14,866 results match your criteria Amebiasis


The mitosome of the anaerobic parasitic protist Entamoeba histolytica: a peculiar and minimalist mitochondrion-related organelle.

J Eukaryot Microbiol 2022 May 19:e12923. Epub 2022 May 19.

Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.

The simplest class of mitochondrion-related organelles (MROs) is the mitosome, an organelle present in a few anaerobic protozoan parasites such as Entamoeba histolytica, Giardia intestinalis, and Cryptosporidium parvum. E. histolytica causes amoebiasis in humans, deemed as one of the important, yet neglected tropical infections in the world. Read More

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Neurotrophic Factors in Experimental Cerebral Acanthamoebiasis.

Int J Mol Sci 2022 Apr 29;23(9). Epub 2022 Apr 29.

Independent Laboratory of Pharmaceutical Botany, Pomeranian Medical University in Szczecin, 70-204 Szczecin, Poland.

To date, no studies have addressed the role of neurotrophins (NTs) in spp. infections in the brain. Thus, to clarify the role of NTs in the cerebral cortex and hippocampus during experimental acanthamoebiasis in relation to the host immune status, the purpose of this study was to determine whether spp. Read More

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Fulminant necrotizing amoebic colitis presenting as acute appendicitis: a case report and comprehensive literature review.

J Infect Dev Ctries 2022 Apr 30;16(4):717-725. Epub 2022 Apr 30.

Department of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia / Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia.

Intestinal amoebiasis is a parasitic infection caused by Entamoeba histolytica. It is commonly found in developing countries with poor hygiene. A rare, life-threatening complication of amoebiasis is fulminant necrotizing amoebic colitis (FulNAC). Read More

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Acanthamoeba keratitis: an increasingly common infectious disease of the cornea.

Lancet Microbe 2021 Aug 25;2(8):e345-e346. Epub 2021 May 25.

School of Optometry and Vision Science, Faculty of Medicine and Health, University of New South Wales, Sydney, NSW, Australia.

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Endemic Thoracic Infections in Sub-Saharan Africa.

Radiol Clin North Am 2022 May;60(3):461-479

Alliar Group, Rua Ernesto Nazaré, 389 - Alto de Pinheiros, São Paulo, São Paulo 05462-000, Brazil.

Although many of the thoracic infections endemic to Africa are also present around the world, this article focuses on entities that are emerging or disproportionately affect populations living in sub-Saharan Africa. Important emerging or reemerging viral and bacterial diseases that commonly affect the lung include dengue fever, plague, leptospirosis, and rickettsioses. Most parasitic infections endemic to Africa can also manifest within the thorax, including malaria, amebiasis, hydatid disease, schistosomiasis, paragonimiasis, ascariasis, strongyloidiasis and cysticercosis. Read More

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Endemic Thoracic Infections in Latin America and the Caribbean.

Radiol Clin North Am 2022 May;60(3):429-443

The University of Texas Health Science Center at San Antonio.

Infectious diseases, including parasitic diseases, which are commonly associated with poverty and poor sanitation, continue to cause significant morbidity, disability, and mortality in Latin America and the Caribbean region. This article reviews the epidemiology, pathophysiology, and cardiothoracic imaging manifestation of several communicable diseases endemic to this region. Read More

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Isolated amoebic brain abscess with excellent therapeutic response.

Rev Soc Bras Med Trop 2022 29;55:e00502022. Epub 2022 Apr 29.

Uniclinic Diagnóstico por Imagem, Fortaleza, CE, Brasil.

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[Parasite screening for immunosuppressed traveler].

Rev Med Suisse 2022 May;18(780):898-902

Service de médecine tropicale et humanitaire, Département de médecine de premier recours, Hôpitaux universitaires de Genève, 1211 Genève 14.

Before starting immunosuppressive therapy, it is important to screen for latent tuberculosis and, in case of particular exposures (e.g. travel, origin,…), for parasitosis such as amoebiasis, echinococcosis, strongyloidiasis and American trypanosomiasis. Read More

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Natural infection ofBlastocystis ST6 among commercial quails (Coturnix coturnix) in Penang, Malaysia.

Trop Biomed 2022 Mar;39(1):73-77

School of Biological Sciences, Universiti Sains Malaysia, 11800 USM Penang, Malaysia.

Blastocystis sp. is a unicellular, anaerobic intestinal protist regularly reported in humans and various animals worldwide. There seems to be little research on Blastocystis infection in poultry in Malaysia, and none on Blastocystis in quail specifically. Read More

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Subacute encephalitis in an immunocompetent patient diagnosed by next-generation sequencing.

J Int Med Res 2022 May;50(5):3000605221093217

Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China.

is a free-living heterotrophic amoeba found in soil that causes a rare and usually fatal granulomatous amebic encephalitis. We report an immunocompetent patient infected with encephalitis diagnosed by next-generation sequencing (NGS). Clinical manifestations included sudden headache and epilepsy with disturbance of consciousness. Read More

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Specific Detection of Acanthamoeba species using Polyclonal Peptide Antibody Targeting the Periplasmic Binding Protein of A. castellanii.

Korean J Parasitol 2022 Apr 20;60(2):143-147. Epub 2022 Apr 20.

Department of Medical Zoology, Kyung Hee University School of Medicine, Seoul 02447, Korea.

Acanthamoeba keratitis (AK) is a rare ocular disease, but it is a painful and sight-threatening infectious disease. Early diagnosis and adequate treatment are necessary to prevent serious complications. While AK is frequently diagnosis via several PCR assays or Acanthamoeba-specific antibodies, a more specific and effective diagnostic method is required. Read More

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Serological levels of cytokines in irritable bowel syndrome (IBS) patients and non-IBS subjects with and without Blastocystis spp. infection.

Ann Parasitol 2022 ;68(1):77-85

Department of Biology, College of Sciences, Mustansiriyah University, Baghdad, Iraq.

The objectives of the present study were to investigate the prevalence of Blastocystis spp. and to determine the levels of some pro-and anti-inflammatory cytokines in patients with irritable bowel syndrome (IBS) and without Blastocystis infection in comparison with non-IBS control individuals. Stool samples were collected from 250 IBS patients and 100 samples from controls, examined for the presence of Blastocystis and the percentage of infection was recorded. Read More

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The circulating plasma metabolome of Neoparamoeba perurans-infected Atlantic salmon (Salmo salar).

Microb Pathog 2022 May 25;166:105553. Epub 2022 Apr 25.

Norwegian Veterinary Institute, 1433, Ås, Norway.

Metabolomics can provide insights into the dynamic small-molecule fluctuations occurring in response to infection and has become a valuable tool in studying the pathophysiology of diseases in recent years. However, its application in fish disease research is limited. Here, we report the circulating plasma metabolome of Atlantic salmon (Salmo salar) experimentally infected with Neoparamoeba perurans-the causative agent of amoebic gill disease (AGD). Read More

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Fulminant necrotising amoebic colitis: a report of two cases.

Hong Kong Med J 2022 Apr;28(2):172-174

Department of Surgery, Caritas Medical Centre, Hong Kong.

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Cecal ameboma and liver abscess mimicking metastatic colonic cancer. An autochthonous infectious disease in Spain?

Rev Esp Enferm Dig 2022 Apr 26. Epub 2022 Apr 26.

Gastroenterology , Hospital Universitario Río Hortega, España.

We present the case of 52 years-old male without any recent travel. He was admitted to our department for a history of fever and abdominal pain. A CT scan showed a cecal thickening and liver mass with suspected cecal carcinoma with infected necrotic liver metastasis. Read More

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Identification of asymptomatic Entamoeba histolytica infection by a serological screening test: A cross-sectional study of an HIV-negative men who have sex with men cohort in Japan.

PLoS Negl Trop Dis 2022 04 25;16(4):e0009793. Epub 2022 Apr 25.

AIDS Clinical Center, National Center for Global Health and Medicine, Tokyo, Japan.

Background: Amebiasis, caused by Entamoeba histolytica, is spreading in developing countries and in many developed countries as a sexually transmitted infection. Here, we evaluated the efficacy of serological screening to identify asymptomatic E. histolytica infection as a potential epidemiological control measure to limit its spread. Read More

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Mechanism of Action of Shenerjiangzhi Formulation on Hyperlipidemia Induced by Consumption of a High-Fat Diet in Rats Using Network Pharmacology and Analyses of the Gut Microbiota.

Front Pharmacol 2022 5;13:745074. Epub 2022 Apr 5.

Institute of Traditional Chinese Medicine, Heilongjiang University of Chinese Medicine, Harbin, China.

Shenerjiangzhi formulation (SEJZ) is a new traditional Chinese medicine formulation (patent number: CN110680850A). SEJZ contains ( and ), (Araliaceae; radix and rhizome), Thunb (Caprifoliaceae; branch, stem), Bunge (Rosaceae; Crataegus pinnatifida fruit), and . SEJZ has been designed to treat hyperlipidemia. Read More

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A Review: Natural and Synthetic Compounds Targeting and Its Biological Membrane.

Membranes (Basel) 2022 Apr 1;12(4). Epub 2022 Apr 1.

Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, Gelugor 11800, Malaysia.

Amoebiasis is the third most common parasitic cause of morbidity and mortality, particularly in countries with poor hygienic settings in central and south America, Africa, and India. This disease is caused by a protozoan parasite, namely , which infects approximately 50 million people worldwide, resulting in 70,000 deaths every year. Since the 1960s, infection has been successfully treated with metronidazole. Read More

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A rare case of extraintestinal amebiasis.

BMC Infect Dis 2022 Apr 11;22(1):364. Epub 2022 Apr 11.

Department of Critical care Medicine, Affiliated Hospital of Zunyi Medical University, Dalian Road 149, Zunyi City, 563003, Guizhou, China.

Background: Amoebiasis is caused by the protozoan Entamoeba histolytica, which is a rare infectious disease in developed countries. If the trophozoites enter the blood, it can spread through the body, such as brain, and lungs. Cases of simultaneous infection of multiple organs are extremely rare. Read More

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Entamoeba histolytica EHD1 Is Involved in Mitosome-Endosome Contact.

mBio 2022 Apr 11;13(2):e0384921. Epub 2022 Apr 11.

Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyogrid.26999.3d, Tokyo, Japan.

Interorganellar cross talk is often mediated by membrane contact sites (MCSs), which are zones where participating membranes come within 30 nm of one another. MCSs have been found in organelles, including the endoplasmic reticulum, Golgi bodies, endosomes, and mitochondria. Despite its seeming ubiquity, reports of MCS involving mitochondrion-related organelles (MROs) present in a few anaerobic parasitic protozoa remain lacking. Read More

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Prevalence of Amoebiasis and Associated Complications in India: A Systematic Review.

Acta Parasitol 2022 Apr 11. Epub 2022 Apr 11.

Department of Microbiology, Central University of Punjab, Bathinda, Punjab, 151401, India.

Purpose: Intestinal protozoan parasites are responsible for diarrheal diseases causing significant morbidity and mortality. Entamoeba histolytica is the principle protozoan parasite associated with diarrheal infections. The infection is often associated with inaccessibility to clean drinking water and poor sanitary conditions in low- and middle-income countries including India. Read More

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Comparative transcriptome profiling of virulent and avirulent isolates of Neoparamoeba perurans.

Sci Rep 2022 04 7;12(1):5860. Epub 2022 Apr 7.

Institute for Marine and Antarctic Studies, University of Tasmania, Launceston, TAS, Australia.

Neoparamoeba perurans, the aetiological agent of amoebic gill disease, remains a persistent threat to Atlantic salmon mariculture operations worldwide. Innovation in methods of AGD control is required yet constrained by a limited understanding of the mechanisms of amoebic gill disease pathogenesis. In the current study, a comparative transcriptome analysis of two N. Read More

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Ascorbic Acid Ameriolates Liver Damage by Myeloperoxidase Oxidative Products in a Hamster Model of Amoebic Liver Abscess.

Front Cell Infect Microbiol 2022 22;12:855822. Epub 2022 Mar 22.

Sección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Ciudad de México (CDMX), México.

is a protozoan-pathogen-causing amoebic liver abscess (ALA). After amoeba establishment in the liver, it causes abundant infiltrate of neutrophils. Liver tissue damage by neutrophils results in part from anti-amoebic oxidative intermediates, including reactive oxygen species (ROS), reactive nitrogen species (RNS), and hypochlorous acid (HOCl), derived from the myeloperoxidase (MPO) enzyme. Read More

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A Case of Intestinal Amoebiasis Mimicking Intestinal Behçet's Disease.

Mod Rheumatol Case Rep 2022 Apr 5. Epub 2022 Apr 5.

Department of Rheumatology and Clinical Immunology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

Intestinal amoebiasis is caused by Entamoeba histolytica (E. histolytica) and is characterized by cecal lesions, multiple lesions, aphthae, and multiple exudative erosions. Intestinal Behçet's disease (BD) is a chronic inflammatory disorder that is characterized by multiple ulcers. Read More

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Ruthenium metallotherapeutics: novel approaches to combatting parasitic infections.

Curr Med Chem 2022 Apr 1. Epub 2022 Apr 1.

Faculty of Science and Engineering, Manchester Metropolitan University, Manchester, United Kingdom.

Human parasitic infections cause a combined global mortality rate of over one million people per annum and represent some of the most challenging diseases for medical intervention. Current chemotherapeutic strategies often require prolonged treatment, coupled with subsequent drug-induced cytotoxic morbidity to the host, while resistance generation is also a major concern. Metals have been used extensively throughout the history of medicine, with more recent applications as anticancer and antimicrobial agents. Read More

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Ubiquitin of Entamoeba histolytica induces antibody response in patients with invasive amoebiasis.

Parasite Immunol 2022 Apr 2:e12919. Epub 2022 Apr 2.

Universidad Autónoma de Nuevo León, Facultad de Ciencias Biológicas, Instituto de Biotecnología, San Nicolás de los Garza, Mexico.

Entamoeba histolytica causes amoebic liver abscess (ALA) in humans. The injury of target cells by E. histolytica includes processes controlled by the ubiquitin Ehub. Read More

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First report of spp. subtypes in ZOO animals in Slovakia, Central Europe.

Ann Agric Environ Med 2022 Mar 27;29(1):149-151. Epub 2022 Jan 27.

University of Veterinary Medicine and Pharmacy, Košice, Slovak Republic.

spp. has been reported in wildlife, domestic animals and animals housed in ZOO. To-date, 17 genetically diverse lines have been reported in mammals and birds (designated ST) based on differences in the SSU rRNA. Read More

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Quantitative Proteomics Reveals Metabolic Reprogramming in Host Cells Induced by Trophozoites and Intermediate Subunit of Gal/GalNAc Lectins from Entamoeba histolytica.

mSystems 2022 Apr 28;7(2):e0135321. Epub 2022 Mar 28.

Department of Medical Microbiology and Parasitology, School of Basic Medical Sciences, Fudan University, Shanghai, China.

Entamoeba histolytica is an intestinal protozoan parasite with remarkable ability to kill and phagocytose host cells, causing amoebic colitis and extraintestinal abscesses. The intermediate subunit (Igl) of galactose (Gal)- and -acetyl-d-galactosamine (GalNAc)-specific lectins is considered an important surface antigen involved in the pathogenesis of E. histolytica. Read More

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Potent anti-amoebic effects of Ibogaine, Voacangine and the root bark alkaloid fraction of Tabernaemontana arborea.

Planta Med 2022 Mar 25. Epub 2022 Mar 25.

Universidad Nacional Autonoma de Mexico Instituto de Investigaciones Biomedicas, Ciudad de Mexico, Mexico.

Plants of species have several pharmacological activities including antimicrobial effects. Amoebiasis continues to be a public health problem with increasing evidence of resistance to metronidazole. In this study we assessed the effect of the alkaloid fraction of root bark and its alkaloids ibogaine and voacangine on the viability and infectivity of trophozoites. Read More

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