396,564 results match your criteria American Biology Teacher[Journal]


Myocardial extracellular volume fraction quantitation using cardiac dual-energy CT with late iodine enhancement in patients with heart failure without coronary artery disease: A single-center prospective study.

Eur J Radiol 2021 May 1;140:109743. Epub 2021 May 1.

Department of Radiology, First Affiliated Hospital of Soochow University, Shizi Street No.188, Suzhou, 215002, China; Institute of Medical Imaging, Soochow University, Shizi Street No.188, Suzhou, 215002, China. Electronic address:

Purpose: To evaluate the relationship between myocardial extracellular volume (ECV) fraction measured using dual-energy computed tomography with late iodine enhancement (LIE-DECT) and risk of heart failure (HF) in patients without coronary artery disease (CAD), and to evaluate the relationship between ECV and left ventricular structure and function.

Materials And Methods: Sixty consecutive HF patients without CAD and 60 consecutive participants without heart disease who underwent coronary CT angiography (CCTA) following LIE-DECT were included. ECV of the left ventricle was calculated from the iodine maps and hematocrit levels using the American Heart Association (AHA) 16-segment model. Read More

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Longer Operative Time Associated with Prolonged Length of Stay, Non-Home Discharge and Transfusion Requirement after Anterior Cervical Discectomy and Fusion: an Analysis of 24,593 Cases.

Spine J 2021 May 7. Epub 2021 May 7.

Department of Orthopaedic Surgery, Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH, USA; Center for Spine Health, Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH, USA.

Background: Prolonged operative time of single-level ACDF has been associated with adverse postoperative outcomes. The current literature does not contain a comprehensive quantitative description of these associations PURPOSE: This study characterized the associations between single-level anterior cervical discectomy and fusion(ACDF) operative time and 1)30-day postoperative healthcare utilization, and 2)the incidence of local wound complications, need for transfusion and mechanical ventilation.

Design/setting: Retrospective database analysis PATIENT SAMPLE: The American College of Surgeons National Surgical Quality Improvement Program(ACS-NSQIP) database was queried for single-level ACDF cases(2012-2018) using current procedural terminology codes. Read More

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eGFR Variability in Patients with Heart Failure and Chronic Kidney Disease.

J Card Fail 2021 May 7. Epub 2021 May 7.

Department of Medicine, Duke University School of Medicine, Durham, NC; Duke Clinical Research Institute, Durham, NC. Electronic address:

Background: Greater variability in estimated glomerular filtration rate (eGFR) is associated with higher mortality in patients with chronic kidney disease (CKD). Heart failure (HF) is common in CKD and may increase variability through changes in hemodynamic and volume regulation. We sought to determine if patients with versus without HF have higher kidney function variability in CKD, and to define the association with mortality. Read More

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COMPARISON OF MICROSCOPIC HEMATURIA GUIDELINES AS APPLIED IN 1,018 PATIENTS WITH MICROSCOPIC HEMATURIA.

Urology 2021 May 7. Epub 2021 May 7.

Ankara University Faculty of Medicine, UROLOGY Department. Electronic address:

Objective: To compare the 2012 American Urological Association (AUA) and 2020 AUA/Society of Urodynamics, Female Pelvic Medicine & Urogenital Reconstruction (SUFU) microscopic hematuria (MH) guidelines as applied in 1,018 patients with MH, to confirm of risk groups and to investigate the natural history of patients with MH.

Materials And Methods: Patients who had undergone a complete urological evaluation for MH according to the 2012 AUA MH guidelines were identified retrospectively. All the patients were then classified into low-, intermediate-, or high-risk for urinary tract malignancy according to the updated 2020 AUA/SUFU MH guidelines, for a second evaluation. Read More

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Levels and trends in Chagas disease-related mortality in Brazil, 2000-2019.

Acta Trop 2021 May 7:105948. Epub 2021 May 7.

Institute of Studies in Public Health, Federal University of Rio de Janeiro, Avenida Horácio Macedo, S/N, Ilha do Fundão - Cidade Universitária, 21941-598 Rio de Janeiro, Rio deJaneiro, Brazil; Department of Epidemiology, Social Medicine Institute, State University of Rio de Janeiro, Rua São Francisco Xavier 524, Maracanã, 20550-013 Rio de Janeiro, Rio de Janeiro, Brazil.

Chagas disease remains an important public health problem with high morbidity and mortality in several Latin American countries. This nationwide population-based ecological study analyzes the epidemiological characteristics and time trends of Chagas disease-related mortality in Brazil, 2000-2019. We included all deaths reported in Brazil in which Chagas disease was mentioned in the death certificate either as an underlying or associated cause of death (multiple causes of death). Read More

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Efficacy and safety of voclosporin versus placebo for lupus nephritis (AURORA 1): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial.

Lancet 2021 May 7. Epub 2021 May 7.

Research, Aurinia Pharmaceuticals, Victoria, BC, Canada. Electronic address:

Background: Voclosporin, a novel calcineurin inhibitor approved for the treatment of adults with lupus nephritis, improved complete renal response rates in patients with lupus nephritis in a phase 2 trial. This study aimed to evaluate the efficacy and safety of voclosporin for the treatment of lupus nephritis.

Methods: This multicentre, double-blind, randomised phase 3 trial was done in 142 hospitals and clinics across 27 countries. Read More

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The State of Portuguese-American Health Disparities.

Acta Med Port 2021 Mar 1;34(3):171-172. Epub 2021 Mar 1.

Georgia State University. Atlanta. Georgia. United States.

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Ancient horse genomes reveal the timing and extent of dispersals across the Bering Land Bridge.

Mol Ecol 2021 May 10. Epub 2021 May 10.

Biomolecular Engineering, University Of California Santa Cruz, Santa Cruz, United States.

The Bering Land Bridge (BLB) last connected Eurasia and North America during the Late Pleistocene. Although the BLB would have enabled transfers of terrestrial biota in both directions, it also acted as an ecological filter whose permeability varied considerably over time. Here we explore the possible impacts of this ecological corridor on genetic diversity within, and connectivity among, populations of a once wide-ranging group, the caballine horses (Equus spp. Read More

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Treatments for unruptured intracranial aneurysms.

Cochrane Database Syst Rev 2021 May 10;5:CD013312. Epub 2021 May 10.

Department of Surgery, Division of Vascular and Endovascular Surgery, Universidade Federal de São Paulo, São Paulo, Brazil.

Background: Unruptured intracranial aneurysms are relatively common lesions in the general population, with a prevalence of 3.2%, and are being diagnosed with greater frequency as non-invasive techniques for imaging of intracranial vessels have become increasingly available and used. If not treated, an intracranial aneurysm can be catastrophic. Read More

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Emotion dysregulation moderates the relationship between alcohol use and eating pathology among heavy-drinking college men.

J Clin Psychol 2021 May 10. Epub 2021 May 10.

Department of Psychology, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA.

Objectives: There is limited research examining the relationship between alcohol use and eating pathology in men or factors that may moderate this association. The current study investigated the relationship between alcohol use and eating pathology, and examined emotion dysregulation as a moderator of this association, among heavy-drinking college men.

Method: Men mandated to receive an alcohol intervention (N = 88; average age = 19 years) completed questionnaires related to alcohol use, emotion dysregulation, and eating pathology. Read More

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Morphological and Molecular Data Reveal Two New Species of Viannaia (Nematoda: Viannaiidae), Parasitizing Opossums (Mammalia: Didelphidae) in Mexico.

J Parasitol 2021 May;107(3):388-403

Departamento de Biología Evolutiva, Facultad de Ciencias, Universidad Nacional Autónoma de México. Avenida Universidad 3000, Ciudad Universitaria, C. P. 04510, Mexico City, Mexico.

Two new species of Viannaia from the intestine of the North American opossums, Didelphis virginiana (Virginia opossum), and Philander opossum (gray four-eyed opossum), are described based on morphological and molecular data, through an integrative taxonomic approach. Maximum likelihood and Bayesian inference analyses for each dataset and the concatenated dataset were performed using a mitochondrial cytochrome c oxidase subunit 1 (COI) gene, and the nuclear ribosomal internal transcribed spacer region (ITS1-5.8S-ITS2). Read More

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Self-reported medication adherence among patients with diabetes or hypertension, Médecins Sans Frontières Shatila refugee camp, Beirut, Lebanon: A mixed-methods study.

PLoS One 2021 10;16(5):e0251316. Epub 2021 May 10.

Department of Global Health, University of Washington, Seattle, Washington, United States of America.

Introduction: Low adherence to medications, specifically in patients with Diabetes (DM) and Hypertension (HTN), and more so in refugee settings, remains a major challenge to achieving optimum clinical control in these patients. We aimed at determining the self-reported medication adherence prevalence and its predictors and exploring reasons for low adherence among these patients.

Methods: A mixed-methods study was conducted at Médecins Sans Frontières non-communicable diseases primary care center in the Shatila refugee camp in Beirut, Lebanon in October 2018. Read More

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Comprehensive approach to HIV/AIDS testing and linkage to treatment among men who have sex with men in Curitiba, Brazil.

PLoS One 2021 10;16(5):e0249877. Epub 2021 May 10.

Division of Global HIV and TB (DGHT), Centers for Disease Control and Prevention (CDC), Country Office in Brasília, Brasília, Brazil.

Introduction: The Curitiba (Brazil)-based Project, A Hora é Agora (AHA), evaluated a comprehensive HIV control strategy among men who have sex with men (MSM) aimed at expanding access to HIV rapid testing and linking HIV-positive MSM to health services and treatment. AHA's approach included rapid HIV Testing Services (HTC) in one mobile testing unit (MTU); a local, gay-led, non-governmental organization (NGO); an existing government-run health facility (COA); and Internet-based HIV self-testing. The objectives of the paper were to compare a) number of MSM tested in each strategy, its positivity and linkage; b) social, demographic and behavioral characteristics of MSM accessing the different HTC and linkage services; and c) the costs of the individual strategies to diagnose and link MSM to services. Read More

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Breeding and hibernation of captive meadow jumping mice (Zapus hudsonius).

PLoS One 2021 10;16(5):e0240706. Epub 2021 May 10.

Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.

Hibernating mammals exhibit unique metabolic and physiological phenotypes that have potential applications in medicine or spaceflight, yet our understanding of the genetic basis and molecular mechanisms of hibernation is limited. The meadow jumping mouse, a small North American hibernator, exhibits traits-including a short generation time-that would facilitate genetic approaches to hibernation research. Here we report the collection, captive breeding, and laboratory hibernation of meadow jumping mice. Read More

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Seasonal Influenza Prevention and Control Progress in Latin America and the Caribbean in the Context of the Global Influenza Strategy and the COVID-19 Pandemic.

Am J Trop Med Hyg 2021 May 10. Epub 2021 May 10.

4Center for Global Health, Colorado School of Public Health, Aurora, Colorado.

Each year in Latin America and the Caribbean, seasonal influenza is associated with an estimated 36,500 respiratory deaths and 400,000 hospitalizations. Since the 2009 influenza A(H1N1) pandemic, the Region has made significant advances in the prevention and control of seasonal influenza, including improved surveillance systems, burden estimates, and vaccination of at-risk groups. The Global Influenza Strategy 2019-2030 provides a framework to strengthen these advances. Read More

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Case Report: Acute Kidney Failure due to Massive Envenomation of a Two-Year-Old Child Caused by Killer Bee Stings.

Am J Trop Med Hyg 2021 May 10. Epub 2021 May 10.

1Service de Médecine et Chirurgie Pédiatrique, Cayenne Hospital, Cayenne, French Guiana.

A hybrid species of Brazilian bee has proliferated on the South American continent since 1956. We describe a "killer bee" swarm attack on a 2-year-old girl in French Guiana. The patient weighed 10 kg, and approximately hundreds of bees' stingers were removed, that is, 10 stings/kg. Read More

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Proactive Consultation-Liaison Psychiatry: American Psychiatric Association Resource Document.

J Acad Consult Liaison Psychiatry 2021 Mar-Apr;62(2):169-185. Epub 2021 Jan 29.

Department of Psychiatry, Centre for Addiction and Mental Health, University of Toronto, Toronto, ON.

In 2019, the American Psychiatric Association Council on Consultation-Liaison (C-L) Psychiatry convened a work group to develop a resource document on proactive C-L psychiatry. A draft of this document was reviewed by the Council in July 2020, and a revised version was approved by this Council in September 2020. The accepted version was subsequently reviewed by the American Psychiatric Association Council on Health Care Systems and Financing in November 2020. Read More

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January 2021

The health economic impact of varying levels of adherence to colorectal screening on providers and payers.

J Med Econ 2021 Jan-Dec;24(1):69-78

Exact Sciences Corporation, Madison, WI, USA.

Aims: To examine the impact of increasing multi-target stool DNA test (mt-sDNA [Cologuard]) utilization for colorectal cancer (CRC) screening in cohorts aged 50-75 and 45-75 years old with varying levels of adherence from the perspectives of integrated delivery networks (IDNs) and payers.

Materials And Methods: We developed a budget impact model that simulates CRC screening with colonoscopy over a 10-year time horizon, fecal immunochemical test (FIT), and mt-sDNA according to the United States Preventive Services Task Force and American Cancer Society guidelines for average risk adults. We evaluated varying levels of screening adherence for a status quo scenario and for an increased mt-sDNA utilization scenario, from the IDN and payer perspectives. Read More

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Accessing Targeted Therapies: A Potential Roadblock to Implementing Precision Oncology?

JCO Oncol Pract 2021 May 10:OP2000927. Epub 2021 May 10.

Division on Hematology and Oncology, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX.

Purpose: Advances in genomic techniques have led to increased use of next-generation sequencing (NGS). We evaluated the extent to which these tests guide treatment decisions.

Methods: We developed and distributed a survey assessing NGS use and outcomes to a survey pool of ASCO members. Read More

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Parenting behaviors of mothers with posttraumatic stress: The roles of cortisol reactivity and negative emotion.

J Fam Psychol 2021 May 10. Epub 2021 May 10.

Although posttraumatic stress disorder (PTSD) is associated with negative family outcomes, including parenting challenges, little is known about the biological and emotional processes that might underlie this association. The present project addressed this gap by examining associations between maternal PTSD and parenting behaviors in a lab setting. We expected that PTSD would be associated with more ineffective parenting behaviors and that negative emotion and cortisol reactivity would mediate this relation. Read More

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Diabetes: Pharmacotherapy for Type 2 Diabetes.

Authors:
Erin St Onge

FP Essent 2021 May;504:22-27

University of Florida College of Pharmacy Department of Pharmacotherapy and Translational Research, 1225 Center Drive, Gainesville, FL 32610.

For most patients with type 2 diabetes, the American Diabetes Association (ADA) recommends an A1c goal of less than 7%. However, this goal may be adjusted depending on certain patient factors. Metformin should be used as a first-line treatment in all patients with type 2 diabetes unless contraindicated. Read More

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Diabetes: Screening, Diagnosis, and Prevention of Type 2 Diabetes.

Authors:
Ernestine Lee

FP Essent 2021 May;504:16-21

University of Texas at Austin Dell Medical School Department of Population Health, 1601 Trinity St. Bldg. B Stop Z0500, Austin, TX 78712.

From 2013-2016, 34.5% of US adults had prediabetes. The U. Read More

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Diabetes: Type 1 Diabetes.

FP Essent 2021 May;504:11-15

University of Texas at Austin Dell Medical School Department of Population Health, 1601 Trinity St. Bldg. B Stop Z0500, Austin, TX 78712.

Type 1 diabetes is defined as a state of hyperglycemia due to insulin deficiency caused by autoimmune pancreatic beta-cell destruction. The risk among individuals in the general population has been estimated at 0.5%. Read More

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Incidence, Outcomes, and Prediction of Postoperative Urinary Retention After a Nonurologic Procedure.

J Am Acad Orthop Surg Glob Res Rev 2020 May;4(5):e1900149

From the Department of Urology (Dr. Abdul-Muhsin, Jakob, Dr. Navaratnam, Dr. Khan, and Dr. Humphreys), Department of Research Biostatistics (Dr. Cha and Dr. Zhang), and the Department of Orthopedic Surgery (Dr. Schwartz), Mayo Clinic Arizona, Phoenix, AZ.

Purpose: To develop a prognostic model to estimate postoperative urinary retention (POUR) after lower limb arthroplasty.

Methods: One thousand two hundred twenty patients underwent 1,374 joint replacement operations (812 knees and 562 hips) between December 2008 and May 2014. Detailed variables were collected. Read More

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Subscapularis Function After Total Shoulder Arthroplasty Using Lesser Tuberosity Osteotomy or Tenotomy.

J Am Acad Orthop Surg Glob Res Rev 2020 May;4(5):e2000032

From Avera Medical Group Orthopedics and Sports Medicine, Sioux Falls, SD (Dr. O'Brien); Llanerch Orthopaedics, Havertown, PA (Dr. Kazanjian); San Francisco Shoulder Elbow and Hand Clinic, San Francisco, CA (Dr. Kell); and Mississippi Sports Medicine and Orthopaedic Center, Jackson, MS (Dr. Hobgood).

Introduction: Subscapularis dysfunction is a recognized complication after total shoulder arthroplasty (TSA). However, optimal subscapularis management during TSA is controversial. Subscapularis tenotomy (ST) has been used, whereas lesser tuberosity osteotomy (LTO) has gained popularity. Read More

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North American Contact Dermatitis Group Patch Test Results: 2017-2018.

Dermatitis 2021 Mar-Apr 01;32(2):111-123

Division of Dermatology, University of Louisville, KY.

Background: Patch testing is an important diagnostic tool for assessment of allergic contact dermatitis (ACD).

Objective: This study documented the North American Contact Dermatitis Group (NACDG) patch testing results from March 1, 2017, to December 31, 2018.

Methods: At 14 centers in North America, patients with dermatitis were tested in a standardized manner with a screening series of 70 allergens and supplemental allergens as clinically indicated. Read More

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Pathfinders in oncology from the time the causal relation between tobacco use and lung cancer was established to publication of the first Cancer Staging Manual by the American Joint Committee on Cancer.

Authors:
Steven I Hajdu

Cancer 2021 May 10. Epub 2021 May 10.

Pathology Consultants, Westlake Village, California.

During the period from 1962 to 1977, several antigens, notably carcinoembryonic antigen and prostate-specific antigen, were discovered and entered clinical use. Ultrasonography, positron emission tomography scanning, and magnetic resonance imaging were introduced, and adjuvant radiation and chemotherapy after limited surgery became routine procedures. Radioimmunoassay and immunohistochemistry techniques were standardized. Read More

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