9 results match your criteria American Journal Of Chinese Medicine[Journal]

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Efficacy of leflunomide combined with ligustrazine in the treatment of rheumatoid arthritis: prediction with network pharmacology and validation in a clinical trial.

Chin Med 2019 2;14:26. Epub 2019 Aug 2.

2School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Kowloon, Hong Kong.

Background: Leflunomide (LEF) is a first-line disease-modifying antirheumatic drug (DMARD) for rheumatoid arthritis (RA). However, there are still a few nonresponders. It is logical to suggest that employing combinations including LEF that produce synergistic effects in terms of pharmacological activity is a promising strategy to improve clinical outcomes. Read More

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Anti-tumor effects of the American cockroach, .

Chin Med 2017 12;12:26. Epub 2017 Sep 12.

Modern Research Center for Traditional Chinese Medicine, School of Chinese Materia Medica, Beijing University of Chinese Medicine, No.11 North Third Ring Road, Chaoyang District, Beijing, 100029 China.

Since the incidence of cancer has been on the rise due to increasing exposure to various carcinogenic factors in recent years, cancer has gradually become the first killer to the health of human beings. A growing attention has been paid to anti-cancer effects of traditional Chinese medicine (TCM) with low toxicity and good efficacy. As a kind of TCM, () has a good effect on clinical application, and its anti-tumor effects has been increasingly well studied. Read More

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September 2017

High-throughput sequencing technology reveals that continuous cropping of American ginseng results in changes in the microbial community in arable soil.

Chin Med 2017 3;12:18. Epub 2017 Jul 3.

Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, 100700 China.

Background: American ginseng ( L.) is renowned worldwide for its eutherapeutic effects. The replantation of American ginseng usually fails due to problems associated with continuous cropping. Read More

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Identification of constituent herbs in ginseng decoctions by DNA markers.

Chin Med 2015 30;10(1). Epub 2015 Jan 30.

School of Life Sciences, The Chinese University of Hong Kong, S.A.R N.T, Shatin, Hong Kong China ; State Key Laboratory of Phytochemistry and Plant Resources in West China (CUHK), Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong China.

Background: DNA in herbal decoctions is usually fragmented by extensive boiling and is usually regarded as unsuitable for molecular authentication. This study aims to evaluate the feasibility for molecular authentication methods by multiplex polymerase chain reaction (PCR) and DNA sequencing for decoctions.

Methods: The DNA extraction procedure, sample pulverization and boiling time were examined in (1) single herb decoction with Panax ginseng ("ginseng") or P. Read More

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February 2015

Metabonomic analysis of water extracts from Chinese and American ginsengs by 1H nuclear magnetic resonance: identification of chemical profile for quality control.

Chin Med 2012 Nov 12;7(1):25. Epub 2012 Nov 12.

Department of Chemical and Biomolecular Engineering, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China.


Background: With the gaining popularity of commercially prepared decoctions of herbal medicines on the market, an objective and efficient way to reveal the authenticity of such products is urgently needed. Previous attempts to use chromatographic or spectroscopic methods to identify ginseng samples made use of components derived from methanol extracts of the herb. It was not established that these herbs can be distinguished solely from consumable components, which are responsible for the clinical efficacy of the herb. Read More

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November 2012

The Yin and Yang actions of North American ginseng root in modulating the immune function of macrophages.

Chin Med 2011 May 27;6(1):21. Epub 2011 May 27.

Ontario Ginseng Innovation and Research Consortium, the University of Western Ontario, London, Ontario, N6A 5C1, Canada.

Background: Immuno-modulatory effects of ginseng, including both immuno-stimulatory and immuno-suppressive effects, have been widely reported. This study aims to determine whether the paradoxical immuno-modulatory effect is related to unique phytochemical profiles of different North American (NA) ginseng, namely aqueous (AQ) and alcoholic (ALC) extracts.

Methods: AQ and ALC extracts were prepared and their immuno-bioactivity were studied in vitro in murine macrophages (Raw 264. Read More

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Perception of Deqi by Chinese and American acupuncturists: a pilot survey.

Chin Med 2011 Jan 20;6(1). Epub 2011 Jan 20.

Department of Radiology, Massachusetts General Hospital & Harvard Medical School, Charlestown, Massachusetts, 02129, USA.

Background: In acupuncture, deqi is the sensory experience related to clinical efficacy. As the first study taking into account cultural differences on deqi sensation, this pilot survey aims to corroborate the acupuncturists' general experience in clinical practice with functional magnetic resonance imaging (fMRI) findings.

Methods: Questionnaires were distributed to acupuncturists of TCM (traditional Chinese medicine)hospitals and acupuncturists attending workshops and seminars in the United States and China. Read More

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January 2011

Significant differences in alkaloid content of Coptis chinensis (Huanglian), from its related American species.

Chin Med 2009 Aug 24;4:17. Epub 2009 Aug 24.

Department of Chemistry, St Lawrence University, Canton, New York 13617, USA.

Background: The growing popularity of Chinese herbal medicine in the United States has prompted large-scale import of raw herbs from Asia. Many of the Asian herbs have phylogenetically related North American species. We compared three phylogenetically related species, namely Coptis chinensis (Huanglian), Hydrastis canadensis and Coptis trifolia to show whether they can be substituted by one another in terms of alkaloid content. Read More

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American ginseng modulates pancreatic beta cell activities.

Chin Med 2007 Oct 25;2:11. Epub 2007 Oct 25.

Department of Cardiology, Second Affiliated Hospital, Second Military Medical University, Shanghai, China.

The mechanism of the beneficial effects of Panax quinquefolius (Xiyangshen, American ginseng) on diabetes is yet to be elucidated. Recent studies show that Panax quinquefolius increases insulin production and reduces the death of pancreatic beta cells. Mechanism studies indicate that Panax quinquefolius improves cell's immuno-reactivity and mitochondrial function through various factors. Read More

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October 2007
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