11,711 results match your criteria Alimentary Pharmacology and Therapeutics[Journal]


Pathologic Complete Response in a Large Gastric GIST: Using Molecular Markers to Achieve Maximal Response to Neoadjuvant Imatinib.

J Natl Compr Canc Netw 2018 Dec;16(12):1424-1428

Division of Surgical Oncology, Department of Surgical Pathology, Department of Medical Oncology, and Division of Gastroenterology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.

Gastrointestinal stromal tumors (GISTs) represent 1% of alimentary tract neoplasms. Up to 90% of GISTs are driven by activating mutations in tyrosine kinase or α genes. Imatinib mesylate is a tyrosine kinase inhibitor that has recently been used in a neoadjuvant role for locally advanced GIST. Read More

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December 2018

Gut Microbiota, Fusobacteria, and Colorectal Cancer.

Diseases 2018 Dec 11;6(4). Epub 2018 Dec 11.

Department of Pathology, New York University School of Medicine, New York, NY 10016, USA.

The gut microbiota has emerged as an environmental contributor to colorectal cancer (CRC) in both animal models and human studies. It is now generally accepted that bacteria are ubiquitous colonizers of all exposed human body surfaces, including the entire alimentary tract (5). Recently, the concept that a normal bacterial microbiota is essential for the development of inflammation-induced carcinoma has emerged from studies of well-known colonic bacterial microbiota. Read More

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December 2018

Management of postoperative complications may favour the centralization of distal pancreatectomies. Nationwide data on pancreatic distal resections in Finland 2012-2014.

Pancreatology 2018 Nov 30. Epub 2018 Nov 30.

Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland; Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland. Electronic address:

Background: Centralization of pancreatic surgery has proceeded in the last few years in many countries. However, information on the effect of hospital volume specifically on distal pancreatic resections (DP) is lacking.

Aim: To investigate the effect of hospital volume on postoperative complications in DP patients in Finland. Read More

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November 2018

Small-intestinal TG2-specific plasma cells at different stages of coeliac disease.

BMC Immunol 2018 Dec 6;19(1):36. Epub 2018 Dec 6.

Celiac Disease Research Center, Faculty of Medicine and Life Sciences, University of Tampere, P.O. Box 100, 33014, Tampere, Finland.

Background: In coeliac disease, ingestion of gluten induces the production of transglutaminase 2 (TG2)-targeted autoantibodies by TG2-specific plasma cells present at high frequency in the small intestinal mucosa in untreated disease. During treatment with a gluten-free diet (GFD), the number of these cells decreases considerably. It has not been previously investigated whether the cells are also present prior to development of villous atrophy, or in non-responsive patients and those with dietary lapses. Read More

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December 2018

Long biliopancreatic and short alimentary limb results in more weight loss in revisional RYGB surgery. Outcomes of the randomized controlled ELEGANCE REDO trial.

Authors:
Radwan Kassir

Surg Obes Relat Dis 2018 Nov 15. Epub 2018 Nov 15.

University Hospital centre of Saint-Denis (Félix-Guyon) / La Réunion, France. Electronic address:

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November 2018

Silver effects on silkworm, Bombyx mori.

J Toxicol Sci 2018 ;43(12):697-709

School of Food and Biological Engineering, Jiangsu University, China.

Silver nanoparticles (Ag-NPs) are known as a noble metal, and owing to their exclusive properties, their use is widespread in consumer products and they are mostly incorporated into food packaging and food contact products. The aim of this work was to evaluate the effects of direct ingestion of Ag-NPs through food to assess their toxicity effects on the growth and development of silkworms at different concentrations (1 mg·L to 100 mg·L), in addition to the examination of the distribution of Ag-NPs in the silkworm body and midgut histopathological analysis. RNA sequencing was performed to investigate the transcriptomic responses to Ag-NPs exposure. Read More

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January 2018
1 Read

Ingestion of plastic by fish: A comparison of Thames Estuary and Firth of Clyde populations.

Mar Pollut Bull 2018 Dec 4;137:12-23. Epub 2018 Oct 4.

School of Biological Sciences, Royal Holloway University of London, Egham, Surrey TW20 0EX, UK.

This study compared plastic ingestion between pelagic and benthic fish populations from two UK watersheds: the Thames Estuary and the Firth of Clyde. The alimentary canals of 876 individuals were examined. Of twenty-one estuarine species investigated, fourteen ingested plastics, including predator (fish) and prey (shrimp) species. Read More

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December 2018

The importance of the biliopancreatic limb length in gastric bypass: A systematic review.

Surg Obes Relat Dis 2018 Oct 22. Epub 2018 Oct 22.

The Bariatric & Metabolic Institute, Section of Minimally Invasive Surgery, Cleveland Clinic Florida, Weston, Florida. Electronic address:

Background: Bariatric surgery has proven to be the most durable treatment for obesity, and it also provides improvement of obesity's associated co-morbidities. Although several mechanisms for its metabolic effects have been studied, the implications of the surgically constructed anatomy on its functioning physiology have not been elucidated. This leaves some uncertainty regarding the recommended limb lengths in Roux-en-Y gastric bypass. Read More

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October 2018
1 Read

[Considerations for an epidemiology of food and eating: A genealogy of nutritional studies in Ecuador].

Salud Colect 2018 Sep;14(3):607-622

Médico, Cirujano. Candidato a Doctor en Salud Colectiva. Profesor titular, Universidad de Cuenca, Ecuador.

This article analyzes two of the most important studies on nutrition that have been carried out in Ecuador in the last fifty years. The objective is to justify the need for an alimentary epidemiology capable of looking at the entire process of social reproduction and the food system as well as the expressions of each in different ways of life, overcoming a purely individual and biologistic perspective. The article proposes that eating be studied as a total social fact within the school of thought of critical epidemiology, recognizing the existence of three different levels of reality - the general, particular and singular - as well as the existence of a margin of relative autonomy of subjects in the process of determination of food consumption and nutritional status. Read More

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September 2018
2 Reads

Characterization of first blastomeres in Patagonian blenny (Eleginops maclovinus) (Perciformes: Eleginopidae).

Zygote 2018 Dec 5:1-6. Epub 2018 Dec 5.

7Universidad de La Frontera,CEBIOR, Chile.

SummaryThere is no information about the characteristics of early cleavage in the Patagonian blennie (Eleginops maclovinus), which can be used as a diagnostic tool for embryo quality. The purpose of this investigation, therefore, was to characterize the first blastomeres of E. maclovinus morphologically. Read More

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December 2018
1 Read

Robot-assisted resection of gastric duplication cysts in a child: a detailed case report.

Pediatr Med Chir 2018 Dec 4;40(2). Epub 2018 Dec 4.

Department of Pediatric Surgery, "Spirito Santo" Hospital, Pescara; "G. d'Annunzio" University, Chieti-Pescara.

Gastric duplication cysts (GDCs) represent 4-9% of alimentary tract duplications. Early diagnosis and surgical excision are essential to avoid morbidity or neoplastic degeneration. Roboticassisted excision of GDCs has never been described in childhood. Read More

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December 2018
7 Reads

Pattern and Risk Factors of Congenital Anomaly in Newborn in a Tertiary Level Private Medical College Hospital, Bangladesh.

Mymensingh Med J 2018 Oct;27(4):805-812

Dr Mohosina Siddika, Associate Professor, Department of Gyeanocology & Obstetrics, Community Based Medical Colloge Bangladesh, Mymensingh, Bangladesh.

The cross sectional study was done to estimate the prevalence of various congenital malformations among the patients delivered in Community Based Medical College Hospital (CBMCH), Mymensingh, Bangladesh and corresponding risk factors were also studied from July 2014 to December 2015. A total of 2560 babies who were born at Community Based Medical College Hospital (CBMCH) were enrolled in this study. The newborn babies were examined and assessed for detection of congenital malformation, system wise distribution and risk factors attributable. Read More

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October 2018
1 Read

Parasitic Helminths in Wild Boars () in Mazandaran Province, Northern Iran.

Iran J Parasitol 2018 Jul-Sep;13(3):416-422

Toxoplasmosis Research Center, Mazandaran University of Medical Sciences, Sari, Iran.

Background: Wild boars () are distributed worldwide and found in many parts of Iran. Although is reservoirs for many parasites, there is little data on helminthic prevalence in them. We aimed to survey the status of helminthic infections in in the Mazandaran Province of northern Iran. Read More

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November 2018

Tracing individuals and populations of the tambaqui, Colossoma macropomum (Cuvier, 1818), from Brazilian hatcheries using microsatellites markers.

J Sci Food Agric 2018 Nov 26. Epub 2018 Nov 26.

Laboratory of Genetics and Molecular Biology, Institute of Coastal Studies, Federal University of Pará, Bragança, PA, Brazil.

Background: In recent years, tracing of alimentary produce of animal origin has become increasingly important, for economic, food safety, and ecological reasons. The tambaqui, Colossoma macropomum, is the native fish most farmed in Brazil. The reliable identification of the origin of tambaquis (wild or farmed) offered for sale to the general public has become necessary to satisfy regulatory norms and uphold consumer confidence. Read More

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November 2018

Residue Distribution and Depletion of Ractopamine in Goat Tissues After Exposure to Growth-Promoting Dose.

J Anal Toxicol 2018 Nov 22. Epub 2018 Nov 22.

Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, PR China.

The objectives of the present study was to investigated the ractopamine (RAC) distribution and depletion process in various tissues of goat including liver, kidney, spleen, lung, heart, fat, bile, brain and the eyes. The experiment was carried out on 21 goats (18 treated and 3 controls). Treated goats were orally administered RAC in a dose of 1 mg/kg body mass per day for last 28 days and randomly sacrificed on withdrawal days of 0. Read More

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November 2018
1 Read
2.627 Impact Factor

Dietary plant miRNAs as an augmented therapy: cross-kingdom gene regulation.

RNA Biol 2018 Nov 26. Epub 2018 Nov 26.

a CSIR-National Botanical Research Institute, Council of Scientific and Industrial Research (CSIR-NBRI) , Rana Pratap Marg, Lucknow - 226001 , India.

Cross-kingdom gene regulation by microRNAs (miRNAs) initiated a hot debate on the effective role of orally acquired plant miRNAs on human gene expression. It resulted in the expansion of gene regulation theories and role of plant miRNAs in cross-kingdom regulation of gene expression. This opened up the discussion that "Whether we really get what we eat?" and "Whether the orally acquired miRNAs really have a biologically important consequences after entering our digestive and circulatory system?" The reports of orally acquired plant miRNAs inside human alimentary canal have been a topic of discussion in the scientific community. Read More

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November 2018
1 Read

A long biliopancreatic and short alimentary limb results in more weight loss in revisional RYGB surgery. Outcomes of the randomized controlled ELEGANCE REDO trial.

Surg Obes Relat Dis 2018 Oct 18. Epub 2018 Oct 18.

Department of Surgery, Rijnstate Hospital, Arnhem, the Netherlands.

Background: For a number of years the laparoscopic adjustable gastric band has been one of the leading bariatric procedures with good short-term outcomes. However, inadequate weight loss, weight regain, and other band-related complications in the long term led to an increase in revisional Roux-en-Y gastric bypass (RYGB) procedures. Lengthening the biliopancreatic limb, a relatively simple and safe adjustment of the standard technique, could improve the results of the revisional procedure. Read More

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October 2018
3 Reads

Increased Risk of Ulcerative Colitis in Patients with Periodontal Disease: A Nationwide Population-Based Cohort Study.

Int J Environ Res Public Health 2018 Nov 21;15(11). Epub 2018 Nov 21.

Graduate Institute of Life Sciences, National Defense Medical Center, Taipei 114, Taiwan.

Both periodontal disease (PD) and inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), are important diseases of the alimentary tract. Microbiome and immune-mediated inflammatory processes play important roles in these diseases. An association between PD and IBD may exist. Read More

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November 2018
4 Reads

The impact of sarcopenia and myosteatosis on postoperative outcomes in patients with inflammatory bowel disease.

Eur Radiol Exp 2018 Nov 21;2(1):37. Epub 2018 Nov 21.

Department of Surgery, Cork University Hospital, Cork, Ireland.

Background: Inflammatory bowel disease (IBD) is a relatively common disorder with significant associated morbidity. Sarcopenia and myosteatosis are associated with adverse postoperative outcomes. This study investigated outcomes in IBD patients undergoing surgical resection relative to the presence of sarcopenia and myosteatosis. Read More

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November 2018
3 Reads

Compositional Dynamics of the Milk Fat Globule and Its Role in Infant Development.

Front Pediatr 2018 24;6:313. Epub 2018 Oct 24.

Department of Food Science and Technology, University of California, Davis, Davis, CA, United States.

Human milk is uniquely optimized for the needs of the developing infant. Its composition is complex and dynamic, driven primarily by maternal genetics, and to a lesser extent by diet and environment. One important component that is gaining attention is the milk fat globule (MFG). Read More

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October 2018
5 Reads

The impact of a nutritional intervention based on egg white for phosphorus control in hemodialyis patients.

Nutr Metab Cardiovasc Dis 2018 Sep 28. Epub 2018 Sep 28.

Department of Neuroscience, Reproductive Sciences and Dentistry, Division of Pharmacology, Federico II University of Naples, Italy; Federico II University Hospital, Naples, Italy.

Background And Aims: Here we describe a dietary intervention for hyperphosphatemia in dialysis patients based on the partial replacement of meat and fish, which are one of the main sources of alimentary phosphorous, with egg white, a virtually phosphorous-free protein source. This intervention aims to reduce phosphorous intake without causing protein wasting.

Patients And Methods: As many as 23 hyperphosphatemic patients (15 male and 8 female, mean age 53. Read More

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September 2018
3 Reads

Redo Gracilis Muscle Transposition for Recurrent Complex Pouch-Vaginal Fistula: A Feasible and Effective Pouch Salvage Surgical Procedure.

Am Surg 2017 Dec;83(12):e488-e489

Surgery of the Alimentary Tract, Sant'Orsola-Malpighi Hospital, Alma Mater Studiorum University of Bologna, Bologna, Italy.

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December 2017
4 Reads

Importance of ciliates as food for fish larvae in a shallow sea bay and a large shallow lake.

Eur J Protistol 2018 Nov 2;67:59-70. Epub 2018 Nov 2.

Centre for Limnology, Institute of Agricultural and Environmental Research, Estonian University of Life Sciences, Rannu 61117, Tartu, Estonia.

We estimated the consumption of planktonic ciliates by fish larvae in the Väinameri Sea (a shallow semi-enclosed bay of the Baltic Sea) and Lake Võrtsjärv (a shallow and eutrophic lake). Our primary hypothesis was that planktonic ciliates constitute a substantial component of the diet of fish larvae in both environments. We also assumed that the contribution of ciliates to larval nutrition is bigger in lacustrine than in marine environment because ciliates are usually more abundant in lakes. Read More

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November 2018
1 Read

Vitamin K status and inflammation are associated with cognition in older Irish adults.

Nutr Neurosci 2018 Nov 19:1-9. Epub 2018 Nov 19.

a Department of Biological Sciences , University of Limerick , Limerick , Ireland.

Studies have shown associations between reduced vitamin K status and poor cognitive function. However, despite this apparent link, direct studies measuring cognitive function, vitamin K status and inflammation are lacking. In the current study, The ELDERMET cohort was investigated to identify associations between cognition, vitamin K status and inflammation. Read More

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November 2018

Low-dose CT imaging of the acute abdomen using model-based iterative reconstruction: a prospective study.

Emerg Radiol 2018 Nov 17. Epub 2018 Nov 17.

Department of Radiology, Cork University Hospital, University College Cork, Cork, Ireland.

Objectives: Performance of a modified abdominopelvic CT protocol reconstructed using full iterative reconstruction (IR) was assessed for imaging patients presenting with acute abdominal symptoms.

Materials And Methods: Fifty-seven patients (17 male, 40 female; mean age of 56.5 ± 8 years) were prospectively studied. Read More

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November 2018
4 Reads

Fermenters in the Earthworm Gut: Do Transients Matter?

FEMS Microbiol Ecol 2018 Nov 16. Epub 2018 Nov 16.

Department of Ecological Microbiology, University of Bayreuth, 95440 Bayreuth, Germany.

Earthworms have profound impact on soil-based ecosystems. Although theoretical considerations suggest that most microbes in the earthworm gut are likely ingested and transient, the non-responsiveness of soil microbes to a specific high value gut nutrient and anoxia has made it difficult to demonstrate that responsive gut fermenters are derived from soil. Therefore, soil and gut content of the model earthworm Lumbricus terrestris were examined for their fermentative capabilities. Read More

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November 2018
4 Reads

Use of triggers tools to search for adverse drug reactions in the elderly admitted to emergency departments.

Cien Saude Colet 2018 Nov;23(11):3997-4006

Faculdade de Saúde Pública , USP . São Paulo SP Brasil .

Adverse drug reactions (ADRs) can cause illness, disability or death, especially in the elderly. An active search for suspected ADRs was carried out using triggers, which motivated the search of elderly people under care in adult emergency departments (ED). It was a cross-sectional and retrospective study that used an adaptation of the Institute of Health Care Improvement triggers. Read More

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November 2018
1 Read

Characteristics and Outcomes of 79 Patients with an Insulinoma: A Nationwide Retrospective Study in Finland.

Int J Endocrinol 2018 23;2018:2059481. Epub 2018 Oct 23.

Faculty of Medicine and Life Sciences, University of Tampere, Finland.

Objective: Insulinomas are rare pancreatic tumours. Population-based data on their incidence, clinical picture, diagnosis, and treatment are almost nonexistent. The aim of this study was to clarify these aspects in a nationwide cohort of insulinoma patients diagnosed during three decades. Read More

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October 2018
5 Reads

Biodegradable biliary stents preferable to plastic stent therapy in post-cholecystectomy bile leak and avoid second endoscopy.

Scand J Gastroenterol 2018 Nov 5:1-5. Epub 2018 Nov 5.

a Department of Gastroenterology and Alimentary Tract Surgery , Tampere University Hospital , Tampere , Finland.

Background: The treatment of post-cholecystectomy bile leak is endoscopic retrograde cholangiography (ERC) with plastic stent (PS) insertion combined with external drainage. Self-expanding biodegradable biliary stents (BDBS) have only recently become available.

Aim: The aim was to compare success rate, adverse events and costs of BDBS with PS in the treatment of post-cholecystectomy cystic duct leak Materials and methods: Patients recruited prospectively for treatment with BDBS during the period 2014-2017 were compared to a control group treated with PS in a non-randomized setting. Read More

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November 2018
5 Reads

Surface CD200 and CD200R antigens on lymphocytes in advanced gastric cancer: a new potential target for immunotherapy.

Arch Med Sci 2018 Oct 21;14(6):1271-1280. Epub 2018 May 21.

Department of Clinical Immunology and Immunotherapy, Medical University of Lublin, Lublin, Poland.

Introduction: Gastric cancer (GC) is one of the leading causes of cancer death worldwide. The membrane glycoprotein CD200, widely expressed on multiple cells/tissues, uses a structurally similar receptor (CD200R), delivering immunoregulatory signals. There is evidence that CD200/CD200R signaling suppresses anti-tumor responses in different types of malignancies. Read More

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October 2018
5 Reads

In Reply to the Invitation from the Editor to the Letter "What Is the Current Evidence to Define the Length of the Alimentary Limb in the Laparoscopic Gastric Bypass Technique?"

Obes Surg 2018 Nov 3. Epub 2018 Nov 3.

Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, No. 17, Yongwaizheng Road, Donghu District, Nanchang, 330006, Jiangxi Province, China.

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November 2018

What Is the Current Evidence to Define the Length of the Alimentary Limb in the Laparoscopic Gastric Bypass Technique?

Obes Surg 2018 Nov 3. Epub 2018 Nov 3.

Department of Surgery, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga No 15, Sección XVI, Tlalpan, 14080, Mexico City, Mexico.

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November 2018
2 Reads

Bergamot Polyphenols Boost Therapeutic Effects of the Diet on Non-Alcoholic Steatohepatitis (NASH) Induced by "Junk Food": Evidence for Anti-Inflammatory Activity.

Nutrients 2018 Nov 1;10(11). Epub 2018 Nov 1.

Department of Health Sciences, Magna Graecia University, Campus Germaneto, 88100 Catanzaro, Italy.

Wrong alimentary behaviors and so-called "junk food" are a driving force for the rising incidence of non-alcoholic fatty liver disease (NAFLD) among children and adults. The "junk food" toxicity can be studied in "cafeteria" (CAF) diet animal model. Young rats exposed to CAF diet become obese and rapidly develop NAFLD. Read More

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November 2018
4 Reads

A huge completely isolated duplication cyst complicated by torsion and lined by 3 different mucosal epithelial components in an adult: A case report.

Medicine (Baltimore) 2018 Nov;97(44):e13005

Rationale: Intestinal or enteric duplication (ED) does exit as a rare congenital malformation of the gastrointestinal system clinically. It is a separate entity, but can be communicated with the gastrointestinal tract. It is characterized by a well-developed muscular wall and lumen endowed with ectopic mucosa, simulating a portion of normal bowel. Read More

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November 2018
5 Reads

Feeding influence on the oxidative stability of poultry meat treated with ozone.

Asian-Australas J Anim Sci 2018 Oct 26. Epub 2018 Oct 26.

Faculty of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, 64100 Teramo, Italy.

Objective: Ozone is considered a strong antimicrobial agent with numerous potential applications in alimentary industry. However, its high oxidizing potential can induce alterations in foods by acting in particular on the unsaturated fatty acids. The aim of this study was to investigate the effect of ozonation on the oxidative stability of chicken breast meat obtained from animals subjected to different feeding strategies. Read More

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October 2018
2 Reads

Copper Metabolism of Newborns Is Adapted to Milk Ceruloplasmin as a Nutritive Source of Copper: Overview of the Current Data.

Nutrients 2018 Oct 30;10(11). Epub 2018 Oct 30.

Department of Physiology and Pharmacology, Des Moines University, Des Moines, IA 50312, USA.

Copper, which can potentially be a highly toxic agent, is an essential nutrient due to its role as a cofactor for cuproenzymes and its participation in signaling pathways. In mammals, the liver is a central organ that controls copper turnover throughout the body, including copper absorption, distribution, and excretion. In ontogenesis, there are two types of copper metabolism, embryonic and adult, which maintain the balance of copper in each of these periods of life, respectively. Read More

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October 2018
1 Read

[Synchronous gastrointestinal stromal tumor of stomach and invasive ductal carcinoma of both breasts].

Pol Merkur Lekarski 2018 Oct;45(268):161-163

Department of Oncologic Surgery, Medical University of Gdańsk, Poland.

Gastrointestinal stromal tumor (GIST), despite the fact that it accounts for less than 5% of all sarcomas, is the most common mesenchymal tumor of the alimentary canal. Synchronous and metachronous stromal tumors are very rare findings. Only a few such cases can be found in the literature, and yet most of them is connected with Von Recklinghausen's disease or Carney's triad in which it is proved a much higher frequency of occurrence of this kind of tumors. Read More

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October 2018
2 Reads

Histochemistry in the diagnosis of non-neoplastic gastrointestinal disorders.

Semin Diagn Pathol 2018 Nov 16;35(6):370-380. Epub 2018 Oct 16.

Department of Pathology, St. Jude Medical Center, Fullerton, CA 92835, United States. Electronic address:

The alimentary tract serves as host to a large number of diseases. In the non-neoplastic group of disorders, conventional histochemistry continues to play an important diagnostic role. It is particularly important in recognizing specific infectious diseases, such as Helicobacter gastritis, Whipple disease, intestinal tuberculosis and other forms of mycobacteriosis, malakoplakia, intestinal spirochetosis, fungal enteritides, amebiasis, cryptosporidiosis, isosporiasis, and microsporidiosis. Read More

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November 2018
6 Reads

A feasibility study of high-dose hypofractionated carbon ion radiation therapy using four fractions for localized hepatocellular carcinoma measuring 3 cm or larger.

Radiother Oncol 2018 Oct 23. Epub 2018 Oct 23.

Gunma University Heavy Ion Medical Center, Maebashi, Japan; Department of Radiation Oncology, Gunma University Hospital, Maebashi, Japan.

Background And Purpose: To evaluate the safety of carbon-ion radiotherapy (C-ion RT) using 60 Gy (relative biological effectiveness, RBE) in four fractions for patients with hepatocellular carcinoma (HCC).

Materials And Methods: The primary outcome was acute toxicities within 90 days. The secondary outcomes were late toxicities, local control, and progression-free survival and overall survival rates. Read More

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October 2018
6 Reads

Detection of Species and Associated Okadaic Acid in Farmed Shellfish: a Two-year Study from The Western Mediterranean Area.

J Vet Res 2018 Jun 24;62(2):137-144. Epub 2018 Oct 24.

Veterinary Public Health Institute of Sardinia, 07100 Sassari, Italy.

Introduction: Diarrhoetic shellfish poisoning (DSP), an alimentary intoxication known to lead to intestinal symptoms, and caused by toxins produced by some dinoflagellates (including several ), represents a serious threat to public health. The aim of this paper was to provide information about the occurrence and abundance of potentially toxic harmful algal species causing DSP, and the associated concentration of okadaic acid (OA) toxins. The departing assumption was that in the study area there was an increase in the presence both of species and OA and its derivates that could result in a risk to the health of seafood consumers. Read More

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June 2018
1 Read

Relationship Between Sitting Time, Physical Activity, and Metabolic Syndrome Among Adults Depending on Body Mass Index (BMI).

Med Sci Monit 2018 Oct 26;24:7633-7645. Epub 2018 Oct 26.

Department of Surgery and Surgical Nursing with The Scientific Research Laboratory, Institute of Medical Sciences, Faculty of Medicine and Health Sciences, Jan Kochanowski University, Kielce, Poland.

BACKGROUND The aim of this study was to assess the possible relationship between sitting time and physical activity and the risk of occurrence of metabolic syndrome and its components. Analyses were conducted in the whole sample, and with stratification according to BMI. We have formulated a hypothesis that individuals with different BMIs have different responses to metabolic health modifiers such as physical activity and sitting time. Read More

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October 2018
5 Reads

Long-term functional outcome after restorative proctocolectomy: a cross-sectional study.

Scand J Gastroenterol 2018 Oct 22:1-5. Epub 2018 Oct 22.

c School of Medicine , University of Tampere , Tampere , Finland.

Objective: Restorative proctocolectomy is the procedure of choice in the surgical treatment of ulcerative colitis. Functional outcome is the key result of surgery. The aim of this study was to evaluate the long term-functional outcome after the procedure. Read More

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October 2018
3 Reads

Trends of incidence and survival in patients with gastrointestinal mucinous adenocarcinoma.

Oncol Lett 2018 Nov 4;16(5):5791-5798. Epub 2018 Sep 4.

Department of General Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China.

The epidemiology and clinical outcome of gastrointestinal mucinous adenocarcinoma (MA) are not well illustrated. The present study aimed to explore the evolving epidemiology and prognostic factors that affect the survival of patients with MA in the gastrointestinal tract. A retrospective and population-based study was conducted to determine the annual age-adjusted incidence, overall survival (OS) and survival trend of gastrointestinal mucinous MA using nationally representative data from the Surveillance, Epidemiology, and End Results (SEER) program between 2000 and 2014. Read More

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November 2018
5 Reads

Development and testing of a new tick-borne encephalitis virus vaccine candidate for veterinary use.

Vaccine 2018 Nov 15;36(48):7257-7261. Epub 2018 Oct 15.

Department of Virology, Veterinary Research Institute, Brno, Czech Republic; Institute of Parasitology, Biology Centre of the Czech Academy of Sciences, Ceske Budejovice, Czech Republic. Electronic address:

In tick-borne encephalitis (TBE) endemic areas, consumption of unpasteurized milk or milk products from grazing domestic ruminants (goats, cattle, and sheep) represents a risk of TBE virus (TBEV) infection for humans. In addition to vaccination of humans, human alimentary TBEV infections can be avoided by pasteurizing milk or by vaccination of the ruminants. However, there is presently no TBEV vaccine for veterinary use. Read More

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November 2018
1 Read

Physical activity in relation to irritable bowel syndrome among Iranian adults.

PLoS One 2018 18;13(10):e0205806. Epub 2018 Oct 18.

Integrative Functional Gastroenterology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: Irritable bowel syndrome (IBS) is the most prevalent functional gastrointestinal disorder worldwide. Physical activity in relation to IBS has been investigated in few studies and data in this regard are conflicting.

Aim: To investigate the association between physical activity and IBS in a large sample of Iranian adults. Read More

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October 2018
7 Reads

Cross-Sectional Inverse Association of Regular Soy Intake with Insulin Resistance in Japanese Elderly.

J Nutr Gerontol Geriatr 2018 Oct 15:1-10. Epub 2018 Oct 15.

c Department of Health Management, School of Health Studies, Tokai University , Kanagawa , Japan.

Levels of isoflavones, biomarkers of soy intake, in 24-hour urine (24U) were inversely related to coronary heart disease (CHD) mortality in the World Health Organization's Cardiovascular Disease and Alimentary Comparison Study. Considering 24 U isoflavone levels were highest and CHD mortality was lowest in the Japanese, who maintained the world's longest life expectancy, the association of regular soy intake with cardiometabolic risk was investigated in Japanese adults (20-49 years old) and elderly (50-79 years old). In multivariate analysis adjusted for age, sex, and drug treatments, mean 24 U isoflavone excretion was significantly inversely associated with insulin resistance in the elderly and significantly associated with blood folate and potassium in the elderly, but also positively associated with 24 U salt in the elderly. Read More

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October 2018
3 Reads

Retraction: Randomised clinical trial: The clinical efficacy and safety of an alginate-antacid (Gaviscon Double Action) versus placebo, for decreasing upper gastrointestinal symptoms in symptomatic gastroesophageal reflux disease (GERD) in China by J. Sun, C. Yang, H. Zhao, P. Zheng, J. Wilkinson, B. Ng, Y. Yuan. Aliment Pharmacol Ther. 2015;42:845-854.

Authors:

Aliment Pharmacol Ther 2018 Nov;48(9):1039

The above article from Alimentary Pharmacology & Therapeutics, published online on 31 July 2015 on Wiley Online Library (wileyonlinelibrary.com), and in Volume 42, pp. 845-854, has been retracted by agreement between the authors, J. Read More

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November 2018

Feline low-grade alimentary lymphoma: an emerging entity and a potential animal model for human disease.

BMC Vet Res 2018 Oct 11;14(1):306. Epub 2018 Oct 11.

Internal Medicine Department, Université Paris-Est, École Nationale Vétérinaire d'Alfort, 7 Avenue du Général de Gaulle, 94700, Maisons-Alfort, France.

Background: Low-grade alimentary lymphoma (LGAL) is characterised by the infiltration of neoplastic T-lymphocytes, typically in the small intestine. The incidence of LGAL has increased over the last ten years and it is now the most frequent digestive neoplasia in cats and comprises 60 to 75% of gastrointestinal lymphoma cases. Given that LGAL shares common clinical, paraclinical and ultrasonographic features with inflammatory bowel diseases, establishing a diagnosis is challenging. Read More

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October 2018
5 Reads

Endoscopic removal of an impacted wooden toothpick in the wall of the sigmoid colon.

Wideochir Inne Tech Maloinwazyjne 2018 Sep 21;13(3):417-419. Epub 2018 May 21.

2 Department of General, Gastrointestinal Surgery and Surgical Oncology of the Alimentary Tract, Medical University of Lublin, Lublin, Poland.

Most ingested foreign bodies usually pass through the gastrointestinal tract without any complications. Sharp foreign bodies such as a wooden toothpick may cause severe complications, leading to an acute abdomen. They may also cause mild, non-specific gastrointestinal symptoms without significant findings. Read More

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September 2018
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Extended mutualism between termites and gut microbes: nutritional symbionts contribute to nest hygiene.

Naturwissenschaften 2018 Aug 30;105(9-10):52. Epub 2018 Aug 30.

Laboratory of Insect Ecology, Graduate School of Agriculture, Kyoto University, Kitashirakawa Oiwake-cho, Sakyo-ku, Kyoto, 606-8502, Japan.

All higher eukaryotes have established symbiotic relationships with diverse microorganisms. One of the most well-characterized symbiotic systems is that of termites and their intestinal microorganisms, which digest cellulose. Recently, diverse types of symbioses between gut microbes and host organisms including humans have received growing attention for various features of their complex interactions beyond nutrition. Read More

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August 2018
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