Search our Database of Scientific Publications and Authors

I’m looking for a

    3610 results match your criteria Alopecia Areata

    1 OF 73

    Dermatoglyphics in Ichthyosis and Alopecia Areata.
    Indian J Dermatol Venereol Leprol 1981 Jan-Feb;47(1):35-37
    A total of 80 cases comprising of 40 controls and twenty each of ichthyosis and alopecia areata were studied for dermatoglyphic patterns and ridge count. Statistically significant increased incidence of whorl pattern was observed in female cases of autosomal dominant and sex linked ichthyosis. Significant change in the distribution of patterns was found in female cases of alopecia areata. Read More

    Quality of life assessment in patients with alopecia areata and androgenetic alopecia in the People's Republic of China.
    Patient Prefer Adherence 2017 27;11:151-155. Epub 2017 Jan 27.
    Department of Oncology, Jinan Central Hospital Affiliated to Shandong University, Jinan, People's Republic of China.
    Introduction: In medical terms, alopecia is considered a relatively mild dermatological condition that nevertheless is a serious condition, but it causes major depression in many sufferers. Alopecia areata (AA) and androgenetic alopecia (AGA) are the main types of hair loss. This study assessed the quality of life (QoL) of Chinese patients with AA and AGA using the Dermatology Life Quality Index (DLQI) questionnaire. Read More

    Acquired Hair Curling after Diphenylcyclopropenone Immunotherapy in Alopecia Areata Patient.
    J Eur Acad Dermatol Venereol 2017 Feb 13. Epub 2017 Feb 13.
    Department of Dermatology and Institute of Hair and Cosmetic Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
    Contact immunotherapy using diphenylcyclopropenone (DPCP) is commonly used treatment modality for moderate to severe alopecia areata (AA)(1) . The most common side effects associated with topical immunotherapy using DPCP include eczema, hyperpigmentation, hypopigmentation, vitiligo, and cicatricial alopecia. However, we identified an interesting case of a patient whose entire scalp of straight hair (Figure 1A) became curly after DPCP immunotherapy, which has not been reported previously. Read More

    Janus kinase inhibitors in dermatology: A systematic review.
    J Am Acad Dermatol 2017 Feb 3. Epub 2017 Feb 3.
    Department of Dermatology, Hadassah - Hebrew University Medical Center, Jerusalem, Israel. Electronic address:
    Background: Janus kinase (JAK) inhibitors are emerging as a promising new treatment modality for many inflammatory conditions.

    Objective: Our aim was to systematically review the available data on the use of JAK inhibitors in cutaneous diseases.

    Methods: This is a systematic review of PubMed and ClinicalTrials. Read More

    Erythroid Differentiation Regulator 1 as a Novel Biomarker for Hair Loss Disorders.
    Int J Mol Sci 2017 Feb 3;18(2). Epub 2017 Feb 3.
    Department of Dermatology, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 07345, Korea.
    Erythroid differentiation regulator 1 (Erdr1) is known to be involved in the inflammatory process via regulating the immune system in many cutaneous disorders, such as psoriasis and rosacea. However, the role of Erdr1 in various hair loss disorders remains unclear. The aim of this study was to investigate the putative role of Erdr1 in alopecias. Read More

    Changes of serum trace elements level in patients with alopecia areata: A meta-analysis.
    J Dermatol 2017 Feb 2. Epub 2017 Feb 2.
    Department of Dermatology and Venerology, No. 2 Hospital of Jilin University, Changchun, China.
    Abnormalities of serum trace elements are involved in the etiology and pathogenesis of alopecia areata (AA); however, the results of published studies are controversial. The purpose of the present study is to investigate the alterations of serum level of trace elements and AA using a meta-analysis approach. We searched all articles indexed in PubMed, Embase and Science Citation Index published up to 30 April 2016 concerning the association between serum level of zinc, copper, iron/ferritin, selenium or magnesium and AA. Read More

    Sequential high- and low-dose systemic corticosteroid therapy for severe childhood alopecia areata.
    J Dtsch Dermatol Ges 2017 Jan;15(1):42-47
    Division of Immunology, Allergy and Infectious Diseases (DIAID), Department of Dermatology, Medical University of Vienna, Vienna, Austria.
    Background: Given the limited number of therapeutic options, severe childhood alopecia areata (AA) poses a clinical challenge. The best and most rapid response rates can be achieved with high-dose systemic corticosteroids, however, relapse following treatment discontinuation is inevitable. Due to systemic side effects, long-term high-dose corticosteroid regimens are not feasible. Read More

    Kombinierte Hoch-/Niedrig-Dosis-Therapie mit systemischen Glukokor-tikoiden bei schweren Verlaufsformen der Alopecia areata im Kindesalter.
    J Dtsch Dermatol Ges 2017 Jan;15(1):42-48
    Abteilung für Immundermatologie und infektiöse Hautkrankheiten (DIAID), Universitätsklinik für Dermatologie, Medizinische Universität Wien.
    Hintergrund: Schwere Verlaufsformen der Alopecia areata (AA) im Kindesalter sind aufgrund limitierter Optionen therapeutisch herausfordernd. Systemische, hochdosierte Glukokortikoide weisen die schnellste Ansprechrate auf, nach dem Absetzen kommt es allerdings zu Rezidiven. Eine längerfristige Hochdosis-Anwendung ist aufgrund der zu erwartenden Nebenwirkungen nicht empfehlenswert. Read More

    JAK inhibitors in dermatology: The promise of a new drug class.
    J Am Acad Dermatol 2017 Jan 28. Epub 2017 Jan 28.
    Department of Dermatology, Yale School of Medicine, New Haven, Connecticut. Electronic address:
    New molecularly targeted therapeutics are changing dermatologic therapy. Janus kinase-signal transducer and activator of transcription (JAK-STAT) is an intracellular signaling pathway upon which many different proinflammatory signaling pathways converge. Numerous inflammatory dermatoses are driven by soluble inflammatory mediators, which rely on JAK-STAT signaling, and inhibition of this pathway using JAK inhibitors might be a useful therapeutic strategy for these diseases. Read More

    Efficacy and safety of topical calcipotriol in management of alopecia areata: A pilot study.
    Dermatol Ther 2017 Jan 30. Epub 2017 Jan 30.
    Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India.
    Reports have highlighted serum vitamin D deficiency and reduced 1,25-dihydroxyvitamin D(3) receptors(VDR) expression on hair follicles of alopecia areata(AA) patients. Very few studies have demonstrated efficacy of topical calcipotriol (vitamin D analogue) in AA. We intended to study the efficacy of calcipotriol lotion 0. Read More

    Incident alopecia areata and vitiligo in adult women with atopic dermatitis: Nurses' Health Study 2.
    Allergy 2017 Jan 19. Epub 2017 Jan 19.
    Department of Dermatology, Warren Alpert Medical School, Providence, RI, USA.
    We aimed to determine the risk of alopecia areata (AA) and vitiligo associated with atopic dermatitis (AD) in a large cohort of US women, the Nurses' Health Study 2. We used logistic regression to calculate age- and multivariate-adjusted odds ratios to determine the risk of incident AA and vitiligo associated with AD diagnosed in or before 2009. A total of 87 406 and 87 447 participants were included in the AA and vitiligo analyses, respectively. Read More

    Remarkable Improvement of Nail Changes in Alopecia Areata Universalis with 10 Months of Treatment with Tofacitinib: A Case Report.
    Case Rep Dermatol 2016 Sep-Dec;8(3):262-266. Epub 2016 Oct 4.
    Unicesumar, Maringá, Brazil.
    Alopecia areata (AA) is a chronic, autoimmune disease. The main symptom is massive hair loss, localized or diffuse, in the scalp and the whole body. However, nails may also be involved, and brittleness, fragility and pitting can be signs of nail dystrophy in AA patients. Read More

    Late-onset alopecia areata: descriptive analysis of 30 cases.
    An Bras Dermatol 2016 Nov-Dec;91(6):844-845
    Irmandade da Santa Casa de Misericórdia de São Paulo - São Paulo (SP), Brazil.
    Alopecia areata is an autoimmune disease characterized by non-scaring hair loss. The onset in over 50-year-old patients is rare and has barely been studied. Cases of this disease have been retrospectively analyzed - according to clinical forms, extension, and associated diseases - to assess alopecia areata characteristics in a group of patients whose disease onset was after the age of 50. Read More

    Seasonal leukotrichia in a German shepherd dog. A case report.
    Tierarztl Prax Ausg K Kleintiere Heimtiere 2017 Feb 17;45(1):46-51. Epub 2017 Jan 17.
    Janine Classen, Medizinische Kleintierklinik, Zentrum für klinische Kleintiermedizin, Ludwig-Maximilians-Universität München, Veterinärstraße 13, 80539 München, E-Mail:
    Leukotrichia can be caused by a variety of metabolic and inflammatory diseases. Canine alopecia areata is a rare multifactorial benign non-scarring alopecia. This case report describes a seasonally recurrent leukotrichia associated with alopecia areata in a German shepherd dog. Read More

    Tofacitinib, an Oral Janus Kinase Inhibitor: Perspectives in Dermatology.
    Curr Med Chem 2017 Jan 12. Epub 2017 Jan 12.
    Department of Dermatovenereology, University Hospital Center Zagreb, School of Medicine, University of Zagreb, Salata 4, 10000 Zagreb, Croatia.
    Background: Tofacitinib (formerly known as CP-690,550, CP690550, tasocitinib), a novel selective immunosuppressant, is a small molecule classified as Janus kinase inhibitor. The aim of this review article is to present updated data summary on the tofacitinib in the field of dermatology.

    Method: We undertook a structured search of bibliographic databases for peer-reviewed scientific articles, including review articles, original research articles as well as case report articles based on inclusion/exclusion criteria. Read More

    Efficacy of superficial cryotherapy on the eyebrows of patients with alopecia universalis also treated with contact immunotherapy on the scalp: a prospective, split-face comparative study.
    Int J Dermatol 2017 Feb;56(2):184-189
    Department of Dermatology and Institute of Hair and Cosmetic Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
    Background: Few treatment modalities are available for treating alopecia areata (AA) of the eyebrow. Due to the anatomical proximity of the eyebrows to the eyes, safety issues and side effects should always be taken into consideration when choosing the treatment modality. This study was designed to examine the efficacy of superficial cryotherapy on patients with AA of the eyebrow. Read More

    Trichoscopic clues for diagnosis of alopecia areata and trichotillomania in Asians.
    Int J Dermatol 2017 Feb;56(2):161-165
    Division of Dermatology, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
    Background: Trichoscopy has become a useful diagnostic tool for various hair and scalp diseases, including alopecia areata (AA) and trichotillomania (TTM), which are sometimes difficult to distinguish clinically.

    Objectives: To describe trichoscopic findings of AA and TTM in an Asian population and to establish diagnostic clues for these conditions.

    Methods: Trichoscopy was performed with a handheld dermoscope in 52 patients diagnosed with AA and 23 patients diagnosed with TTM. Read More

    New Treatments for Hair Loss.
    Actas Dermosifiliogr 2017 Jan 3. Epub 2017 Jan 3.
    Hospital Virgen Macarena, Sevilla, España.
    The treatment of hair loss is an important part of clinical dermatology given the prevalence of the problem and great impact on patients' quality of life. Many new treatments have been introduced in recent years. This review summarizes the main ones in 4 groups: a) For androgenetic alopecia, we discuss new excipients for oral minoxidil, dutasteride, and finasteride as well as new forms of topical application; prostaglandin agonists and antagonists; low-level laser therapy; and regenerative medicine with Wnt signaling activators and stem cell therapy. Read More

    Diversity in Dermatology Clinical Trials: A Systematic Review.
    JAMA Dermatol 2017 Jan 4. Epub 2017 Jan 4.
    Department of Dermatology, Brigham & Women's Hospital, Harvard Medical School, Boston, Massachusetts.
    Importance: Though there have been significant shifts in US demographic data over the past 50 years, research cohorts lack full racial and ethnic representation. There is little data available regarding the diversity of dermatology research cohorts with respect to sex, race, and ethnicity.

    Objective: To characterize and assess the representation of racial and ethnic minorities and women in randomized controlled trials across a range of dermatologic conditions. Read More

    Bilateral Half-Head Comparison of 1% Anthralin Ointment in Children with Alopecia Areata.
    Pediatr Dermatol 2017 Jan 3. Epub 2017 Jan 3.
    Department of Dermatology, School of Medicine, Istanbul Medipol University, Istanbul, Turkey.
    Background/objectives: Alopecia areata (AA) is one of the most difficult skin diseases to manage well. In children, anthralin is commonly used for the treatment of AA. Available research consists of a limited number of uncontrolled trials that assessed the effectiveness of anthralin in promoting hair growth in patients with AA. Read More

    Alopecia areata incognita in Cronkhite-Canada Syndrome.
    Br J Dermatol 2016 Dec 28. Epub 2016 Dec 28.
    Department of Dermatopathology, St John's Institute of Dermatology, St Thomas' Hospital, London, UK.
    Cronkhite-Canada syndrome is an acquired inflammatory polyposis syndrome in which alopecia, onychomadesis and hyperpigmentation occur concurrently with gastrointestinal symptoms. The pathophysiology of alopecia in Cronkhite-Canada Syndrome has not been definitively elucidated and we present evidence for alopecia incognita as a possible mechanism of hair loss. This article is protected by copyright. Read More

    Janus kinase (JAK) inhibitors for the treatment of skin and hair disorders: a review of literature.
    J Dermatolog Treat 2017 Jan 22:1-11. Epub 2017 Jan 22.
    a Center for Research & Training in Skin Diseases & Leprosy , Tehran University of Medical Sciences , Tehran , Iran.
    Janus kinase family (JAKs) has recently attracted the attention of many researchers, and several JAK inhibitor drugs have been developed targeting different members of the JAK family. Tofacitinib and ruxolitinib are US FDA approved drugs in this family for rheumatoid arthritis and myeloproliferative diseases, respectively. Dysregulation of JAK/STAT pathway is also involved in many skin diseases, specifically inflammatory disorders. Read More

    Hair pull test: Evidence-based update and revision of guidelines.
    J Am Acad Dermatol 2017 Mar 20;76(3):472-477. Epub 2016 Dec 20.
    Division of Dermatology, Ottawa Hospital, Ottawa, Ontario, Canada. Electronic address:
    Background: The hair pull test lacks validation and has unclear pretest guidelines.

    Objective: We sought to quantify normal hair pull test values and elucidate the effect of pretest hair washing and brushing. The impact of hair texture and lifestyle was also examined. Read More

    Alopecia areata as a paraneoplastic syndrome of gastric cancer.
    Rev Esp Enferm Dig 2017 Jan;109(1):83-84
    Medicina Interna, Hospital Povisa.
    Alopecia areata produces hair loss in circular patches by an immune mechanism. The association with hematologic malignancies and with digestive tumors has been described. We report the case of a man who presented alopecia areata and two months later he was diagnosed with gastric adenocarcinoma. Read More

    Nutrition and skin: Kids are not just little people.
    Clin Dermatol 2016 Nov - Dec;34(6):698-709. Epub 2016 Jul 9.
    Department of Pediatrics, Seattle Children's Hospital, University of Washington School of Medicine, Seattle, WA.
    There has been a surge of new data regarding the pathophysiology of skin diseases. We are appreciating the sophisticated interplay among the skin, the immune system, and the environment. More elegant and highly specific medicines have been designed to target certain immune mediators of the adaptive immune system. Read More

    Immune-related alopecia (areata and universalis-type) in cancer patients receiving immune checkpoint inhibitors.
    Br J Dermatol 2016 Dec 11. Epub 2016 Dec 11.
    Dermatology Service, Institut Universitaire du Cancer.
    CTLA-4, PD-1, and PD-L1 monoclonal antibodies, commonly known as immune checkpoint inhibitors, are used for the treatment of various malignancies. The mechanism of action involves the inhibition of negative regulators of immune activation, which results in many patients developing immune-related adverse events (irAEs) including endocrinopathies, pneumonitis, colitis, hepatitis and dermatologic events. Dermatologic irAEs include maculopapular rash, pruritus, vitiligo, blistering disorders, mucocutaneous lichenoid eruptions, rosacea, and exacerbation of psoriasis. Read More

    Evaluation of Clinical Significance of Dermoscopy in Alopecia Areata.
    Indian J Dermatol 2016 Nov-Dec;61(6):628-633
    Department of Dermatology, Venereology, Leprology, Katuri Medical College and Hospital, Guntur, Andhra Pradesh, India.
    Background: Alopecia areata (AA) is a common, chronic inflammatory disease characterized by nonscarring hair loss on the scalp or any hair-bearing area of the body. Recently, dermoscopy, a noninvasive diagnostic procedure, has been employed for the diagnosis of AA.

    Aim: To evaluate various dermoscopic patterns in AA and correlate these patterns with the disease activity and severity. Read More

    Hair diseases: a big problem on a small surface.
    Postepy Dermatol Alergol 2016 Oct 21;33(5):317-322. Epub 2016 Oct 21.
    Department of Skin Structural Studies, Chair of Cosmetology, School of Pharmacy with Division of Medicine in Sosnowiec, Medical University of Silesia, Katowice, Poland.
    Civilizational progress initially contributes to the problem of hair loss and then to alopecia as regards both frequency and therapeutic dilemmas. The work presents trichological problems which occur more rarely, i.e. Read More

    Alopecia Areata-Part III: Prognosis and Treatment.
    Skinmed 2016 1;14(5):361-365. Epub 2016 Oct 1.
    Sector of Dermatology and Post-Graduation Course, University Hospital and School of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil;
    The prognosis of alopecia areata is better in cases with single and small lesions, and the variability of the extension of the disease is one of the criteria for the choice of treatment modality. Several medications have been described in the literature for the treatment of alopecia areata, including corticosteroids, minoxidil, and diphencyprone. The authors review treatments for alopecia areata. Read More

    Study of the comparative expression of CXCL9, CXCL10 and IFNγ in vitiligo and alopecia areata patients.
    Pigment Cell Melanoma Res 2016 Nov 12. Epub 2016 Nov 12.
    C3M, INSERM U1065, team 12, Nice, France.
    Vitiligo and Alopecia areata (AA) are autoimmune T cell-mediated diseases of the skin that share the implication of the IFNγ pathway in their pathophysiology. C-X-C motif chemokine receptor 3 (CXCR3) and its ligands, C-X-C motif chemokine ligand 9 (CXCL9), CXCL10 and CXCL11, are linked to the Th1 pattern and have been suggested as one of the most relevant chemokine axes that promote T cell migration in different autoimmune and inflammatory processes (Lacotte et al., 2009). Read More

    Dermal Titanium Dioxide Deposition Associated With Intralesional Triamcinolone Injection.
    Am J Dermatopathol 2016 Dec;38(12):e163-e166
    *Department of Dermatology, University of Southern California, Keck School of Medicine, Los Angeles, CA; †Center for Dermatology Care, Thousand Oaks, CA; ‡Department of Pathology, SUNY Upstate Medical University, Syracuse, NY; and §Central Coast Pathology, San Luis Obispo, CA.
    Cutaneous discoloration secondary to dermal deposition of titanium dioxide (TiO2) particles is recognized but seldom reported in the literature. In this report, the authors describe the case of a 61-year-old gentleman, with a long history of alopecia areata, who presented with numerous, discrete dark blue macules on the scalp. Scanning electron microscopy with energy dispersive x-ray spectroscopy analysis ultimately identified the macules as deposits of TiO2. Read More

    Polyglandular autoimmune syndrome type III with a prevalence of cutaneous features.
    Clin Exp Dermatol 2017 Jan 13;42(1):61-63. Epub 2016 Nov 13.
    Department of Medicine and Aging Science, Dermatologic Clinic, University G. d'Annunzio, Chieti, Italy.
    Polyglandular autoimmune syndrome (PAS) is the name given to a group of autoimmune disorders of the endocrine glands. PAS type III (PAS III) comprises several autoimmune diseases (autoimmune thyroiditis, immune-mediated diabetes mellitus, pernicious anaemia, vitiligo, alopecia areata and many others) and is subdivided into four subcategories. We report the case of a 52-year-old woman with autoimmune thyroiditis, vitiligo, alopecia areata, psoriasis and lichen sclerosus, suggesting a clinical diagnosis of PAS IIIC with a singular prevalence of cutaneous features. Read More

    A case of alopecia as IgG4-related skin disease.
    Mod Rheumatol 2016 Nov 23:1-4. Epub 2016 Nov 23.
    a Department of Dermatology , Wakayama Medical University, Graduate School of Medicine , Wakayama , Japan.
    A 53-year-old man with autoimmune pancreatitis as IgG4-related disease presented alopecia. Immunostaining showed perifollicular infiltration of IgG4-positive cells and perifollicular/intrafollicular infiltration of predominantly CD4-positive cells, especially in the upper and lower parts. Alopecia areata is characterized by perifollicular/intrafollicular lymphocyte infiltration of the lower bulb and inflammation in the upper dermis. Read More

    Alopecia Areata as a Manifestation of Systemic Lymphoma: Report of Two Cases.
    Skin Appendage Disord 2016 Sep 4;2(1-2):63-66. Epub 2016 Aug 4.
    Department of Dermatology, Hadassah - Hebrew University Medical Center, Jerusalem, Israel.
    Alopecia areata is a common autoimmune disorder leading to hair loss. It usually affects individuals under the age of 40, and first appearance in older subjects is considered uncommon. Here, we report 2 cases of rapidly progressing alopecia areata, which appeared for the first time in adults. Read More

    Trichoscopy of Focal Alopecia in Children - New Trichoscopic Findings: Hair Bulbs Arranged Radially along Hair-Bearing Margins in Aplasia Cutis Congenita.
    Skin Appendage Disord 2016 Sep 30;2(1-2):1-6. Epub 2016 Apr 30.
    Department of Dermatology, Medical University of Warsaw, Warsaw, Poland.
    Purpose: To establish whether trichoscopy can be useful in the differential diagnosis of patchy alopecia in children.

    Procedures: The study was a retrospective analysis (2012-2015) and included 68 patients under 6 years of age. The inclusion criteria were age and the presence of 1-3 alopecia patches. Read More

    The Most Frequent Herbs Proposed by Iranian Traditional Medicine for Alopecia Areata.
    Iran J Med Sci 2016 May;41(3 Suppl):S69
    Traditional Medicine and Materia Medica Research Center, Department of Traditional Pharmacy, School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
    Background: Alopecia areata (AA) is a common immune-mediated hair loss disorder. AA has a reported incidence of 0.1-0. Read More

    The Frequency Distribution of Celiac Autoantibodies in Alopecia Areata.
    Int J Prev Med 2016 14;7:109. Epub 2016 Sep 14.
    Department of Dermatology, Skin Diseases and Leishmaniasis Research Center, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
    Background: Alopecia areata (AA) is a noncicatricial (nonscarring) alopecia. The association between AA and celiac disease (CD) is debatable. Several studies declare the relationship between AA and CD as measurement of celiac autoantibodies (anti-gliadin IgA and anti-gliadin IgG), but a few studies consider anti-tissue transglutaminase IgA. Read More

    Traditional Chinese Medicine Use among Patients with Psoriasis in Taiwan: A Nationwide Population-Based Study.
    Evid Based Complement Alternat Med 2016 16;2016:3164105. Epub 2016 Oct 16.
    Graduate Institute of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan; Department of Chinese Medicine, China Medical University Hospital, Taichung, Taiwan; School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan; Research Center for Chinese Medicine & Acupuncture, China Medical University, Taichung, Taiwan; Research Center for Traditional Chinese Medicine, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.
    Traditional Chinese medicine (TCM) has long been used for patients with psoriasis. This study aimed to investigate TCM usage in patients with psoriasis. We analyzed a cohort of one million individuals representing the 23 million enrollees randomly selected from the National Health Insurance Research Database in Taiwan. Read More

    Tofacitinib for the treatment of severe alopecia areata and variants: A study of 90 patients.
    J Am Acad Dermatol 2017 Jan 2;76(1):22-28. Epub 2016 Nov 2.
    Department of Dermatology, Yale University, New Haven, Connecticut. Electronic address:
    Background: Alopecia areata (AA) is a common autoimmune disorder. There are no reliably effective therapies for AA.

    Objective: We sought to evaluate the safety and efficacy of the Janus kinase 1/3 inhibitor, tofacitinib, in a series of patients over an extended period of time. Read More

    Tofacitinib for the treatment of alopecia areata and variants in adolescents.
    J Am Acad Dermatol 2017 Jan 2;76(1):29-32. Epub 2016 Nov 2.
    Department of Dermatology, Yale University, New Haven, Connecticut.
    Background: There are no reliably effective therapies for alopecia areata (AA).

    Objective: We sought to evaluate the benefit and adverse effects of the Janus kinase 1/3 inhibitor, tofacitinib, in a series of adolescent patients with AA.

    Methods: We reviewed the records of 13 adolescent patients with AA treated with tofacitinib. Read More

    Common phenotype and different non-HLA genes in Graves' disease and alopecia areata.
    Hum Immunol 2017 Feb 31;78(2):185-189. Epub 2016 Oct 31.
    Department of Endocrinology, Metabolism and Diabetes, Kindai University Faculty of Medicine, 377-2 Ohno-higashi, Osaka-sayama, Osaka 589-8511, Japan. Electronic address:
    Our previous observations clarified that Graves' disease (GD) is the most frequent autoimmune disease in patients with alopecia areata (AA), and 42.7% of patients with AA were positive for thyrotropin receptor antibody (TRAb). A class II HLA haplotype DRB1(∗)15:01-DQB1(∗)06:02 was suggested to contribute to autoimmunity against the thyroid gland in AA. Read More

    1 OF 73