1,396 results match your criteria Ambulatory EEG

Combining cardiac monitoring with actigraphy aids nocturnal arousal detection during ambulatory sleep assessment in insomnia.

Sleep 2022 May;45(5)

Netherlands Institute for Neuroscience, Department of Sleep and Cognition, Amsterdam, The Netherlands.

Study Objectives: The objective assessment of insomnia has remained difficult. Multisensory devices collecting heart rate (HR) and motion are regarded as the future of ambulatory sleep monitoring. Unfortunately, reports on altered average HR or heart rate variability (HRV) during sleep in insomnia are equivocal. Read More

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Automated seizure detection with non-invasive wearable devices: A systematic review and meta-analysis.

Epilepsia 2022 May 11. Epub 2022 May 11.

Department of Neuroscience, Central Clinical School, Monash University, Melbourne, 3004, Victoria, Australia.

Objective: To review the reported performance of non-invasive wearable devices in detecting epileptic seizures and psychogenic non-epileptic seizures (PNES).

Methods: We conducted a systematic review and meta-analysis of studies reported up to November 15, 2021. We included studies that used video-EEG monitoring as the gold standard to determine the sensitivity and false alarm rate (FAR) of non-invasive wearables for automated seizure detection. Read More

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Acute physiologic prediction of pediatric post-traumatic epilepsy.

Epilepsy Res 2022 Apr 27;183:106935. Epub 2022 Apr 27.

Barrow Neurological Institute at Phoenix Children's Hospital, 1919 E. Thomas Road, Ambulatory Building, 3rd Floor, Phoenix, AZ 85016, USA. Electronic address:

Objective: Post-traumatic epilepsy (PTE) is a known complication of traumatic brain injury (TBI). Limited physiologic biomarkers have been investigated in relation to pediatric PTE. Our aim is to identify clinical, physiologic and neuroimaging biomarkers predictive of pediatric PTE arising during the acute care phase after injury. Read More

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Dissociable changes in sleep architecture with mindfulness and sleep hygiene intervention in older adults: secondary and exploratory analysis of polysomnography data from the Mindfulness Sleep Therapy (MIST) trial.

Sleep Health 2022 Apr 25. Epub 2022 Apr 25.

Centre for Sleep and Cognition, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Department of Psychology, National University of Singapore, Singapore. Electronic address:

Objectives: We conducted a secondary analysis of the Mindfulness Sleep Therapy study, a randomized controlled trial testing Mindfulness-Based Therapy for Insomnia (MBTI) against a sleep hygiene education and exercise program (SHEEP). We investigated whether the interventions led to changes in sleep macroarchitecture (N2, N3 and REM), and microarchitecture (sleep fragmentation, slow wave activity, spectral band power) measured by ambulatory polysomnography (PSG).

Methods: 48 MBTI and 46 SHEEP participants provided usable PSG and subjective sleep quality data both pre- and post intervention. Read More

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Validation of Continuous Monitoring System for Epileptic Users in Outpatient Settings.

Sensors (Basel) 2022 Apr 9;22(8). Epub 2022 Apr 9.

Neuroengineering Biomedical Research Group, Miguel Hernández University of Elche, 03202 Elche, Spain.

Epilepsy is a chronic disease with a significant social impact, given that the patients and their families often live conditioned by the possibility of an epileptic seizure and its possible consequences, such as accidents, injuries, or even sudden unexplained death. In this context, ambulatory monitoring allows the collection of biomedical data about the patients' health, thus gaining more knowledge about the physiological state and daily activities of each patient in a more personalized manner. For this reason, this article proposes a novel monitoring system composed of different sensors capable of synchronously recording electrocardiogram (ECG), photoplethysmogram (PPG), and ear electroencephalogram (EEG) signals and storing them for further processing and analysis in a microSD card. Read More

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Deep Learning Enabled Diagnosis of Children's ADHD Based on the Big Data of Video Screen Long-Range EEG.

J Healthc Eng 2022 4;2022:5222136. Epub 2022 Apr 4.

Department of Electrophysiology, Huizhou No. 2 Maternal and Child Health Hospital, Huizhou, Guangdong 561000, China.

Attention-deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder in children. At the same time, ADHD is prone to coexist with other mental disorders, so the diagnosis of ADHD in children is very important. Electroencephalogram (EEG) is the sum of the electrical activity of local neurons recorded from the extracranial scalp or intracranial. Read More

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Combining cardiac monitoring with actigraphy aids nocturnal arousal detection during ambulatory sleep assessment in insomnia.

Sleep 2022 Mar 31. Epub 2022 Mar 31.

Netherlands Institute for Neuroscience, Department of Sleep and Cognition, Amsterdam, The Netherlands.

Study Objectives: The objective assessment of insomnia has remained difficult. Multisensory devices collecting heart rate (HR) and motion are regarded as the future of ambulatory sleep monitoring. Unfortunately, reports on altered average HR or heart rate variability (HRV) during sleep in insomnia are equivocal. Read More

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Generalized Fast Discharges Along the Genetic Generalized Epilepsy Spectrum: Clinical and Prognostic Significance.

Front Neurol 2022 10;13:844674. Epub 2022 Mar 10.

Epilepsy Unit, Department of Human Neurosciences, Policlinico "Umberto I", Sapienza University, Rome, Italy.

Objective: To investigate the electroclinical characteristics and the prognostic impact of generalized fast discharges in a large cohort of genetic generalized epilepsy (GGE) patients studied with 24-h prolonged ambulatory electroencephalography (paEEG).

Methods: This retrospective multicenter cohort study included 202 GGE patients. The occurrence of generalized paroxysmal fast activity (GPFA) and generalized polyspike train (GPT) was reviewed. Read More

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Event-related potential studies of emotion regulation: A review of recent progress and future directions.

Int J Psychophysiol 2022 Jun 25;176:73-88. Epub 2022 Mar 25.

Department of Medicine, MSB Medical School Berlin, Berlin, Germany.

Event-related potentials (ERPs) bring many strengths to the study of emotion regulation, including: direct measurement of neural activity, high temporal resolution, affordability and suitability to a wide range of participants. Research using ERPs to study emotion regulation began approximately two decades ago, but has grown exponentially over the last 10 years. Here, we highlight progress in this body of work throughout the past decade, as well as emerging themes, novel approaches and paradigms that will likely shape the field in the coming years. Read More

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A Prospective Randomized Controlled Trial: Alternative Approach to EEG Application to Reduce Electrode-induced Skin Injury among Ambulatory EEG Patients.

Neurodiagn J 2022 Mar;62(1):37-51

Faculty of Medicine & Health University of Sydney Sydney, Australia.

Ambulatory electroencephalography (AEEG) is a technique of continuous EEG recording of patients in their natural setting, outside the controlled environment of the hospital. Electrode-induced skin injury is a common complication of prolonged EEG monitoring. This randomized study aimed to investigate the performance of two methods of electrode application in reducing electrode-induced skin injury among patients undergoing 4-day AEEG monitoring. Read More

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Late-Onset Focal Epilepsy: Electroclinical Features and Prognostic Role of Leukoaraiosis.

Front Neurol 2022 23;13:828493. Epub 2022 Feb 23.

Epilepsy Center, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Mondino Foundation, Pavia, Italy.

The aim of this study was to describe the electroclinical and prognostic characteristics, and to investigate the role of leukoaraiosis in outpatients with new-onset elderly focal epilepsy aged ≥60 years, referred to a tertiary epilepsy center between 2005 and December 31, 2020. Among the 720 patients who were referred to the center, we retrospectively selected 162 consecutive outpatients, with a first referral for recent-onset focal epilepsy of unknown cause (UC) or structural cause (SC), and collected a clinical and standard-Electroencephalogram (S-EEG), 24-h ambulatory EEG (A-EEG), and neuroimaging data. We also analyzed the seizure prognosis after titration of the first antiseizure medication (ASM). Read More

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February 2022

A multimodal AI system for out-of-distribution generalization of seizure identification.

IEEE J Biomed Health Inform 2022 Mar 9;PP. Epub 2022 Mar 9.

Artificial intelligence (AI) and health sensory data-fusion hold the potential to automate many laborious and time-consuming processes in hospitals or ambulatory settings, e.g. home monitoring and telehealth. Read More

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Sleep alterations are related to cognitive symptoms in Parkinson's disease: A 24-hour ambulatory polygraphic EEG study.

Int J Psychophysiol 2022 03 22;173:93-103. Epub 2022 Jan 22.

National Institute of Mental Health, Neurology and Neurosurgery, Department of Neurology, 57 Amerikai út, Budapest 1145, Hungary; Semmelweis University, Department of Neurology, 6 Balassa utca, Budapest 1083, Hungary.

Background: Sleep disorders are frequent and early non-motor symptoms of Parkinson's disease (PD). As a consequence of histopathological changes, the regulation of rapid eye movement (REM) sleep is affected in PD causing REM sleep behaviour disorder in about half of the patients. Considering the well-known role of sleep in memory formation processes, our aim was to investigate the relationship between sleep alterations and cognitive performance to elucidate the possible association between sleep, and especially REM sleep changes and cognitive dysfunction in PD. Read More

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Electrical brain stimulation and continuous behavioral state tracking in ambulatory humans.

J Neural Eng 2022 02 8;19(1). Epub 2022 Feb 8.

Bioelectronics Neurophysiology and Engineering Laboratory, Department of Neurology, Mayo Clinic, Rochester, MN, United States of America.

Electrical deep brain stimulation (DBS) is an established treatment for patients with drug-resistant epilepsy. Sleep disorders are common in people with epilepsy, and DBS may actually further disturb normal sleep patterns and sleep quality. Novel implantable devices capable of DBS and streaming of continuous intracranial electroencephalography (iEEG) signals enable detailed assessments of therapy efficacy and tracking of sleep related comorbidities. Read More

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February 2022

Accelerated long-term forgetting in adult patients with genetic generalized epilepsy.

Epilepsia 2022 02 10;63(2):474-482. Epub 2021 Dec 10.

Center for Neurology, Vilnius University, Vilnius, Lithuania.

Objective: Accelerated long-term forgetting (ALF) has been demonstrated among children but not adults with genetic generalized epilepsy (GGE). We investigated (1) how forgetting patterns of verbal and visuospatial material differ between patients with GGE and healthy controls (HCs) and (2) whether ALF is associated with ictal or interictal epileptic activity.

Methods: Forty-two patients with GGE (39, 92. Read More

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February 2022

A comparative study of AI systems for epileptic seizure recognition based on EEG or ECG.

Annu Int Conf IEEE Eng Med Biol Soc 2021 11;2021:2191-2196

The majority of studies for automatic epileptic seizure (ictal) detection are based on electroencephalogram (EEG) data, but electrocardiogram (ECG) presents a simpler and more wearable alternative for long-term ambulatory monitoring. To assess the performance of EEG and ECG signals, AI systems offer a promising way forward for developing high performing models in securing both a reasonable sensitivity and specificity. There are crucial needs for these AI systems to be developed with more clinical relevance and inference generalization. Read More

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November 2021

DBS of Thalamic Centromedian Nucleus for Lennox-Gastaut Syndrome (ESTEL Trial).

Ann Neurol 2022 02 28;91(2):253-267. Epub 2021 Dec 28.

Department of Medicine (Austin Health), University of Melbourne, Heidelberg, VIC, Australia.

Objective: Prior uncontrolled studies have reported seizure reductions following deep brain stimulation (DBS) in patients with Lennox-Gastaut syndrome (LGS), but evidence from randomized controlled studies is lacking. We aimed to formally assess the efficacy and safety of DBS to the centromedian thalamic nucleus (CM) for the treatment of LGS.

Methods: We conducted a prospective, double-blind, randomized study of continuous, cycling stimulation of CM-DBS, in patients with LGS. Read More

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February 2022

Interictal Activity Is Associated With Slower Binocular Rivalry in Idiopathic Generalized Epilepsy.

Front Neurol 2021 10;12:720126. Epub 2021 Nov 10.

Department of Neurology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.

Perceptual alternations evoked by binocular rivalry (BR) reflect cortical dynamics strongly dependent on the excitatory-inhibitory balance, suggesting potential utility as a biomarker for epileptogenesis. Therefore, we investigated the characteristics of BR in patients with idiopathic generalized epilepsy (IGE) and potential associations with clinical variables. Sixty-two healthy controls (HCs) and 94 IGE patients completed BR task. Read More

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November 2021

High prevalence of pathological alertness and wakefulness on maintenance of wakefulness test in adults with focal-onset epilepsy.

Epilepsy Behav 2021 12 17;125:108400. Epub 2021 Nov 17.

Department of Neurology, University of New Mexico, Albuquerque, NM, United States.

Background: Excessive daytime sleepiness (EDS) is a common complaint in adults with epilepsy (AWE), but objective evaluation is lacking. We used the maintenance of wakefulness test (MWT) to objectively measure the ability of adults with focal-onset epilepsy to maintain wakefulness in soporific conditions.

Methods: Adults with epilepsy participating in a study investigating the effects of lacosamide on sleep and wakefulness underwent baseline ambulatory polysomnography (PSG)/EEG followed by MWT. Read More

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December 2021

A high-density 256-channel cap for dry electroencephalography.

Hum Brain Mapp 2022 03 19;43(4):1295-1308. Epub 2021 Nov 19.

Institute of Biomedical Engineering and Informatics, Technische Universität Ilmenau, Ilmenau, Germany.

High-density electroencephalography (HD-EEG) is currently limited to laboratory environments since state-of-the-art electrode caps require skilled staff and extensive preparation. We propose and evaluate a 256-channel cap with dry multipin electrodes for HD-EEG. We describe the designs of the dry electrodes made from polyurethane and coated with Ag/AgCl. Read More

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On effective cognitive state classification using novel feature extraction strategies.

Cogn Neurodyn 2021 Dec 22;15(6):1125-1155. Epub 2021 Jun 22.

Machine Intelligence and Bio-Motion Research Lab, Department of Computer Science and Engineering, NIT Rourkela, Rourkela, Odisha India.

Investigating new features for human cognitive state classification is an intiguing area of research with Electroencephalography (EEG) based signal analysis. We plan to develop a cost-effective system for cognitive state classification using ambulatory EEG signals. A novel event driven environment is created using external stimuli for capturing EEG data using a 14-channel Emotiv neuro-headset. Read More

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December 2021

Ambulatory EEG: Crossing the divide during a pandemic.

Epilepsy Behav Rep 2021 10;16:100500. Epub 2021 Nov 10.

Department of Neurology, Mayo Clinic, Jacksonville, FL, USA.

The COVID-19 pandemic forced temporary closure of epilepsy monitoring units across the globe due to potential hospital-based contagion. As COVID-19 exposures and deaths continues to surge in the United States and around the world, other types of long-term EEG monitoring have risen to fill the gap and minimize hospital exposure. AEEG has high yield compared to standard EEG. Read More

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November 2021

Driving-Induced Neurological Biomarkers in an Advanced Driver-Assistance System.

Sensors (Basel) 2021 Oct 21;21(21). Epub 2021 Oct 21.

Center for Medical Convergence Metrology, Korea Research Institute of Standards and Science, Daejeon 34113, Korea.

Physiological signals are immediate and sensitive to neurological changes resulting from the mental workload induced by various driving environments and are considered a quantifying tool for understanding the association between neurological outcomes and driving cognitive workloads. Neurological assessment, outside of a highly-equipped clinical setting, requires an ambulatory electroencephalography (EEG) headset. This study aimed to quantify neurological biomarkers during a resting state and two different scenarios of driving states in a virtual driving environment. Read More

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October 2021

Brainwaves beyond diagnosis: Wider applications of electroencephalography in idiopathic generalized epilepsy.

Epilepsia 2022 01 10;63(1):22-41. Epub 2021 Nov 10.

Department of Neuroscience, St. Vincent's Hospital, University of Melbourne, Melbourne, Victoria, Australia.

Electroencephalography (EEG) has long been used as a versatile and noninvasive diagnostic tool in epilepsy. With the advent of digital EEG, more advanced applications of EEG have emerged. Compared with technologically advanced practice in focal epilepsies, the utilization of EEG in idiopathic generalized epilepsy (IGE) has been lagging, often restricted to a simple diagnostic tool. Read More

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January 2022

Ambulatory seizure forecasting with a wrist-worn device using long-short term memory deep learning.

Sci Rep 2021 11 9;11(1):21935. Epub 2021 Nov 9.

Departments of Neurology and Biomedical Engineering, Mayo Foundation, Rochester, MN, USA.

The ability to forecast seizures minutes to hours in advance of an event has been verified using invasive EEG devices, but has not been previously demonstrated using noninvasive wearable devices over long durations in an ambulatory setting. In this study we developed a seizure forecasting system with a long short-term memory (LSTM) recurrent neural network (RNN) algorithm, using a noninvasive wrist-worn research-grade physiological sensor device, and tested the system in patients with epilepsy in the field, with concurrent invasive EEG confirmation of seizures via an implanted recording device. The system achieved forecasting performance significantly better than a random predictor for 5 of 6 patients studied, with mean AUC-ROC of 0. Read More

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November 2021

Home (Level 2) polysomnography is feasible in children with suspected sleep disorders.

Sleep Med 2021 12 22;88:157-161. Epub 2021 Oct 22.

Queensland Children's Lung and Sleep Specialists, Australia. Electronic address:

Aim: To audit the feasibility and patient experience of home polysomnography (sleep study) for the investigation of a sleep disorder in children.

Methods: The signal quality and outcomes of a Level 2 (home) polysomnography in young people undergoing investigation between September 2020 and January 2021 in a single centre was reviewed. A successful home polysomnogram was defined as a study with ≥6 h of sleep and all channels (EEG, thoraco-abdominal bands, calculated airflow, and pulse oximetry) present for at least 90% of the study time. Read More

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December 2021

Application of Responsive Neurostimulation as both a Diagnostic Tool for Seizure Localization and a Supplementary Tool for Surgical Management in Patients with Multiple Epileptogenic Foci: A Case Series.

Turk Neurosurg 2022 ;32(1):112-121

University of California, Irvine Medical Center, Department of Neurological Surgery, Orange, CA, USA.

Aim: To present a series of medically refractory focal epilepsy patients with multiple or eloquent epileptogenic zones (EZs) in whom a responsive neurostimulation (RNS) system was used as a complementary modality to surgical resection. RNS was also used as a diagnostic tool to monitor long-term epileptogenic activity for enhanced localization, especially in patients with bilateral temporal seizures.

Material And Methods: Ten consecutive patients who underwent RNS system placement and surgical resection at a single institution were assessed. Read More

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January 2022

Medical Technology: A Systematic Review on Medical Devices Utilized for Epilepsy Prediction and Management.

Curr Neuropharmacol 2022 ;20(5):950-964

Neuropharmacology Research Laboratory, Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Bandar Sunway, Selangor, Malaysia.

Background: Epilepsy is a devastating neurological disorder that affects nearly 70 million people worldwide. Epilepsy causes uncontrollable, unprovoked and unpredictable seizures that reduce the quality of life of those afflicted, with 1-9 epileptic patient deaths per 1000 patients occurring annually due to sudden unexpected death in epilepsy (SUDEP). Predicting the onset of seizures and managing them may help patients from harming themselves and may improve their well-being. Read More

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January 2022

Integrated Gait Triggered Mixed Reality and Neurophysiological Monitoring as a Framework for Next-Generation Ambulatory Stroke Rehabilitation.

IEEE Trans Neural Syst Rehabil Eng 2021 25;29:2435-2444. Epub 2021 Nov 25.

Brain stroke affects millions of people in the world every year, with 50 to 60 percent of stroke survivors suffering from functional disabilities, for which early and sustained post-stroke rehabilitation is highly recommended. However, approximately one third of stroke patients do not receive early in hospital rehabilitation programs due to insufficient medical facilities or lack of motivation. Gait triggered mixed reality (GTMR) is a cognitive-motor dual task with multisensory feedback tailored for lower-limb post-stroke rehabilitation, which we propose as a potential method for addressing these rehabilitation challenges. Read More

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December 2021

Bilateral temporal lobe epilepsy: How many seizures are required in chronic ambulatory electrocorticography to estimate the laterality ratio?

Epilepsia 2022 01 1;63(1):199-208. Epub 2021 Nov 1.

Department of Neurology and Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, California, USA.

Objective: This study was undertaken to measure the duration of chronic electrocorticography (ECoG) needed to attain stable estimates of the seizure laterality ratio in patients with drug-resistant bilateral temporal lobe epilepsy (BTLE).

Methods: We studied 13 patients with drug-resistant BTLE who were implanted for at least 1 year with a responsive neurostimulation device (RNS System) that provides chronic ambulatory ECoG. Bootstrap analysis and nonlinear regression were applied to model the relationship between chronic ECoG duration and the probability of capturing at least one seizure. Read More

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January 2022