12,225 results match your criteria Allergy[Journal]


House dust mite drives pro-inflammatory eicosanoid reprogramming and macrophage effector functions.

Allergy 2018 Dec 16. Epub 2018 Dec 16.

Center of Allergy and Environment (ZAUM), Technical University of Munich and Helmholtz Center Munich, member of the German Center for Lung Research, 80802, Munich, Germany.

Background: Eicosanoid lipid mediators play key roles in type 2 immune responses, e.g. in allergy and asthma. Read More

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December 2018

Data-driven adult asthma phenotypes based on clinical characteristics are associated with asthma outcomes twenty years later.

Allergy 2018 Dec 13. Epub 2018 Dec 13.

Inserm, Univ. Grenoble Alpes, CNRS, IAB, Team of environmental epidemiology applied to reproduction and respiratory health, 38000, Grenoble, France.

Background: Research based on cluster analyses led to the identification of particular phenotypes confirming phenotypic heterogeneity of asthma. The long-term clinical course of asthma phenotypes defined by clustering analysis remains unknown, although it is a key aspect to underpin their clinical relevance. We aimed to estimate risk of poor asthma events between asthma clusters identified 20 years earlier. Read More

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December 2018

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Arerugi 2018 ;67(10):1416-1417

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January 2018

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Arerugi 2018 ;67(10):1414-1415

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January 2018

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Arerugi 2018 ;67(10):1412-1413

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January 2018

[EARLY INTERVENTION FOR THE DEVELOPMENT OF ATOPIC DERMATITIS].

Authors:
Kenta Horimukai

Arerugi 2018 ;67(10):1405-1411

The Jikei University Katsushika Medical Center.

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January 2018

[AN UPDATE ON DIAGNOSIS AND MANAGEMENT OF DRUG ALLERGY].

Authors:
Michiko Aihara

Arerugi 2018 ;67(10):1399-1404

Department of Environmental Immuno-Dermatology, Yokohama City University Graduate School of Medicine.

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January 2018

[JAPANESE GUIDELINES FOR DIAGNOSIS AND TREATMENT OF URTICARIA 2018].

Authors:
Michihiro Hide

Arerugi 2018 ;67(10):1394-1398

Department of Dermatology, Institute of Biomedical and Health Sciences, Hiroshima University.

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January 2018

[THE BRIEF COMMENTARY ON GUIDELINES FOR THE MANAGEMENT OF ATOPIC DERMATITIS 2018].

Authors:
Hidehisa Saeki

Arerugi 2018 ;67(10):1388-1393

Department of Dermatology, Nippon Medical School.

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January 2018

[ALLERGIC RHINITIS・CHRONIC RHINOSINUSITIS].

Arerugi 2018 ;67(10):1379-1386

Department of Otorhinolaryngology, Faculty of Medical Science, University of Fukui.

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January 2018

[FOOD ALLERGY].

Arerugi 2018 ;67(10):1368-1378

Department of Pediatrics, Sagamihara National Hospital.

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January 2018

Much ado about Biologicals:Highlights of the Master Class on Biologicals, Prague, 2018.

Allergy 2018 Dec 2. Epub 2018 Dec 2.

First Faculty of Medicine of Charles University and Thomayer Hospital, Department of Respiratory Medicine, Prague, Czech Republic.

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December 2018

Chemically modified peanut extract shows increased safety while maintaining immunogenicity.

Allergy 2018 Dec 2. Epub 2018 Dec 2.

Institute for Risk Assessment Sciences, Immunotoxicology, Utrecht University, Utrecht, The Netherlands.

Background: Peanuts are most responsible for food-induced anaphylaxis in adults in developed countries. An effective and safe immunotherapy is urgently needed. The aim of this study was to investigate the immunogenicity, allergenicity and immunotherapeutic efficacy of a well characterized chemically modified peanut extract (MPE) adsorbed to Al(OH) . Read More

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December 2018

Smoking habits among adolescents with asthma - data from a population based birth cohort.

Allergy 2018 Dec 4. Epub 2018 Dec 4.

Department of Clinical Science and Education Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.

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December 2018
2 Reads

IL-27 Signaling Deficiency Develops Th17-enhanced Th2-dominant Inflammation in Murine Allergic Conjunctivitis Model.

Allergy 2018 Dec 4. Epub 2018 Dec 4.

Ocular Surface Center, Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, Texas, USA.

Background: While most studies focus on pro-allergic cytokines, the protective role of immunosuppressive cytokines in allergic inflammation is not well elucidated. This study was to explore a novel anti-inflammatory role and cellular/molecular mechanism of IL-27 in allergic inflammation.

Methods: A murine model of experimental allergic conjunctivitis (EAC) was induced in BALB/c, C57BL/6 or IL-27Rα deficient (WSX-1 ) mice by short ragweed pollen, with untreated or PBS-treated mice as controls. Read More

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December 2018
1 Read

Emerging concepts and challenges in implementing the exposome paradigm in allergic diseases and asthma.

Allergy 2018 Dec 4. Epub 2018 Dec 4.

UNC School of Medicine, Chapel Hill, USA.

Exposome research can improve the understanding of the mechanistic connections between exposures and health to help mitigate adverse health outcomes across the lifespan. The exposomic approach provides a risk profile instead of single predictors and thus is particularly applicable to allergic diseases and asthma. Under the PRACTALL collaboration between the European Academy of Allergy and Clinical Immunology (EAACI) and the American Academy of Allergy, Asthma and Immunology (AAAAI) we evaluated the current concepts and the unmet needs on the role of the exposome in allergic diseases and asthma. Read More

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December 2018
2 Reads

The WHO/IUIS Allergen Nomenclature.

Allergy 2018 Dec 4. Epub 2018 Dec 4.

Institute of Pathophysiology and Allergy Research, Medical University of Vienna, Vienna, Austria.

The WHO/IUIS Allergen Nomenclature Sub-Committee (http://www.allergen.org/), an international body of experts, has developed an allergen nomenclature system to provide a common language for unambiguous communications between researchers, clinicians, pharmaceutical companies and regulatory authorities regarding specific allergenic proteins. Read More

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December 2018

Long-term outcomes in chronic hypersensitivity pneumonitis.

Allergy 2018 Dec 4. Epub 2018 Dec 4.

Servicio de Neumología, Departamento de Medicina, Hospital Universitario Vall d'Hebron, Universidad Autónoma de Barcelona, Cataluña, España.

Introduction: The objective of this study was to analyze mortality, possible predictors of long-term survival and health-related quality of life of a large chronic hypersensitivity pneumonitis (CHP) patient sample.

Methods: Longitudinal study in patients diagnosed with CHP during 2004-2013, followed for at least one year. Patients remaining alive and consenting to participate had a follow-up visit during 2015, including a complete pulmonary function study and the EuroQol-5D and Beck Depression and Anxiety Inventories. Read More

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December 2018
10 Reads

Long term effects upon rituximab treatment of acquired angio-edema due to c1-inhibitor deficiency.

Allergy 2018 Nov 29. Epub 2018 Nov 29.

Clinical Immunology and Allergy, Royal National Throat Nose and Ear Hospital, University College London Hospitals, London.

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November 2018

Dupilumab reduces local type 2 pro-inflammatory biomarkers in chronic rhinosinusitis with nasal polyposis.

Allergy 2018 Nov 28. Epub 2018 Nov 28.

Division of ENT Diseases, Department of Clinical Sciences, Intervention and Technology, Karolinska Institute, Stockholm, Sweden.

Background: Chronic rhinosinusitis with nasal polyposis (CRSwNP) is a type 2-mediated inflammatory disease associated with significant clinical, social, and economic burdens and high unmet therapeutic need. Dupilumab, a fully human monoclonal antibody targeting the interleukin-4 receptor α (IL-4Rα) subunit, demonstrated efficacy and acceptable safety in CRSwNP and other type 2 diseases (e.g. Read More

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November 2018

Der p 1-specific regulatory T cell response during house dust mite allergen immunotherapy.

Allergy 2018 Nov 28. Epub 2018 Nov 28.

Swiss Institute of Allergy and Asthma Research, University of Zurich, Switzerland.

Background: Allergen-specific immunotherapy (AIT) is the only available treatment for allergic diseases that can induce specific immune tolerance to allergens. The key mechanisms involved in this process include changes in allergen-specific regulatory T (Treg) cells.

Methods: We studied 25 allergic rhinitis patients undergoing subcutaneous house dust mite-specific immunotherapy. Read More

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November 2018
8 Reads
6.028 Impact Factor

Omalizumab discontinuation in children with severe allergic asthma: an observational real life study.

Allergy 2018 Nov 27. Epub 2018 Nov 27.

Normandie Univ, UNIROUEN Inserm EA 2656, Rouen University Hospital, Pediatric Respiratory Disease and Allergy Unit Hospital, F76000, Rouen, France.

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November 2018

Skin disorders are prominent features in primary immunodeficiency diseases: a systematic overview of current data.

Allergy 2018 Nov 27. Epub 2018 Nov 27.

Department of Dermatology.

Primary immunodeficiency diseases (PIDs) are characterized by an increased risk of infections, autoimmunity, autoinflammation, malignancy and allergic disorders. Skin disorders are also common clinical features in PIDs and may be among the presenting manifestations. Recognition of specific PID-associated skin conditions in combination with other clinical features as described in the currently used warning signs could raise suspicion of an underlying PID. Read More

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November 2018
3 Reads

Increased expression of L-plastin in nasal polyp of patients with nonsteroidal anti-inflammatory drug exacerbated respiratory disease.

Allergy 2018 Nov 26. Epub 2018 Nov 26.

Division of Otorhinolaryngology Head and Neck Surgery, Department of Sensory and Locomotor Medicine.

Background: Most patients with nonsteroidal anti-inflammatory drug exacerbated respiratory disease (NERD) suffer from recurrence of nasal polyps. However, little is known about the specific cellular and molecular mechanisms contributing to the pathogenesis of nasal polyp development in patients with NERD in particular, especially at baseline when cyclooxygenase 1 inhibitors are not present. The objectives of this study were to identify proteins involved in the pathogenesis of nasal polyps in patients with NERD. Read More

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November 2018
3 Reads

How to discontinue omalizumab in chronic spontaneous urticaria?

Allergy 2018 Nov 26. Epub 2018 Nov 26.

Division of Allergy and Clinical Immunology, Department of Chest Diseases, Erciyes University School of Medicine, Kayseri, Turkey.

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November 2018
2 Reads

All items of the Food Allergy Quality of Life Questionnaires are relevant for peanut-allergic patients.

Allergy 2018 Nov 26. Epub 2018 Nov 26.

University of Groningen, University Medical Center Groningen, Department of General Practice, Groningen, the Netherlands.

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November 2018

CCR10 ILC2s with ILC1-like properties exhibit a protective function in severe allergic asthma.

Allergy 2018 Nov 26. Epub 2018 Nov 26.

Research Departement, Stallergenes Greer, Antony, France.

Background: We previously showed that patients with severe allergic asthma have high numbers of circulating ILC2s expressing CCR10.

Method: Herein, CCR10 ILC2s were further analyzed in the blood of healthy individuals or patients with allergic and non-allergic asthma. Characteristics of human CCR10 and CCR10 ILC2s were assessed by flow cytometry as well as single-cell multiplex RT-qPCR. Read More

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November 2018

RNA is taking its Toll - Impact of RNA-specific Toll-like receptors on health and disease.

Allergy 2018 Nov 26. Epub 2018 Nov 26.

Division of Innate Immunity, Research Center Borstel- Leibniz Lung Center, Borstel, Germany.

RNA-sensing Toll-like receptors (TLRs) are often described as anti-viral receptors of the innate immune system. However, the past decade has shown that the function and importance of these receptors is far more complex. These receptors were found to be relevant for the detection of various bacterial, archaeal, and eukaryotic microorganisms and facilitate the discrimination between dead and living microbes. Read More

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November 2018
2 Reads

Association between asthma, rhinitis and conjunctivitis multimorbidities with molecular IgE sensitization in adults.

Allergy 2018 Nov 25. Epub 2018 Nov 25.

INSERM, U1168, VIMA: Aging and chronic diseases. Epidemiological and Public health approaches, F-94807, Villejuif, France.

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November 2018
1 Read

Authors:

Arerugi 2018 ;67(9):1283-1285

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January 2018
1 Read

Authors:

Arerugi 2018 ;67(9):1281-1282

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January 2018
1 Read

Authors:

Arerugi 2018 ;67(9):1279-1280

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January 2018

[ROLE OF GLUTATHIONE REDOX IN ALLERGIC DISEASES].

Arerugi 2018 ;67(9):1273-1278

Department of Internal Medicine, Kiryu Kosei General Hospital.

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January 2018

[ASTHMA AND MENTAL STRESS].

Arerugi 2018 ;67(9):1269-1272

Division of Respiratory Medicine, Niigata University Greduate School of Medicine and Dental Science.

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January 2018
1 Read

[ASTHMA PREVENTION AND MANAGEMENT GUIDELINE 2018].

Authors:
Jun Tamaoki

Arerugi 2018 ;67(9):1263-1268

Tokyo Women's Medical University.

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January 2018
6 Reads

[TOPICS 2017 IN BRONCHIAL ASTHMA].

Authors:
Arihiko Kanehiro

Arerugi 2018 ;67(9):1248-1256

Allergy and Respiratory Disease Center, Japan Organization of Occupational Health and Safety Okayama Rosai Hospital.

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January 2018
1 Read

[ALLERGIC SKIN DISORDERS].

Authors:
Norito Katoh

Arerugi 2018 ;67(9):1243-1247

Dermatology, Kyoto Prefectural University of Medicine Graduate School of Medical Science.

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January 2018
2 Reads

Bacillus subtilis exopolysaccharide prevents allergic eosinophilia.

Allergy 2018 Nov 20. Epub 2018 Nov 20.

Microbiology and Immunology, Loyola University Chicago, Maywood, Illinois.

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November 2018
2 Reads

Corrigendum.

Authors:

Allergy 2018 Nov;73(11):2264

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November 2018

In this Issue: Graphical Abstracts.

Authors:

Allergy 2018 Nov;73(11):2103-2106

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November 2018

Disentangling the heterogeneity of allergic respiratory diseases by latent class analysis reveals novel phenotypes.

Allergy 2018 Nov 17. Epub 2018 Nov 17.

CINTESIS - Center for Health Technology and Services Research, Faculty of Medicine, University of Porto, Porto, Portugal.

Background: Refined phenotyping of allergic diseases may unravel novel phenotypes. Conjunctivitis as an independent disorder has never been approached.

Aim: To identify distinct classes of allergic respiratory diseases using latent class analysis (LCA) and distinguish each class using classification and regression tree (CART) analysis. Read More

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November 2018
6 Reads

Prostaglandin E decrease in induced sputum of hypersensitive asthmatics during oral challenge with aspirin.

Allergy 2018 Nov 17. Epub 2018 Nov 17.

Department of Internal Medicine, Jagiellonian University School of Medicine, Cracow, Poland.

Background: A special regulatory role for prostaglandin E (PGE ) has been postulated in nonsteroidal anti-inflammatory drug (NSAID)-exacerbated respiratory disease (NERD).

Objective: To investigate the effect of systemic aspirin (acetylsalicylic acid) administration on airway PGE biosynthesis in induced sputum supernatant (ISS) among subjects with NERD or aspirin-tolerant asthma with chronic rhinosinusitis with nasal polyposis (ATA-CRSwNP), as well as healthy controls (HC).

Methods: Induced sputum (IS) was collected from patients with NERD (n = 26), ATA-CRSwNP (n = 17), and HC (n = 21) at baseline and after aspirin challenge. Read More

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November 2018
6 Reads

Cord-serum per- and poly-fluoroalkyl substances and atopy and eczema at 12-months.

Allergy 2018 Nov 14. Epub 2018 Nov 14.

Allergy and Lung Health Unit, Melbourne School of Population and Global Health, University of Melbourne, Parkville, Victoria, Australia.

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November 2018
5 Reads