6,471 results match your criteria Allgemeine Forst Und Jagdzeitung[Journal]


[Rare Cause for Difficulty in Swallowing with Neck Swelling - Paraganglioma].

Praxis (Bern 1994) 2020 Jul;109(9):736-742

Allgemeine Innere Medizin, Medbase St. Gallen am Vadianplatz, St. Gallen.

Rare Cause for Difficulty in Swallowing with Neck Swelling - Paraganglioma Pain-free lateral swelling of the neck should be taken seriously and promptly clarified by using sonography. If a cervical paraganglioma is suspected, an interdisciplinary clarification should be initiated. In addition to an MRI of the neck, a vascular-surgical, an ENT specialist and an endocrinological examination should be carried out. Read More

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http://dx.doi.org/10.1024/1661-8157/a003476DOI Listing

[CME Sonography 91/Answers: Differential Diagnosis of Lower Abdominal Pain].

Praxis (Bern 1994) 2020 Jul;109(9):695-696

Ultrasound Learning Center (ULC) der European Federation of Ultrasound in Medicine and Biology (EFSUMB) am Institut für Allgemeine Innere Medizin und Nephrologie, Klinik Hirslanden, Zürich.

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http://dx.doi.org/10.1024/1661-8157/a003474DOI Listing

[Development and Evaluation of an Acceptance and Commitment Therapy (ACT)-Based Group Intervention for Cancer Patients with Psychological Burden].

Psychother Psychosom Med Psychol 2020 Jul 7. Epub 2020 Jul 7.

Klinik für Allgemeine Innere Medizin und Psychosomatik, UniversitätsKlinikum Heidelberg.

Objective: Cancer is associated with many psychosocial stressors that lead to high psychological distress in over 50% of patients. About one third of patients make use of psycho-oncological services. Acceptance and Commitment Therapy (ACT), a transdiagnostic approach of the third wave of cognitive behavioral therapy, represents a promising approach for psycho-oncological interventions. Read More

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http://dx.doi.org/10.1055/a-1174-0283DOI Listing

Blood carbon dioxide tension and risk in pulmonary arterial hypertension.

Int J Cardiol 2020 Jul 4. Epub 2020 Jul 4.

Abteilung für Pneumologie, II. Medizinische Klinik und Poliklinik, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany.

Background: Low partial pressure of blood carbon dioxide (PCO) is common in patients with pulmonary arterial hypertension (PAH) and may inform on clinical outcomes. We investigated whether PCO measurements could provide prognostic information in addition to standard risk assessment in this group of patients.

Methods: We conducted a retrospective observational cohort study on patients with newly diagnosed idiopathic, heritable or drug/toxin-induced PAH recruited from two European centres. Read More

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http://dx.doi.org/10.1016/j.ijcard.2020.06.069DOI Listing

Communications via the Small Leucine-rich Proteoglycans: Molecular Specificity in Inflammation and Autoimmune Diseases.

J Histochem Cytochem 2020 Jul 6:22155420930303. Epub 2020 Jul 6.

Pharmazentrum Frankfurt/ZAFES, Institut für Allgemeine Pharmakologie und Toxikologie, Klinikum der Johann Wolfgang Goethe-Universität Frankfurt am Main, Frankfurt am Main, Germany.

Inflammation is a highly regulated biological response of the immune system that is triggered by assaulting pathogens or endogenous alarmins. It is now well established that some soluble extracellular matrix constituents, such as small leucine-rich proteoglycans (SLRPs), can act as danger signals and trigger aseptic inflammation by interacting with innate immune receptors. SLRP inflammatory signaling cascade goes far beyond its canonical function. Read More

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http://dx.doi.org/10.1369/0022155420930303DOI Listing

[Periprosthetic fractures of the acetabulum: osteosynthesis].

Chirurg 2020 Jul 2. Epub 2020 Jul 2.

Centrum für Muskuloskeletale Chirurgie, Charité - Universitätsmedizin Berlin, Berlin, Deutschland.

In most cases periprosthetic fractures of the acetabulum are complex injuries and are extremely challenging for the treating medical team. Over the years the frequency of this overall rare entity has increased due to demographic changes. In recent years several treatment algorithms were published and provided the possibility of developing standardized treatment concepts. Read More

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http://dx.doi.org/10.1007/s00104-020-01228-1DOI Listing

[Erratum to: Increased risk of deep vein thrombosis in intensive care unit patients with CoViD-19 infections?-Preliminary data].

Chirurg 2020 07;91(7):586-587

Gefäßchirurgie und endovaskuläre Chirurgie, Medizinische Fakultät, Universität Augsburg, Stenglinstraße 2, 86156, Augsburg, Deutschland.

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http://dx.doi.org/10.1007/s00104-020-01245-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322217PMC

[Imminent fracture of the tibia due to an osteolytic lesion caused by an intraosseous tenosynovial giant cell tumor : An unusual clinico-histopathological constellation].

Orthopade 2020 Jun 25. Epub 2020 Jun 25.

Klinik für Allgemeine Orthopädie und Tumororthopädie, Universitätsklinikum Münster, Albert-Schweitzer Campus 1, 48149, Münster, Deutschland.

The tenosynovial giant cell tumor is a rare disease of the joint mucosa, tendon sheaths and bursa. We report on the rare constellation of an intraosseous manifestation of the proximal tibia of a lower leg stump after Burgess amputation as a result of a locally uncontrollable tenosynovial giant cell tumor of the upper ankle. The curettage of the local findings and operative stabilization through an intramedullary composite osteosynthesis led to an early rehabilitation of the exoprosthesis care with regaining patient autonomy. Read More

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http://dx.doi.org/10.1007/s00132-020-03936-2DOI Listing

[Postinfectious reactive arthritis after chlamydia infection in competitive sports : Clinical management and current literature review].

Orthopade 2020 Jun 24. Epub 2020 Jun 24.

Klinik für Allgemeine Orthopädie und Tumororthopädie, Universitätsklinikum Münster, Albert-Schweitzer Campus 1, 48149, Münster, Deutschland.

Background: Reactive arthritis following infection with chlamydia is a rare but important differential diagnosis in atraumatic joint swelling. A delayed diagnosis often leads to prolonged periods of absence from physical activity. This can have serious consequences, especially for the career of competitive athletes. Read More

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http://dx.doi.org/10.1007/s00132-020-03935-3DOI Listing

[Hemoadsorption for blood purification-incomparability of clinically available procedures].

Med Klin Intensivmed Notfmed 2020 Jun 24. Epub 2020 Jun 24.

Abteilung für Anästhesiologie und Intensivmedizin, Traumazentrum Wien, Standort Meidling, Meidling, Österreich.

Background: In the field of intensive care medicine, but also increasingly in cardiac surgery, the use of adsorptive blood purification technologies for the treatment of hyperinflammatory conditions is becoming progressively more important. In addition to the CytoSorb concept, which is more and more clinically accepted and currently the most frequently used method, other companies-particularly from China-have recently entered the market with similar concepts.

Objectives: Given this, the aim of this article is to analyze the different aspects of the various hemoadsorption products offered on the market today and to take a critical look at the available evidence. Read More

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http://dx.doi.org/10.1007/s00063-020-00702-2DOI Listing

[Iodine-induced thyroid dysfunction].

Med Klin Intensivmed Notfmed 2020 Jun 24. Epub 2020 Jun 24.

Klinik für Allgemeine Innere Medizin, Endokrinologie, Diabetologie, Infektiologie, Klinikum Bielefeld Mitte, Bielefeld, Deutschland.

Background: Iodine-induced thyroid dysfunctions are, despite their rare occurrence, important clinical syndromes. Their immediate recognition can avoid serious consequences. Important triggers can be iodine-containing contrast agents, amiodarone or iodine-containing disinfectants. Read More

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http://dx.doi.org/10.1007/s00063-020-00699-8DOI Listing

Compound Formation in Language Mixing.

Front Psychol 2020 3;11:1021. Epub 2020 Jun 3.

Institute of English and American Studies, English Linguistics, Humboldt-Universität zu Berlin, Berlin, Germany.

In this paper, I discuss nominal compound formation in language contact situations, the question being of how compounding in language mixing can inform both theories of mixing and theories of word-hood. This contributes to our further understanding of how word formation operates in cases of language mixing and what exactly is being mixed in mixing, i.e. Read More

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http://dx.doi.org/10.3389/fpsyg.2020.01021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283911PMC

Allergen immunotherapy in the current COVID-19 pandemic: A position paper of AeDA, ARIA, EAACI, DGAKI and GPA: Position paper of the German ARIA Group in cooperation with the Austrian ARIA Group, the Swiss ARIA Group, German Society for Applied Allergology (AEDA), German Society for Allergology and Clinical Immunology (DGAKI), Society for Pediatric Allergology (GPA) in cooperation with AG Clinical Immunology, Allergology and Environmental Medicine of the DGHNO-KHC and the European Academy of Allergy and Clinical Immunology (EAACI).

Allergol Select 2020 28;4:44-52. Epub 2020 May 28.

German ARIA Group.

No abstract available. Read More

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http://dx.doi.org/10.5414/ALX02147EDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304289PMC

Seizure protein 6 controls glycosylation and trafficking of kainate receptor subunits GluK2 and GluK3.

EMBO J 2020 Jun 22:e103457. Epub 2020 Jun 22.

German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.

Seizure protein 6 (SEZ6) is required for the development and maintenance of the nervous system, is a major substrate of the protease BACE1 and is linked to Alzheimer's disease (AD) and psychiatric disorders, but its molecular functions are not well understood. Here, we demonstrate that SEZ6 controls glycosylation and cell surface localization of kainate receptors composed of GluK2/3 subunits. Loss of SEZ6 reduced surface levels of GluK2/3 in primary neurons and reduced kainate-evoked currents in CA1 pyramidal neurons in acute hippocampal slices. Read More

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http://dx.doi.org/10.15252/embj.2019103457DOI Listing

After the game is before the game!

GMS J Med Educ 2020 15;37(3):Doc36. Epub 2020 Apr 15.

Universitätsklinik für Allgemeine Innere Medizin und Psychosomatik, Sektion Psychotraumatologie, Heidelberg, Germany.

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http://dx.doi.org/10.3205/zma001329DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291381PMC

Missing the boat: fatal ending to a missed case of Charcot arthropathy.

Endocrinol Diabetes Metab Case Rep 2020 Jun 16;2020. Epub 2020 Jun 16.

Kantonsspital Sankt Gallen, Klinik für Allgemeine Innere Medizin/Hausarztmedizin, Sankt Gallen, Switzerland.

Summary: Acute Charcot neuropathic osteoarthropathy (CN) is a clinical entity which can easily go unrecognized in its acute early stages due to lack of awareness and unspecific presentation. However, missing early diagnosis can lead to severe complications. We present the case of a 72-year-old male patient who went through the natural course of the disease unnoticed before the very eyes of his physicians leading to a tragic end. Read More

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http://dx.doi.org/10.1530/EDM-20-0013DOI Listing

Contrast-Enhanced Ultrasound: Development of Syllabus for Core Theoretical and Practical Competencies.

Ultrasound Med Biol 2020 Jun 15. Epub 2020 Jun 15.

Department of Respiratory Medicine, Odense University Hospital, Odense C, Denmark; Department of Clinical Research, University of Southern Denmark, Odense C, Denmark.

Contrast-enhanced ultrasound (CEUS) is dependent on the observer's competencies, and thus, appropriate education and testing of individual competency is essential. The current international curriculum in CEUS is methodologically weak and lacks validated competency assessment tests. In this study, we aimed to develop a syllabus for core competencies in CEUS using the Delphi process and an international panel of experts. Read More

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http://dx.doi.org/10.1016/j.ultrasmedbio.2020.05.011DOI Listing

[Level of personality functioning and attachment style as predictors of the successful referral to outpatient psychotherapy].

Z Psychosom Med Psychother 2020 Jun;66(2):178-192

Zentrum für Psychosoziale Medizin der Universität Heidelberg Klinik für Allgemeine Innere Medizin und Psychosomatik Thibautstrasse 4 D-69115 Heidelberg Deutschland Zentrum für Psychosoziale Medizin der Universität Heidelberg.

Outpatient psychotherapy is a key element in the effective treatment of mental health problems. First results suggest that interpersonal problems lead to difficulties in receiving outpatient psychotherapeutic treatment. The relationship between these difficulties, attachment style, and the level of personality functioning is still unclear. Read More

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http://dx.doi.org/10.13109/zptm.2020.66.2.178DOI Listing

Analysis of extracellular matrix composition in the visceral muscles of mutant larvae in .

MicroPubl Biol 2020 May 17;2020. Epub 2020 May 17.

Justus-Liebig-Universität Giessen, Institut für Allgemeine und Spezielle Zoologie, Allgemeine Zoologie und Entwicklungsbiologie.

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http://dx.doi.org/10.17912/micropub.biology.000251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252342PMC

[Prerequisites of magnetic resonance imaging for treatment planning in locally advanced rectal cancer - Interdisciplinary recommendations].

Z Gastroenterol 2020 Jun 16;58(6):577-582. Epub 2020 Jun 16.

Interdisziplinäres Tumorzentrum, Universitätsmedizin Mannheim.

For the purpose of indication and patient stratification of perioperative treatment of locally advanced rectal cancer, magnetic resonance imaging (MRI) has become indispensable. In this report, we describe the importance of MRI diagnostics and the qualitative conditions. Read More

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http://dx.doi.org/10.1055/a-1085-6874DOI Listing

[New insights into diagnostics and therapy of personality disorders-Changes in ICD-11].

Nervenarzt 2020 Jun 15. Epub 2020 Jun 15.

Klinik für Allgemeine Psychiatrie, Universitätsklinikum Heidelberg, Voßstr. 2, 69115, Heidelberg, Deutschland.

Personality disorders (PD) occur frequently and show high remission rates in the long term, while psychosocial recovery remains unsuccessful in a substantial proportion of cases. In ICD-11 the traditional view that PDs have a high stability is abandoned. Instead, the minimum duration is 2 years. Read More

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http://dx.doi.org/10.1007/s00115-020-00936-7DOI Listing

Analytical and Sensory Characterization of the Stereoisomers of 3-Mercaptocycloalkanones and 3-Mercaptocycloalkanols.

J Agric Food Chem 2020 Jul 26;68(27):7184-7193. Epub 2020 Jun 26.

Lehrstuhl für Allgemeine Lebensmitteltechnologie, Technische Universität München, Maximus-von-Imhof-Forum 2, D-85354 Freising-Weihenstephan, Germany.

3-Mercaptocycloalkanones and 3-mercaptocycloalkanols (chain lengths C5-C7) were obtained by addition of thioacetic acid to the respective 2-cycloalken-1-ones and subsequent enzyme-mediated hydrolysis and reduction with LiAlH, respectively. The stereoisomers were separated via capillary gas chromatography using chiral stationary phases. Their configurations were determined based on H NMR data and enzyme-catalyzed kinetic resolutions. Read More

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http://dx.doi.org/10.1021/acs.jafc.0c03113DOI Listing

A reanalysis of the center for epidemiological studies depression scale (CES-D) using non-parametric item response theory.

Psychiatry Res 2020 May 29;290:113132. Epub 2020 May 29.

Department of Psychosomatic Medicine and Psychotherapy, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany; Department of Medical Psychology and Medical Sociology, University of Leipzig, Germany.

The "Center for Epidemiological Studies Depression Scale" (CES-D; Radloff, 1977) is a questionnaire used world-wide to measure depressive symptoms. Although the original four-factor-structure has been widely accepted and replicated, some studies point to other factor-structures like a one- and two-factor-structure. The goal of the current study was to evaluate the factor structure of the CES-D (one-, two- and four-factor-structure), which was found using classical test theory (CTT), with two non-parametric item-response-theory-models (Mokken-Scaling; Monotone-homogeneity-model; MHM and Double-monotonicity-model; DMM). Read More

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http://dx.doi.org/10.1016/j.psychres.2020.113132DOI Listing

Psoriasis 2.0: Facebook als Quelle krankheitsbezogener Informationen für Patienten mit Psoriasis.

J Dtsch Dermatol Ges 2020 Jun;18(6):571-581

Technische Universität München, Fakultät für Medizin, Klinik und Poliklinik für Dermatologie und Allergologie, München, Deutschland.

Hintergrund Und Ziele: Das Internet ist eine gängige Informationsquelle bezüglich gesundheitlicher Themen. Soziale Medien ermöglichen es Patienten mit Psoriasis, Informationen über ihre Erkrankung zu suchen und auszutauschen. Ihre Nutzung geht jedoch auch mit Risiken wie Fehlinformation und Neid einher. Read More

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http://dx.doi.org/10.1111/ddg.14070_gDOI Listing

[Introduction of an Ultrasound Course Based on Peer-Tutoring - An Update on the Blended Learning Basic Course Sonography].

Praxis (Bern 1994) 2020 ;109(8):577-582

Sektion Young Sonographers, Schweizerische Gesellschaft für Ultraschall in der Medizin (SGUM).

Introduction of an Ultrasound Course Based on Peer-Tutoring - An Update on the Blended Learning Basic Course Sonography Following the introduction of the new Swiss learning objectives catalogue 'PROFILES', the ability to carry out simple ultrasound examinations has become mandatory for undergraduates. Thanks to a collaboration between the Bern Institute of Primary Health Care and the 'Young Sonographers' SGUM section, the SGUM's classic-format basic abdomen teaching module has been changed into a 'blended learning' teaching format with 'peer tutoring'. It is particularly intended for students and junior doctors. Read More

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http://dx.doi.org/10.1024/1661-8157/a003494DOI Listing
January 2020

[CME Sonography 91: Differential Diagnosis of Lower Abdominal Pain].

Praxis (Bern 1994) 2020 ;109(8):652-657

Ultrasound Learning Center (ULC) der European Federation of Ultrasound in Medicine and Biology (EFSUMB) am Institut für Allgemeine Innere Medizin und Nephrologie, Klinik Hirslanden, Zürich.

CME Sonography 91: Differential Diagnosis of Lower Abdominal Pain Pain in the lower abdomen is a frequent reason for further imaging clarification by sonography. The most frequent causes are appendicitis and diverticulitis, in addition to ureteral stones, ovarian and tubal pathology as well as various hernias. Appendicitis has a characteristic clinical presentation and can be diagnosed by CT or ultrasound. Read More

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http://dx.doi.org/10.1024/1661-8157/a003473DOI Listing
January 2020

Current Opinion about Hepatocellular Carcinoma <10 mm.

Digestion 2020 Jun 9:1-7. Epub 2020 Jun 9.

Department Allgemeine Innere Medizin (DAIM), Kliniken Hirslanden Beau Site, Salem und Permanence, Bern, Switzerland,

Background: Early detection of hepatocellular carcinoma (HCC) is important. Advances in liver imaging techniques have facilitated the detection of HCC at an early stage. However, there is a controversial discussion on how to diagnose very small HCC by imaging. Read More

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http://dx.doi.org/10.1159/000507923DOI Listing

Bericht aus dem Vorstand.

Neuropsychiatr 2020 Jun;34(2):95

Allgemeine Psychiatrische Abteilung, Krankenanstalt Rudolfstiftung, Juchgasse 25/Haus 22, 1030, Wien, Österreich.

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http://dx.doi.org/10.1007/s40211-020-00353-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276955PMC

[An Update on the Epidemiological Situation of Alveolar Echinococcosis: Recording and Reporting Structures in Austria, Switzerland and Germany].

Gesundheitswesen 2020 Jun 8. Epub 2020 Jun 8.

Klinische Abteilung für Infektionen und Tropenmedizin, Medizinische Universität Wien Universitätsklinik für Innere Medizin I, Wien, Austria.

Objective:  Alveolar echinococcosis (AE) is a rare disease in Austria, Switzerland and Germany (DACh) caused by an infection with the parasite Echinococcus multilocularis. The aim of the study was to describe differences in the detection and reporting systems of alveolar echinococcosis in Austria, Switzerland and Germany and to describe epidemiological trends.

Methodology:  As part of an epidemiological update on 6 September 2019 in Ulm, Germany, experts and representatives discussed differences in the reporting and recording systems as well as the current epidemiological situation. Read More

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http://dx.doi.org/10.1055/a-1138-0692DOI Listing

[All internal segmental transport in tibial bone defects: first experiences with the PRECICE bone transport system].

Unfallchirurg 2020 Jun 5. Epub 2020 Jun 5.

Klinik für Allgemeine, Unfall- und Wiederherstellungschirurgie, Klinikum der Universität München, Ludwig-Maximilians-Universität München, Marchioninistr. 15, 81377, München, Deutschland.

Bone loss of the distal tibia represents a major challenge for the treating surgeons and the reconstruction technique. This is particularly true for septic bone loss. Several techniques are available, ranging from callus distraction of Ilizarov frames and monorail techniques as well as transport with plates and nails; however, implants for internal segmental transport for bone defects have so far not been available. Read More

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http://dx.doi.org/10.1007/s00113-020-00827-1DOI Listing

[Increased risk of deep vein thrombosis in intensive care unit patients with CoViD-19 infections?-Preliminary data].

Chirurg 2020 Jul;91(7):588-594

Gefäßchirurgie und endovaskuläre Chirurgie, Medizinische Fakultät, Universität Augsburg, Stenglinstraße 2, 86156, Augsburg, Deutschland.

Background: The incidence of deep vein thrombosis (DVT) in CoViD-19 patients in intensive care units (ICU) has so far been investigated in only a few studies. Prospective comparative studies with non-CoViD-19 ICU patients are completely lacking.

Objective: Evaluation of the incidence of DVT in ICU patients with CoViD-19 compared to non-CoViD-19 ICU patients who were treated in the University Hospital Augsburg during the same period. Read More

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http://dx.doi.org/10.1007/s00104-020-01222-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274071PMC

[Best supportive care in a young patient with locally advanced MSI-high colon cancer?]

Z Gastroenterol 2020 Jun 5. Epub 2020 Jun 5.

Klinik für Gastroenterologie, Hepatologie und Endokrinologie, Medizinische Hochschule Hannover.

Molecular diagnostics are increasingly important to guide treatment decisions in oncologic patients. For instance, the presence of high-grade microsatellite-instability (MSI-high) is considered to be one of the major positive predictors of therapy response to immune-checkpoint inhibitors in patients with solid tumors. Based on impressive results from several immune-oncology trials, the American Food and Drug Administration (FDA) granted approval to immunotherapy in any previously treated, MSI-high solid cancer in 2017. Read More

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http://dx.doi.org/10.1055/a-1174-0732DOI Listing

[Robot-assisted Minimally Invasive Oesophagectomy (RAMIE) - Setup, Port Placement, Stepwise Procedure Guide].

Zentralbl Chir 2020 Jun 4;145(3):252-259. Epub 2020 Jun 4.

Klinik für Allgemeine-, Viszeral-, Thorax-, Transplantations- und Kinderchirurgie, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Deutschland.

Robot-assisted minimally invasive oesophagectomy (RAMIE) can overcome the limitations of thoracoscopic surgery, particularly in the thoracic part of the operation. Thanks to more degrees of freedom of movement, anastomosis is simpler in the robotic procedure. In this work, we present our established full RAMIE-technique on the da Vinci Xi system. Read More

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http://dx.doi.org/10.1055/a-1149-2247DOI Listing

[Stressors for patients in the intensive care unit : An analysis taking controllability into consideration].

Anaesthesist 2020 Jun 2. Epub 2020 Jun 2.

Klinik für Anästhesiologie und Intensivmedizin, Universität zu Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Deutschland.

Objective: Studies on stress factors for patients in intensive care units (ICU) have so far concentrated on whether certain stressors have occurred or how stressful they were. There are no studies on stress for patients in ICUs that measured both the perception of stress and the chances perceived to control it; however, loss of control can result in long-term psychopathological consequences, such as depression or posttraumatic stress disorder. Therefore, a questionnaire was developed to evaluate the influence of controllability on perception of stress. Read More

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http://dx.doi.org/10.1007/s00101-020-00798-3DOI Listing

LI-RADS ancillary features on contrast-enhanced ultrasonography.

Ultrasonography 2020 Jul 9;39(3):221-228. Epub 2020 May 9.

Department of Radiology, Université de Montréal, Montreal, Canada.

The Liver Imaging Reporting and Data System (LI-RADS) was created to standardize liver imaging in patients at high risk for hepatocellular carcinoma (HCC), and it uses a diagnostic algorithm to assign categories that reflect the relative probability of HCC, non-HCC malignancies, or benign focal liver lesions. In addition to major imaging features, ancillary features (AFs) are used by radiologists to refine the categorization of liver nodules. In the present document, we discuss and explain the application of AFs currently defined within the LI-RADS guidelines. Read More

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http://dx.doi.org/10.14366/usg.19052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315297PMC

[Renal Monomorphology in COVID-19 with Acute Renal Insufficiency].

Praxis (Bern 1994) 2020 Jul 29;109(9):731-735. Epub 2020 May 29.

Ultrasound Learning Center (ULC) der European Federation of Ultrasound in Medicine and Biology (EFSUMB) am Institut für Allgemeine Innere Medizin und Nephrologie, Klinik Hirslanden, Zürich.

Renal Monomorphology in COVID-19 with Acute Renal Insufficiency A 78-year-old ventilator-dependent COVID-19 patient developed severe renal failure with an estimated glomerular filtration rate of 20 ml/min per 1.73 m2 and nephrotic proteinuria. Sonography showed echo-dense and enlarged kidneys with high resistance indices (>0. Read More

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http://dx.doi.org/10.1024/1661-8157/a003526DOI Listing

[Tumor vaccines-therapeutic vaccination against cancer].

Internist (Berl) 2020 Jul;61(7):690-698

Interfakultäres Institut für Zellbiologie (IFIZ), Abteilung Immunologie, Eberhard Karls Universität Tübingen, Auf der Morgenstelle 15, 72076, Tübingen, Deutschland.

Tumor cells always exhibit differences to normal cells. These differences can be recognized by the immune system, enabling the destruction of tumor cells by T cells, as was impressively demonstrated by the success of immune checkpoint inhibition, e.g. Read More

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http://dx.doi.org/10.1007/s00108-020-00814-zDOI Listing

Cognitive modelling reveals distinct electrophysiological markers of decision confidence and error monitoring.

Neuroimage 2020 May 24;218:116963. Epub 2020 May 24.

Katholische Universität Eichstätt-Ingolstadt, Fakultät für Psychologie und Pädagogik, Lehrstuhl für Allgemeine Psychologie, Eichstätt, Germany.

Is confidence in perceptual decisions generated by the same brain processes as decision itself, or does confidence require metacognitive processes following up on the decision? In a masked orientation task with varying stimulus-onset-asynchrony, we used EEG and cognitive modelling to trace the timing of the neural correlates of confidence. Confidence reported by human observers increased with stimulus-onset-asynchrony in correct and to a lesser degree in incorrect trials, a pattern incompatible with established models of confidence. Electrophysiological activity was associated with confidence in two different time periods, namely 350-500 ​ms after stimulus onset and 250-350 ​ms after the response. Read More

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http://dx.doi.org/10.1016/j.neuroimage.2020.116963DOI Listing

[Percutaneous liver biopsy before organ removal-Impact on organ allocation and costs in liver transplantation].

Chirurg 2020 May 19. Epub 2020 May 19.

Klinik für Allgemeine, Viszeral- und Transplantationschirurgie, Universitätsklinikum Tübingen, Tübingen, Deutschland.

Background: The value and safety of percutaneous liver biopsy (PLB) in brain-dead donors before organ removal and its impact on organ allocation and costs of liver transplantation (LT) in the Eurotransplant (ET) region is still a matter of ongoing debate.

Material And Methods: A PLB was performed in 36 brain-dead organ donors. The complication rate, ultrasonography findings, macroscopic evaluation and histological results of PLB and donor characteristics were analyzed. Read More

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http://dx.doi.org/10.1007/s00104-020-01192-wDOI Listing

Commentary on the World Federation for Ultrasound in Medicine and Biology Project "Incidental Findings".

Ultrasound Med Biol 2020 Jul 12;46(7):1815-1820. Epub 2020 May 12.

Department of Internal Medicine, Krankenhaus Märkisch Oderland, Strausberg/Wriezen and Brandenburg Institute for Clinical Ultrasound, Neuruppin, Germany.

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http://dx.doi.org/10.1016/j.ultrasmedbio.2020.02.002DOI Listing

Hydroxychloroquine as an aerosol might markedly reduce and even prevent severe clinical symptoms after SARS-CoV-2 infection.

Med Hypotheses 2020 Apr 27;142:109783. Epub 2020 Apr 27.

Vitos Klinikum Hochtaunus, Friedrichsdorf, Germany; Goethe-Universität Frankfurt am Main, Abt. Allgemeine Psychologie II, Germany.

Covid-19 is a new coronavirus disease first described in December 2019. This respiratory illness is severe and potentially fatal. Severe cases make up to 15%, lethality ranges between 1. Read More

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http://dx.doi.org/10.1016/j.mehy.2020.109783DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185016PMC

Cystic echinococcosis, review and illustration of non-hepatic manifestations.

Med Ultrason 2020 Apr 8. Epub 2020 Apr 8.

Department of Ultrasound, Zhongshan Hospital, Fudan University, Shanghai, China.

Cystic echinococcosis (CE) or hydatidosis (hydatid cysts), is an infection with a wide spectrum of manifestations, from asymptomatic infection to fatal disease. Ultrasound (US) allows screening, diagnosis, differential diagnosis, treatment guidance and follow-up of CE under many circumstances. Hydatid cysts are predominantly observed in the liver but many other organs can be involved. Read More

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http://dx.doi.org/10.11152/mu-2537DOI Listing

Medical Student Ultrasound Education, a WFUMB Position Paper, Part II. A consensus statement of ultrasound societies.

Med Ultrason 2020 May;22(2):220-229

Department Allgemeine Innere Medizin (DAIM), Kliniken Hirslanden Beau Site, Salem und Permanence, Bern, Switzerland Ultrasound Department, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Ultrasound is becoming a fundamental first-line diagnostic tool for most medical specialties and an innovative tool to teach anatomy, physiology and pathophysiology to undergraduate and graduate students. However, availability of structured training programs during medical school is lagging behind and many physicians still acquire all their ultrasound skills during postgraduate training.There is wide variation in medical student ultrasound education worldwide. Read More

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http://dx.doi.org/10.11152/mu-2599DOI Listing

Lindavia intermedia (Bacillariophyceae) and Nuisance lake Snow in New Zealand: Chitin Content and Quantitative PCR Methods to Estimate Cell Concentrations and Expression of Chitin Synthase.

J Phycol 2020 May 12. Epub 2020 May 12.

Department of Zoology, University of Otago, P.O. Box 56, Dunedin, 9054, New Zealand.

Lake snow, caused by the freshwater centric diatom Lindavia intermedia, has become problematic in several large, oligotrophic New Zealand lakes over the past decade. Macroaggregates produced by L. intermedia foul fishing lines, intake screens, and water filters, and have a negative impact on recreational values. Read More

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http://dx.doi.org/10.1111/jpy.13014DOI Listing

[Recommendations for gene therapy of spinal muscular atrophy with onasemnogene abeparvovec-AVXS-101 : Consensus paper of the German representatives of the Society for Pediatric Neurology (GNP) and the German treatment centers with collaboration of the medical scientific advisory board of the German Society for Muscular Diseases (DGM)].

Nervenarzt 2020 Jun;91(6):518-529

Abteilung Neuropädiatrie und Sozialpädiatrisches Zentrum, Zentrum für Kinderheilkunde, Universitätsklinikum Bonn, Bonn, Deutschland.

Background: Spinal muscular atrophy (SMA) is a severe, life-limiting neurodegenerative disease. A disease-modifying and approved therapy with nusinersen has been available in Germany since July 2017. Gene therapies offer another promising treatment option through a once in a lifetime administration. Read More

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http://dx.doi.org/10.1007/s00115-020-00919-8DOI Listing

[Quality of indications in bariatric surgery].

Chirurg 2020 May 8. Epub 2020 May 8.

Klinik für Allgemein‑, Viszeral- und Transplantationschirurgie, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Deutschland.

Bariatric and metabolic surgery is increasingly being utilized in Germany and also worldwide. Due to the increased perioperative risk compared to non-obese patients, a detailed and accurate preoperative assessment of the patient is pivotal to improve postoperative and long-term outcomes. The indications for bariatric surgery have shifted in recent years from a certain body mass index (BMI) to comorbidity-based indications. Read More

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http://dx.doi.org/10.1007/s00104-020-01183-xDOI Listing

Fungal RNA editing: who, when, and why?

Authors:
Ines Teichert

Appl Microbiol Biotechnol 2020 Jul 7;104(13):5689-5695. Epub 2020 May 7.

General and Molecular Botany, Ruhr-University Bochum, 44780, Bochum, Germany.

RNA editing occurs in all kingdoms of life and in various RNA species. The editing of nuclear protein-coding transcripts has long been known in metazoans, but was only recently detected in fungi. In contrast to many metazoan species, fungal editing sites occur mostly in coding regions, and therefore, fungal editing can change protein sequences and lead to modified or new functions of proteins. Read More

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http://dx.doi.org/10.1007/s00253-020-10631-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306014PMC

First In-Human Medical Imaging with a PASylated Zr-Labeled Anti-HER2 Fab-Fragment in a Patient with Metastatic Breast Cancer.

Nucl Med Mol Imaging 2020 Apr 20;54(2):114-119. Epub 2020 Apr 20.

5Klinikum rechts der Isar, Technische Universität München, 81675 Munich, Germany.

Purpose: PASylation® offers the ability to systematically tune and optimize the pharmacokinetics of protein tracers for molecular imaging. Here we report the first clinical translation of a PASylated Fab fragment (Zr∙Df-HER2-Fab-PAS) for the molecular imaging of tumor-related HER2 expression.

Methods: A patient with HER2-positive metastatic breast cancer received 37 MBq of Zr∙Df-HER2-Fab-PAS at a total mass dose of 70 μg. Read More

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http://dx.doi.org/10.1007/s13139-020-00638-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198682PMC

Calculated parenteral initial treatment of bacterial infections: Economic aspects of antibiotic treatment.

GMS Infect Dis 2020 26;8:Doc03. Epub 2020 Mar 26.

Klinische Pharmazie, Apotheke des Universitätsklinikums Augsburg, Germany.

This is the seventeenth chapter of the guideline "Calculated initial parenteral treatment of bacterial infections in adults - update 2018" in the 2 updated version. The German guideline by the Paul-Ehrlich-Gesellschaft für Chemotherapie e.V. Read More

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http://dx.doi.org/10.3205/id000047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186923PMC