3,813 results match your criteria Alcohol and Alcoholism [Journal]


Medical Conditions Linked to Atherosclerosis Are Associated With Magnified Cortical Thinning in Individuals With Alcohol Use Disorders.

Alcohol Alcohol 2020 May 23. Epub 2020 May 23.

Center for Imaging of Neurodegenerative Diseases (CIND), San Francisco VA Medical Center, San Francisco, CA, USA.

Aims: Magnetic resonance imaging (MRI) studies report widespread cortical thinning in individuals with alcohol use disorder (AUD), but did not consider potential effects of pro-atherogenic conditions such as hypertension, type 2 diabetes mellitus, hepatitis C seropositivity and hyperlipidemia on cortical thickness. The conditions are associated with regional cortical thinning in those without AUD. We predicted that individuals with concurrent AUD and pro-atherogenic conditions demonstrate the greatest regional cortical thinning in areas most vulnerable to decreased perfusion. Read More

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http://dx.doi.org/10.1093/alcalc/agaa034DOI Listing

Differential Effects of Saikosaponins A, B2, B4, C and D on Alcohol and Chocolate Self-Administration in Rats.

Alcohol Alcohol 2020 May 22. Epub 2020 May 22.

Neuroscience Institute, Section of Cagliari, National Research Council of Italy, Monserrato (CA), Italy.

Aims: Treatment with saikosaponin A (SSA)-an ingredient of the medicinal herb, Bupleurum falcatum-has been reported to suppress several addictive-like behaviors, including morphine, cocaine, alcohol and chocolate self-administration in male rats. The aim of this investigation was to investigate whether saikosaponins of B. falcatum other than SSA affect alcohol and chocolate self-administration in rats. Read More

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http://dx.doi.org/10.1093/alcalc/agaa049DOI Listing

Evaluation of Alcohol Industry Action to Reduce the Harmful Use of Alcohol: Case Study from Great Britain.

Alcohol Alcohol 2020 May 18. Epub 2020 May 18.

Institute of Clinical Psychology and Psychotherapy, TU Dresden, Dresden 01087, Germany.

Aims: To describe a case study in the British market of one of the global beer-producing companies that has set a target to increase the proportion of its products with an alcohol by volume (ABV) of 3.5% or less, and to reduce the mean ABV of its beer products.

Methods: Descriptive statistics and time-series analyses using Kantar Worldpanel's British household purchase data for 2015-2018. Read More

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http://dx.doi.org/10.1093/alcalc/agaa029DOI Listing

Alcohol and COVID-19.

Authors:
Jonathan Chick

Alcohol Alcohol 2020 May 13. Epub 2020 May 13.

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http://dx.doi.org/10.1093/alcalc/agaa039DOI Listing

Disulfiram Ethanol Reaction in a Patient Abstinent from Alcohol Caused by Hand Sanitizing.

Authors:
Avinash De Sousa

Alcohol Alcohol 2020 May 13. Epub 2020 May 13.

Lokmanya Tilak Municipal Medical College and General Hospital, Sion, Mumbai 400022, India.

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http://dx.doi.org/10.1093/alcalc/agaa038DOI Listing

New Methanol Poisoning Outbreaks in Iran Following COVID-19 Pandemic.

Alcohol Alcohol 2020 May 13. Epub 2020 May 13.

Internal Medicine Department, Faculty of Medicine, Tabriz University of Medical Sciences, Azadi Street, Tabriz, East Azerbaijan 5163639889, Iran.

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http://dx.doi.org/10.1093/alcalc/agaa036DOI Listing

Complicated Alcohol Withdrawal-An Unintended Consequence of COVID-19 Lockdown.

Alcohol Alcohol 2020 May 13. Epub 2020 May 13.

Centre for Addiction Medicine, Department of Psychiatry National Institute of Mental Health and Neurosciences (NIMHANS), Hosur Road, Bengaluru, 560029, India.

Aim: To assess the impact of COVID-19-related lockdown in India on alcohol-dependent persons.

Method: We examined the change in the incidence of severe alcohol withdrawal syndrome presenting to hospitals in the city of Bangalore.

Results: A changepoint analysis of the time series data (between 01. Read More

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http://dx.doi.org/10.1093/alcalc/agaa042DOI Listing

Are Patients With Alcohol Use Disorders at Increased Risk for Covid-19 Infection?

Authors:
Gianni Testino

Alcohol Alcohol 2020 May 13. Epub 2020 May 13.

Unit of Addiction and Hepatology, Alcohological Regional Centre, ASL3 c/o Polyclinic San Martino Hospital, Padiglione 10, Piazzale R Benzi 10, 16132 Genova, Italy.

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http://dx.doi.org/10.1093/alcalc/agaa037DOI Listing

Is Alcohol in Hand Sanitizers Absorbed Through the Skin or Lungs? Implications for Disulfiram Treatment.

Alcohol Alcohol 2020 May 13. Epub 2020 May 13.

Psychophysiology Research Unit, Free University of Brussels, Brussels, Belgium.

Aim: In view of the increase in the use of ethanol-containing hand sanitizers throughout the world due to the current COVID-19 pandemic, we wished to review the possible risks to patients treated with disulfiram, following a case report in which an apparent DER (disulfiram-ethanol reaction) was attributed to the cutaneous absorption of alcohol from hand sanitizers as well as by inhalation of vapour.

Method: Simple experiments to assess the levels of absorption by each route separately.

Results: Our results strongly suggest that while amounts of alcohol sufficient to cause a DER may be inhaled when hand sanitizers are used in confined spaces, absorption can be avoided by dispersal of the fumes, and absorption from the skin alone does not occur in pharmacologically significant quantities. Read More

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http://dx.doi.org/10.1093/alcalc/agaa045DOI Listing

Sharing Alcoholic Drinks and a COVID-19 Outbreak.

Alcohol Alcohol 2020 May 13. Epub 2020 May 13.

Dr DY Patil University, Pune, India.

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http://dx.doi.org/10.1093/alcalc/agaa028DOI Listing

Short- and Longer-Term Benefits of Temporary Alcohol Abstinence During 'Dry January' Are Not Also Observed Among Adult Drinkers in the General Population: Prospective Cohort Study.

Alcohol Alcohol 2020 May 11. Epub 2020 May 11.

Alcohol Change UK, London, UK.

Aims: The alcohol abstinence challenge 'Dry January' continues to grow, but there is a lack of knowledge of how Dry January participants compare to the general population. There is also a need to determine whether benefits experienced by Dry January participants are unique to that group or are also observed among other people.

Methods: We conducted a prospective cohort study using online questionnaires in early January, February and August 2019. Read More

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http://dx.doi.org/10.1093/alcalc/agaa025DOI Listing

Reduced Serum Levels of Cluster of Differentiation 200 in Alcohol-Dependent Patients.

Alcohol Alcohol 2020 May 4. Epub 2020 May 4.

Akhila Karnataka Jana Jagruthi Vedike, Shree Kshethra Dharmasthala Complex, Belthangady 574214, Dakshina Kannada District, Karnataka, India.

Aim: Chronic alcohol consumption can activate and dysregulate the neuroimmune system which leads to neuroinflammation. Neuroimmune regulatory proteins (NIReg) (e.g. Read More

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http://dx.doi.org/10.1093/alcalc/agaa033DOI Listing

Neuroprotective Effects of Grape Seed Procyanidins on Ethanol-Induced Injury and Oxidative Stress in Rat Hippocampal Neurons.

Alcohol Alcohol 2020 May 4. Epub 2020 May 4.

Department of Forensic Medicine, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou 450001, China.

Aims: Ethanol is a small molecule capable of interacting with numerous targets in the brain, the mechanisms of which are complex and still poorly understood. Studies have revealed that ethanol-induced hippocampal neuronal injury is associated with oxidative stress. Grape seed procyanidin (GSP) is a new type of antioxidant that is believed to scavenge free radicals and be anti-inflammatory. Read More

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http://dx.doi.org/10.1093/alcalc/agaa031DOI Listing

Performance of PEth Compared With Other Alcohol Biomarkers in Subjects Presenting For Occupational and Pre-Employment Medical Examination.

Alcohol Alcohol 2020 May 4. Epub 2020 May 4.

MVZ Labor Dessau GmbH, Bauhüttenstrasse 6, D-06847 Dessau-Roßlau, Germany.

Aims: To compare the performance of short- and long-term alcohol biomarkers for the evaluation of alcohol drinking in employment-related health controls.

Methods: The 519 blood samples originated from 509 patients (80% men) presenting at occupational health units and medical centers at employment agencies for the evaluation of risky drinking. The laboratory investigation comprised the measurement of phosphatidylethanol (PEth 16:0/18:1), carbohydrate-deficient transferrin (CDT; % disialotransferrin), gamma-glutamyl transferase (GGT), mean corpuscular volume (MCV), ethanol and ethyl glucuronide (EtG). Read More

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http://dx.doi.org/10.1093/alcalc/agaa027DOI Listing

Alcohol Consumption by Older New York City Residents: The Need for New Policies to Address Misuse.

Alcohol Alcohol 2020 Apr 29. Epub 2020 Apr 29.

Health System and Policy, Rutgers School of Public Health, 683 Hoes Lane West, Room 311, Piscataway, NJ 08854, USA.

Aims: The aim of this study is to assess risk factors for alcohol misuse among older New York City residents and examine the effect of local public health efforts to address alcohol misuse.

Methods: The Community Health Survey, a cross-sectional telephone survey of 8500 randomly selected adult New Yorkers, records the frequency of alcohol use. We examine these results among 65 and older subjects by sociodemographic status using logistic regression modeling and compare trends in smoking and alcohol consumption between 2002 and 2016. Read More

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http://dx.doi.org/10.1093/alcalc/agaa022DOI Listing

Inclusion of Cannabis Users in Alcohol Research Samples: Screening In, Screening Out, and Implications.

Alcohol Alcohol 2020 Apr 24. Epub 2020 Apr 24.

University of California, Los Angeles, Department of Psychology, Los Angeles, CA, USA.

Background: Alcohol and cannabis are frequently co-used, as 20-50% of those who drink alcohol report co-using cannabis. This study is based on the argument that alcohol researchers should enroll cannabis users in human laboratory studies of alcohol use disorder (AUD) to strengthen generalizability. This study examines how heavy drinking cannabis users differ from non-cannabis using heavy drinkers. Read More

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http://dx.doi.org/10.1093/alcalc/agaa023DOI Listing

Clinical Competencies for the Care of Hospitalized Patients with Alcohol Use Disorders.

Alcohol Alcohol 2020 Apr 22. Epub 2020 Apr 22.

Faculty of Medicine, University of Southampton, Southampton, UK.

Aims: The UK government aims to develop alcohol care teams (ACTs) that provide care for alcohol dependence in general hospital settings. Service descriptors have been identified to support the development of ACTs. The aim of this study was to use Delphi panel principles to identify the clinical competencies required to provide these elements of service. Read More

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http://dx.doi.org/10.1093/alcalc/agaa024DOI Listing

Factor, Concurrent and Predictive Validity of the Readiness to Change Questionnaire [Treatment Version] Among Non-Treatment-Seeking Individuals.

Alcohol Alcohol 2020 Apr 22. Epub 2020 Apr 22.

Latino Alcohol and Health Disparities Research and Training Center, University of Texas at El Paso, 500 West University Avenue, El Paso, TX 79968, USA.

Aims: This study assessed the factor, concurrent and predictive validity of the revised Readiness to Change Questionnaire [Treatment Version] (RCQ[TV]) among non-treatment-seeking individuals.

Methods: Non-treatment-seeking patients (Mage = 34.8, SD = 12. Read More

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http://dx.doi.org/10.1093/alcalc/agaa021DOI Listing

Psychophysiological Correlates of Emotional- and Alcohol-Related Cues Processing in Offspring of Alcohol-Dependent Patients.

Alcohol Alcohol 2020 Apr 17. Epub 2020 Apr 17.

Department of Psychiatry, Research Institute 12 de Octubre (i+12), Córdoba Ave. n/n, 28041 Madrid, Spain.

Aims: To determinate if offspring of alcohol-dependent patients (OA) process affective stimuli and alcohol-related cues in a different manner than control subjects do.

Methods: Event-related potentials (early posterior negativity [EPN]/ late positive potential [LPP]) and event-related oscillations (Theta) were obtained by electroencephalographic (EEG) recording during the viewing of International Affective Picture System (IAPS) images with positive, negative and neutral valence, as well as alcohol-related cues. The total sample was comprised of 60 participants, divided into two groups: one group consisted of OA (30) and the control group of participants with negative family history of alcohol use disorders (30). Read More

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http://dx.doi.org/10.1093/alcalc/agaa006DOI Listing

Change in the Relationship Between Drinking Alcohol and Risk of Violence Among Adolescents and Young Adults: A Nationally Representative Longitudinal Study.

Alcohol Alcohol 2020 Apr 17. Epub 2020 Apr 17.

Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Heath Park, Cardiff CF14 4XN, UK.

Aims: To quantify the relationship between alcohol and violence with increasing age.

Methods: Data were from The National Longitudinal Study of Adolescent to Adult Health (ADD Health) of 20,386 people representative of the US population. Mean age at the first wave of interviews was 16. Read More

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http://dx.doi.org/10.1093/alcalc/agaa020DOI Listing

Twenty Years Socioeconomic Trajectories in Older Adults with Varying Alcohol Use: A Register-Based Cohort Study.

Alcohol Alcohol 2020 Apr;55(3):304-314

Unit of Clinical Alcohol Research, Institute of Clinical Research, University of Southern Denmark, J.B. Winsløws Vej 20, entrance. 220 B, 5000 Odense, Denmark.

Aims: The objective of this paper was to examine 20-year trends of the socioeconomic status (SES) measures income and employment and their association with current alcohol use behaviors in Danish adults aged 60-70.

Methods: Data from The Danish National Health Survey 2013 and the baseline assessment of the Elderly Study (2013-2016) were combined to form four groups from the general population with various drinking patterns, but with no recent treatment for alcohol use disorder (AUD), and one group seeking treatment: Abstinent (n = 691), low- (n = 1978), moderate- (n = 602), and high-risk (HR) drinkers (n = 467), and DSM-5 AUD seeking treatment (n = 262). For all groups, Danish national register data were linked at the individual level obtain find annual information on income and employment during the 20 years prior to interview. Read More

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http://dx.doi.org/10.1093/alcalc/agaa019DOI Listing

The Decline in Alcohol Consumption in Russia from 2006 to 2017: Do Birth Cohorts Matter?

Alcohol Alcohol 2020 Apr;55(3):323-335

Department of Higher Mathematics, National Research University Higher School of Economics, 20 Myasnitskaya, Moscow 101000, Russian Federation.

Aim: Previous studies on youth drinking showed opposite trends for high-income and low-income countries. In Russia, a recent decline was observed in the prevalence of alcohol use, particularly among younger cohorts. This study aims at disentangling age and birth cohort effects to better understand the dynamics of abstinence and the volume of alcohol consumption. Read More

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http://dx.doi.org/10.1093/alcalc/agaa017DOI Listing

Chronic Alcohol Consumption Increased Bile Acid Levels in Enterohepatic Circulation and Reduced Efficacy of Irinotecan.

Alcohol Alcohol 2020 Apr;55(3):264-277

232 Waihuan Donglu, Guangzhou Daxuecheng, Panyu District, International Institute for Translational Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510006, PR China.

Aims: To investigate the effect of ethanol intake on the whole enterohepatic circulation (EHC) of bile acids (BAs) and, more importantly, on pharmacokinetics of irinotecan.

Methods: The present study utilized a mouse model administered by gavage with 0 (control), 240 mg/100 g (30%, v/v) and 390 mg/100 g (50%, v/v) ethanol for 6 weeks, followed by BA profiles in the whole EHC (including liver, gallbladder, intestine and plasma) and colon using ultra-high performance liquid chromatography with tandem mass spectrometry analysis. Pharmacokinetic parameters of irinotecan were measured after administration of irinotecan (i. Read More

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http://dx.doi.org/10.1093/alcalc/agaa005DOI Listing

Effects of Evaluative Conditioning on Implicit Evaluation of Alcohol and Drinking Behaviors: A Direct Replication.

Alcohol Alcohol 2020 Apr;55(3):299-303

Département de psychologie, Université de Poitiers, 86000 Poitiers, France.

Aims: Recent research suggests that evaluative conditioning (EC) can change implicit evaluations of alcohol and reduce drinking behaviors among college students (Houben et al., 2010a). This research has been conceptually replicated in two previous studies. Read More

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http://dx.doi.org/10.1093/alcalc/agaa009DOI Listing

Response to Dr Braillon.

Alcohol Alcohol 2020 04;55(3):338

Department Internal Medicine, Salem Medical Center and Center for Alcohol Research, University of Heidelberg.

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http://dx.doi.org/10.1093/alcalc/agaa016DOI Listing

Predictors of Readmission Following Outpatient Treatment for Alcohol Use Disorder.

Alcohol Alcohol 2020 Apr;55(3):291-298

Unit for Clinical Alcohol Research, Unit for Psychiatric Research, Department of Clinical Research, University of Southern Denmark, J.B. Winsløws Vej 18, 5000 Odense C.

Aims: To identify predictors of readmission to outpatient treatment for alcohol use disorder (AUD) with a view to identifying underlying mechanisms for preventing relapse.

Methods: A consecutive clinical cohort of 2130 AUD outpatients treated between 1 January 2006 and 1 June 2016 was studied. Data were collected by means of the Addiction Severity Index upon treatment entry and at discharge. Read More

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http://dx.doi.org/10.1093/alcalc/agaa018DOI Listing

Nalmefene as Needed Use Needs Evidence for Harm/Benefit Ratio.

Authors:
Alain Braillon

Alcohol Alcohol 2020 Apr;55(3):337

Alcohol treatment unit, University Hospital, avenue Laennec, 80000 Amiens, France.

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http://dx.doi.org/10.1093/alcalc/agaa015DOI Listing
April 2020
2.889 Impact Factor

Breathalyser-Based eHealth Data Suggest That Self-Reporting of Abstinence Is a Poor Outcome Measure for Alcohol Use Disorder Clinical Trials.

Alcohol Alcohol 2020 Apr;55(3):237-245

Department of Pharmaceutical Biosciences, Uppsala University, Box 591, 751 24 Uppsala, Sweden.

Aims: To evaluate the efficacy and monitoring capabilities of a breathalyser-based eHealth system for patients with alcohol use disorder (AUD) and to investigate the quality and validity of timeline follow-back (TLFB) as outcome measure in clinical trials and treatment.

Methods: Patients (n = 115) were recruited to clinical trials from a 12-step aftercare programme (12S-ABS) and from hospital care with abstinence (HC-ABS) or controlled drinking (HC-CDR) as goal and randomly divided into an eHealth and a control group. The effect of the eHealth system was analysed with TLFB-derived primary outcomes-change in number of abstinent days (AbsDay) and heavy drinking days (HDDs) compared to baseline-and phosphatidyl ethanol (PEth) measurements. Read More

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http://dx.doi.org/10.1093/alcalc/agaa004DOI Listing

Nurse-Delivered Screening and Brief Intervention Among College Students with Hazardous Alcohol Use: A Double-Blind Randomized Clinical Trial from India.

Alcohol Alcohol 2020 Apr;55(3):284-290

PGIMER, Psychiatry, Chandigarh, India.

Aim: To determine the effectiveness of individual-based, nurse-delivered, on-campus screening and brief intervention (SBI) for hazardous alcohol use among college students.

Methods: It was a parallel-design, double-blind, randomized controlled trial. Out of 793 students screened, 130 met the selection criteria of hazardous alcohol use, defined by alcohol use disorder identification test (AUDIT) score 8-19. Read More

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http://dx.doi.org/10.1093/alcalc/agaa014DOI Listing
April 2020
2.889 Impact Factor

Effects of Cocaine Exposure on Astrocytic Glutamate Transporters and Relapse-Like Ethanol-Drinking Behavior in Male Alcohol-Preferring Rats.

Alcohol Alcohol 2020 Apr;55(3):254-263

Department of Pharmacology and Experimental Therapeutics, College of Pharmacy and Pharmaceutical Sciences, University of Toledo, 3000 Arlington Ave, Toledo, OH, USA.

Aim: Glutamate has been considered as neurotransmitter that is critical in triggering relapse to drugs of abuse, including ethanol and cocaine. Extracellular glutamate concentrations are tightly regulated by several mechanisms, including reuptake through glutamate transporters. Glutamate transporter type 1 (GLT-1) is responsible for clearing the majority of extracellular glutamate. Read More

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http://dx.doi.org/10.1093/alcalc/agaa010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171926PMC

Alcohol Consumption by Beverage Type and Risk of Breast Cancer: A Dose-Response Meta-Analysis of Prospective Cohort Studies.

Alcohol Alcohol 2020 Apr;55(3):246-253

Department of Epidemiology and Statistics, College of Public Health, Zhengzhou University, 100 Science Avenue, Zhengzhou 450001, Henan, China.

Aims: Alcohol intake has been shown to increase the risk of breast cancer. However, the dose-response analysis of different alcoholic beverages (spirits, wine and beer) is not clear. Our meta-analysis aims to provide a dose-response estimation between different alcohols and breast cancer risk. Read More

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http://dx.doi.org/10.1093/alcalc/agaa012DOI Listing

Alcohol Use Disorder is Differently Associated with Psychotic Symptoms According to Underlying Psychiatric Disorders: A General Population Study.

Authors:
Hans Oh

Alcohol Alcohol 2020 Mar;55(2):233-234

University of Southern California, Suzanne Dworak Peck School of Social Work.

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http://dx.doi.org/10.1093/alcalc/agaa003DOI Listing

Lower Serum Magnesium Concentrations are associated With Specific Heavy Drinking Markers, Pro-Inflammatory Response and Early-Stage Alcohol-associated Liver Injury§.

Alcohol Alcohol 2020 Mar;55(2):164-170

Department of Medicine, University of Louisville, Louisville, KY, USA.

Aim: Chronic heavy alcohol intake frequently causes liver inflammation/injury, and altered mineral metabolism may be involved in this liver pathology. In this study, we evaluated the association of heavy drinking, changes in serum magnesium levels and biochemical evidence of liver injury in alcohol-use-disorder (AUD) patients who had no clinical signs or symptoms of liver injury. We also aimed to identify any sex-based differences in patients with mild or no biochemical evidence of liver injury induced by heavy drinking. Read More

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http://dx.doi.org/10.1093/alcalc/agaa001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082490PMC

Proteomic Analysis of Brain Regions Reveals Brain Regional Differences and the Involvement of Multiple Keratins in Chronic Alcohol Neurotoxicity.

Alcohol Alcohol 2020 Mar;55(2):147-156

Department of Forensic Medicine, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China.

Aims: Alcohol abuse has attracted public attention and chronic alcohol exposure can result in irreversible structural changes in the brain. The molecular mechanisms underlying alcohol neurotoxicity are complex, mandating comprehensive mining of spatial protein expression profile.

Methods: In this study, mice models of chronic alcohol intoxication were established after 95% alcohol vapor administration for 30 consecutive days. Read More

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http://dx.doi.org/10.1093/alcalc/agaa007DOI Listing

Baclofen: A Game Changer in the Treatment of Alcohol Dependence.

Alcohol Alcohol 2020 Feb;55(1):46-47

Department of Psychiatry, Amsterdam University Medical Centers, location Academic Medical Center, Meibergdreef 5, 1105AZ Amsterdam, The Netherlands.

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http://dx.doi.org/10.1093/alcalc/agz085DOI Listing
February 2020

The Association between Reward Sensitivity and Activity Engagement: the Influence of Delay Discounting and Anhedonia.

Alcohol Alcohol 2020 Mar;55(2):215-224

Tilburg University, Department of Developmental Psychology, Warandelaan 2, 5000 LE Tilburg, The Netherlands.

Aim: Reward sensitivity affects individuals' motivation to engage in goal-directed behavior. Other concepts, critical for reward appraisal, that potentially influence activity participation encompass delay discounting and anhedonia. The aim of this study was to test the hypothesis that anhedonia and delay discounting influence the relationship between reward sensitivity and activity engagement. Read More

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http://dx.doi.org/10.1093/alcalc/agz105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082492PMC

Alcohol Tolerance in Human Laboratory Studies for Development of Medications to treat Alcohol Use Disorder.

Alcohol Alcohol 2020 Mar;55(2):129-135

Department of Behavioral and Social Sciences, Center for Alcohol and Addiction Studies, School of Public Health, Brown University, 121 South Main Street, Providence, RI 02912, USA.

Aims: Human laboratory studies have contributed extensively in the research and development of novel medications to treat alcohol use disorder (AUD). Alcohol tolerance may represent one additional variable that can be utilized to expand the understanding of the AUD wide phenotypic profile and provide support to the medication development process. Tolerance is characterized as an individual's subjective response to alcohol and has been recognized as a predictor of AUD progression. Read More

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http://dx.doi.org/10.1093/alcalc/agz103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082491PMC

Perceptions of Alcohol Health Warning Labels by Governments: Too Effective for Implementation!

Authors:
Alain Braillon

Alcohol Alcohol 2020 Apr;55(3):336

Alcohol treatment unit, University hospital, ave Laennec, 80000 Amiens, France.

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http://dx.doi.org/10.1093/alcalc/agz107DOI Listing
April 2020
2.889 Impact Factor

Home-Based Contingency Management Delivered by Community Health Workers to Improve Alcohol Abstinence: A Randomized Control Trial.

Alcohol Alcohol 2020 Mar;55(2):171-178

Department of Health Care Policy and Management, Graduate School of Comprehensive Human Sciences, Tsukuba University, Tenno-dai, Tsukuba, Ibaraki 305-8575, Japan.

Aim: To evaluate the effectiveness of home-based contingency management (CM) in improving abstinence in an incentive-dependent manner among alcoholic individuals.

Methods: A 12-week, home-visit (HV) only controlled, randomized incentive-ranging trial of 161 adults with current alcohol dependence was recruited using social network theory techniques. Participants randomly received HV, low- (CM-L) or higher-magnitude CM (CM-H). Read More

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http://dx.doi.org/10.1093/alcalc/agz106DOI Listing

Efficacy of an Internet-Based Community Reinforcement and Family Training Program to Increase Treatment Engagement for AUD and to Improve Psychiatric Health for CSOs: A Randomized Controlled Trial.

Alcohol Alcohol 2020 Mar;55(2):187-195

Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet, SE171 77 Stockholm, Sweden.

Aims: Community Reinforcement Approach and Family Training (CRAFT) is a support program for concerned significant others (CSOs) to identified persons (IPs) with alcohol use disorders, with the purpose of engaging IPs to treatment and to improve CSO functioning. The purpose of the present study was to investigate the efficacy of an internet-based version of CRAFT (iCRAFT).

Methods: Randomized controlled trial comparing iCRAFT with a wait-list (WL) condition with a nation-wide uptake in Sweden. Read More

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http://dx.doi.org/10.1093/alcalc/agz095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082489PMC

Alcohol Sponsorship and Esports: Reinforcing the Need for Legislative Restrictions on Alcohol Sponsorship.

Authors:
Tim Chambers

Alcohol Alcohol 2020 Mar;55(2):144-146

Imperial College London, Centre for Health Economics and Policy Innovation, School of Business, London, UK.

Alcohol sponsorship in esports is on the rise. Many esports athletes and viewers are children and young people. Alcohol sponsorship of esports places millions of children and young people at risk of alcohol-related harm. Read More

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http://dx.doi.org/10.1093/alcalc/agz104DOI Listing

Meta-Analysis of the Prevalence of HBV Infection Among Alcohol Users Worldwide.

Alcohol Alcohol 2020 Mar;55(2):136-143

Laboratorio de Investigacao Medica em Hepatologia por Virus (LIM-47), Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil.

Aims: To investigate the prevalence of hepatitis B virus (HBV) infection among alcohol users.

Methods: A systematic search of articles in the PubMed, Web of Science and EMBASE databases was conducted. The methodological quality of each study was scored, and a meta-analysis was performed taking into account the heterogeneity expected among the studies. Read More

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http://dx.doi.org/10.1093/alcalc/agz102DOI Listing

Identification of Alcohol Risk Drinking Behaviour in Pregnancy Using a Web-Based Questionnaire: Large-Scale Implementation in Antenatal Care.

Alcohol Alcohol 2020 Mar;55(2):225-232

Department of Obstetrics and Gynaecology, Odense University Hospital, Sdr. Boulevard 29, DK-5000 Odense C, Denmark.

Aims: This study aimed to examine the feasibility of a web-based questionnaire when collecting information on alcohol consumption in pregnancy to identify women with risk drinking behaviour, and to describe factors associated with risk drinking behaviour, and the use of specialized care for prenatal risk drinking.

Methods: In 2413 women referred to antenatal care at Odense University Hospital, Denmark, April-October 2018, self-reported alcohol intake was retrieved from a web-based questionnaire. Replies were screened for risk drinking behaviour: current intake of ≥7 drinks/week, ≥3 binge drinking episodes (intake of ≥5 drinks on a single occasion) in pregnancy, binge drinking after recognition of pregnancy and/or a TWEAK-score ≥ 2 points. Read More

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http://dx.doi.org/10.1093/alcalc/agz100DOI Listing

Platelet-Derived Growth Factor C in Alcoholics.

Alcohol Alcohol 2020 Mar;55(2):157-163

Servicio de Medicina Interna, Universidad de La Laguna, Tenerife, Canary Islands, Spain.

Aims: Platelet-derived growth factor (PDGF) promotes liver collagen deposition, acting on hepatic stellate cells. Despite this, low serum PDGF levels were reported in chronic hepatitis C or B infection, although some studies yield the opposite result. Since PDGF may be related not only to fibrosis but also with vascular, neuronal or muscle disease, it is important to analyze its behavior in alcoholics. Read More

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http://dx.doi.org/10.1093/alcalc/agz094DOI Listing

Adverse Childhood Experiences are Associated with High-Intensity Binge Drinking Behavior in Adulthood and Mediated by Psychiatric Disorders.

Alcohol Alcohol 2020 Mar;55(2):204-214

Section on Clinical Genomics and Experimental Therapeutics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, 10 Center Drive (10CRC/2-2352), Bethesda, MD 20892-1540, USA.

Aim: High-intensity binge drinking (HIBD), defined as two or more times the gender-specific binge threshold, is rapidly increasing in the USA; however, the underlying contributing factors are poorly understood. This study investigated the relationship of adverse childhood experiences (ACEs) and HIBD.

Methods: Two independent, cross-sectional samples were analysed: (a) past 12-month drinkers in the National Epidemiological Survey on Alcohol and Related Conditions-III (NESARC-III; n = 25,552) and (b) the National Institute on Alcohol Abuse and Alcoholism (NIAAA) clinical sample (n = 1303). Read More

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http://dx.doi.org/10.1093/alcalc/agz098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082493PMC

Perceptions of Alcohol Health Warning Labels in a Large International Cross-Sectional Survey of People Who Drink Alcohol.

Alcohol Alcohol 2020 Apr;55(3):315-322

Department of Psychology, Oxford Brookes University, Gipsy Lane, Oxford, UK.

Aims: This paper aimed to explore perceptions of alcohol health warning labels amongst a large international sample of people who drink alcohol.

Methods: The Global Drug Survey (GDS) is the world's largest annual cross sectional survey of drug use. Seven health warning labels were presented (relating to heart disease, liver, cancer, calories, violence, taking two days off and the myth of benefits to moderate drinking). Read More

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http://dx.doi.org/10.1093/alcalc/agz099DOI Listing