16,185 results match your criteria Am J Respir Crit Care Med[Journal]


Reply to Tuffet, et al. and Michard, et al.

Am J Respir Crit Care Med 2020 Jun 3. Epub 2020 Jun 3.

University Hospital Modena, 208968, Respiratory Diseases Unit, Modena, Italy.

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http://dx.doi.org/10.1164/rccm.202005-1730LEDOI Listing

Noninvasive Ventilation for Respiratory Failure: Impact of Ventilator Settings Adjustments.

Am J Respir Crit Care Med 2020 Jun 3. Epub 2020 Jun 3.

Assistance Publique-Hôpitaux de Paris, CHU Henri Mondor, Service de réanimation médicale, Créteil, France.

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http://dx.doi.org/10.1164/rccm.202005-1565LEDOI Listing

Should We Monitor Pulsus Paradoxus via Pulse Oximetry in COVID-19 Patients with Acute Respiratory Failure?

Am J Respir Crit Care Med 2020 Jun 3. Epub 2020 Jun 3.

Yale University, 5755, Anesthesiology, New Haven, Connecticut, United States.

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http://dx.doi.org/10.1164/rccm.202004-1504LEDOI Listing

Pathological Comparisons of Paraseptal and Centrilobular Emphysema in COPD.

Am J Respir Crit Care Med 2020 Jun 2. Epub 2020 Jun 2.

The University of British Columbia Centre for Heart Lung Innovation, 539747, Vancouver, British Columbia, Canada.

Rationale: While centrilobular (CLE) and paraseptal (PSE) emphysema are commonly identified on multi-detector computed tomography (MDCT), little is known about the pathology associated with PSE compared to CLE.

Objective: To assess the pathological differences between PSE and CLE in chronic obstructive pulmonary disease (COPD).

Methods: Air-inflated frozen lung specimens (n=6) obtained from patients with severe COPD treated by lung transplantation were scanned with MDCT. Read More

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http://dx.doi.org/10.1164/rccm.201912-2327OCDOI Listing

A Role for the Rho-GTPase Pathway in Pediatric Obese Asthma.

Authors:
Sunita Sharma

Am J Respir Crit Care Med 2020 Jun 1. Epub 2020 Jun 1.

University of Colorado Denver School of Medicine, 12225, Department of Medicine, Aurora, Colorado, United States;

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http://dx.doi.org/10.1164/rccm.202004-1073EDDOI Listing

Respiratory Mechanics of COVID-19 Non-COVID-19 Associated Acute Respiratory Distress Syndrome.

Am J Respir Crit Care Med 2020 Jun 1. Epub 2020 Jun 1.

Assistance Publique-Hôpitaux de Paris, CHU Henri Mondor, Service de réanimation médicale, Créteil, France.

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http://dx.doi.org/10.1164/rccm.202004-1226LEDOI Listing

Evidence for Exacerbation-Prone Asthma and Predictive Biomarkers of Exacerbation Frequency.

Am J Respir Crit Care Med 2020 Jun 1. Epub 2020 Jun 1.

University of Wisconsin, Medicine-Allergy, Pulmonary and Critical Care Medicine, Madison, Wisconsin, United States.

Background: Cross-sectional studies suggest an exacerbation-prone asthma (EPA) phenotype and the utility of blood eosinophils and plasma interleukin 6 (IL-6) as predictive biomarkers.

Objective: To prospectively test for EPA phenotype and utility of baseline blood measures of eosinophils and IL6 as predictive biomarkers.

Methods: Three-year asthma exacerbation data were analyzed in 406 adults in the Severe Asthma Research Program-3. Read More

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http://dx.doi.org/10.1164/rccm.201909-1813OCDOI Listing

Smoking Pattern in Men and Women: A Possible Contributor to Gender Differences in Smoke-related Lung Diseases.

Am J Respir Crit Care Med 2020 Jun 1. Epub 2020 Jun 1.

Asthma and Airway Disease Research Center, University of Arizona , Medicine, Tucson, Arizona, United States.

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http://dx.doi.org/10.1164/rccm.202004-1472LEDOI Listing

Detection of Acute Pulmonary Embolism by Electrical Impedance Tomography and Saline Bolus Injection.

Am J Respir Crit Care Med 2020 May 29. Epub 2020 May 29.

Furtwangen University, Institute of Technical Medicine, Villingen-Schwenningen, Germany.

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http://dx.doi.org/10.1164/rccm.202003-0554IMDOI Listing

Insights into Critical Care and Post ICU Opiate Administration.

Authors:
Yoanna Skrobik

Am J Respir Crit Care Med 2020 May 28. Epub 2020 May 28.

McGill University, Medicine, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1164/rccm.202005-1815EDDOI Listing

Reply to: TMEM16A Potentiation: Possible Drawbacks.

Am J Respir Crit Care Med 2020 May 28. Epub 2020 May 28.

Enterprise Therapeutics Ltd, 484604, Brighton, United Kingdom of Great Britain and Northern Ireland;

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http://dx.doi.org/10.1164/rccm.202004-1214LEDOI Listing

TMEM16A Potentiation: Possible Drawbacks.

Am J Respir Crit Care Med 2020 May 28. Epub 2020 May 28.

Medical University of Graz, Department of Internal Medicine, Division of Pulmonology, Graz, Austria.

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http://dx.doi.org/10.1164/rccm.202004-0887LEDOI Listing

Pre-Procurement Donor Lung Tissue Gene Expression Classifies Primary Graft Dysfunction Risk.

Am J Respir Crit Care Med 2020 May 28. Epub 2020 May 28.

University of Pennsylvania Perelman School of Medicine, 14640, Philadelphia, Pennsylvania, United States.

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http://dx.doi.org/10.1164/rccm.201912-2436LEDOI Listing

Author Reply to: Whither the Bicarbonate Era.

Am J Respir Crit Care Med 2020 May 27. Epub 2020 May 27.

Universita degli Studi di Milano, 9304, Department of Pathophysiology and Transplantation, Milano, Italy.

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http://dx.doi.org/10.1164/rccm.202005-1842LEDOI Listing

Editorialist's Reply to: Whither the Bicarbonate Era.

Am J Respir Crit Care Med 2020 May 27. Epub 2020 May 27.

University of Pittsburgh, Pittsburgh, Pennsylvania, United States.

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http://dx.doi.org/10.1164/rccm.202005-1747LEDOI Listing

Whither the Bicarbonate Era.

Authors:
Erik R Swenson

Am J Respir Crit Care Med 2020 May 27. Epub 2020 May 27.

VA Medical Center, Seattle, Washington, United States;

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http://dx.doi.org/10.1164/rccm.202005-1544LEDOI Listing

Whole Genome Sequencing Identifies Novel Functional Loci Associated with Lung Function in Puerto Rican Youth.

Am J Respir Crit Care Med 2020 May 27. Epub 2020 May 27.

UC San Francisco, San Francisco, California, United States.

Rationale: Puerto Ricans have the highest childhood asthma prevalence in the United States (23.6%), however, the etiology is uncertain.

Objective: In this study, we sought to uncover the genetic architecture of lung function in Puerto Rican youth with and without asthma who were recruited from the island (n=836). Read More

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http://dx.doi.org/10.1164/rccm.202002-0351OCDOI Listing

Breaking Circular Thinking in the Value of Oxygenation.

Am J Respir Crit Care Med 2020 May 27. Epub 2020 May 27.

Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain.

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http://dx.doi.org/10.1164/rccm.202004-1114LEDOI Listing

Reply to: Breaking Circular Thinking in the Value of Oxygenation.

Authors:
Martin J Tobin

Am J Respir Crit Care Med 2020 May 27. Epub 2020 May 27.

Hines VA Hospital, Pulmonary, Hines, Illinois, United States;

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http://dx.doi.org/10.1164/rccm.202005-1724LEDOI Listing

MRI Evaluation of Regional Lung Tidal Volumes in Severe Neonatal Bronchopulmonary Dysplasia.

Am J Respir Crit Care Med 2020 May 27. Epub 2020 May 27.

Cincinnati Children's Hospital Medical Center, The Perinatal Institute, Cincinnati, Ohio, United States.

Rationale: Bronchopulmonary dysplasia is a heterogeneous lung disease characterized by regions of cysts and fibrosis, but methods for evaluating lung function are limited to whole lung rather than specific regions of interest.

Objective: Respiratory-gated, ultrashort echo time MRI was used to test the hypothesis that cystic regions of the lung will exhibit a quantifiable tidal volume (TV) that will correlate with ventilator settings and clinical outcomes.

Methods: MRI of 17 non-sedated, quiet-breathing, severe bronchopulmonary dysplasia infants were reconstructed into end-inspiration and end-expiration images. Read More

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http://dx.doi.org/10.1164/rccm.202001-0213OCDOI Listing

Localized Tracheal Cryptococcosis Misdiagnosed as Severe Refractory Asthma.

Am J Respir Crit Care Med 2020 May 27. Epub 2020 May 27.

Shonan Fujisawa Tokushukai Hosipital, Respiratory Medicine, Fujisawa-shi, Japan.

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http://dx.doi.org/10.1164/rccm.202001-0032IMDOI Listing

Clarifying the Pulmonary Arterial Hypertension Molecular Landscape Using Functional Genetics.

Authors:
Bradley A Maron

Am J Respir Crit Care Med 2020 May 26. Epub 2020 May 26.

Brigham and Women's Hospital Biomedical Research Institute, 278479, Boston, Massachusetts, United States;

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http://dx.doi.org/10.1164/rccm.202004-1411EDDOI Listing

Metagenomic Characterization of the Respiratory Microbiome: A Pièce de Résistance.

Am J Respir Crit Care Med 2020 May 22. Epub 2020 May 22.

Imperial College, London, National Heart and Lung Institute, London, United Kingdom of Great Britain and Northern Ireland;

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http://dx.doi.org/10.1164/rccm.202005-1686EDDOI Listing

Epithelial Resurfacing: The Bronchial Skin Peel.

Am J Respir Crit Care Med 2020 May 22. Epub 2020 May 22.

Royal Brompton and Harefield NHS Foundation Trust, 4964, London, United Kingdom of Great Britain and Northern Ireland.

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http://dx.doi.org/10.1164/rccm.202004-1097EDDOI Listing

Phenotype and Outcomes of Pulmonary Hypertension Associated with Neurofibromatosis Type 1.

Am J Respir Crit Care Med 2020 May 21. Epub 2020 May 21.

CHU de Bicetre, Service de Pneumologie, Le Kremlin Bicetre, France.

Rationale: Pulmonary hypertension associated with neurofibromatosis type 1 (PH-NF1) is a rare and largely unknown complication of NF1.

Objectives: To describe characteristics and outcomes of PH-NF1.

Methods: We reported the clinical, functional, radiologic, histologic and hemodynamic characteristics, response to pulmonary arterial hypertension (PAH)-approved drugs and transplant-free survival of patients with PH-NF1 from the French PH registry. Read More

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http://dx.doi.org/10.1164/rccm.202001-0105OCDOI Listing

COVID-19, Asthma, and Inhaled Corticosteroids (ICS): Another Beneficial Effect of ICS?

Am J Respir Crit Care Med 2020 May 21. Epub 2020 May 21.

Ghent University Hospital, Respiratory Medicine, GHENT, Belgium;

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http://dx.doi.org/10.1164/rccm.202005-1651EDDOI Listing

Complement Activation During Critical Illness: Current Findings and an Outlook in the Era of COVID-19.

Authors:
Markus Bosmann

Am J Respir Crit Care Med 2020 May 21. Epub 2020 May 21.

Boston University School of Medicine, 12259, Pulmonary Center, Department of Medicine, Boston, Massachusetts, United States.

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http://dx.doi.org/10.1164/rccm.202005-1926EDDOI Listing

Prone Position and Lung Ventilation/Perfusion Matching in Acute Respiratory Failure Due to COVID-19.

Am J Respir Crit Care Med 2020 May 21. Epub 2020 May 21.

Università degli Studi di Padova, 9308, Anesthesia and Intensive Care, Padova, Italy.

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http://dx.doi.org/10.1164/rccm.202003-0775IMDOI Listing
May 2020
12.996 Impact Factor

Home NO Therapy for COVID-19.

Am J Respir Crit Care Med 2020 May 21. Epub 2020 May 21.

University of Pittsburgh Medical Center, Division Chief, Pulmonary, Allergy and Critical Care Medicine, Pittsburgh, Pennsylvania, United States.

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http://dx.doi.org/10.1164/rccm.202005-1906EDDOI Listing

Recommended Reading from the Duke University Pulmonary and Critical Care Medicine Fellows.

Am J Respir Crit Care Med 2020 May 21. Epub 2020 May 21.

Duke University Medical Center, Pulmonary, Allergy, and Critical Care, Durham, North Carolina, United States.

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http://dx.doi.org/10.1164/rccm.201908-1584RRDOI Listing

Protective Mechanical Ventilation in Organ Donors, A Life Saving Maneuver.

Am J Respir Crit Care Med 2020 May 20. Epub 2020 May 20.

Toronto General Hospital, Interdepartmental Division of Critical Care Medicine, Toronto, Ontario, Canada;

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http://dx.doi.org/10.1164/rccm.202005-1559EDDOI Listing

The Dark Side of Spontaneous Breathing During Non-invasive Ventilation: From Hypothesis to Theory.

Authors:
Takeshi Yoshida

Am J Respir Crit Care Med 2020 May 20. Epub 2020 May 20.

Osaka University Hospital, Intensive Care Unit, Suita, Japan.

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http://dx.doi.org/10.1164/rccm.202005-1612EDDOI Listing

Reply to: Are COVID-19 Patients Dying of or with Cardiac Injury?

Am J Respir Crit Care Med 2020 May 20. Epub 2020 May 20.

Chinese PLA General Hospital, 104607, The Second Medical Center & National Clinical Research Center for Geriatric Diseases, Beijing, China;

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http://dx.doi.org/10.1164/rccm.202004-1156LEDOI Listing

Are COVID-19 Patients Dying of or with Cardiac Injury?

Am J Respir Crit Care Med 2020 May 20. Epub 2020 May 20.

University of Thessaly Faculty of Medicine, 37787, Intensive Care Unit, Larissa, Greece.

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http://dx.doi.org/10.1164/rccm.202004-1083LEDOI Listing

Expression of the SARS-CoV-2 Receptor in the Human Airway Epithelium.

Am J Respir Crit Care Med 2020 May 20. Epub 2020 May 20.

Weill Cornell Medical College, New York, New York, United States;

Rationale: Infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease (COVID-19), a predominantly respiratory illness. The first step in SARS-CoV-2 infection is binding of the virus to angiotensin converting enzyme 2 (ACE2) on the airway epithelium.

Objectives: The objective was to gain insight into the expression of ACE2 in the human airway epithelium. Read More

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http://dx.doi.org/10.1164/rccm.202003-0541OCDOI Listing

Platelets Restrict the Oxidative Burst in Phagocytes and Facilitate Primary Progressive Tuberculosis.

Am J Respir Crit Care Med 2020 May 18. Epub 2020 May 18.

Friedrich-Loeffler-Institute Federal Research Institute for Animal Health, 39023, Greifswald - Insel Riems, Germany;

Rationale: Platelets are generated in the capillaries of the lung, control hemostasis and display immunological functions. Tuberculosis primarily affects the lung and patients show platelet changes and hemoptysis. A role of platelets in immunopathology of pulmonary tuberculosis requires careful assessment. Read More

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http://dx.doi.org/10.1164/rccm.201910-2063OCDOI Listing

Recommended Reading from the Virginia Commonwealth University Pulmonary/Critical Care and Interventional Pulmonary Fellows.

Am J Respir Crit Care Med 2020 May 18. Epub 2020 May 18.

Virginia Commonwealth University, 6889, Department of Internal Medicine, Division of Pulmonary Diseases and Critical Care Medicine, Richmond, Virginia, United States;

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http://dx.doi.org/10.1164/rccm.202003-0599RRDOI Listing

Pulmonary Hypertension Complicating Pulmonary Artery Involvement in Pseudoxanthoma Elasticum.

Am J Respir Crit Care Med 2020 May 15. Epub 2020 May 15.

Hopital Bicetre, 41664, Le Kremlin-Bicetre, France.

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http://dx.doi.org/10.1164/rccm.202002-0248IMDOI Listing

Making Medical Treatment Decisions for Unrepresented Patients in the ICU. An Official American Thoracic Society/American Geriatrics Society Policy Statement.

Am J Respir Crit Care Med 2020 May;201(10):1182-1192

: ICU clinicians regularly care for patients who lack capacity, an applicable advance directive, and an available surrogate decision-maker. Although there is no consensus on terminology, we refer to these patients as "unrepresented." There is considerable controversy about how to make treatment decisions for these patients, and there is significant variability in both law and clinical practice. Read More

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http://dx.doi.org/10.1164/rccm.202003-0512STDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7233335PMC

A Case of COVID-19 and Co-infection.

Am J Respir Crit Care Med 2020 May 15. Epub 2020 May 15.

Brigham and Women's Hospital, 1861, Pulmonary and Critical Care Medicine, Boston, Massachusetts, United States;

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http://dx.doi.org/10.1164/rccm.202003-0766LEDOI Listing

Bronchoscopy in COVID-19 Patients with Invasive Mechanical Ventilation: A Center Experience.

Am J Respir Crit Care Med 2020 May 15. Epub 2020 May 15.

Hospital de la Santa Creu i Sant Pau, 16689, Intensive Care, Barcelona, Spain.

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http://dx.doi.org/10.1164/rccm.202004-0945LEDOI Listing

Update in Interstitial Lung Disease 2019.

Am J Respir Crit Care Med 2020 May 15. Epub 2020 May 15.

University of Calgary, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1164/rccm.202002-0360UPDOI Listing

Comment on an American Thoracic Society Public Health Information Series Article.

Authors:

Am J Respir Crit Care Med 2020 Jun;201(11):1453

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http://dx.doi.org/10.1164/rccm.v201comment1DOI Listing

Rifapentine Population Pharmacokinetics and Dosing Recommendations for Latent Tuberculosis Infection.

Am J Respir Crit Care Med 2020 May 15. Epub 2020 May 15.

University of California San Francisco, Bioengineering and Therapeutic Sciences, San Francisco, California, United States;

Rationale: Rifapentine has been investigated at various doses, frequencies, and dosing algorithms but clarity on the optimal dosing approach is lacking.

Objectives: In this individual participant data meta-analysis of rifapentine pharmacokinetics, we characterize rifapentine population pharmacokinetics, including autoinduction, and determine optimal dosing strategies for short-course rifapentine-based regimens for latent tuberculosis infection.

Methods: Rifapentine pharmacokinetic studies were identified though a systematic review of literature. Read More

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http://dx.doi.org/10.1164/rccm.201912-2489OCDOI Listing

Recommended Reading from University of Toronto.

Am J Respir Crit Care Med 2020 May 15. Epub 2020 May 15.

University of Toronto Faculty of Medicine, 12366, Division of Critical Care Medicine, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1164/rccm.201912-2315RRDOI Listing

Update in Chronic Obstructive Pulmonary Disease 2019.

Am J Respir Crit Care Med 2020 May 14. Epub 2020 May 14.

Philipps-Universitat Marburg, Marburg, Germany;

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http://dx.doi.org/10.1164/rccm.202002-0370UPDOI Listing

Bronchial Rheoplasty For Treatment of Chronic Bronchitis: 12 Month Results from a Multi-Center Study.

Am J Respir Crit Care Med 2020 May 14. Epub 2020 May 14.

Gala Therapeutics, Menlo Park, California, United States.

Rationale: Chronic bronchitis is characterized by productive cough with excessive mucus production, resulting in quality of life impairment and increased exacerbation risk. Bronchial Rheoplasty uses an endobronchial catheter to apply non-thermal pulsed electric fields to the airways. Preclinical studies demonstrated epithelial ablation followed by regeneration of normalized epithelium. Read More

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http://dx.doi.org/10.1164/rccm.201908-1546OCDOI Listing

Premature Aging and Increased Risk of Adult Cardiorespiratory Disease After Extreme Preterm Birth: Getting to the Heart (and Lungs) of the Matter.

Am J Respir Crit Care Med 2020 May 14. Epub 2020 May 14.

University of Wisconsin School of Medicine and Public Health, Division of Allergy, Pulmonary and Critical Care, Madison, Wisconsin, United States.

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http://dx.doi.org/10.1164/rccm.202004-1437EDDOI Listing