304,734 results match your criteria Agricultural Economics-zemedelska Ekonomika[Journal]


Indocyanine Green-Coated Polycaprolactone Micelles for Fluorescence Imaging of Tumors.

ACS Appl Bio Mater 2020 Apr 8;3(4):2344-2349. Epub 2020 Mar 8.

Department of Bioengineering, School of Engineering and Applied Sciences, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.

Recently, near-infrared (NIR) fluorescent dyes such as indocyanine green (ICG) have received tremendous interest as contrast agents for use in fluorescence-guided, intraoperative cancer resection surgery. However, despite showing great promise, ICG has many shortcomings such as rapid clearance and poor tumor accumulation. To improve the selective accumulation of ICG within tumors, numerous groups have formulated ICG into nanoparticles, but these approaches can suffer from rapid leakage of ICG, use of materials that exhibit poor or incomplete excretion, or complex chemistries that are not easily amenable to scale up for clinical use. Read More

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http://dx.doi.org/10.1021/acsabm.0c00091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245056PMC

Preparation of Highly Porous Graphitic Activated Carbon as Electrode Materials for Supercapacitors by Hydrothermal Pretreatment-Assisted Chemical Activation.

ACS Omega 2020 May 6;5(19):11058-11067. Epub 2020 May 6.

Key Laboratory of Straw Biology and Utilization, The Ministry of Education, Jilin Agricultural University, Changchun 130118, China.

The obstruction of traditional chemical activation lies in the addition of excessive catalysts to prepare the highly porous graphitic activated carbon (HPGAC), we propose the hydrothermal pretreatment-assisted chemical activation method to synthesize HPGAC as electrode materials using a small amount of Na-based catalysts (20 wt %). Hydrolysis accompanied by the strong depolymerization and reorganization of the coal framework is beneficial to the removal of different kinds of oxygen-containing structures (including cross-linking bonds, functional groups, and heterocycles) from lignite; thus, the deoxidization effect of hydrothermal carbonization (HTC) on hydrochar gradually strengthens with the increase in pretreatment temperature from 180 to 300 °C, resulting in the formation of a lot of disordered nanostructures and a smooth and compact surface. In the subsequent chemical activation stage, the microstructure of hydrochar is beneficial to the formation of a lot of graphene-like sheets and developed micropores even under a small amount of Na-based catalysts (20 wt %). Read More

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http://dx.doi.org/10.1021/acsomega.0c00938DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241011PMC

Effects of light intensities and varying watering intervals on growth, tissue nutrient content and antifungal activity of hydroponic cultivated L. under greenhouse conditions.

Heliyon 2020 May 17;6(5):e03906. Epub 2020 May 17.

Department of Horticulture Sciences, Faculty of Applied Sciences, Cape Peninsula University of Technology, Symphony Way, Bellville, 7535, Cape Town, South Africa.

Optimization of the quality and quantity of medicinal materials during cultivation could improve the value of medicinal plants. Light intensity and water availability affect physiological processes and growth of plants. L. Read More

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http://dx.doi.org/10.1016/j.heliyon.2020.e03906DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235940PMC

Antioxidant Potential Overviews of Secondary Metabolites (Polyphenols) in Fruits.

Int J Food Sci 2020 7;2020:9081686. Epub 2020 May 7.

College of Food Science and Engineering, Jilin Agricultural University, Changchun 130118, China.

The rise in consumption of energy-dense foods has resulted in the displacement of several essential dietary gaps, causing numerous long-lasting diseases, including obesity, stroke, hypertension, and several forms of cancer. Epidemiological studies encourage more fruit consumption to prevent these diseases. The defensive mechanisms provided by these fruits against illness are due to the existence of several antioxidants. Read More

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http://dx.doi.org/10.1155/2020/9081686DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229537PMC

Machine Learning-Based Predictive Farmland Optimization and Crop Monitoring System.

Scientifica (Cairo) 2020 10;2020:9428281. Epub 2020 May 10.

Department of Computer Science, Landmark University, Omu-Aran, Kwara State, Nigeria.

E-agriculture is the integration of technology and digital mechanisms into agricultural processes for more efficient output. This study provided a machine learning-aided mobile system for farmland optimization, using various inputs such as location, crop type, soil type, soil pH, and spacing. Random forest algorithm and BigML were employed to analyze and classify datasets containing crop features that generated subclasses based on random crop feature parameters. Read More

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http://dx.doi.org/10.1155/2020/9428281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238365PMC

Whole-genome sequence of (mulberry Sanghuang) reveals its unique medicinal values.

J Adv Res 2020 Jul 28;24:325-335. Epub 2020 Apr 28.

Sericultural Research Institute, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, People's Republic of China.

(Schwein.) Pat, a species of 'Sanghuang', has been well-documented for various medicinal uses, but the genome information and active constituents are largely unknown. Here, we sequenced the whole-genome of , identified phenylpropanoids as its key anti-cancer components, and deduced their biosynthesis pathways. Read More

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http://dx.doi.org/10.1016/j.jare.2020.04.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235939PMC

Intelligent Diagnosis of Heart Murmurs in Children with Congenital Heart Disease.

J Healthc Eng 2020 9;2020:9640821. Epub 2020 May 9.

Department of Mechanical Engineering, Texas Tech University, Lubbock, TX 79409, USA.

Heart auscultation is a convenient tool for early diagnosis of heart diseases and is being developed to be an intelligent tool used in online medicine. Currently, there are few studies on intelligent diagnosis of pediatric murmurs due to congenital heart disease (CHD). The purpose of the study was to develop a method of intelligent diagnosis of pediatric CHD murmurs. Read More

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http://dx.doi.org/10.1155/2020/9640821DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238385PMC

Regulation of Iron Homeostasis and Related Diseases.

Mediators Inflamm 2020 2;2020:6062094. Epub 2020 May 2.

Key Laboratory of Agro-Ecological Processes in Subtropical Region, Hunan Research Center of Livestock & Poultry Sciences, South-Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha, Hunan 410125, China.

The liver is the organ for iron storage and regulation; it senses circulating iron concentrations in the body through the BMP-SMAD pathway and regulates the iron intake from food and erythrocyte recovery into the bloodstream by secreting hepcidin. Under iron deficiency, hypoxia, and hemorrhage, the liver reduces the expression of hepcidin to ensure the erythropoiesis but increases the excretion of hepcidin during infection and inflammation to reduce the usage of iron by pathogens. Excessive iron causes system iron overload; it accumulates in never system and damages neurocyte leading to neurodegenerative diseases such as Parkinson's syndrome. Read More

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http://dx.doi.org/10.1155/2020/6062094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212278PMC

Synergistic, aqueous PAH degradation by ultrasonically-activated persulfate depends on bulk temperature and physicochemical parameters.

Ultrason Sonochem 2020 May 17;67:105172. Epub 2020 May 17.

Department of Civil, Environmental, and Geodetic Engineering, The Ohio State University, Columbus, OH 43210, United States. Electronic address:

Coupling ultrasound with other remediation technologies has potential to result in synergistic degradation of contaminants. In this work, we evaluated synergisms from adding high-power ultrasound (20 kHz; 250 W) to activated persulfate over a range of bulk temperatures (20-60 °C). We studied the aqueous degradation kinetics of three polycyclic aromatic hydrocarbons (PAHs: naphthalene, phenanthrene, and fluoranthene) treated by ultrasound-alone, heat-activated persulfate, and combined ultrasonically-activated persulfate (US-PS). Read More

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http://dx.doi.org/10.1016/j.ultsonch.2020.105172DOI Listing

Quantitative and qualitative characterization of dual scale mechanical enhancement on cellulosic and crystalline-structural variation of NaOH treated wheat straw.

Bioresour Technol 2020 May 18;312:123535. Epub 2020 May 18.

College of Engineering, China Agricultural University, Box 191, Beijing 100083, China. Electronic address:

In order to explore the effects of different mechanical fragmentation on cellulose separation and cellulose polymorphic transformation of wheat straw during alkali treatment, one coarse milled (CM) and two ball milled wheat straw samples (BM30 and BM120) were treated with different NaOH concentrations (1%-10%), and the lignocellulosic compositions and crystalline-structural various were quantitative and qualitative characterized. The quantitative equations between cellulose content and NaOH concentration of different mechanical treated samples were Y = 69.8-35. Read More

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http://dx.doi.org/10.1016/j.biortech.2020.123535DOI Listing

Enhancement and improvement of selenium in soil to the resistance of rape stem against Sclerotinia sclerotiorum and the inhibition of dissolved organic matter derived from rape straw on mycelium.

Environ Pollut 2020 May 19;265(Pt A):114827. Epub 2020 May 19.

College of Resources and Environment, Huazhong Agricultural University, Hubei Provincial Engineering Laboratory for New-Type Fertilizer, Research Center of Trace Elements, Hubei Key Laboratory of Soil Environment and Pollution Remediation, Wuhan, 430070, China; Key Laboratory of Arable Land Conservation (Middle and Lower Reaches of Yangtze River), Ministry of Agriculture and Rural Affairs, Wuhan, 430070, China. Electronic address:

Sclerotinia stem rot (SSR), caused by Sclerotinia sclerotiorum (S. sclerotiorum), one of the most destructive diseases in many crops including Brassica napus L. The extensive use of fungicides to control S. Read More

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http://dx.doi.org/10.1016/j.envpol.2020.114827DOI Listing

Population-level variation in neonicotinoid tolerance in nymphs of the Heptageniidae.

Environ Pollut 2020 May 14;265(Pt B):114803. Epub 2020 May 14.

Department of Forestry and Natural Resources, Purdue University, West Lafayette, IN, 47907, USA.

Anthropogenic activities can have significant ecological and evolutionary consequences on populations and communities. In the United States, neonicotinoid insecticides are widespread across the agricultural Midwest and frequently detected in stream systems. Their effect on Heptageniidae mayflies is a major concern because they are highly sensitive to neonicotinoids and have some of the lowest reported tolerance values of any organism. Read More

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http://dx.doi.org/10.1016/j.envpol.2020.114803DOI Listing

Novel insights into effects of silicon-rich biochar (Sichar) amendment on cadmium uptake, translocation and accumulation in rice plants.

Environ Pollut 2020 May 10;265(Pt B):114772. Epub 2020 May 10.

Department of Environmental Science, Zhejiang University, Hangzhou, Zhejiang, 310058, China. Electronic address:

The effects and mechanisms of biochars with different silicon (Si) contents on Cadmium (Cd) uptake, translocation and accumulation in rice plants are not fully understood. Herein, we report a pot study to disentangle the interaction mechanisms of Si-rich biochars (Sichar RH300, RH700) and Si-deficient biochars (WB300, WB700) with high-Si soil (HSS) and low-Si soil (LSS) on Cadmium (Cd) and Si accumulation in rice (including grains, straw, and roots). Sichar was found to be better than Si-deficient biochars in reducing Cd uptake and accumulation in rice, and RH300 amendment was better than the RH700 treatment. Read More

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http://dx.doi.org/10.1016/j.envpol.2020.114772DOI Listing

3-Acetyldeoxynivalenol induces lysosomal membrane permeabilization-mediated apoptosis and inhibits autophagic flux in macrophages.

Environ Pollut 2020 May 7;265(Pt B):114697. Epub 2020 May 7.

State Key Laboratory of Animal Nutrition, China Agricultural University, Beijing, 100193, China. Electronic address:

3-Acetyldeoxynivalenol (3-Ac-DON), the acetylated derivative of deoxynivalenol (DON), has been reported to be coexisted with DON in various cereal grains. Ingestion of grain-based food products contaminated by 3-Ac-DON might exert deleterious effects on the health of both humans and animals. However, the biological toxicity of 3-Ac-DON on macrophages and the underlying mechanisms remain largely unknown. Read More

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http://dx.doi.org/10.1016/j.envpol.2020.114697DOI Listing

Earthworm as an alternative protein source in poultry and fish farming: Current applications and future perspectives.

Sci Total Environ 2020 May 15;734:139460. Epub 2020 May 15.

Department of Agricultural and Environmental Science, Università degli Studi di Milano, via Celoria 2, 20133 Milan, Italy. Electronic address:

Among the different agricultural activities, the livestock is one of the most impacting on the environment. The feeding of animals is often the main responsible of the adverse environmental impact related to animal productions. Above all for intensive production, the consumption of protein feed is a key aspect for the achievement of sustainable production processes. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2020.139460DOI Listing

Copper accumulation in agricultural soils: Risks for the food chain and soil microbial populations.

Sci Total Environ 2020 May 15;734:139434. Epub 2020 May 15.

Department of Agricultural Sciences, Division of Microbiology, University of Naples Federico II, Via Università 100, Portici 80055, Naples, Italy; Task Force on Microbiome Studies, University of Naples Federico II, Naples, Italy. Electronic address:

The long-term use of Cu-based fungicides at doses of several kilograms per hectare stimulated a wide debate about the human health and environmental risks of the progressive accumulation of Cu in agricultural soils. Here, the health risks due to copper accumulation in agricultural soils were evaluated with a survey in intensive agricultural land of the Campania region (Italy), aiming to evaluate Cu accumulation in food crops. The health risk due to dietary exposure was estimated by using the Hazard Quotient (HQ), calculated as the ratio between the average daily dose and the reference dose of copper, suggesting that when HQ > 1 there is a potential risk for consumers. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2020.139434DOI Listing

Exposure pathways, levels and toxicity of polybrominated diphenyl ethers in humans: A review.

Environ Res 2020 Apr 30;187:109531. Epub 2020 Apr 30.

School of Public Health, Xinxiang Medical University, Xinxiang, 453003, China. Electronic address:

Polybrominated diphenyl ethers (PBDEs) are extensively used as brominated flame retardants (BFRs) in different types of materials, which have been listed as Persistent Organic Pollutants (POPs) by the Stockholm Convention in 2009 and 2017. Due to their ubiquities in the environment and toxicities, PBDEs have posed great threat to both human health and ecosystems. The aim of this review is to offer a comprehensive understanding of the exposure pathways, levels and trends and associated health risks of PBDEs in human body in a global scale. Read More

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http://dx.doi.org/10.1016/j.envres.2020.109531DOI Listing

Effects of low flow and co-occurring stressors on structural and functional characteristics of the benthic biofilm in small streams.

Sci Total Environ 2020 May 11;733:139331. Epub 2020 May 11.

Department of Biology, Aarhus University, Denmark.

Low flow and co-occurring stress is a more and more frequent phenomenon these years in small agricultural streams as a consequence of climate change. In the present study we explored short and longer term structural responses of the stream benthic algae community and biofilm metabolism to multiple stress in small streams applying a semi-experimental approach. We hypothesized that i) a reduction in flow in combination with secondary stress (nutrients and sediments) have immediate effects on the benthic algae community in terms of biomass (chlorophyll a, biovolume), taxonomic and trait (lifeform and size distribution) compositions as well as on metabolism (GPP and CR), and ii) that changes in the benthic algae community persist due to altered environmental settings but that functional redundancy among benthic algae species provides a high level of resilience in metabolism (GPP and CR). Read More

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http://dx.doi.org/10.1016/j.scitotenv.2020.139331DOI Listing

Low-molecular-weight glutenin subunit LMW-N13 improves dough quality of transgenic wheat.

Food Chem 2020 May 12;327:127048. Epub 2020 May 12.

College of Plant Protection, Shandong Agricultural University, No. 61, Daizong Street, Taian, Shandong Province, China. Electronic address:

In our previous study, a novel LMW-GS designated as LMW-N13 with a unique molecular structure was identified from Aegilops uniaristata. LMW-N13 has been characterized as the largest LMW-GS, so far, and possesses an extra cysteine residue compared with typical LMW-GS. In order to analyze the contribution of LMW-N13 to dough quality, in this work, three transgenic wheat lines overexpressing LMW-N13 were generated. Read More

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http://dx.doi.org/10.1016/j.foodchem.2020.127048DOI Listing

Homogeneous fluorescent immunoassay for the simultaneous detection of chloramphenicol and amantadine via the duplex FRET between carbon dots and WS nanosheets.

Food Chem 2020 May 20;327:127107. Epub 2020 May 20.

Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Laboratory of Food Quality and Safety, China Agricultural University, Beijing 100193, China. Electronic address:

Herein, we proposed a duplex and homogeneous fluorescent immunoassay for the simultaneous detection of amantadine (AMD) and chloramphenicol (CAP) residue in chicken breast with both high sensitivity and short assay time. The immunoassay was based on the fluorescence resonance energy transfer (FRET) between hapten-labeled carbon dots (CDs) and antibody-modified WS nanosheets. To achieve the duplex FRET, polyethyleneimine-functionalized blue and green emissive CDs with separated emission were synthesized via a one-pot hydrothermal method and directly coupled with the haptens of AMD and CAP, serving as the energy donors. Read More

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http://dx.doi.org/10.1016/j.foodchem.2020.127107DOI Listing

Soy glycinin-soyasaponin mixtures at oil-water interface: Interfacial behavior and O/W emulsion stability.

Food Chem 2020 May 18;327:127062. Epub 2020 May 18.

College of Food Science and Technology, Bohai University, Food Safety Key Lab of Liaoning Province, National & Local Joint Engineering Research Center of Storage, Processing and Safety Control Technology for Fresh Agricultural and Aquatic Products, Jinzhou, Liaoning 121013, China. Electronic address:

Soy glycinin (11S) was mixed with soyasaponin (Ssa) to elucidate the mechanism(s) involved in the stabilization of emulsions by mixed systems based on dynamic interfacial tension and dilatational rheology at the oil-water interface. The short/long-term properties of oil-in-water emulsions stabilized by 11S-Ssa mixtures included droplet-size distribution, droplet ζ-potential, microstructure, and Turbiscan stability index. The combination of Ssa (0. Read More

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http://dx.doi.org/10.1016/j.foodchem.2020.127062DOI Listing

Detection of toxic methylenecyclopropylglycine and hypoglycin A in litchi aril of three Chinese cultivars.

Food Chem 2020 May 11;327:127013. Epub 2020 May 11.

Key Laboratory of Plant Resources Conservation and Sustainable Utilization, Key Laboratory of Post-harvest Handling of Fruits of Ministry of Agriculture and Rural Affairs, Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China; Center of Economic Botany, Core Botanical Gardens, Chinese Academy of Sciences, Guangzhou 510650, China. Electronic address:

As a subtropical fruit with high commercial values, litchi is also a source of methylenecyclcopropylglycine (MCPG) and hypoglycin A (HGA), which could cause hypoglycemia and fatal encephalopathy in human. In this work, a quantitative method was developed well to detect MCPG and HGA present in litchi aril of different cultivars. Method validation was evaluated well by linearity, recovery, precision and sensitivity. Read More

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http://dx.doi.org/10.1016/j.foodchem.2020.127013DOI Listing

Minimizing lipid oxidation during pH-shift processing of fish by-products by cross-processing with lingonberry press cake, shrimp shells or brown seaweed.

Food Chem 2020 May 16;327:127078. Epub 2020 May 16.

Department of Biology and Biological Engineering-Food and Nutrition Science, Chalmers University of Technology, SE 412 96 Gothenburg, Sweden. Electronic address:

The potential of cross-processing herring or salmon by-products with brown seaweed, shrimp peeling by-products and lingonberry press cake (called "helpers") to minimize lipid oxidation during acid/alkaline pH-shift protein isolation was evaluated. Lingonberry press cake remarkably reduced levels of lipid hydroperoxides, malondialdehyde (MDA) and 4-hydroxy-trans2-hexenal (HHE) in both herring and salmon protein isolates (PI) while seaweed and shrimp by-product mitigated generation of MDA and HHE in herring PI. The salmon PI, however, by itself had very low oxidation levels. Read More

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http://dx.doi.org/10.1016/j.foodchem.2020.127078DOI Listing

Effect of salt promote the muscle triglyceride hydrolysis during dry-salting by inducing the phosphorylation of adipose tissue triglyceride lipase (ATGL) and hormone-sensitive lipase (HSL) and lipid droplets splitting.

Food Chem 2020 May 18;327:127061. Epub 2020 May 18.

College of Food Science and Technology & MOE Key Laboratory of Environment Correlative Dietology, Huazhong Agricultural University, Wuhan 430070, China; Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology and Business University (BTBU), Beijing 100048, China. Electronic address:

This study mainly investigated the effect of different salt concentrations (1, 3, or 5%) on triglycerides (TG) hydrolysis in muscle during salting by analyzing moisture distribution, TG hydrolysis, TG hydrolase activity, native and phosphorylated adipose triglyceride lipase (ATGL) and hormone-sensitive lipase (HSL) protein content, lipid droplets morphology, and muscle microstructure. The results showed that increasing salt concentration could significantly decrease T moisture proportion and relaxation time (p < 0.05), which was more beneficial to the lipase activity. Read More

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http://dx.doi.org/10.1016/j.foodchem.2020.127061DOI Listing

The analysis of the effects of high hydrostatic pressure (HHP) on amylose molecular conformation at atomic level based on molecular dynamics simulation.

Food Chem 2020 May 19;327:127047. Epub 2020 May 19.

Shaanxi University of Science and Technology, School of Food and Biological Engineering, Xi'an, Shaanxi Province 710021, China. Electronic address:

For more effective using of HHP (high hydrostatic pressure) in starch processing, in this study, molecular dynamics simulation was used to explore the effects of pressure on amylose molecular conformation at the atomic level. The results shown that, firstly, high pressure decreased the intramolecular hydrogen bonds and increased the amylose-solvent hydrogen bonds, which is consistent with the process of high pressure starch gelatinization. Secondly, high pressure made amylose polymers more "stout". Read More

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http://dx.doi.org/10.1016/j.foodchem.2020.127047DOI Listing

Effects of triphenyl phosphate on ciliate protozoa Tetrahymena thermophila following acute exposure and sub-chronic exposure.

Ecotoxicol Environ Saf 2020 May 23;200:110757. Epub 2020 May 23.

College of Fisheries, Huazhong Agricultural University, Wuhan, 430070, China. Electronic address:

Triphenyl phosphate (TPHP) is one of the most widely used organophosphate flame retardants (OPFRs) and is frequently detected in a variety of environmental media. Previous studies reported that TPHP had toxic effects on vertebrates, but little toxic information was available in lower trophic aquatic organisms which were more sensitive to the exposure of many toxic substances. In this study, protozoa Tetrahymena thermophila (T. Read More

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http://dx.doi.org/10.1016/j.ecoenv.2020.110757DOI Listing

Elucidation of the complete biosynthetic pathway of the main triterpene glycosylation products of Panax notoginseng using a synthetic biology platform.

Metab Eng 2020 May 23. Epub 2020 May 23.

Key Laboratory of Systems Microbial Biotechnology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, China. Electronic address:

UDP-glycosyltransferase (UGT)-mediated glycosylation is a widespread modification of plant natural products (PNPs), which exhibit a wide range of bioactivities, and are of great pharmaceutical, ecological and agricultural significance. However, functional annotation is available for less than 2% of the family 1 UGTs, which currently has 20,000 members that are known to glycosylate several classes of PNPs. This low percentage illustrates the difficulty of experimental study and accurate prediction of their function. Read More

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http://dx.doi.org/10.1016/j.ymben.2020.05.007DOI Listing

Anti-melanogenic effects of epigallocatechin-3-gallate (EGCG), epicatechin-3-gallate (ECG) and gallocatechin-3-gallate (GCG) via down-regulation of cAMP/CREB /MITF signaling pathway in B16F10 melanoma cells.

Fitoterapia 2020 May 23:104634. Epub 2020 May 23.

Key Laboratory of Tea Science of Ministry of Education, Hunan Agricultural University, Changsha, China; National Research Center of Engineering Technology for Utilization of Functional Ingredients from Botanicals, Hunan Agricultural University, Changsha, China; Collaborative Innovation Centre of Utilization of Functional Ingredients from Botanicals, Hunan Agricultural University, Changsha, China. Electronic address:

Tea catechins, the main bioactive polyphenols in green tea, are well known for their health promoting effects. Previous studies have shown that gallocatechin-3-gallate (GCG), epigallocatechin-3-gallate (EGCG) and epicatechin-3-gallate (ECG) exerted strong inhibitory effects on mushroom tyrosinase activity in vitro, whilst EGCG inhibited melanogenesis in vivo, yet the underlying mechanisms are not entirely clear. In this study, we (i) evaluated and compared the inhibitory effects of the main tea catechins (GCG, EGCG, and ECG) on melanogenesis in B16F10 melanoma cells, and (ii) explain the underlying mechanisms. Read More

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http://dx.doi.org/10.1016/j.fitote.2020.104634DOI Listing

iTRAQ-based comparative proteomic analysis reveals high temperature accelerated leaf senescence of tobacco (Nicotiana tabacum L.) during flue-curing.

Genomics 2020 May 23. Epub 2020 May 23.

Department of Agronomy, College of Agriculture and Biotechnology, Key Laboratory of Crop Germplasm Resource, Zhejiang University, Hangzhou 310058, PR China. Electronic address:

Tobacco (Nicotiana tabacum) is extensively cultivated all over the world for its economic value. During curing and storage, senescence occurs, which is associated with physiological and biochemical changes in postharvest plant organs. However, the molecular mechanisms involved in accelerated senescence due to high temperatures in tobacco leaves during curing need further elaboration. Read More

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http://dx.doi.org/10.1016/j.ygeno.2020.05.019DOI Listing

Hepatoprotective effects of hydroxysafflor yellow A in D-galactose-treated aging mice.

Eur J Pharmacol 2020 May 23:173214. Epub 2020 May 23.

College of Life Science, Engineering Research Center of the Chinese Ministry of Education for Bioreactor and Pharmaceutical Development, Jilin Agricultural University, Changchun, 130118, China. Electronic address:

Hydroxysafflor yellow A (HSYA) is an effective chemical component isolated from Chinese herb Carthamus tinctorius L. In present study, we aimed to evaluate the effects of HSYA on D-galactose- (D-gal-) induced aging in mice, and to elucidate the underlying mechanism. Male C57BL/6 mice were intraperitoneal injection of D-gal and HSYA for 8 weeks. Read More

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http://dx.doi.org/10.1016/j.ejphar.2020.173214DOI Listing

Comparative analysis of RNA-binding proteomes under Arabidopsis thaliana-Pst DC3000-PAMP interaction by orthogonal organic phase separation.

Int J Biol Macromol 2020 May 23. Epub 2020 May 23.

Dalian Engineering Research Center for Carbohydrate Agricultural Preparations, Liaoning Provincial Key Laboratory of Carbohydrates, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address:

RNA-binding proteins (RBPs) are pivotal participants in post-transcriptional gene regulation. They interact with RNA directly to perform several post-transcriptional RNA regulatory functions or direct metabolic processes. Despite the essential importance, the understanding of plant RBPs is elementary, which derives mainly from other kingdoms via bioinformatic extrapolation or mRNA-binding proteins captured through UV crosslinked method. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2020.05.164DOI Listing

Effects of Ochratoxin A exposure on DNA damage in porcine granulosa cells in vitro.

Toxicol Lett 2020 May 23. Epub 2020 May 23.

College of Life Sciences, Key Laboratory of Animal Reproduction and Germplasm Enhancement in Universities of Shandong, Qingdao Agricultural University, Qingdao 266109, China. Electronic address:

Ochratoxin A (OTA), a feed mycotoxin, tends to impair the reproductive performance of animals. Our previous studies have demonstrated that OTA exposure inhibits porcine ovarian granulosa cell (GC) proliferation and induces their apoptosis, but the underlying toxic mechanism is still uncertain. In this study, we explored the OTA exposure on porcine GCs in vitro and found that OTA exposure inhibited the proliferation of porcine GCs and arrested cell cycle of GCs in the G2/M phase. Read More

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http://dx.doi.org/10.1016/j.toxlet.2020.05.011DOI Listing

'What I cannot create, I do not understand': functionally validated synergism of metabolic and target site insecticide resistance.

Proc Biol Sci 2020 May 27;287(1927):20200838. Epub 2020 May 27.

Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology Hellas, 100 N. Plastira Street, 70013 Heraklion, Crete, Greece.

The putative synergistic action of target-site mutations and enhanced detoxification in pyrethroid resistance in insects has been hypothesized as a major evolutionary mechanism responsible for dramatic consequences in malaria incidence and crop production. Combining genetic transformation and CRISPR/Cas9 genome modification, we generated transgenic lines expressing pyrethroid metabolizing P450 enzymes in a genetic background along with engineered mutations in the voltage-gated sodium channel () known to confer target-site resistance. Genotypes expressing the yellow fever mosquito while also bearing the mutation displayed substantially greater resistance ratio (RR) against deltamethrin than the product of each individual mechanism (RR: 19. Read More

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http://dx.doi.org/10.1098/rspb.2020.0838DOI Listing

Diet quantity influences caste determination in honeybees ().

Proc Biol Sci 2020 May 27;287(1927):20200614. Epub 2020 May 27.

Department of Biological Sciences, North Dakota State University, PO Box 6050, Fargo, ND 58108, USA.

In species that care for their young, provisioning has profound effects on offspring fitness. Provisioning is important in honeybees because nutritional cues determine whether a female becomes a reproductive queen or sterile worker. A qualitative difference between the larval diets of queens and workers is thought to drive this divergence; however, no single compound seems to be responsible. Read More

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http://dx.doi.org/10.1098/rspb.2020.0614DOI Listing

Indonesian children fecal microbiome from birth until weaning was different from microbiomes of their mothers.

Gut Microbes 2020 May 26:1-19. Epub 2020 May 26.

Department of Microbiology & Immunology, Yong Loo Lin School of Medicine, National University of Singapore , Singapore.

Gastrointestinal (GI) microbiota play an important role in human health and wellbeing and the first wave of gut microbes arrives mostly through vertical transmission from mother to child. This study has undertaken to understand the microbiota profile of healthy Southeast Asian mother-infant pairs. Here, we examined the fecal, vaginal and breast milk microbiota of Indonesian mothers and the fecal microbiota of their children from less than 1 month to 48 months old. Read More

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http://dx.doi.org/10.1080/19490976.2020.1761240DOI Listing

Viral Hacks of the Plant Vasculature: The Role of Phloem Alterations in Systemic Virus Infection.

Annu Rev Virol 2020 May 26. Epub 2020 May 26.

Institute of Bioscience and Biotechnology Research, University of Maryland, College Park, Maryland 20742, USA; email:

For plant viruses, the ability to load into the vascular phloem and spread systemically within a host is an essential step in establishing a successful infection. However, access to the vascular phloem is highly regulated, representing a significant obstacle to virus loading, movement, and subsequent unloading into distal uninfected tissues. Recent studies indicate that during virus infection, phloem tissues are a source of significant transcriptional and translational alterations, with the number of virus-induced differentially expressed genes being four- to sixfold greater in phloem tissues than in surrounding nonphloem tissues. Read More

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http://dx.doi.org/10.1146/annurev-virology-010320-072410DOI Listing

Comparative Metabolism of Gelsenicine in Liver Microsomes from Humans, Pigs, Goats and Rats.

Rapid Commun Mass Spectrom 2020 May 26:e8843. Epub 2020 May 26.

College of Veterinary Medicine, Hunan Agricultural University, Changsha, 410128, Hunan, China.

Rationale: Gelsemium elegans (G. elegans) is highly toxic to humans and rats but has insecticidal and growth-promoting effects on pigs and goats. However, the mechanisms behind the toxicity differences of G. Read More

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http://dx.doi.org/10.1002/rcm.8843DOI Listing

Metabolomics Reveals Altered Hepatic Bile Acids, Gut Microbiome Metabolites, and Cell Membrane Lipids Associated with Marginal Vitamin A Deficiency in a Mongolian Gerbil Model.

Mol Nutr Food Res 2020 May 26:e1901319. Epub 2020 May 26.

West Coast Metabolomics Center, University of California, Davis, CA, USA.

Scope: This study was designed to provide a broad evaluation of the impacts of vitamin A (VA) deficiency on hepatic metabolism in a gerbil model.

Methods And Results: After 28d of VA depletion, male Mongolian gerbils (Meriones unguiculatus) were randomly assigned to experimental diets for 28 d. Groups were fed a white maize-based diet with ∼50 μL cottonseed oil vehicle either alone (VA-, n = 10) or containing 40 μg retinyl acetate (VA+, n = 10) for 28 d. Read More

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http://dx.doi.org/10.1002/mnfr.201901319DOI Listing

AtPLATZ2 negatively regulates salt tolerance in Arabidopsis seedlings by directly suppressing the expression of the CBL4/SOS3 and CBL10/SCaBP8 genes.

J Exp Bot 2020 May 26. Epub 2020 May 26.

State Key Laboratory of Crop Biology, College of Life Sciences, Shandong Agricultural University, Tai'an, Shandong, P.R China.

Although the salt overly sensitive (SOS) pathway plays essential roles in conferring salt tolerance in Arabidopsis thaliana, the regulatory mechanism underlying SOS gene expression remains largely unclear. In this study, AtPLATZ2 was found to function as a direct transcriptional suppressor of CBL4/SOS3 and CBL10/SCaBP8 in the Arabidopsis salt stress response. Compared with wild-type (WT) plants, transgenic plants constitutively overexpressing AtPLATZ2 exhibited increased sensitivity to salt stress. Read More

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http://dx.doi.org/10.1093/jxb/eraa259DOI Listing

Cysteine protease RD21A regulated by E3 ligase SINAT4 is required for drought-induced resistance to Pseudomonas syringae in Arabidopsis.

J Exp Bot 2020 May 26. Epub 2020 May 26.

School of Plant and Environmental Sciences, Virginia Tech, Blacksburg, VA.

Plants can be simultaneously exposed to multiple stresses. The interplay of abiotic and biotic stresses may result in synergistic or antagonistic effects on plant development and health. Temporary drought stress can stimulate plant immunity; however, the molecular mechanism of drought-induced immunity is largely unknown. Read More

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http://dx.doi.org/10.1093/jxb/eraa255DOI Listing

Zn2+ dependent glyoxalase I plays the major role in methylglyoxal detoxification and salinity stress tolerance in plants.

PLoS One 2020 26;15(5):e0233493. Epub 2020 May 26.

Plant Molecular Biology Laboratory, Faculty of Life Sciences and Biotechnology, South Asian University, Chanakyapuri, New Delhi, India.

Glyoxalase pathway is the major pathway of methylglyoxal detoxification and is ubiquitously present in all organisms ranging from prokaryotes to eukaryotes. Glyoxalase I (GLYI) and Glyoxalase II (GLYII), the two core enzymes of this pathway work together to neutralize methylglyoxal (MG), a dicarbonyl molecule with detrimental cytotoxicity at higher concentrations. The first step towards the detoxification of MG is catalyzed by GLYI, a metalloenzyme that requires divalent metal ions (either Zn2+ as seen in eukaryotes or Ni2+ as in prokaryotes). Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0233493PLOS

Validation of canine uterine and testicular arteries for the functional characterisation of receptor-mediated contraction as a replacement for laboratory animal tissues in teaching.

PLoS One 2020 26;15(5):e0230516. Epub 2020 May 26.

Department of Veterinary Biosciences, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, University of Melbourne, Parkville, Victoria, Australia.

Teaching practicals for receptor physiology/pharmacology in medical and veterinary schools have involved the use of in vitro experiments using tissues from laboratory animals, which have been killed for isolated vascular strip or ring preparations. However, the use of scavenged tissues has been advocated to reduce animal use. Utilising discarded tissues from routine surgical procedures, such as canine neutering, has not previously been investigated. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0230516PLOS

De novo identification of toxicants that cause irreparable damage to parasitic nematode intestinal cells.

PLoS Negl Trop Dis 2020 May 26;14(5):e0007942. Epub 2020 May 26.

Division of Infectious Diseases, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America.

Efforts to identify new drugs for therapeutic and preventive treatments against parasitic nematodes have gained increasing interest with expanding pathogen omics databases and drug databases from which new anthelmintic compounds might be identified. Here, a novel approach focused on integrating a pan-Nematoda multi-omics data targeted to a specific nematode organ system (the intestinal tract) with evidence-based filtering and chemogenomic screening was undertaken. Based on de novo computational target prioritization of the 3,564 conserved intestine genes in A. Read More

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http://dx.doi.org/10.1371/journal.pntd.0007942DOI Listing

Isotope and chemical assessment of natural water in the Jaffna Peninsula in northern Sri Lanka for groundwater development aspects.

Isotopes Environ Health Stud 2020 May 26:1-15. Epub 2020 May 26.

Isotope Hydrology Section, Sri Lanka Atomic Energy Board (SLAEB), Orugodawatta, Sri Lanka.

The demand for fresh groundwater in the Jaffna peninsula in northern Sri Lanka, has been increasing as the only water source for domestic and agricultural needs. Isotopic and hydro-chemical assessment on groundwater recharge and quality was done with the objective of assisting groundwater management plans. Water samples were collected in pre and post monsoon periods for isotope analyses (H, O and H) and major ions. Read More

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http://dx.doi.org/10.1080/10256016.2020.1766457DOI Listing

Climate and land use interactively shape butterfly diversity in tropical rainforest and savanna ecosystems of southwestern China.

Insect Sci 2020 May 26. Epub 2020 May 26.

Department of Organismic and Evolutionary Biology, Museum of Comparative Zoology, Harvard University, Cambridge, MA, United States.

Human-induced habitat conversion and degradation, along with accelerating climatic change, have resulted in considerable global biodiversity loss. Nevertheless, how local ecological assemblages respond to the interplay between climate and land-use change remains poorly understood. Here, we examined the effects of climate and land-use interactions on butterfly diversity in different ecosystems of southwestern China. Read More

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http://dx.doi.org/10.1111/1744-7917.12824DOI Listing

Simplified Synthesis of Biomass Derived Si/C Composite as a Stable Anode Material for Lithium-Ion Batteries.

Chemistry 2020 May 26. Epub 2020 May 26.

Shandong University, School of Chemistry and Chemical Engineering, 27 Shanda Sth Rd, Jinan, Shandong, 250100, , 250100, Jinan, CHINA.

Synthesis of silicon/carbon (Si/C) by biomass resources enables the effective utilization of agricultural products in battery industries because of economical as well as environmental considerations. Herein, a simplified process was developed to synthesize Si/C from biomass, using low-cost agricultural by-products "rice husk (RH)" as a model. This process includes the calcination of RH for SiO2/C and the reduction of SiO2/C by Al in molten salts at a moderate temperature. Read More

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http://dx.doi.org/10.1002/chem.202000953DOI Listing

Localization shift of a sugar transporter contributes to phloem unloading in sweet watermelons.

New Phytol 2020 May 26. Epub 2020 May 26.

National Watermelon and Melon Improvement Center, Beijing Academy of Agricultural and Forestry Sciences, Key Laboratory of Biology and Genetic Improvement of Horticultural Crops (North China), Beijing Key Laboratory of Vegetable Germplasm Improvement, Beijing, 100097, China.

Unloading sugar from sink phloem by transporters is complex and much remains to be understood in watermelons. Here, we report a novel vacuolar sugar transporter (ClVST1) identified through map-based cloning and association study, whose expression in fruit phloem is associated with accumulation of sucrose (Suc) in watermelon fruit. ClVST1 knockout lines show decreased sugar content and total biomass, whereas overexpression of ClVST1 increase Suc content. Read More

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http://dx.doi.org/10.1111/nph.16659DOI Listing

Native de novo structural determinations of non-canonical nucleic acid motifs by X-ray crystallography at long wavelengths.

Nucleic Acids Res 2020 May 26. Epub 2020 May 26.

State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, China.

Obtaining phase information remains a formidable challenge for nucleic acid structure determination. The introduction of an X-ray synchrotron beamline designed to be tunable to long wavelengths at Diamond Light Source has opened the possibility to native de novo structure determinations by the use of intrinsic scattering elements. This provides opportunities to overcome the limitations of introducing modifying nucleotides, often required to derive phasing information. Read More

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http://dx.doi.org/10.1093/nar/gkaa439DOI Listing

Functional analysis of 4-coumarate: CoA ligase from Dryopteris fragrans in transgenic tobacco enhances lignin and flavonoids.

Genet Mol Biol 2020 20;43(2):e20180355. Epub 2020 May 20.

Qiqihar University, College of Life Sciences and Agriculture and Forestry, Qiqihar, China.

4-Coumaric acid: coenzyme A ligase (4CL) is a key enzyme in the phenylpropanoid metabolic pathway that regulates the biosynthesis of lignin and flavonoids. Therefore, the study of 4CL is important to explore the accumulation and regulation of metabolites. This study investigated the role that the 4CL2 gene from Dryopteris fragrans (Df4CL2) plays in the metabolite synthesis. Read More

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http://dx.doi.org/10.1590/1678-4685-GMB-2018-0355DOI Listing

Identity and Pathogenicity of Fungi Associated with Crown and Root Rot of Dryland Winter Wheat in Azerbaijan.

Plant Dis 2020 May 26:PDIS08191799RE. Epub 2020 May 26.

International Maize and Wheat Improvement Centre (CIMMYT) P.O. Box. 39 Emek, Ankara, Turkey.

A comprehensive survey was performed to assess fungal populations associated with crown and root rot of wheat throughout the main wheat-growing areas of Azerbaijan. Samples were taken from 76 fields; 630 fungal strains were isolated, identified, and evaluated for pathogenicity. The identification was conducted with morphological and molecular tools such as species-specific PCR and DNA sequencing of the internal transcribed spacer (ITS) and -α (-α) loci. Read More

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http://dx.doi.org/10.1094/PDIS-08-19-1799-REDOI Listing