Chest 2018 10 10;154(4):788-797. Epub 2018 Jul 10.
Department of Respiratory Medicine, University Hospital Zurich, Zurich, Switzerland; Kyrgyz-Swiss High Altitude Clinic and Medical Research Center, Tuja-Ashu, Kyrgyz Republic; Department of Respiratory Medicine, National Center for Cardiology and Internal Medicine, Bishkek, Kyrgyz Republic. Electronic address:
Background: Patients with COPD may experience acute mountain sickness (AMS) and other altitude-related adverse health effects (ARAHE) when traveling to high altitudes. This study evaluated whether dexamethasone, a drug used for the prevention of AMS in healthy individuals, would prevent AMS/ARAHE in patients with COPD.
Methods: This placebo-controlled, double-blind, parallel-design trial included patients with COPD and Global Initiative for Obstructive Lung Disease grade 1 to 2 who were living below 800 m. Read More