2,091 results match your criteria Aging Clinical and Experimental Research[Journal]


The effect of ageing on shear wave elastography muscle stiffness in adults.

Aging Clin Exp Res 2019 Feb 14. Epub 2019 Feb 14.

Chapel Allerton Hospital, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.

Background: Skeletal muscle undergoes structural changes with ageing which may alter its biomechanical properties. Shear wave elastography (SWE) may detect these changes by measuring muscle stiffness.

Aims: To investigate muscle stiffness in healthy young, middle-aged and elderly cohorts using SWE and correlate it with muscle strength and mass. Read More

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http://link.springer.com/10.1007/s40520-019-01139-0
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http://dx.doi.org/10.1007/s40520-019-01139-0DOI Listing
February 2019
1 Read

Waist circumference or sarcopenic obesity: which is more predictive?

Aging Clin Exp Res 2019 Feb 13. Epub 2019 Feb 13.

Division of Geriatrics, Department of Internal Medicine, Faculty of Medicine, Hacettepe University, Ankara, Turkey.

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http://dx.doi.org/10.1007/s40520-019-01144-3DOI Listing
February 2019

Multi-sensory training and wrist fractures: a randomized, controlled trial.

Aging Clin Exp Res 2019 Feb 11. Epub 2019 Feb 11.

Faculty of Medicine, University of Iceland, Reykjavik, Iceland.

Background: Asymmetric vestibular function, decreased plantar sensation, postural control and functional ability have been associated with fall-related wrist fractures.

Objective: To investigate whether multi-sensory training (MST) improves postural control, vestibular function, foot sensation and functional ability among people with fall-related wrist fractures compared to wrist stabilization training (WT).

Methods: This was an assessor-blinded, randomized controlled trial. Read More

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http://dx.doi.org/10.1007/s40520-019-01143-4DOI Listing
February 2019

Cost-effectiveness evaluation of glucosamine for osteoarthritis based on simulation of individual patient data obtained from aggregated data in published studies.

Aging Clin Exp Res 2019 Feb 12. Epub 2019 Feb 12.

Department of Public Health, Epidemiology and Health Economics, WHO Collaborating Centre for Public Health Aspects of Musculo-Skeletal Health and Ageing, University of Liège, 4000, Liège, Belgium.

Background: The economic evaluation of treatments usually requires access to individual patient data, which is difficult to obtain. Moreover, in osteoarthritis, health utility scores are unavailable and can be assessed only using a validated equation model based on various clinical data. We aimed to develop and validate a methodology to simulate individual health utility scores from aggregated clinical data available in published studies to calculate the cost-effectiveness of different glucosamine preparations (i. Read More

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http://dx.doi.org/10.1007/s40520-019-01138-1DOI Listing
February 2019
1 Read

Efficacy of different types of exercises on global cognition in adults with mild cognitive impairment: a network meta-analysis.

Aging Clin Exp Res 2019 Feb 9. Epub 2019 Feb 9.

School of Nursing, Jilin University, 965 Xinjiang Street, Changchun, 130021, China.

Objective: To compare the efficacy of different types of exercises on global cognition in adults with mild cognitive impairment.

Methods: We systematically searched six databases from their inception to December 14, 2018, for randomized controlled trials evaluating the efficacy of exercise on global cognition in adults with mild cognitive impairment. For the included studies, the mean changes in global cognition from baseline to endpoint were analyzed. Read More

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http://link.springer.com/10.1007/s40520-019-01142-5
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http://dx.doi.org/10.1007/s40520-019-01142-5DOI Listing
February 2019
3 Reads

Calabria: a successful experience implementing Herpes Zoster vaccination strategies.

Authors:
Sandro Giuffrida

Aging Clin Exp Res 2019 Feb 8. Epub 2019 Feb 8.

Azienda Sanitaria Provinciale di Reggio Calabria, Reggio, Italy.

Recently, the National Immunization Plan (NIP) in Italy has highlighted the importance of immunization practices also for adults, including vaccinations against influenza, Pneumococcus (PNO) and HZ. In response to the NIP, the Calabria region decided to offer HZ vaccination to the two cohorts of 65- and 70-year-old subjects. We at the Reggio Calabria Local Health Services, concentrated our efforts on addressing all the above-mentioned shortcomings and, as a first measure, we addressed the convenience problem by scheduling the HZ vaccine administration during the same visit as the pneumococcal vaccination (PCV13 vaccine). Read More

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http://dx.doi.org/10.1007/s40520-019-01145-2DOI Listing
February 2019
1 Read

Nutritional influence on bone: role of gut microbiota.

Authors:
René Rizzoli

Aging Clin Exp Res 2019 Feb 1. Epub 2019 Feb 1.

Service of Bone Diseases, Geneva University Hospitals and Faculty of Medicine, 1211, Geneva 14, Switzerland.

Gut microbiota (GM) located within the intestinal tract lumen comprises the largest number of cells (1014) in the human body. The gut microbiome refers to the collection of genomes and genes present in gut microbiota. GM can vary according to age, sex, genetic background, immune status, geography, diet, prebiotics, which are non-digestible fibers metabolized in the distal part of the gastrointestinal tract, probiotics, which are micro-organisms conferring a health benefit on the host when administered in adequate amounts, living conditions, diseases and drugs. Read More

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http://dx.doi.org/10.1007/s40520-019-01131-8DOI Listing
February 2019
2 Reads

Relationship between blood pressure variability and cognitive function in geriatric hypertensive patients with well-controlled blood pressure.

Aging Clin Exp Res 2019 Feb 1. Epub 2019 Feb 1.

Department of Internal Medicine, Biruni University Faculty of Medicine, Istanbul, Turkey.

Background: Hypertension is an important risk factor for cardiovascular diseases and cognitive function. Blood pressure (BP) variability has been associated with cognitive dysfunction, but data are sparse regarding the relationship between BP variability and cognitive function in geriatric patients with well-controlled BP.

Aim: The aim of this study was to demonstrate the relationship between blood pressure variability and cognitive functions in geriatric hypertensive patients with well-controlled BP. Read More

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http://dx.doi.org/10.1007/s40520-019-01141-6DOI Listing
February 2019
2 Reads

Biochemical markers of inflammation are associated with increased mortality in hip fracture patients: the Bispebjerg Hip Fracture Biobank.

Aging Clin Exp Res 2019 Feb 1. Epub 2019 Feb 1.

Department of Clinical Biochemistry, Hvidovre Hospital, Kettegård Alle 30, 2650, Hvidovre, Denmark.

Purpose: The purpose of this study was to examine the possible association between mortality following a hip fracture and known biochemical markers of inflammation.

Methods: The study population was identified using two local databases from Bispebjerg Hospital (Copenhagen, Denmark): the Hip Fracture Database containing all patients admitted to the hospital with a fractured hip from 1996 to 2012 and the Hip Fracture Biobank, containing whole blood, serum and plasma taken in relation to admission on a subgroup of patients from the Hip Fracture Database, consecutively collected over a period of 2.5 years from 2008 to 2011. Read More

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http://dx.doi.org/10.1007/s40520-019-01140-7DOI Listing
February 2019
1 Read

Individual and cumulative association of commonly used biomarkers on frailty: a cross-sectional analysis of the Mexican Health and Aging Study.

Aging Clin Exp Res 2019 Jan 31. Epub 2019 Jan 31.

Instituto Nacional de Geriatría, Periférico Sur 2767, colonia San Jerónimo Lídice, delegación Magdalena Contreras, 10200, Mexico, Mexico.

Frailty has been recognized as a common condition in older adults, however, there is scarce information on the association between frailty and commonly used biomarkers. The aim of this study was to assess the individual and cumulative association of biomarkers with frailty status. This is a cross-sectional analysis of the 2012 wave of the Mexican Health and Aging Study. Read More

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http://dx.doi.org/10.1007/s40520-019-01127-4DOI Listing
January 2019

The role of parathyroid hormone (PTH) and vitamin D in falls and hip fracture type.

Aging Clin Exp Res 2019 Jan 30. Epub 2019 Jan 30.

First Department of Orthopaedics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.

Background: Fragility fractures of the hip are associated with high morbidity and mortality, and represent a rather devastating consequence of osteoporosis. Hip fractures are traditionally investigated as a whole, although it has been recently implied that distinct pathogenic mechanisms may lead either to trochanteric or subcapital fractures.

Aims: To investigate whether differences exist by hip fracture type with respect to serum 25(OH)D (vitamin D) and parathyroid hormone (PTH) levels, in addition to epidemiological and demographic data, including history of falls. Read More

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http://dx.doi.org/10.1007/s40520-019-01132-7DOI Listing
January 2019

Association between serum uric acid levels and coronary artery disease in different age and gender: a cross-sectional study.

Aging Clin Exp Res 2019 Jan 29. Epub 2019 Jan 29.

Department of Geriatric Cardiology, The First Affiliated Hospital of China Medical University, No. 155 Nanjing North Street, Heping Ward, Shenyang, 110001, China.

Background: The association between uric acid (UA) and coronary artery disease (CAD) was controversial. It was still unclear how the UA level changes with age and gender.

Aims: To confirm the relationship between the change of UA with age and gender and CAD, especially in elderly people. Read More

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http://dx.doi.org/10.1007/s40520-019-01137-2DOI Listing
January 2019
1 Read

Needs of persons with dementia and their family caregivers in dementia cafés.

Aging Clin Exp Res 2019 Jan 29. Epub 2019 Jan 29.

Department of Urban Engineering, Graduate School of Engineering, University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.

Background And Aims: Several studies have shown the effectiveness and diversity of dementia cafés, whereas there are few published articles in academic research focusing on what persons with dementia and their family caregivers need and whether the services provided satisfy their needs. This study aimed to identify the needs of persons with dementia and their family caregivers participating in dementia cafés in Japan.

Methods: Interviews and participant observations were conducted in nine dementia cafés. Read More

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http://dx.doi.org/10.1007/s40520-019-01129-2DOI Listing
January 2019

Efficacy and safety of endoscopic submucosal dissection for gastric epithelial neoplasia in elderly patients aged 80 years and older.

Aging Clin Exp Res 2019 Jan 29. Epub 2019 Jan 29.

Division of Gastroenterology, Department of Internal Medicine, National Health Insurance Service Ilsan Hospital, 100 Ilsan-ro Ilsan-donggu, Goyang-si, 10444, South Korea.

Background: Endoscopic submucosal dissection (ESD) has been widely used in gastric tumor as a minimally invasive treatment. The efficacy and safety of ESD is still unclear in the elderly who have high frequency comorbidities. The aim of this study is to evaluate the efficacy and safety of ESD for gastric epithelial neoplasia in patients aged 80 years and older. Read More

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http://dx.doi.org/10.1007/s40520-019-01133-6DOI Listing
January 2019

Vitamin B12-fortified toothpaste improves vitamin status in elderly people: a randomized, double-blind, placebo-controlled study.

Aging Clin Exp Res 2019 Jan 24. Epub 2019 Jan 24.

Department of Clinical Chemistry and Laboratory Medicine, Saarland University Hospital, Building 57, 66421, Homburg, Saar, Germany.

Background: Elderly people are at risk for vitamin B12 deficiency.

Aims: We studied the ability of vitamin B12-enriched toothpaste vs. placebo to increase vitamin B12 status in elderly subjects. Read More

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http://dx.doi.org/10.1007/s40520-019-01125-6DOI Listing
January 2019
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Dietary strategies for mitigating osteosarcopenia in older adults: a narrative review.

Aging Clin Exp Res 2019 Jan 23. Epub 2019 Jan 23.

Geriatrics Division, Department of Medicine-DIMED, University of Padova, Via Giustiniani 2, Padua, Italy.

The synchronic loss of bone mineral density and decrease in muscle mass, strength, and function defines the scenario of osteosarcopenia, which is associated with an increased risk of falls and fractures in older adults. An important role in preventing muscle and bone loss is played by nutritional factors, in particular the intake of proteins, calcium, magnesium and vitamin D. This review summarizes the available literature concerning the influence of protein intake and supplementation (vitamin D, Ca, Mg, branched-chain amino acids) on the decline of musculoskeletal integrity in healthy older adults. Read More

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http://dx.doi.org/10.1007/s40520-019-01130-9DOI Listing
January 2019
1 Read

Diabetes mellitus, frailty and prognosis in very elderly patients with acute coronary syndromes.

Aging Clin Exp Res 2019 Jan 22. Epub 2019 Jan 22.

Cardiology Department, Bellvitge University Hospital, Feixa Llarga s/n, L'Hospitalet de Llobregat, 08907, Barcelona, Spain.

Background: The magnitude of the association between diabetes (DM) and outcomes in elderly patients with acute coronary syndromes (ACS) is controversial. No study assessed the prognostic impact of DM according to frailty status in these patients.

Methods: The LONGEVO-SCA registry included unselected ACS patients aged ≥ 80 years. Read More

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http://dx.doi.org/10.1007/s40520-018-01118-xDOI Listing
January 2019
1 Read

Sarcopenia and swallowing disorders in older people.

Aging Clin Exp Res 2019 Jan 22. Epub 2019 Jan 22.

Geriatric Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Pace 9, 20122, Milan, Italy.

Aging is accompanied by several changes which may affect swallowing function. The beginning of these changes, termed presbyphagia, still captures a preserved swallowing function, although burdened by the consequences of the physiological aging process. Several stressors (including diseases and medications) can easily trigger the disruption of this (increasingly weak) equilibrium and lead to overt dysphagia. Read More

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http://link.springer.com/10.1007/s40520-019-01128-3
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http://dx.doi.org/10.1007/s40520-019-01128-3DOI Listing
January 2019
7 Reads

Perception of parks and trails as mobility facilitators and transportation walking in older adults: a study using digital geographical maps.

Aging Clin Exp Res 2019 Jan 21. Epub 2019 Jan 21.

Gerontology Research Center, Faculty of Sport and Health Sciences, University of Jyväskylä, 40014, Jyväskylä, Finland.

Background: Transportation walking represents a promising target for physical activity promotion in older adults. Perceived characteristics of the neighbourhood physical environment may affect older adults' choice of transportation mode for a routine activity such as walking to the grocery store.

Aims: To (1) evaluate associations between older adults' perception of parks and trails as outdoor mobility facilitators and transportation walking, specifically to the grocery store; and (2) explore whether the spatial relationship between people's home, perceived facilitator and store was relevant for their transportation choice. Read More

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http://dx.doi.org/10.1007/s40520-018-01115-0DOI Listing
January 2019

The effects of same-session combined exercise training on cardiorespiratory and functional fitness in older adults: a systematic review and meta-analysis.

Aging Clin Exp Res 2019 Jan 19. Epub 2019 Jan 19.

School of Health and Social Care, Teesside University, Middlesbrough, UK.

Endurance and strength training are effective strategies for counteracting age-associated reductions in physical performance in older adults, with a combination of both exercise modes recommended to maximise potential fitness benefits. This meta-analysis sought to quantify the effects of same-session combined endurance and strength training on fitness in adults aged over 50 years. Five electronic databases were searched with studies required to include one of the following outcome measures: VO, 6-min walk test (6MWT), 8-ft timed up-and-go (TUG), and 30-s chair stand. Read More

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http://dx.doi.org/10.1007/s40520-019-01124-7DOI Listing
January 2019
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Behavioral and cognitive markers of mild cognitive impairment: diagnostic value of saccadic eye movements and Simon task.

Aging Clin Exp Res 2019 Jan 18. Epub 2019 Jan 18.

Iranian Research Center on Aging, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.

Background: Mild Cognitive Impairment (MCI) has been considered as a prodromal stage of Alzheimer disease (AD). Subtle changes in specific aspects of executive function like inhibitory control have been found in MCI.

Aims: We examined attentional and inhibitory control with the aim to distinguish between amnestic MCI patients and healthy controls. Read More

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http://dx.doi.org/10.1007/s40520-019-01121-wDOI Listing
January 2019
3 Reads
1.138 Impact Factor

Differential impact of endurance, strength, or combined training on quality of life and plasma serotonin in healthy older women.

Aging Clin Exp Res 2019 Jan 18. Epub 2019 Jan 18.

National Institute of Science and Technology for Translational Medicine (INCT-TM), Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq), Brasília, Brazil.

Aging is associated with a progressive decline in physical and neurophysiological functions, and some studies suggest that cerebral serotonin is decreased in older adults. These factors contribute to reduced ability to perform daily activities, influencing quality of life (QoL). Regular physical activity has demonstrated important benefits in reversing ageing effects; however, little is known whether different training protocols might induce differential effects on QoL. Read More

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http://link.springer.com/10.1007/s40520-019-01120-x
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http://dx.doi.org/10.1007/s40520-019-01120-xDOI Listing
January 2019
6 Reads

Consistency and test-retest reliability of stepping tests designed to measure self-perceived and actual physical stepping ability in older adults.

Aging Clin Exp Res 2019 Jan 16. Epub 2019 Jan 16.

Department of Human Movement Sciences, Vrije Universiteit Amsterdam, Research Institute Amsterdam Movement Sciences, Van der Boechorststraat 9, 1081 BT, Amsterdam, The Netherlands.

Background: Older adults with an incorrect perception of their physical abilities may fall more often, suggesting a need for tests to quantify self-perceived and actual abilities.

Aims: To determine between-test consistency and test-retest reliability of three tests that measure self-perceived and actual stepping ability in older adults.

Methods: Older adults performed three stepping tests, covering high (bar test) and far steps (river and step tests). Read More

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http://dx.doi.org/10.1007/s40520-018-01112-3DOI Listing
January 2019
1 Read

Soluble TREM1 concentrations are increased and positively correlated with total tau levels in the plasma of patients with Alzheimer's disease.

Aging Clin Exp Res 2019 Jan 14. Epub 2019 Jan 14.

Department of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing, People's Republic of China.

Background/aims: Recently, we showed that triggering receptor expressed on myeloid cells 1 (TREM1) was involved in the pathogenesis of Alzheimer's disease (AD) since it modulated microglial phagocytic functions and thus affected amyloid-β clearance in the brain. Interestingly, a soluble form of TREM1 (sTREM1) can be detected in the plasma of human. To date, whether sTREM1 concentrations were altered in the plasma under AD context remained unclear. Read More

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http://dx.doi.org/10.1007/s40520-019-01122-9DOI Listing
January 2019
4 Reads

Nursing home staff members' knowledge, experience and attitudes regarding advance care planning: a cross-sectional study involving 12 Italian nursing homes.

Aging Clin Exp Res 2019 Jan 14. Epub 2019 Jan 14.

Department of Medical and Surgical Sciences, DIMEC, University of Bologna, Via Irnerio, 49, Bologna, 40126, Italy.

Background: Advance care planning may be beneficial for nursing home residents, but its implementation is suboptimal in several countries.

Aims: To investigate knowledge of, attitudes towards, and experience with advance care planning of nursing home staff members in Italy.

Methods: Cross-sectional survey involving all healthcare professionals working in 12 Italian nursing homes. Read More

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http://dx.doi.org/10.1007/s40520-018-01110-5DOI Listing
January 2019
5 Reads

A case of right Alzheimer's disease.

Aging Clin Exp Res 2019 Jan 10. Epub 2019 Jan 10.

Geriatric Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Via Alfonso Lamarmora 5, 20122, Milan, Italy.

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http://dx.doi.org/10.1007/s40520-018-01116-zDOI Listing
January 2019
5 Reads

Inappropriate medication use in hospitalised oldest old patients across transitions of care.

Aging Clin Exp Res 2019 Jan 10. Epub 2019 Jan 10.

The Royal Melbourne Hospital, Royal Parade, Parkville, Victoria, 3052, Australia.

Background: Oldest old patients aged 85 years and over are at risk of experiencing potentially inappropriate medications (PIMs) and potential prescribing omissions (PPOs) across transitions of care. Geriatricians also face enormous challenges in prescribing medications for these patients.

Methods: A mixed-methods, sequential explanatory design was undertaken of electronic medical records and semi-structured interviews with geriatricians at a public teaching hospital. Read More

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http://link.springer.com/10.1007/s40520-018-01114-1
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http://dx.doi.org/10.1007/s40520-018-01114-1DOI Listing
January 2019
5 Reads

Presbyesophagus presented with chronic intermittent dysphagia.

Aging Clin Exp Res 2019 Jan 10. Epub 2019 Jan 10.

Department of Internal Medicine, Abington-Jefferson Hospital, 1200 Old York Road, Abington, PA, 19001, USA.

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http://dx.doi.org/10.1007/s40520-018-1080-0DOI Listing
January 2019
1 Read

Associations between sleep and obesity indices in older adults: results from the HELIAD study.

Aging Clin Exp Res 2019 Jan 9. Epub 2019 Jan 9.

Department of Nutrition and Dietetics, Harokopio University, Athens, Greece.

Background: Short sleep duration and low sleep quality are negatively associated with obesity in young adults, but in older people the results are inconsistent.

Aims: The aim of the present study was to examine the associations between sleep duration and quality with both body mass index (BMI) and waist circumference (WC) and to investigate sex- and age-specific associations in a population-representative cohort of older adults.

Methods: 1781 participants ≥ 65 years old from the HELIAD study were included. Read More

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http://link.springer.com/10.1007/s40520-018-01113-2
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http://dx.doi.org/10.1007/s40520-018-01113-2DOI Listing
January 2019
16 Reads

Old age is a positive modifier of renal outcome in Taiwanese patients with stages 3-5 chronic kidney disease.

Aging Clin Exp Res 2019 Jan 9. Epub 2019 Jan 9.

Renal Division, Department of Internal Medicine, College of Medicine, National Taiwan University Hospital, National Taiwan University, No. 7, Chung Shan S. Rd., Zhongzheng Dist, Taipei, 10002, Taiwan.

Background: The incidence of end-stage renal disease (ESRD) is increasing in elderly patients with chronic kidney disease (CKD). This contradicts the general notion that elderly people are more likely to die than to ever reach ESRD. And racial disparity in relation to age on kidney disease outcomes has always been a subject of research interest. Read More

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http://dx.doi.org/10.1007/s40520-018-01117-yDOI Listing
January 2019
1 Read

Does the identification of seniors at risk (ISAR) score effectively select geriatric patients on emergency admission?

Aging Clin Exp Res 2019 Jan 8. Epub 2019 Jan 8.

Ageing Clinical Research, Department of Internal Medicine II, University Hospital Cologne, Cologne, North Rhine Westphalia, Germany.

The number of older patients admitted to emergency departments (ED) increases continuously. The Identification of Seniors at Risk (ISAR) score is currently recommended to screen patients in German ED, but its appropriateness is being criticized. ISAR scores and clinical characteristics from 98 emergency admissions (EA), 80 from acute geriatrics (AG) and 89 from a geriatric rehabilitation (GR) unit were compared retrospectively. Read More

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http://link.springer.com/10.1007/s40520-018-1105-8
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http://dx.doi.org/10.1007/s40520-018-1105-8DOI Listing
January 2019
9 Reads

A nurse-led model of care within an emergency department reduces representation rates for frail aged care residents.

Aging Clin Exp Res 2019 Jan 7. Epub 2019 Jan 7.

Mater/UQ Centre for Integrated Care and Innovation, Mater Health Services, Level 2 Aubigny Place, Raymond Tce, South Brisbane, QLD, 4101, Australia.

Background: Hospital Emergency Departments (EDs) experience high presentation rates from older adults residing in Aged Care Facilities (ACFs), yet very few intervention studies have addressed the care needs of this population group. We designed and implemented a nurse-led model of care for older adults from ACFs, and determined its impact on patient outcomes.

Methods: This 12-month pre-post intervention study was conducted during 2013-2014, with follow-up during 2015-2016. Read More

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http://dx.doi.org/10.1007/s40520-018-1101-zDOI Listing
January 2019
1 Read
1.138 Impact Factor

Effectiveness of a community care management program for multimorbid elderly patients with heart failure in the Veneto Region.

Aging Clin Exp Res 2019 Feb 7;31(2):241-247. Epub 2019 Jan 7.

Epidemiological Service of the Veneto Region, Azienda Zero, 35131, Padua, PD, Italy.

Background: The rapidly growing population of elderly subjects with multimorbidity is at risk of receiving fragmented and uncoordinated care, and have frequent hospitalizations and emergency room (ER) visits.

Aims: The study aims to describe the impact of a care management program (CMP) developed in the Veneto region (Northeastern Italy) for patients affected by chronic heart failure (CHF) and multimorbidity.

Methods: The CMP was provided to 330 patients > 65 years suffering from CHF and multimorbidity. Read More

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http://dx.doi.org/10.1007/s40520-018-1102-yDOI Listing
February 2019
1 Read

Low skeletal muscle mass and radiographic osteoarthritis in knee, hip, and lumbar spine: a cross-sectional study.

Aging Clin Exp Res 2019 Jan 7. Epub 2019 Jan 7.

Department of Rehabilitation Medicine, Seoul National University College of Medicine, SMG-SNU Boramae Medical Center, Seoul, Republic of Korea.

Background: Although several studies have shown that low skeletal muscle mass is correlated with knee osteoarthritis, no studies have investigated the correlation between skeletal muscle mass and hip and lumbar spine osteoarthritis (OA).

Aim: This study aimed to delineate the relationship between low skeletal muscle mass and radiographic OA (ROA) of the knee, hip, and lumbar spine.

Methods: This is a cross-sectional study using the public data obtained from the Fifth Korean National Health and Nutrition Examination Survey (2010-2011). Read More

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http://link.springer.com/10.1007/s40520-018-1108-5
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http://dx.doi.org/10.1007/s40520-018-1108-5DOI Listing
January 2019
9 Reads

Executive summary of European guidance for the diagnosis and management of osteoporosis in postmenopausal women.

Aging Clin Exp Res 2019 Jan 5;31(1):15-17. Epub 2019 Jan 5.

Chair for Biomarkers of Chronic Diseses, Department of Biochemistry, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia.

A guidance on the assessment and treatment of postmenopausal women at risk from fractures due to osteoporosis was recently published in Osteoporosis International as a joint effort of the International Osteoporosis Foundation and European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (Kanis et al. Osteoporos Int, https://doi.org/10. Read More

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http://dx.doi.org/10.1007/s40520-018-1109-4DOI Listing
January 2019
3 Reads

Patients' preferences for osteoarthritis treatment: the value of stated-preference studies.

Aging Clin Exp Res 2019 Jan 4;31(1):1-3. Epub 2019 Jan 4.

Prince Mutaib Chair for Biomarkers of Osteoporosis, Biochemistry Department, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia.

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http://dx.doi.org/10.1007/s40520-018-1098-3DOI Listing
January 2019
2 Reads

Gender differences and burden of chronic conditions: impact on quality of life among the elderly in Taiwan.

Aging Clin Exp Res 2019 Jan 2. Epub 2019 Jan 2.

Department of Nursing, Mackay Medical College, No. 46, Sec. 3, Zhongzheng Road, New Taipei City, Sanzhi District, 252, Taiwan.

Background: Multiple chronic conditions affect people's health-related quality of life (QoL) and the distributions of the conditions may differ between genders. Our goal was to examine gender differences in chronic conditions and QoL among community-living elderly in Taiwan and to examine whether differences in QoL between genders, if present, were attributable to the distribution of chronic conditions.

Methods: We used data from the Nutrition and Health Survey in Taiwan (NAHSIT, 2005-2008), which interviewed a representative sample of the Taiwanese population. Read More

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http://dx.doi.org/10.1007/s40520-018-1099-2DOI Listing
January 2019
1 Read

Beyond the gait: a useful approach in assessing motor performance in old people.

Aging Clin Exp Res 2019 Feb 2;31(2):291-292. Epub 2019 Jan 2.

IRCCS Fondazione Don Carlo Gnocchi, Piazzale Morandi 6, 20121, Milan, Italy.

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http://dx.doi.org/10.1007/s40520-018-1103-xDOI Listing
February 2019
1 Read
1.138 Impact Factor

Study protocol of a randomised controlled trial to examine the impact of a complex intervention in pre-frail older adults.

Aging Clin Exp Res 2019 Jan 2. Epub 2019 Jan 2.

Department of Geriatric Medicine, University of Auckland, Auckland, New Zealand.

Background: Frailty is a multidimensional geriatric syndrome associated with functional loss. The Senior Chef (SC, nutrition) and SAYGO (strength and balance exercise) programmes are well accepted among older adults but the impact of each, or a combination of both, on the frailty syndrome in pre-frail older adults is unknown.

Aims: To determine the effectiveness and cost-effectiveness of a complex intervention consisting of the SC and/or SAYGO programmes to prevent progression of frailty in pre-frail older adults. Read More

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http://dx.doi.org/10.1007/s40520-018-1106-7DOI Listing
January 2019
2 Reads

Effect of a mixed-exercise program on physical capacity and sedentary behavior in older adults during cancer treatments.

Aging Clin Exp Res 2019 Jan 2. Epub 2019 Jan 2.

Faculty of Physical Activity Sciences, University of Sherbrooke, 2500, boul. de l'Université, Sherbrooke, QC, J1K 2R1, Canada.

Background: Aging, cancer and its treatment all contribute to increase the risk of deconditioning and sedentary behaviors. Mixed exercise is recognized to counteract the effects of aging and deconditioning as well as improving physical capacity during cancer treatment in adults.

Aims: To determine the impact of a mixed exercise program (MXEP) to improve physical capacity and decrease sedentary behavior time (SBT) in older adults during cancer treatment. Read More

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http://dx.doi.org/10.1007/s40520-018-1097-4DOI Listing
January 2019
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The association between apathy, decline in physical performance, and falls in older persons.

Aging Clin Exp Res 2019 Jan 2. Epub 2019 Jan 2.

Department of Internal Medicine, Geriatrics, Academic Medical Centre, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.

Background: Symptoms of apathy are common in older persons. Negative effects on physical performance and fall risk are plausible, considering the pathophysiology of apathy. However, literature is scarce. Read More

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http://link.springer.com/10.1007/s40520-018-1096-5
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http://dx.doi.org/10.1007/s40520-018-1096-5DOI Listing
January 2019
2 Reads

Midlife predictors of active and healthy aging (AHA) among older businessmen.

Aging Clin Exp Res 2019 Feb 24;31(2):225-231. Epub 2018 Dec 24.

Clinicum, and Helsinki University Hospital, University of Helsinki, Helsinki, Finland.

Background: Active and healthy aging (AHA) is an important phenomenon in aging societies.

Aims: Our aim was to investigate midlife predictors of AHA in a socioeconomically homogenous male cohort.

Methods: In 2010, AHA was defined in the Helsinki Businessmen Study (men born in 1919-1934) with six criteria: (1) being alive, (2) responding to the mailed survey, (3) no reported cognitive problems, (4) feeling of happiness, (5) no difficulties in activities of daily living (ADL), and (6) no significant chronic diseases. Read More

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http://dx.doi.org/10.1007/s40520-018-1100-0DOI Listing
February 2019
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Assessment of health literacy among older Finns.

Aging Clin Exp Res 2018 Dec 21. Epub 2018 Dec 21.

Gerontology Research Center, Faculty of Sport and Health Sciences, University of Jyväskylä, P.O. Box 35, 40014, Jyvaskyla, Finland.

Aims: This study examined the feasibility of the HLS-EU-Q16 (in Finnish) for use among older Finns and whether the health literacy score correlates with indicators of health and functioning.

Methods: To determine the feasibility of the instrument, we first conducted a focus group discussion with nine participants. For the quantitative analyses, we used data from the AGNES cohort study, collected between October 2017 and April 2018 at the University of Jyväskylä in Finland. Read More

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http://dx.doi.org/10.1007/s40520-018-1104-9DOI Listing
December 2018
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Can physical and cognitive training based on episodic memory be combined in a new protocol for daily training?

Aging Clin Exp Res 2018 Dec 19. Epub 2018 Dec 19.

The BioRobotics Institute, Scuola Superiore Sant' Anna, Viale Rinaldo Piaggio 34, Pontedera, 56025, Pisa, Italy.

Background: Cognitive training (CT) is defined as guided practice on a set of standard tasks designed to stimulate particular cognitive functions. Recent studies have shown that physical exercise is beneficial for cognitive activity in older adults and patients with degenerative diseases.

Aims: The main objective of the present study is to create a new cognitive tool able to provide training for cognitive functions that take advantage of the physical activity involved in the execution of the task. Read More

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http://dx.doi.org/10.1007/s40520-018-1107-6DOI Listing
December 2018
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Effects of interval walking training compared to normal walking training on cognitive function and arterial function in older adults: a randomized controlled trial.

Aging Clin Exp Res 2018 Dec 18. Epub 2018 Dec 18.

Center for Fundamental Education, Teikyo University of Science, Tokyo, Japan.

Purpose: This study investigated whether interval walking training (IWT) improves cognitive function and arterial function in older adults.

Methods: A total of 68 older adults registered in clinical trials (mean age ± standard deviation, 70 ± 4 years) were randomly assigned to two groups: one group performed IWT (n = 34), and the other performed normal walking training (NWT, n = 34). Participants in the IWT group performed five or more sets of low-intensity walking (duration: 3 min per set; peak aerobic capacity for walking: 40%) followed by high-intensity walking (duration: 3 min per set; peak aerobic capacity for walking: > 70%). Read More

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http://dx.doi.org/10.1007/s40520-018-1093-8DOI Listing
December 2018
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Clinical examination of peripheral arterial disease and ankle-brachial index in a nationwide cohort of older subjects: practical implications.

Aging Clin Exp Res 2018 Dec 17. Epub 2018 Dec 17.

The Department of Internal Medicine and Gerontology, Faculty of Medicine, Jagiellonian University Medical College, Ul. Śniadeckich 10, 31-531, Kraków, Poland.

Background: Prevalence of peripheral arterial disease increases with age and is related to increased morbidity and mortality. The clinical diagnosis includes the measurement of ankle-brachial index (ABI).

Aims: To check the prevalence of abnormal ABI, and the value of physical examination of arterial system in detection of ABI < 0. Read More

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http://dx.doi.org/10.1007/s40520-018-1095-6DOI Listing
December 2018
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Cystatin C and creatinine-based eGFR levels and their correlation to long-term morbidity and mortality in older adults.

Aging Clin Exp Res 2018 Dec 17. Epub 2018 Dec 17.

Department of Geriatrics, Skåne University Hospital, Jan Waldenströms gata 35, 20502, Malmö, Sweden.

Background: The prevailing diagnostic criteria for CKD are age-independent, but have been challenged in light of the eGFR decline associated with normal aging. The stages of CKD communicate magnitude of risk of ESRD, cardiovascular morbidity, and mortality.

Aims: This study aims to provide more insight into the morbidity and mortality associated with eGFR levels corresponding to the current CKD stages in older adults. Read More

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http://dx.doi.org/10.1007/s40520-018-1091-xDOI Listing
December 2018
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Do frailty and comorbidity indices improve risk prediction of 28-day ED reattendance? Reanalysis of an ED discharge nomogram for older people.

Aging Clin Exp Res 2018 Dec 17. Epub 2018 Dec 17.

University of Western Australia, Perth, WA, Australia.

Background: In older people, quantification of risk of reattendance after emergency department (ED) discharge is important to provide adequate post ED discharge care in the community to appropriately targeted patients at risk.

Methods: We reanalysed data from a prospective observational study, previously used for derivation of a nomogram for stratifying people aged 65 and older at risk for ED reattendance. We investigated the potential effect of comorbidity load and frailty by adding the Charlson or Elixhauser comorbidity index and a ten-item frailty measure from our data to develop four new nomograms. Read More

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http://dx.doi.org/10.1007/s40520-018-1089-4DOI Listing
December 2018
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Influence of bone densitometry on the anti-osteoporosis treatment after fragility hip fracture.

Aging Clin Exp Res 2018 Dec 17. Epub 2018 Dec 17.

The Department of Orthopaedics, The Second Affiliated Hospital of Fujian Medical University, Zhongshan North Road 34, Quanzhou, 362000, Fujian, China.

Background: Fragility fracture significantly increases risk of future fracture. The fragility fracture cycle should be disrupted. The secondary fracture prevention is important for the patients with fragility hip fracture. Read More

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http://dx.doi.org/10.1007/s40520-018-1094-7DOI Listing
December 2018
2 Reads

Assistive robots for socialization in elderly people: results pertaining to the needs of the users.

Aging Clin Exp Res 2018 Dec 17. Epub 2018 Dec 17.

Department of Medical Sciences, Geriatric Unit, Fondazione Casa Sollievo della Sofferenza, San Giovanni Rotondo, FG, Italy.

Background/aim: Technological solutions can support the elderly, improve their quality of life and reduce isolation and loneliness. The Euro-Japan ACCRA (Agile Co-Creation for Robots and Aging) project has the objective of building a reference co-creation methodology for the development of robotic solutions for ageing. The aim of this study is to provide a pilot qualitative analysis of the real needs of elderly people and their caregivers when exposed to conversational activities with robots and to identify priority needs that should be developed from end-user perspectives. Read More

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http://link.springer.com/10.1007/s40520-018-1073-z
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http://dx.doi.org/10.1007/s40520-018-1073-zDOI Listing
December 2018
10 Reads