2,603 results match your criteria Aging[Journal]


Molecular insights into vascular aging.

Aging (Albany NY) 2018 Dec 5. Epub 2018 Dec 5.

Division of Cardiovascular Medicine, University of Cambridge, Addenbrooke's Centre for Clinical Investigation, Addenbrooke's Hospital, Cambridge, UK.

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December 2018
1 Read

Aging, inhibition and GABA.

Aging (Albany NY) 2018 Dec 5. Epub 2018 Dec 5.

KU Leuven, Movement Control and Neuroplasticity Research Group, Department of Movement Sciences, Group Biomedical Sciences, Leuven 3001, Belgium.

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December 2018
1 Read

BCAR4 activates GLI2 signaling in prostate cancer to contribute to castration resistance.

Aging (Albany NY) 2018 Dec 4. Epub 2018 Dec 4.

Department of Urology, Shanghai Changzheng Hospital, Shanghai 200003, China.

Long non-coding RNAs (lncRNAs) have been found essential for tumorigenesis of prostate cancer (PC), but its role in the regulation of castration-resistant prostate cancer (CRPC) is poorly identified. Here, we showed that a lncRNA, Breast-Cancer Anti-Estrogen Resistance 4 (BCAR4), which plays a pivotal role in the tamoxifen-resistance of breast cancer, was significantly upregulated in CRPC, but not in castration-sensitive prostate cancer (CSPC), compared to normal prostate tissue. High BCAR4 levels in CRPC were correlated with poor patients' overall survival. Read More

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December 2018
1 Read

Reduced production of laminin by hepatic stellate cells contributes to impairment in oval cell response to liver injury in aged mice.

Aging (Albany NY) 2018 Dec 4. Epub 2018 Dec 4.

Department of General Surgery, The First Affiliated Hospital of Soochow University, Institutes for Translational Medicine, Soochow University, Suzhou, China.

Aged liver is usually impaired in response to hepatic injury. Tissue-specific stem cells participate in the repair of tissue injury. However, how oval cells (OCs) respond to injury and how the process is regulated by tissue microenvironment in aged mice have not been fully understood. Read More

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December 2018
4 Reads

Correction: CD40L promotes development of acute aortic dissection via induction of inflammation and impairment of endothelial cell function.

Aging (Albany NY) 2018 Nov;10(11):3627

Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.

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November 2018

Correction: MicroRNA-939 inhibits cell proliferation via targeting LRSAM1 in Hirschsprung's disease.

Aging (Albany NY) 2018 Nov;10(11):3626

State Key Laboratory of Reproductive Medicine, Institute of Toxicology, School of Public Health, Nanjing Medical University, Nanjing 211166, China.

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November 2018

LncRNA CDKN2BAS predicts poor prognosis in patients with hepatocellular carcinoma and promotes metastasis via the miR-153-5p/ARHGAP18 signaling axis.

Aging (Albany NY) 2018 Nov;10(11):3371-3381

Surgical Center, The Affiliated Wenling Hospital of Wenzhou Medical University, Wenling 317500, Zhejiang Province, China.

Background: Growing evidence shows that long noncoding RNAs (lncRNAs) play a crucial role in cancer progression. However, whether lncRNA CDKN2BAS is involved in human hepatocellular carcinoma (HCC) metastasis remains unclear.

Methods: Human lncRNA microarray analysis was performed to detect differential expression levels of lncRNAs in metastatic HCC tissues. Read More

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November 2018

Myoblasts rely on TAp63 to control basal mitochondria respiration.

Aging (Albany NY) 2018 Nov;10(11):3558-3573

Department of Experimental Medicine and TOR, University of Rome "Tor Vergata", Rome, Italy.

p53, with its family members p63 and p73, have been shown to promote myoblast differentiation by regulation of the function of the retinoblastoma protein and by direct activation of p21 and p57, promoting cell cycle exit. In previous studies, we have demonstrated that the TAp63γ isoform is the only member of the p53 family that accumulates during myoblasts differentiation, and that its silencing led to delay in myotube fusion. To better dissect the role of TAp63γ in myoblast physiology, we have generated both sh-p63 and Tet-On inducible TAp63γ clones. Read More

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November 2018
7 Reads

Erythrocytes and cardiovascular complications.

Aging (Albany NY) 2018 Nov 28. Epub 2018 Nov 28.

Division of Cardiology, Department of Medicine, Karolinska University Hospital, Karolinska Institutet, Stockholm 17176, Sweden.

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November 2018
3 Reads

Trends in stroke incidence among elderly low-income residents of rural China: a population-based study from 1992 to 2016.

Aging (Albany NY) 2018 Nov;10(11):3438-3449

Tianjin Neurological Institute, Key Laboratory of Post-Neuroinjury Neuro-repair and Regeneration in Central Nervous System, Ministry of Education and Tianjin City, Tianjin, 300052, China.

In China, >70% of stroke deaths occur in people aged ≥65 years. However, trends in the stroke incidence among elderly people are unclear. We aimed to determine trends in the stroke incidence among elderly people in rural China. Read More

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November 2018

methylation promotes oncogenesis of endometrial carcinoma through LOC134466/hsa-miR-196a-5p/TAC1 axis.

Aging (Albany NY) 2018 Nov;10(11):3353-3370

Department of Oncology, The First Clinic College of Hubei University of Chinese Medicine, Wuhan 430065, Hubei, China.

To investigate possible mechanism of abnormal methylation of long non-coding RNA (lncRNA) on endometrial carcinoma (EC) progression, we detected the genome methylation profiling of endometrial carcinoma by bioinformatic analysis. Accordingly, gene was chosen for the further research. We also found that was the target gene of and miRNA, hsa-miR-196a-5p, might form a connection between and . Read More

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November 2018

Positive association of familial longevity with the moderate-high HDL-C concentration in Bama Aging Study.

Aging (Albany NY) 2018 Nov;10(11):3528-3540

Department of Occupational and Environmental Health, School of Public Health, Guangxi Medical University, Nanning, China.

Familial longevity is characterized by beneficial metabolic phenotype in lipid metabolism and genetic variation. Although effects of lipid metabolism and the genetic basis for human longevity remain largely unclear, the contribution of high-density lipoprotein cholesterol (HDL-C) and ε2 allele has been repeatedly demonstrated. This study was designed to determine whether ApoE isoforms and HDL-C levels marked the familial longevity status in an offspring cohort with the age range of 20-89 years old and subsequently to explore the correlation between these two markers and the aging. Read More

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November 2018

Recycling the LDL receptor to combat atherosclerosis.

Aging (Albany NY) 2018 Nov 27. Epub 2018 Nov 27.

Department of Pediatrics, Molecular Genetics Section, University of Groningen, University Medical Center Groningen, Groningen 9713 AV, The Netherlands.

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November 2018

Suppression of mTORC1 activity in senescent Ras-transformed cells neither restores autophagy nor abrogates apoptotic death caused by inhibition of MEK/ERK kinases.

Aging (Albany NY) 2018 Nov;10(11):3574-3589

Institute of Cytology, Russian Academy of Sciences, St-Petersburg 194064, Russia.

Autophagy is conservative catabolic process that degrades organelles, in particular, mitochondria, and misfolded proteins within the lysosomes, thus maintaining cellular viability. Despite the close relationship between mitochondrial dysfunction and cellular senescence, it is unclear how mitochondria damage can induce autophagy in senescent cells. We show that MEK/ERK suppression induces mitochondria damage followed by apoptosis of senescent Ras-expressing cells. Read More

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November 2018

TGF-β induces corneal endothelial senescence via increase of mitochondrial reactive oxygen species in chronic corneal allograft failure.

Aging (Albany NY) 2018 Nov;10(11):3474-3485

Key Laboratory, Department of Otolaryngology-Head and Neck Surgery, Affiliated Hospital of Qingdao University, Qingdao, China.

The corneal endothelium (CE) dysfunction impairs optical transparency and leads to corneal allograft failure. Morphologically, CE cells are characterized by premature senescence at the late stage of corneal graft. However, the detailed molecular mechanisms are largely unknown. Read More

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November 2018
2 Reads

Cell and tissue type independent age-associated DNA methylation changes are not rare but common.

Aging (Albany NY) 2018 Nov;10(11):3541-3557

CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, Shanghai Institute for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai 200031, China.

Age-associated DNA methylation changes have been widely reported across many different tissue and cell types. Epigenetic 'clocks' that can predict chronological age with a surprisingly high degree of accuracy appear to do so independently of tissue and cell-type, suggesting that a component of epigenetic drift is cell-type independent. However, the relative amount of age-associated DNAm changes that are specific to a cell or tissue type versus the amount that occurs independently of cell or tissue type is unclear and a matter of debate, with a recent study concluding that most epigenetic drift is tissue-specific. Read More

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November 2018

Transcriptional expressions of Chromobox 1/2/3/6/8 as independent indicators for survivals in hepatocellular carcinoma patients.

Aging (Albany NY) 2018 Nov;10(11):3450-3473

Department of Infectious Diseases, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.

Chromobox (CBX) proteins are important components of epigenetic regulation complexes known to play key roles in hepatocellular carcinoma (HCC). Little is known about the function of distinct CBXs in HCC. To address this issue, the study investigated the roles of CBXs in the prognosis of HCC using ONCOMINE, UALCAN, Human Protein Atlas, Kaplan-Meier Plotter, databases. Read More

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November 2018
2 Reads

Angiopoietin-1 and ανβ3 integrin peptide promote the therapeutic effects of L-serine in an amyotrophic lateral sclerosis/Parkinsonism dementia complex model.

Aging (Albany NY) 2018 Nov;10(11):3507-3527

Institute of Anatomy and Cell Biology, Medical College, Zhejiang University, Hangzhou, China.

Amyotrophic lateral sclerosis (ALS) is an adult disorder of neurodegeneration that manifests as the destruction of upper and lower motor neurons. Beta-N-methylamino-L-alanine (L-BMAA), an amino acid not present in proteins, was found to cause intraneuronal protein misfolding and to induce ALS/Parkinsonism dementia complex (PDC), which presents symptoms analogous to those of Alzheimer's-like dementia and Parkinsonism. L-serine suppresses the erroneous incorporation of L-BMAA into proteins in the human nervous system. Read More

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November 2018
1 Read

Gender, GABAergic dysfunction and AD.

Aging (Albany NY) 2018 Nov 26. Epub 2018 Nov 26.

Paul Flechsig Institute for Brain Research, University of Leipzig, Leipzig D-04103, Germany.

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November 2018
9 Reads

Role of echocardiography in CRT.

Aging (Albany NY) 2018 Nov 26. Epub 2018 Nov 26.

Aalborg University Hospital, Department of Cardiology, Aalborg, Denmark.

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November 2018
2 Reads

miR-150-5p suppresses tumor progression by targeting VEGFA in colorectal cancer.

Aging (Albany NY) 2018 Nov;10(11):3421-3437

General Clinical Research Center, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, Jiangsu, China.

MicroRNA-150-5p (miR-150-5p) has been implicated in tumor initiation and progression in a variety of cancers. However, its roles in colorectal cancer (CRC) remain largely unknown. In our study, a decreased miR-150-5p expression in CRC tissues was found to be associated with poor overall survival. Read More

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November 2018

Phosphatidylcholine could protect the defect of zearalenone exposure on follicular development and oocyte maturation.

Aging (Albany NY) 2018 Nov;10(11):3486-3506

College of Life Sciences, Institute of Reproductive Sciences, Qingdao Agricultural University, Qingdao 266109, China.

Zearalenone (ZEA) is a well-known exogenous endocrine disruptor and can lead to severe negative effects on the human and animal reproductive process. Using a follicle culture model, we have previously shown that ZEA exposure significantly affected the follicular development and antrum formation but the underlying mechanisms are not well known. Therefore, in this study, we explored the metabolomic changes of granulosa cell (GC) culture media with or without ZEA exposure. Read More

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November 2018

Cell cycle-dependent and -independent telomere shortening accompanies murine brain aging.

Aging (Albany NY) 2018 Nov;10(11):3397-3420

Hans Berger Department of Neurology, Jena University Hospital, Jena, Thuringia 07747, Germany.

Replication-based telomere shortening during lifetime is species- and tissue-specific, however, its impact on healthy aging is unclear. In particular, the contribution of telomere truncation to the aging process of the CNS, where replicative senescence alone fails to explain organ aging due to low to absent mitotic activity of intrinsic populations, is undefined. Here, we assessed changes in relative telomere length in non-replicative and replicative neural brain populations and telomerase activity as a function of aging in C57BL/6 mice. Read More

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November 2018
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Greater loss of mitochondrial function with ageing is associated with earlier onset of sarcopenia in .

Aging (Albany NY) 2018 Nov;10(11):3382-3396

MRC/ARUK Centre for Musculoskeletal Ageing Research, NIHR Nottingham BRC, University of Nottingham, Nottingham, UK.

Sarcopenia, the age-related decline of muscle, is a significant and growing public health burden. , a model organism for investigating the mechanisms of ageing, also displays sarcopenia, but the underlying mechanism(s) remain elusive. Here, we use natural scaling of lifespan in response to temperature to examine the relationship between mitochondrial content, mitochondrial function, and sarcopenia. Read More

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November 2018
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Oxidative muscles have better mitochondrial homeostasis than glycolytic muscles throughout life and maintain mitochondrial function during aging.

Aging (Albany NY) 2018 Nov;10(11):3327-3352

Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.

Preservation of mitochondrial function, which is dependent on mitochondrial homeostasis (biogenesis, dynamics, disposal/recycling), is critical for maintenance of skeletal muscle function. Skeletal muscle performance declines upon aging (sarcopenia) and is accompanied by decreased mitochondrial function in fast-glycolytic muscles. Oxidative metabolism promotes mitochondrial homeostasis, so we investigated whether mitochondrial function is preserved in oxidative muscles. Read More

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November 2018
2 Reads

Disease or not, aging is easily treatable.

Aging (Albany NY) 2018 Nov;10(11):3067-3078

Cell Stress Biology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.

Is aging a disease? It does not matter because aging is already treated using a combination of several clinically-available drugs, including rapamycin. Whether aging is a disease depends on arbitrary definitions of both disease and aging. For treatment purposes, aging is a deadly disease (or more generally, pre-disease), despite being a normal continuation of normal organismal growth. Read More

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November 2018

ZNF185 is a p53 target gene following DNA damage.

Aging (Albany NY) 2018 Nov;10(11):3308-3326

Department of Experimental Medicine, TOR, University of Rome "Tor Vergata", Rome 00133, Italy.

The transcription factor p53 is a key player in the tumour suppressive DNA damage response and a growing number of target genes involved in these pathways has been identified. p53 has been shown to be implicated in controlling cell motility and its mutant form enhances metastasis by loss of cell directionality, but the p53 role in this context has not yet being investigated. Here, we report that ZNF185, an actin cytoskeleton-associated protein from LIM-family of Zn-finger proteins, is induced following DNA-damage. Read More

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November 2018
5 Reads

Effects of senescent secretory phenotype acquisition on human retinal pigment epithelial stem cells.

Aging (Albany NY) 2018 Nov;10(11):3173-3184

Department of Clinical and Molecular Sciences-Histology, Università Politecnica delle Marche, Ancona 60020, Italy.

Regenerative medicine approaches based on mesenchymal stem cells (MSCs) are being investigated to treat several aging-associated diseases, including age-related macular degeneration (AMD). Loss of retinal pigment epithelium (RPE) cells occurs early in AMD, and their transplant has the potential to slow disease progression.The human RPE contains a subpopulation of cells - adult RPE stem cells (RPESCs) - that are capable of self-renewal and of differentiating into RPE cells . Read More

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November 2018

Glucose negatively affects Nrf2/SKN-1-mediated innate immunity in .

Aging (Albany NY) 2018 Nov;10(11):3089-3103

Key Laboratory of Nanobiological Technology of Chinese Ministry of Health, Xiangya Hospital, Central South University, Changsha 410008, China.

High glucose levels negatively affect immune response. However, the underlying mechanisms are not well understood. Upon infection, the round worm induces multiple gene transcription programs, including the Nrf2/SKN-1-mediated detoxification program, to activate the innate immunity. Read More

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November 2018

Vascular inflammation in aging.

Aging (Albany NY) 2018 Nov 15. Epub 2018 Nov 15.

Cardiovascular Biology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.

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November 2018

Azithromycin and Roxithromycin define a new family of "senolytic" drugs that target senescent human fibroblasts.

Aging (Albany NY) 2018 Nov;10(11):3294-3307

Translational Medicine, University of Salford, Greater Manchester, United Kingdom.

Here, we employed a "senolytic" assay system as a screening tool, with the goal of identifying and repurposing FDA-approved antibiotics, for the targeting of the senescent cell population. Briefly, we used two established human fibroblast cell lines (MRC-5 and/or BJ) as model systems to induce senescence, via chronic treatment with a DNA-damaging agent, namely BrdU (at a concentration of 100 μM for 8 days). Cell viability was then monitored by using the SRB assay, to measure protein content. Read More

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November 2018
1 Read

The heterogeneity within Alzheimer's disease.

Aging (Albany NY) 2018 Nov;10(11):3058-3060

Division of Clinical Geriatrics, Centre for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.

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November 2018
4 Reads

Autophagy in neurodegeneration and aging.

Aging (Albany NY) 2018 Nov 14. Epub 2018 Nov 14.

Hirosaki University Graduate School of Medicine, Department of Neuropathology, Institute of Brain Science, Hirosaki, Japan.

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November 2018
1 Read

Methanolic extract of attenuates hyperhomocysteinemia induced AD-like pathology and cognitive impairments in rats.

Aging (Albany NY) 2018 Nov;10(11):3229-3248

Department of Pathophysiology, School of Basic Medicine, Key Laboratory of Education Ministry of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.

Although few drugs are available today for the management of Alzheimer's disease (AD) and many plants and their extracts are extensively employed in animals' studies and AD patients, yet no drug or plant extract is able to reverse AD symptoms adequately. In the present study, (TG), a naturally occurring plant known for its strong antioxidative, anti-inflammatory and anti-amyloidogenic properties, was evaluated on homocysteine (Hcy) induced AD-like pathology and cognitive impairments in rats. We found that TG attenuated Hcy-induced oxidative stress and memory deficits. Read More

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November 2018
3 Reads

Aging and drug discovery.

Aging (Albany NY) 2018 Nov;10(11):3079-3088

Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.

Multiple interventions in the aging process have been discovered to extend the healthspan of model organisms. Both industry and academia are therefore exploring possible transformative molecules that target aging and age-associated diseases. In this overview, we summarize the presented talks and discussion points of the 5th Annual Aging and Drug Discovery Forum 2018 in Basel, Switzerland. Read More

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November 2018
3 Reads
6.430 Impact Factor

APP signaling in Alzheimer's disease.

Aging (Albany NY) 2018 Nov;10(11):3063-3064

Instituto de Investigación Médica "Mercedes y Martín Ferreyra", INIMEC-CONICET- Universidad Nacional de Córdoba, Córdoba, Argentina.

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November 2018

Uncoupling protein 4 () gene variability in neurodegenerative disorders: further evidence of association in Frontotemporal dementia.

Aging (Albany NY) 2018 Nov;10(11):3283-3293

Department of Biology, Ecology and Earth Sciences, University of Calabria, Rende, Italy.

Ongoing research suggests that mitochondrial dysfunction is a common hallmark in neurodegenerative diseases, pointing to mitochondrial uncoupling process as a critical player. We recently reported that rs9472817-C/G, an intronic variant of neuronal mitochondrial uncoupling protein-4 () gene affects the risk of late onset Alzheimer's disease (LOAD), and that the variant's effect is strongly dependent on -ε4 status. Here, we extended our analysis to a cohort of 751 subjects including late-onset familial and sporadic cases of frontotemporal dementia (FTD; 213), Parkinson disease (PD;96), and 442 healthy controls. Read More

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November 2018
1 Read

Aging clocks: disrupted circadian rhythms.

Aging (Albany NY) 2018 Nov;10(11):3065-3066

Medway School of Pharmacy, University of Kent, Chatham, UK.

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November 2018

THC for age-related cognitive decline?

Authors:
Yosef Sarne

Aging (Albany NY) 2018 Nov 12. Epub 2018 Nov 12.

Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

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November 2018
5 Reads

How age affects reinforcement learning.

Aging (Albany NY) 2018 Nov 12. Epub 2018 Nov 12.

Center for Molecular and Behavioral Neuroscience, Rutgers University, Newark, Newark, NJ 07102, USA.

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November 2018

Accelerated aging in perinatally HIV-infected children: clinical manifestations and pathogenetic mechanisms.

Aging (Albany NY) 2018 Nov;10(11):3610-3625

Section of Oncology and Immunology, Department of Surgery, Oncology and Gastroenterology, Unit of viral Oncology and AIDS Reference Center, University of Padova, Padova, Italy.

Background: Premature aging and related diseases have been documented in HIV-infected adults. Data are now emerging also regarding accelerated aging process in HIV-infected children.

Methods: A narrative review was performed searching studies on PubMed published in English language in 2004-2017, using appropriate key words, including "aging", "children", "HIV", "AIDS", "immunosenescence", "pathogenesis", "clinical conditions". Read More

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November 2018
3 Reads

PhotoAgeClock: deep learning algorithms for development of non-invasive visual biomarkers of aging.

Aging (Albany NY) 2018 Nov;10(11):3249-3259

Beiersdorf AG, Hamburg, Germany.

Aging biomarkers are the qualitative and quantitative indicators of the aging processes of the human body. Estimation of biological age is important for assessing the physiological state of an organism. The advent of machine learning lead to the development of the many age predictors commonly referred to as the "aging clocks" varying in biological relevance, ease of use, cost, actionability, interpretability, and applications. Read More

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November 2018
37 Reads

Inflammatory markers and mediators in heart disease.

Aging (Albany NY) 2018 Nov;10(11):3061-3062

Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.

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November 2018

Accelerated DNA methylation age and the use of antihypertensive medication among older adults.

Aging (Albany NY) 2018 Nov;10(11):3210-3228

Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA.

The discrepancy of DNA methylation age (DNAmAge) with chronological age (termed as age acceleration, AA) has been identified to be associated with many aging-related health outcomes including hypertension. Since taking antihypertensive medication (AHM) could prevent aging-related diseases caused by hypertension, we hypothesized that using AHM could also reduce the AA. We examined this hypothesis among 546 males aged 55-85 years by exploring the associations of AHM use with AA and its change rate (Δ) in two visits with a median follow-up of 3. Read More

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November 2018
3 Reads

Spindle pole body component 25 regulates stemness of prostate cancer cells.

Aging (Albany NY) 2018 Nov;10(11):3273-3282

Department of Urology, Zhenjiang First People's Hospital, Zhenjiang 212002, China.

Spindle pole body component 25 (SPC25) is a component of NDC80 complex that controls spindle assembly checkpoint in the microtubule-binding domain of kinetochores. We recently showed that SPC25 is required for prostate cancer (PrC) cell proliferation and cell cycle progression, and here we investigated whether SPC25 may be a Cancer stem cell (CSC) marker in PrC. We found that the levels of SPC25 were higher in PrC samples than paired normal prostate tissue. Read More

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November 2018
8 Reads

Overexpression of and genes affects lifespan, stress resistance and locomotor activity in .

Aging (Albany NY) 2018 Nov;10(11):3260-3272

Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow 119991, Russia.

Recent experimental studies highlighted the role of hydrogen sulfide (HS) in aging and longevity. The cystathionine ß-synthase (CBS) and cystathionine γ-lyase (CSE) are the key enzymes responsible for HS production. Here we investigated the geroprotective effects of and overexpression in . Read More

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November 2018
4 Reads

Identification of an energy metabolism-related signature associated with clinical prognosis in diffuse glioma.

Aging (Albany NY) 2018 Nov;10(11):3185-3209

Department of Molecular Neuropathology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, 100050, China.

Now, numerous exciting findings have been yielded in the field of energy metabolism within glioma cells. In addition to aerobic glycolysis, multiple catabolic pathways are employed for energy production. However, the prognostic significance of energy metabolism in glioma remains obscure. Read More

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November 2018
3 Reads

Blood pressure lowering in acute intracerebral hemorrhage.

Aging (Albany NY) 2018 Nov;10(11):3056-3057

Stroke Unit, Department of Neurology, Vall d'Hebron University Hospital, Barcelona, Spain.

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November 2018

Do platelets LINE up for aging?

Aging (Albany NY) 2018 Nov;10(11):3054-3055

University of Utah Molecular Medicine Program, University of Utah, Salt Lake City, UT 84108, USA.

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November 2018

Filamin A modulates platelet function.

Aging (Albany NY) 2018 Nov;10(11):3052-3053

Department of Physiology, Cellular Physiology Research Group, Institute of Molecular Pathology Biomarkers, University of Extremadura, Caceres 10003, Spain.

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November 2018