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Aktuelle Urol 2020 Jun 2;51(3):299-308. Epub 2020 Jun 2.

Aktuelle Urol 2020 Jun 2;51(3):248. Epub 2020 Jun 2.

Aktuelle Urol 2020 Jun 2;51(3):244-247. Epub 2020 Jun 2.

Institut für Kryptorchismus Forschung, Kindermedizinisches Zentrum Liestal.

Aktuelle Urol 2020 Jun 2;51(3):241-242. Epub 2020 Jun 2.

Urologische Abteilung Ev. Krankenhaus Witten gGmbH, Lehrstuhl für Geriatrie Universität Witten Herdecke.

Aktuelle Urol 2020 Jun 2;51(3):239-240. Epub 2020 Jun 2.

Urologisches Zentrum Euregio, Aachen I, Praxisklinik am Franziskushospital, Sanatoriumstraße 10, D-52064 Aachen, Deutschland.

Aktuelle Urol 2020 Jun 2;51(3):236-238. Epub 2020 Jun 2.

Organgruppensprecher der Arbeitsgemeinschaft Urologische Onkologie in der Deutschen Krebsgesellschaft e. V., Kuno-Fischer-Str. 8, 14057 Berlin.

Aktuelle Urol 2020 Jun 2;51(3):234-235. Epub 2020 Jun 2.

Aktuelle Urol 2020 Jun 2;51(3):232-234. Epub 2020 Jun 2.

Aktuelle Urol 2020 Jun 2;51(3):231-232. Epub 2020 Jun 2.

Aktuelle Urol 2020 Jun 2;51(3):229-231. Epub 2020 Jun 2.

Aktuelle Urol 2020 Jun 2;51(3):228-229. Epub 2020 Jun 2.

Aktuelle Urol 2020 Jun 2;51(3):251. Epub 2020 Jun 2.

Charité Universitätsmedizin Berlin, Klinik für Urologie.

Aktuelle Urol 2020 Jun 2;51(3):217-218. Epub 2020 Jun 2.

Aktuelle Urol 2020 May 27. Epub 2020 May 27.

Heinrich-Heine-Universität, Medizinische Fakultät, Klinik für Urologie, Düsseldorf.

Even today, radical cystectomy with urinary diversion is one of the most complicated procedures in uro-oncology. Particularly in the long-term course, but also perioperatively, problems caused by urinary diversion play a significant role.Perioperatively, gastrointestinal problems such as an ileus, but also infections and early complications of the different anastomoses are most important. Read More

Aktuelle Urol 2020 May 19. Epub 2020 May 19.

Bakirkoy Dr Sadi Konuk Training and Research Hospital, Urology, Istanbul.

Objective: There are a few studies in the literature investigating the effect of preoperative dutasteride use on bleeding in open simple prostatectomy. We aimed to evaluate the effect of preoperative dutasteride use on perioperative bleeding during open simple prostatectomy.

Methods: We retrospectively analyzed the medical records of all patients who underwent transvesical open prostatectomy due to benign prostatic hyperplasia in our institution between 2008 and 2018. Read More

Aktuelle Urol 2020 Jun 5;51(3):252-257. Epub 2020 May 5.

Universitätsklinikum Ulm, Klinik für Radioonkologie und Strahlentherapie, Ulm.

In the treatment of metastatic prostate cancer, significant improvements have recently been made. In addition to androgen deprivation, various options are available, such as anti-androgen receptor therapies with abiraterone and enzalutamide and taxane-based chemotherapy. It is still being discussed whether oligometastatic patients should only be treated systemically, or whether they benefit from additional local therapy for the primary tumour. Read More

Aktuelle Urol 2020 Jun 23;51(3):271-274. Epub 2020 Apr 23.

Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Klinik für Urologie, Lübeck.

Between 20 and 30 % of patients diagnosed with renal cell carcinoma suffer from metastatic disease by the time of diagnosis and a further 20 - 30 % develop metachronous metastases after initial treatment with curative intent. The therapeutic landscape of metastatic renal cell carcinoma seems be changing rapidly, with new systemic therapies or combination therapies available and established concepts being questioned because of long-awaited data. Apart from systemic therapy, metastases can be treated by surgical resection. Read More

Aktuelle Urol 2020 Apr 14. Epub 2020 Apr 14.

Universitätsklinikum Hamburg-Eppendorf, Klinik und Poliklinik für Urologie, Hamburg.

Radical cystectomy is the gold standard in treatment of muscle invasive bladder carcinoma. Especially for patients with advanced tumours, multimodal therapies play an important role in optimising patient care. In older patients with multiple comorbidities, who are not eligible for surgery, alternative treatment modalities are needed as well. Read More

Aktuelle Urol 2020 Jun 8;51(3):265-270. Epub 2020 Apr 8.

Klinikum rechts der Isar der Technischen Universität München, Klinik für RadioOnkologie und Strahlentherapie, München.

Background:  Local radiation therapy of metastases in prostate cancer patients has become increasingly important in recent years. In order to improve the evaluation of the outcome, we have studied oligometastatic prostate cancer patients who were treated with stereotactic radiation therapy.

Patients And Methods:  24 patients with a total of 30 bone metastases were included in the study. Read More

Aktuelle Urol 2020 Apr 8. Epub 2020 Apr 8.

Universitätsklinikum Münster, Urologie, Münster.

Background:  Abiraterone acetate (AA) is a prodrug of abiraterone, which is an irreversible inhibitor of 17α-hydroxylase/C17, 20-lyase. Since 2011, abiraterone acetate has been available in combination with prednisone/prednisolone (AA + P) for the treatment of metastatic castration-resistant prostate cancer (mCRPC) after pre-treatment with docetaxel, and since 2012 for the treatment of chemotherapy-naïve asymptomatic or mildly symptomatic mCRPC patients. A revision of the guidelines of the European Association of Urology in 2014 redefining castration resistance gave rise to the question of when the treatment of mCRPC with abiraterone acetate plus prednisone should be initiated after prior hormone treatment and how successful it would be. Read More

Aktuelle Urol 2020 Jun 8;51(3):e2. Epub 2020 Apr 8.

Yuksek Ihtisas Training and Research Hospital, Urology, Ankara.

Aktuelle Urol 2020 Apr 7. Epub 2020 Apr 7.

Heinrich-Heine-Universität Düsseldorf, Medizinische Fakultät, Klinik für Urologie.

The increasing knowledge of the influence of the immune system on tumour development and progression has fundamentally changed our understanding of tumour biology in recent years. While the available treatment options for patients with metastatic urothelial carcinoma of the urinary bladder have hardly improved over decades, the advent of immune checkpoint inhibitors has caused major changes in the corresponding treatment landscape.Although cisplatin-based combination therapies remain the main element, additional effective treatment options now exist with the PD-(L)-1 inhibitors atezolizumab, pembrolizumab and nivolumab, which have been approved in Europe. Read More

Aktuelle Urol 2020 Apr 7. Epub 2020 Apr 7.

Abteilung für Urologie, Zentralkrankenhaus Bozen, Italien.

We report the case of an 84-year-old man with the rare diagnosis of a volvulus of an incontinent sigmoid colon urinary conduit after radical cystoprostatectomy due to urinary bladder cancer. To the best of our knowledge, this is the first case in literature of a volvulus of a sigmoid colon conduit. Read More

Aktuelle Urol 2020 Jun 26;51(3):258-264. Epub 2020 Mar 26.

Universitätsklinikum Hamburg-Eppendorf, Martini-Klinik, Hamburg.

Recent advances in functional imaging, such as prostate-specific membrane antigen positron emission tomography (PSMA PET/CT), provide earlier detection of nodal recurrent prostate cancer. Current studies on metastasis-directed therapy in patients with node-only recurrence suggest a positive influence on the prognosis in selected patients. Nevertheless, most studies are retrospective and, due to a lack of high-level evidence, salvage lymph node dissection (SLND) is not recommended by current guidelines. Read More

Aktuelle Urol 2020 Mar 26. Epub 2020 Mar 26.

Klinikum Sankt Georg gGmbH Akademisches Lehrkrankenhaus der Universität Leipzig, Klinik für Urologie und Andrologie, Leipzig.

The following is a case of an 81-year-old male adult who presented to our emergency department with signs of urosepsis. The patient came with an indwelling urinary catheter due to benign prostatic hyperplasia. Extended diagnostic investigation demonstrated an infected urachal cyst as the cause of infection, which was surgically treated. Read More

Aktuelle Urol 2020 04 24;51(2):202-216. Epub 2020 Mar 24.

Aktuelle Urol 2020 Apr 24;51(2):183-185. Epub 2020 Mar 24.

Universitätsmedizin der Johannes-Gutenberg Universität Mainz, Klinik und Poliklinik für Urologie und Kinderurologie, Mainz.

For decades, hormonal therapy was considered an integral part of the treatment regimen for undescended testes, particularly in Europe. However, the available data are controversial. According to many studies and a large meta-analysis, testicular descent can only be achieved in approximately 20 % of cases, whereas a few small studies report better results. Read More

Aktuelle Urol 2020 Apr 24;51(2):121-126. Epub 2020 Mar 24.

Cantonal Hospital Lucerne Children's Hospital, Pediatric Surgery, Luzern.

Hydronephrosis in infants and children is most commonly due to a congenital, intrinsic obstruction of the uretero-pelvic junction. The Gold standard of care is defined as a dismembered pyeloplasty, nowadays mostly performed in a minimally-invasive procedure, either through a laparoscopic (also robotic-assisted) or retroperitoneoscopic approach. Less common is an extrinsic obstruction of the ureter or the uretero-pelvic junction caused by an aberrant crossing pole vessel, a condition more likely to affect children beyond infancy. Read More

Aktuelle Urol 2020 Apr 24;51(2):109-110. Epub 2020 Mar 24.

Aktuelle Urol 2020 Apr 24;51(2):106-108. Epub 2020 Mar 24.

Aktuelle Urol 2020 Apr 24;51(2):104. Epub 2020 Mar 24.

Urologische Klinik, Evangelisches Krankenhaus Witten gGmbH.

Aktuelle Urol 2020 04 24;51(2):101-102. Epub 2020 Mar 24.

Organgruppensprecher der Arbeitsgemeinschaft Urologische Onkologie in der Deutschen Krebsgesellschaft e. V., Kuno-Fischer-Str. 8, 14057 Berlin.

Aktuelle Urol 2020 04 24;51(2):98-100. Epub 2020 Mar 24.

Aktuelle Urol 2020 04 24;51(2):97-98. Epub 2020 Mar 24.

Aktuelle Urol 2020 04 24;51(2):94-96. Epub 2020 Mar 24.

Aktuelle Urol 2020 04 24;51(2):92-94. Epub 2020 Mar 24.

Aktuelle Urol 2020 04 24;51(2):90-92. Epub 2020 Mar 24.

Aktuelle Urol 2020 Apr 24;51(2):114-115. Epub 2020 Mar 24.

Universitätsmedizin Mannheim, Zentrum für Kinder-, Jugend- und rekonstruktive Urologie, Mannheim.

Aktuelle Urol 2020 Apr 24;51(2):81. Epub 2020 Mar 24.

Klin Padiatr 2020 May 19;232(3):136-142. Epub 2020 Mar 19.

Department of Pediatric Oncology, Hematology and Hemostaseology, University of Leipzig Faculty of Medicine, Leipzig.

Background: Recent research shows that parents of children suffer from fear of progression (FoP), the fear of further disease progression. It is most possible that children also develop FoP, which could impair treatment and psychological health. The aim of this study is to adapt the adult's version of the Fear of Progression Questionnaire - Short Form (FoP-Q-SF) for children and to examine the psychometric properties in pediatric cancer patients. Read More

Aktuelle Urol 2020 Mar 18. Epub 2020 Mar 18.

Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Urologie, Lübeck.

When LH-RH (now: GNRH) analogues were first used for the treatment of prostate cancer, the castration level was arbitrarily defined as a testosterone level of less than 50 ng/dl. Since then, numerous studies have shown that a permanent lowering of the testosterone level, e. g. Read More

Aktuelle Urol 2020 Jun 5;51(3):285-289. Epub 2020 Mar 5.

Yuksek Ihtisas Training and Research Hospital, Urology, Ankara.

Objective:  We aimed to investigate the possible association between testicular cancer prognosis and De Ritis ratio (AST/ALT).

Methods:  The medical records of all patients who underwent radical inguinal orchiectomy at a single tertiary in Istanbul, Turkey between 2006 and 2017 were retrospectively analyzed. Investigated parameters included patients' demographics, complete blood count and blood biochemistry results, pathology results, treatment schemes, imaging results, and survival. Read More

Aktuelle Urol 2020 Mar 5. Epub 2020 Mar 5.

Chongqing Medical University First Affiliated Hospital, Urology Department, Chongqing, China.

A 19-year-old man complaining of anuria for 1 day was presented. A ureteral stent was indwelled 3 months ago for preventing ureteral obstruction and protecting kidney function. Abdominopelvic computed tomography (CT) scan revealed a solitary pelvic ectopic kidney (PEK) and severe hydronephrosis. Read More

Aktuelle Urol 2020 Mar 3. Epub 2020 Mar 3.

Klinikum Sankt Georg gGmbH Akademisches Lehrkrankenhaus der Universität Leipzig, Urologie, Leipzig.

The following is a case report of a 54-year-old female who presented with persistent macrohaematuria with bladder tamponade three weeks after percutaneous nephrolithotomy. Angiography revealed an intrarenal aneurysm, which was closed by coiling, resulting in complete cessation of bleeding. Read More

J Neurointerv Surg 2020 Feb 27. Epub 2020 Feb 27.

Department of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Objective: To analyze outcome and its predictors after endovascular treatment (ET) in stroke patients suffering from large vessel occlusion with large pre-treatment infarct cores defined by an Alberta Stroke Program Early CT Score (ASPECTS) <6.

Methods: We analyzed data from an industry-independent, multicenter, prospective registry (German Stroke Registry - Endovascular Treatment) which enrolled consecutive patients treated by ET (June 2015-April 2018) with different devices. Multivariate logistic regression analyses identified predictors of independent outcome (IO) defined as a modified Rankin Scale (mRS) 0-2, and mortality at 90 days in patients with ASPECTS <6. Read More

Aktuelle Urol 2020 Feb 14. Epub 2020 Feb 14.

Universitätsmedizin Mannheim, Zentrum für Kinder-, Jugend- und rekonstruktive Urologie, Mannheim.

Aktuelle Urol 2020 Apr 13;51(2):191-194. Epub 2020 Feb 13.

Universitätsklinikum Hamburg-Eppendorf, Klinik und Poliklinik für Urologie, Hamburg.

Cryptorchism is one of the most frequent diagnoses in early childhood with an incidence of up to 3 - 8 %. The goal of any treatment is scrotal positioning of the testis until the end of the first year of life to prevent degenerative changes of the testis. This often requires a surgical procedure. Read More

Aktuelle Urol 2020 Feb 4;51(1):71-80. Epub 2020 Feb 4.

Aktuelle Urol 2020 Feb 4;51(1):65-70. Epub 2020 Feb 4.

Neuro-Urologie im Chirurgischen Zentrum, Universitätsklinikum Bonn.

In 2009, the first complete guideline for the diagnostic evaluation and treatment of urinary incontinence in geriatric patients, commissioned by the German Society of Geriatrics, was developed by the working group Urinary Incontinence and published in the guideline registry of the AWMF (Association of the Scientific Medical Societies in Germany). We are presenting an up-to-date summary of the most recent update published as an "S2e" guideline in January 2019. This is the only valid, up-to-date and complete guideline on urinary incontinence in German language. Read More

Aktuelle Urol 2020 Feb 4;51(1):59-64. Epub 2020 Feb 4.

Universitat Witten, Lehrstuhl für Geriatrie, Witten.

Background:  Transurethral resection of the prostate (TUR-P) is considered the gold standard in the surgical treatment of symptomatic benign prostatic hyperplasia. Besides the conventional TUR-P, there are numerous technological modifications of the procedure. An increasing use of the 180 W Greenlight-XPS™ laser vaporisation of the prostate (GLL) has been observed recently. Read More