6,807 results match your criteria Alcohol and Substance Abuse Evaluation


Factors predicting satisfaction in outpatient substance abuse treatment: a prospective follow-up study.

Subst Abuse Treat Prev Policy 2020 May 24;15(1):35. Epub 2020 May 24.

The Finnish Foundation for Alcohol Studies, c/o THL, PL 30, 00271, Helsinki, Finland.

Background: While treatment satisfaction has been associated with better outcomes in substance abuse treatment, there is an obvious need for a more profound understanding of what predicts client's satisfaction with treatment. This study elucidates factors relevant to treatment outcome measured at follow-up in terms of satisfaction with the treatment received.

Methods: The research was implemented as a multisite study in outpatient clinics (N = 7) in southern and western Finland. Read More

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http://dx.doi.org/10.1186/s13011-020-00275-5DOI Listing

Gaps and challenges: WHO treatment recommendations for tobacco cessation and management of substance use disorders in people with severe mental illness.

BMC Psychiatry 2020 May 14;20(1):237. Epub 2020 May 14.

Centre for Global Mental Health, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.

Background: People with severe mental disorders (SMD) experience premature mortality mostly from preventable physical causes. The World Health Organization (WHO) have recently produced guidelines on the management of physical health conditions in SMD. This paper presents the evidence which led to the recommendations for tobacco cessation and management of substance use disorders in SMD. Read More

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http://dx.doi.org/10.1186/s12888-020-02623-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227317PMC

An Efficacy Trial of the Ho'ouna Pono Drug Prevention Curriculum: An Evaluation of a Culturally Grounded Substance Abuse Prevention Program in Rural Hawai'i.

Asian Am J Psychol 2019 Sep;10(3):239-248

University of Hawai'i at Mānoa.

This study reports on the drug use outcomes in an efficacy trial of a culturally grounded, school-based, substance abuse prevention curriculum in rural Hawai'i. The curriculum (Ho'ouna Pono) was developed through a series of pre-prevention and pilot/feasibility studies funded by the National Institute on Drug Abuse, and focuses on culturally relevant drug resistance skills training. The present study used a dynamic wait-listed control group design (Brown, Wyman, Guo, & Pena, 2006), in which cohorts of middle/intermediate public schools on Hawai'i Island were exposed to the curriculum at different time periods over a two-year time frame. Read More

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http://dx.doi.org/10.1037/aap0000164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213509PMC
September 2019

The Impact of Obesity on Sexual Functions and Dyadic Consensus in Patients with Obesity.

Metab Syndr Relat Disord 2020 May 11. Epub 2020 May 11.

Department of Internal Medicine Clinic, University of Health Sciences, Istanbul Training and Research Hospital, İstanbul, Turkey.

Obesity is a chronic disease with several co-morbidities that increase morbidity and mortality and decrease quality of life. Psychopathologies are an important group of co-morbidities. In this study, it was aimed to search for the presence of depression and sexual dysfunction in patients with obesity, examine impact of obesity on marital adjustment, and highlight those important problems that are usually overlooked. Read More

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http://dx.doi.org/10.1089/met.2020.0012DOI Listing

Clinical correlates of paliperidone palmitate and aripiprazole monohydrate prescription for subjects with schizophrenia-spectrum disorders: findings from the STAR Network Depot Study.

Int Clin Psychopharmacol 2020 May 3. Epub 2020 May 3.

Department of Medicine and Surgery, University of Milano Bicocca, Monza.

This study, based on the 'Servizi Territoriali Associati per la Ricerca' (STAR) Network Depot Study nationwide baseline data, explored whether individual symptoms severity and clusters might influence the prescription of paliperidone palmitate 1-month (PP1M) vs. aripiprazole monohydrate. The Brief Psychiatric Rating Scale (BPRS) was used to assess psychopathology and relevant symptoms clusters. Read More

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http://dx.doi.org/10.1097/YIC.0000000000000317DOI Listing

Brain-derived neurotrophic factor and glutathione peroxidase as state biomarkers in alcohol use disorder patients undergoing detoxification.

Medicine (Baltimore) 2020 Apr;99(17):e19938

Department of Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.

The pathophysiology of alcohol use disorder (AUD) is not totally clear. The aim of this study was to investigate the serum levels of brain-derived neurotrophic factor (BDNF) and oxidative stress markers in AUD patients during alcohol detoxification. Evaluation of changes in BDNF, glutathione peroxidase (GPX), catalase, superoxide dismutase, thiobarbituric acid reactive substances, 8-hydroxy 2'-deoxyguanosine, PCC and S100B were carried out. Read More

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http://dx.doi.org/10.1097/MD.0000000000019938DOI Listing

Global injury morbidity and mortality from 1990 to 2017: results from the Global Burden of Disease Study 2017.

Authors:
Spencer L James Chris D Castle Zachary V Dingels Jack T Fox Erin B Hamilton Zichen Liu Nicholas L S Roberts Dillon O Sylte Nathaniel J Henry Kate E LeGrand Ahmed Abdelalim Amir Abdoli Ibrahim Abdollahpour Rizwan Suliankatchi Abdulkader Aidin Abedi Akine Eshete Abosetugn Abdelrahman I Abushouk Oladimeji M Adebayo Marcela Agudelo-Botero Tauseef Ahmad Rushdia Ahmed Muktar Beshir Ahmed Miloud Taki Eddine Aichour Fares Alahdab Genet Melak Alamene Fahad Mashhour Alanezi Animut Alebel Niguse Meles Alema Suliman A Alghnam Samar Al-Hajj Beriwan Abdulqadir Ali Saqib Ali Mahtab Alikhani Cyrus Alinia Vahid Alipour Syed Mohamed Aljunid Amir Almasi-Hashiani Nihad A Almasri Khalid Altirkawi Yasser Sami Abdeldayem Amer Saeed Amini Arianna Maever Loreche Amit Catalina Liliana Andrei Alireza Ansari-Moghaddam Carl Abelardo T Antonio Seth Christopher Yaw Appiah Jalal Arabloo Morteza Arab-Zozani Zohreh Arefi Olatunde Aremu Filippo Ariani Amit Arora Malke Asaad Babak Asghari Nefsu Awoke Beatriz Paulina Ayala Quintanilla Getinet Ayano Martin Amogre Ayanore Samad Azari Ghasem Azarian Alaa Badawi Ashish D Badiye Eleni Bagli Atif Amin Baig Mohan Bairwa Ahad Bakhtiari Arun Balachandran Maciej Banach Srikanta K Banerjee Palash Chandra Banik Amrit Banstola Suzanne Lyn Barker-Collo Till Winfried Bärnighausen Lope H Barrero Akbar Barzegar Mohsen Bayati Bayisa Abdissa Baye Neeraj Bedi Masoud Behzadifar Tariku Tesfaye Bekuma Habte Belete Corina Benjet Derrick A Bennett Isabela M Bensenor Kidanemaryam Berhe Pankaj Bhardwaj Anusha Ganapati Bhat Krittika Bhattacharyya Sadia Bibi Ali Bijani Muhammad Shahdaat Bin Sayeed Guilherme Borges Antonio Maria Borzì Soufiane Boufous Alexandra Brazinova Nikolay Ivanovich Briko Shyam S Budhathoki Josip Car Rosario Cárdenas Félix Carvalho João Mauricio Castaldelli-Maia Carlos A Castañeda-Orjuela Giulio Castelpietra Ferrán Catalá-López Ester Cerin Joht S Chandan Wagaye Fentahun Chanie Soosanna Kumary Chattu Vijay Kumar Chattu Irini Chatziralli Neha Chaudhary Daniel Youngwhan Cho Mohiuddin Ahsanul Kabir Chowdhury Dinh-Toi Chu Samantha M Colquhoun Maria-Magdalena Constantin Vera M Costa Giovanni Damiani Ahmad Daryani Claudio Alberto Dávila-Cervantes Feleke Mekonnen Demeke Asmamaw Bizuneh Demis Gebre Teklemariam Demoz Desalegn Getnet Demsie Afshin Derakhshani Kebede Deribe Rupak Desai Mostafa Dianati Nasab Diana Dias da Silva Zahra Sadat Dibaji Forooshani Kerrie E Doyle Tim Robert Driscoll Eleonora Dubljanin Bereket Duko Adema Arielle Wilder Eagan Aziz Eftekhari Elham Ehsani-Chimeh Maysaa El Sayed Zaki Demelash Abewa Elemineh Shaimaa I El-Jaafary Ziad El-Khatib Christian Lycke Ellingsen Mohammad Hassan Emamian Daniel Adane Endalew Sharareh Eskandarieh Pawan Sirwan Faris Andre Faro Farshad Farzadfar Yousef Fatahi Wubalem Fekadu Tomas Y Ferede Seyed-Mohammad Fereshtehnejad Eduarda Fernandes Pietro Ferrara Garumma Tolu Feyissa Irina Filip Florian Fischer Morenike Oluwatoyin Folayan Masoud Foroutan Joel Msafiri Francis Richard Charles Franklin Takeshi Fukumoto Biniyam Sahiledengle Geberemariyam Abadi Kahsu Gebre Ketema Bizuwork Gebremedhin Gebreamlak Gebremedhn Gebremeskel Berhe Gebremichael Getnet Azeze Gedefaw Birhanu Geta Mansour Ghafourifard Farhad Ghamari Ahmad Ghashghaee Asadollah Gholamian Tiffany K Gill Alessandra C Goulart Ayman Grada Michal Grivna Mohammed Ibrahim Mohialdeen Gubari Rafael Alves Guimarães Yuming Guo Gaurav Gupta Juanita A Haagsma Nima Hafezi-Nejad Hassan Haghparast Bidgoli Brian James Hall Randah R Hamadeh Samer Hamidi Josep Maria Haro Md Mehedi Hasan Amir Hasanzadeh Soheil Hassanipour Hadi Hassankhani Hamid Yimam Hassen Rasmus Havmoeller Khezar Hayat Delia Hendrie Fatemeh Heydarpour Martha Híjar Hung Chak Ho Chi Linh Hoang Michael K Hole Ramesh Holla Naznin Hossain Mehdi Hosseinzadeh Sorin Hostiuc Guoqing Hu Segun Emmanuel Ibitoye Olayinka Stephen Ilesanmi Irena Ilic Milena D Ilic Leeberk Raja Inbaraj Endang Indriasih Seyed Sina Naghibi Irvani Sheikh Mohammed Shariful Islam M Mofizul Islam Rebecca Q Ivers Kathryn H Jacobsen Mohammad Ali Jahani Nader Jahanmehr Mihajlo Jakovljevic Farzad Jalilian Sudha Jayaraman Achala Upendra Jayatilleke Ravi Prakash Jha Yetunde O John-Akinola Jost B Jonas Nitin Joseph Farahnaz Joukar Jacek Jerzy Jozwiak Suresh Banayya Jungari Mikk Jürisson Ali Kabir Rajendra Kadel Amaha Kahsay Leila R Kalankesh Rohollah Kalhor Teshome Abegaz Kamil Tanuj Kanchan Neeti Kapoor Manoochehr Karami Amir Kasaeian Hagazi Gebremedhin Kassaye Taras Kavetskyy Hafte Kahsay Kebede Peter Njenga Keiyoro Abraham Getachew Kelbore Bayew Kelkay Yousef Saleh Khader Morteza Abdullatif Khafaie Nauman Khalid Ibrahim A Khalil Rovshan Khalilov Mohammad Khammarnia Ejaz Ahmad Khan Maseer Khan Tripti Khanna Habibolah Khazaie Fatemeh Khosravi Shadmani Roba Khundkar Daniel N Kiirithio Young-Eun Kim Daniel Kim Yun Jin Kim Adnan Kisa Sezer Kisa Hamidreza Komaki Shivakumar K M Kondlahalli Vladimir Andreevich Korshunov Ai Koyanagi Moritz U G Kraemer Kewal Krishan Burcu Kucuk Bicer Nuworza Kugbey Vivek Kumar Nithin Kumar G Anil Kumar Manasi Kumar Girikumar Kumaresh Om P Kurmi Oluwatosin Kuti Carlo La Vecchia Faris Hasan Lami Prabhat Lamichhane Justin J Lang Van C Lansingh Dennis Odai Laryea Savita Lasrado Arman Latifi Paolo Lauriola Janet L Leasher Shaun Wen Huey Lee Tsegaye Lolaso Lenjebo Miriam Levi Shanshan Li Shai Linn Xuefeng Liu Alan D Lopez Paulo A Lotufo Raimundas Lunevicius Ronan A Lyons Mohammed Madadin Muhammed Magdy Abd El Razek Narayan Bahadur Mahotra Marek Majdan Azeem Majeed Jeadran N Malagon-Rojas Venkatesh Maled Reza Malekzadeh Deborah Carvalho Malta Navid Manafi Amir Manafi Ana-Laura Manda Narayana Manjunatha Fariborz Mansour-Ghanaei Borhan Mansouri Mohammad Ali Mansournia Joemer C Maravilla Lyn M March Amanda J Mason-Jones Seyedeh Zahra Masoumi Benjamin Ballard Massenburg Pallab K Maulik Gebrekiros Gebremichael Meles Addisu Melese Zeleke Aschalew Melketsedik Peter T N Memiah Walter Mendoza Ritesh G Menezes Meresa Berwo Mengesha Melkamu Merid Mengesha Tuomo J Meretoja Atte Meretoja Hayimro Edemealem Merie Tomislav Mestrovic Bartosz Miazgowski Tomasz Miazgowski Ted R Miller G K Mini Andreea Mirica Erkin M Mirrakhimov Mehdi Mirzaei-Alavijeh Prasanna Mithra Babak Moazen Masoud Moghadaszadeh Efat Mohamadi Yousef Mohammad Karzan Abdulmuhsin Mohammad Aso Mohammad Darwesh Naser Mohammad Gholi Mezerji Abdollah Mohammadian-Hafshejani Milad Mohammadoo-Khorasani Reza Mohammadpourhodki Shafiu Mohammed Jemal Abdu Mohammed Farnam Mohebi Mariam Molokhia Lorenzo Monasta Yoshan Moodley Mahmood Moosazadeh Masoud Moradi Ghobad Moradi Maziar Moradi-Lakeh Farhad Moradpour Lidia Morawska Ilais Moreno Velásquez Naho Morisaki Shane Douglas Morrison Tilahun Belete Mossie Atalay Goshu Muluneh Srinivas Murthy Kamarul Imran Musa Ghulam Mustafa Ashraf F Nabhan Ahamarshan Jayaraman Nagarajan Gurudatta Naik Mukhammad David Naimzada Farid Najafi Vinay Nangia Bruno Ramos Nascimento Morteza Naserbakht Vinod Nayak Duduzile Edith Ndwandwe Ionut Negoi Josephine W Ngunjiri Cuong Tat Nguyen Huong Lan Thi Nguyen Rajan Nikbakhsh Dina Nur Anggraini Ningrum Chukwudi A Nnaji Peter S Nyasulu Felix Akpojene Ogbo Onome Bright Oghenetega In-Hwan Oh Emmanuel Wandera Okunga Andrew T Olagunju Tinuke O Olagunju Ahmed Omar Bali Obinna E Onwujekwe Kwaku Oppong Asante Heather M Orpana Erika Ota Nikita Otstavnov Stanislav S Otstavnov Mahesh P A Jagadish Rao Padubidri Smita Pakhale Keyvan Pakshir Songhomitra Panda-Jonas Eun-Kee Park Sangram Kishor Patel Ashish Pathak Sanghamitra Pati George C Patton Kebreab Paulos Amy E Peden Veincent Christian Filipino Pepito Jeevan Pereira Hai Quang Pham Michael R Phillips Marina Pinheiro Roman V Polibin Suzanne Polinder Hossein Poustchi Swayam Prakash Dimas Ria Angga Pribadi Parul Puri Zahiruddin Quazi Syed Mohammad Rabiee Navid Rabiee Amir Radfar Anwar Rafay Ata Rafiee Alireza Rafiei Fakher Rahim Siavash Rahimi Vafa Rahimi-Movaghar Muhammad Aziz Rahman Ali Rajabpour-Sanati Fatemeh Rajati Ivo Rakovac Kavitha Ranganathan Sowmya J Rao 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Dora Sigfusdottir Pankaj Kumar Singh Jasvinder A Singh Dhirendra Narain Sinha Catalin-Gabriel Smarandache Emma U R Smith Amin Soheili Bija Soleymani Ali Reza Soltanian Joan B Soriano Muluken Bekele Sorrie Ireneous N Soyiri Dan J Stein Mark A Stokes Mu'awiyyah Babale Sufiyan Hafiz Ansar Rasul Suleria Bryan L Sykes Rafael Tabarés-Seisdedos Karen M Tabb Biruk Wogayehu Taddele Degena Bahrey Tadesse Animut Tagele Tamiru Ingan Ukur Tarigan Yonatal Mesfin Tefera Arash Tehrani-Banihashemi Merhawi Gebremedhin Tekle Gebretsadkan Hintsa Tekulu Ayenew Kassie Tesema Berhe Etsay Tesfay Rekha Thapar Asres Bedaso Tilahune Kenean Getaneh Tlaye Hamid Reza Tohidinik Roman Topor-Madry Bach Xuan Tran Khanh Bao Tran Jaya Prasad Tripathy Alexander C Tsai Lorainne Tudor Car Saif Ullah Irfan Ullah Maida Umar Bhaskaran Unnikrishnan Era Upadhyay Olalekan A Uthman Pascual R Valdez Tommi Juhani Vasankari Narayanaswamy Venketasubramanian Francesco S Violante Vasily Vlassov Yasir Waheed Girmay Teklay Weldesamuel Andrea Werdecker Taweewat Wiangkham Haileab Fekadu Wolde Dawit Habte Woldeyes Dawit Zewdu Wondafrash Temesgen Gebeyehu Wondmeneh Adam Belay Wondmieneh Ai-Min Wu Rajaram Yadav Ali Yadollahpour Yuichiro Yano Sanni Yaya Vahid Yazdi-Feyzabadi Paul Yip Engida Yisma Naohiro Yonemoto Seok-Jun Yoon Yoosik Youm Mustafa Z Younis Zabihollah Yousefi Yong Yu Chuanhua Yu Hasan Yusefzadeh Telma Zahirian Moghadam Zoubida Zaidi Sojib Bin Zaman Mohammad Zamani Maryam Zamanian Hamed Zandian Ahmad Zarei Fatemeh Zare Zhi-Jiang Zhang Yunquan Zhang Sanjay Zodpey Lalit Dandona Rakhi Dandona Louisa Degenhardt Samath Dhamminda Dharmaratne Simon I Hay Ali H Mokdad Robert C Reiner Benn Sartorius Theo Vos

Inj Prev 2020 Apr 24. Epub 2020 Apr 24.

Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.

Background: Past research in population health trends has shown that injuries form a substantial burden of population health loss. Regular updates to injury burden assessments are critical. We report Global Burden of Disease (GBD) 2017 Study estimates on morbidity and mortality for all injuries. Read More

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http://dx.doi.org/10.1136/injuryprev-2019-043494DOI Listing
April 2020
1.941 Impact Factor

Comorbidities in an Australian sample of chronic and new opioid users.

J Opioid Manag 2020 Mar/Apr;16(2):103-110

Director, Quality Use of Medicines and Pharmacy Research Centre, Sansom Institute for Health Research, School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, Australia.

Introduction And Aims: Mental health disorders and substance abuse are risk factors that both precede and follow chronic opioid use. We predicted that incident opioid users would have lower rates of mental health comorbidities than chronic opioid users, but that incident chronic opioid users would have lower rates of mental health comorbidities than prevalent chronic users.

Design And Methods: We used administrative health claims data to evaluate differences in lifetime mental health and substance abuse comorbidity profiles of people who were prevalent and incident chronic opioid users, as well as those who used opioids acutely. Read More

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http://dx.doi.org/10.5055/jom.2020.0556DOI Listing

Looking back, moving forward: 50 years of South African Medical Research Council alcohol-related publications.

S Afr Med J 2019 Dec 5;109(11b):30-35. Epub 2019 Dec 5.

Alcohol, Tobacco and Other Drug Research Unit, South African Medical Research Council, Cape Town, South Africa; Department of Psychiatry, Faculty of Medicine and Health Sciences, Stellenbosch University and Tygerberg Hospital, South Africa.

Background: Alcohol is one of the highest risk factors for death and disability in South Africa (SA). Objective. To explore the trajectory of empirical research on alcohol in SA between 1969 and 2019, with an emphasis on South African Medical Research Council (SAMRC) authored publications. Read More

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http://dx.doi.org/10.7196/SAMJ.2019.v109i11b.14277DOI Listing
December 2019

[Medical management of alcohol use disorders].

Authors:
François Paille

Rev Prat 2019 Oct;69(8):909-916

Département d'addictologie Centre psychothérapique de Laxou, Laxou, France.

Medical management of alcohol use disorders. Psychosocial support remains the key element of treatment of patients with an alcohol use disorder in order to either decrease or cease their alcohol consumption. However two drugs can now be used to reduce alcohol consumption: nalmefene and baclofen. Read More

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October 2019

Psychometric evaluation of the Substance Abuse Subtle Screening Inventory-3 with Northern Plains American Indians.

Psychol Serv 2020 Mar 23. Epub 2020 Mar 23.

Department of Counseling and Community Services, University of North Dakota.

The efficacy of the Substance Abuse Subtle Screening Inventory-3 (SASSI-3) was assessed among northern plains American Indians (AIs). The current study examined the efficacy of the SASSI-3 for identification of substance abuse in AIs. Northern plains AIs from 7 reservations participated in the study. Read More

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http://dx.doi.org/10.1037/ser0000413DOI Listing

Sex Offenders in Croatia: Fifteen Years Later.

Psychiatr Danub 2019 Dec;31(Suppl 5):826-830

Department of Forensic Psychiatry, University Psychiatric Hospital Vrapče, Bolnička cesta 3, 10000 Zagreb, Croatia,

Background: The aim of the study was to compare the characteristics of sex offenders today, and those who committed a sex crime fifteen years ago, in regard to their psychiatric-forensic aspects.

Subjects And Methods: Data from the University psychiatric hospital Vrapče, Center for forensic psychiatry on court people sent for psychiatric and forensic evaluation, who were accused of sex offense in two time frames (1998-2001 and 2010-2016) were analysed. In total there were 50 and 57 male subjects sent for an evaluation. Read More

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December 2019

Effects of plasma concentration of micro-RNA Mir-27b and CYP3A4*22 on equilibrium concentration of alprazolam in patients with anxiety disorders comorbid with alcohol use disorder.

Gene 2020 May 26;739:144513. Epub 2020 Feb 26.

Medical Academy of Continuous Professional Education of the Ministry of Health of the Russian Federation, 2/1 Barrikadnaya Street, Moscow 123995, Russian Federation.

Alprazolam is used in the treatment of patients with anxiety disorders comorbid with alcohol use disorder. Some proportion of these patients does not respond adequately to treatment with alprazolam, while many of them experience dose-dependent adverse drug reactions. Results of the previous studies have shown that CYP3A is involved in the biotransformation of alprazolam, the activity of which is dependent, inter alia, on the polymorphism of the encoding gene. Read More

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http://dx.doi.org/10.1016/j.gene.2020.144513DOI Listing

Lifestyles and sexuality in men and women: the gender perspective in sexual medicine.

Reprod Biol Endocrinol 2020 Feb 17;18(1):10. Epub 2020 Feb 17.

Department of Systems Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133, Rome, Italy.

Sexual health is strictly related with general health in both genders. In presence of a sexual dysfunction, the expert in sexual medicine aims to discover the specific weight of the physical and psychological factors can cause or con-cause the sexual problem. At the same time, a sexual dysfunction can represent a marker of the future development of a Non-communicable diseases (NCDss) as cardiovascular or metabolic diseases. Read More

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http://dx.doi.org/10.1186/s12958-019-0557-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7025405PMC
February 2020
2.409 Impact Factor

Evening chronotype as a discrete clinical subphenotype in bipolar disorder.

J Affect Disord 2020 Apr 26;266:556-562. Epub 2020 Jan 26.

Lindner Center of HOPE, Mason, OH, USA.; Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.

Objective: Our aim was to investigate evening chronotype, a proxy marker of circadian system dysfunction, as a clinical subphenotype in bipolar disorder (BD).

Methods: In this cross-sectional study, 773 BD participants and 146 control subjects were evaluated using the Structured Clinical Interview for DSM-IV and a set of questionnaires. Chronotype was determined using item-5 from the reduced Morningness-Eveningness Questionnaire. Read More

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http://dx.doi.org/10.1016/j.jad.2020.01.151DOI Listing

Violence and substance use in sexual minorities: Data from the Second Brazilian National Alcohol and Drugs Survey (II BNADS).

Arch Psychiatr Nurs 2020 02 12;34(1):41-48. Epub 2019 Nov 12.

Federal University of São Paulo (UNIFESP), Psychiatric Department, Brazil.

Objective: To describe the prevalence of substance use and the associations between adverse early life experiences, sexual behaviour and violence in sexual minority (SM) individuals.

Methods: The Brazilian National Alcohol and Drugs Survey is a probabilistic household survey performed in 2012, collecting data from 4067 Brazilians aged 14 years and older.

Results: 3. Read More

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http://dx.doi.org/10.1016/j.apnu.2019.11.003DOI Listing
February 2020

Hormonal responses in gambling versus alcohol abuse: A review of human studies.

Prog Neuropsychopharmacol Biol Psychiatry 2020 Jun 28;100:109880. Epub 2020 Jan 28.

Neuroeconomics Laboratory, Institut des Sciences Cognitives Marc Jeannerod, CNRS UMR 5229, Bron, France. Electronic address:

The endocrine system plays an essential role in communication between various organs of the body to maintain homeostasis. Both substance use disorders (SUDs) and non-substance abuse disrupt this system and lead to hormonal dysregulations. Here, we focus on the comparison between the function of the endocrine system in gambling disorders and alcohol addiction to understand the commonalities and differences in their neurobiological and psychological underpinnings. Read More

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http://dx.doi.org/10.1016/j.pnpbp.2020.109880DOI Listing

Density and Dichotomous Family History Measures of Alcohol Use Disorder as Predictors of Behavioral and Neural Phenotypes: A Comparative Study Across Gender and Race/Ethnicity.

Alcohol Clin Exp Res 2020 Mar 18;44(3):697-710. Epub 2020 Feb 18.

From the, Department of Psychiatry and Behavioral Sciences, (GP, JLM, DBC, AKP, CK, ME, DP, S Kinreich, SS-SV, BP), Downstate Medical Center, State University of New York, Brooklyn, New York.

Background: Family history (FH) is an important risk factor for the development of alcohol use disorder (AUD). A variety of dichotomous and density measures of FH have been used to predict alcohol outcomes; yet, a systematic comparison of these FH measures is lacking. We compared 4 density and 4 commonly used dichotomous FH measures and examined variations by gender and race/ethnicity in their associations with age of onset of regular drinking, parietal P3 amplitude to visual target, and likelihood of developing AUD. Read More

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http://dx.doi.org/10.1111/acer.14280DOI Listing

The effectiveness of substance use interventions for homeless and vulnerably housed persons:  A systematic review of systematic reviews on supervised consumption facilities, managed alcohol programs, and pharmacological agents for opioid use disorder.

PLoS One 2020 16;15(1):e0227298. Epub 2020 Jan 16.

C.T. Lamont Primary Health Care Research Centre, Bruyère Research Institute, Ottawa, ON, Canada.

Background: Substance use is disproportionately high among people who are homeless or vulnerably housed. We performed a systematic overview of reviews examining the effects of selected harm reduction and pharmacological interventions on the health and social well-being of people who use substances, with a focus on homeless populations.

Methods And Findings: We searched MEDLINE, EMBASE, PsycINFO, Joanna Briggs Institute EBP, Cochrane Database of Systematic Reviews and DARE for systematic reviews from inception to August 2019. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0227298PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964917PMC

Impact of opioid dose escalation on the development of substance use disorders, accidents, self-inflicted injuries, opioid overdoses and alcohol and non-opioid drug-related overdoses: a retrospective cohort study.

Addiction 2020 Jun 15;115(6):1098-1112. Epub 2020 Jan 15.

Division of Pharmaceutical Evaluation and Policy, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, AR, USA.

Aim: To understand the potential harmful effects of dose escalation among patients with chronic, non-cancer pain (CNCP) on chronic opioid therapy.

Design: Retrospective cohort study.

Setting: United States Veterans Healthcare Administration. Read More

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http://dx.doi.org/10.1111/add.14940DOI Listing

Psychiatric co-morbidity and asthma: A pilot study utilizing a free use tool to improve asthma care.

Clin Invest Med 2019 12 29;42(4):E22-E27. Epub 2019 Dec 29.

Department of Medicine, University of Alberta, Edmonton, AB.

Purpose: To assess the prevalence of co-morbid psychiatric disorders in asthmatic patients in a Western Canadian Regional Severe Asthma Center.

Methods: A prospective study was completed of patients evaluated through the Edmonton Regional Severe Asthma Clinic (ERSAC). A standardised evaluation, the Mini International Neuropsychiatric Interview (MINI) screen was used to identify possible psychiatric disorders. Read More

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http://dx.doi.org/10.25011/cim.v42i4.33115DOI Listing
December 2019

Mechanisms and moderators of intervention efficacy for soldiers with untreated alcohol use disorder.

J Consult Clin Psychol 2020 Feb;88(2):137-148

School of Social Work, University of Washington.

Objective: This research evaluates changes in perceived military and civilian drinking norms as mechanisms of the effects of a motivational enhancement therapy (MET) intervention on changes in alcohol consumption among active-duty military personnel with a substance use disorder. We also evaluate the value of providing tolerance and family history risk-related personalized feedback by testing whether those receiving feedback indicating higher risk reduce their drinking more than those receiving feedback indicating lower risk or receiving no feedback.

Method: Participants ( = 242; = 28 years; 92% male; 59% Caucasian) completed a baseline questionnaire and were randomly assigned to a MET or educational control condition. Read More

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http://dx.doi.org/10.1037/ccp0000471DOI Listing
February 2020

A Comprehensive Assessment of Vascular and Nonvascular Risk Factors Associated with Migraine.

Cureus 2019 Nov 18;11(11):e6189. Epub 2019 Nov 18.

Neurology, Cooper Neurological Institute, Cooper University Hospital, Camden, USA.

Introduction:  Migraine is a chronic disabling neurological disease, with an estimated expense of $15-20 million/year. Several studies with a small number of patients have studied risk factors for migraine such as cardiovascular disorders, stroke, smoking, demographic, and genetic factors but this is the first comprehensive study for evaluation of vascular and nonvascular risk factors. It is important to evaluate all the risk factors that help to prevent the healthcare burden related to migraine. Read More

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http://dx.doi.org/10.7759/cureus.6189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6919944PMC
November 2019

The Impact of Drug and Alcohol Intoxication on Glasgow Coma Scale Assessment in Patients with Traumatic Brain Injury.

World Neurosurg 2020 Mar 24;135:e664-e670. Epub 2019 Dec 24.

Department of General Surgery, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA; Norman E. McSwain, Jr, MD, Spirit of Charity Trauma Center, University Medical Center New Orleans, New Orleans, Louisiana, USA.

Background: The effect of intoxicating substances on assessment of Glasgow Coma Scale (GCS) in the trauma setting has not been completely elucidated.

Methods: A trauma registry was queried for patients with blunt head trauma in 2013-2017. Initial GCS score and toxicology screening from the database were reviewed. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.12.095DOI Listing

Children with Fetal Alcohol Syndrome (FAS): 3D-Analysis of Palatal Depth and 3D-Metric Facial Length.

Int J Environ Res Public Health 2019 12 21;17(1). Epub 2019 Dec 21.

Department of Orthodontics, University Hospital Münster, Albert-Schweitzer-Campus 1, 48149 Münster, Germany.

: Drinking alcohol during pregnancy can result in severe developmental disorders in the child. Symptoms of the fetal alcohol spectrum disorder (FASD) comprise growth deficiencies, abnormal facial phenotype and damage or dysfunction of the central nervous system. Numerous diagnostic methods for facial phenotyping in FASD exist, but diagnoses are still difficult. Read More

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http://dx.doi.org/10.3390/ijerph17010095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982319PMC
December 2019

Association of Childhood Attention Deficit Hyperactivity Disorder Symptoms with Academic and Psychopathological Outcomes in Indian College Students: a Retrospective Survey.

East Asian Arch Psychiatry 2019 Dec;29(124):124-128

National Institute of Mental Health and Neurosciences, Bangalore, India.

Objective: To survey the prevalence of retrospectively recalled clinically significant symptoms of attention deficit hyperactivity disorder (ADHD) in childhood and determine the association of ADHD symptoms in childhood with current academic achievement and psychopathological outcomes among college students in the state of Kerala, India.

Methods: A self-administered questionnaire was distributed to 5784 students from 58 colleges selected by cluster random sampling. The Barkley Adult ADHD Rating Scale-IV was used for recollection of childhood ADHD symptoms; a total score of ≥60 (indicating the 99 percentile) was taken as the cut-off for clinically significant ADHD symptoms in childhood. Read More

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http://dx.doi.org/10.12809/eaap1771DOI Listing
December 2019

Two case reports of fetal alcohol syndrome: broadening into the spectrum of cardiac disease to personalize and to improve clinical assessment.

Ital J Pediatr 2019 Dec 19;45(1):167. Epub 2019 Dec 19.

Center for Rare Diseases and Birth Defects, Department of Woman and Child Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Francesco Vito 8, 00168, Rome, IT, Italy.

Background: Fetal alcohol spectrum disorder (FASD) refers to a broad spectrum of disabilities, in infants and children, resulting from moderate to excessive prenatal alcohol exposure. Significant associations with alcohol exposure were already reported with congenital structural heart defects: i.e. Read More

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http://dx.doi.org/10.1186/s13052-019-0759-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923862PMC
December 2019

Driving Under the Influence of Marijuana and Illicit Drugs Among Persons Aged ≥16 Years - United States, 2018.

MMWR Morb Mortal Wkly Rep 2019 Dec 20;68(50):1153-1157. Epub 2019 Dec 20.

In the United States, driving while impaired is illegal. Nonetheless, an estimated 10,511 alcohol-impaired driving deaths occurred in 2018.* The contribution of marijuana and other illicit drugs to these and other impaired driving deaths remains unknown. Read More

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http://dx.doi.org/10.15585/mmwr.mm6850a1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936162PMC
December 2019

Three-year longitudinal cognitive functioning in patients recently diagnosed with bipolar disorder.

Acta Psychiatr Scand 2020 02 31;141(2):98-109. Epub 2019 Dec 31.

Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada.

Objective: The longitudinal course of neuropsychological functioning after the first manic episode in bipolar disorder is unknown. The present study evaluated cognitive change in bipolar disorder in the first 3 years after the initial manic episode.

Methods: Ninety-one newly diagnosed patients with bipolar disorder and 61 demographically similar healthy participants received a neuropsychological evaluation assessing multiple cognitive domains at baseline, 1-year, and 3-year time points. Read More

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http://dx.doi.org/10.1111/acps.13141DOI Listing
February 2020

Analysis of substance use and its outcomes by machine learning I. Childhood evaluation of liability to substance use disorder.

Drug Alcohol Depend 2020 Jan 22;206:107605. Epub 2019 Oct 22.

Department of Pharmaceutical Sciences, Computational Chemical Genomics Screen Center, School of Pharmacy, University of Pittsburgh, 3501 Terrace St, Pittsburgh, PA, 15213, USA; Department of Pharmaceutical Sciences, School of Pharmacy, NIDA National Center of Excellence for Computational Drug Abuse Research, University of Pittsburgh, 3501 Terrace St, Pittsburgh, PA, 15213, USA. Electronic address:

Background: Substance use disorder (SUD) exacts enormous societal costs in the United States, and it is important to detect high-risk youths for prevention. Machine learning (ML) is the method to find patterns and make prediction from data. We hypothesized that ML identifies the health, psychological, psychiatric, and contextual features to predict SUD, and the identified features predict high-risk individuals to develop SUD. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.107605DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6980708PMC
January 2020

Substance use, stressful life events and mental health: A longitudinal study among homeless women in Madrid (Spain).

Addict Behav 2020 04 30;103:106246. Epub 2019 Nov 30.

Universidad of Alcalá, Department of Social Psychology, Alcalá de Henares, Spain.

The objectives of this study were: (1) to assess the prevalence of substance use among homeless women; (2) to examine the correlates for drug abuse; (3) to analyze paths between early stressful life events, drug abuse and mental health. The methodology was a longitudinal study of women homeless in Madrid (Spain), who were followed for a 24 months period. There were 138 participants interviewed at baseline and 73 participants interviewed at follow-up. Read More

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http://dx.doi.org/10.1016/j.addbeh.2019.106246DOI Listing

Alcohol consumption patterns in young adults with type 1 diabetes: The SEARCH for diabetes in youth study.

Diabetes Res Clin Pract 2020 Jan 16;159:107980. Epub 2019 Dec 16.

Department of Pediatrics, University of Washington, OC.7.820 PO Box 5371, Seattle, WA, United States.

Aims: The objective of this study is to describe alcohol consumption behaviors of young adults with T1D and to examine associations between alcohol consumption and diabetes-related clinical markers.

Methods: Data from 602 SEARCH for Diabetes in Youth Study participants age ≥ 18 yrs. with T1D were collected from 12/2011 to 6/2015 (50% female, mean age 21. Read More

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http://dx.doi.org/10.1016/j.diabres.2019.107980DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002172PMC
January 2020

History of childhood abuse is associated with less positive treatment outcomes in socially stable women with alcohol use disorder.

BMC Womens Health 2019 12 12;19(1):159. Epub 2019 Dec 12.

Department of Psychology, University of Gothenburg, Göteborg, Sweden.

Background: To examine the relationship between treatment outcome, as measured according to change in alcohol consumption, and a history of childhood abuse (emotional, physical, sexual) in socially stable women undergoing treatment for alcohol use disorder (AUD).

Methods: Participants were assessed using the Addiction Severity Index and the Mini International Neuropsychiatric Interview at the beginning of treatment (n = 75), end of treatment (n = 59) and 12 month follow-up after treatment (n = 57). Self-report data on alcohol consumption were obtained at all three time-points using the Alcohol Habits Inventory-Revised 2. Read More

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http://dx.doi.org/10.1186/s12905-019-0857-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909489PMC
December 2019

Self-testing for liver disease - response to an online liver test questionnaire.

Scand J Gastroenterol 2020 Jan 10;55(1):67-73. Epub 2019 Dec 10.

Division of Clinical Bioinformatics, Division of Hepatology, Department of Medicine II, Heidelberg University, Heidelberg, Germany.

Elevated liver enzymes and chronic liver disease are associated with increased morbidity and mortality. Broad availability of internet questionnaires obtains representative insights into awareness of (chronic) liver disease in the general population. Also, these tools may be used to identify persons and populations at risk to prevent advanced liver disease. Read More

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http://dx.doi.org/10.1080/00365521.2019.1699600DOI Listing
January 2020

Consumption of psychoactive substances in prison: Between initiation and improvement, what trajectories occur after incarceration? COSMOS study data.

PLoS One 2019 4;14(12):e0225189. Epub 2019 Dec 4.

Centre for Evaluation and Information on Pharmacodependence, Clinical Pharmacology Department, Nantes University Hospital, France.

Background: Few studies have examined the consumption trajectories of inmates after entry to prison. The aim of this study was to assess the changes in the consumption of psychoactive substance between the period before detention and during incarceration and to characterize the profiles of prisoners with similar consumption trajectories during incarceration.

Methods And Findings: A multicenter, cross-sectional study was performed in all of the prisons from one region of France. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0225189PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892542PMC

Improved measurement of ethyl glucuronide concentrations in hair using UPLCMS/MS for the evaluation of chronic ethanol consumption.

Forensic Sci Int 2020 Jan 19;306:110071. Epub 2019 Nov 19.

Laboratory of Analytical Toxicology, Feevale University, Novo Hamburgo, Brazil; National Institute of Forensic Science and Technology (INCT Forense), Brazil; Graduate Program on Toxicology and Analytical Toxicology, Universidade Feevale, Novo Hamburgo, RS, Brazil. Electronic address:

The presence of Ethyl glucuronide (EtG) in hair provides a strong indication of ethanol consumption and its investigation is of interest in both clinical and forensic contexts because of the wide window of detection. However, due to the possibility of false negative results in cases of small ethanol intake or excessive hair washing, the combined measurement of ethyl palmitate (EtP) with EtG could be useful. In this study, a sensitive UHPLC-MS/MS procedure for the measurement of EtG in hair was developed and validated, using optimized sample preparation and chromatographic separation. Read More

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http://dx.doi.org/10.1016/j.forsciint.2019.110071DOI Listing
January 2020

The Assessment of Recovery Capital (ARC) predicts substance abuse treatment completion.

Addict Behav 2020 03 23;102:106189. Epub 2019 Oct 23.

Iowa Consortium for Substance Abuse Research and Evaluation, The University of Iowa, 2662 Crosspark Rd., Coralville, IA 52241, United States; Department of Psychiatry, Carver College of Medicine, The University of Iowa, 451 Newton Road 200, Medicine Administration Building, Iowa City, IA 52242, United States; Department of Biostatistics, College of Public Health, The University of Iowa, 145 N. Riverside Drive 100 CPHB, Iowa City, IA 52242, United States.

Recovery from addiction requires various personal and environmental resources. The purposes of this study were to determine if the Assessment of Recovery Capital (ARC) scores measured at admission could predict substance abuse treatment (SAT) completion and to identify personal and environmental factors associated with ARC scores. Participants (N = 2265) comprised clients entering a Midwestern SAT facility (August 2015 - June 2017). Read More

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http://dx.doi.org/10.1016/j.addbeh.2019.106189DOI Listing
March 2020
2.764 Impact Factor

Evaluation of traumatic brain injury patients with signs of alcohol intoxication.

Rev Col Bras Cir 2019 25;46(5):e20192272. Epub 2019 Nov 25.

Hospital do Trabalhador, Serviço de Cirurgia Geral, Curitiba, PR, Brasil.

Objetive: to evaluate the influence of alcohol intoxication in the time to perform head computed tomography and tomographic findings in traumatic brain injury patients.

Methods: a retrospective study of 183 traumatic brain injury patients, divided into two groups: 90 alcoholics and 93 non-alcoholics. Time interval from patient's arrival at emergency room to tomography was calculated for comparison between the groups, and tomographic findings were analyzed. Read More

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http://dx.doi.org/10.1590/0100-6991e-20192272DOI Listing
January 2020

Prescription of benzodiazepines, z-drugs, and gabapentinoids and mortality risk in people receiving opioid agonist treatment: Observational study based on the UK Clinical Practice Research Datalink and Office for National Statistics death records.

PLoS Med 2019 11 26;16(11):e1002965. Epub 2019 Nov 26.

Population Health Sciences, Bristol Medical School, Faculty of Health Sciences, University of Bristol, Bristol, United Kingdom.

Background: Patients with opioid dependency prescribed opioid agonist treatment (OAT) may also be prescribed sedative drugs. This may increase mortality risk but may also increase treatment duration, with overall benefit. We hypothesised that prescription of benzodiazepines in patients receiving OAT would increase risk of mortality overall, irrespective of any increased treatment duration. Read More

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http://dx.doi.org/10.1371/journal.pmed.1002965DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879111PMC
November 2019
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Evaluation of selective outcome reporting and trial registration practices among addiction clinical trials.

Addiction 2020 Jun 16;115(6):1172-1179. Epub 2020 Jan 16.

Oklahoma State University Center for Health Sciences, Tulsa, OK, USA.

Background And Aims: Selective outcome reporting occurs when trialists pre-specify primary and secondary outcomes during trial planning but alter the definitions in the published report. Here, we investigate selective outcome reporting in published addiction randomized controlled trials (RCTs) and evaluate whether particular funding sources are associated with an increased likelihood of selective outcome reporting.

Design: We conducted a cross-sectional study of published addiction clinical trials. Read More

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http://dx.doi.org/10.1111/add.14902DOI Listing

Implementation of a screening, brief intervention and referral to treatment programme for risky substance use in South African emergency centres: A mixed methods evaluation study.

PLoS One 2019 15;14(11):e0224951. Epub 2019 Nov 15.

Alan J Flisher Centre for Public Mental Health, Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa.

Background: Screening, brief intervention, and referral to treatment (SBIRT) for risky substance use is infrequently included in routine healthcare in low-resourced settings. A SBIRT programme, adopted by the Western Cape provincial government within an alcohol harm reduction strategy, employed various implementation strategies executed by a diverse team to translate an evidence-based intervention into services at three demonstration sites before broader programme scale-up. This paper evaluates the implementation of this programme delivered by facility-based counsellors in South African emergency centres. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0224951PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858052PMC
March 2020
3.234 Impact Factor

Alcohol consumption and consequences in adolescents in 68 low and middle-income countries - a multi-country comparison of risks by sex.

Drug Alcohol Depend 2019 Dec 25;205:107520. Epub 2019 Oct 25.

Centre for Youth Substance Abuse Research, Brisbane, The University of Queensland, QLD 4067, Australia. Electronic address:

Aims: Alcohol use is a leading risk factor for disease burden among youth. This study estimated sex differences in the prevalence of alcohol use and consequences among adolescents living in low and middle-income countries (LMIC).

Design: Multi-staged cross-sectional international standardized self-report questionnaires administered in the classroom. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2019.06.022DOI Listing
December 2019
3.423 Impact Factor

Reliability of the Addiction Severity Index self-report form (ASI-SR): a self-administered questionnaire based on the Addiction Severity Index composite score domains.

Nord J Psychiatry 2020 Jan 7;74(1):9-15. Epub 2019 Nov 7.

Department of Neuroscience, Uppsala University, Uppsala, Sweden.

The Addiction Severity Index (ASI) is a standardized interview used to assess problems associated with substance use. Although widely used, the time required for the interview remains an obstacle to its acceptance in many clinical settings. We examined if a self-administered questionnaire based on the composite score (CS) items, the ASI Self-Report form (ASI-SR), offers a reliable alternative to the ASI in assessing current substance use and related problems. Read More

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http://dx.doi.org/10.1080/08039488.2019.1666300DOI Listing
January 2020

Medication for addiction treatment and acute care utilization in HIV-positive adults with substance use disorders.

AIDS Care 2019 Nov 5:1-5. Epub 2019 Nov 5.

Boston Medical Center, Boston, MA, USA.

Medication for addiction treatment (MAT) could reduce acute care utilization in HIV-positive individuals with substance use disorders. The study objective was to determine if HIV-positive people with substance use disorders treated with MAT report less acute care utilization than those not receiving MAT. We assessed the association between MAT and acute care utilization among HIV-positive individuals with alcohol or opioid use disorder. Read More

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http://dx.doi.org/10.1080/09540121.2019.1683805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198361PMC
November 2019

Cannabinoids for the treatment of mental disorders and symptoms of mental disorders: a systematic review and meta-analysis.

Lancet Psychiatry 2019 12 28;6(12):995-1010. Epub 2019 Oct 28.

National Drug and Alcohol Research Centre, University of New South Wales, Sydney NSW, Australia. Electronic address:

Background: Medicinal cannabinoids, including medicinal cannabis and pharmaceutical cannabinoids and their synthetic derivatives, such as tetrahydrocannabinol (THC) and cannabidiol (CBD), have been suggested to have a therapeutic role in certain mental disorders. We analysed the available evidence to ascertain the effectiveness and safety of all types of medicinal cannabinoids in treating symptoms of various mental disorders.

Methods: For this systematic review and meta-analysis we searched MEDLINE, Embase, PsycINFO, the Cochrane Central Register of Controlled Clinical Trials, and the Cochrane Database of Systematic Reviews for studies published between Jan 1, 1980, and April 30, 2018. Read More

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http://dx.doi.org/10.1016/S2215-0366(19)30401-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949116PMC
December 2019
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Substance Use Disorder Education in Medical Schools: A Scoping Review.

Acad Med 2019 11;94(11):1825-1834

A. Muzyk is associate professor, Department of Pharmacy Practice, Campbell University College of Pharmacy and Health Sciences, Buies Creek, North Carolina, and associate professor of the practice of medical education, Duke University School of Medicine, Durham, North Carolina; ORCID: http://orcid.org/0000-0002-6904-2466. Z.P.W. Smothers is a second-year student, Doctor of Medicine Program, Duke University School of Medicine, Durham, North Carolina. D. Akrobetu is a second-year student, Doctor of Medicine Program, Duke University School of Medicine, Durham, North Carolina. J. Ruiz Veve is a third-year student, Doctor of Pharmacy Program, Campbell University College of Pharmacy and Health Sciences, Buies Creek, North Carolina. M. MacEachern is informationist, Taubman Health Sciences Library, University of Michigan, Ann Arbor, Michigan; ORCID: http://orcid.org/0000-0002-8872-1181. J.M. Tetrault is associate professor, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut. L. Gruppen is professor, Department of Learning Sciences, University of Michigan Medical School, Ann Arbor, Michigan; ORCID: http://orcid.org/0000-0002-2107-0126.

Purpose: As medical schools adapt their curricula to prepare future physicians for the opioid crisis and for treating patients with substance use disorders (SUDs), educators should refer to courses described in the literature. This scoping review aimed to (1) provide a comprehensive evaluation and summation of peer-reviewed literature reporting on SUD education in medical schools globally and (2) appraise the research quality and educational outcomes reported in SUD education studies in medical schools.

Method: The authors searched 6 databases (3 Ovid MEDLINE databases, Embase, ERIC, and Web of Science) from inception through May 25, 2018. Read More

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http://dx.doi.org/10.1097/ACM.0000000000002883DOI Listing
November 2019

Interprofessional Substance Use Disorder Education in Health Professions Education Programs: A Scoping Review.

Acad Med 2020 03;95(3):470-480

A. Muzyk is associate professor, Department of Pharmacy Practice, Campbell University College of Pharmacy and Health Sciences, Buies Creek, North Carolina, and associate professor of the practice of medical education, Duke University School of Medicine, Durham, North Carolina; ORCID: http://orcid.org/0000-0002-6904-2466. Z.P.W. Smothers is a third-year medical student, Doctor of Medicine Program, Duke University School of Medicine, Durham, North Carolina. K.M. Andolsek is professor, Department of Family Medicine and Community Health, Duke University School of Medicine, Durham, North Carolina. M. Bradner is associate professor, Department of Family Medicine and Population Health, Virginia Commonwealth University, Richmond Virginia. J.P. Bratberg is clinical professor, Department of Pharmacy Practice, University of Rhode Island College of Pharmacy, Kingston, Rhode Island. S.A. Clark is a Brown University Addiction Medicine Fellow, Department of Internal Medicine, Rhode Island Hospital, Providence, Rhode Island. K. Collins is a third-year pharmacy student, Doctor of Pharmacy Program, Campbell University College of Pharmacy and Health Sciences, Buies Creek, North Carolina. G.A. Greskovic is system director, Ambulatory Disease Management Programs, Geisinger Health System, Danville, Pennsylvania. L. Gruppen is professor, Department of Learning Sciences, University of Michigan Medical School, Ann Arbor, Michigan; ORCID: http://orcid.org/0000-0002-2107-0126. M. MacEachern is an informationist, Taubman Health Sciences Library, University of Michigan, Ann Arbor, Michigan; ORCID: http://orcid.org/0000-0002-8872-1181. S.E. Ramsey is associate professor (research), Departments of Psychiatry and Human Behavior and Medicine, Warren Alpert Medical School of Brown University and Rhode Island Hospital, Providence, Rhode Island; ORCID: https://orcid.org/0000-0001-7169-727X. J. Ruiz Veve is a fourth-year pharmacy student, Doctor of Pharmacy Program, Campbell University College of Pharmacy and Health Sciences, Buies Creek, North Carolina. J.M. Tetrault is associate professor, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut.

Purpose: The authors conducted this scoping review to (1) provide a comprehensive evaluation and summation of published literature reporting on interprofessional substance use disorder (SUD) education for students in health professions education programs and (2) appraise the research quality and outcomes of interprofessional SUD education studies. Their goals were to inform health professions educators of interventions that may be useful to consider as they create their own interprofessional SUD courses and to identify areas of improvement for education and research.

Method: The authors searched 3 Ovid MEDLINE databases (MEDLINE, In-Process & Other Non-Indexed Citations, and Epub Ahead of Print), Embase. Read More

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http://dx.doi.org/10.1097/ACM.0000000000003053DOI Listing

Dissemination of cognitive behavioral therapy for substance use disorders in the Department of Veterans Affairs Health Care System: Description and evaluation of Veteran outcomes.

Subst Abus 2019 Oct 23:1-7. Epub 2019 Oct 23.

Office of Mental Health and Suicide Prevention, U.S. Department of Veterans Affairs Central Office , Washington , DC , USA.

: As part of the nation's largest dissemination and implementation of evidence-based psychotherapies (EBPs) and the promotion of EBPs for substance use disorders (SUDs), the Veterans Health Administration (VHA) is working to nationally implement Cognitive Behavioral Therapy for SUD (CBT-SUD). The current manuscript describes the approach to system-wide training and reports Veteran outcomes associated with CBT-SUD implementation. : Four-hundred fifty-eight Veterans with a range of treatment goals received treatment through the Department of Veterans Affairs (VA) CBT-SUD Training Program. Read More

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http://dx.doi.org/10.1080/08897077.2019.1674238DOI Listing
October 2019
2 Reads

Change in treatment coverage and barriers to mental health care among adults with depression and alcohol use disorder: a repeat cross sectional community survey in Nepal.

BMC Public Health 2019 Oct 22;19(1):1350. Epub 2019 Oct 22.

Alan J Flisher Centre for Public Mental Health, Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa.

Background: Despite the availability of evidence-based treatment, there is a substantial gap between the number of individuals in need of mental health care and those who receive treatment. The aim of this study was to assess changes in treatment coverage and barriers to mental health care among adults with depression and alcohol use disorder (AUD) before and after implementation of a district mental health care plan (MHCP) in Nepal.

Methods: The repeat population-based cross-sectional community survey was conducted with randomly selected adults in the baseline (N = 1983) and the follow-up (N = 1499) surveys, 3 years and 6 months apart. Read More

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http://dx.doi.org/10.1186/s12889-019-7663-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6806507PMC
October 2019