Sci Total Environ 2022 Sep 7;838(Pt 4):156540. Epub 2022 Jun 7.
University of Murcia, Murcia, Spain; Biomedical Research Institute of Murcia (IMIB), Murcia, Spain; "Virgen de la Arrixaca" University Clinical Hospital, Murcia, Spain; Consortium for Biomedical Research in Epidemiology and Public Health (CIBER Epidemiología y Salud Pública, CIBERESP), Instituto de Salud Carlos III, Madrid, Spain.
Endocrine disrupting chemicals (EDCs) set a public health risk through disruption of normal physiological processes. The toxicoepigenetic mechanisms of developmental exposure to common EDCs, such as bisphenol A (BPA), are poorly known. The present study aimed to evaluate associations between perinatal maternal urinary concentrations of BPA, bisphenol S (BPS) and bisphenol F (BPF) and LINE-1 (long interspersed nuclear elements) and Alu (short interspersed nuclear elements, SINEs) DNA methylation levels in newborns, as surrogate markers of global DNA methylation. Read More