1,131 results match your criteria Allergology International[Journal]


Biological treatments for severe asthma: A major advance in asthma care.

Authors:
William W Busse

Allergol Int 2019 Feb 18. Epub 2019 Feb 18.

Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA. Electronic address:

Asthma is a heterogeneous disease with considerable variability noted in disease severity, patterns of airway inflammation, and achievement of disease control on current medications. An absence of disease control is most frequently noted in patients with severe asthma, and is defined as a lack of control while on high dose inhaled corticosteroids (ICS) plus a second controller medication. In part, this lack of control may relate to a diminished effect of current guideline-directed care on the existing pattern of airway inflammation in severe asthma. Read More

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http://dx.doi.org/10.1016/j.alit.2019.01.004DOI Listing
February 2019

Forced oscillation technique may identify asthma-COPD overlap.

Allergol Int 2019 Feb 7. Epub 2019 Feb 7.

Division of Respiratory Medicine, Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.alit.2019.01.002DOI Listing
February 2019
2 Reads

Association between chemical components of PM and children's primary care night-time visits due to asthma attacks: A case-crossover study.

Allergol Int 2019 Feb 7. Epub 2019 Feb 7.

Himeji Medical Association, Himeji, Japan.

Background: Few papers have examined the association between the chemical components of PM and health effects. The existence of an association is now under discussion.

Methods: This case-crossover study aimed to examine the association between the chemical components of PM and night-time primary care visits (PCVs) due to asthma attacks. Read More

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http://dx.doi.org/10.1016/j.alit.2019.01.001DOI Listing
February 2019
1 Read

Urban/rural residence effect on emergency department visits arising from food-induced anaphylaxis.

Allergol Int 2019 Feb 5. Epub 2019 Feb 5.

Department of Pediatrics and Adolescent Medicine, Juntendo University, School of Medicine, Tokyo, Japan.

Background: Anaphylaxis is a severe and potentially fatal allergic response. Early-life exposure to rural environments may help protect against allergic reaction. This study assesses urban/rural differences by age and race/ethnicity in emergency department (ED) pediatric visit rates for food-induced anaphylaxis. Read More

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http://dx.doi.org/10.1016/j.alit.2018.12.007DOI Listing
February 2019
2 Reads

Acute inflammatory and immunologic responses against antigen in chronic bird-related hypersensitivity pneumonitis.

Allergol Int 2019 Feb 5. Epub 2019 Feb 5.

Department of Respiratory Medicine, Tokyo Medical and Dental University, Tokyo, Japan. Electronic address:

Background: Hypersensitivity pneumonitis (HP) is an immune-mediated lung disease induced by the inhalation of a wide variety of antigens and a persistent antigen exposure induces inevitably pulmonary fibrosis in chronic HP. Although neutrophils, Th1 and Th17 cells contribute to lung inflammation in acute phase of HP, there is no clear explanation as to how the immunological reaction occurs just after the inhalation of causative antigens in the chronic phase of HP.

Methods: We examined the inflammatory and immunologic profiles before and after the inhalation provocation test (IPT) in serum and bronchoalveolar lavage fluid (BALF) from patients with chronic bird-related HP (BRHP) and other interstitial lung diseases (ILDs). Read More

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http://dx.doi.org/10.1016/j.alit.2018.12.010DOI Listing
February 2019
1 Read

Development of conjunctivitis with a conjunctival proliferative lesion in a patient treated with dupilumab for atopic dermatitis.

Allergol Int 2019 Feb 1. Epub 2019 Feb 1.

Department of Ophthalmology and Visual Science, Kochi Medical School, Kochi University, Kochi, Japan.

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http://dx.doi.org/10.1016/j.alit.2018.12.012DOI Listing
February 2019

A very rare case of allergy to beluga caviar.

Allergol Int 2019 Jan 30. Epub 2019 Jan 30.

St Anthony's Hospital, North Cheam, Surrey, UK. Electronic address:

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http://dx.doi.org/10.1016/j.alit.2018.12.009DOI Listing
January 2019

Development of a liquid chromatography-tandem mass spectrometry method for quantification of the egg allergen ovalbumin in rat plasma.

Allergol Int 2019 Jan 30. Epub 2019 Jan 30.

Department of Pharmaceutical Services, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.alit.2018.12.005DOI Listing
January 2019

Age-related changes in serum periostin level in allergic and non-allergic children.

Allergol Int 2019 Jan 30. Epub 2019 Jan 30.

Department of Pediatrics, Osaka City University Graduate School of Medicine, Osaka, Japan.

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http://dx.doi.org/10.1016/j.alit.2018.12.006DOI Listing
January 2019

Case series of allergic bronchopulmonary aspergillosis treated successfully and safely with long-term mepolizumab.

Allergol Int 2019 Jan 28. Epub 2019 Jan 28.

Department of Allergy and Respiratory Medicine, The Fraternity Memorial Hospital, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.alit.2018.12.008DOI Listing
January 2019
2 Reads

Allergic bronchopulmonary aspergillosis in succession to chronic eosinophilic pneumonia.

Allergol Int 2019 Jan 19. Epub 2019 Jan 19.

Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.alit.2018.12.004DOI Listing
January 2019
1 Read

Food allergy is linked to season of birth, sun exposure, and vitamin D deficiency.

Allergol Int 2019 Jan 19. Epub 2019 Jan 19.

Department of Allergy, Aichi Children's Health and Medical Center, Aichi, Japan.

The season of birth and ultraviolet B exposure have been related to the occurrence of food allergy. The levels of vitamin D produced from skin by ultraviolet B exposure might reflect this relationship. Vitamin D is known to induce antimicrobial peptides, protect intestinal flora, enhance the gut epithelial barrier, suppress mast cell activation and IgE synthesis from B cells, and increase the number of tolerogenic dendritic cells and IL-10-producing regulatory T cells. Read More

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http://dx.doi.org/10.1016/j.alit.2018.12.003DOI Listing
January 2019
1 Read

Severe asthma in children: Evaluation and management.

Allergol Int 2019 Jan 12. Epub 2019 Jan 12.

Harvard Medical School, Boston, MA, USA; Division of Allergy and Immunology, Boston Children's Hospital, Boston, MA, USA. Electronic address:

Severe asthma in children is associated with significant morbidity. Children with severe asthma are at increased risk for adverse outcomes including medication-related side effects, life-threatening exacerbations, and impaired quality of life. It is important to differentiate between severe therapy resistant asthma and difficult-to-treat asthma due to comorbidities. Read More

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http://dx.doi.org/10.1016/j.alit.2018.11.007DOI Listing
January 2019
3 Reads

Thermography: High sensitivity and specificity diagnosing contact dermatitis in patch testing.

Allergol Int 2018 Dec 28. Epub 2018 Dec 28.

Department of Dermatology, University Hospital Zurich, Zurich, Switzerland; Faculty of Medicine, University of Zurich, Zurich, Switzerland; Competence Center Personalized Medicine, University of Zurich and ETH Zurich, Zurich, Switzerland. Electronic address:

Background: Patch testing of contact allergens to diagnose allergic contact dermatitis (ACD) is a traditional, useful tool. The most important decision is the distinction between allergic and irritant reactions, as this has direct implications on diagnosis and management. Our objective was to evaluate a new method of non-contact infrared reading of patch tests. Read More

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http://dx.doi.org/10.1016/j.alit.2018.12.001DOI Listing
December 2018
3 Reads

New trends in mucosal immunology and allergy.

Allergol Int 2019 Jan;68(1):1-3

Division of Medical Biochemistry, Department of Biomolecular Sciences, Saga Medical School, Saga, Japan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S13238930183016
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http://dx.doi.org/10.1016/j.alit.2018.12.002DOI Listing
January 2019
7 Reads

Non-type 2 inflammation in severe asthma is propelled by neutrophil cytoplasts and maintained by defective resolution.

Allergol Int 2018 Dec 17. Epub 2018 Dec 17.

Pulmonary and Critical Care Medicine Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address:

Asthma is a highly prevalent heterogeneous inflammatory disorder of the airways. Not all patients respond to anti-inflammatory treatment with corticosteroids, leading to significant morbidity in severe asthma. Much attention has been paid to defining the cellular and molecular mechanisms of type 2 inflammation that are operative in asthma. Read More

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http://dx.doi.org/10.1016/j.alit.2018.11.006DOI Listing
December 2018
1 Read

Intestinal absorption of the wheat allergen gliadin in rats.

Allergol Int 2018 Dec 14. Epub 2018 Dec 14.

Department of Pharmaceutical Services, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.

Background: Aspirin enhances food allergy symptoms by increasing absorption of ingested allergens. The objective of this study is to elucidate the role of aspirin in facilitating intestinal absorption of the wheat allergen, gliadin, in rats.

Methods: Plasma concentrations of gliadin were determined after oral administration by gavage or administration into a closed intestinal loop in rats. Read More

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http://dx.doi.org/10.1016/j.alit.2018.11.005DOI Listing
December 2018
2 Reads

The Urticaria Control Test and Urticaria Activity Score correlate with quality of life in adult Japanese patients with chronic spontaneous urticaria.

Allergol Int 2018 Dec 4. Epub 2018 Dec 4.

Division of Dermatology, Department of Internal Related, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S13238930183015
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http://dx.doi.org/10.1016/j.alit.2018.11.003DOI Listing
December 2018
7 Reads

Bird-egg syndrome induced by α-livetin sensitization in a budgerigar keeper: Successful induction of tolerance by avoiding exposure to avians.

Allergol Int 2018 Dec 4. Epub 2018 Dec 4.

Department of Environmental Immuno-Dermatology, Yokohama City University School of Medicine, Yokohama, Japan.

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http://dx.doi.org/10.1016/j.alit.2018.11.004DOI Listing
December 2018
1 Read

Obesity and severe asthma.

Allergol Int 2018 Nov 30. Epub 2018 Nov 30.

Department of Environmental Health, Harvard University T.H. Chan School of Public Health, Boston, MA, USA. Electronic address:

Obesity is an important global health issue for both children and adults. Obesity increases the prevalence and incidence of asthma and also increases the risk for severe asthma. Here we describe the features of severe asthma phenotypes for which obesity is a defining characteristic, including steroid resistance, airway inflammation, and co-morbidities. Read More

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http://dx.doi.org/10.1016/j.alit.2018.10.004DOI Listing
November 2018
2 Reads

Airway innate lymphoid cells in the induction and regulation of allergy.

Allergol Int 2019 Jan 23;68(1):9-16. Epub 2018 Nov 23.

Department of Medicine, University of California, San Diego, CA, USA. Electronic address:

The recent discovery of innate lymphoid cells has revolutionized our understanding of the pathogenesis of immune diseases including allergy and asthma. Innate lymphoid cells (ILCs) are a heterogeneous collection of lymphocytes that lack antigen-specificity (non-T, non-B cells) and potently produce characteristic cytokines of T cell subsets (Th1, Th2, Th17). ILCs are divided into group 1 (ILC1s), group 2 (ILC2s), or group 3 (ILC3s). Read More

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http://dx.doi.org/10.1016/j.alit.2018.11.001DOI Listing
January 2019
7 Reads

Obesity, but not metabolic syndrome, as a risk factor for late-onset asthma in Japanese women.

Allergol Int 2018 Nov 22. Epub 2018 Nov 22.

Clinical Research Center for Allergy and Rheumatology, Sagamihara National Hospital, Sagamihara, Japan.

Background: Several cross-sectional studies have suggested an association between obesity and asthma. However, few studies have investigated this relationship longitudinally, especially in middle-aged subjects. Although metabolic syndrome is a well-known risk factor for many non-communicable diseases, its contribution to asthma remains controversial. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13238930183015
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http://dx.doi.org/10.1016/j.alit.2018.10.003DOI Listing
November 2018
11 Reads

Critical role of platelets in the production of thymus and activation-regulated chemokine in children: A case series study.

Allergol Int 2018 Nov 20. Epub 2018 Nov 20.

Department of Pediatrics, KKR Sapporo Medical Center, Sapporo, Japan.

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http://dx.doi.org/10.1016/j.alit.2018.11.002DOI Listing
November 2018
1 Read

Bidirectional roles of IL-22 in the pathogenesis of allergic airway inflammation.

Allergol Int 2019 Jan 10;68(1):4-8. Epub 2018 Nov 10.

Department of Allergy and Clinical Immunology, Graduate School of Medicine, Chiba University, Chiba, Japan. Electronic address:

Asthma is the most prevalent allergic disease of the airway, which is characterized by eosinophilic inflammation, mucus hyperproduction, and airway hyper-responsiveness. Although these pathognomonic features are mainly mediated by antigen-specific Th2 cells and their cytokines, such as IL-4, IL-5, and IL-13, recent studies have revealed that other inflammatory cells, including Th17 cells and innate lymphoid cells (ILCs), also play a critical role in the pathogenesis of asthma. IL-22, one of the cytokines produced by Th17 cells and type 3 ILCs, has distinct functional properties, as IL-22 exclusively acts on non-hematopoietic cells including epithelial cells of mucosal surface and exhibits a broad range of action in regeneration and host protection. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13238930183014
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http://dx.doi.org/10.1016/j.alit.2018.10.002DOI Listing
January 2019
12 Reads

Periostin deletion suppresses late-phase response in mouse experimental allergic conjunctivitis.

Allergol Int 2018 Nov 9. Epub 2018 Nov 9.

Laboratory of Ocular Atopic Diseases, Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan. Electronic address:

Background: To investigate the potential roles of periostin (POSTN), an extracellular matrix preferentially expressed in Th2-skewed conditions in the pathophysiology of allergic conjunctivitis.

Methods: The roles of POSTN in ragweed-induced experimental allergic conjunctivitis (RW-EAC) were evaluated using both POSTN-knockout (KO) and congenic BALB/c wild-type mice. Histological analysis was carried out to enumerate eosinophils/basophils in the conjunctival tissue. Read More

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http://dx.doi.org/10.1016/j.alit.2018.09.007DOI Listing
November 2018
2 Reads

Efficacy and safety of rupatadine in Japanese patients with seasonal allergic rhinitis: A double-blind, randomized, multicenter, placebo-controlled clinical trial.

Allergol Int 2018 Oct 31. Epub 2018 Oct 31.

Teikoku Seiyaku Co., Ltd., Kagawa, Japan.

Background: Rupatadine is a novel non-sedating second-generation H-antihistamine with antiplatelet-activating factor activity, first marketed in Spain in 2003. It is used for treating allergic rhinitis in more than 80 countries. This study investigated its efficacy and safety in Japanese patients with seasonal allergic rhinitis (SAR). Read More

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http://dx.doi.org/10.1016/j.alit.2018.08.011DOI Listing
October 2018
5 Reads

A comprehensive understanding of the gut mucosal immune system in allergic inflammation.

Allergol Int 2019 Jan 23;68(1):17-25. Epub 2018 Oct 23.

Department of Mucosal Immunology, IMSUT Distinguished Professor Unit, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan; International Research and Development Center for Mucosal Vaccines, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan; Division of Gastroenterology, Department of Medicine, CU-UCSD Center for Mucosal Immunology, Allergy and Vaccines, University of California San Diego, San Diego, CA, USA; Division of Comparative Pathology and Medicine, Department of Pathology, University of California San Diego, San Diego, CA, USA. Electronic address:

Despite its direct exposure to huge amounts of microorganisms and foreign and dietary antigens, the gut mucosa maintains intestinal homeostasis by utilizing the mucosal immune system. The gut mucosal immune system protects the host from the invasion of infectious pathogens and eliminates harmful non-self antigens, but it allows the cohabitation of commensal bacteria in the gut and the entry of dietary non-self antigens into the body via the mucosal surface. These physiological and immunological activities are regulated by the ingenious gut mucosal immune network, comprising such features as gut-associated lymphoid tissue, mucosal immune cells, cytokines, chemokines, antimicrobial peptides, secretory IgA, and commensal bacteria. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13238930183014
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http://dx.doi.org/10.1016/j.alit.2018.09.004DOI Listing
January 2019
17 Reads

Identification of biomarkers for predicting the response to cyclosporine A therapy in patients with chronic spontaneous urticaria.

Allergol Int 2018 Oct 22. Epub 2018 Oct 22.

Allergy and Immunology Research Project Team, Research Institute of Medical Science, Nihon University School of Medicine, Tokyo, Japan; Center for Institutional Research and Medical Education, Nihon University School of Medicine, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.alit.2018.09.006DOI Listing
October 2018
3 Reads

Reduced nasal nitric oxide levels in patients with eosinophilic chronic rhinosinusitis.

Allergol Int 2018 Oct 19. Epub 2018 Oct 19.

Division of Otorhinolaryngology Head and Neck Surgery, Department of Sensory and Locomotor Medicine, University of Fukui, Fukui, Japan.

Background: In Eosinophilic chronic rhinosinusitis (ECRS), it is difficult to estimate the refractoriness and recurrence risk for each patient. Fraction of exhaled nitric oxide (FeNO) is known as a biomarker of eosinophilic inflammation in lower airway. It has been reported that nasal NO has some crucial functions in the upper and lower airways. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13238930183014
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http://dx.doi.org/10.1016/j.alit.2018.09.005DOI Listing
October 2018
3 Reads

SEMA4A promotes eosinophil survival and contributes to eosinophil-mediated allergic diseases.

Allergol Int 2018 Oct 17. Epub 2018 Oct 17.

Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Graduate School of Medicine, Osaka, Japan; Laboratory of Immunopathology, World Premier International Immunology Frontier Research Center, Osaka, Japan; Integrated Frontier Research for Medical Science Division, The Institute for Open and Transdisciplinary Research Initiatives (OTRI), Osaka, Japan.

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http://dx.doi.org/10.1016/j.alit.2018.10.001DOI Listing
October 2018
2 Reads

Efficacy of a short pretreatment with omalizumab in children with anaphylaxis to hymenoptera venom immunotherapy: A report of three cases.

Allergol Int 2018 Oct 17. Epub 2018 Oct 17.

AP-HP, Hôpital Necker-Enfants Malades, Service de Pneumologie et d'Allergologie Pédiatriques, Paris, France; Université Paris Descartes, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.alit.2018.09.003DOI Listing
October 2018
3 Reads

Significance of IgG4-positive cells in severe eosinophilic chronic rhinosinusitis.

Allergol Int 2018 Oct 10. Epub 2018 Oct 10.

Department of Otolaryngology-Head & Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan; Department of Otorhinolaryngology, International University of Health and Welfare School of Medicine, Narita, Japan. Electronic address:

Background: IgG4 production is regulated by type 2 (IL-4 and IL-13) and regulatory (IL-10) cytokines involved in the pathophysiology of chronic rhinosinusitis (CRS). We sought to determine the pathophysiological characteristics of IgG4-positive cells in sinonasal tissues in CRS, especially eosinophilic CRS (ECRS).

Methods: IgG4-positive cells in uncinate tissues (UT) and nasal polyps (NP) were examined by immunohistochemistry. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13238930183013
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http://dx.doi.org/10.1016/j.alit.2018.09.002DOI Listing
October 2018
9 Reads

Accuracy of objective tests for diagnosing adult asthma in symptomatic patients: A systematic literature review and hierarchical Bayesian latent-class meta-analysis.

Allergol Int 2018 Oct 8. Epub 2018 Oct 8.

Department of Respiratory Medicine and Allergology, Kindai University Faculty of Medicine, Osaka, Japan.

Background: We obtain summary estimates of the accuracy of additional objective tests for the diagnosis of adult asthma using systematic review and meta-analysis of diagnostic test accuracy studies.

Methods: Medline, Embase, and other relevant electronic databases were searched for papers published between January 1989 and December 2016. Studies were included if they evaluated the diagnostic accuracy of objective tests, including airway reversibility (AR), airway hyperresponsiveness (AHR), and fractionated exhaled nitric oxide (FeNO) for the diagnosis of adult asthma in patients with symptoms suggestive of asthma. Read More

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http://dx.doi.org/10.1016/j.alit.2018.08.013DOI Listing
October 2018
1 Read

Usefulness of serum biopterin as a predictive biomarker for childhood asthma control: A prospective cohort study.

Allergol Int 2019 Jan 5;68(1):96-100. Epub 2018 Oct 5.

Department of Pediatrics, Osaka City University Graduate School of Medicine, Osaka, Japan.

Background: Pteridines are metabolites of tetrahydrobiopterin, which serves as co-enzyme of nitric oxide synthase. We sought to investigate the usefulness of pteridines as biomarkers for childhood asthma control.

Methods: We conducted a single-center prospective cohort study involving 168 asthmatic children aged 4-17 years who visited the periodical asthma checkup program. Read More

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http://dx.doi.org/10.1016/j.alit.2018.08.012DOI Listing
January 2019
5 Reads

Two facets of sweat: A defensive factor in skin tissues and an accelerating factor for allergic skin diseases.

Allergol Int 2018 Oct;67(4):433-434

Division of Medical Biochemistry, Department of Biomolecular Sciences, Saga Medical School, Saga, Japan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S13238930183012
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http://dx.doi.org/10.1016/j.alit.2018.09.001DOI Listing
October 2018
4 Reads

Severity scales of non-IgE-mediated gastrointestinal food allergies in neonates and infants.

Allergol Int 2018 Sep 22. Epub 2018 Sep 22.

Department of Pediatrics, Gunma University Graduate School of Medicine, Gunma, Japan.

Background: Non-IgE-mediated gastrointestinal food allergies (non-IgE-GI-FAs) are one type of food allergy found in neonates and infants. Few reports have defined the severity of non-IgE-GI-FAs in these populations.

Methods: Grading scales of the severity of non-IgE-GI-FAs according to extra-GI symptoms, such as poor weight gain, as well as systemic symptoms, including fever and shock, were developed and retrospectively applied to patients with non-IgE-GI-FAs. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13238930183010
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http://dx.doi.org/10.1016/j.alit.2018.08.004DOI Listing
September 2018
30 Reads

Ultrasonographic study of intestinal Doppler blood flow in infantile non-IgE-mediated gastrointestinal food allergy.

Allergol Int 2018 Sep 22. Epub 2018 Sep 22.

Department of Pediatrics and Adolescent Medicine, Juntendo University Faculty of Medicine, Tokyo, Japan.

Background: Although non-IgE-mediated gastrointestinal food allergy has increased rapidly in Japan, a small number of reports has evaluated B-mode and Doppler ultrasonographic findings in the acute phase of infantile gastrointestinal milk allergy. The aim of the present study was to compare the diagnostic utility of ultrasonographic findings and laboratory allergic data in non-IgE-mediated infantile gastrointestinal milk allergy.

Methods: Sixteen cases of active non-IgE-mediated infantile gastrointestinal milk allergy, diagnosed by food elimination tests and oral food challenge tests (OFCTs) (group A), 15 cases of acute viral gastroenteritis (AGE) (group B), and 15 controls (group C) were enrolled. Read More

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http://dx.doi.org/10.1016/j.alit.2018.08.010DOI Listing
September 2018
5 Reads

Factors determining parenting stress in mothers of children with atopic dermatitis.

Allergol Int 2018 Sep 11. Epub 2018 Sep 11.

Department of Nursing, Health Development Nursing, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Background: Atopic dermatitis (AD) influences a child's emotional and social well-being, as well as his or her physical health. The influence of AD on the daily lives of parents and caregivers has also been documented. This study examined how parenting stress is affected by demographic background, characteristics of children's AD, and their family systems. Read More

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http://dx.doi.org/10.1016/j.alit.2018.08.006DOI Listing
September 2018
2 Reads

Characteristics of breath sound in infants with risk factors for asthma development.

Allergol Int 2019 Jan 10;68(1):90-95. Epub 2018 Sep 10.

Department of Pediatrics, Tokai University School of Medicine, Kanagawa, Japan.

Background: Breath sound parameters have been suggested as biomarkers of the airway narrowing in children. Using a commercially available breath sound analyzer, the characteristics of the airway condition were investigated in infants with the risk factors for asthma development.

Methods: A total of 443 infants (mean age, 9. Read More

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http://dx.doi.org/10.1016/j.alit.2018.07.011DOI Listing
January 2019
20 Reads

CISH is a negative regulator of IL-13-induced CCL26 production in lung fibroblasts.

Allergol Int 2019 Jan 6;68(1):101-109. Epub 2018 Sep 6.

Department of Respiratory Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Background: Bronchial asthma is a chronic airway disease characterized by eosinophilic airway inflammation. Lung fibroblasts activated by IL-13 serve as important sources of chemokines, such as eotaxins, contributing to persistent eosinophilic inflammation. Src-homology 2-containing protein (CISH), belonging to the suppressor of cytokine signaling (SOCS) family, acts as a negative regulator of cytokine induction. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13238930183010
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http://dx.doi.org/10.1016/j.alit.2018.08.005DOI Listing
January 2019
18 Reads

Preface to the proceedings of the Workshop on Eosinophils in Allergy and Related Diseases 2017.

Authors:
Hiroshi Nakajima

Allergol Int 2018 09;67S:S1-S2

Department of Allergy and Clinical Immunology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba-shi, Chiba 260-8670, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.alit.2018.08.007DOI Listing
September 2018
1 Read

Anaphylaxis to xylitol diagnosed by skin prick test and basophil activation test.

Allergol Int 2019 Jan 3;68(1):130-131. Epub 2018 Sep 3.

Department of Pediatrics, Fujita Health University Hospital, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi 470-1192, Japan.

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http://dx.doi.org/10.1016/j.alit.2018.08.001DOI Listing
January 2019
3 Reads

A case of human seminal plasma allergy sensitized with dog prostatic kallikrein, Can f 5.

Allergol Int 2018 Sep 1. Epub 2018 Sep 1.

Department of Dermatology, Course of Integrated Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan.

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http://dx.doi.org/10.1016/j.alit.2018.08.003DOI Listing
September 2018
1 Read

Sweat is a most efficient natural moisturizer providing protective immunity at points of allergen entry.

Allergol Int 2018 Oct 1;67(4):442-447. Epub 2018 Sep 1.

Department of Dermatology, Kawasaki Medical School, Kurashiki, Japan; Dermatology, Kawasaki Hospital, Okayama, Japan.

Although there is a growing acceptance that sweat could play a detrimental role in various allergic skin diseases, the possibility that sweat is also involved in maintenance of skin hydration and skin-specific immune responses has not been acknowledged. We initially describe physiological role of sweat in both maintaining skin hydration and thermoregulation. The purpose of this article is to provide the reader with objective evidence that sweating is intimately linked to vital stratum corneum barrier function and usefulness of application of moisturizers in clinical care of allergic skin diseases. Read More

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http://dx.doi.org/10.1016/j.alit.2018.07.010DOI Listing
October 2018
2 Reads

Role of whole saliva in the efficacy of sublingual immunotherapy in seasonal allergic rhinitis.

Allergol Int 2019 Jan 27;68(1):82-89. Epub 2018 Aug 27.

Department of Otolaryngology-Head & Neck Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan; Department of Otorhinolaryngology, International University of Health and Welfare School of Medicine, Narita, Japan. Electronic address:

Background: The development of methods to predict the clinical effectiveness of sublingual immunotherapy (SLIT) for allergic diseases is a crucial matter. We sought to determine whether whole saliva, which is the first body component that contacts allergen extracts during SLIT, is associated with the clinical effectiveness of SLIT in Japanese cedar pollinosis.

Methods: Blood monocytes or monocytic THP-1 cells were cultured in the presence or absence of either whole saliva or pure saliva with or without treatments including filtration and blockade of TLR2 and/or TLR4 signaling. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13238930183009
Publisher Site
http://dx.doi.org/10.1016/j.alit.2018.07.008DOI Listing
January 2019
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Central suppressant therapies in unexplained chronic cough patients whose sputum cultures yielded Bjerkandera adusta.

Allergol Int 2019 Jan 23;68(1):125-126. Epub 2018 Aug 23.

Laboratory of Space and Environmental Medicine, Teikyo University, Tokyo, Japan.

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Source
https://linkinghub.elsevier.com/retrieve/pii/S13238930183009
Publisher Site
http://dx.doi.org/10.1016/j.alit.2018.07.009DOI Listing
January 2019
10 Reads