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    PNPLA3 Association with Alcoholic Liver Disease in a Cohort of Heavy Drinkers.
    Alcohol Alcohol 2018 Feb 21. Epub 2018 Feb 21.
    Department of Psychiatry and Psychology, Mayo Clinic, 2nd Street SW, Rochester, MN 55905, USA.
    Aims: Prior studies have established variation at the PNPLA3gene to be associated with a risk of developing alcoholic liver disease (ALD). We attempt to replicate this finding and other potential genetic variations previously associated with ALD utilizing a case-control design in a cohort of subjects with alcohol use disorders.

    Short Summary: This case-control study performed in a US clinical sample of heavy drinkers, replicates the previously reported association between ALD and rs738409 polymorphism in the PNPLA3gene in heavy drinkers. Read More

    Survey Estimates of Changes in Alcohol Use Patterns Following the 2012 Privatization of the Washington Liquor Monopoly.
    Alcohol Alcohol 2018 Feb 8. Epub 2018 Feb 8.
    Alcohol Research Group, Public Health Institute, 6001 Shellmound Ave, Suite 450, Emeryville, CA 94608, USA.
    Aims: The US state of Washington's 333 state-run liquor stores were privatized on 1 June 2012 and purchases began in ~1500 licensed stores of a variety of types. A regime of taxes and fees was implemented to replace the revenues generated by the state stores and, 1 year later, the beer tax was reduced by two thirds. This study evaluates the impact of these changes on total alcohol and spirits consumption in a retrospective pre-test design. Read More

    Association Analysis Between Genetic Variation in GATA Binding Protein 4 (GATA4) and Alcohol Use Disorder.
    Alcohol Alcohol 2018 Feb 5. Epub 2018 Feb 5.
    Section on Clinical Genomics and Experimental Therapeutics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, 10 Center Drive (10CRC), Bethesda, MD 20892, USA.
    Aims: Previous genetic association studies have shown that variation in the GATA4 gene encoding the GATA binding protein 4, a binding protein that binds to the ANA sequence GATA, increase susceptibility for alcohol use disorder (AUD). In this study, we aimed to replicate those findings in an independent sample and analyze their association with anxiety.

    Methods: Overall, 1044 individuals with AUD [534 European American (EA), 510 African Americans (AA)] and 645 controls [413 EA, 232 AA] were genotyped using 34 markers. Read More

    Patient Satisfaction as a Moderator of Risky Alcohol Consumers' Attitude Towards Screening and Brief Intervention: A Cross Sectional Survey.
    Alcohol Alcohol 2018 Jan 25. Epub 2018 Jan 25.
    Medical Faculty, Institute for General Practice and Family Medicine,University of Halle-Wittenberg, Magdeburger Str. 8, 06112 Halle/Saale, Germany.
    Aims: Although shown to be effective, General Practitioners (GPs) tend to refuse the implementation of Screening and Brief Intervention (SBI). Their expectation of negative response by patients seems to contrast with the positive attitude towards SBI of these patients. This discrepancy may be resolved by regarding moderators such as drinking status and patient satisfaction. Read More

    Living Donor Liver Transplantation for Alcoholic Liver Disease.
    Alcohol Alcohol 2018 Jan 23. Epub 2018 Jan 23.
    Department of Surgery, University of California, San Francisco, Box 0780, 505 Parnassus Avenue, M884, San Francisco, CA 94117, USA.
    Aims: Alcoholic liver disease (ALD) is now a well-recognized indication for liver transplantation. This paper reviews existing literature on living donor liver transplantation (LDLT) for ALD and presents data from a single, high volume United States liver transplant center.

    Methods: For the literature review, a PubMed search was undertaken using the search terms 'living donor' and 'alcoholic liver disease'. Read More

    Transplanting Patients with Alcohol-related Liver Disease in the National Health System: New Rules and Decisions.
    Alcohol Alcohol 2018 Jan 23. Epub 2018 Jan 23.
    Clinical Director of Hepatology and Liver Transplantation, The Liver Unit, Nuffield House, Queen Elizabeth Hospital, Mindelsohn Way, Birmingham B15 2GW, UK.
    Aims: The UK has a socialized healthcare system that provides treatment that is free at the point of care for acute and chronic health disorders (the National Health Service-NHS), which is currently experiencing a period of unprecedented challenge.

    Methods: A narrative review that discusses present and future arrangements for transplantation of alcohol-related liver disease (ArLD) in the UK.

    Results: Liver disease in the UK is reaching epidemic proportions due to obesity and metabolic disease compounding alcohol-mediated liver damage. Read More

    Alcohol Content in the 'Hyper-Reality' MTV Show 'Geordie Shore'.
    Alcohol Alcohol 2018 Jan 21. Epub 2018 Jan 21.
    UK Centre for Tobacco and Alcohol Studies, Department for Health, University of Bath, 1 W 5.124, Calverton Down, Bath BA2 7AY, UK.
    Aim: To quantify the occurrence of alcohol content, including alcohol branding, in the popular primetime television UK Reality TV show 'Geordie Shore' Series 11.

    Methods: A 1-min interval coding content analysis of alcohol content in the entire DVD Series 11 of 'Geordie Shore' (10 episodes). Occurrence of alcohol use, implied use, other alcohol reference/paraphernalia or branding was recorded. Read More

    Self-Reported Knowledge, Correct Knowledge and use of UK Drinking Guidelines Among a Representative Sample of the English Population.
    Alcohol Alcohol 2018 Jan 17. Epub 2018 Jan 17.
    ScHARR, University of Sheffield, Regent Court, 30 Regent Street, Sheffield, S1 4DA, UK.
    Aims: Promotion of lower risk drinking guidelines is a commonly used public health intervention with various purposes, including communicating alcohol consumption risks, informing drinkers' decision-making and, potentially, changing behaviour. UK drinking guidelines were revised in 2016. To inform potential promotion of the new guidelines, we aimed to examine public knowledge and use of the previous drinking guidelines, including by population subgroup. Read More

    Commentary on 'Communicating Messages About Drinking': Using the 'Big Legal Guns' to Block Alcohol Health Warning Labels.
    Alcohol Alcohol 2018 Jan 16. Epub 2018 Jan 16.
    Centre for Alcohol Policy Research, La Trobe University, Plenty Road, Bundoora, Melbourne, Victoria 3086, Australia.
    Like the tobacco industry, the alcohol industry, with the support of governments in alcohol exporting nations, is looking to international trade and investment law as a means to oppose health warning labels on alcohol. The threat of such litigation, let alone its commencement, has the potential to deter all but the most resolute governments from implementing health warning labeling. Read More

    Changing Collective Social Norms in Favour of Reduced Harmful Use of Alcohol: A Review of Reviews.
    Alcohol Alcohol 2018 Jan 16. Epub 2018 Jan 16.
    Institute for Mental Health Policy Research, CAMH, 33 Russell Street, Toronto, Ontario, Canada M5S 2S1.
    Background: Public sector bodies have called for policies and programmes to shift collective social norms in disfavour of the harmful use of alcohol. This article aims to identify and summarize the evidence and propose how policies and programmes to shift social norms could be implemented and evaluated.

    Design: Review of reviews for all years to July 2017. Read More

    Treatment for Alcohol Dependence in Primary Care Compared to Outpatient Specialist Treatment-A Randomized Controlled Trial.
    Alcohol Alcohol 2018 Jan 16. Epub 2018 Jan 16.
    Department of Public Health Sciences, Karolinska Institutet, Centre for Psychiatry Research, Stockholm Health Care Services, Riddargatan 1, Mottagningen för alkohol och hälsa, Riddargatan 1, 11435 Stockholm, Sweden.
    Aim: To investigate if treatment for alcohol dependence in primary care is as effective as specialist addiction care.

    Method: Randomized controlled non-inferiority trial, between groups parallel design, not blinded. The non-inferiority limit was set to 50 grams of alcohol per week. Read More

    Proscriptive vs. Prescriptive Health Recommendations to Drink Alcohol Within Recommended Limits: Effects on Moral Norms, Reactance, Attitudes, Intentions and Behaviour Change.
    Alcohol Alcohol 2018 Jan 10. Epub 2018 Jan 10.
    Department of Psychology and Counselling, Bishop Otter Campus, College Lane, Chichester PO19 6PE, UK.
    Aims: Health advice can be framed in terms of prescriptive rules (what people should do, e.g. you should drink alcohol within recommended limits) or proscriptive rules (what people should not do, e. Read More

    Effects of Alcohol Cues on MRS Glutamate Levels in the Anterior Cingulate.
    Alcohol Alcohol 2018 Jan 10. Epub 2018 Jan 10.
    Psychological and Brain Sciences, Indiana University, Bloomington, IN, USA.
    Growing evidence suggests that glutamate neurotransmission plays a critical role in alcohol addiction. Cue-induced change of glutamate has been observed in animal studies but never been investigated in humans. This work investigates cue-induced change in forebrain glutamate in individuals with alcohol use disorder (AUD). Read More

    Judgement of Breath Alcohol Concentration Levels Among Pedestrians in the Night-Time Economy-A Street-Intercept Field Study.
    Alcohol Alcohol 2018 Jan 10. Epub 2018 Jan 10.
    School of Psychology, Faculty of Health, Deakin University Geelong, Locked Bag 20001, Geelong, Victoria 3220, Australia.
    Aims: To evaluate how well people in the night-time economy can assess their own breath alcohol concentration (BrAC), in the context of a change in breath alcohol limits for driving.

    Methods: We conducted a field study of 242 participants over 5 nights in the central business district of a university town in New Zealand. Participants completed a short survey, which included questions on their self-reported level of intoxication and the self-estimated BrAC. Read More

    Co-existing Hepatitis C and Alcoholic Liver Disease: A Diminishing Indication for Liver Transplantation?
    Alcohol Alcohol 2018 Jan 10. Epub 2018 Jan 10.
    Department of Internal Medicine, Section of Hepatology, Division of Gastroenterology and Hepatology, School of Medicine, University of Colorado Denver, 1635 Aurora Court, B1-54, Aurora, CO 80045, USA.
    Aims: To provide an overview of published literature on the interaction of alcohol and hepatitis C virus (HCV) in the accelerated progression of liver disease to cirrhosis as relates to decision-making for the management of the liver transplant candidate and recipient.

    Methods: General PubMed search was employed along with expert input to identify the relevant articles on the topic. The authors also utilized both backward and forward citation review of the relevant articles and reviews to identify articles on identified topic. Read More

    Alcohol Use in Adolescence and Later Working Memory: Findings From a Large Population-Based Birth Cohort.
    Alcohol Alcohol 2018 Jan 10. Epub 2018 Jan 10.
    School of Experimental Psychology, University of Bristol, Priory Road, Bristol, BS8 1TU, UK.
    Aims: The study aimed to examine the association between adolescent alcohol use and working memory (WM) using a large population sample.

    Methods: Data from the Avon Longitudinal Study of Parents and Children were used to investigate the association between alcohol use at age 15 years and WM 3 years later, assessed using the N-back task (N ~ 3300). A three-category ordinal variable captured mutually exclusive alcohol groupings ranging in order of severity (i. Read More

    A Formative Evaluation of Two FASD Prevention Communication Strategies.
    Alcohol Alcohol 2018 Jan 10. Epub 2018 Jan 10.
    Institute for Circumpolar Health Studies, College of Health at the University of Alaska Anchorage, 1901 Bragaw Street, Suite 270, Anchorage, AK 99508, USA.
    Aims: To evaluate the feasibility, acceptability and effectiveness of placing FASD prevention messages in the women's restrooms of establishments serving alcohol in Alaska and the Yukon, regions with high rates of FASD.

    Methods: Our team placed an FASD educational poster, and posters affixed to a pregnancy test dispenser, in women's restrooms of bars and restaurants. We compared drinking behaviors and knowledge and beliefs about FASD among participants at baseline and at follow-up. Read More

    Effectiveness of Mass Media Campaigns to Reduce Alcohol Consumption and Harm: A Systematic Review.
    Alcohol Alcohol 2018 Jan 10. Epub 2018 Jan 10.
    Division of Epidemiology and Public Health, University of Nottingham, Nottingham, UK.
    Aims: To assess the effectiveness of mass media messages to reduce alcohol consumption and related harms using a systematic literature review.

    Methods: Eight databases were searched along with reference lists of eligible studies. Studies of any design in any country were included, provided that they evaluated a mass media intervention targeting alcohol consumption or related behavioural, social cognitive or clinical outcomes. Read More

    Role of TLR4 in the Modulation of Central Amygdala GABA Transmission by CRF Following Restraint Stress.
    Alcohol Alcohol 2018 Jan 4. Epub 2018 Jan 4.
    Department of Neuroscience, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
    Aims: Stress induces neuroimmune responses via Toll-like receptor 4 (TLR4) activation. Here, we investigated the role of TLR4 in the effects of the stress peptide corticotropin-releasing factor (CRF) on GABAergic transmission in the central nucleus of the amygdala (CeA) following restraint stress.

    Methods: Tlr4 knock out (KO) and wild-type rats were exposed to no stress (naïve), a single restraint stress (1 h) or repeated restraint stress (1 h per day for 3 consecutive days). Read More

    Insula Sensitivity to Unfairness in Alcohol Use Disorder.
    Alcohol Alcohol 2018 Jan 4. Epub 2018 Jan 4.
    Department of Clinical and Experimental Medicine, Center for Social and Affective Neuroscience,Linköping University, Linköping, Sweden.
    Aims: Social decision making has recently been evaluated in alcohol use disorder (AUD) using the ultimatum game (UG) task, suggesting a possible deficit in aversive emotion regulation elicited by the unfairness during this task. Despite the relevance to relapse of this possible faulty regulation, the brain correlates of the UG in AUD are unknown.

    Methods: In total, 23 AUD and 27 healthy controls (HC) played three consecutive fMRI runs of the UG, while behavioral and brain responses were recorded. Read More

    The Effect of Brief Interventions for Alcohol Among People with Comorbid Mental Health Conditions: A Systematic Review of Randomized Trials and Narrative Synthesis.
    Alcohol Alcohol 2017 Dec 26. Epub 2017 Dec 26.
    Centre for Implementation Science, Health Service and Population Research Department, Centre for Implementation Science, Institute of Psychiatry, Psychology & Neuroscience, King's College London, 16 De Crespigny Park, London SE5 8AF, UK.
    Aims: To review the evidence on the effect of brief interventions (BIs) for alcohol among adults with risky alcohol consumption and comorbid mental health conditions.

    Methods: A systematic review of randomized controlled trials (RCTs) published before May 2016 was undertaken and reported according to PRISMA guidelines. The findings were combined in a narrative synthesis. Read More

    Post-transplant Outcomes of Persons Receiving a Liver Graft for Alcoholic Liver Disease.
    Alcohol Alcohol 2017 Dec 26. Epub 2017 Dec 26.
    Department of Surgery, University of Pittsburgh School of Medicine, UPMC Presbyterian, 200 Lothrop Street, Pittsburgh, PA 15213, USA.
    Aims: Liver transplantation (LT) for alcoholic liver disease (ALD) remains controversial yet following transplantation outcomes for patients with this disease are generally similar to patients transplanted for other types of liver diseases.

    Methods: In this review, we cover critical literature of ALD LT including established and recent findings of medical and psychosocial outcomes for ALD patients and compare their outcomes to other liver transplant recipients where evidence exists.

    Results: Overall medical and psychosocial outcomes for ALD LT recipients compare favorably to patients transplanted for other types of liver diseases. Read More

    The Influence of Alcohol Use on Outcomes in Patients Transplanted for Non-alcoholic Liver Disease.
    Alcohol Alcohol 2017 Dec 21. Epub 2017 Dec 21.
    Liver Transplantation Unit, Digestive Department, Saint Eloi University Hospital, University of Montpellier, 34295 Montpellier Cedex 5, France.
    Alcohol relapse after liver transplantation (LT) for alcoholic liver disease (ALD) is a common event that has been extensively studied. In contrast, alcohol consumption has usually been neglected in patients transplanted for other liver diseases. First off, patients can be mislabeled as 'non-ALD' when they suffer from another chronic liver disease. Read More

    Symptom-Triggered Detoxification Using the Alcohol-Withdrawal-Scale Reduces Risks and Healthcare Costs.
    Alcohol Alcohol 2018 Jan;53(1):71-77
    University Hospital of Psychiatry, University of Bern, Switzerland.
    Aims: As there are only a few existing experimental studies on symptom-triggered therapy for patients with alcohol withdrawal, we investigated the effectiveness of symptom-triggered detoxification regarding the use and dosage of benzodiazepine and withdrawal complications in a naturalistic clinical setting of a specialized treatment center for alcohol use disorder.

    Methods: In total, 301 charts of patients who entered residential treatment for alcohol withdrawal were included in the retrospective analysis. Charts of 176 patients treated with the Alcohol Withdrawal-Scale (AWS) were compared to the charts of 125 patients treated with treatment as usual (TAU) before the implementation of AWS. Read More

    Cross-Cultural Adaptation and Psychometric Properties of the AUDIT and CAGE Questionnaires in Tanzanian Swahili for a Traumatic Brain Injury Population.
    Alcohol Alcohol 2018 Jan;53(1):112-120
    Duke Division of Emergency Medicine, Department of Surgery, Duke University Medical Center, 2301 Erwin Road, Durham, North Carolina, 27710, USA.
    Aims: To develop Swahili versions of the Alcohol Use Disorders Identification Test (AUDIT) and CAGE questionnaires and evaluate their psychometric properties in a traumatic brain injury (TBI) population in Tanzania.

    Methods: Swahili versions of the AUDIT and CAGE were developed through translation and back-translation by a panel of native speakers of both English and Swahili. The translated instruments were administered to a sample of Tanzanian adults from a TBI registry. Read More

    Central Administration of Cyclosporine A Decreases Ethanol Drinking.
    Alcohol Alcohol 2017 Dec 21. Epub 2017 Dec 21.
    Laboratory for Clinical and Translational Research in Psychiatry, Research Service and Psychiatry, Denver VA Medical Center, 1050 Clermont Street, Denver, CO 80220-0116, USA.
    Aims: Abstinence among alcohol dependent liver graft recipients is remarkably high. The routine use of anti-immune agents in these patients led to rodent studies showing that immunosuppressants acting through inhibition of calcineurin (CLN) are highly effective in decreasing alcohol consumption. It remained unclear, however, whether the decreased alcohol consumption in rodent models is mediated through peripheral suppression of immune response or centrally through direct inhibition of cyclophilin-CLN in the brain. Read More

    Comparing and Combining Topiramate and Aripiprazole on Alcohol-Related Outcomes in a Human Laboratory Study.
    Alcohol Alcohol 2017 Dec 21. Epub 2017 Dec 21.
    Center for Alcohol and Addiction Studies, Department of Psychiatry and Human Behavior, Brown University, 121 South Main Street, Providence, RI 02912, USA.
    Aims: The goal of this study was to evaluate the efficacy of topiramate up to 200 mg/day and of aripiprazole up to 15 mg/day, alone and combined, in reducing alcohol-related outcomes in a human laboratory study.

    Method: This was a 5 week, between-subject, double-blind, placebo-controlled human laboratory study with topiramate [0 mg/day (placebo), 100 mg/day, 200 mg/day] and aripiprazole [0 mg/day (placebo), 7.5 mg/day, 15 mg/day] in 90 non-treatment seeking, heavy drinking, alcohol-dependent individuals. Read More

    Cancer and Alcohol Consumption in People Aged 50 Years or More in Europe.
    Alcohol Alcohol 2017 Dec 19. Epub 2017 Dec 19.
    Agència de Salut Pública de Barcelona, Plaça Lesseps 1, 08023 Barcelona, Spain.
    Aims: To estimate the prevalence of hazardous drinking in individuals aged 50 and older who had or had had cancer in 17 European countries and Israel and to analyze the factors associated with their consumption.

    Methods: Cross-sectional study based on data from 2011 to 2013 SHARE surveys. A total of 69,509 individuals aged 50 or more from 17 European countries and Israel participated in the study. Read More

    Patterns of Alcohol Use in Italian Emerging Adults: A Latent Class Analysis Study.
    Alcohol Alcohol 2017 Dec 11. Epub 2017 Dec 11.
    Department of Psychology,Università Cattolica del Sacro Cuore, Largo Gemelli 1, 20123 Milano, Italy.
    Aims: The goals of the current study were to identify latent classes of alcohol users among Italian emerging adults (18-33 years), examine differences in the class solution based on socio-demographic characteristics, and examine whether differences exist across classes in experiencing different types of alcohol-related negative consequences.

    Methods: Participants (N = 5955; 62.72% female; mean age 27. Read More

    Transplantation for Alcohol-related Liver Disease: Is It Fair?
    Alcohol Alcohol 2017 Dec 11. Epub 2017 Dec 11.
    Division of Gastroenterology and Transplantation Institute, Loma Linda University Medical, Loma Linda University Health, 25865 Barton Road, Suite 101, Loma Linda, CA 92354, USA.
    Aims: Alcohol-related liver disease (ALD) is the second leading cause of liver transplantation performed in the USA and Europe. We aimed to provide a narrative review of the major ethical issues governing transplantation for ALD.

    Methods: We performed a narrative review of the ethical concepts in organ allocation for ALD, including alcoholic hepatitis. Read More

    TAQ1A1 Allele of the DRD2 Gene Region Contribute to Shorter Survival Time in Alcohol Dependent Individuals When Controlling for the Influence of Age and Gender. A Follow-up Study of 18 Years.
    Alcohol Alcohol 2017 Dec 11. Epub 2017 Dec 11.
    Department of Psychology, University of Gothenburg, PO Box 500, SE-405 30 Göteborg, Sweden.
    Aims: To investigate the influence of the A1 allele of the TAQ1A polymorphism in the dopamine D2 receptor (DRD2) gene region on mortality in adult individuals with alcohol dependence.

    Methods: The study sample consisted of 359 alcohol-dependent individuals treated for severe alcohol withdrawal symptoms in 1997. Years of survival was studied in an 18-year follow-up. Read More

    Towards Standardizing the Alcoholism Evaluation Of Potential Liver Transplant Recipients.
    Alcohol Alcohol 2017 Dec 4:1-10. Epub 2017 Dec 4.
    Division of Gastroenterology and Hepatology, University of Wisconsin School of Medicine and Public Health, 600 Highland Ave, Madison, WI 53792, USA.
    Aims: For teams around the world, alcoholic liver disease patients comprise the largest, and clinically most controversial, group applying for liver transplant. And yet evaluation decisions for them remain highly variable by locale.

    Methods: Targeting standardized assessment, we provide guidelines on what information the transplant team should seek, from what sources, and how best to make use of it. Read More

    Susceptibility to Alcohol Hangovers: Not Just a Matter of Being Resilient.
    Alcohol Alcohol 2017 Dec 4:1-4. Epub 2017 Dec 4.
    Division of Pharmacology, Utrecht University, Universiteitsweg 99, 34584CG, Utrecht, The Netherlands.
    Introduction: Although most drinkers have experienced a hangover the day following heavy alcohol consumption, a minority claims to be hangover resistant despite consuming the same large quantities of alcohol as those reporting alcohol hangover. The aim of the current study was to examine if susceptibility to experiencing hangovers is related to a drinker's interpretation of wellbeing and psychological assets to bounce back.

    Methods: A survey was conducted among 2295 Dutch students assessing their past month alcohol consumption patterns, and measuring mental resilience and wellbeing. Read More

    Liver Transplantation in Patients with Alcoholic Liver Disease: A Retrospective Study.
    Alcohol Alcohol 2017 Dec 1:1-6. Epub 2017 Dec 1.
    Department of Internal Medicine, Gastroenterology and Hepatology, Catholic University of the Sacred Heart, Foundation A. Gemelli Hospital, Largo Gemelli 8, 00168 Rome, Italy.
    Aim: Alcoholic liver disease (ALD) is the most common liver disease in the Western World. Liver transplantation (LT) is the treatment for end-stage ALD. However, many transplant centers are still reluctant to transplant these patients because of the risk of alcohol relapse, recurrence of the primary liver disease and associated post-transplant complications. Read More

    Alcohol Relapse After Liver Transplantation for Alcoholic Cirrhosis-Impact on Liver Graft and Patient Survival: A Meta-analysis.
    Alcohol Alcohol 2017 Nov 29:1-7. Epub 2017 Nov 29.
    Department of Medicine, Division of Gastroenterology and Hepatology, University of Alabama at Birmingham, Birmingham, AL 35294-0012, USA.
    Aim: We performed meta-analysis to determine effect of alcohol relapse after liver transplantation (LT) for alcoholic cirrhosis on graft histology and survival.

    Methods: Studies were selected using following criteria: (a) LT for alcoholic cirrhosis, (b) reporting data on liver histology and/or patient survival among relapsers and abstainers, (c) minimum follow-up of 3 years. Random effects model was used to pool data to compare relapsers and abstainers on liver histology and patient survival. Read More

    A National Survey of Assertive Outreach Treatment Services for People Who Frequently Attend Hospital due to Alcohol-Related Reasons in England.
    Alcohol Alcohol 2017 Nov 22:1-5. Epub 2017 Nov 22.
    Addictions Department, National Addiction Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, 4 Windsor Walk, London SE58BB, UK.
    Aims: To characterize England's alcohol assertive outreach treatment (AAOT) services for people who frequently attend hospital due to alcohol-related reasons according to their concordance with six core AAOT components.

    Methods: A cross-sectional national survey using structured telephone interviews with health professionals examining 6 essential AAOT components. High-level AAOT services were those that delivered 5 or more components, mid-level 3 to 4 components, low-level AAOT services 2 or less. Read More

    Population Level Effects of a Mass Media Alcohol and Breast Cancer Campaign: A Cross-Sectional Pre-Intervention and Post-Intervention Evaluation.
    Alcohol Alcohol 2018 Jan;53(1):31-38
    School of Health & Social Care, Teesside University, Middlesbrough, Tees Valley TS1 3BX, UK.
    Aims: To examine the relationship between a TV-led breast cancer mass-media campaign in the North East of England (conducted in two waves: Jul/2015 and Nov/2015), awareness of the link between alcohol and cancer, intention to reduce alcohol consumption and support for alcohol related policies.

    Methods: Three cross-sectional surveys were conducted; one over the 2 weeks pre-campaign (n = 572); one immediately following campaign wave 1 (n = 576); and another immediately following campaign wave 2 (n = 552). Survey questions assessed; campaign exposure; awareness of the links between alcohol and related cancers; intention to change alcohol consumption; and support for alcohol related policies. Read More

    Craving as a DSM-5 Symptom of Alcohol Use Disorder in Non-Treatment Seekers.
    Alcohol Alcohol 2017 Nov 14:1-6. Epub 2017 Nov 14.
    Department of Psychology, University of California, Los Angeles, 1285 Franz Hall, Box 951563, CA 900951563, USA.
    Aims: DSM-5 has added craving as a new criterion and changed the diagnostic structure of alcohol use disorder (AUD). Though craving has long been a target of intervention, less is known about the impact this addition will have on prevalence and factor structure of AUD, particularly in non-treatment seeker with alcohol problems.

    Methods: Non-treatment seeking individuals reporting alcohol-related problems (N = 296) completed a structured clinical interview and the Penn Alcohol Craving Scale (PACS). Read More

    Prenatal Alcohol Exposure and Suspected Hearing Impairment Among Children: A Population-based Retrospective Cohort Study.
    Alcohol Alcohol 2017 Nov 14:1-7. Epub 2017 Nov 14.
    Department of Pharmacoepidemiology, Graduate School of Medicine and Public Health, Kyoto University, Yoshidakonoe-cho, Sakyo-ku, Kyoto 606-8501, Japan.
    Aims: This study aimed to examine the association between prenatal alcohol exposure and hearing impairment among Japanese children using early childhood health check-up data.

    Methods: This retrospective cohort study used population-based health check-up data for children who were born between April 2000 and March 2013 in Hofu city, Japan. Logistic regression models were used to evaluate the association between prenatal alcohol exposure and hearing impairment among children at the age of 36 months. Read More

    Treatment of Alcohol-Induced Psychotic Disorder (Alcoholic Hallucinosis)-A Systematic Review.
    Alcohol Alcohol 2017 Nov 14:1-9. Epub 2017 Nov 14.
    Betsi Cadwaladr University Health Board (BCUHB), Heddfan Unit, Wrexham Maelor Hospital, Wrexham, Wales LL13 7TD, UK.
    Aims: To evaluate the effectiveness of evidence based treatments for alcohol-induced psychotic disorder (AIPD) as described by ICD-10 and DSM-5, a condition that is distinct from schizophrenia and has a close relationship with alcohol withdrawal states.

    Method: Systematic review using PRISMA guidelines.

    Results: Of 6205 abstracts found, fifteen studies and ten case reports met criteria and were examined. Read More

    Ghrelin is Related to Personality Differences in Reward Sensitivity and Impulsivity.
    Alcohol Alcohol 2018 Jan;53(1):52-56
    Department of Psychiatry, Yale University School of Medicine, 333 Cedar St., New Haven, CT.
    Aims: Ghrelin, a feeding-related peptide mainly produced in the stomach, has been linked to reward mechanisms for food and drugs of abuse in addition to traits of impulsivity. This study is a secondary analysis of an existing data set designed to examine the direct relationships between fasting ghrelin levels and reward sensitivity/impulsivity in healthy social drinkers.

    Methods: Participants (n = 20) were recruited from an original study examining the subjective effects of alcohol among social drinkers. Read More

    Alcohol Warning Label Awareness and Attention: A Multi-method Study.
    Alcohol Alcohol 2018 Jan;53(1):39-45
    School of Management, Xiamen University, 422 Siming S Rd, Siming Qu, Xiamen Shi, Fujian Sheng, 361005, China.
    Aims: Evaluation of alcohol warning labels requires careful consideration ensuring that research captures more than awareness given that labels may not be prominent enough to attract attention. This study investigates attention of current in market alcohol warning labels and examines whether attention can be enhanced through theoretically informed design. Attention scores obtained through self-report methods are compared to objective measures (eye-tracking). Read More

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