3,673 results match your criteria Alcohol and Alcoholism [Journal]


Pellagra and Alcohol Dependence Syndrome: Findings From a Tertiary Care Addiction Treatment Centre in India.

Alcohol Alcohol 2019 Feb 5. Epub 2019 Feb 5.

Centre for Addiction Medicine, Department of Psychiatry National Institute of Mental Health and Neurosciences (NIMHANS), Hosur Road, Bengaluru, India.

Aim: To define the prevalence and clinical presentation of pellagra, a multi-systemic disease caused by the deficiency of niacin, in patients admitted to a tertiary addiction treatment centre in southern India, with alcohol dependence syndrome (ADS)-(ICD10).

Methods: Review of the health records of 2947 patients who received inpatient care for ADS between 2015 and 2017.

Results: Out of 2947, 31 (1%) were diagnosed with pellagra. Read More

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http://dx.doi.org/10.1093/alcalc/agz004DOI Listing
February 2019
3 Reads

How to Interpret Hair EtG Concentrations in Individuals with High Body Mass Index? Brief Commentary on: Influence of Body Mass Index on Hair Ethyl Glucuronide Concentrations.

Alcohol Alcohol 2019 Feb 5. Epub 2019 Feb 5.

Toxicological Center, Antwerp University, Antwerp, Belgium.

Body mass index (BMI) is a variable that complicates the interpretation of the alcohol metabolite ethyl glucuronide (EtG) in hair. However, direction on how EtG should currently be interpreted within individuals consuming moderate and excessive daily amounts of alcohol related to their BMI is lacking. In light of interpretation of EtG in individuals with high BMI, we present post hoc analysis of earlier data regarding the effect of BMI on hair EtG concentrations. Read More

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http://dx.doi.org/10.1093/alcalc/agz006DOI Listing
February 2019

The Methanol Poisoning Outbreaks in Iran 2018.

Alcohol Alcohol 2019 Jan 31. Epub 2019 Jan 31.

Department of Health in Emergencies and Disasters, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

Aims: To present epidemiological data, probable causes and lessons learned from the outbreak of methanol poisoning in Iran in September 2018, and relate this to the increasing incidence of methanol poisoning worldwide over recent decades.

Method: Analysis of all available reliable field information, official news reports and reports from the country's forensic medicine organization and the Ministry of Health.

Results: Overall, 768 people in Iran were documented as poisoned from September 7 to October 7 2018 by consuming an informal alcohol containing methanol, of whom 76 died (10. Read More

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https://academic.oup.com/alcalc/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/alcalc/agz005DOI Listing
January 2019
1 Read

Does Self-Reported or Behavioral Impulsivity Predict Subjective Response to Low-Dose Alcohol?

Alcohol Alcohol 2019 Jan 11. Epub 2019 Jan 11.

Department of Psychiatry, School of Medicine, Yale University, 34 Park Street, New Haven, CT, USA.

Aims: Subjective response to alcohol and impulsivity are both independent predictors of alcohol use and may be related risk factors for alcohol use disorders (AUDs). Recent findings suggest that more impulsive individuals may experience higher risk subjective response patterns at moderate-to-high doses of alcohol. However, whether these relationships are observable early in a drinking occasion remains an open question. Read More

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http://dx.doi.org/10.1093/alcalc/agy092DOI Listing
January 2019
1 Read

Unhelpful Prescribing in Alcohol Use Disorder: Risk and Averting Risk.

Authors:
Jonathan Chick

Alcohol Alcohol 2019 01;54(1):1-4

Castle Craig Hospital, Scotland, UK

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http://dx.doi.org/10.1093/alcalc/agy090DOI Listing
January 2019
2 Reads

Individual and Social Factors Related to Trajectories of Blackouts among Underage Drinkers in the Emergency Department.

Alcohol Alcohol 2019 Jan 4. Epub 2019 Jan 4.

Addiction Center, University of Michigan Department of Psychiatry, Ann Arbor, MI.

Aims: Alcohol-related blackouts can result in acute injuries and other negative outcomes. Among underage risky drinkers, we examined longitudinal trajectories of blackout frequency following an emergency department (ED) visit, and identified baseline characteristics associated with blackout trajectory membership.

Methods: Participants (ages 14-20; N = 836) attending an ED who screened positive for risky drinking and enrolled in a randomized-controlled trial of brief alcohol interventions were assessed at baseline, 3-, 6-, and 12-months. Read More

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https://academic.oup.com/alcalc/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/alcalc/agy087DOI Listing
January 2019
6 Reads

3D Analysis of Philtrum Depth in Children with Fetal Alcohol Syndrome.

Alcohol Alcohol 2019 Jan 4. Epub 2019 Jan 4.

Department of Orthodontics, University of Münster, Albert-Schweitzer-Campus 1, Münster, Germany.

Aims: Diagnosis of fetal alcohol spectrum disorder (FASD) is complex and difficult. The estimated number of unreported FASD is thus assumed to be substantial. In our cross-sectional study, we aimed to identify possible metric differences in philtrum depth in children with fetal alcohol syndrome (FAS) compared to healthy controls based on non-invasive 3D facial scanning in order to provide an objective, metrical tool improving FASD diagnosis. Read More

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http://fdslive.oup.com/www.oup.com/pdf/production_in_progres
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http://dx.doi.org/10.1093/alcalc/agy088DOI Listing
January 2019
6 Reads

Executive Functioning Moderates Responses to Appetitive Cues: A Study in Severe Alcohol Use Disorder and Alcoholic Liver Disease.

Alcohol Alcohol 2019 Jan;54(1):38-46

Department of Psychology, NHMRC Centre of Research Excellence in Mental Health and Substance Use, Macquarie University, NSW, Australia.

Aim: To examine subjective and psychophysiological responses to appetitive cues during an alcohol cue reactivity task, and its relation to alcoholic liver disease and assess whether executive functioning is associated with appropriate regulation of cue-elicited responses in individuals with severe alcohol use disorder (AUD).

Methods: Seventeen treatment-seeking alcoholic liver disease patients and a control group of treatment-seeking severe AUD participants completed neuropsychological executive functioning measures (Stroop task; Trail-making test) and the cue reactivity task, whereby control (water) and alcohol beverage cues were presented, followed by respective recovery periods. Subjective alcohol craving and heart rate variability were recorded across the task. Read More

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https://academic.oup.com/alcalc/article/54/1/38/5253747
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http://dx.doi.org/10.1093/alcalc/agy083DOI Listing
January 2019
2 Reads

Healthcare Utilisation, Morbidities and Alcohol Use Monitoring Prior to Alcoholic Psychosis Diagnosis.

Alcohol Alcohol 2018 Dec 20. Epub 2018 Dec 20.

Division of Primary Care, School of Medicine, University of Nottingham, University Park, Nottingham, UK.

Aims: The aim of this study was to describe healthcare utilisation, morbidities and monitoring of alcohol use in patients prior to a diagnosis of alcoholic psychosis in order to inform the early identification of patients at risk.

Methods: Using linked general practice and hospitalisation data in England (April 1997 to June 2014), we identified 1731 individuals (≥18 years) with a clinical recorded diagnosis of alcoholic psychosis and 17,310 matched controls without the disorder, we examined all prior general practitioner (family doctor) visits, hospitalisations, medically recorded morbidities and alcohol assessment/interventions records. Poisson regression models were used to compare rates of healthcare utilisation in people with alcoholic psychosis to those without. Read More

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http://dx.doi.org/10.1093/alcalc/agy085DOI Listing
December 2018
7 Reads

Higher Creatinine Concentrations in Ethyl Glucuronide-Positive Urine Specimens Collected from Subjects in a Controlled Alcohol Abstinence Program: Is Serum Creatinine a Good Marker of Renal Function in Drinkers?

Alcohol Alcohol 2019 Jan;54(1):19-22

Department of Toxicology & Forensic Toxicology, SYNLAB MVZ Weiden GmbH, Zur Kesselschmiede 4, Weiden, Germany.

Aims: The aim of this study was to examine urine creatinine concentrations in drivers submitted to controlled alcohol abstinence programs.

Methods: Urine samples (n = 32,210) were screened for ethyl glucuronide (EtG) by immunoassay during a 2-year period. Non-negatives underwent EtG and ethyl sulfate (EtS) confirmation by coupled-column Liquid Chromatography-Tandem Mass Spectrometry. Read More

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http://dx.doi.org/10.1093/alcalc/agy084DOI Listing
January 2019
1 Read

Maximum Time Between Tests: A Digital Biomarker to Detect Therapy Compliance and Assess Schedule Quality in Measurement-Based eHealth Systems for Alcohol Use Disorder.

Alcohol Alcohol 2019 Jan;54(1):70-72

Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden.

Aim: To evaluate, in a breathalyzer-based eHealth system, whether the time-based digital biomarker 'maximum time between tests' (MTBT) brings valuable information on alcohol consumption patterns as confirmed by correlation with blood phosphatidyl ethanol (PEth), serum carbohydrate deficient transferrin (CDT) and timeline follow-back data.

Method: Data on 54 patients in follow-up for treatment of alcohol use disorder were analysed.

Results: The model of weekly averages of 24-log transformed MTBT adequately described timeline follow-back data (P  <  0. Read More

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http://dx.doi.org/10.1093/alcalc/agy086DOI Listing
January 2019
2 Reads

A Review of Baclofen Overdoses in Australia: Calls to a Poisons Information Centre and a Case Series.

Alcohol Alcohol 2019 Jan;54(1):73-78

Drug Health Services, Royal Prince Alfred Hospital, NSW, Australia.

Aim: to describe trends in baclofen reports to Australia's largest Poisons Information Centre (PIC) and present a case series detailing severity of overdoses.

Short Summary: PBS data demonstrates baclofen use is increasing in Australia, while calls to NSWPIC illustrate an increase in number of exposures associated with toxicity. Baclofen toxicity may require prolonged intensive care admission. Read More

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http://dx.doi.org/10.1093/alcalc/agy082DOI Listing
January 2019
2 Reads

Inhibition by Ethanol of Shear Stress-Induced Formation of Platelet Thrombi in Whole Blood.

Alcohol Alcohol 2019 Jan;54(1):13-18

Department of Environmental and Preventive Medicine, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan.

Aims: The risk of thromboatherosclerotic disease is lower in moderate drinkers than in non-drinkers. We investigated the effects of ethanol on platelet aggregation under a condition with shear stress.

Short Summary: Shear stress-induced formation of platelet thrombi is inhibited by ethanol at its attainable concentrations after drinking. Read More

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http://dx.doi.org/10.1093/alcalc/agy081DOI Listing
January 2019
13 Reads

Effects of Moderate Ethanol Consumption on Lipid Metabolism and Inflammation Through Regulation of Gene Expression in Rats.

Alcohol Alcohol 2019 Jan;54(1):5-12

School of Exercise and Nutritional Sciences, San Diego State University, San Diego, CA, USA.

Aims: Epidemiological studies and experimental data from rodent models have reported a non-linear relationship between consumption of alcohol and cardiovascular disease (CVD) risk that suggests that light-to-moderate drinking as opposed to excessive consumption may provide some cardiovascular benefits. The present study examined potential mechanisms by which moderate alcohol consumption may provide a protective effect against CVD.

Short Summary: Wistar rats exposed for 3 months to a 20% ethanol intermittent-access voluntary drinking paradigm displayed a reduction in epididymal fat, blood glucose and non-HDL and total cholesterol. Read More

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https://academic.oup.com/alcalc/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/alcalc/agy079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324654PMC
January 2019
12 Reads

Executive Dysfunction in Patients With Korsakoff's Syndrome: A Theory-Driven Approach.

Alcohol Alcohol 2019 Jan;54(1):23-29

Donders Institute for Brain, Cognition and Behaviour, Radboud University, Montessorilaan 3, Nijmegen, The Netherlands.

Aims: In addition to amnesia, executive deficits are prominent in Korsakoff's syndrome (KS), yet poorly studied. This study investigates the degree of executive dysfunction in patients with KS for the three main executive subcomponents shifting, updating and inhibition using novel, theory-driven paradigms.

Short Summary: Compared to healthy controls, patients with KS show impairments on the executive subcomponents shifting and updating, but not on inhibition. Read More

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http://dx.doi.org/10.1093/alcalc/agy078DOI Listing
January 2019
10 Reads

Reply to: Effects of a Comprehensive Pro-alcohol Policy in Washington State.

Alcohol Alcohol 2019 Jan;54(1):120-121

Alcohol Research Group, Public Health Institute, 6001 Shellmound Ave, Suite 450, Emeryville, CA, USA.

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https://academic.oup.com/alcalc/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/alcalc/agy077DOI Listing
January 2019
2 Reads

Effects of a Comprehensive Pro-alcohol Policy in Washington State.

Authors:
Alain Braillon

Alcohol Alcohol 2019 Jan;54(1):119-121

Department of Medicine, Alcohol Treatment Unit, University Hospital, Amiens, France.

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http://dx.doi.org/10.1093/alcalc/agy076DOI Listing
January 2019
1 Read
2.889 Impact Factor

Dynamic Features of Problematic Drinking: Alcohol Use Disorder Latent Classes Across Ages 18-64.

Alcohol Alcohol 2019 Jan;54(1):97-103

Department of Biobehavioral Health and the Edna Bennett Pierce Prevention Research Center, The Pennsylvania State University, 314 Biobehavioral Health, University Park, PA, USA.

Aims: Alcohol use disorders (AUDs) are linked with numerous severe detrimental outcomes. Evidence suggests that there is a typology of individuals with an AUD based on the symptoms they report. Scant research has identified how these groups may vary in prevalence by age, which could highlight aspects of problematic drinking behavior that are particularly salient at different ages. Read More

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http://fdslive.oup.com/www.oup.com/pdf/production_in_progres
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http://dx.doi.org/10.1093/alcalc/agy074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324653PMC
January 2019
23 Reads

Patterns in Reduction or Cessation of Drinking in Australia (2001-2013) and Motivation for Change.

Alcohol Alcohol 2019 Jan;54(1):79-86

Centre for Population Health, Burnet Institute, Melbourne, Australia.

Aims: This paper examines: (a) change over time (2001-2013) in recently reducing or ceasing drinking in the Australian population and (b) the reasons given for reducing or ceasing drinking in the most recent survey (2013); stratified by sex and age group.

Short Summary: Rates of reducing and ceasing drinking increased between 2001 and 2013 in Australia. Young people were more likely to modify drinking due to lifestyle and enjoyment reasons; older groups were more likely to report health reasons. Read More

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https://academic.oup.com/alcalc/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/alcalc/agy072DOI Listing
January 2019
7 Reads

Stress and Alcohol Priming of Brain Toll-Like Receptor Signaling in Alcohol Use Disorder.

Alcohol Alcohol 2018 Nov;53(6):639-641

Bowles Center for Alcohol Studies, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

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http://dx.doi.org/10.1093/alcalc/agy061DOI Listing
November 2018
1 Read

Alcohol and Alcoholism: Then, Now and The Future of 'The Red Journal'.

Alcohol Alcohol 2018 Nov;53(6):637-638

Alcohol and Alcoholism Editorial Office.

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http://dx.doi.org/10.1093/alcalc/agy075DOI Listing
November 2018
1 Read

Malocclusion Can Give Additional Hints for Diagnosis of Fetal Alcohol Spectrum Disorder.

Alcohol Alcohol 2019 Jan;54(1):56-61

Department of Orthodontics, University Münster, Albert-Schweitzer-Campus 1, Münster, Germany.

Aims: Fetal alcohol spectrum disorder (FASD) is a developmental disorder caused by maternal alcohol intake (prevalence: 0.77%). Malocclusion has been described in case reports of patients with FASD, but reliable evidence for associations between FASD and malocclusion is not documented. Read More

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https://academic.oup.com/alcalc/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/alcalc/agy071DOI Listing
January 2019
20 Reads

Transitions Through Stages of Alcohol Use, Use Disorder and Remission: Findings from Te Rau Hinengaro, The New Zealand Mental Health Survey.

Alcohol Alcohol 2019 Jan;54(1):87-96

Department of Psychological Medicine, Dunedin School of Medicine, University of Otago, 464 Cumberland St., Dunedin, New Zealand.

Aims: To understand transitions from alcohol use to disorder, we examine timing of transitions between stages of alcohol use and associations between transitions and socio-demographic factors.

Short Summary: Using nationally representative data, we found that the majority of alcohol use disorders develop by age 25. Increased alcohol use within a participant's cohort was associated with subsequent transition across all stages of alcohol use and disorder. Read More

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https://academic.oup.com/alcalc/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/alcalc/agy069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324656PMC
January 2019
16 Reads

The Incidence of Alcoholism in Patients with Advanced Cancer Receiving Active Treatment in Two Tertiary Care Centers in Italy.

Alcohol Alcohol 2019 Jan;54(1):47-50

Medical Oncology Unit, University of L'Aquila, L'Aquila, Italy.

Introduction: Substance abuse is frequently under-diagnosed among cancer patients. Alcoholism is a problem afflicting about 18% of the general population. This percentage is higher in hospitalized patients. Read More

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http://dx.doi.org/10.1093/alcalc/agy070DOI Listing
January 2019
2 Reads

Research Protocol to Evaluate the Effects of Alcohol Policy Changes in Lithuania.

Alcohol Alcohol 2019 Jan;54(1):112-118

Clinic of Anaesthesiology and Intensive Care, Faculty of Medicine, Centre of Toxicology, Vilnius University, Šiltnamių st. 29, Vilnius, Lithuania.

Aims: To point out the importance for public health to evaluate the past policy changes (2016-2018) in Lithuania. To present a research protocol to conduct this evaluation.

Short Summary: The staggered implementation of key alcohol policies in Lithuania over the past two years offers the possibility to evaluate 'best buys' for alcohol policies for this country. Read More

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https://academic.oup.com/alcalc/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/alcalc/agy068DOI Listing
January 2019
14 Reads

Therapeutic Drug Monitoring of Naltrexone and 6β-Naltrexol During Anti-craving Treatment in Alcohol Dependence: Reference Ranges.

Alcohol Alcohol 2019 Jan;54(1):51-55

Department of Addictive Behaviour and Addiction Medicine, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Germany.

Aims: Aim of this study was to associate concentration of naltrexone and its major active metabolite 6β-naltrexol in blood with therapeutic outcome during treatment with naltrexone in subjects with alcohol dependence. Treatment with the μ-opiate receptor antagonist naltrexone has been shown to reduce craving for alcohol and alcohol intake in patients suffering from alcohol dependence.

Short Summary: This article shows the use of therapeutic drug monitoring in alcohol dependent patients, who are treated with naltrexone. Read More

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https://academic.oup.com/alcalc/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/alcalc/agy067DOI Listing
January 2019
4 Reads

New Alcohol Biomarkers. New challenges.

Alcohol Alcohol 2018 Nov;53(6):762-763

Psychiatry Department, Addictive Behaviors Unit, Clinic Hospital, Barcelona, Spain.

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https://academic.oup.com/alcalc/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/alcalc/agy064DOI Listing
November 2018
4 Reads

Integrated Treatment at the First Stage: Increasing Motivation for Alcohol Patients with Comorbid Disorders during Inpatient Detoxification.

Alcohol Alcohol 2018 Nov;53(6):719-727

Department of Clinical Psychology, University of Konstanz, Universitätsstr. 10, Konstanz, Germany.

Aims: Co-occurring mental disorders can complicate the detoxification treatment process and outcome. The aim of this study is to examine whether a brief psychoeducational group counseling session during detoxification treatment can increase the motivation for and utilization of subsequent treatments.

Short Summary: Interventions increased utilization of post-detoxification treatment and reduced alcohol-related readmissions. Read More

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http://dx.doi.org/10.1093/alcalc/agy066DOI Listing
November 2018
1 Read

Interaction Effects between the Cumulative Genetic Score and Psychosocial Stressor on Self-Reported Drinking Urge and Implicit Attentional Bias for Alcohol: A Human Laboratory Study.

Alcohol Alcohol 2019 Jan;54(1):30-37

Department of Psychology, Syracuse University, Syracuse, NY, USA.

Aims: The current candidate gene and environment interaction (cGxE) study examined whether the effects of an experimentally manipulated psychosocial stressor on self-reported drinking urge and implicit attentional bias for alcohol cues differ as a function of a cumulative genetic score of 5-HTTLPR, MAO-A, DRD4, DAT1 and DRD2 genotypes. The current study also examined whether salivary alpha-amylase level or self-reported anxiety state mediate these cGxE effects.

Short Summary: Individuals with high cumulative genetic risk score of the five monoamergic genotypes showed greater attentional bias toward alcohol cues when exposed to a psychosocial stressor than when not exposed. Read More

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https://academic.oup.com/alcalc/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/alcalc/agy065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324655PMC
January 2019
12 Reads

Alcohol Consumption and the Risk of Gastroesophageal Reflux Disease: A Systematic Review and Meta-analysis.

Alcohol Alcohol 2019 Jan;54(1):62-69

Department of Gastroenterology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.

Aims: Epidemiologic evidence on alcohol consumption increasing the risk of gastroesophageal reflux disease (GERD) is contradictory. This study aimed to investigate the correlation between alcohol consumption and GERD by a meta-analysis of observational studies.

Short Summary: Gastroesophageal reflux disease (GERD) is a prevalent disease, and the incidence is rising. Read More

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http://dx.doi.org/10.1093/alcalc/agy063DOI Listing
January 2019
2 Reads

Brief Intervention Among Mexican-Origin Young Adults in the Emergency Department at the USA-Mexico Border: Examining the Role of Patient's Preferred Language of Intervention in Predicting Drinking Outcomes.

Alcohol Alcohol 2018 Nov;53(6):728-734

Texas Tech University of Health Science Center, El Paso, TX, USA.

Aims: Determine if the language in which brief intervention (BI) is delivered influences drinking outcomes among Mexican-origin young adults in the emergency department when controlling for ethnic matching.

Short Summary: Aim of study was to determine if a patient's preferred language of intervention influences drinking outcomes among Mexican-origin young adults in the emergency department. Results indicate no significant differences in drinking outcomes among those who received BI in Spanish and BI in English. Read More

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http://dx.doi.org/10.1093/alcalc/agy060DOI Listing
November 2018
4 Reads

Fathers' Alcohol Consumption and Long-Term Risk for Mortality in Offspring.

Alcohol Alcohol 2018 Nov;53(6):753-759

Department of Public Health Sciences, Stockholm University, Stockholm, Sweden.

Aim: This study examined associations between fathers' alcohol consumption and risk for total and cause-specific mortality in offspring.

Short Summary: We examined the associations between fathers' alcohol consumption and total and cause-specific mortality in adult offspring. Fathers' alcohol consumption was associated with increased risk of alcohol-related mortality in offspring. Read More

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http://dx.doi.org/10.1093/alcalc/agy058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203123PMC
November 2018
2 Reads

Women's Self-Perceived Similarity to Their Mother and Associations with Patterns of Alcohol Misuse over 20 Years.

Alcohol Alcohol 2018 Nov;53(6):707-715

School of Nursing and Department of Psychiatry, Columbia University, New York City, New York.

Aims: This study examined transgenerational transmission of risk for female alcohol misuse. Women's perceived similarity to their mother/father in adulthood was examined in terms of its influence on the expected association between perceived maternal alcohol use and female offsprings' trajectories of alcohol misuse. We hypothesized that a daughter's self-perceived similarity to her mother, in instances where her mother was perceived to be a frequent- or problem-drinker, would be associated with an increase in the daughter's count of negative consequences from alcohol use and potential symptoms of alcohol dependence across adulthood. Read More

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http://dx.doi.org/10.1093/alcalc/agy059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203126PMC
November 2018
3 Reads

Distilled Spirits Overconsumption as the Most Important Factor of Excessive Adult Male Mortality in Europe.

Alcohol Alcohol 2018 Nov;53(6):742-752

Department of Risk Factor Prevention, Federal Research Institute for Health Organization and Informatics of Ministry of Health of the Russian Federation, 11 Dobrolyubova, Moscow, Russia.

Aims: To explain comprehensively variations in adult male mortality rate in Europe, and in particular, high mortality in some East European countries with particular focus on specific patterns of alcohol consumption.

Short Summary: Per capita distilled spirits consumption is found to be the strongest determinant of the adult male mortality rate in Europe as soon as the unrecorded alcohol consumption is taken into account. It turns out to be much stronger than the other tested significant determinants such as per capita health expenditures, smoking prevalence, consumption of hard drugs and per capita consumption of vegetables and fruit. Read More

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http://dx.doi.org/10.1093/alcalc/agy054DOI Listing
November 2018
3 Reads

Early Liver Transplantation is a Viable Treatment Option in Severe Acute Alcoholic Hepatitis.

Alcohol Alcohol 2018 Nov;53(6):716-718

Divison of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, CA, USA.

Liver transplantation is lifesaving for patients with severe acute alcoholic hepatitis (SAH) with preliminary data demonstrating favorable early post-transplant outcomes. Using the United Network for Organ Sharing database, we demonstrate that liver transplantation for SAH in the USA has steadily increased and is associated with similar 1- and 3-year post-transplant survival as well as comparable 30-day waitlist mortality to acute liver failure due to drug-induced liver injury. Read More

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http://dx.doi.org/10.1093/alcalc/agy056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203122PMC
November 2018
4 Reads
2.890 Impact Factor

Alcoholic beverages and cancer: raising the alarm.

Authors:
Gianni Testino

Alcohol Alcohol 2018 Nov;53(6):761-763

Alcohological Regional Centre - Liguria Region, ASL3 Genovese c/o Ospedale Policlinico San Martino, Padiglione 10 (ground floor), Piazzale R. Benzi 10, Genova, Italy.

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http://dx.doi.org/10.1093/alcalc/agy057DOI Listing
November 2018
7 Reads

Quantifying the Nature and Extent of Children's Real-time Exposure to Alcohol Marketing in Their Everyday Lives Using Wearable Cameras: Children's Exposure via a Range of Media in a Range of Key Places.

Alcohol Alcohol 2018 Sep;53(5):626-633

National Institute for Health Innovation, University of Auckland, 261 Morrin Road, Glen Innes, Auckland, New Zealand.

Aims: Children's exposure to alcohol marketing is typically measured using self-report data, television viewing data or street marketing audits, which are subject to bias and often do not provide quantifiable measures of daily exposure. This article describes an innovative methodology to capture the world in which children live using wearable cameras.

Short Summary: Children wearing wearable cameras were exposed 4. Read More

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http://dx.doi.org/10.1093/alcalc/agy053DOI Listing
September 2018
2 Reads

Can the Impact of Topiramate on Memory Processes be Related to Its 'Antialcoholic Activity'?-A Preclinical Study.

Alcohol Alcohol 2018 Nov;53(6):688-698

Department of Pharmacodynamics, Medical University of Lódz, Muszynskiego 1, 90-151 Lódz, Poland.

Aims: Topiramate causes the inhibition of alcohol consumption in addicts but the mechanism of this action has not been fully understood yet. Nowadays, it seems that memory may have a role in the development of dependence. In this study, the impact of topiramate and ethanol on the bioelectric activity of the brain in rabbits and on spatial memory in rats was evaluated. Read More

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http://dx.doi.org/10.1093/alcalc/agy052DOI Listing
November 2018
4 Reads

P3 Component as a Potential Endophenotype for Control Inhibition in Offspring of Alcoholics.

Alcohol Alcohol 2018 Nov;53(6):699-706

Department of Psychiatry, Research Institute 12 de Octubre (i + 12), Madrid, Spain.

Aims: To assess inhibitory processes and the ongoing event-related potential (ERP) activity of offspring of alcoholics (OA) during a Go/No-Go task, with the purpose of characterizing possible psychophysiological endophenotypes for alcohol-dependent vulnerability.

Short Summary: EEG recordings and ERP measurements of young adults with positive and negative family history of alcoholism where obtained while they performed a Go/No-Go task to assess inhibitory processes. Offspring of alcoholics showed a different ERP pattern compared to the control group and exerted greater effort than the control group. Read More

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http://dx.doi.org/10.1093/alcalc/agy051DOI Listing
November 2018
19 Reads

Identifying and Characterizing Subpopulations of Heavy Alcohol Drinkers Via a Sucrose Preference Test: A Sweet Road to a Better Phenotypic Characterization?

Alcohol Alcohol 2018 Sep;53(5):560-569

Section on Clinical Psychoneuroendocrinology and Neuropsychopharmacology, National Institute on Alcohol Abuse and Alcoholism and National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD, USA.

Aims: Sweet preference in individuals with alcohol use disorder (AUD) has been associated with family history of AUD and personality traits. Therefore, testing sweet preference may help identify subpopulations of AUD individuals.

Short Summary: Sweet preference has been associated with family history of AUD and personality traits. Read More

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http://dx.doi.org/10.1093/alcalc/agy048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104622PMC
September 2018
11 Reads

The Dangerous Pattern of Concurrent Use of Alcohol and Cocaine Among Drunk-Drivers of Northeast Italy.

Alcohol Alcohol 2018 Nov;53(6):735-741

Department of Legal and Occupational Medicine, Toxicology and Public Health, University-Hospital of Padova, Padua, Italy.

Aim: To estimate the prevalence of drug and polydrug use among drunk-drivers during the driving license regranting program, in order to assess the inclusion of toxicological tests on hair and urine samples in the systematic methodology in this category of subjects.

Short Summary: A total of 2160 drunk-drivers were tested for alcohol and drugs during driving license regranting. Thirty-one subjects showed alcohol use, 212 illicit drug use and, among these, 131 were polydrug users. Read More

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http://dx.doi.org/10.1093/alcalc/agy050DOI Listing
November 2018
4 Reads

Maladaptive Schemas Among People Addicted to Alcohol: Heterogeneity but not Specificity?

Alcohol Alcohol 2018 Nov;53(6):682-687

Department of Health Psychology, Institute of Clinical Psychology, SWPS University of Social Sciences and Humanities, Chodakowska 19/31, Room N314, Warsaw, Poland.

Aims: Early maladaptive schemas described by Young theoretically underlie the development of psychopathology, including substance use. The key assumption is that the schemas do not act in isolation but create configurations that are, at least to a certain extent, distinctive for specific disorders. Thus, the aim of the current study was to examine whether a schema profile specific to alcohol addiction can be identified when compared to profiles obtained from a non-clinical sample. Read More

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http://dx.doi.org/10.1093/alcalc/agy047DOI Listing
November 2018
6 Reads

Interactions between TLR4 methylation and alcohol consumption on subjective responses to an alcohol infusion.

Alcohol Alcohol 2018 Nov;53(6):650-658

Department of Psychology and Neuroscience, University of Colorado Boulder, UCB 344, Boulder, CO, USA.

Aims: Converging evidence has implicated perturbed inflammatory signaling in alcohol use disorders (AUDs), and both animal and human studies suggest that alcohol-induced inflammatory signaling is mediated by Toll-Like Receptor 4 (TLR4). We previously demonstrated that TLR4 is hypermethylated in subjects with AUD compared to control individuals. Examining the relationship between TLR4 methylation and subjective alcohol responses could shed light on the role of TLR4 in promoting AUDs, thereby highlighting its potential as a treatment target. Read More

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http://dx.doi.org/10.1093/alcalc/agy046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203129PMC
November 2018
13 Reads

Sex Differences in the Association between Heavy Drinking and Behavioral Distress Tolerance and Emotional Reactivity Among Non-Depressed College Students.

Alcohol Alcohol 2018 Nov;53(6):674-681

Department of Psychiatry, Harvard Medical School, Boston, MA, USA.

Background: Heavy episodic drinking (HED) is a common behavior among college students that is associated with severe negative consequences. Negative reinforcement processes have been applied to elucidate mechanisms underlying relationships between consumption of alcohol and the desire to alleviate negative feelings. Distress tolerance (DT) and emotional reactivity are two mechanisms that are consistent with the self-medication model that may contribute to HED. Read More

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http://dx.doi.org/10.1093/alcalc/agy045DOI Listing
November 2018
8 Reads

Chinese Women's Drinking Patterns Before and After the Hong Kong Alcohol Policy Changes.

Alcohol Alcohol 2018 Jul;53(4):477-486

The School of Public Health & Primary Care, The Chinese University of Hong Kong, Prince of Wales Hospital, New Territories, Hong Kong SAR.

Aims: To examine the patterns of alcohol consumption in Hong Kong Chinese women before and after a period of major alcohol policy amendments.

Short Summary: This study compared alcohol consumption patterns in Hong Kong Chinese women before and after a period of major alcohol policy amendments and found increased drinking among certain subgroups, particularly middle-aged women. These increases are likely due to personal factors (e. Read More

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http://dx.doi.org/10.1093/alcalc/agy010DOI Listing
July 2018
7 Reads

Association of Biological Markers of Alcohol Consumption and Self-Reported Drinking with Hippocampal Volume in a Population-Based Sample of Adults.

Alcohol Alcohol 2018 Sep;53(5):539-547

Department of Psychiatry, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd. Dallas, TX, USA.

Aims: The current study examined a large community cohort to understand relationships between indicators of alcohol consumption and hippocampal volume.

Short Summary: Alcohol use measures were not associated with hippocampal volume in a population-based sample. However, alcohol consumption was associated with hippocampal volume reduction in subsets of the sample including subjects aged ≥50 years old, and those with none to moderate levels of depressive symptoms. Read More

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http://dx.doi.org/10.1093/alcalc/agy041DOI Listing
September 2018
15 Reads

Selective Blockade of T-Type Ca2+ Channels is Protective Against Alcohol-Withdrawal Induced Seizure and Mortality.

Alcohol Alcohol 2018 Sep;53(5):526-531

Department of Neurobiology and Anatomy, Wake Forest University School of Medicine, 1 Medical Center Boulevard, Winston-Salem, NC, USA.

Aims: We have previously demonstrated that blockade of T-type calcium channels by the non-selective antagonist, ethosuximide (ETX), is effective at reducing electrographical and behavioral correlates of alcohol-withdrawal (WD) seizure. Here, we investigated whether blockade of these calcium channels with the selective antagonist TTA-P2 also reduces alcohol-WD seizure.

Short Summary: The non-specific T-type calcium channel antagonist, ETX, is protective against alcohol-WD seizure. Read More

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http://dx.doi.org/10.1093/alcalc/agy042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104618PMC
September 2018
5 Reads