16,991 results match your criteria Amenorrhea Primary


Postpartum family-planning barriers and catalysts in Burkina Faso and the Democratic Republic of Congo: a multiperspective study.

Open Access J Contracept 2018 9;9:63-74. Epub 2018 Nov 9.

Institut de Recherche en Sciences de la Santé, Ouagadougou, Burkina Faso.

Purpose: To address the high unmet need for postpartum family planning (PPFP) in resource-limited settings, particularly in sub-Saharan Africa, this study aimed to identify PPFP-related barriers and catalysts to inform policies and programs to increase access to postpartum contraception.

Methods: Using qualitative methodology, we explored the perspectives of women, adolescent girls, men, religious and community leaders, service providers, and decision makers from three rural communities in Burkina Faso and three rural-urban communities in the Democratic Republic of Congo. Both countries have high unmet need for PPFP and are priority countries of the French Muskoka Fund for Maternal and Child Health. Read More

View Article
November 2018

An Outbreak of in a Moroccan Neonatal Intensive Care Unit.

Adv Med 2018 1;2018:4867134. Epub 2018 Nov 1.

Neonatal Intensive Care Unit, Mother-Child Center, Mohammed VI University Medical Hospital of Marrakesh, Morocco.

() is an microorganism that is widespread in the environment, which may be the source of nosocomial infections, rare in the newborn but severe, and often in the form of outbreaks. The aim of our study is to report our experience, during an outbreak of , to show the severity of this germ, with review of the literature. Our study was retrospective, including 8 newborns with nosocomial infection, collected in the neonatal intensive care unit of Mohammed VI University Medical Hospital, during the epidemic period, over a period of 2 months (July and August 2016). Read More

View Article
November 2018
1 Read

1,25 Dihydroxyvitamin D3 Enhances the Antifibroid Effects of Ulipristal Acetate in Human Uterine Fibroids.

Reprod Sci 2018 Dec 4:1933719118812720. Epub 2018 Dec 4.

1 Department of Obstetrics and Gynecology, University of Illinois at Chicago, Chicago, IL, USA.

Background:: Both European and American trials showed superior effect of ulipristal acetate (UPA) to placebo. However, the latter, which included black patients with known higher vitaminD3 deficiency risk, showed lower rate of amenorrhea responders and insignificant uterine fibroid (UF) size reduction. Our objective is to investigate whether adding vitamin D to UPA can enhance UPA potency on UF phenotype in vitro. Read More

View Article
December 2018
1 Read

Complications somatiques de l’anorexie mentale. Elles sont responsables d’une mortalité élevée.

Rev Prat 2016 Feb;66(2):153-157

Clinique des maladies mentales et de l'encéphale, hôpital Sainte-Anne, Paris, France.

Medical complications of anorexia nervosa. Anorexia nervosa causes acute or chronic medical complications that can affect most organs: dermatologic complications, gastrointestinal complications (including constipation, delayed gastric emptying, rarely hepatitis), endocrine and bone (amenorrhea, infertility, hypoglycemia, delayed puberty, arrested growth, osteoporosis.. Read More

View Article
February 2016
1 Read

Management of placental site trophoblastic tumor: Two case reports.

Medicine (Baltimore) 2018 Nov;97(48):e13439

Interdisciplinary Department of Medicine, Gynecology and Obstetrics Clinic, University of Bari.

Rationale: Placental site trophoblastic tumor (PSTT) is a very rare malignant tumor, belonging to a family of pregnancy-related illnesses, called gestational trophoblastic diseases (GTD). Less than 300 cases of PSTT have been reported in literature, with an incidence of ≈ 1/50,000-100,000 pregnancies representing only 0.23% to 3. Read More

View Article
November 2018
2 Reads

Cases of Amenorrhœa, Treated with the Ammoniated Tincture of Guaiacum.

Authors:
George Jewel

Lond Med Phys J 1826 Dec;1(6):543-545

Surgeon to the Middlesex Infirmary.

View Article
December 1826

Observations on Amenorrhœa.

Authors:
J Mahon

Lond Med Phys J 1818 Nov;40(237):381-386

View Article
November 1818

Fatal ruptured ectopic pregnancy - a case report.

Med Leg J 2018 Nov 29:25817218795337. Epub 2018 Nov 29.

Department of Forensic Medicine, M.S. Ramaiah Medical College, Bangalore, India.

A 26-year-old unmarried female with a history of acute abdominal pain and bleeding per vagina was brought unresponsive to the hospital. She was in shock on arrival and could not be resuscitated. Death was registered as a medico-legal case. Read More

View Article
November 2018
1 Read

Weight restoration in atypical anorexia nervosa: A clinical conundrum.

Int J Eat Disord 2018 Nov 28. Epub 2018 Nov 28.

Division of Adolescent and Young Adult Medicine, Department of Pediatrics, University of California, San Francisco, California.

The determination of the treatment goal weight for adolescents with a restrictive eating disorder (ED) and a prior history of obesity, such as in atypical anorexia nervosa (AAN), represents an ongoing challenge for clinicians. This determination is particularly complex given competing interests of physical recovery from significant weight loss, mental recovery from ED psychopathology, and the medical comorbidities associated with obesity. We report the case of a 15-year old female with a history of obesity and irregular periods who presented with significant weight loss and absence of menses for 3 months. Read More

View Article
November 2018
1 Read

Autism is a prenatal disorder: Evidence from late gestation brain overgrowth.

Autism Res 2018 Dec 28;11(12):1635-1642. Epub 2018 Nov 28.

UMR 1253, iBrain, Université de Tours, Inserm, Tours, France.

This retrospective study aimed to specify the critical period for atypical brain development in individuals with autism spectrum disorder (ASD) using prenatal and postnatal head growth parameters. The sample consisted of 80 Caucasian, unrelated, idiopathic patients with ASD born after 1995. Fetal ultrasound parameters (head circumference [HC], abdominal circumference, and femur length) were obtained during the second and third trimesters of gestation. Read More

View Article
December 2018
2 Reads

Prevalence of Stress Urinary Incontinence in Women with Premature Ovarian Insufficiency.

J Womens Health (Larchmt) 2018 Nov 28. Epub 2018 Nov 28.

State Key Laboratory of Reproductive Medicine, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Nanjing Medical University/Jiangsu Province Hospital, Nanjing Medical University , Nanjing, China .

Background: To determine the prevalence of stress urinary incontinence (SUI) and associated factors in women with premature ovarian insufficiency (POI).

Materials And Methods: The study included 149 patients with POI and 303 control women without POI. Age, body mass index (BMI), gestational history, time since onset of POI, and status of hormone therapy (HT) for POI were recorded. Read More

View Article
November 2018
3 Reads

Bromocriptine-responsive supersellar germinoma with the expression of dopamine receptors: A case report.

Clin Neurol Neurosurg 2018 Nov 10;176:15-18. Epub 2018 Nov 10.

Department of Neurosurgery, Center of Pituitary Tumor, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197# Ruijin Er Road, Shanghai, 200025, China. Electronic address:

Background: Germinomas are sensitive to radiotherapy and chemotherapy. However, there has been no report involving in the potential therapeutic effect of dopamine agonists (DAs) such as bromocriptine on germinomas.

Case Description: A 20-year-old female was presented with bitemporal visual disturbance and amenorrhea. Read More

View Article
November 2018
3 Reads

Impact of Route of Estrogen Administration on Bone Turnover Markers in Oligoamenorrheic Athletes and its Mediators.

J Clin Endocrinol Metab 2018 Nov 23. Epub 2018 Nov 23.

Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School.

Objective: Transdermal, but not oral, estrogen replacement improves bone mineral density (BMD) in athletes with oligo-amenorrhea (OA). Our objective was to determine mechanisms that may explain the impact of route of estrogen administration on bone outcomes.

Methods: 73 OA between 14-25 years old received (i) a 17β-estradiol transdermal patch continuously with cyclic oral micronized progesterone (PATCH), (ii) a combined ethinyl estradiol and desogestrel pill (PILL), or (iii) no estrogen/progesterone (NONE) for 12-months. Read More

View Article
November 2018
5 Reads

Similarities and differences in the reproductive phenotypes of women with congenital hypogonadotrophic hypogonadism caused by GNRHR mutations and women with polycystic ovary syndrome.

Hum Reprod 2018 Nov 24. Epub 2018 Nov 24.

University of Paris-Sud and University Paris-Saclay, Le Kremlin-Bicêtre, France.

Study Question: Does the phenotype of women with normosmic congenital hypogonadotrophic hypogonadism (nCHH) and pituitary resistance to GnRH caused by biallelic mutations in the GnRH receptor (GNRHR) (nCHH/bi-GNRHR) differ from that of women with polycystic ovary syndrome (PCOS)?

Summary Answer: Women with nCHH/bi-GNRHR have variable pubertal development but nearly all have primary amenorrhea and an exaggerated LH response to GnRH stimulation, similar to that seen in women with PCOS.

What Is Known Already: Women with nCHH/bi-GNRHR are very rare and their phenotype at diagnosis is not always adequately documented. The results of gonadotrophin stimulation by acute GnRH challenge test and ovarian features have not been directly compared between these patients and women with PCOS. Read More

View Article
November 2018
6 Reads

Bi-allelic recessive loss-of-function mutations in FIGLA cause premature ovarian insufficiency with short stature.

Clin Genet 2018 Nov 25. Epub 2018 Nov 25.

IVF Center, Department of Obstetrics and Gynecology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.

Premature ovarian insufficiency (POI) is a group of heterogeneous disorders characterized by decreased ovarian reserve and increased follicle stimulating hormone (FSH) levels. It is rarely associated with short stature. FIGLA mutations with POI are identified with regards to heterozygosity; till date, only one affected family has been identified with homozygous mutations in FIGLA but without functional evaluation. Read More

View Article
November 2018
1 Read

Vesicouterine Fistula (VUF) as a Rare Urogenital Complication Managed with Delayed Surgical Repair: A Case Report and Review of the Literature.

Case Rep Obstet Gynecol 2018 24;2018:2394896. Epub 2018 Oct 24.

Department of Urology, 424 General Military Hospital of Thessaloniki, Thessaloniki, Greece.

Vesicouterine fistula (VUF) represents a rare urogenital complication. It is considered to be the least common type of urogenital fistulas. Iatrogenic reasons have been shown to be the most prominent cause, with lower segment caesarean section accounting for approximately two-thirds of the cases. Read More

View Article
October 2018
6 Reads

Müllerian aplasia with severe hematometra: A case report of diagnosis and management in a low resource setting.

J Pediatr Adolesc Gynecol 2018 Nov 21. Epub 2018 Nov 21.

Department of Obstetrics and Gynecology University of Iowa Carver College of Medicine 200 Hawkins Dr. Iowa City, IA 52241.

Background: Müllerian aplasia or Mayer-Rokitansky-Küster-Hauser syndrome is described as congenital absence of the proximal vagina with or without absence of the cervix and uterus, most often recognized following the onset of primary amenorrhea.

Case: An 18-year-old female presented to a free medical clinic in Arcahaie, Haiti with primary amenorrhea, abdominal distention and cyclic monthly abdominal pain. Physical exam was significant for uterus palpable superior to the umbilicus, absence of vagina, and rectal exam without palpable vagina or cervix. Read More

View Article
November 2018
3 Reads

Iron status at opposite ends of the menstrual function spectrum.

J Trace Elem Med Biol 2019 Jan 19;51:169-175. Epub 2018 Oct 19.

The Women's Health and Exercise Laboratory, The Pennsylvania State University, 104 Noll Laboratory, University Park, PA 16802, United States. Electronic address:

Objectives: Although exercising women are at high risk of poor iron status, it is unknown how non-pathological, physiological menstrual function affects iron status. As such, this study investigates the association between menstrual function and iron status in exercising women with amenorrhea and exercising women with ovulatory, eumenorrheic menstrual cycles.

Design: Cross-sectional analysis of iron depletion prevalence, iron status indices, exercise parameters, and diet composition. Read More

View Article
January 2019
3 Reads

Female Pseudo Hermaphroditism: Late Onset Congenital Adrenal Hyperplasia.

J Ayub Med Coll Abbottabad 2018 Jul-Sep;30(3):458-462

Department of Obstetrics and Gynaecology, Foundation University Medical College /Fauji Foundation Hospital Rawalpindi, Pakistan.

Non-classic congenital adrenal hyperplasia is a genetic condition caused by deficiency of 21- hydroxylase deficiency (NCAH). It is a milder and later onset form of a genetic condition known as congenital adrenal hyperplasia. We present four cases of non-classical congenital adrenal hyperplasia presented in gynae OPD foundation university medical college Fauji foundation hospital from Jan 2016 to March 2017. Read More

View Article
November 2018
5 Reads

Long-term outcome of trans-sphenoidal surgery for Cushing's disease in Indian patients.

Acta Neurochir (Wien) 2018 Nov 21. Epub 2018 Nov 21.

Departments of Endocrinology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.

Background: The results of trans-sphenoidal surgery (TSS) in Cushing's disease (CD) vary widely depending upon patient characteristics as well as surgical experience. Patients in India are often referred late to referral centers. We studied the rates of remission and endocrine deficiencies after TSS in patients with CD presenting to a referral hospital in India. Read More

View Article
November 2018
7 Reads

Valproate-Induced Polycystic Ovary Syndrome in a Girl with Epilepsy: A Case Study.

J Nippon Med Sch 2018 ;85(5):287-290

Department of Pediatrics, Nippon Medical School Tama Nagayama Hospital.

Background: Polycystic ovary syndrome (PCOS) is a common ovulatory disorder that can be induced by sodium valproate (VPA).

Patient: We report a case of PCOS that developed in a 15-year-old girl with idiopathic epilepsy after she took VPA. VPA administration stopped her seizures, but it also led to weight gain and amenorrhea, and the patient was diagnosed with PCOS on the basis of diagnostic imaging and serological examination results. Read More

View Article
January 2018
4 Reads

[Splenic infarction revealing infectious endocarditis in a pregnant woman: about a case and brief literature review].

Pan Afr Med J 2018 27;30:184. Epub 2018 Jun 27.

Service de Gynécologie-Obstétrique, Hôpital Militaire d'Instruction, Rabat, Maroc.

The diagnosis of splenic infarction is rarely reported in pregnant women. Current incidence of splenic infarction, especially during infectious endocardites as well as diagnostic methods used are poorly specified in the literature. We here report the case of a 26-year old woman with no particular previous history or cardiovascular risk factor who, at the end 14 weeks of amenorrhea, presented to the Emergency Department with febrile syndrome evolving over 10 days and abdominal pain of recent onset at the level of the left hypochondre. Read More

View Article
June 2018
2 Reads

Testing a proof of concept model for group couples counseling in family planning in Northern Uganda.

Pan Afr Med J 2018 27;30:179. Epub 2018 Jun 27.

Institute for Reproductive Health (IRH), Georgetown University, Washington DC, USA.

Introduction: The post-conflict Acholi sub-region of Uganda is undergoing a period of transition that is influencing access, acceptability and use of family planning (FP). Low FP use and high unmet need for FP in Uganda's northern region provides a unique opportunity to test a community-based group counseling approach to reduce unintended pregnancies among young couples. We share findings from a proof of concept testing model in delivering fertility awareness methods (FAM) to groups of couples by trained non-health community youth agents. Read More

View Article

Amenorrhea along with renal and thyroid metastasis: Unusual presentation of pancreatic adenocarcinoma.

Med J Armed Forces India 2018 Oct 28;74(4):400-403. Epub 2017 Nov 28.

MG Med, HQ MB Area, Jabalpur, India.

View Article
October 2018

New mutation causing androgen insensitivity syndrome - a case report and review of literature.

Gynecol Endocrinol 2018 Nov 19:1-4. Epub 2018 Nov 19.

d Department of Reproductive Biology and Stem Cells , Institute of Human Genetics, Polish Academy of Sciences , Poznan , Poland.

Androgen insensitivity syndrome (AIS) is a congenital disorder in which a defect in the androgen receptor (AR) gene leads to cellular resistance to androgens. Defects in the AR gene, located on the X chromosome, result in the development of a feminine phenotype in chromosomally male (46, XY) individuals. In this case report, we present a 44 years old patient with complete androgen insensitivity syndrome (CAIS) initially presenting with primary amenorrhea. Read More

View Article
November 2018
3 Reads

Impact of Chemotherapy-induced Menopause in Women of Childbearing Age With Non-metastatic Breast Cancer - Preliminary Results From the MENOCOR Study.

Clin Breast Cancer 2018 Oct 23. Epub 2018 Oct 23.

Université Clermont Auvergne, Centre Jean Perrin, INSERM, U1240 Imagerie Moléculaire et Stratégies Théranostiques, Clermont-Ferrand, France.

Background: Young patients with breast cancer treated with chemotherapy can experience ovarian failure, which can lead to chemotherapy-induced menopause (CIM) impacting the quality of life (QoL). A prospective study was set out to evaluate the impact of CIM on QoL in women of childbearing age with non-metastatic breast cancer, and this article reports results of the interim analysis conducted to evaluate feasibility and to see preliminary results.

Patients And Methods: A total of 58 women (age, 18-46 years) with newly diagnosed breast cancer and treated with chemotherapy were eligible. Read More

View Article
October 2018
3 Reads

Self-reported Polycystic Ovary Syndrome is Associated with Hypertension: A Northern Finland Birth Cohort 1966 Study.

J Clin Endocrinol Metab 2018 Nov 15. Epub 2018 Nov 15.

Department of Obstetrics and Gynecology, University of Oulu and Oulu University Hospital, Medical Research Center, PEDEGO Research Unit, Oulu, Finland.

Context: PCOS is associated with many traditional cardiovascular disease risk factors, but it is unclear whether PCOS is an independent risk factor for hypertension.

Objective: To investigate in a population-based set-up whether PCOS associates with the risk of hypertension independently of body-mass-index (BMI), and with cardiovascular manifestations.

Design: Cross-sectional assessments in the Northern Finland Birth Cohort 1966 at ages 31 and 46. Read More

View Article
November 2018
5 Reads

Comparison of groups with medical and surgical terminations of pregnancy.

Ceska Gynekol Fall 2018;83(4):244-249

Objective: The aim of this study was to compare two cohorts of subjects who underwent termination of pregnancy up to 49 days of amenorrhoea by medical (pharmacological) termination (faUUT) and surgical instrumental termination of pregnancy (inUUT).

Design: Prospective clinical study.

Setting: Department of Gynecology and Obstetrics, Charles University in Prague, 1st Faculty of Medicine, Hospital Na Bulovce. Read More

View Article
November 2018

Luteal phase stimulation, the future of fertility preservation? Retrospective cohort study of luteal phase versus follicular phase stimulation.

J Gynecol Obstet Hum Reprod 2018 Nov 12. Epub 2018 Nov 12.

Department of Gynecology, Centre Médico-Chirurgical d'Obstétrique (CMCO), Hôpitaux universitaires de Strasbourg, France.

Research Question: Is luteal phase stimulation capable of improving fertility preservation?

Materials And Methods: We performed a retrospective cohort study of consecutive ovarian stimulations, during July 2012 and September 2018 at Strasbourg University Teaching Hospital in France. Enrollment criteria were patients aged below 40 who had been referred to our center following a diagnosis of cancer or requiring gonadotoxic treatment. All patients enrolled had regular menstrual cycles and normal ovulation. Read More

View Article
November 2018
1 Read

Endocrine Conditions in Older Adults: Menopause.

FP Essent 2018 Nov;474:20-27

Department of Family Medicine MUSC, 5 Charleston Center Drive, Charleston, SC 29425.

Menopause is the cessation of menstruation due to loss of ovarian function and is diagnosed retrospectively after 12 consecutive months of amenorrhea. The average age of onset in the United States is 51 years but symptoms can be present for many years before and after. Vasomotor and genitourinary symptoms are the most common. Read More

View Article
November 2018
4 Reads

[Contraception for women after 40: CNGOF Contraception Guidelines].

Gynecol Obstet Fertil Senol 2018 Nov 10. Epub 2018 Nov 10.

Service de gynécologie et de médecine de la reproduction, centre Aliénor d'Aquitaine, CHU de Bordeaux, place Amélie Raba-Léon, 33076 Bordeaux cedex, France.

Introduction: Choosing contraception for women over 40 can be sometimes difficult but it is crucial since fertility and pregnancy's risks still exist. It requires a thorough evaluation of the situation, in order to identify any vascular and metabolic risk factors, along with the uterine and mammary benign pathologies already diagnosed.

Objective: The objective of this review was to elaborate some guidelines for clinical practice regarding contraception's prescription for women over 40. Read More

View Article
November 2018
4 Reads

The Relationship between Vitamin D Status and the Menstrual Cycle in Young Women: A Preliminary Study.

Nutrients 2018 Nov 11;10(11). Epub 2018 Nov 11.

Poznan University of Life Sciences, Institute of Human Nutrition and Dietetics, Dietetic Division, ul. Wojska Polskiego 28, 60-637 Poznań, Poland.

Background: The aim of this study was to evaluate serum vitamin D levels and to compare these with the menstrual cycle in young women with different body weights.

Methods: Eighty-four students were recruited into the study of which 77 remained at the study's completion. Women were assigned to one of two subgroups, according to their 25-hydroxy vitamin D test level [25(OH)D] in which 60 women had low 25(OH)D levels (LD < 30 ng/mL) and 17 had normal levels (ND > 30 ng/mL ≤ 80 ng/mL). Read More

View Article
November 2018

Links between HPA axis and adipokines: clinical implications in paradigms of stress-related disorders.

Expert Rev Endocrinol Metab 2018 Nov 13;13(6):317-332. Epub 2018 Nov 13.

a Unit of Endocrinology, Diabetes Mellitus and Metabolism, Aretaieion Hospital, School of Medicine , National and Kapodistrian University of Athens , Athens , Greece.

Introduction: In the human organism, a constant interplay exists between the stress system [which includes the activity of the hypothalamic-pituitary-adrenal (HPA) axis] and the adipose tissue. This interplay is mediated by hormones of the HPA axis such as corticotropin-releasing hormone (CRH), adrenocorticotropic hormone (ACTH) and glucocorticoids (GCs) and adipokines secreted by the adipose tissue. Areas covered: In this critical review, the bi-directional interactions between HPA axis and the most studied adipokines such as leptin and adiponectin, as well as the pro-inflammatory adipocytokines tumor necrosis factor (TNF) and interleukin (IL) 6 are presented. Read More

View Article
November 2018
3 Reads

A decade in female reproduction: an endocrine view of the past and into the future.

Hormones (Athens) 2018 Nov 12. Epub 2018 Nov 12.

Institute of Medical Physiology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia.

Over the last decade, huge achievements have been made in the fields of neurophysiology, molecular endocrinology, and biochemistry, as well as in the successful translation of clinical research into diseases into clinical practice. As regards female reproduction, most of the advances made in this area were achieved in gonadal axis regulation, regulation of behavior through sex steroids, reproductive genetics, preservation of ovarian reproductive function, steroid profiling, and metabolic and overall reproductive outcomes. The coming years are expected to bring further understanding of the relationships between nutrition, energy metabolism, and reproductive function and to succeed in identifying new genetic markers linked to adverse metabolic and unfavorable cardiovascular outcomes in women. Read More

View Article
November 2018
4 Reads

Access and utilisation of reproductive, maternal, neonatal and child health services among women who inject drugs in coastal Kenya: Findings from a qualitative study.

Sex Reprod Healthc 2018 Dec 6;18:48-55. Epub 2018 Oct 6.

Division of Health Research, Lancaster University, UK. Electronic address:

Introduction: The Kenyan government has committed to increasing access to comprehensive reproductive, maternal, neonatal and child health (RMNCH) services. However, inequalities still exist. Women who inject drugs are an important sub-population for public health interventions, yet their RMNCH needs have largely been overlooked. Read More

View Article
December 2018
3 Reads

Interstitial and Cornual Ectopic Pregnancy: Conservative Surgical and Medical Management.

J Obstet Gynaecol India 2018 Dec 28;68(6):471-476. Epub 2017 Nov 28.

Sir Ganga Ram Hospital Marg, Rajinder Nagar, New Delhi, 110060 India.

Background: Interstitial and cornual ectopic pregnancy is rare, accounting for 2-4% of ectopic pregnancies and remains the most difficult type of ectopic pregnancy to diagnose due to low sensitivity and specificity of symptoms and imaging. The classic triad of ectopic pregnancy-abdominal pain, amenorrhea and vaginal bleeding-occurs in less than 40% of patients. The site of implantation in the intrauterine portion of fallopian tube and invasion through the uterine wall make this pregnancy difficult to differentiate from an intrauterine pregnancy on ultrasound. Read More

View Article
December 2018
6 Reads

Spontaneous complete regression of large uterine fibroid after the second vaginal delivery: Case report.

Authors:
Myounghwan Kim

Medicine (Baltimore) 2018 Nov;97(45):e13092

Rationale: Fibroids are common, hormone-dependent, benign uterine tumors. It is estimated that they occur in 20% to 40% of women during their reproductive years. The prevalence of fibroids among pregnant women is 10. Read More

View Article
November 2018
4 Reads

Premature ovarian insufficiency may be associated with the mutations in mitochondrial tRNA genes.

Endocr J 2018 Nov 6. Epub 2018 Nov 6.

Central Laboratory, Hangzhou First People's Hospital, Zhejiang University, School of Medicine, Hangzhou, 310006, China.

Premature ovarian insufficiency (POI) is a common endocrine disorder featured by the triad constituting of amenorrhea for at least four months, to date, the molecular pathogenesis of POI is largely undetermined. Despite several investigations have reported an increase in reactive oxygen species (ROS) content in idiopathic POI, the role of mitochondrial DNA (mtDNA) mutations/variants in the progression of POI has not been widely investigated. The current study aimed to explore the association between mt-tRNA mutations/variants and POI; we first used the PCR-Sanger sequencing to detect the mutations/variants in mt-tRNA genes from 50 POI patients and 30 healthy subjects. Read More

View Article
November 2018

Female Athlete Triad.

Prim Care 2018 Dec 4;45(4):615-624. Epub 2018 Oct 4.

KentuckyOne Health, University of Louisville, Louisville, KY, USA; Department of Family and Geriatric Medicine, Centers for Primary Care, University of Louisville, 215 Central Avenue, Suite 205, Louisville, KY 40208, USA.

The female athlete triad is a condition seen in physically active female athletes, consisting of low energy availability, menstrual dysfunction, and low bone mineral density. The condition should be viewed as a metabolic injury. It can have an impact on female athletes at any age or level. Read More

View Article
December 2018
7 Reads

Being Reproductive.

Prim Care 2018 Dec 5;45(4):587-598. Epub 2018 Oct 5.

Department of Family Medicine, The Ohio State University, 2231 North High Street, Columbus, OH 43201, USA.

Women's reproductive health maintenance begins in the early years of growth and development. Routine care is the basis for early detection of menstrual dysfunction and delays or acceleration of physical development. Patients and their families may not address menstruation concerns because of the sensitive nature of the topic, the patient's self-conscious attitudes, and the parent's apprehension. Read More

View Article
December 2018
3 Reads

Virilising ovarian tumors: a single center experience.

Endocr Connect 2018 Nov 1. Epub 2018 Nov 1.

N Shah, Mumbai, 400012, India.

Aims: Literature on virilising ovarian tumors (VOT) is limited to case reports and series reporting single pathological type. We have analyzed the clinical, hormonal, radiological, histological, management and outcome data of VOT.

Materials And Methods: This retrospective study was conducted at a tertiary health care center from Western India. Read More

View Article
November 2018
3 Reads

Clinical and Laboratory Characteristics of Hyperprolactinemia in Children and Adolescents: National Survey.

J Clin Res Pediatr Endocrinol 2018 Nov 5. Epub 2018 Nov 5.

Objective: We aimed to study the characteristics on admission, diagnosis, treatment, and follow-up of hyperprolactinemic cases in a large multicenter study.

Methods: We reviewed 233 hyperprolactinemic patients under 18 years of age who were followed by different centers. The patients were divided as having microadenomas, macroadenomas, drug-induced hyperprolactinemia, and idiopathic hyperprolactinemia. Read More

View Article
November 2018
4 Reads

Control of endometriosis-associated pain with etonogestrel-releasing contraceptive implant and 52-mg levonorgestrel-releasing intrauterine system: randomized clinical trial.

Fertil Steril 2018 Nov;110(6):1129-1136

Department of Obstetrics and Gynecology, Faculty of Medical Sciences, University of Campinas, Campinas, São Paolo, Brazil. Electronic address:

Objective: To assess the efficacy of an etonogestrel (ENG)-releasing contraceptive implant or the 52-mg levonorgestrel-releasing intrauterine system (LNG-IUS) in the control of endometriosis-associated pelvic pain.

Design: Noninferiority randomized clinical trial in which women with endometriosis were assigned to use an ENG implant (experimental treatment) or an LNG-IUS (active comparator). Monthly follow-up visits were conducted up to 6 months. Read More

View Article
November 2018
3 Reads

The Female Athlete Triad: A Comparison of Knowledge and Risk in Adolescent and Young Adult Figure Skaters, Dancers and Runners.

J Pediatr Adolesc Gynecol 2018 Nov 2. Epub 2018 Nov 2.

Division of Adolescent Medicine, Department of Pediatrics, Children's Hospital at Montefiore, 3415 Bainbridge Ave, Bronx, NY, USA 10467. Electronic address:

Study Objective: The Female Athlete Triad is often found in sports that value leanness and aesthetics and can lead to adverse health effects. We aimed to compare knowledge and risk of the Triad among adolescent figure skaters, dancers, and runners.

Design, Setting, Participants, Main Outcome Measures: We advertised our survey on social media platforms: sports-specific forums; Facebook; and Instagram. Read More

View Article
November 2018
7 Reads

Predictive factors of preterm delivery in French Guiana for singleton pregnancies: definition and validation of a predictive score.

J Matern Fetal Neonatal Med 2018 Nov 4:1-8. Epub 2018 Nov 4.

a Cayenne Hospital Center , Cayenne , French Guiana.

Objective: Given the high rate of premature birth in French Guiana (13.5%), and its stability in time, the aim of the present study was to define a predictive score for preterm birth in women with a unique pregnancy in order to help prioritize health resources in the local context.

Methods: A retrospective study was conducted on all deliveries of unique pregnancies in French Guiana collected between 1 January 2013 and 31 December 2014 in the Registre d'Issue de Grossesse Informatisé (RIGI), a registry that collects data on live births over 22 weeks of amenorrhea on the territory. Read More

View Article
November 2018
3 Reads

Pretreatment anti-Mullerian hormone-based nomogram predicts menstruation status after chemotherapy for premenopausal women with hormone receptor-positive early breast cancer.

Breast Cancer Res Treat 2018 Nov 3. Epub 2018 Nov 3.

Department of Medical Oncology, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Dongfeng Road East 651#, Guangzhou, 510060, China.

Purpose: Ovarian function is important for optimizing endocrine treatment in patients with hormone receptor-positive (HR+) early breast cancer (eBC). The aim of the study was to determine whether patients' pretreatment levels of anti-Mullerian hormone (AMH) were associated with menses status after chemotherapy and to build a predictive nomogram model for amenorrhea in women with HR+ eBC.

Methods: Between August 2013 and December 2014, 120 premenopausal patients with HR+ eBC were included retrospectively. Read More

View Article
November 2018
3 Reads
3.940 Impact Factor

[Natural Family Planning methods and Barrier: CNGOF Contraception Guidelines].

Authors:
D Hassoun

Gynecol Obstet Fertil Senol 2018 Oct 30. Epub 2018 Oct 30.

38, rue de Turenne, 75003 Paris, France. Electronic address:

Objective: To develop clinical practice recommendations for the use of natural contraception and female and male barrier methods.

Materials And Methods: A systematic review of English and French literatures related to the safety and effectiveness of natural contraceptive methods based on PubMed, Cochrane Library, practice recommendations issued by international scientific societies and guidelines provided by the World Health Organization (WHO) as well as updates from the Center for Disease Control and Prevention (CDC).

Results: Natural contraceptives methods include fertility awareness-based methods, lactational amenorrhea method (LAM) and withdrawal method. Read More

View Article
October 2018
1 Read

Rare case of occult testosterone-producing ovarian tumor that was diagnosed by selective venous hormone sampling.

Reprod Med Biol 2018 Oct 21;17(4):504-508. Epub 2018 Jun 21.

Department of Obstetrics and Gynecology Sapporo Medical University School of Medicine Sapporo Japan.

Case: A 32 year old woman was referred because of secondary amenorrhea, hirsutism, and voice deepening.

Outcome: The blood testosterone level was markedly high. A transvaginal ultrasound revealed a small region in the left ovary, but whether or not it was a tumor was unclear. Read More

View Article
October 2018
1 Read

Bevacizumab for Hearing Preservation in Neurofibromatosis Type 2: Emphasis on Patient-Reported Outcomes and Toxicities.

Otolaryngol Head Neck Surg 2018 Oct 30:194599818809085. Epub 2018 Oct 30.

1 Department of Pediatric Hematology/Oncology, University of Minnesota, Minneapolis, Minnesota, USA.

Objective: Bevacizumab for hearing preservation in patients with neurofibromatosis type 2 (NF2) is an emerging practice. We set out to characterize the effectiveness and toxicity of bevacizumab in our patient group.

Study Design: Case series with chart review. Read More

View Article
October 2018
9 Reads

Efficacy of a Herbal Formulation Based on Foeniculum Vulgare in Oligo/Amenorrhea: A Randomized Clinical Trial.

Curr Drug Discov Technol 2018 Oct 29. Epub 2018 Oct 29.

Department of Persian Medicine, School of Persian and Complementary Medicine, Mashhad University of Medical Sciences, Mashhad. Iran.

Background: The aim of this study was to evaluate the efficacy of the herbal tea based on Foeniculum vulgare, on inducing regular bleeding in women with oligomenorrhea and secondary amenorrhea(oligo/amenorrhea).

Methods: Forty women aged 18- 40 with oligo/amenorrhea were enrolled in this randomized controlled clinical trial and were allocated to two groups equally. The women in the first group were treated by Fomentex (Foeniculum vulgare / Mentha longifolia / Vitex agnus-castus) herbal tea 11. Read More

View Article
October 2018
5 Reads