Allergol Immunopathol (Madr) 2018 Feb 19. Epub 2018 Feb 19.
Allergy Unit, Department of Pediatrics, Agostino Gemelli Hospital, Sacred Heart Catholic University, Rome, Italy.
Food protein induced enterocolitis syndrome (FPIES) is classified as non-IgE-mediated or cell-mediated food allergy, although there is an atypical phenotype so defined for the presence of specific IgEs. All diagnostic criteria for FPIES include the absence of skin or respiratory symptoms of IgE-mediated type. We present four cases that suggest that specific IgEs may have a pathogenic role, resulting in the existence of different FPIES phenotypes. Read More