Ann Phys Rehabil Med 2021 Jan 15;64(1):101430. Epub 2020 Oct 15.
Memory and Aging Center, Global Brain Health Institute, University of California San Francisco, San Francisco, CA, USA; Department of neurology, Memory and Aging center, Sandler Neurosciences Center, University of California San Francisco, San Francisco, CA, USA.
Background: Aging individuals with Down syndrome (DS) are at increased risk of dementia due to trisomy of chromosome 21 on which the amyloid precursor protein gene is located and with increased life expectancy. Yet, little is known about the costs associated with DS dementia and how this compares to Alzheimer's disease (AD).
Objective: To better understand direct healthcare costs and care consumption in DS dementia, we compared the total cost of care to US Medicare and the drivers of these medical expenditures in individuals with DS with and without dementia, and in those with AD without DS. Read More