogenic arsenic contamination typically occurs in groundwater as opposed to surface water supplies. Groundwater is a major source for many community water systems (CWSs) in the United States (US). Although the US Environmental Protection Agency sets the maximum contaminant level (MCL enforceable since 2006: 10 μg/L) for arsenic in CWSs, private wells are not federally regulated. Read More

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Even Mists Have Silver Linings: Promoting LGBTQ+ Acceptance and Solidarity through Community-Based Theatre in India.

Public Health 2021 May 12;194:252-259. Epub 2021 May 12.

Department of Community Health and Epidemiology, University of Saskatchewan, Canada.

Objectives: This project aimed to assess the effectiveness of a community-based theatre intervention to improve attitudes towards and increase knowledge about LGBTQ+ communities among audiences in Mumbai, India.

Study Design: This study was a program evaluation using pre- and post-show surveys that incorporated an adapted version of The Riddle Scale: Attitudes Towards Difference and questions assessing self-reported knowledge about LGBTQ+-related issues to assess changes in attitudes and knowledge after viewing the theatre intervention.

Methods: An original 90-min devised play was created by a company of Indian, American, and Canadian theatre artists using Participatory Action Research methods and was designed to bring audiences to a deeper understanding of LGBTQ+ identity. Read More

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Age, Gender, and Laterality of Retinal Vascular Occlusion: A Retrospective Study from the IRIS® Registry.

Ophthalmol Retina 2021 May 12. Epub 2021 May 12.

Schepens Eye Research Institute of Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA 02114, USA. Electronic address:

Purpose: Retinal vascular occlusion is a leading cause of profound irreversible visual loss, but the understanding of the disease is insufficient. We systematically investigated the age, gender, and laterality at the onset of retinal artery occlusion (RAO) and retinal vein occlusion (RVO) in the IRIS® Registry (Intelligent Research in Sight).

Design: A retrospective registry cohort. Read More

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Sleep disturbance in school-aged children with atopic dermatitis: prevalence and severity in a cross-sectional sample.

J Allergy Clin Immunol Pract 2021 May 12. Epub 2021 May 12.

Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611.

Rationale: Atopic dermatitis(AD) causes sleep disturbance, yet the epidemiology is not known.

Objective: Estimate the US prevalence of sleep disturbance and its impact on psychological and neurocognitive function.

Methods: Cross-sectional survey of 180 parent-child dyads with AD, using stratified sampling based on disease severity(POEM,Patient Oriented Eczema Measure,mild(n=30)/moderate(n=75)/severe (n=75)), age, and race (White/Black or African American/Other). Read More

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An Interprofessional Collaborative Practice Can Reduce Heart Failure Hospital Readmissions and Costs in an Underserved Population.

J Card Fail 2021 May 12. Epub 2021 May 12.

University of Alabama at Birmingham, Division of Cardiovascular Disease.

Background: Heart failure is a leading cause of hospitalization among adults in the United States. Nurse-led interprofessional clinics have been shown to improve heart failure outcomes in patients with heart failure, specifically reducing readmission rates. Yet, there is little information on the impact of nurse-led interprofessional collaborative practice within an underserved population with heart failure. Read More

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Long Term Outcomes After Arthroscopic Transosseous Equivalent Repair: Clinical and MRI Results of Rotator Cuff Tears at a Minimum Follow-up of 10 Years.

J Shoulder Elbow Surg 2021 May 12. Epub 2021 May 12.

Department of Orthopedics and Traumatology, Koc University School of Medicine, Istanbul, Turkey. Electronic address:

Purpose: The objective of this study was to evaluate long-term functional outcomes and structural integrity of medium to massive rotator cuff tears at 10 to 12 years of follow-up after arthroscopic transosseous equivalent repair (TOE).

Methods: A retrospective view was performed on a consecutive series of patients who underwent primary arthroscopic TOE repair of medium to massive size degenerative rotator cuff tears by a single surgeon between January 2007 and August 2009. Patients were examined at a minimum follow-up of 10 years and magnetic resonance imaging (MRI) was performed to assess tendon integrity. Read More

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Effect of thoracic spinal cord injury on forelimb somatosensory evoked potential.

Brain Res Bull 2021 May 12. Epub 2021 May 12.

Department of Electrical Engineering, College of Engineering, American University of Sharjah, ESB-2018, Engineering Science Building, American University of Sharjah, University City, Sharjah, 26666, United Arab Emirate. Electronic address:

In this paper, we investigate the forelimbs somatosensory evoked potential (SSEP) signals, which are representative of the integrity of ascending sensory pathways and their stability as well as function, recorded from corresponding cortices, post thoracic spinal cord injury (SCI). We designed a series of distinctive transection SCI to investigate whether forelimbs SSEPs change after right T10 hemi-transection, T8 and T10 double hemi-transection and T8 complete transection in rat model of SCI. We used electrical stimuli to stimulate median nerves and recorded SSEPs from left and right somatosensory areas of both cortices. Read More

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Improvements in sleep-disordered breathing during acclimatization to 3800 m and the impact on cognitive function.

Physiol Rep 2021 May;9(9):e14827

Division of Biomedical Sciences, School of Medicine, University of California, Riverside, CA, USA.

Sojourners to high altitude often experience poor sleep quality due to sleep-disordered breathing. Additionally, multiple aspects of cognitive function are impaired at high altitude. However, the impact of acclimatization on sleep-disordered breathing and whether poor sleep is a major contributor to cognitive impairments at high altitude remains uncertain. Read More

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Cardiac autonomic regulation and joint hypermobility in adolescents with functional abdominal pain disorders.

Neurogastroenterol Motil 2021 May 15:e14165. Epub 2021 May 15.

Traumatic Stress Research Consortium, Kinsey Institute, Indiana University, Bloomington, IN, USA.

Background: Joint hypermobility (JH) is associated with autonomic nervous system dysregulation and functional abdominal pain disorders (FAPDs). Understanding the neurophysiological processes linking these conditions can inform clinical interventions. Autonomic activity regulates gastrointestinal (GI) sensorimotor function and may be a key mechanism. Read More

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Use of a machine learning-based smartphone app to detect the sunscreen features in a photograph and provide feature-based recommendation.

J Cosmet Dermatol 2021 May 15. Epub 2021 May 15.

College of Medical Sciences, Department of Dermatology.

Sunscreens have been used as photoprotective agents to prevent photoaging, photocarcinogenesis and photodermatoses. However, a recent study found that a significant proportion of patients are uneducated about proper sunscreen use, with about 40% of the patients unaware about the minimum sun protection factor (SPF) requirement set by the American Academy of Dermatology (AAD). Another study based on consumer reviews on Amazon. Read More

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Gender as a moderator of the association of military sexual trauma and posttraumatic stress symptoms.

J Clin Psychol 2021 May 15. Epub 2021 May 15.

Department of Psychology, Utah State University, Logan, Utah, USA.

Objective: The current study examined the moderating role of gender on the association of military sexual trauma (MST) type (harassment-only vs. assault) and posttraumatic stress symptoms (PTSS) using the 6-factor Anhedonia Model.

Methods: Participants were 1321 service members/veterans. Read More

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Top 100 influential manuscripts in obstructive sleep apnea: a bibliometric analysis.

Sleep Breath 2021 May 15. Epub 2021 May 15.

Department of Physiology, School of Basic Medical Sciences, Xinjiang Medical University, No. 393 Xinyi Road, Urumqi, Xinjiang, China.

Objective: This study aimed to explore the characteristics of the top 100 influential manuscripts on obstructive sleep apnea (OSA).

Methods: All manuscripts in English were searched from the Thomson Reuters Web of Science database by using OSA-related terms and ranked based on citation frequency. The top 100 influential manuscripts were selected and further analyzed by author, subject, journal, year of publication, country of origin, and institution. Read More

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Perceived Social Support from Different Sources and Adolescent Life Satisfaction Across 42 Countries/Regions: The Moderating Role of National-Level Generalized Trust.

J Youth Adolesc 2021 May 15. Epub 2021 May 15.

Department of Interdisciplinary Social Science, Utrecht University, Padualaan 14, 3584 CH, Utrecht, The Netherlands.

Although previous research established a positive association between perceived social support and adolescent life satisfaction, little is known about the relative importance of different sources of support for adolescent life satisfaction and cross-country variations in this respect. Using large-scale representative samples from the 2017/18 Health Behaviour in School-aged Children (HBSC) study, this study examined to what extent the association between social support and life satisfaction in early adolescence varied across different social sources and countries. Also, it examined whether cross-country variations are explained by national-level generalized trust, a sociocultural factor that shapes adolescent socialization. Read More

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Intersections of Racial Discrimination and LGB Victimization for Mental Health: A Prospective Study of Sexual Minority Youth of Color.

J Youth Adolesc 2021 May 15. Epub 2021 May 15.

Department of Human Development and Family Sciences, University of Texas at Austin, SEA 2.444 108 E. Dean Keeton St., Stop A2702, Austin, TX, 78712, USA.

Sexual minority youth (i.e., lesbian, gay, and bisexual youth; LGB) of color have multiple minoritized identities, and few studies examine the implications of intersectional minority stressors for their prospective mental health. Read More

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Empathy as a Mediator of the Relationship between Authoritative Parenting and Delinquent Behavior in Adolescence.

J Youth Adolesc 2021 May 15. Epub 2021 May 15.

Department of Psychology, University of Alabama at Birmingham, 1720 2nd Avenue South, CH415, Birmingham, AL, 35294, USA.

The characteristics of authoritative parenting, including high parental nurturance and appropriate control, are protective against adolescents' delinquency. However, the mediating psychological mechanisms are not well understood. This three-wave longitudinal study with 704 adolescents (52% males; 76% African American) investigated empathy at age 13 as a mediator of the prospective association between authoritative parenting (child's disclosure and parental nurturance) at age 11 with delinquency at age 18. Read More

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Total knee arthroplasty is associated with greater immediate post-surgical pain and opioid use than total hip arthroplasty.

Arch Orthop Trauma Surg 2021 May 15. Epub 2021 May 15.

New York University Langone Orthopaedic Hospital, 301 East 17 St, Manhattan, New York, NY, 10003, USA.

Background: As greater emphasis is being placed on opioid reduction strategies and implementation of multimodal analgesia, we sought to determine whether immediate post-surgical opioid consumption was different between THA and TKA.

Methods: A single-institution total joint arthroplasty database was used to identify patients who underwent elective THA and TKA from 2016 to July 2019. Baseline demographic data, operative time (defined by incision time), and American Society of Anesthesiologist (ASA) class were collected. Read More

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Effects of the new fasting standard on sedation in the pediatric emergency room.

Pediatr Int 2021 May 15. Epub 2021 May 15.

National Center for Global Health and Medicine. Bureau of International Health Cooperation. Department of Human Resources Development.

Background: The present study compared adherence to the fasting-time guidelines of the International Committee for the Advancement of Procedural Sedation (ICAPS) and the North American Society of Anesthesiologists (ASA) and complication rates in pediatric patients requiring procedure sedation and analgesia during treatment in the emergency room (ER).

Methods: The present, retrospective, single-center study was performed between 2016 and 2020 and enrolled patients who received procedural sedation and analgesia in the ER with the fasting times recommended in the ICAPS and ASA guidelines.

Results: In total, 857 patients were included. Read More

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In vitro effects of aqueous extract of fermented rooibos (Aspalathus linearis) on human sperm function.

Andrologia 2021 May 15:e14114. Epub 2021 May 15.

Department of Pre-Clinical Sciences, University of Limpopo, Polokwane, South Africa.

Aspalathus linearis (rooibos) is a herbal medicinal plant originally from South Africa's fynbos and well known for its medicinal effects in treating different medical conditions. Rooibos contains significant levels of antioxidants capable of inhibiting the production of reactive oxygen species, which may improve seminal parameters. This study focussed on investigating the direct effect of fermented rooibos on human sperm functions in vitro. Read More

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Comparison of Guidelines for the Use of Ustekinumab for Psoriasis in the United States, Europe, and the United Kingdom: A Critical Appraisal and Comprehensive Review.

Dermatol Ther 2021 May 14:e14974. Epub 2021 May 14.

Dermatology Research and Education Foundation, Irvine, CA, USA.

Purpose: The aim of this review is to compare and contrast evidence-based clinical practice guidelines from global dermatological organizations for the use of ustekinumab in psoriasis.

Materials And Methods: Clinical practice guidelines from the American Academy of Dermatology (AAD), National Psoriasis Foundation (NPF), British Association of Dermatologists (BAD), and European S3 were reviewed and compared.

Results: Practice guidelines from the three dermatological organizations are similar with regards to treatment dosage and initiation but differ in their recommendations for baseline screening and interval laboratory monitoring, treatment in patients undergoing surgery or receiving live vaccines, and treatment contraindications. Read More

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Concurrent and predictive validity of AND-ASPEN Malnutrition Consensus is satisfactory in hospitalized patients: a longitudinal study - A Commentary.

JPEN J Parenter Enteral Nutr 2021 May 14. Epub 2021 May 14.

Special Projects Consultant, American Society for Parenteral and Enteral Nutrition (ASPEN).

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Population-based cancer staging for oesophageal, gastric, and pancreatic cancer 2012-2014: International Cancer Benchmarking Partnership SurvMark-2.

Int J Cancer 2021 May 14. Epub 2021 May 14.

Cancer Surveillance Branch, International Agency for Research on Cancer, Lyon, France.

Cancer stage at diagnosis is important information for management and treatment of individual patients as well as in epidemiological studies to evaluate effectiveness of health care system in managing cancer patients. Population-based studies to examine international disparities on cancer survival by stage, however, has been challenging due to the lack of international standardization on recording stage information and variation in stage completeness across regions and countries. The International Cancer Benchmarking Partnership (ICBP) previously assessed the availability and comparability of staging information for colorectal, lung, female breast, and ovarian cancers. Read More

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Grand rounds education in neurology, with a focus on headache medicine.

Headache 2021 May 15. Epub 2021 May 15.

Department of Neurology, Mayo Clinic Arizona, Scottsdale, AZ, USA.

Objective: To quantify the proportion of headache-related grand rounds in academic neurology programs and to compare this with adult neurology residency director views on the need for an increase in headache-related grand rounds.

Background: Although headache are among the most prevalent and most burdensome neurologic conditions, headache medicine is often considered underrepresented in neurology departments. Additionally, prior studies have shown that many neurology residency directors feel that training programs do not include an adequate amount of exposure to headache clinics or headache-related didactics. Read More

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Efficacy and safety of jakinibs in rheumatoid arthritis: a systematic review and meta-analysis.

Clin Rheumatol 2021 May 14. Epub 2021 May 14.

Department of Rheumatology, The First Affiliated Hospital of Soochow University, No. 188 Shizi St, Suzhou, 215006, Jiangsu, China.

Objectives: To assess the efficacy and safety of jakinibs for the treatment of active rheumatoid arthritis (RA) in patients with an inadequate response or intolerance to conventional synthetic or biologic disease-modifying antirheumatic drugs (DMARDs).

Methods: A systematic search was conducted in PubMed, Embase, and the Cochrane Library. Randomized placebo-controlled trials (RCTs) of jakinibs in RA patients were eligible. Read More

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How palliative care teams can mitigate financial toxicity in cancer care.

Support Care Cancer 2021 May 14. Epub 2021 May 14.

Surveillance and Health Services Research, American Cancer Society, Atlanta, GA, USA.

The disruption to patient and family well-being introduced by the rising costs of cancer care is a growing clinical problem. In addition to logistical questions, there is a compelling, existential one: "How should healthcare teams address patient and caregiver distress and uncertainty from financial toxicity?" We argue that the principles and practice of palliative care can help alleviate this element and often unaddressed component of human suffering. Read More

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Trauma exposure and stress-related disorders in a large, urban, predominantly African-American, female sample.

Arch Womens Ment Health 2021 May 15. Epub 2021 May 15.

Department of Psychiatry and Behavioral Sciences, Yerkes National Primate Research Center, Emory University School of Medicine, 954 Gatewood Rd, Atlanta, GA, 30329, USA.

The current study investigated the relationship between trauma exposure and psychopathology in a sample of predominately African-American women of low socioeconomic status (SES). Women (N = 7430) were recruited from medical clinics at two large public hospitals in Atlanta, GA, from 2005 to 2017. Women were assessed for sociodemographics, life-course trauma burden, posttraumatic stress disorder (PTSD), and major depressive disorder (MDD) utilizing self-report and structured clinical interview assessments. Read More

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An ensemble of neural networks provides expert-level prenatal detection of complex congenital heart disease.

Nat Med 2021 May 14;27(5):882-891. Epub 2021 May 14.

Division of Cardiology, Department of Pediatrics, University of California, San Francisco,, San Francisco, CA, USA.

Congenital heart disease (CHD) is the most common birth defect. Fetal screening ultrasound provides five views of the heart that together can detect 90% of complex CHD, but in practice, sensitivity is as low as 30%. Here, using 107,823 images from 1,326 retrospective echocardiograms and screening ultrasounds from 18- to 24-week fetuses, we trained an ensemble of neural networks to identify recommended cardiac views and distinguish between normal hearts and complex CHD. Read More

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Epigenome-wide association meta-analysis of DNA methylation with coffee and tea consumption.

Nat Commun 2021 May 14;12(1):2830. Epub 2021 May 14.

Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, the Netherlands.

Coffee and tea are extensively consumed beverages worldwide which have received considerable attention regarding health. Intake of these beverages is consistently linked to, among others, reduced risk of diabetes and liver diseases; however, the mechanisms of action remain elusive. Epigenetics is suggested as a mechanism mediating the effects of dietary and lifestyle factors on disease onset. Read More

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