Br J Dermatol 2016 Feb 21;174(2):338-47. Epub 2015 Nov 21.
Department of Dermatology, University of Tokyo Graduate School of Medicine, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Background: Endothelial protein C receptor (EPCR), expressed predominantly on endothelial cells, plays a critical role in the regulation of the coagulation system and also mediates various cytoprotective effects by binding and activating protein C. So far, the role of EPCR has not been studied in systemic sclerosis (SSc).
Objectives: To investigate the potential contribution of EPCR to the development of SSc. Read More