Am J Clin Nutr 2022 May 12. Epub 2022 May 12.
Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.
Background: The benefit of a Mediterranean-style diet in reducing frailty is not well established in older Americans.
Objective: To determine associations of a Mediterranean-style dietary pattern and related antioxidants with frailty onset and worsening of the Fried Phenotype in adults.
Design And Methods: This prospective study included 2,384 non-frail adults from the Framingham Offspring Study with Mediterranean-style dietary pattern score (MSDPS) and antioxidant intakes [vitamin C, E, and total carotenoids] estimated from a food frequency questionnaire (FFQ) at the index examination (1998-2001) and one prior examination (if available), and frailty assessment at the index examination and at least 1 follow-up. Read More