20,693 results match your criteria Alopecia Areata


The Role of Vitamins and Minerals in Hair Loss: A Review.

Dermatol Ther (Heidelb) 2018 Dec 13. Epub 2018 Dec 13.

Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, 1475 NW 12th Ave. Suite 2175, Miami, FL, 33136, USA.

People commonly inquire about vitamin and mineral supplementation and diet as a means to prevent or manage dermatological diseases and, in particular, hair loss. Answering these queries is frequently challenging, given the enormous and conflicting evidence that exists on this subject. There are several reasons to suspect a role for micronutrients in non-scarring alopecia. Read More

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December 2018

Tissue engineering of human hair follicles using a biomimetic developmental approach.

Nat Commun 2018 Dec 13;9(1):5301. Epub 2018 Dec 13.

Department of Dermatology, Columbia University Medical Center, New York, NY, 10032, USA.

Human skin constructs (HSCs) have the potential to provide an effective therapy for patients with significant skin injuries and to enable human-relevant drug screening for skin diseases; however, the incorporation of engineered skin appendages, such as hair follicles (HFs), into HSCs remains a major challenge. Here, we demonstrate a biomimetic approach for generation of human HFs within HSCs by recapitulating the physiological 3D organization of cells in the HF microenvironment using 3D-printed molds. Overexpression of Lef-1 in dermal papilla cells (DPC) restores the intact DPC transcriptional signature and significantly enhances the efficiency of HF differentiation in HSCs. Read More

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December 2018

Evaluation of Serum Paraoxonase, Arylesterase, Prolidase Activities and Oxidative Stress in Patients with Alopecia Areata.

Skin Pharmacol Physiol 2018 Dec 13;32(2):59-64. Epub 2018 Dec 13.

Private practice, Kutahya, Turkey.

Background: Alopecia areata (AA) is a disease characterized by the hair loss sharply limited in any part of the body, especially on the scalp, in circular or oval areas. The purpose of this study is to search the serum paraoxonase 1 (PON1), arylesterase and oxidative status with serum prolidase activities in people with AA.

Methods: The study included 60 AA and 50 healthy control subjects. Read More

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December 2018

Lithium Treatment Is Safe in Children With Intellectual Disability.

Front Mol Neurosci 2018 22;11:425. Epub 2018 Nov 22.

Henan Key Laboratory of Child Brain Injury, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Lithium is a widely used and effective treatment for individuals with psycho-neurological disorders, and it exhibits protective and regenerative properties in multiple brain injury animal models, but the clinical experience in young children is limited due to potential toxicity. As an interim analysis, this paper reports the safety/tolerability profiles of low-dose lithium treatment in children with intellectual disability (ID) and its possible beneficial effects. In a randomized, single-center clinical trial, 124 children with ID were given either oral lithium carbonate 6 mg/kg twice per day or the same dose of calcium carbonate as a placebo ( = 62/group) for 3 months. Read More

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November 2018

Establishment of infestivity model for var in Nigerian dogs.

J Parasit Dis 2018 Dec 22;42(4):519-526. Epub 2018 Aug 22.

2Department of Veterinary Pathology, University of Ibadan, Ibadan, Nigeria.

Experimental transmission patterns involved with the establishment of mange in dogs were studied to ascertain the effective means of infestation model for mange experiments in dogs. A total of eighteen (18) dogs were used out of which three (3) were naturally infested with var Five (5) healthy dogs were co-mingled with the three (3) donor dogs for direct contact transmission. Another five (5) mange free dogs were aggregated in a kennel recently vacated by mange infested dogs for environmental and formite transmission while the last five (5) healthy dogs had scrapings from a proximate area of mange lesion sites transferred into the pinnae of each dog for experimental and indirect contact transmission. Read More

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December 2018

Efficacy of topical dithranol (Dithrocream ) in the treatment of alopecia areata: a retrospective case series.

Authors:
A Daunton M Harries

Br J Dermatol 2018 Dec 10. Epub 2018 Dec 10.

The Dermatology Centre, Salford Royal NHS Foundation Trust, Salford, U.K.

Topical dithranol is an alternative therapy to topical diphencyprone for extensive AA, with the advantage that it can be applied at home. It is also safe in children and has low risk for use during pregnancy. Its precise mechanism of action is unknown, but it is plausible that the local cytokine profile induced by its irritant effect "compete" with the inflammatory milieu incited during the inflammatory cell attack on hair follicles. Read More

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December 2018
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Dermatitis and alopecia in a patient treated with dupilumab: a new adverse effect?

Clin Exp Dermatol 2018 Dec 9. Epub 2018 Dec 9.

Department of Dermatology, Puerta de Hierro Hospital, C/Manuel de Falla, 1, 28222, Majadahonda, Madrid, Spain.

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December 2018

Evaluation of long-term efficacy of finasteride in Korean men with androgenetic alopecia using the basic and specific classification system.

J Dermatol 2018 Dec 7. Epub 2018 Dec 7.

Department of Dermatology, Seoul National University Bundang Hospital, Seongnam, Korea.

Finasteride 1 mg is considered to be the standard treatment method for male androgenetic alopecia (AGA). However, there have only been a few studies investigating its long-term efficacy. Moreover, its effect on various types of AGA remains unknown. Read More

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December 2018

Tolerability of long-term fluconazole therapy.

J Antimicrob Chemother 2018 Dec 6. Epub 2018 Dec 6.

Department of Medical Microbiology and Immunology, University of California, Med Science Dr., Davis, CA, USA.

Background: Fluconazole is a commonly prescribed first-generation triazole antifungal. Although the toxicity profile of fluconazole has been evaluated in clinical trials, there are scant data regarding its tolerability with long-term therapy. Treatment guidelines for coccidioidomycosis recommend fluconazole therapy and severe or disseminated infections can require lifelong treatment. Read More

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December 2018

Complications in Brow Lifts: A Systemic Review of Surgical and Nonsurgical Brow Rejuvenations.

Plast Reconstr Surg Glob Open 2018 Oct 15;6(10):e1943. Epub 2018 Oct 15.

Dallas Plastic Surgery Institute, Dallas, Tex.

Background: Brow lift has been a part of plastic surgeons' armamentarium for over a century. Although there are multiple different techniques available, there has been a dearth of literature comparing which technique is better and has lesser complications. In this study, we performed a systemic literature review of all brow lift techniques to determine and compare complication rates of each technique. Read More

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October 2018

Alopecia Areata in Severe Atopic Dermatitis Treated With Dupilumab.

J Investig Allergol Clin Immunol 2018 Dec;28(6):420-421

Allergy Department, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain.

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December 2018

The influence of interferon on healthy and diseased skin.

Cytokine 2018 Dec 6. Epub 2018 Dec 6.

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address:

Type I interferons (IFNs) are an immunomodulatory class of cytokines that serve to protect against viral and bacterial infection. In addition, mounting evidence suggests IFNs, particularly type I but also IFNγ, are important to the pathogenesis of autoimmune and inflammatory skin diseases, such as cutaneous lupus erythematosus (CLE). Understanding the role of IFNs is relevant to anti-viral responses in the skin, skin biology, and therapeutics for these IFN-related conditions. Read More

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December 2018
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The relation between androgenetic thin hair diagnosed by trichoscope and benign prostatic hyperplasia.

J Cosmet Dermatol 2018 Dec 5. Epub 2018 Dec 5.

Faculty of Medicine, Benha University, Benha, Egypt.

Background: Androgenetic alopecia carries a major cosmetic disfigurement and benign prostatic hyperplasia is associated with many urinary tract symptoms and both diseases are mediated by dihydrotestosterone.

Objectives: The study aimed to determine the relationship between hair diameter in androgenetic alopecia diagnosed, by trichoscope, to benign prostatic hyperplasia symptoms and signs.

Methods: Fifty androgenetic alopecia males and 50 normal males as control were included. Read More

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December 2018
1 Read

Rebound effect associated with JAK inhibitor use in the treatment of alopecia areata.

J Eur Acad Dermatol Venereol 2018 Dec 6. Epub 2018 Dec 6.

Department of Dermatology, Tufts Medical Center, Boston, MA.

Alopecia areata (AA) is a common autoimmune disease driven by Th1 cytokines characterized by non-scarring hair loss. Mouse models have demonstrated that IFN-γ-producing NKG2D+ CD8+ cytotoxic T lymphocytes (CTLs) are essential for disease pathogenesis, along with JAK-STAT dependent cytokines IFN-γ and IL-15, which induce autoreactive T cell activation. This article is protected by copyright. Read More

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December 2018
2 Reads

Patient Preferences Regarding Chemotherapy in Metastatic Breast Cancer-A Conjoint Analysis for Common Taxanes.

Front Oncol 2018 21;8:535. Epub 2018 Nov 21.

Department of Obstetrics and Gynaecology, University Medical Centre Mannheim, Heidelberg University, Mannheim, Germany.

The purpose of this investigation was to explore patient perception regarding the importance of efficacy, toxicity, and logistics in the choice of regimen of taxane-based chemotherapy (CHT) for patients with metastatic breast cancer (MBC). This dual-center study analyzed data of 100 women diagnosed with MBC, who were asked for their preferences regarding chemotherapy by means of conjoint analysis. Included attributes were progression free survival (PFS), application form, time and frequency, need of premedication, risk of alopecia, fatigue, febrile neutropenia, and neuropathy. Read More

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November 2018

Unusual Maculopapular Rash on the Scalp of a Patient with Mediterranean Spotted Fever.

Med Princ Pract 2018 Dec 3. Epub 2018 Dec 3.

Objective: To report a rare case of maculopapular rash on the scalp in a patient with Mediterranean spotted fever (MSF).

Clinical Presentation And Intervention: A 58-year-old woman with breast cancer and chemotherapy-induced alopecia contracted MSF. Her clinical features were typical, except for a maculopapular rash covering the scalp. Read More

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December 2018
1 Read

Protective Role of α2-Macroglobulin against Jaw Osteoradionecrosis in a Preclinical Rat Model.

J Oral Pathol Med 2018 Dec 1. Epub 2018 Dec 1.

Department of Oral and Maxillofacial Surgery, The Sixth Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510655, China.

Objective: We have previously demonstrated the effect of alpha-2-macroglobulin (α2M) in the remediation of radiation-induced cellular damage. Here, we investigated the protective effects of α2M in a preclinical rat model of jaw osteoradionecrosis (ORN).

Methods: Eighteen rats were divided randomly into three groups: the control group, the radiation therapy (RT) alone group, and the radiated mandibles pretreated with α2M (α2M + RT) group. Read More

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December 2018
2 Reads
1.870 Impact Factor

Alopecia Areata and Poliosis: A Retrospective Analysis of 258 Cases.

J Am Acad Dermatol 2018 Nov 28. Epub 2018 Nov 28.

Department of Dermatology and Institute of Hair and Cosmetic Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea. Electronic address:

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November 2018

Response to tofacitinib therapy of eyebrows and eyelashes in alopecia areata.

J Am Acad Dermatol 2018 Nov 28. Epub 2018 Nov 28.

Department of Dermatology, Yale University School of Medicine, New Haven, CT. Electronic address:

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November 2018

The risk of dermatological toxicities of combined BRAF and MEK inhibition versus BRAF inhibition alone in melanoma patients: a systematic review and meta-analysis.

Cutan Ocul Toxicol 2018 Dec 2:1-17. Epub 2018 Dec 2.

a Department of Pharmacy , Renmin Hospital of Wuhan University , Wuhan , Hubei , 430060 , P.R. China.

Background: This meta-analysis was conducted to assess the risk of dermatological toxicities of combined BRAF and MEK inhibition versus BRAF inhibition alone in melanoma patients.

Methods: We considered relevant prospective randomized Phase I, II and III trials of melanoma patients on the combined BRAF and MEK inhibition versus BRAF inhibition, describing events of rash, photosensitivity reaction (PR), hyperkeratosis (HK), alopecia, cutaneous squamous-cell carcinom(cSCC), skin papilloma(SP), pruritus and hand-foot syndrome(HFS), as eligible for inclusion.

Results: Eight trials comprising 3163 patients were included in the meta-analysis. Read More

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December 2018

Treatment of canine sarcoptic mange with afoxolaner (NexGard) and afoxolaner plus milbemycin oxime (NexGard Spectra) chewable tablets: efficacy under field conditions in Portugal and Germany.

Parasite 2018 5;25:63. Epub 2018 Dec 5.

Boehringer Ingelheim Vetmedica GmbH, Kathrinenhof Research Center, 83101 Rohrdorf, Germany.

The efficacy of NexGard and NexGard Spectra against sarcoptic mange in dogs was evaluated in a clinical field study. Skin scrapings from dogs presenting signs suggestive of sarcoptic mange were examined to confirm infestation. A total of 106 dogs were screened at eight sites in Portugal and Germany. Read More

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December 2018
1 Read

Randomized controlled trial on a PRP-like cosmetic, biomimetic peptides based, for the treatment of Alopecia Areata.

J Dermatolog Treat 2018 Dec 4:1-26. Epub 2018 Dec 4.

a International Hair Research Foundation , Milan , Italy.

Background Alopecia areata (AA) is a non-scarring auto-immune hair disorder. Recent researches explained the role of growth factors (GFs) in hair follicle cycling. The main reservoir of GFs are alpha-granules of platelets and novel procedures have been implemented aimed at collecting platelet-rich plasma (PRP). Read More

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December 2018

Serum sickness disease in a patient with alopecia areata and Meniere' disease after PRP procedure.

Dermatol Ther 2018 Dec 4:e12798. Epub 2018 Dec 4.

Department of Dermatology, Sexually Transmitted Diseases and Clinical Immunology The University of Warmia and Mazury, Poland.

Background: Platelet Rich Plasma procedure (PRP) is considered to be one of the safest aesthetic procedures. Adverse reactions after PRP administration are extreme rare.

Purpose: We present the patient with serum sickness disease (SSD) after PRP procedure. Read More

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December 2018

Linear alopecia areata.

JAAD Case Rep 2018 Nov 14;4(10):1072-1073. Epub 2018 Nov 14.

Department of Dermatology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou City, China.

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November 2018

Living with alopecia areata: An online qualitative survey study.

Br J Dermatol 2018 Nov 30. Epub 2018 Nov 30.

Centre for Appearance Research, University of the West of England, Bristol.

Background: Living with alopecia areata, totalis and universalis (collectively referred to here as AA) involves unpredictable, sometimes rapid hair loss. There is currently no effective treatment and patients describe feelings of shock, loss, trauma and disrupted identity. Cultural meanings attached to hair and hair loss, including associations between hair and femininity, and hair loss and cancer may exacerbate distress. Read More

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November 2018
3 Reads

Acne development in male androgenetic alopecia.

Clin Exp Dermatol 2018 Nov 29. Epub 2018 Nov 29.

Division of Dermatology, University of California Los Angeles David Geffen School of Medicine, 200 Medical Plaza Suite 465, Los Angeles, CA, USA.

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November 2018

Diffuse nonscarring alopecia.

Cutis 2018 Oct;102(4):E4-E5

Private practice, Hickory, North Carolina, USA.

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October 2018

Frontal Fibrosing Alopecia and Discoid Lupus Erythematosus: More Than a Coincidence.

Actas Dermosifiliogr 2018 Oct 25. Epub 2018 Oct 25.

Unidad de Dermatología Médico-Quirúrgica y Venereología, Hospital Universitario Campus de la Salud de Granada, Granada, España. Electronic address:

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October 2018

Adipose tissue transplant in recurrent folliculitis decalvans.

Int J Immunopathol Pharmacol 2018 Mar-Dec;32:2058738418814688

Department of Plastic and Reconstructive Surgery, San Gallicano Dermatological Institute IRCCS, Rome, Italy.

Folliculitis decalvans is a rare clinical disorder classified as primary neutrophilic scarring alopecia with a slight preference for the male gender. Here, we report the use of autologous fat transplantation as a source of stem cell therapy for hair re-growth assisted by inflammatory action of the fat itself in a female patient. The patient underwent adipose transplantation in April and September 2017. Read More

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November 2018
10 Reads

A Case Report of Scrotal Rejuvenation: Laser Treatment of Angiokeratomas of the Scrotum.

Authors:
Philip R Cohen

Dermatol Ther (Heidelb) 2018 Nov 26. Epub 2018 Nov 26.

San Diego Family Dermatology, National City, CA, USA.

Scrotal rejuvenation encompasses not only the functional quality but also the aesthetic appearance of the scrotum. It includes medical therapy and procedural interventions to improve scrotal conditions that require morphologic restoration and/or aesthetic alteration. Rejuvenation of the scrotum may be appropriate for aging-related and non-aging-related changes concerning the hair (alopecia and hypertrichosis), the morphology (laxity and wrinkles), and/or the vascularity (angiokeratoma) of the scrotum. Read More

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November 2018
4 Reads

Scalp Sarcoidosis Presenting as Cicatricial Alopecia.

J Am Osteopath Assoc 2018 Dec;118(12):824-826

Sarcoidosis is a granulomatous condition that has a highly variable presentation. One rare presentation of sarcoidosis is cutaneous scalp sarcoidosis. Usually scalp sarcoid presents as a scarring alopecia, but it can be nonscarring. Read More

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December 2018
2 Reads

Treatment of female pattern hair loss with combination therapy.

Semin Cutan Med Surg 2018 Dec;37(4):247-253

Department of Dermatology, Cleveland Clinic Foundation, Cleveland, Ohio, USA.

Female pattern hair loss (FPHL) is a common nonscarring alopecia characterized by progressive loss of terminal hairs. FPHL is a major concern for women and has a high impact on quality of life. Therapeutic regimen is often challenging and requires multiple combinations of topical, systemic, and interventional therapies to control hair loss and produce satisfactory hair regrowth. Read More

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December 2018
1 Read

Gain-of-function variants in the ODC1 gene cause a syndromic neurodevelopmental disorder associated with macrocephaly, alopecia, dysmorphic features, and neuroimaging abnormalities.

Am J Med Genet A 2018 Nov 26. Epub 2018 Nov 26.

Division of Genetics and Genomics, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.

Polyamines serve a number of vital functions in humans, including regulation of cellular proliferation, intracellular signaling, and modulation of ion channels. Ornithine decarboxylase 1 (ODC1) is the rate-limiting enzyme in endogenous polyamine synthesis. In this report, we present four patients with a distinct neurometabolic disorder associated with de novo heterozygous, gain-of-function variants in the ODC1 gene. Read More

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November 2018
3 Reads

Frontal fibrosing alopecia: a case series of 65 patients seen in a single Italian centre.

J Eur Acad Dermatol Venereol 2018 Nov 25. Epub 2018 Nov 25.

Dermatology, Department of Specialized, Diagnostic and Experimental Medicine, University of Bologna, Bologna, Italy.

Background: Frontal fibrosing alopecia (FFA) is increasing in prevalence worldwide and several series from different countries have been published, in order to detect possible causes of the disease outbreak.

Objective: To analyze the epidemiological, clinical and trichoscopic features of FFA seen in an Italian Dermatology Unit.

Methods: Clinical, trichoscopy, histopathology and medical details of all patients were compared with literature and general population data. Read More

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November 2018
3 Reads

Incidence and risk factors for alopecia in survivors of critical illness: A multi-centre observational study.

J Crit Care 2018 Nov 16;50:31-35. Epub 2018 Nov 16.

Department of Anaesthetics, Glan Clwyd Hospital, Bodelwyddan, Denbighshire, UK.. Electronic address:

Purpose: To investigate the incidence, nature and risk factors for patient-reported alopecia in survivors of critical illness.

Materials And Methods: A multi-centre, mixed methods observational study in the intensive care units (ICU) of ten hospitals in Wales. All patients with an ICU stay of 5 days or more, able to give consent were included. Read More

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November 2018
1 Read

Adverse drug reactions of anticancer drugs derived from natural sources.

Food Chem Toxicol 2018 Nov 22;123:522-535. Epub 2018 Nov 22.

Value Addition Research and Development-Human Health, National Innovation Foundation-India, Autonomous Body of Department of Science and Technology, Govt. of India, Grambharti, Mahudi Road, Gandhinagar, 382650, Gujarat, India. Electronic address:

Cancer, a life threatening disease adversely affects huge population worldwide. Naturally derived drug discovery has emerged as a potential pathway in search of anticancers. Natural products-based drugs are generally considered safe, compared to their synthetic counterparts. Read More

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November 2018
1 Read

The spectrum of cutaneous adverse events during encorafenib and binimetinib treatment in B-rapidly accelerated fibrosarcoma-mutated advanced melanoma.

J Eur Acad Dermatol Venereol 2018 Nov 23. Epub 2018 Nov 23.

Department of Dermatology, University Hospital of Zurich, Zurich, Switzerland.

Background: B-rapidly accelerated fibrosarcoma (BRAF) inhibitor encorafenib alone and in combination with MEK inhibitor binimetinib improves survival in BRAF-mutated melanoma patients. So far, the range of cutaneous adverse events has been characterized only for established BRAF inhibitors (vemurafenib, dabrafenib) and MEK inhibitors (trametinib, cobimetinib).

Objective: The aim of this study was to investigate cutaneous adverse events emerging in melanoma patients treated with encorafenib and binimetinib. Read More

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November 2018
3 Reads

Safety of 5α-reductase inhibitors and spironolactone in breast cancer patients receiving endocrine therapies.

Breast Cancer Res Treat 2018 Nov 22. Epub 2018 Nov 22.

Department of Dermatology, Memorial Sloan-Kettering Cancer Center, 16 East 60th Street, Suite 407, 4th Floor, New York, NY, 10022, USA.

Purpose: To provide dermatologists and oncologists with a foundation for practical understanding and uses of 5α-reductase inhibitors and spironolactone for breast cancer patients and survivors receiving endocrine therapies (ETs), including the effect of these treatments on sex hormone levels, any reported drug interactions, and any risk of malignancy.

Methods: All published studies from January 1978 through April 2018 were considered, using databases such as PubMed, Google Scholar, and Science Direct. Forty-seven studies were included in this review. Read More

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November 2018
5 Reads

Comorbidities in Dermatology: What's Real and What's Not.

Dermatol Clin 2019 Jan 1;37(1):65-71. Epub 2018 Nov 1.

Department of Dermatology, George Washington Medical Faculty Associates, 2150 Pennsylvania Avenue Northwest, Suite 2B-427, Washington, DC 20037, USA; Department of Dermatology, George Washington School of Medicine and Health Sciences, 2150 Pennsylvania Avenue Northwest, Suite 2B-427, Washington, DC 20037, USA. Electronic address:

Comorbidities affecting dermatologic patients are of significant importance to providers and highly relevant for appropriate patient counseling, screening practices, prevention, and treatment. This article seeks to highlight several of the newest findings in the literature regarding comorbidities associated with dermatologic diseases including atopic dermatitis, hidradenitis suppurativa, alopecia areata, chronic urticaria, and the pemphigus family of immunobullous diseases. Further investigation is needed for associations between atopic dermatitis and pancreatic cancer and pemphigus family diseases and chronic obstructive pulmonary disease in order to better characterize the strength of these associations and clinical relevance. Read More

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January 2019
3 Reads

Facial and Extrafacial Lesions in an Ethnically Diverse Series of 91 Patients with Frontal Fibrosing Alopecia Followed at a Single Center.

Dermatology 2018 Nov 22:1-8. Epub 2018 Nov 22.

Background: Various facial and extrafacial lesions have been reported in frontal fibrosing alopecia (FFA). Facial papules have been associated with worse prognosis.

Objectives: We sought to detect the prevalence of facial and extrafacial lesions and to analyze their relation to demographic and clinical variables in a large and ethnically diverse series of patients with FFA. Read More

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November 2018
1 Read

Annurca Apple Polyphenols Protect Murine Hair Follicles from Taxane Induced Dystrophy and Hijacks Polyunsaturated Fatty Acid Metabolism toward β-Oxidation.

Nutrients 2018 Nov 20;10(11). Epub 2018 Nov 20.

Department of Pharmacy, University of Naples Federico II. Via Montesano 49, 80149 Naples, Italy.

Chemotherapy-induced alopecia (CIA) is a common side effect of conventional chemotherapy and represents a major problem in clinical oncology. Even months after the end of chemotherapy, many cancer patients complain of hair loss, a condition that is psychologically difficult to manage. CIA disturbs social and sexual interactions and causes anxiety and depression. Read More

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November 2018
3 Reads

Drugs with a stigma: thoughts regarding a recent publication, "One of the Best Treatments for Alopecia Areata Remains Unpublished".

Int J Dermatol 2019 Jan 21;58(1):126-127. Epub 2018 Nov 21.

Professor and Chairman (Emeritus) of Dermatology and Immunology, Vargas School of Medicine, Central University of Venezuela, Caracas, Venezuela.

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January 2019
2 Reads

Prevalence of alopecia in gray seals Halichoerus grypus atlantica in Massachusetts, USA, 2004-2013.

Dis Aquat Organ 2018 Nov;131(3):167-176

Rescue and Rehabilitation Department, New England Aquarium, Boston, MA 02110, USA.

There has been an increase in the presence of alopecia among gray seals Halichoerus grypus atlantica in Massachusetts, USA. To understand the prevalence and describe the presentation of this condition, data records and photographs of 10070 gray seals from 2004-2013 were reviewed; there were sufficient data to confidently assess the presence or absence of alopecia in 2134 seals. Mild hair loss presented in multifocal patches with minimal to no skin lesions or erythema. Read More

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November 2018
3 Reads

An early diagnosis of trichorhinophalangeal syndrome type 1: a case report and a review of literature.

Ital J Pediatr 2018 Nov 20;44(1):138. Epub 2018 Nov 20.

Division of Pediatric Endocrinology, Meyer University Children's Hospital, University of Florence, Florence, Italy.

Background: Trichorhinophalangeal syndrome (TRPS) is a rare autosomal dominant disorder caused by defects involving the TRPS1 gene. It exhibits distinctive craniofacial, ectodermal and skeletal abnormalities, such as sparse hair, bulbous nasal tip and short deformed fingers, with extremely variable expressivity.

Case Presentation: We report the case of a 17 months old girl, who presented growth retardation and dysmorphic features. Read More

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November 2018
1 Read

Frontal pattern hair loss among Chinese women is frequently associated with ponytail hairstyle.

Dermatol Ther 2018 Nov 20:e12784. Epub 2018 Nov 20.

University of Rome ("G. Marconi"), Rome, Italy.

Female alopecia patients in China often present with a frontal pattern hair loss. This feature is seen less frequently in western women. Women in China frequently style their hair in a ponytail. Read More

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November 2018
1 Read

Hair Loss Prevention by a Scalp Cooling Device in Early Breast Cancer Patients: the Poliambulanza Preliminary Experience.

Rev Recent Clin Trials 2018 Nov 19. Epub 2018 Nov 19.

Medical Oncology Unit, Fondazione Poliambulanza - Brescia. Italy.

Background: The most effective agents in the treatment of breast cancer have as common side effect the hair loss. Some studies reported a reduction of hair loss with the use of the scalp cooling device. Indeed, it decreases the drug accumulation in the hair follicles. Read More

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November 2018
8 Reads

Functional Subunit Reconstruction of Giant Facial Congenital Melanocytic Nevi in Children With the Use of Matriderm and Skin Graft: Surgical Experience and Literature Review.

Eplasty 2018 5;18:e30. Epub 2018 Oct 5.

Plastic and Reconstructive Surgery Section, Department of Surgery, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.

Facial giant congenital melanocytic nevus represents a major cosmetic deformity for the child and parents and is a challenge for the plastic surgeons to achieve best cosmetic results. Herein, we present a case of single-stage surgical reconstruction using partial-thickness scalp skin graft aided with Matriderm dermal substitute for a facial giant congenital melanocytic nevus. An 8-year-old boy presented with a facial giant congenital melanocytic nevus without leptomeningeal involvement. Read More

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October 2018
4 Reads

Fluconazole-Induced Alopecia: Examination in an animal model and human cohort.

Antimicrob Agents Chemother 2018 Nov 19. Epub 2018 Nov 19.

Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis.

Fluconazole-induced alopecia is a significant problem for patients receiving long-term therapy. We evaluated the hair-cycle changes of fluconazole in a rat model and investigated potential molecular mechanisms. Plasma and tissue levels of retinoic acid were not found causal. Read More

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November 2018
3 Reads