1,335 results match your criteria Ambulatory EEG

Sleep architectural dysfunction and undiagnosed obstructive sleep apnea after chronic ischemic stroke.

Sleep Med 2021 Apr 15;83:45-53. Epub 2021 Apr 15.

The Florey Institute of Neuroscience and Mental Health, Melbourne, VIC, Australia; University of Melbourne, Melbourne, VIC, Australia.

Objective/background: Sleep-wake dysfunction is bidirectionally associated with the incidence and evolution of acute stroke. It remains unclear whether sleep disturbances are transient post-stroke or are potentially enduring sequelae in chronic stroke. Here, we characterize sleep architectural dysfunction, sleep-respiratory parameters, and hemispheric sleep in ischemic stroke patients in the chronic recovery phase compared to healthy controls. Read More

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Healthcare utilization and cost outcomes for a multicenter first seizure and new onset epilepsy clinic.

Epilepsy Behav 2021 May 7;120:107972. Epub 2021 May 7.

Western University of Health Sciences College of Osteopathic Medicine of the Pacific, Northwest, 200 Mullins Dr, Lebanon, OR 97355, United States; Providence Brain and Spine Institute, 9135 SW Barnes Rd., Suite 363, Portland, OR 97225, United States.

Rationale: A First Seizure/New Onset Epilepsy (FS/NOE) protocol was implemented to ensure proper evaluation by an epileptologist and improve overall care for patients. We compared healthcare utilization and cost incurred by patients pre and post protocol implementation.

Methods: Clinical data were retrospectively collected from the EMR and cost data from the financial database. Read More

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Acute effects of brain-responsive neurostimulation in drug-resistant partial onset epilepsy.

Clin Neurophysiol 2021 Mar 31. Epub 2021 Mar 31.

NeuroPace, Inc., Mountain View, CA, USA.

Objective: Understanding the acute effects of responsive stimulation (AERS) based on intracranial EEG (iEEG) recordings in ambulatory patients with drug-resistant partial epilepsy, and correlating these with changes in clinical seizure frequency, may help clinicians more efficiently optimize responsive stimulation settings.

Methods: In patients implanted with the NeuroPace® RNS® System, acute changes in iEEG spectral power following active and sham stimulation periods were quantified and compared within individual iEEG channels. Additionally, acute stimulation-induced acute iEEG changes were compared within iEEG channels before and after patients experienced substantial reductions in clinical seizure frequency. Read More

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Hybrid algorithm for multi artifact removal from single channel EEG.

Biomed Phys Eng Express 2021 May 11;7(4). Epub 2021 May 11.

Department of Electronics and Communication Engineering, Pondicherry Engineering College, Puducherry-605014, India.

Electroencephalogram (EEG) signals recorded from the ambulatory systems are mostly contaminated by various artifacts like, electrooculogram (EOG), motion artifacts (MA) and electrocardiogram (ECG) artifacts. These artifacts limit the accuracy in further analysis of EEG in practise. So far, several existing methods have been proposed with the combination of decomposition techniques and independent component analysis (ICA) to remove single artifacts and only few methods to remove multiple artifacts from the single channel EEG. Read More

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Evidence of Neurovascular Un-Coupling in Mild Alzheimer's Disease through Multimodal EEG-fNIRS and Multivariate Analysis of Resting-State Data.

Biomedicines 2021 Mar 26;9(4). Epub 2021 Mar 26.

Department of Neuroscience, Imaging and Clinical Sciences, Institute for Advanced Biomedical Technologies, Faculty of Medicine, University G. D'Annunzio of Chieti-Pescara, Via Luigi Polacchi 13, 66100 Chieti, Italy.

Alzheimer's disease (AD) is associated with modifications in cerebral blood perfusion and autoregulation. Hence, neurovascular coupling (NC) alteration could become a biomarker of the disease. NC might be assessed in clinical settings through multimodal electroencephalography (EEG) and functional near-infrared spectroscopy (fNIRS). Read More

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Quantifying Physiological Biomarkers of a Microwave Brain Stimulation Device.

Sensors (Basel) 2021 Mar 8;21(5). Epub 2021 Mar 8.

Center for Medical Convergence Metrology, Korea Research Institute of Standards and Science, Daejeon 34113, Korea.

Physiological signals are immediate and sensitive to neural and cardiovascular change resulting from brain stimulation, and are considered as a quantifying tool with which to evaluate the association between brain stimulation and cognitive performance. Brain stimulation outside a highly equipped, clinical setting requires the use of a low-cost, ambulatory miniature system. The purpose of this double-blind, randomized, sham-controlled study is to quantify the physiological biomarkers of the neural and cardiovascular systems induced by a microwave brain stimulation (MBS) device. Read More

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Implementation of Multimodality Neurologic Monitoring Reporting in Pediatric Traumatic Brain Injury Management.

Neurocrit Care 2021 Mar 31. Epub 2021 Mar 31.

Department of Neurosciences, Barrow Neurological Institute At Phoenix Children's Hospital, 1919 E. Thomas Road, Ambulatory Building B, 3rd floor, Phoenix, AZ, 85016, USA.

Background/objective: Multimodality neurologic monitoring (MMM) is an emerging technique for management of traumatic brain injury (TBI). An increasing array of MMM-derived biomarkers now exist that are associated with injury severity and functional outcomes after TBI. A standardized MMM reporting process has not been well described, and a paucity of evidence exists relating MMM reporting in TBI management with functional outcomes or adverse events. Read More

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Prolonged epileptic discharges predict seizure recurrence in JME: Insights from prolonged ambulatory EEG.

Epilepsia 2021 May 18;62(5):1184-1192. Epub 2021 Mar 18.

Department of Clinical and Experimental Medicine, Neurological Clinic, University of Pisa, Pisa, Italy.

Objective: Markers of seizure recurrence are needed to personalize antiseizure medication (ASM) therapy. In the clinical practice, EEG features are considered to be related to the risk of seizure recurrence for genetic generalized epilepsies (GGE). However, to our knowledge, there are no studies analyzing systematically specific EEG features as indices of ASM efficacy in GGE. Read More

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Non-invasive wearable seizure detection using long-short-term memory networks with transfer learning.

J Neural Eng 2021 Apr 8;18(5). Epub 2021 Apr 8.

Bioelectronics Neurology and Engineering Laboratory, Department of Neurology, Mayo Clinic, Alfred 9-441C, 200 First Street SW, Rochester, MN 55905, United States of America.

. The detection of seizures using wearable devices would improve epilepsy management, but reliable detection of seizures in an ambulatory environment remains challenging, and current studies lack concurrent validation of seizures using electroencephalography (EEG) data.. Read More

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The unchanging face of Lennox-Gastaut syndrome in adulthood.

Epilepsy Res 2021 May 13;172:106575. Epub 2021 Feb 13.

Istanbul University-Cerrahpasa, Cerrahpasa Faculty of Medicine, Department of Neurology, 34098, Istanbul, Turkey. Electronic address:

Purpose: Lennox-Gastaut syndrome (LGS) is a severe childhood-onset epileptic encephalopathy characterized by the presence of multiple types of intractable seizures, cognitive impairment, and specific electroencephalogram (EEG) patterns. The aim of this study was to investigate the electroclinical features of patients with LGS during adulthood.

Methods: We retrospectively identified the medical records of 20 patients aged over 18 years with a diagnosis of LGS from 3896 patients with epilepsy. Read More

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Sonographic hypoechogenicity of brainstem raphe nucleus is correlated with electroencephalographic spike frequency in patients with epilepsy.

Epilepsy Behav 2021 04 11;117:107884. Epub 2021 Mar 11.

Department of Neurology, Epilepsy and Headache Group, the First Affiliated Hospital of Anhui Medical University, Jixi Road 218, Hefei 230022, China. Electronic address:

Background: Brainstem raphe nucleus (BRN) hypoechogenicity in transcranial sonography (TCS) has been demonstrated in patients with major depression, possibly representing a sonographic manifestation of serotonergic dysfunction in depression. Most patients with epilepsy with comorbid depression exhibit hypoechogenic BRN in TCS. However, the role of BRN in the pathogenesis of epilepsy is unclear. Read More

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Closed-Loop Acoustic Stimulation During Sedation with Dexmedetomidine (CLASS-D): Protocol for a Within-Subject, Crossover, Controlled, Interventional Trial with Healthy Volunteers.

Nat Sci Sleep 2021 4;13:303-313. Epub 2021 Mar 4.

Department of Anesthesiology, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.

Introduction: The relative power of slow-delta oscillations in the electroencephalogram (EEG), termed slow-wave activity (SWA), correlates with level of unconsciousness. Acoustic enhancement of SWA has been reported for sleep states, but it remains unknown if pharmacologically induced SWA can be enhanced using sound. Dexmedetomidine is a sedative whose EEG oscillations resemble those of natural sleep. Read More

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Ambulatory EEG Usefulness in Epilepsy Management.

J Clin Neurophysiol 2021 Mar;38(2):101-111

Department of Neurology, Mayo Clinic, Jacksonville, Florida, U.S.A.

Summary: Long-term video-EEG monitoring has been the gold standard for diagnosis of epileptic and nonepileptic events. Medication changes, safety, and a lack of recording EEG in one's habitual environment may interfere with diagnostic representation and subsequently affect management. Some spells defy standard EEG because of ultradian and circadian times of occurrence, manifest nocturnal expression of epileptiform activity, and require classification for clarifying diagnostic input to identify optimal treatment. Read More

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Long-term Home Video EEG for Recording Clinical Events.

J Clin Neurophysiol 2021 Mar;38(2):92-100

Comprehensive Epilepsy Center, Department of Neurology, University of Texas Health Science Center at Houston, Houston, Texas, U.S.A.

Summary: Around 50 years after the first EEG acquisition by Hans Berger, its use in ambulatory setting was demonstrated. Ever since, ambulatory EEG has been widely available and routinely used in the United States (and to a lesser extent in Europe) for diagnosis and management of patients with epilepsy. This technology alone cannot help with semiological characterization, and absence of video is one of its main drawbacks. Read More

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Ambulatory EEG to Classify the Epilepsy Syndrome.

J Clin Neurophysiol 2021 Mar;38(2):87-91

Department of Neurology, Northwestern University, Chicago, Illinois, U.S.A.

Summary: Recording of interictal epileptiform discharges to classify the epilepsy syndrome is one of the most common indications for ambulatory EEG. Ambulatory EEG has superior sampling compared with standard EEG recordings and advantages in terms of cost-effectiveness and convenience compared with a prolonged inpatient EEG study. Ambulatory EEG allows for EEG recording in all sleep stages and transitional states, which can be very helpful in capturing interictal epileptiform discharges. Read More

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Ambulatory EEG Monitoring, Reviewing, and Interpreting.

Donald L Schomer

J Clin Neurophysiol 2021 Mar;38(2):77-86

Division of Epilepsy and Clinical Neurophysiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, U.S.A.

Summary: This section of this volume of the Journal of Neurophysiology's review of ambulatory EEG (aEEG) is an overview of the uses of the technique, the clinicians who most often use it, and why they use it. It looks at the use of aEEG from the perspectives of the "generalist" and the "specialist" and discusses where they have similar interests and where their interest may diverge. It compares the use of aEEG to the more classic inpatient-based epilepsy monitoring unit service and compares the advantages and disadvantages of the two approaches (aEEG vs. Read More

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Utility of Ambulatory Surface Electroencephalography.

J Clin Neurophysiol 2021 Mar;38(2):75-76

Mayo Clinic, Jacksonville, Florida, U.S.A.

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Indications and yield of ambulatory EEG recordings.

Epileptic Disord 2021 Feb;23(1):94-103

Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

To study the yield of prolonged ambulatory electroencephalogram (aEEG). A retrospective chart review of all patients who underwent aEEG studies between 2013 and 2017 was performed. Reasons for aEEG were classified into five categories: detection of interictal epileptiform discharges (IEDs), capturing clinical events, detection of unrecognized seizures, monitoring IEDs during treatment, and unclassifiable. Read More

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February 2021

Elucidation of EEG Characteristics of Fuzzy Reasoning-Based Heuristic BCI and Its Application to Patient With Brain Infarction.

Front Neurorobot 2020 25;14:607706. Epub 2021 Jan 25.

Department of Human System Interaction, School of Science and Technology, Kwansei Gakuin University, Sanda, Japan.

Non-invasive brain-computer interfaces (BCIs) based on common electroencephalography (EEG) are limited to specific instrumentation sites and frequency bands. These BCI induce certain targeted electroencephalographic features of cognitive tasks, identify them, and determine BCI's performance, and use machine-learning to extract these electroencephalographic features, which makes them enormously time-consuming. In addition, there is a problem in which the neurorehabilitation using BCI cannot receive ambulatory and immediate rehabilitation training. Read More

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January 2021

The effects of coronavirus disease 2019 (COVID-19) pandemic on people with epilepsy (PwE): an online survey-based study.

Acta Neurol Belg 2021 Feb 8. Epub 2021 Feb 8.

Department of Neurology, Ibn Sina Hospital, Sabah Medical Area, Kuwait, Kuwait.

During the unprecedented COVID-19 pandemic in 2020, the whole world faced an unusual health emergency. Medical care of chronic neurological diseases, such as Epilepsy, is being neglected. In this survey, we aimed to evaluate the impact of the COVID-19 pandemic on the care of people with Epilepsy (PwE) and to identify their risk factors for seizure worsening to direct better future medical care. Read More

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February 2021

Cycles of self-reported seizure likelihood correspond to yield of diagnostic epilepsy monitoring.

Epilepsia 2021 02 28;62(2):416-425. Epub 2021 Jan 28.

Department of Medicine, St Vincent's Hospital, University of Melbourne, Melbourne, Vic., Australia.

Objective: Video-electroencephalography (vEEG) is an important component of epilepsy diagnosis and management. Nevertheless, inpatient vEEG monitoring fails to capture seizures in up to one third of patients. We hypothesized that personalized seizure forecasts could be used to optimize the timing of vEEG. Read More

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February 2021

Mobile EEG reveals functionally dissociable dynamic processes supporting real-world ambulatory obstacle avoidance: Evidence for early proactive control.

Eur J Neurosci 2021 Jan 19. Epub 2021 Jan 19.

Psychology, Faculty of Natural Sciences, University of Stirling, Stirling, UK.

The ability to safely negotiate the world on foot takes humans years to develop, reflecting the extensive cognitive demands associated with real-time planning and control of walking. Despite the importance of walking, methodological limitations mean that surprisingly little is known about the neural and cognitive processes that support ambulatory motor control. Here, we report mobile EEG data recorded from 32 healthy young adults during real-world ambulatory obstacle avoidance. Read More

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January 2021

Effect of prior general anesthesia or sedation and antiseizure drugs on the diagnostic utility of wireless video electroencephalography in dogs.

J Vet Intern Med 2020 Sep 13;34(5):1967-1974. Epub 2020 Jul 13.

Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada.

Background: Ambulatory wireless video electroencephalography (AEEG) is the method of choice to discriminate epileptic seizures from other nonepileptic episodes. However, the influence of prior general anesthesia (GA), sedation, or antiseizure drug (ASD) on the diagnostic ability of AEEG is unknown.

Hypothesis/objectives: The use of sedation/GA or ASD treatment before AEEG recording may affect the diagnostic ability of AEEG and the time to first abnormality on AEEG. Read More

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September 2020

Associations between daily affect and sleep vary by sleep assessment type: What can ambulatory EEG add to the picture?

Sleep Health 2021 Apr 14;7(2):219-228. Epub 2021 Jan 14.

Department of Psychology, University of North Texas, 1155 Union Circle #311280, Denton, TX 76203, USA.

Objective/background: Disrupted sleep can be a cause and a consequence of affective experiences. However, daily longitudinal studies show sleep assessed via sleep diaries is more consistently associated with positive and negative affect than sleep assessed via actigraphy. The objective of the study was to test whether sleep parameters derived from ambulatory electroencephalography (EEG) in a naturalistic setting were associated with day-to-day changes in affect. Read More

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Role of Video-EEG in Children.

Indian J Pediatr 2021 Jan 4. Epub 2021 Jan 4.

Department of Neurology and Epileptology, Advanced Center for Epilepsy, Gleneagles Global Health City, Perumbakkam, Chennai, 600100, India.

Routine electroencephalogram (EEG) has many limitations, especially the inability to capture reported habitual events in question. A prolonged EEG with synchronized video (video-EEG) overcomes some of these limitations by improving the sensitivity, specificity and the diagnostic yield by attempting to record the habitual events when they are frequent and when indicated. Video-EEG is employed commonly for the diagnosis and classification of epilepsy/epilepsy syndromes, to distinguish between seizures and seizures mimickers, for pre-surgical evaluation and in the management of critically ill children. Read More

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January 2021

Performance of an ambulatory electroencephalogram sleep monitor in patients with psychiatric disorders.

J Sleep Res 2020 Dec 28:e13273. Epub 2020 Dec 28.

Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Key clinical symptoms observed among individuals with psychiatric disorders include difficulty falling asleep or maintaining sleep, poor sleep quality and nightmares. Those suffering from sleep disorders often present with symptoms of discontent with regard to sleep quality, timing and quantity, and these symptoms have an adverse impact on function and quality of life. A minimally invasive technique would be preferable in patients with psychiatric disorders, who tend to be sensitive to environmental change. Read More

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December 2020

Spatiotemporal Patterns of High-Frequency Activity (80-170 Hz) in Long-Term Intracranial EEG.

Neurology 2021 02 22;96(7):e1070-e1081. Epub 2020 Dec 22.

From the Department of Biomedical Engineering (Z.C., D.B.G., A.N.B., P.J.K, M.J.C.), and Department of Medicine (Z.C., D.B.G., U.S., W.J.D., K.D., M.J.C., M.I.M.), St Vincent's Hospital, Department of Medicine (C.F.), Royal Melbourne Hospital, and Graeme Clark Institute (P.J.K., M.J.C.), The University of Melbourne, VIC, Australia; Cadence Neuroscience (K.L.), Redmond, WA; and 6 Seer Medical (M.I.M.), Melbourne, VIC, Australia.

Objective: To determine the utility of high-frequency activity (HFA) and epileptiform spikes as biomarkers for epilepsy, we examined the variability in their rates and locations using long-term ambulatory intracranial EEG (iEEG) recordings.

Methods: This study used continuous iEEG recordings obtained over an average of 1.4 years from 15 patients with drug-resistant focal epilepsy. Read More

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February 2021

Seizure symptoms and ambulatory EEG findings: incidence of epileptiform discharges.

Epileptic Disord 2020 Dec;22(6):752-758

Neurological Institute, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.

Aims: Ambulatory video-EEG monitoring has been utilized as a cost-effective alternative to inpatient video-EEG monitoring for non-surgical diagnostic evaluation of symptoms suggestive of epileptic seizures. We aimed to assess incidence of epileptiform discharges in ambulatory video-EEG recordings according to seizure symptom history obtained during clinical evaluation.

Methods: This was a retrospective cohort study. Read More

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December 2020

The role of short-term video electroencephalogram monitoring for epilepsy and psychogenic seizures: Experience from a Latin American referral center.

J Clin Neurosci 2020 Dec 5;82(Pt A):105-110. Epub 2020 Nov 5.

Neurophysiology Department, Instituto Nacional de Neurologia y Neurocirugia, Mexico City, Mexico.

Short-term VEEG represents an affordable option in limited resources environments. There are few reports on its use. Its diagnostic yield is variable (7-57%) and can be related to the differences in recording time. Read More

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December 2020

Modulation of locomotor behaviors by location-specific epileptic spiking and seizures.

Epilepsy Behav 2021 01 10;114(Pt A):107652. Epub 2020 Dec 10.

Department of Neurology and Rehabilitation, University of Illinois at Chicago, Chicago, IL, USA; Department of Bioengineering, University of Illinois at Chicago, Chicago, IL, USA. Electronic address:

Introduction: Epilepsy is a debilitating neurological condition characterized by spontaneous seizures as well as significant comorbid behavioral abnormalities. In addition to seizures, epileptic patients exhibit interictal spikes far more frequently than seizures, often, but not always observed in the same brain areas. The exact relationship between spiking and seizures as well as their respective effects on behavior are not well understood. Read More

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January 2021