Search Our Scientific Publications & Authors

Ocul Immunol Inflamm 2021 Jun 11:1-3. Epub 2021 Jun 11.

Jhaveri Microbiology Centre, LV Prasad Eye Institute, Hyderabad, India.

: To report a rare ocular presentation of unilateral anterior uveitis with hypopyon in a 5-year-old child, suspected as masquerade. Retrospective report A 5-year-old boy presented with hypopyon-uveitis. Detailed systemic work-up was negative for masquerade and uveitis entities. Read More

Curr Eye Res 2021 Jun 10. Epub 2021 Jun 10.

Joint Shantou International Eye Center, Shantou University & the Chinese University of Hong Kong, Shantou, China,515041.

Purpose: To quantitatively compare reflectivity and other morphological changes of the photoreceptors of normal eyes with amblyopic eyes using the longitudinal reflectance profile (LRP) on swept-source optical coherence tomography (SS-OCT) images in children and adolescents with unilateral high myopia. The relationships between OCT parameters and visual acuity were investigated.

Method: Twenty-six amblyopes with unilateral high myopia and 34 age-, axial length- and spherical equivalent-matched normal controls were recruited. Read More

BMC Ophthalmol 2021 Jun 9;21(1):255. Epub 2021 Jun 9.

Department of Ophthalmology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.

Background: Previous studies have demonstrated that strabismus amblyopia can result in markedly brain function alterations. However, the differences in spontaneous brain activities of strabismus amblyopia (SA) patients still remain unclear. Therefore, the current study intended to employthe voxel-mirrored homotopic connectivity (VMHC) method to investigate the intrinsic brain activity changes in SA patients. Read More

Ann Palliat Med 2021 May;10(5):5619-5626

Shenzhen Eye Hospital, Shenzhen Eye Hospital affiliated to Jinan University, School of Optometry, Shenzhen University, Shenzhen, China.

Background: To evaluate the visual outcome and complications of surgical membranectomy with modified incision and capsulotomy microscissors in patients with persistent pupillary membrane (PPM).

Methods: We enrolled eight eyes with PPM in six patients and performed surgical membranectomy with modified incision located near the limbus and corresponding to the middle of the densest membrane strands. Strands near the collarette of the iris were then cut using capsulotomy microscissors and thick strands were removed with capculorhexis forceps. Read More

Pak J Med Sci 2021 May-Jun;37(3):746-750

Dr. Omar Zafar, MCPS, FCPS., Armed Forces Institute of Ophthalmology, Rawalpindi, Pakistan.

Objective: To highlight the prevalence of incidentally discovered ocular findings harvested amongst candidates of different age groups presented for pre-employment screening in a tertiary care eye hospital.

Methods: This Cross sectional prospective study was conducted in Armed Forces Institute of Ophthalmology, Rawalpindi, from Jun 2018 to Dec 2019. Data was collected using non-probability consecutive sampling technique. Read More

BMC Ophthalmol 2021 Jun 8;21(1):254. Epub 2021 Jun 8.

Department of Strabismus and Amblyopia, Affiliated Eye Hospital of Wenzhou Medical University, Hangzhou, 310016, Zhejiang Province, China.

Background: To quantify and compare retinal microvascular features using optical coherence tomography angiography (OCTA) in constant (XT) and intermittent exotropia (IXT).

Methods: An observational cross-sectional study was conducted from September 2020 to November 2020 at the Affiliated Eye Hospital of Wenzhou Medical University. OCTA examination was performed to evaluate the macular perfusion density of the deep capillary plexus (DCP), superficial capillary plexus (SCP), and foveal avascular zone (FAZ) parameters in XT and IXT patients, and in age-matched controls. Read More

Front Pediatr 2021 21;9:620565. Epub 2021 May 21.

Department of Ophthalmology, Jinan 2nd People's Hospital, Jinan, China.

To examine the quantitative measurements of OCTA in children with amblyopia using the meta-analysis methodology. PubMed, Embase, and Cochrane library were searched for available papers up to March 2021. Weighted mean differences (WMD) were used to compare the retina parameters between the eyes with amblyopia and the contralateral eyes or healthy control eyes. Read More

Front Neurosci 2021 20;15:674146. Epub 2021 May 20.

Smith-Kettlewell Eye Research Institute, San Francisco, CA, United States.

Background: Feature counting requires rapid shifts of attention in the visual field and reflects higher-level cortical functions. This process is drastically impaired in the amblyopic eye of strabismic amblyopes. In this study, we hypothesized that feature counting performance in anisometropic and strabismic amblyopes is further impaired when shifts in attention is required between the eyes. Read More

Saudi J Ophthalmol 2020 Jul-Sep;34(3):209-211. Epub 2021 Feb 27.

Anterior Segment Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.

We report a case of bilateral myelinated nerve fiber layer (MNFL) in a 24-year-old male with high hyperopia and amblyopia. He presented with poor vision bilaterally since childhood and was evaluated for ophthalmic and systemic diseases. Retinal examination indicated MNFLs in both eyes. Read More

Saudi J Ophthalmol 2020 Jul-Sep;34(3):198-201. Epub 2021 Feb 27.

King Abdullah International Medical Research Center, King Abdulaziz Medical City, Jeddah, Saudi Arabia.

Arab and Muslim scientists were pioneers in the development of medical sciences, treating patients, and performing operations in many medical specialties. This article reviews their major contributions in ophthalmology that led to the development of this field. Considering the little-known role of Arab and Muslim scientists in the history of ophthalmology, this article provide insights into the great physicians from the 10th to the 13th century. Read More

Saudi J Ophthalmol 2020 Jul-Sep;34(3):186-190. Epub 2021 Feb 27.

Department of Optometry, Faculty of Applied Medical Science, University of Jeddah, Jeddah, Saudi Arabia.

Purpose: This study aimed to determine whether the plusoptiX vision screener (PVS) can be used to detect amblyogenic risk factors (ARFs) as defined by the American Association for Paediatric Ophthalmology and Strabismus Vision Screening Committee guidelines (2013) for automated vision screening devices.

Methods: In this cross-sectional study, children attending a special needs school underwent screening with the PVS and complete ophthalmologic examinations. Ophthalmologic examinations were used as the gold standard to compute the prevalence, sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and testability. Read More

Saudi J Ophthalmol 2020 Jul-Sep;34(3):171-176. Epub 2021 Feb 27.

Departments of Ophthalmology, College of Medicine, Al Imam Mohammad Ibn Saud Islamic University, King Khalid Eye Specialist Hospital, Saudi Residency Training Program in Preventive Medicine, Ministry of Health, Riyadh, Saudi Arabia.

Purpose: The current study aimed to assess Saudi parents' awareness regarding pediatric eye diseases that can be screened and treated.

Methods: A cross-sectional study was conducted in Riyadh, Saudi Arabia. Targeted participants were selected randomly. Read More

J Curr Ophthalmol 2021 Jan-Mar;33(1):31-35. Epub 2021 Mar 26.

Department of Ophthalmology, Nikookari Eye Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.

Purpose: To evaluate the efficacy of three-muscle surgery for the treatment of large-angle exotropia with particular attention to the success rate and mean dose-response ratio.

Methods: In a retrospective study, medical records were reviewed for 48 patients with exodeviation between 50 and 80 prism diopter (PD) who underwent bilateral lateral rectus recession as well as one medial rectus resection. Sex, age at surgery, presence of amblyopia, amount of preoperative and postoperative deviation, total amount of recessed and resected muscles, dose-response ratio, and associated vertical deviations were analyzed. Read More

Oman J Ophthalmol 2021 Jan-Apr;14(1):38-41. Epub 2021 Feb 27.

Department of Pediatric Ophthalmology, Sankara Nethralaya, Chennai, Tamil Nadu, India.

Aims: The purpose of this study is to describe the clinical profile of children presenting with posterior lenticonus. We also report on visual outcomes following surgery in these patients.

Subjects And Methods: Medical records of patients with a diagnosis of posterior lenticonus between January 2000 and December 2016 were reviewed. Read More

Oman J Ophthalmol 2021 Jan-Apr;14(1):14-19. Epub 2021 Feb 27.

Department of Ophthalmology, Dr. D. Y. Patil Medical College Hospital, Pune, Maharashtra, India.

Background: The preschool children hardly complain about their vision problems. It is of paramount importance to screen them with an objective tool and compare with the gold standard technique.

Aim: To compare the values obtained with Plusoptix A09 and cycloplegic refraction in 3-6 years children and agreement to detect refractive amblyogenic risk factors. Read More

J AAPOS 2021 May 31. Epub 2021 May 31.

Department of Health Sciences Research, Mayo Clinic, Jacksonville, Florida.

Purpose: To report the prevalence of subclinical markers of strabismus from a community-based screening of children.

Methods: A family history and ophthalmic examination (including six markers of strabismus: oblique muscle dysfunction, stereopsis <60 arcsec, monofixation, nasal-temporal pursuit asymmetry, dissociated strabismus, and anisometropia) were obtained from consecutive children, aged 5-18 years, in the local school system and the pediatric outpatient clinic of Mayo Clinic, Rochester, Minnesota.

Results: A total of 1,000 children (498 males [49. Read More

Front Med (Lausanne) 2021 17;8:619767. Epub 2021 May 17.

Singapore National Eye Centre, Singapore Eye Research Institute, Singapore, Singapore.

The risk of pathologic myopia (PM) increases with worsening myopia and may be related to retinal microvasculature alterations. To evaluate this, we analyzed the macular microvasculature of myopes with swept source-optical coherence tomographic angiography (SS-OCTA) in adolescent and young adult Singaporeans. This is a prevalent case-control study including 93 young Chinese from the Strabismus, Amblyopia and Refractive error in Singaporean children (STARS, = 45) study and the Singapore Cohort Study of Risk Factors for Myopia (SCORM, = 48) studies. Read More

Graefes Arch Clin Exp Ophthalmol 2021 Jun 2. Epub 2021 Jun 2.

Department of Ophthalmology, Seoul National University Hospital, Seoul, Republic of Korea.

Purpose: We evaluated the long-term visual outcomes in children with primary congenital glaucoma and determined the factors associated with the final visual outcomes.

Methods: Medical records of children with primary congenital glaucoma between 2005 and 2016, seen at Seoul National University Children's Hospital in South Korea, were reviewed. The minimum follow-up period after surgery for primary congenital glaucoma was 3 years. Read More

Sci Rep 2021 Jun 1;11(1):11430. Epub 2021 Jun 1.

Institute of Basic Medical Sciences, National Cheng Kung University, Tainan, 701, Taiwan.

Treatment of grating stimulation has been used in amblyopia for decades, but high dropout rate and inconvenience for daily practice occur in previous studies. We developed a home-based portable system with rotating grating stimulation on a tablet. Thirty anisometropic amblyopic children were randomly allocated into the control or Grating group. Read More

Brain Sci 2021 May 18;11(5). Epub 2021 May 18.

Facultad de Ingeniería, Universidad Autónoma de Querétaro, Santiago de Querétaro 76010, Mexico.

This research assesses the brain activity and visual performance at baseline and after light therapy (LTH), of seventeen patients with strabismus and amblyopia (SA), and eleven healthy controls (HCs) from Querétaro, México. Quantitative electroencephalogram analysis (qEEG) was used to record the brain activity, and clinical metrics such as the visual acuity, angle of deviation, phoria state, stereopsis, and visual fields determined the visual performance. Results showed a constant higher alpha-wave frequency for HCs. Read More

Vision (Basel) 2021 May 11;5(2). Epub 2021 May 11.

Eye Clinic, Jessenius Faculty of Medicine, Commenius University in Bratislava, Kollárova 2, 036 59 Martin, Slovakia.

A case of an adult with anisometropic amblyopia who underwent a successful vision therapy program playing videogames in a virtual reality environment is described, reporting changes in conventional visual clinical data, as well as in brain activity. The patient was a 22 year old man on baseline examination that never previously wore correction for his anisometropia. After prescribing contact lens correction for the anisometropia and after 44 h of virtual reality-based vision therapy over a period of 1. Read More

Graefes Arch Clin Exp Ophthalmol 2021 May 31. Epub 2021 May 31.

Department of Ophthalmology, Erasmus Medical Center, Room Ee 1663, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands.

Purpose: In an ongoing randomised clinical trial comparing dichoptic VR video games with patching for amblyopia, we evaluated any potential barriers to successful use of this novel amblyopia treatment method.

Methods: From December 2017, all newly diagnosed amblyopic children were recruited. Excluded were children under age 4 and patients with strabismus exceeding 30PD. Read More

World J Clin Cases 2021 May;9(15):3779-3786

Department of Ophthalmology, The First Affiliated Hospital of Dalian Medical University, Dalian 116001, Liaoning Province, China.

Background: Scleritis is a rare disease and the incidence of bilateral posterior scleritis is even rarer. Unfortunately, misdiagnosis of the latter is common due to its insidious onset, atypical symptoms, and varied manifestations. We report here a case of bilateral posterior scleritis that presented with acute eye pain and intraocular hypertension, and was initially misdiagnosed as acute primary angle closure. Read More

Clin Optom (Auckl) 2021 18;13:143-153. Epub 2021 May 18.

FelegeHiwot Comprehensive Specialized Hospital, Bahir Dar, Ethiopia.

Introduction: Worldwide, amblyopia prevalence among children is in the range of 0.13% to 12.9%. Read More

J Pediatr Ophthalmol Strabismus 2021 May-Jun;58(3):196-201. Epub 2021 May 1.

Purpose: To report the visual outcomes, refractive results, and complications of simple excision for limbal dermoid in the first 8 years of life.

Methods: This retrospective chart review included all children aged 8 years or younger who underwent excision of a grade I or II limbal dermoid without involvement of the visual axis between the years 2000 and 2019.

Results: Nineteen patients met the inclusion criteria. Read More

J Pediatr Ophthalmol Strabismus 2021 May-Jun;58(3):154-160. Epub 2021 May 1.

Purpose: To compare the visual outcome of occlusion therapy with virtual reality game playing as a new therapy for children with amblyopia.

Methods: This randomized clinical trial was performed on 50 children between 4 and 10 years old who had unilateral amblyopia. They were randomly divided into virtual reality and patching groups (n = 25 in each). Read More

J Pediatr Ophthalmol Strabismus 2021 Mar-Apr;58(2):93-104. Epub 2021 Mar 1.

Purpose: To characterize the effects of eye muscle surgery on patients older than 18 years with infantile nystagmus syndrome (INS) who have had only optical treatment.

Methods: This was a prospective, single-center, interventional case series analysis of clinical and electro-phyisological data before and after surgery. Outcome measures included: clinical characteristics, surgical procedure, and preoperative and postoperative binocular best corrected visual acuity (BCVA) in the null position, anomalous head posture (AHP), contrast sensitivity, strabismic deviation, and nystagmus acuity function (NAFX). Read More

BMC Ophthalmol 2021 May 25;21(1):232. Epub 2021 May 25.

Department of Ophthalmology, China Medical University Hospital, China Medical University, 2 Yuh-Der Road, Taichung City, 40447, Taiwan.

Background: Deprivation amblyopia is a great concern in hyperplastic persistent pupillary membranes (PPM) which blocked visual axis. Other ocular abnormality may accompany and further hinder the visual development of the infants. We evaluate the long-term visual prognosis and complications in patients with dense PPM and other associated abnormalities treated with early surgical intervention and timely visual rehabilitation. Read More

Cureus 2021 Apr 18;13(4):e14552. Epub 2021 Apr 18.

Ophthalmology, Nemours Children's Hospital, Orlando, USA.

The case involves a five-year-old female patient with a myelinated retinal nerve fiber (MRNF) layer of the right optic disc. Although this is a rare, benign, and often asymptomatic condition, it is sometimes associated with ocular findings which require early detection and treatment. In this case, the patient presented with strabismus, high myopia, and amblyopia. Read More

Transl Pediatr 2021 Apr;10(4):860-869

Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China.

Background: The syndrome of monocular myelinated retinal nerve fibers (MRNF), myopia and amblyopia threatens visual development of infants and young children. The efficacy of part-time occlusion therapy remains controversial, and the long-term prognosis of the syndrome remains unclear.

Methods: Ten children (4. Read More