5,246 results match your criteria Age and ageing[Journal]


Frailty predicts mortality in all emergency surgical admissions regardless of age. An observational study.

Age Ageing 2019 Feb 19. Epub 2019 Feb 19.

Ageing Clinical & Experimental Research (ACER) Team, Institute of Applied Health Research, University of Aberdeen, Aberdeen, UK.

Background: frail patients in any age group are more likely to die than those that are not frail. We aimed to evaluate the impact of frailty on clinical mortality, readmission rate and length of stay for emergency surgical patients of all ages.

Methods: a multi-centre prospective cohort study was conducted on adult admissions to acute surgical units. Read More

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http://dx.doi.org/10.1093/ageing/afy217DOI Listing
February 2019

Changes in physical and mental health are associated with cardiovascular disease incidence in postmenopausal women.

Age Ageing 2019 Feb 11. Epub 2019 Feb 11.

Department of Medicine, School of Medicine, Stanford University, Stanford, USA.

Background: physical and mental health are important risk factors for cardiovascular disease (CVD) incidence and death among postmenopausal women. The objective of this study was to assess whether changes in physical and mental health were associated with CVD incidence and death.

Methods: in the Women's Health Initiative Observational Study, 48,906 women (50-79 years) had complete data at baseline on physical and mental health (assessed with Short Form-36) and key covariates. Read More

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http://dx.doi.org/10.1093/ageing/afy213DOI Listing
February 2019
3.642 Impact Factor

Unilateral hearing loss in a 94-year-old patient.

Age Ageing 2019 Feb 6. Epub 2019 Feb 6.

Department of Geratology, John Radcliffe Hospital Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

A case report of a 94-year-old, previously well male patient who presented with fever thought to be caused by community acquired pneumonia, new unilateral hearing loss and reduced consciousness. Despite antibiotic treatment he continued to deteriorate. Brain imaging with computer tomography and magnetic resonance imaging revealed a left otomastoiditis with osteomyelitis of the skull base, associated with an adjacent subdural empyema. Read More

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http://dx.doi.org/10.1093/ageing/afz003DOI Listing
February 2019
2 Reads

Obesity and Longer Term Risks of Dementia in 65-74 Year Olds.

Age Ageing 2019 Feb 6. Epub 2019 Feb 6.

Epidemiology and Public Health, Institute of Biomedical and Clinical Science, University of Exeter Medical School, Barrack Road, Exeter EX2 5DW, UK.

Background: overweight or obesity at ages <65 years associates with increased dementia incidence, but at ≥65 years estimates are paradoxical. Weight loss before dementia diagnosis, plus smoking and diseases causing weight loss may confound associations.

Objective: to estimate weight loss before dementia diagnosis, plus short and longer-term body mass index associations with incident dementia in 65-74 year olds within primary care populations in England. Read More

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http://dx.doi.org/10.1093/ageing/afz002DOI Listing
February 2019
1 Read

Quality improvement strategies to prevent falls in older adults: a systematic review and network meta-analysis.

Age Ageing 2019 Feb 5. Epub 2019 Feb 5.

Knowledge Translation Program, Li Ka Shing Knowledge Institute, St. Michael's Hospital, 209 Victoria Street, East Building, Toronto, ON Canada.

Background: Falls are a common occurrence and the most effective quality improvement (QI) strategies remain unclear.

Methods: We conducted a systematic review and network meta-analysis (NMA) to elucidate effective quality improvement (QI) strategies for falls prevention. Multiple databases were searched (inception-April 2017). Read More

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http://dx.doi.org/10.1093/ageing/afy219DOI Listing
February 2019
2 Reads

Older men may benefit from antimicrobial prophylaxis for recurrent urinary tract infections.

Age Ageing 2019 Feb 4. Epub 2019 Feb 4.

Department of Internal Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, CT, USA.

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http://dx.doi.org/10.1093/ageing/afy195DOI Listing
February 2019

Physical frailty in older men: prospective associations with diet quality and patterns.

Age Ageing 2019 Jan 22. Epub 2019 Jan 22.

UCL Department of Primary Care & Population Health, UCL Medical School, Rowland Hill Street, London, UK.

Background: increasing numbers of older adults are living with frailty and its adverse consequences. We investigated relationships between diet quality or patterns and incident physical frailty in older British men and whether any associations were influenced by inflammation.

Methods: prospective study of 945 men from the British Regional Heart Study aged 70-92 years with no prevalent frailty. Read More

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http://dx.doi.org/10.1093/ageing/afy216DOI Listing
January 2019
3 Reads

Growing research in geriatric medicine.

Age Ageing 2019 Jan 22. Epub 2019 Jan 22.

AGE Research Group, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK.

Academic geriatric medicine activity lags behind the scale of clinical activity in the specialty. A meeting of UK academic geriatricians was convened in March 2018 to consider causes and solutions to this problem. The meeting highlighted a lack of research-active clinicians, a perception that research is not central to the practice of geriatric medicine and a failure to translate discovery science to clinical studies. Read More

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http://dx.doi.org/10.1093/ageing/afy220DOI Listing
January 2019

Frailty and comorbidity predict first hospitalisation after heart failure diagnosis in primary care: population-based observational study in England.

Age Ageing 2019 Jan 9. Epub 2019 Jan 9.

National Heart & Lung Institute, Royal Brompton Hospital, Imperial College London, Sydney St, Chelsea, London, UK.

Background: frailty has only recently been recognised as important in patients with heart failure (HF), but little has been done to predict the first hospitalisation after diagnosis in unselected primary care populations.

Objectives: to predict the first unplanned HF or all-cause admission after diagnosis, comparing the effects of comorbidity and frailty, the latter measured by the recently validated electronic frailty index (eFI).

Design: observational study. Read More

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http://dx.doi.org/10.1093/ageing/afy194DOI Listing
January 2019
2 Reads

Where are we now in perioperative medicine? Results from a repeated UK survey of geriatric medicine delivered services for older people.

Age Ageing 2019 Jan 9. Epub 2019 Jan 9.

Department of Ageing and Health, Guy's and St Thomas' NHS Foundation Trust, London, UK.

Introduction: national reports highlight deficiencies in the care of older patients undergoing surgery. A 2013 survey showed less than a third of NHS trusts had geriatrician-led perioperative medicine services for older surgical patients. Barriers to establishing services included funding, workforce and limited interspecialty collaboration. Read More

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http://dx.doi.org/10.1093/ageing/afy218DOI Listing
January 2019
1 Read

Adiposity in middle and old age and risk of death from dementia: 40-year follow-up of 19,000 men in the Whitehall study.

Age Ageing 2019 Jan 9. Epub 2019 Jan 9.

Faculty of Epidemiology and Population Health, Department of Community Medicine, London School of Hygiene and Tropical Medicine and Adjunct Professor of Epidemiology, UiT the Arctic University of Norway, Tromsø, Norway.

Aims And Objectives: to examine the hypothesis that obesity is protective for dementia, we compared the associations of death from dementia with body weight and body mass index (BMI) in both middle and old age.

Design: height and weight were measured in a prospective study of 19,019 middle-aged men in the Whitehall study in 1967-70 and in 6,158 surviving participants at resurvey in 1997. Cox regression was used to examine the associations of death from dementia over a 40-year period with weight or BMI measured by health professionals in middle and old age adjusting for age, smoking habits, employment grade and marital status. Read More

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http://dx.doi.org/10.1093/ageing/afy182DOI Listing
January 2019
3 Reads

Experiences with and outcomes of Advance Care Planning in bereaved relatives of frail older patients: a mixed methods study.

Age Ageing 2019 Jan 7. Epub 2019 Jan 7.

Department of Public Health, Erasmus MC, University Medical Center Rotterdam, CA Rotterdam, The Netherlands.

Background: Advance Care Planning (ACP) may prepare relatives of frail older patients for future decision-making.

Objective: to investigate (1) how bereaved relatives of frail older patients experience ACP conversations and (2) whether ACP has an effect on relatives' preparation for decision-making and on their levels of anxiety and depression.

Design: cluster randomised controlled trial. Read More

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http://dx.doi.org/10.1093/ageing/afy184DOI Listing
January 2019
1 Read

Subjective memory complaints and incident dementia in a high risk older adult hypertensive population.

Age Ageing 2019 Jan 7. Epub 2019 Jan 7.

Neuroscience Research Australia, Sydney, Australia.

Background: there is a growing body of evidence demonstrating an association between subjective memory complaints (SMC) and an increased risk of incident cognitive decline or dementia. To date this has not been examined in hypertensive older adults, a prevalent and growing population group at high risk of cognitive decline.

Methods: using data from participants in the Hypertension in the Very Elderly Trial cohort the association between baseline SMC and incident cognitive decline and dementia was examined using Cox proportional hazard regression. Read More

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http://dx.doi.org/10.1093/ageing/afy193DOI Listing
January 2019
2 Reads

Regaining pre-fracture basic mobility status after hip fracture and association with post-discharge mortality and readmission-a nationwide register study in Denmark.

Age Ageing 2019 Jan 7. Epub 2019 Jan 7.

Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark.

Background: early mobilization after hip fracture (HF) is an important predictor of outcome, but knowledge of the consequences of not achieving the pre-fracture basic mobility status in acute hospital recovery is sparse.

Objective: we examined whether the regain of pre-fracture basic mobility status evaluated with the cumulated ambulation score (CAS) at hospital discharge was associated with 30-day post-discharge mortality and readmission.

Design: this is a population-based cohort study. Read More

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https://academic.oup.com/ageing/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/ageing/afy185DOI Listing
January 2019
10 Reads

Person-centred prophylaxis for venous thromboembolism.

Authors:
Ian P Donald

Age Ageing 2019 Jan 7. Epub 2019 Jan 7.

Department of Old Age Medicine, Gloucestershire Royal Hospital, Great Western Road, Gloucester, UK.

All medical admissions should receive risk assessment for the value of prophylaxis against venous thromboembolism. Unfortunately, for such patients the risk of thromboembolism is closely balanced with the risk of haemorrhage exaggerated by chemical prophylaxis. The recent NICE guideline continues to recommend comprehensive risk assessment, and to use prophylaxis where the risk of thromboembolism exceeds the risk of bleeding. Read More

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http://dx.doi.org/10.1093/ageing/afy190DOI Listing
January 2019
1 Read

Measuring health-related quality of life of care home residents: comparison of self-report with staff proxy responses.

Age Ageing 2019 Jan 7. Epub 2019 Jan 7.

Division of Medical Sciences and Graduate Entry Medicine, School of Medicine, University of Nottingham, Derby, UK.

Introduction: care home residents are often unable to complete health-related quality of life questionnaires for themselves because of prevalent cognitive impairment. This study compared care home resident and staff proxy responses for two measures, the EQ-5D-5L and HowRU.

Methods: a prospective cohort study recruited residents ≥60 years across 24 care homes who were not receiving short stay, respite or terminal care. Read More

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http://dx.doi.org/10.1093/ageing/afy191DOI Listing
January 2019
3 Reads
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Effects of a falls prevention exercise programme on health-related quality of life in older home care recipients: a randomised controlled trial.

Age Ageing 2019 Jan 7. Epub 2019 Jan 7.

Department of Physiotherapy, OsloMet-Oslo Metropolitan University, PO Box 4 St. Olavs Plass, Oslo, Norway.

Background: falls have serious consequences for quality of life (QOL) and contribute substantially to the global burden of disease. Home care is an important arena to address falls prevention and QOL, but this vulnerable group of older adults is underrepresented in health research. This study explores the effects of a falls prevention exercise programme on health-related quality of life (HRQOL), physical function and falls self-efficacy in older fallers receiving home care. Read More

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http://dx.doi.org/10.1093/ageing/afy192DOI Listing
January 2019
1 Read

Podiatry interventions to prevent falls in older people: a systematic review and meta-analysis.

Age Ageing 2019 Jan 7. Epub 2019 Jan 7.

School of Nursing and Health Sciences, University of Dundee, 11 Airlie Place, Dundee, UK.

Background: foot problems are independent risk factors for falls in older people. Podiatrists diagnose and treat a wide range of problems affecting the feet, ankles and lower limbs. However, the effectiveness of podiatry interventions to prevent falls in older people is unknown. Read More

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https://academic.oup.com/ageing/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/ageing/afy189DOI Listing
January 2019
2 Reads
3.642 Impact Factor

Relationship between HbA1c and all-cause mortality in older patients with insulin-treated type 2 diabetes: results of a large UK Cohort Study.

Age Ageing 2019 Jan 7. Epub 2019 Jan 7.

Division of Medical Sciences and Graduate Entry Medicine, School of Medicine, University of Nottingham, Royal Derby Hospital Centre, Derby.

Background: our aim was to study the relationship between HbA1c and cardiovascular morbidity and all-cause mortality among older insulin-treated patients with type 2 diabetes (T2D) after adjustment for multiple confounders.

Methods: data for 4589 adults with T2D (>65 years) on insulin treatment were sourced from 532 UK General Practices via the Health Improvement Network (THIN) database. Cox proportional hazard models and Kaplan-Meier estimators were fitted to derive the hazards of all-cause mortality by HbA1c categories (<6. Read More

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http://dx.doi.org/10.1093/ageing/afy178DOI Listing
January 2019
1 Read

Lifetime physical activity and late-life cognitive function: the Rancho Bernardo study.

Age Ageing 2019 Jan 7. Epub 2019 Jan 7.

Department of Family Medicine and Public Health, University of California, San Diego, USA.

Background: physical activity in older age has been associated with better cognitive function, but the role of earlier life physical activity is less well understood.

Objective: determine associations between physical activity throughout the lifespan and cognitive function in older age.

Design: cross-sectional study. Read More

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https://academic.oup.com/ageing/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/ageing/afy188DOI Listing
January 2019
2 Reads

Clinical research methods for studies of older people.

Age Ageing 2019 Jan 4. Epub 2019 Jan 4.

NIHR Newcastle Biomedical Research Centre, Newcastle University and Newcastle upon Tyne Hospitals, Campus for Ageing and Vitality, Newcastle, UK.

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http://dx.doi.org/10.1093/ageing/afy215DOI Listing
January 2019
1 Read

Assessing and managing concurrent hearing, vision and cognitive impairments in older people: an international perspective from healthcare professionals.

Age Ageing 2019 Jan 4. Epub 2019 Jan 4.

Department of Health Sciences, School of Sciences, European University Cyprus, 6 Diogenes Str, Nicosia, Cyprus.

Background: there is a significant gap in the understanding, assessment and management of people with dementia and concurrent hearing and vision impairments.

Objective: from the perspective of professionals in dementia, hearing and vision care, we aimed to: (1) explore the perceptions of gaps in assessment and service provision in ageing-related hearing, vision and cognitive impairment; (2) consider potential solutions regarding this overlap and (3) ascertain the attitudes, awareness and practice, with a view to implementing change.

Methods: our two-part investigation with hearing, vision, and dementia care professionals involved: (1) an in-depth, interdisciplinary, international Expert Reference Group (ERG; n = 17) and (2) a wide-scale knowledge, attitudes and practice survey (n = 653). Read More

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http://dx.doi.org/10.1093/ageing/afy183DOI Listing
January 2019
2 Reads

Impact of sarcopenia on 1-year mortality in older patients with cancer.

Age Ageing 2019 Jan 4. Epub 2019 Jan 4.

Charité-Universitätsmedizin Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Department of Geriatrics, Research Group Geriatrics, Berlin, Germany.

Objectives: sarcopenia is common especially in hospitalised older populations. The aim of this study was to assess the prevalence of sarcopenia, defined as low skeletal mass and muscle strength, and its impact on 1-year mortality in older patients with cancer.

Methods: skeletal muscle mass was estimated using bioelectric impedance analysis and related to height2 (SMI; Janssen et al. Read More

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https://academic.oup.com/ageing/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/ageing/afy212DOI Listing
January 2019
18 Reads

The electronic frailty index as an indicator of community healthcare service utilisation in the older population.

Age Ageing 2018 Dec 27. Epub 2018 Dec 27.

Faculty of Medicine and Health Sciences, Department of Clinical Psychology, Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich, UK.

Background: older people with frailty are particularly high users of healthcare services, however a lack of standardised recording of frailty in different healthcare electronic datasets has limited investigations into healthcare service usage and demand of the older frail population.

Objectives: to investigate the community service demand of frail patients using the electronic frailty index (eFI) as a measure of frailty.

Study Design And Setting: a retrospective cohort study using anonymised linked healthcare patient data from primary care, community services and acute hospitals in Norfolk. Read More

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http://dx.doi.org/10.1093/ageing/afy181DOI Listing
December 2018
1 Read

The prevalence of non-communicable disease in older people in prison: a systematic review and meta-analysis.

Age Ageing 2018 Dec 27. Epub 2018 Dec 27.

Nuffield Department of Clinical Medicine, Centre for Tropical Medicine and Global Health, University of Oxford, UK.

Background: people in prison often experience poor health. Those aged 50 and over are the fastest growing age-group in prison and present particular challenges to criminal justice systems around the world. Non-communicable diseases (NCDs) account for two-thirds of deaths globally and no estimate of the prevalence of NCDs in this vulnerable population exists. Read More

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https://academic.oup.com/ageing/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/ageing/afy186DOI Listing
December 2018
7 Reads

Effects of exercise and nutrition supplementation in community-dwelling older Chinese people with sarcopenia: a randomized controlled trial.

Age Ageing 2018 Nov 14. Epub 2018 Nov 14.

Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong.

Background: Limited trials examining the effect of exercise and nutrition supplementation in older people with sarcopenia are available.

Objectives: to assess the impact of resistance exercise program targeting muscle strength and power with and without nutrition supplementation on gait speed, body composition, physical function and quality of life.

Methods: this trial randomized 113 community-dwelling older Chinese adults aged ≥65 and with sarcopenia defined using the Asian Criteria into one of the three groups: exercise program alone, combined-exercise program and nutrition supplement or waitlist control. Read More

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http://dx.doi.org/10.1093/ageing/afy179DOI Listing
November 2018
12 Reads

Management of atrial fibrillation for older people with frailty: a systematic review and meta-analysis.

Age Ageing 2018 Nov 15. Epub 2018 Nov 15.

Department of Clinical and Population Sciences, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Worsley Building, Level 11, Clarendon Way, Leeds, UK.

Background: despite a large and growing population of older people with frailty and atrial fibrillation (AF), there is a lack of guidance on optimal AF management in this high-risk group.

Objective: to synthesise the existing evidence base on the association between frailty, AF and clinical outcomes.

Methods: a systematic review of studies examining the association between validated measures of frailty, AF and clinical outcomes, and meta-analysis of the association between frailty and oral anticoagulation (OAC) prescription. Read More

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http://dx.doi.org/10.1093/ageing/afy180DOI Listing
November 2018
1 Read

European postgraduate curriculum in geriatric medicine developed using an international modified Delphi technique.

Age Ageing 2018 Nov 13. Epub 2018 Nov 13.

Institute of Biomedicine of Ageing, Friedrich Alexander University Erlangen, Schloßplatz 4, Erlangen, Germany.

Background: the European Union of Medical Specialists (UEMS-GMS) recommendations for training in Geriatric Medicine were published in 1993. The practice of Geriatric Medicine has developed considerably since then and it has therefore become necessary to update these recommendations.

Methods: under the auspices of the UEMS-GMS, the European Geriatric Medicine Society (EuGMS) and the European Academy of Medicine of Ageing (EAMA), a group of experts, representing all member states of the respective bodies developed a new framework for education and training of specialists in Geriatric Medicine using a modified Delphi technique. Read More

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https://academic.oup.com/ageing/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/ageing/afy173DOI Listing
November 2018
18 Reads
3.642 Impact Factor

The impact of comorbidity on the quality of life of people with dementia: findings from the IDEAL study.

Age Ageing 2018 Nov 7. Epub 2018 Nov 7.

REACH: The Centre for Research in Ageing and Cognitive Health, University of Exeter Medical School and College of Life and Environmental Sciences, St Luke's Campus, Exeter, UK.

Background: The aim was to investigate the comorbidity profile of people with dementia and examine the associations between severity of comorbidity, health-related quality of life (HRQoL) and quality of life (QoL).

Methods: The improving the experience of Dementia and Enhancing Active Life (IDEAL) cohort consisted of 1,547 people diagnosed with dementia who provided information on the number and type of comorbid conditions. Participants also provided ratings of their health-related and dementia-specific QoL. Read More

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http://dx.doi.org/10.1093/ageing/afy155DOI Listing
November 2018
1 Read

The development of a Core Outcome Set for medicines management interventions for people with dementia in primary care.

Age Ageing 2018 Nov 5. Epub 2018 Nov 5.

School of Pharmacy, Queen's University Belfast, Medical Biology Centre, Belfast, UK.

Background: people with dementia (PWD), and their carers, face challenges with medicines management activities. As interventions to support medicines management for PWD are developed, consideration must be given to the outcomes chosen to measure their effectiveness. A Core Outcome Set (COS) is a minimum set of outcomes to be measured in all trials in a particular clinical area, which seeks to reduce heterogeneity of outcome reporting across trials. Read More

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https://academic.oup.com/ageing/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/ageing/afy172DOI Listing
November 2018
4 Reads
3.642 Impact Factor

Age and Ageing to introduce a new category of paper: healthcare improvement science.

Age Ageing 2018 Nov 5. Epub 2018 Nov 5.

St Thomas' Hospital - Lambeth Palace Road, London, UK.

Age and Ageing is now inviting papers on healthcare improvement for older people. In this article we outline the nature and scope of healthcare improvement and reference improvement models and the tools and methods of improvement science. We emphasise the issues of sustainability, including scale and spread; evaluation - including associated ethical consideration and the involvement of patients and the public in healthcare improvement and associated research. Read More

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https://academic.oup.com/ageing/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/ageing/afy175DOI Listing
November 2018
2 Reads

The use of an electronic health record system reduces errors in the National Hip Fracture Database.

Age Ageing 2018 Nov 5. Epub 2018 Nov 5.

Department of Trauma and Orthopaedic Surgery, Cambridge University NHS Foundation Trust, Addenbrooke's Hospital, Hills Road, Cambridge, UK.

Aim: to compare the validity of data submitted from a UK level 1 trauma centre to the National Hip Fracture Database (NHFD) before and after the introduction of an electronic health record system (EHRS).

Patients And Methods: a total of 3224 records were reviewed from July 2009 to July 2017. 2,133 were submitted between July 2009 and October 2014 and 1,091 between October 2014 and July 2017, representing data submitted before and after the introduction of the EHRS, respectively. Read More

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https://academic.oup.com/ageing/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/ageing/afy177DOI Listing
November 2018
10 Reads

New horizons in hepatitis B and C in the older adult.

Age Ageing 2019 Jan;48(1):32-37

Gut Group, Division of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Ninewells Hospital and Medical school, Dundee, UK.

Hepatitis C (HCV) and hepatitis B (HBV), are blood-borne viruses that can cause acute hepatitis; but are clinically relevant because chronic infection is associated with development of cirrhosis and hepatocellular carcinoma. Both these viruses are becoming more common in the older population, due to the ageing of generations exposed to the risk factors associated with infection; intravenous drug use, multiple sexual partners and men who have sex with men. This review will cover the natural history and epidemiology of these infections as well as the revolution in drug therapy that now allows cure of HCV infection and complete control of HBV infection. Read More

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https://academic.oup.com/ageing/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/ageing/afy170DOI Listing
January 2019
3 Reads

Is retirement associated with physical health benefits? A longitudinal investigation with older New Zealanders.

Age Ageing 2018 Oct 31. Epub 2018 Oct 31.

School of Psychology, College of Humanities and Social Sciences, Massey University, New Zealand.

Objectives: the impact of retirement on physical health is an important focus of ageing research; however, research findings vary greatly. To investigate under what conditions retirement might benefit health, we examined physical functioning 8 years pre- and post-retirement.

Methods: using longitudinal data from the New Zealand Health, Work and Retirement Study, multiple linear trajectories of physical functioning were estimated. Read More

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http://fdslive.oup.com/www.oup.com/pdf/production_in_progres
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http://dx.doi.org/10.1093/ageing/afy176DOI Listing
October 2018
8 Reads

Community involvement, trust, and health-related outcomes among older adults in India: a population-based, multilevel, cross-sectional study.

Age Ageing 2019 Jan;48(1):87-93

Department of Social and Behavioral Science, Harvard School of Public Health, Boston, MA, USA; Harvard Center for Population and Development Studies, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

Objectives: this study examined whether individual and contextual measures of structural and cognitive social capital were associated with six health-related outcomes across older adults in India.

Methods: data were collected from a representative sample of adults aged 60 and above across India in 2011-12 (n = 9,174). Personal community involvement and having someone to trust represented individual measures of structural and cognitive social capital. Read More

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https://academic.oup.com/ageing/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/ageing/afy154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322503PMC
January 2019
2 Reads

Oesophageal ulcer due to a herbal remedy.

Age Ageing 2018 Oct 29. Epub 2018 Oct 29.

Gastroenterology and Hepatology Department, Fouad Khoury Hospital, Beirut, Lebanon.

Herbal-induced oesophageal lesions are rare. We report the case of an 85-year-old male who presented with cough and odynophagia. An upper endoscopy showed white deposit under the proximal oesophageal sphincter. Read More

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https://academic.oup.com/ageing/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/ageing/afy174DOI Listing
October 2018
7 Reads

Interventions to improve adherence to exercise therapy for falls prevention in community-dwelling older adults: systematic review and meta-analysis.

Age Ageing 2018 Oct 24. Epub 2018 Oct 24.

School of Allied Health, Faculty of Education and Health Sciences, Health Research Institute, University of Limerick, University of Limerick, Limerick, Ireland.

Background: exercise therapy is highly recommended for falls prevention in older adults; however, poor exercise adherence may limit treatment effectiveness.

Objective: to assess the effectiveness of interventions to improve exercise adherence for community-dwelling adults (aged over 65 years), at risk of falling.

Methods: eight databases were searched to identify randomised/quasi-randomised trials. Read More

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https://academic.oup.com/ageing/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/ageing/afy164DOI Listing
October 2018
6 Reads

A new dawn for sarcopenia.

Age Ageing 2019 Jan;48(1):2-3

Institute of Cardiovascular and Medical Sciences, University of Glasgow, 2rd floor New Lister Building, Glasgow Royal Infirmary, UK.

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https://academic.oup.com/ageing/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/ageing/afy171DOI Listing
January 2019
3 Reads

Enhancing our understanding of drinking in later life: qualitative data refreshes parts that other data cannot reach.

Authors:
Nina Fudge

Age Ageing 2019 Jan;48(1):3-5

Centre for Primary Care and Public Health, Blizard Institute, Queen Mary University of London, 58 Turner Street, London, UK.

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https://academic.oup.com/ageing/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/ageing/afy168DOI Listing
January 2019
2 Reads

When is Alzheimer's not dementia-Cochrane commentary on The National Institute on Ageing and Alzheimer's Association Research Framework for Alzheimer's Disease.

Age Ageing 2018 Oct 17. Epub 2018 Oct 17.

Cochrane Dementia and Cognitive Improvement Group, University of Oxford, UK.

Early 2018 saw the release of new diagnostic guidance on Alzheimer's disease from the National Institute on Ageing and the Alzheimer's Association (NIA-AA). This proposed research framework represents a fundamental change in how we think about Alzheimer's disease, moving from diagnosis based on clinical features to diagnosis based solely on biomarkers. These recommendations are contentious and have important implications for patients, clinicians, policy makers and the pharmaceutical industry. Read More

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http://dx.doi.org/10.1093/ageing/afy167DOI Listing
October 2018
1 Read

Fact Box decision support tools reduce decisional conflict about antibiotics for pneumonia and artificial hydration in advanced dementia: a randomized controlled trail.

Age Ageing 2019 Jan;48(1):67-74

University Research Priority Program 'Dynamics of Healthy Aging', University of Zurich, Zurich, Switzerland.

Background: fact Boxes are decision support tools that can inform about treatment effects.

Objectives: to test whether Fact Box decision support tools impacted decisional conflict, knowledge and preferences about the use of antibiotics and artificial hydration in advanced dementia.

Design: randomized controlled trial. Read More

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http://dx.doi.org/10.1093/ageing/afy149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322502PMC
January 2019
1 Read

Convergent validity of the electronic frailty index.

Age Ageing 2019 Jan;48(1):152-156

Academic Unit of Elderly Care & Rehabilitation, University of Leeds, Bradford Teaching Hospitals NHS Foundation Trust, Bradford, UK.

Background: the electronic frailty index (eFI) has been developed and validated using routine primary care electronic health record data. The focus of the original big data study was on predictive validity as a form of criterion validation. Convergent validity is a subtype of construct validity and considered a core component of the validity of a test. Read More

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https://academic.oup.com/ageing/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/ageing/afy162DOI Listing
January 2019
8 Reads

Sarcopenia: revised European consensus on definition and diagnosis.

Age Ageing 2019 Jan;48(1):16-31

Department of Medicine, Geriatric section, University of Verona, Verona, Italy.

Background: in 2010, the European Working Group on Sarcopenia in Older People (EWGSOP) published a sarcopenia definition that aimed to foster advances in identifying and caring for people with sarcopenia. In early 2018, the Working Group met again (EWGSOP2) to update the original definition in order to reflect scientific and clinical evidence that has built over the last decade. This paper presents our updated findings. Read More

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https://academic.oup.com/ageing/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/ageing/afy169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322506PMC
January 2019
2 Reads

Accessory navicular syndrome as a cause of foot pain during stroke rehabilitation.

Age Ageing 2019 Jan;48(1):159-161

Departments of Geriatric Medicine, Galway University Hospitals, Galway, Ireland.

Although usually asymptomatic, an accessory navicular bone can lead to medial foot pain, especially in younger people engaged in high impact sports. In many such cases, the tendon of posterior tibialis (which inverts and plantarflexes the foot) inserts onto the accessory bone resulting in greater strain on the tendon. In the present case, pain due to an accessory navicular bone first developed during stroke rehabilitation in a 69-year-old man. Read More

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https://academic.oup.com/ageing/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/ageing/afy165DOI Listing
January 2019
14 Reads

Relation of cigarette smoking and alcohol drinking in midlife with risk of cognitive impairment in late life: the Singapore Chinese Health Study.

Age Ageing 2019 Jan;48(1):101-107

Health Services and Systems Research, Duke-NUS Medical School, Singapore, Singapore.

Background: the relations of cigarette smoking and alcohol drinking with risk of cognitive impairment remain inconsistent.

Methods: to examine the independent and joint relations of smoking and alcohol drinking with cognitive impairment, we used data from 16,948 men and women, who had been followed-up for 16-23 (mean of 20) years as participants of the Singapore Chinese Health Study, a population-based prospective cohort. Data on smoking and alcohol drinking were collected at baseline (1993-98), when participants were aged 45-74 (mean 53) years. Read More

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https://academic.oup.com/ageing/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/ageing/afy166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322505PMC
January 2019
10 Reads
3.642 Impact Factor

Frequency, intensity and localization of pain as risk factors for frailty in older adults.

Age Ageing 2019 Jan;48(1):74-80

Department of Preventive Medicine and Public Health, School of Medicine, Universidad Autónoma de Madrid/IdiPaz, Madrid, Spain.

Background: the association between pain characteristics and frailty risk is uncertain.

Objective: to investigate the separate impact of the frequency, intensity and location of pain on frailty risk and its possible mechanisms.

Methods: prospective cohort of 1505 individuals ≥63 years followed between 2012 and 2015 in Spain. Read More

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https://academic.oup.com/ageing/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/ageing/afy163DOI Listing
January 2019
2 Reads

The association of under-weight and obesity with mortality after hip arthroplasty.

Age Ageing 2019 Jan;48(1):94-100

Institute of Health Services Research, Yonsei University, Seoul, Republic of Korea.

Background: although many studies have demonstrated the association between body mass index (BMI) and many diseases, there is little evidence of postoperative mortality after hip arthroplasty. The aim of this study was to evaluate the association between BMI and mortality after hip arthroplasty in the older population.

Methods: a total of 3,627 older patients who underwent hip arthroplasty from 2010 to 2013 were included. Read More

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https://academic.oup.com/ageing/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/ageing/afy161DOI Listing
January 2019
2 Reads

Detection and prevention of adverse drug reactions in multi-morbid older patients.

Age Ageing 2019 Jan;48(1):10-13

Department of Medicine Cork, University College Cork National University of Ireland, Munster, IE, Ireland.

Adverse drug reactions (ADRs) are a recognised unintentional form of iatrogenic harm, which commonly occur in older adults who have high levels of multi-morbidity and associated polypharmacy. Previous studies estimate that at least one in 10 hospitalised older patients will experience an ADR. While recent research indicates that this could be as high as 39% in hospitalised multi-morbid, older adults, up to two-thirds of these ADRs can be considered preventable and therefore potentially avoidable. Read More

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http://fdslive.oup.com/www.oup.com/pdf/production_in_progres
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http://dx.doi.org/10.1093/ageing/afy157DOI Listing
January 2019
2 Reads