368,699 results match your criteria American Health & Drug Benefits [Journal]


Levels of Employment and Community Engagement among Low-Income Adults: Implications for Medicaid Work Requirements.

J Health Polit Policy Law 2020 May 28. Epub 2020 May 28.

Harvard University.

Context: Twenty states are pursuing community engagement requirements ("work requirements") in Medicaid, though legal challenges are ongoing. While most non-disabled low-income individuals work, it is less clear how many engage in the required number of hours of qualifying community engagement activities, and what heterogeneity may exist by race/ethnicity, age, and gender. Our objective was to estimate current levels of employment and other community engagement activities among potential Medicaid beneficiaries. Read More

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http://dx.doi.org/10.1215/03616878-8641567DOI Listing

Improving Quality as a Solution to the Health Care Cost Problem? Health Policy Experts and the Promotion of a Controversial Idea.

Authors:
Ulrike Lepont

J Health Polit Policy Law 2020 May 28. Epub 2020 May 28.

Université de Versailles Saint-Quentin-en-Yvelines.

Context: In the late 2000s, the contention that quality improvements achieved by reforms in the delivery of care would slow the growth of costs throughout the US health care system became the predominant strategy for cost-containment in the discourses and programs of all the 2008 presidential candidates. To understand why, in spite of all the critiques made of this idea, especially those of the CBO, the "quality solution" remained credible enough to be a possible argument in policymakers' discourses and programs. This article explores the role of health policy experts-one of whose crucial roles is to give credibility and legitimacy to proposals defended by policymakers-in supporting and diffusing what I call the "quality solution. Read More

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http://dx.doi.org/10.1215/03616878-8641579DOI Listing

Racism and the Political Economy of COVID-19: Will We Continue to Resurrect the Past?

J Health Polit Policy Law 2020 May 28. Epub 2020 May 28.

CUNY Institute for Health Equity.

COVID-19 is not spreading over a level playing field; structural racism is embedded within the fabric of American culture, infrastructure investments, and public policy, and fundamentally drives inequities. The same racism that has driven the systematic dismantling of the American social safety-net has also created the policy recipe for American structural vulnerability to the impacts of this and other pandemics. The Bronx provides an important case study for investigating the historical roots of structural inequities showcased by this pandemic; current lived experiences of Bronx residents are rooted in the racialized dismantling of New York City's public infrastructure and systematic disinvestment. Read More

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http://dx.doi.org/10.1215/03616878-8641481DOI Listing

Slow blood-to-brain transport underlies enduring barrier dysfunction in American football players.

Brain 2020 May 28. Epub 2020 May 28.

Departments of Physiology and Cell Biology, Brain and Cognitive Sciences, The Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

Repetitive mild traumatic brain injury in American football players has garnered increasing public attention following reports of chronic traumatic encephalopathy, a progressive tauopathy. While the mechanisms underlying repetitive mild traumatic brain injury-induced neurodegeneration are unknown and antemortem diagnostic tests are not available, neuropathology studies suggest a pathogenic role for microvascular injury, specifically blood-brain barrier dysfunction. Thus, our main objective was to demonstrate the effectiveness of a modified dynamic contrast-enhanced MRI approach we have developed to detect impairments in brain microvascular function. Read More

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http://dx.doi.org/10.1093/brain/awaa140DOI Listing

Equitable Pandemic Preparedness and Rapid Response: Lessons from COVID-19 for Pandemic Health Equity.

J Health Polit Policy Law 2020 May 28. Epub 2020 May 28.

Vanderbilt University Medical Center.

The novel coronavirus pandemic has set in high relief the entrenched health, social, racial, political, and economic inequities within American society as the incidence of severe morbidity and mortality from the disease caused by the virus appears to be much greater in Black and other racial/ethnic minority populations, within homeless and incarcerated populations, and in lower-income communities in general. The reality is that the U.S. Read More

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http://dx.doi.org/10.1215/03616878-8641469DOI Listing

Favorable outcome after COVID-19 infection in a multiple sclerosis patient initiated on ocrelizumab during the pandemic.

Mult Scler Relat Disord 2020 May 23;43:102222. Epub 2020 May 23.

Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.msard.2020.102222DOI Listing

Overview on Dirofilaria immitis in the Americas, with notes on other filarial worms infecting dogs.

Vet Parasitol 2020 May 12;282:109113. Epub 2020 May 12.

Department of Veterinary Medicine, University of Bari, Valenzano, Italy; Faculty of Veterinary Sciences, Bu-Ali Sina University, Hamedan, Iran.

Canine dirofilariosis in the Americas is primarily caused by Dirofilaria immitis, a mosquito-borne filarial worm infecting dogs, which may also infect and cause disease in other mammalian hosts, including humans. Morphological and molecular evidence gathered in the past decades suggest that other Dirofilaria spp. may infect dogs in the American continent, though the actual taxonomic identity of them still needs to be elucidated. Read More

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http://dx.doi.org/10.1016/j.vetpar.2020.109113DOI Listing

Association between central sleep apnea and atrial fibrillation/flutter in Japanese-American men: The Kuakini Honolulu Heart Program (HHP) and Honolulu-Asia Aging Study (HAAS).

J Electrocardiol 2020 May 12;61:10-17. Epub 2020 May 12.

University of Hawai'i at Mānoa, Department of Geriatric Medicine, John A. Burns School of Medicine, 347 N Kuakini St, Honolulu, HI, USA; Kuakini Medical Center, 347 N Kuakini St, Honolulu, HI, USA. Electronic address:

Introduction: While several studies have indicated that central sleep apnea (CSA) is associated with atrial fibrillation and atrial flutter (AF) in older populations, few studies have focused on older Asian populations.

Methods: We conducted a cross- sectional analysis using data from the 1999-2000, 7th exam cycle of the Kuakini Honolulu-Asia Aging Study. Participants were 718 Japanese-American men between 79 and 97 years old, who had overnight polysomnography. Read More

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http://dx.doi.org/10.1016/j.jelectrocard.2020.05.005DOI Listing

Selective in vitro and in silico enzymes inhibitory activities of phenolic acids and flavonoids of food plants: Relations with oxidative stress.

Food Chem 2020 May 19;327:127045. Epub 2020 May 19.

Department of General and Analytical Chemistry, Faculty of Pharmacy, Istanbul University, 34116 Istanbul, Turkey.

In this study, the inhibitory potentials of food originated 34 phenolic acids, and flavonoid compounds were screened against acetylcholinesterase, butyrylcholinesterase, urease, and tyrosinase enzymes. All compounds included in this study exhibited high antioxidant activity with an ignorable cytotoxic activity. In general, they also showed poor anti-urease and anti-tyrosinase activities. Read More

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http://dx.doi.org/10.1016/j.foodchem.2020.127045DOI Listing

Governance of mental healthcare: Fragmented accountability.

Soc Sci Med 2020 Apr 22;255:113007. Epub 2020 Apr 22.

Addictions and Mental Health Ontario, Toronto, Canada.

Within international healthcare systems the neglect of mental health and challenge in shifting from institutional to community care have been recurrent themes. In analysing the challenges, we focus on the case study of Canada by exploring the manner in which health law and policy evolved to inhibit community-based mental healthcare, and compare the resulting funding landscape from an international perspective. The historical institutionalist analysis draws on the literature and healthcare finance data. Read More

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http://dx.doi.org/10.1016/j.socscimed.2020.113007DOI Listing

The neurology of COVID-19 revisited: A proposal from the Environmental Neurology Specialty Group of the World Federation of Neurology to implement international neurological registries.

J Neurol Sci 2020 May 7;414:116884. Epub 2020 May 7.

Pakistan International Neuroscience Society, Neurology, Aga Khan University, Karachi, Pakistan.

A comprehensive review of the neurological disorders reported during the current COVID-19 pandemic demonstrates that infection with SARS-CoV-2 affects the central nervous system (CNS), the peripheral nervous system (PNS) and the muscle. CNS manifestations include: headache and decreased responsiveness considered initial indicators of potential neurological involvement; anosmia, hyposmia, hypogeusia, and dysgeusia are frequent early symptoms of coronavirus infection. Respiratory failure, the lethal manifestation of COVID-19, responsible for 264,679 deaths worldwide, is probably neurogenic in origin and may result from the viral invasion of cranial nerve I, progressing into rhinencephalon and brainstem respiratory centers. Read More

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http://dx.doi.org/10.1016/j.jns.2020.116884DOI Listing

Genetics and epigenetics of ibd.

Authors:
Vito Annese

Pharmacol Res 2020 May 25:104892. Epub 2020 May 25.

Head of Gastroenterology and Medical Director, Valiant Clinic, Dubai, United Arab Emirates; CBP American Hospital, Dubai, United Arab Emirates; Aggregate Professor United Arabian Emirates University, College of Medicine & Health Science, Al Ain, United Arab Emirates. Electronic address:

Inflammatory bowel diseases (IBD) are chronic intermittent inflammatory disorders of the gastrointestinal tract of unknown etiology but a clear genetic predisposition. Prompted by the first investigations on IBD families and twins, the genetic and epigenetic studies have produced an unprecedented amount of information in comparison with other immune-mediated or complex diseases. New inflammatory pathways and possible mechanisms of action have been disclosed, potentially leading to new-targeted therapy. Read More

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http://dx.doi.org/10.1016/j.phrs.2020.104892DOI Listing

Welfare of horses from Mexico and the United States of America transported for slaughter in Mexico: Fitness profiles for transport and pre-slaughter logistics.

Prev Vet Med 2020 May 16;180:105033. Epub 2020 May 16.

Department of Animal Production & Food Science, Agri-Food Institute of Aragon (IA2), University of Zaragoza, Zaragoza, Spain.

Every year thousands of horses from Mexico and the United States of America (USA) are transported to slaughter in Mexico, but little is known about their welfare or pre-slaughter logistics. In this study, we recorded the origin, sex, age and condition of horses (121 journeys, 2648 animals) upon arrival to an abattoir in northern Mexico, including transport details. Horse welfare was measured indirectly via individual scores for body condition, coat quality, lameness, ocular and nasal discharge, as well as reactivity to a chute restraint test, all performed shortly after unloading. Read More

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http://dx.doi.org/10.1016/j.prevetmed.2020.105033DOI Listing

Summary for Clinicians: 2019 Clinical Practice Guideline Summary for the Treatment of Drug-Resistant Tuberculosis.

Ann Am Thorac Soc 2020 May 28. Epub 2020 May 28.

Mt Auburn Hospital, Pulmonary and Critical Care, Cambridge, Massachusetts, United States.

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http://dx.doi.org/10.1513/AnnalsATS.202004-318CMEDOI Listing

Baseline cardiovascular risk assessment in cancer patients scheduled to receive cardiotoxic cancer therapies: a Position Statement and new risk assessment tools from the Cardio-Oncology Study Group of the Heart Failure Association of the European Society of Cardiology in collaboration with the International Cardio-Oncology Society.

Eur J Heart Fail 2020 May 28. Epub 2020 May 28.

Cardio-Oncology Center of Excellence, Washington University in St Louis, Missouri, USA.

This position statement from the Heart Failure Association of the European Society of Cardiology Cardio-Oncology Study Group in collaboration with the International Cardio-Oncology Society presents practical, easy-to-use and evidence-based risk stratification tools for oncologists, haemato-oncologists and cardiologists to use in their clinical practice to risk stratify oncology patients prior to receiving cancer therapies known to cause heart failure or other serious cardiovascular toxicities. Baseline risk stratification proformas are presented for oncology patients prior to receiving the following cancer therapies: anthracycline chemotherapy, HER2-targeted therapies such as trastuzumab, vascular endothelial growth factor inhibitors, second and third generation multi-targeted kinase inhibitors for CML targeting BCR-ABL, multiple myeloma therapies (proteasome inhibitors and immunomodulatory drugs), RAF and MEK inhibitors or androgen deprivation therapies. Applying these risk stratification proformas will allow clinicians to stratify cancer patients into low, medium, high and very high risk of cardiovascular complications prior to starting treatment, with the aim of improving personalised approaches to minimise the risk of cardiovascular toxicity from cancer therapies. Read More

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http://dx.doi.org/10.1002/ejhf.1920DOI Listing

The gut microbiota of invasive bullfrog tadpoles responds more rapidly to temperature than a non-invasive congener.

Mol Ecol 2020 May 28. Epub 2020 May 28.

Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA, 15260, USA.

Environmental temperature can alter the composition, diversity, and function of ectothermic vertebrate gut microbial communities, which may result in negative consequences for host physiology, or conversely, increase phenotypic plasticity and persistence in harsh conditions. The magnitude of either of these effects will depend on the length of time animals are exposed to extreme temperatures, and how quickly the composition and function of the gut microbiota can respond to temperature change. However, the temporal effects of temperature on gut microbiota are currently unknown. Read More

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http://dx.doi.org/10.1111/mec.15487DOI Listing

Generating a Cost-Effective, Weekend-Free Chemically Defined Human Induced Pluripotent Stem Cell (hiPSC) Culture Medium.

Curr Protoc Stem Cell Biol 2020 Jun;53(1):e110

Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

We have previously developed a cost-effective chemically defined medium formula for weekend-free culture of human induced pluripotent stem cells (hiPSCs), costing ∼3% of the price of commercial medium. This medium, which we termed B8, is specifically optimized for robust and fast growth of hiPSCs and for a weekend-free medium change regimen. We demonstrated that this medium is suitable for reprogramming of somatic cells into hiPSCs and for differentiation into a variety of lineages. Read More

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http://dx.doi.org/10.1002/cpsc.110DOI Listing

Extinguishing burnout: National analysis of predictors and effects of burnout in abdominal transplant surgery fellows.

Am J Transplant 2020 May 28. Epub 2020 May 28.

Cincinnati Research on Education in Surgical Training (CREST), Cincinnati, Ohio, USA.

Burnout among surgeons has been attributed to increased workload and decreased autonomy. Although prior studies have examined burnout among transplant surgeons, no studies have evaluated burnout in abdominal transplant surgery fellows. The objective of our study was to identify predictors of burnout and understand its impact on personal and patient care during fellowship. Read More

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http://dx.doi.org/10.1111/ajt.16075DOI Listing

Concordance between dermatologist self-reported and industry-reported interactions at a national dermatology conference.

Cutis 2020 Apr;105(4):203-208;E1

Division of Dermatology, Department of Internal Medicine, University of Texas at Austin, USA.

Physician-industry interactions are prevalent. Accurate reporting allows for transparency regarding potential conflicts of interest. We sought to compare the self-reported interactions in the American Academy of Dermatology (AAD) Annual Meeting disclosures with the industry-reported interactions in the Open Payments (OP) database. Read More

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HIV-related outcome disparities between transgender women living with HIV and cisgender people living with HIV served by the Health Resources and Services Administration's Ryan White HIV/AIDS Program: A retrospective study.

PLoS Med 2020 May 28;17(5):e1003125. Epub 2020 May 28.

Health Resources and Services Administration, HIV/AIDS Bureau, Rockville, Maryland, United States of America.

Background: In the United States, approximately one-fifth of transgender women are living with HIV-nearly one-half of Black/African American (Black) transgender women are living with HIV. Limited data are available on HIV-related clinical indicators among transgender women. This is because of a lack of robust transgender data collection and research, especially within demographic subgroups. Read More

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http://dx.doi.org/10.1371/journal.pmed.1003125DOI Listing

The differential effects of low dose sacubitril and/or valsartan on renal disease in salt-sensitive hypertension.

Am J Physiol Renal Physiol 2020 May 28. Epub 2020 May 28.

Department of Medicine, Division of Nephrology, Medical University of South Carolina, United States.

Diuretics and renin-angiotensin system (RAAS) blockers are often insufficient to control the blood pressure (BP) in salt-sensitive (SS) subjects. Abundant data support the proposal that level of Atrial Natriuretic Peptide (ANP) may correlate with pathogenesis of SS hypertension. We hypothesized here that increasing ANP level with sacubitril, combined with RAAS blockage by valsartan, can be beneficial for alleviation of renal damage in a model of SS hypertension, the Dahl SS rat. Read More

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http://dx.doi.org/10.1152/ajprenal.00125.2020DOI Listing

Newborn Circumcision Techniques.

Am Fam Physician 2020 Jun;101(11):680-685

Morehouse School of Medicine, Atlanta, GA, USA.

Newborn male circumcision is a common elective surgical procedure for the removal of foreskin covering the glans penis. The American Academy of Pediatrics, the American College of Obstetricians and Gynecologists, the Centers for Disease Control and Prevention, and the American Academy of Family Physicians recognize that there are health benefits of newborn male circumcision but do not universally recommend the procedure. Performing male circumcision during the neonatal period has several advantages, including a lower risk of complications, faster healing, and lower cost. Read More

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Assisted reproductive techniques in Latin America: The Latin American Registry, 2017.

JBRA Assist Reprod 2020 May 13. Epub 2020 May 13.

Latin American Network of Assisted Reproduction (REDLARA), Montevideo, Uruguay.

Research Question: What was the utilization, effectiveness and safety of assisted reproductive techniques performed in Latin America during 2017.

Design: Retrospective collection of multinational data on ART performed in 188 institutions from 15 Latin American countries.

Results: We are reporting 93,600 initiated cycles, 16,976 deliveries and the birth of 20,404 babies. Read More

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http://dx.doi.org/10.5935/1518-0557.20200029DOI Listing

Genetic Sequencing of Pediatric Patients Identifies Mutations in Monogenic Inflammatory Bowel Disease Genes that Translate to Distinct Clinical Phenotypes.

Clin Transl Gastroenterol 2020 Feb;11(2):e00129

Department of Human Genetics and Genomic Medicine, University of Southampton, Southampton, UK.

Objectives: Monogenic inflammatory bowel disease (IBD) comprises rare Mendelian causes of gut inflammation, often presenting in infants with severe and atypical disease. This study aimed to identify clinically relevant variants within 68 monogenic IBD genes in an unselected pediatric IBD cohort.

Methods: Whole exome sequencing was performed on patients with pediatric-onset disease. Read More

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http://dx.doi.org/10.14309/ctg.0000000000000129DOI Listing
February 2020

Salivary markers of oxidative stress and periodontal pathogens in patients with periodontitis from Santander, Colombia.

Biomedica 2020 May 1;40(Supl. 1):113-124. Epub 2020 May 1.

Facultad de Odontología, Universidad Antonio Nariño, Bucaramanga, Colombia.

Introduction: Periodontitis affects more than 20% of the Latin American population. Oxidative markers are associated with greater progression of periodontitis; therefore, its role in pathogenesis should be studied.

Objective: To determine the prevalence of the main oral bacteria and viruses associated with periodontitis and estimate the total antioxidant capacity and lipid peroxidation in saliva from patients with periodontitis. Read More

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http://dx.doi.org/10.7705/biomedica.5149DOI Listing

Assessment of Brix refractometry to estimate immunoglobulin G concentration in beef cow colostrum.

J Vet Intern Med 2020 May 28. Epub 2020 May 28.

Department of Production Animal Health, University of Calgary Faculty of Veterinary Medicine, Calgary, Alberta, Canada.

Background: Brix refractometry can be used to assess colostral immunoglobulin G (IgG) concentration, but studies identifying Brix percentages to detect high- and low-IgG colostrum are lacking for beef cows and interlaboratory agreement is unknown.

Objectives: Evaluate Brix refractometer performance and interlaboratory agreement for assessing beef cow colostrum IgG concentration, including determination of thresholds to identify colostrum containing IgG concentrations <100 g/L and ≥150 g/L.

Animals: Beef cows (n = 416) from 11 cow-calf operations in Alberta, Canada. Read More

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http://dx.doi.org/10.1111/jvim.15805DOI Listing

The pyruvate kinase (PK) to hexokinase enzyme activity ratio and erythrocyte PK protein level in the diagnosis and phenotype of PK deficiency.

Br J Haematol 2020 May 28. Epub 2020 May 28.

Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA, USA.

Diagnosis of pyruvate kinase deficiency (PKD), the most common cause of hereditary non-spherocytic haemolytic anaemia, remains challenging in routine practice and no biomarkers for clinical severity have been characterised. This prospective study enrolled 41 patients with molecularly confirmed PKD from nine North American centres to evaluate the diagnostic sensitivity of pyruvate kinase (PK) enzyme activity and PK:hexokinase (HK) enzyme activity ratio, and evaluate the erythrocyte PK (PK-R) protein level and erythrocyte metabolites as biomarkers for clinical severity. In this population not transfused for ≥90 days before sampling, the diagnostic sensitivity of the PK enzyme assay was 90% [95% confidence interval (CI) 77-97%], whereas the PK:HK ratio sensitivity was 98% (95% CI 87-100%). Read More

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http://dx.doi.org/10.1111/bjh.16724DOI Listing

Outcomes after progression of disease with anti-PD-1/PD-L1 therapy for patients with advanced melanoma.

Cancer 2020 May 28. Epub 2020 May 28.

Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

Background: Greater than one-half of patients with melanoma who are treated with antibodies blocking programmed cell death protein 1 receptor (anti-PD-1) experience disease progression. The objective of the current study was to identify prognostic factors and outcomes in patients with metastatic melanoma that progressed while they were receiving anti-PD-1 therapy.

Methods: The authors evaluated 383 consecutively treated patients who received anti-PD-1 for advanced melanoma between 2009 and 2019. Read More

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http://dx.doi.org/10.1002/cncr.32984DOI Listing

Anaphylaxis in pregnancy: a population-based multinational European study.

Anaesthesia 2020 May 28. Epub 2020 May 28.

National Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, UK.

Anaphylaxis in pregnancy is a rare but severe complication for both mother and infant. Population-based data on anaphylaxis in pregnancy are lacking from mainland European countries. This multinational study presents the incidence, causative agents, management and maternal and infant outcomes of anaphylaxis in pregnancy. Read More

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http://dx.doi.org/10.1111/anae.15069DOI Listing

Mediating Effect of Internet Addiction on the Relationship Between Individualism and Cyberbullying: Cross-Sectional Questionnaire Study.

J Med Internet Res 2020 May 28;22(5):e16210. Epub 2020 May 28.

College of Engineering and Technology, American University of the Middle East, Kuwait.

Background: Among a variety of dynamics that may have effects on internet-related behaviors, cultural orientation is particularly important. Previous studies suggest that individualism is a strong determinant of certain behaviors. In addition, findings suggest that vertical individualism may lead to the development of more tolerance for addiction and aggression on the internet. Read More

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http://dx.doi.org/10.2196/16210DOI Listing

Symptom and Disability Measurement by Common Foot and Ankle-Specific Outcome Rating Scales.

Foot Ankle Int 2020 May 28:1071100720920635. Epub 2020 May 28.

Southern California Orthopedic Institute, Van Nuys, CA, USA.

Background: Well-designed foot and ankle clinical outcomes research requires region-specific subjective outcome measures. Many foot and ankle-specific instruments are now available. Determining which instruments to choose is daunting. Read More

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http://dx.doi.org/10.1177/1071100720920635DOI Listing

Pain Anxiety Symptoms Scale-20: An empirical evaluation of measurement invariance across race/ethnicity, sex, and pain.

Psychol Assess 2020 May 28. Epub 2020 May 28.

Department of Psychology.

Pain-related anxiety, defined as fear of pain and pain-related sensations, is a transdiagnostic individual difference factor associated with pain-related problems, addictive disorders, and physical impairment among nonclinical and clinical populations. Pain-related anxiety is most commonly measured using the Pain Anxiety Symptoms Scale-20 (PASS-20). It was hypothesized that the data would provide evidence for a higher order PASS-20 factor structure and this structure would be invariant across race/ethnicity and sex. Read More

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http://dx.doi.org/10.1037/pas0000884DOI Listing

Don't get it twisted: Untangling the psychology of hair discrimination within Black communities.

Am J Orthopsychiatry 2020 May 28. Epub 2020 May 28.

Psychology Program.

Systems of oppression have shaped the prejudicial treatment of Black people based on the appearance of their hair, from the era of chattel enslavement to present-day America. Hair discrimination is a social injustice characterized by unfairly regulating and insulting people based on the appearance of their hair. A sampling of 90 African American community members narrated memories of hair discrimination using the guided hair autobiography method. Read More

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http://dx.doi.org/10.1037/ort0000468DOI Listing

The Banff 2019 Kidney Meeting Report (I): Updates on and clarification of criteria for T cell- and antibody-mediated rejection.

Am J Transplant 2020 May 28. Epub 2020 May 28.

Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Canada.

The XV. Banff conference for allograft pathology was held in conjunction with the annual meeting of the American Society for Histocompatibility and Immunogenetics in Pittsburgh, PA (USA) and focused on refining recent updates to the classification, advances from the Banff working groups, and standardization of molecular diagnostics. This report on kidney transplant pathology details clarifications and refinements to the criteria for chronic active (CA) T cell-mediated rejection (TCMR), borderline, and antibody-mediated rejection (ABMR). Read More

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http://dx.doi.org/10.1111/ajt.15898DOI Listing

A Snapshot of RTI Implementation a Decade Later: New Picture, Same Story.

J Learn Disabil 2020 May 28:22219420915867. Epub 2020 May 28.

University of North Carolina at Charlotte, USA.

Response to intervention (RTI) has evolved from its first decade of implementation. Because states guide and regulate policy and practice at the state and local education agency levels, it is important to understand their critical role in RTI implementation. A systematic review of all 50 state education agency websites was conducted to provide an updated "snapshot" of states' interpretation of RTI a decade after IDEA regulations were finalized. Read More

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http://dx.doi.org/10.1177/0022219420915867DOI Listing

Guidelines for primary health care-based telemental health in a low-to middle-income country: the case of Lebanon.

Int Rev Psychiatry 2020 May 28:1-9. Epub 2020 May 28.

Department of Psychiatry, Tufts University School of Medicine, Boston, MA, USA.

Significant efforts have been conducted to improve access to Mental Health Services (MHS) and reduce the burden of Mental Health Disorders (MHD) in Low-to Middle-Income Countries (LMIC). However, important challenges to accessing MHS still exist and limit improvements. Telemental Health (TMH), a modality that delivers remote MHS provides an ideal solution to complement existing efforts; however, there are limited reports on its implementation in developing countries such as Lebanon. Read More

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http://dx.doi.org/10.1080/09540261.2020.1766867DOI Listing

Chronic Obstructive Pulmonary Disease Prevalence and Associated Factors in a Setting of Well-Controlled HIV, A Cross-Sectional Study.

COPD 2020 May 28:1-9. Epub 2020 May 28.

Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, USA.

In Sub-Saharan Africa, COPD remains prevalent but its association with HIV is not well characterized especially in rural settings. We assessed for COPD prevalence, associated factors and lung function profile among HIV-infected individuals attending ART clinics in rural Nakaseke district of Uganda. We enrolled HIV-positive participants from four HIV treatment centers in rural Uganda. Read More

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http://dx.doi.org/10.1080/15412555.2020.1769583DOI Listing

Dyspnea in an HIV Patient: A Not so Typical Presentation of Lung Adenocarcinoma.

J Investig Med High Impact Case Rep 2020 Jan-Dec;8:2324709620927872

White River Health System, Batesville, AR, USA.

Dyspnea in a HIV patient often warrants an extensive workup. The most common etiology of this presentation is likely due to an infectious etiology. However, with the introduction of antiretroviral treatment, non-AIDS-defining illness including malignancies are increasingly being reported. Read More

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http://dx.doi.org/10.1177/2324709620927872DOI Listing

Alginate Sulfate Substrates Control Growth Factor Binding and Growth of Primary Neurons: Toward Engineered 3D Neural Networks.

Adv Biosyst 2020 May 27:e2000047. Epub 2020 May 27.

Biomedical Engineering Program, Maroun Semaan Faculty of Engineering and Architecture, American University of Beirut, Beirut, 1107 2020, Lebanon.

Sulfated glycosaminoglycans (sGAGs) are vital molecules of the extracellular matrix (ECM) of the nervous system known to regulate proliferation, migration, and differentiation of neurons mainly through binding relevant growth factors. Alginate sulfate (AlgSulf) mimics sGAGs and binds growth factors such as basic fibroblast growth factor (FGF-2). Here, thin films of biotinylated AlgSulf (b-AlgSulf ) are engineered with sulfation degrees (DS = 0. Read More

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http://dx.doi.org/10.1002/adbi.202000047DOI Listing

A Novel Method of Simultaneous In Situ Decompression of Lateral Calcaneal Bulge and Subtalar Arthrodesis Via a Single Incision for Malunion After Calcaneal Fractures.

Orthop Surg 2020 May 28. Epub 2020 May 28.

Department of Orthopaedic Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, China.

Objective: The aim of this study was to introduce a novel method of simultaneous in situ decompression of lateral calcaneal bulge and subtalar arthrodesis via a single incision for malunion after calcaneal fractures and evaluate the feasibility of this method.

Methods: From September 2010 to October 2011, six patients (five males and one female) with malunion and delayed heel pain after conservative treatment of displaced intra-articular calcaneal fractures were included in our study. The mean age of the six patients was 32. Read More

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http://dx.doi.org/10.1111/os.12686DOI Listing

Which Pre- and Postoperative Coronal Plane Laxity Parameters Influence Patient Satisfaction and Function after Primary Total Knee Arthroplasty?

J Knee Surg 2020 May 27. Epub 2020 May 27.

Queensland University of Technology Faculty of Science and Engineering, School of Biomedical Engineering, Brisbane, Queensland, Australia.

Soft tissue balancing, while accepted as crucial to total knee arthroplasty (TKA) outcomes, is incompletely defined as the subject of broad recommendations. We analyzed 120 computer-assisted, posterior stabilized TKA undertaken for osteoarthritis. Coronal plane laxity was measured, in the 91 varus and 29 valgus knees, prior to any bone resection or soft tissue release, and again after implant insertion. Read More

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http://dx.doi.org/10.1055/s-0040-1710362DOI Listing

Decomposing Race and Ethnic Differences in CVD Risk Factors for Mid-life Women.

J Racial Ethn Health Disparities 2020 May 27. Epub 2020 May 27.

General Preventative Medicine Resident, Preventive Medicine Residency Program, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street Room WB602, Baltimore, MD, 21205, USA.

Objective: This study decomposes race and ethnic differences in hypertension, waist circumference, obesity and allostatic load between black non-Hispanic (BNH), Mexican American (MA), and white non-Hispanic (WNH) women.

Data: This study uses 10,109 observations from The National Health and Nutrition Examination Survey from years 1999-2014 for BNH, MA women, and WNH between 40 and 75 years old.

Methodology: We used the Oaxaca-Blinder decomposition to explore how demographic, socioeconomic, healthcare access, and health behavior factors are associated with race and ethnic differences in blood pressure, waist circumference, body mass index (BMI), and allostatic load score (ALS). Read More

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http://dx.doi.org/10.1007/s40615-020-00769-9DOI Listing

A new species of Ameloblastella Kritsky, Mendoza-Franco & Scholz, 2000 (Monogenoidea: Dactylogyridae) from South American freshwater catfishes (Siluriformes: Pimelodidae).

Syst Parasitol 2020 May 27. Epub 2020 May 27.

Institute of Parasitology, Biology Centre of the Czech Academy of Sciences, and Faculty of Science, University of South Bohemia, Branišovská 31, 37005, České Budějovice, Czech Republic.

Ameloblastella martinae n. sp. is described from the gills of the pimelodid catfishes (Siluriformes: Pimelodidae) Sorubim lima (Bloch & Schneider) (type-host) and Hemisorubim platyrhynchos (Valenciennes) in the Peruvian Amazonia, and on Pseudoplatystoma corruscans (Spix & Agassiz) and P. Read More

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http://dx.doi.org/10.1007/s11230-020-09915-7DOI Listing

Preoperative Transfusion for Anemia in Patients Undergoing Abdominal Surgery for Malignancy.

J Gastrointest Surg 2020 May 27. Epub 2020 May 27.

Division of Endocrine and Oncologic Surgery, Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.

Background: Transfusion guidelines have been established for severe anemia, but limited data is available regarding the utility of preoperative transfusion. This study evaluates the predictive factors and relative value of preoperative transfusion in oncologic patients with moderate anemia undergoing abdominal surgery.

Methods: Using the American College of Surgeons National Surgical Quality Improvement Program database, adult patients with moderate anemia (hematocrit 21-27%) who underwent non-emergent abdominal oncologic resection from 2005 to 2017 were identified. Read More

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http://dx.doi.org/10.1007/s11605-020-04656-wDOI Listing

Infertility and assisted reproductive technology outcomes in Afro-Caribbean women.

J Assist Reprod Genet 2020 May 27. Epub 2020 May 27.

Division of Reproductive Endocrinology and Infertility, Women & Infants Hospital, 101 Dudley Fl 1, Providence, RI, 02905, USA.

Objective: To assess the causes of infertility and artificial reproductive technology (ART) outcomes in women of African descent living in the Caribbean and Bermuda.

Design: Cross-sectional study composed of a questionnaire administered to providers who care for women undergoing ART in the Caribbean and Bermuda.

Material And Methods: A questionnaire from the Deerfield Institute was adapted to meet the aims of our study with their permission. Read More

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http://dx.doi.org/10.1007/s10815-020-01826-2DOI Listing

Intracystic papillary carcinoma: clinical presentation, patterns of practice, and oncological outcomes.

Breast Cancer Res Treat 2020 May 28. Epub 2020 May 28.

Department of Surgery, American University of Beirut Medical Center (AUBMC), Phase 1 - Surgery Specialty Clinics - 4th Floor, Beirut, Lebanon.

Background: Intracystic/encapsulated papillary carcinoma remains a poorly understood disease of the breast with a little amount of reports that describe it. It shares features with DCIS and IDC and predominantly affects postmenopausal women. This study aims to evaluate the clinical presentation, treatment, and outcomes in IPC patients managed at our institution. Read More

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http://dx.doi.org/10.1007/s10549-020-05680-9DOI Listing

Morphological characters can strongly influence early animal relationships inferred from phylogenomic datasets.

Syst Biol 2020 May 27. Epub 2020 May 27.

Division of Invertebrate Zoology, American Museum of Natural History, New York.

There are considerable phylogenetic incongruencies between morphological and phylogenomic data for the deep evolution of animals. This has contributed to a heated debate over the earliest-branching lineage of the animal kingdom: The sister to all other Metazoa (SOM). Here we use published phylogenomic datasets (∼45,000-400,000 characters in size with ∼15-100 taxa) that focus on early metazoan phylogeny to evaluate the impact of incorporating morphological datasets (∼15-275 characters). Read More

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http://dx.doi.org/10.1093/sysbio/syaa038DOI Listing

Myocardial Infarction as the Initial Presentation for Fibromuscular Dysplasia.

Am J Med Case Rep 2020 12;8(7):166-172. Epub 2020 Apr 12.

Department of Internal Medicine, State University of New York: Downstate Medical Center, Brooklyn, New York, United States- 11203.

Background: Fibromuscular dysplasia (FMD) is a non-atherosclerotic disease that affects medium-sized arteries and results in stenosis, dissection, aneurysm or occlusion. It is most commonly reported in the renal and carotid arteries. Involvement of coronary arteries is quite rare and and leads to serious consequences. Read More

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