2,580,252 results match your criteria Age Dordrecht Netherlands[Journal]


Normative references and clinical correlates of fetal umbilical artery Doppler indices in southwestern Nigeria.

Int J Gynaecol Obstet 2020 Jul 3. Epub 2020 Jul 3.

Department of Radiology, Lagos State University Teaching Hospital, Lagos, Nigeria.

Objective: To derive normative references for umbilical artery (UA) Doppler indices, including pulsatility index (PI), resistance index (RI), and systolic/diastolic (SD) ratio, for singleton pregnancies in Ile-Ife, Nigeria, and compare them with reference values from other populations.

Methods: A longitudinal study involving 415 women with a singleton fetus at 26-40 gestational weeks attending Obafemi Awolowo University Hospital, Ile-Ife, between July 2015 and March 2019. Fetal UA PI, RI, and SD ratio were measured every 4 weeks until delivery. Read More

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http://dx.doi.org/10.1002/ijgo.13294DOI Listing

The characteristics of palate and upper dental arch can be an anatomical marker for men with schizophrenia? Case-control study: Palate can be a marker for schizophrenia?

Spec Care Dentist 2020 Jul 3. Epub 2020 Jul 3.

Department of Stomatology, Universidade Federal do Paraná (UFPR), Curitiba, Brazil.

Aims: The aim of this study was to compare individuals with and without schizophrenia through the characteristics of the palate, such as width, length, depth, palate shape, and upper dental arch shape.

Methods And Results: The sample was divided into one case group (n = 45) and two control groups (n = 90; 45 individuals each group). Groups were paired by variables: sex, age, and malocclusion type. Read More

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http://dx.doi.org/10.1111/scd.12488DOI Listing

Effect of Covid-19 pandemic on stroke admission rates in a Norwegian population.

Acta Neurol Scand 2020 Jul 3. Epub 2020 Jul 3.

Department of Neurology, Akershus University Hospital, Lørenskog, Norway.

Objectives: There are concerns that public anxiety around Covid-19 discourages patients from seeking medical help. The aim of this study was to see how lockdown due to the pandemic affected the number of admissions of acute stroke.

Methods: All patients discharged from Akershus University Hospital with a diagnosis of transient ischemic attack (TIA) or acute stroke were identified by hospital chart review. Read More

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http://dx.doi.org/10.1111/ane.13307DOI Listing

Exposure to Meconium-Stained Amniotic Fluid and Long-Term Neurological-Related Hospitalizations throughout Childhood.

Am J Perinatol 2020 Jul 3. Epub 2020 Jul 3.

Department of Obstetrics and Gynecology, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

Objective:  This study aimed to investigate the possible impact of meconium-stained amniotic fluid (MSAF) on the occurrence of neurological-related hospitalizations throughout childhood and adolescence.

Study Design:  In this population-based cohort analysis, all singleton deliveries occurring between 1991 and 2014 at the Soroka University Medical center were included and the long-term neurological-related hospitalizations were compared between children with and without MSAF during their delivery. A Kaplan-Meier survival analysis was constructed for the evaluation of cumulative hospitalization rate due to neurological morbidity over the 18 years of follow-up, and a Cox proportional hazards model was used to study the independent association between MSAF and childhood neurological morbidity while controlling for potential confounders. Read More

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http://dx.doi.org/10.1055/s-0040-1713863DOI Listing

Receipt of Proton-Pump Inhibitors during Pregnancy and Risk for Preeclampsia.

Am J Perinatol 2020 Jul 3. Epub 2020 Jul 3.

Department of Obstetrics and Gynecology, College of Physicians and Surgeons, Columbia University, New York, New York.

Objective:  This study aimed to determine whether receiving a proton-pump inhibitor (PPI) prescription during pregnancy was associated with decreased risk for preeclampsia.

Study Design:  The Truven Health MarketScan database was used to determine whether receiving a PPI prescription was associated with risk for preeclampsia. Risk for preeclampsia was evaluated based on the presence or absence of receiving a PPI prescription (1) any time during pregnancy, and 2) individually during the 1st, 2nd, and 3rd trimesters. Read More

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http://dx.doi.org/10.1055/s-0040-1713864DOI Listing

Nasogastric versus Orogastric Bolus Tube Feeding in Preterm Infants: Pilot Randomized Clinical Trial.

Am J Perinatol 2020 Jul 3. Epub 2020 Jul 3.

Neonatal Intensive Care Unit, Mansoura University Children's Hospital, Mansoura, Egypt.

Objective:  According to the most recent metanalysis, the best way to establish safe enteral feeding in preterm babies using nasogastric or orogastric tubes is still not well understood. This study aimed to determine the effects of bolus nasal tubes versus bolus orogastric tubes on the time required to reach full enteral feeding in preterm infants, as well as to compare the incidence rates of adverse events including nonintentional removal or displacement of the feeding tube, aspiration pneumonia/pneumonitis, apnea, necrotizing enterocolitis, gastric residual, and growth parameters between the studied cohort of preterm infants.

Study Design:  We conducted an unblinded pilot randomized clinical trial on hemodynamically stable preterm infants (>28 weeks) recruited from level 2 neonatal intensive care unit at Mansoura University Children's Hospital from June 2015 to May 2017. Read More

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http://dx.doi.org/10.1055/s-0040-1713865DOI Listing

Efficient T cell compartment in HIV+ patients receiving orthotopic liver transplant and immunosuppressive therapy.

J Infect Dis 2020 Jul 4. Epub 2020 Jul 4.

Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia, Modena, Italy.

Background And Aims: In patients undergoing orthotopic liver transplant (OLT), immunosuppressive (IS) treatment is mandatory and infections are leading causes of morbidity/mortality. Thus, it is essential to understand the functionality of cell-mediated immunity after OLT. The aim of the study was to identify changes in T cell phenotype and polyfunctionality in HIV+ and HIV- patients treated with IS after OLT. Read More

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http://dx.doi.org/10.1093/infdis/jiaa395DOI Listing

Cultural differences in susceptibility to stereotype threat: France vs. India.

J Gerontol B Psychol Sci Soc Sci 2020 Jul 4. Epub 2020 Jul 4.

Aix Marseille Univ, LPC, CNRS, Marseille, France.

Objectives: Negative aging stereotypes make older adults perform below their true potential in a number of cognitive domains. This phenomenon, known as Age-Based Stereotype Threat, is currently viewed as a powerful factor contributing to an overestimation of cognitive decline in normal aging. However, age-based stereotype threat has been investigated almost exclusively in Western countries. Read More

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http://dx.doi.org/10.1093/geronb/gbaa087DOI Listing

Pregnancy per- and polyfluoroalkyl substance concentrations and postpartum health in Project Viva, a prospective cohort.

J Clin Endocrinol Metab 2020 Jul 4. Epub 2020 Jul 4.

Department of Environmental Health, Harvard T.H. Chan School of Public Health; and Department of Epidemiology, Harvard T.H. Chan School of Public Health; and Division of Women's Health, Department of Medicine, Connors Center for Women's Health and Gender Biology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

Context: Per- and polyfluoroalkyl substances (PFAS) are environmental chemicals linked to weight gain and type 2 diabetes.

Objective: We examined the extent to which PFAS plasma concentrations during pregnancy were associated with postpartum anthropometry and biomarkers.

Design, Patients, Measures: We studied women recruited between 1999-2002 in the Project Viva prospective cohort with pregnancy plasma concentrations of PFAS, including perfluorooctanesulfonic acid (PFOS), perfluorooctanoic acid (PFOA), and 2-(N-ethyl-perfluorooctane sulfonamide) acetic acid (EtFOSAA). Read More

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http://dx.doi.org/10.1210/clinem/dgaa431DOI Listing

Earlier radiosurgery leads to better pain relief and less medication usage for trigeminal neuralgia patients: an international multicenter study.

J Neurosurg 2020 Jul 3:1-8. Epub 2020 Jul 3.

1Department of Neurosurgery, New York University Langone Medical Center, New York, New York.

Objective: Trigeminal neuralgia (TN) is a chronic pain condition that is difficult to control with conservative management. Furthermore, disabling medication-related side effects are common. This study examined how stereotactic radiosurgery (SRS) affects pain outcomes and medication dependence based on the latency period between diagnosis and radiosurgery. Read More

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http://dx.doi.org/10.3171/2020.4.JNS192780DOI Listing

Fine configuration of the dural fibrous network and the extradural neural axis compartment in the jugular foramen: an epoxy sheet plastination and confocal microscopy study.

J Neurosurg 2020 Jul 3:1-11. Epub 2020 Jul 3.

1Department of Anatomy and.

Objective: The extradural neural axis compartment (EDNAC) is an adipovenous zone that is located between the meningeal (ML) and endosteal (EL) layers of the dura mater and has been minimally investigated in the jugular foramen (JF) region. In this study, the authors aimed to explore the fine architecture of the EDNAC within the JF and evaluate whether the EDNAC can be used as a component for JF compartmentalization.

Methods: A total of 46 cadaveric heads (31 male, 15 female; age range 54-96 years) and 30 dry skulls were examined in this study. Read More

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http://dx.doi.org/10.3171/2020.4.JNS20811DOI Listing

The utility of brain biopsy in pediatric cryptogenic neurological disease.

J Neurosurg Pediatr 2020 Jul 3:1-8. Epub 2020 Jul 3.

Departments of1Neurosurgery.

Objective: The authors' aim was to characterize a single-center experience of brain biopsy in pediatric cryptogenic neurological disease.

Methods: The authors performed a retrospective review of consecutive brain biopsies at a tertiary pediatric neurosciences unit between 1997 and 2017. Children < 18 years undergoing biopsy for neurological pathology were included. Read More

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http://dx.doi.org/10.3171/2020.4.PEDS19783DOI Listing

Endoscopic aqueductal stenting in the management of pediatric hydrocephalus.

J Neurosurg Pediatr 2020 Jul 3:1-7. Epub 2020 Jul 3.

1Department of Pediatric Neurosurgery, Hôpital Necker, Assistance Publique Hôpitaux de Paris, Université de Paris, France; and.

Objective: Pediatric patients with long-term shunts may experience specific complications related to the segregation of the supra- and infratentorial spaces along with different pressure regimens, leading to either mesencephalic syndromes during shunt dysfunction or isolated fourth ventricle (IFV). An accepted treatment to reestablish normal CSF pathways and reequilibrate the transtentorial pressures is endoscopic aqueductal stenting (EAS) to avoid restenosis. In the present paper, the authors studied children treated with EAS during the last decade for both IFV and obstructive hydrocephalus, evaluated its impact on the course of the disease, and identified prognostic factors for EAS success. Read More

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http://dx.doi.org/10.3171/2020.4.PEDS20144DOI Listing

Lack of impact of polycystic kidney disease on the outcome of aneurysmal subarachnoid hemorrhage: a matched case-control study.

J Neurosurg 2020 Jul 3:1-8. Epub 2020 Jul 3.

1Neurosurgery of NeuroCenter, Kuopio University Hospital and University of Eastern Finland, Kuopio.

Objective: The authors set out to study whether autosomal dominant polycystic kidney disease (ADPKD), an established risk factor for intracranial aneurysms (IAs), affects the acute course and long-term outcome of aneurysmal subarachnoid hemorrhage (aSAH).

Methods: The outcomes of 32 ADPKD patients with aSAH between 1980 and 2015 (median age 43 years; 50% women) were compared with 160 matched (age, sex, and year of aSAH) non-ADPKD aSAH patients in the prospectively collected Kuopio Intracranial Aneurysm Patient and Family Database.

Results: At 12 months, 75% of the aSAH patients with ADPKD versus 71% of the matched-control aSAH patients without ADPKD had good outcomes (Glasgow Outcome Scale score 4 or 5). Read More

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http://dx.doi.org/10.3171/2020.4.JNS20544DOI Listing

Outcomes in single-level posterior cervical spine surgeries performed in the sitting and prone positions.

J Neurosurg Spine 2020 Jul 3:1-7. Epub 2020 Jul 3.

Departments of1Neurologic Surgery and.

Objective: The sitting or semisitting position in neurosurgery allows for several technical advantages, including improved visualization of the surgical field. However, it has also been associated with an increased risk of venous air embolisms and positioning-related complications that limit its commonplace adoption. The authors report a large, single-center series of cervical spine procedures performed with patients in the sitting or prone position in order to assess the perceived risk of intraoperative and postoperative complications associated with the sitting position. Read More

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http://dx.doi.org/10.3171/2020.4.SPINE191323DOI Listing

Long-term follow-up of neurosurgical outcomes for adult patients in Uganda with traumatic brain injury.

J Neurosurg 2020 Jul 3:1-11. Epub 2020 Jul 3.

2Department of Neurosurgery, Stanford University, Palo Alto, California.

Objective: Traumatic brain injury (TBI) is a major cause of mortality and morbidity in Uganda and other low- and middle-income countries (LMICs). Due to the difficulty of long-term in-person follow-up, there is a paucity of literature on longitudinal outcomes of TBI in LMICs. Using a scalable phone-centered survey, this study attempted to investigate factors associated with both mortality and quality of life in Ugandan patients with TBI. Read More

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http://dx.doi.org/10.3171/2020.4.JNS193092DOI Listing

Trends and characteristics of infection-related hospital admissions in multiple sclerosis patients in Southwest Finland in 2009-2018.

Mult Scler Relat Disord 2020 Jun 23;44:102328. Epub 2020 Jun 23.

Division of Clinical Neurosciences, Turku University Hospital, Turku, Finland; Department of Clinical Neurosciences, University of Turku, Turku, Finland.

Background: Multiple sclerosis (MS) patients are at increased risk for infections. The aim of this study was to investigate the trends in hospital admissions of patients with MS and to identify the factors predisposing to infection-related admissions.

Methods: Hospital admissions with MS as a primary or an auxiliary diagnosis in the hospital district of Southwest Finland in 2009-2018 were searched and MS patients with infection admissions compared with other MS patients in the hospital district. Read More

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http://dx.doi.org/10.1016/j.msard.2020.102328DOI Listing

Cerebral hemodynamics in patients with multiple sclerosis.

Mult Scler Relat Disord 2020 Jun 17;44:102309. Epub 2020 Jun 17.

Neurological Clinic, Department of Experimental and Clinical Medicine, Marche Polytechnic University, Via Conca 71, 60020 Ancona, Italy.

Background And Purpose: Multiple sclerosis (MS) is a demyelinating disease of the central nervous system. Although the currently predominant view is that of an autoimmune inflammatory condition, changes in brain vasculature can occur and contribute to pathophysiology. The aim of this study was to evaluate cerebral hemodynamics in patients with MS and explore its relationship with disease status. Read More

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http://dx.doi.org/10.1016/j.msard.2020.102309DOI Listing

A case of dwarfism in 6th century Italy: Bioarchaeological assessment of a hereditary disorder.

Int J Paleopathol 2020 Jun 30;30:110-117. Epub 2020 Jun 30.

Laboratories of Physical Anthropology and Ancient DNA, Department of Cultural Heritage, University of Bologna, via Degli Ariani 1, 48121, Ravenna, Italy; Department of Human Evolution, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103, Leipzig, Germany.

Objective: The skeletal remains of a short-statured individual (T17) are described and a differential diagnosis performed to determine the etiology of the condition.

Materials: An individual considered pathologically short in stature was discovered in the burial site of Piazza XX Settembre, Modena (northern Italy).

Methods: Morphological and morphometric analyses were performed, and T17 was compared to dwarfs from other localities and periods and to the adult female population from the same site. Read More

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http://dx.doi.org/10.1016/j.ijpp.2020.03.003DOI Listing

Socioeconomic consequences of drug-resistant epilepsy in an adult cohort from southern India.

Epilepsy Behav 2020 Jun 30;110:107173. Epub 2020 Jun 30.

Department of Neurology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India. Electronic address:

Objective: The objective of this study was to describe the socioeconomic consequences of drug-resistant epilepsy (DRE).

Methods: This study comprised 132 (equal males and females) consecutive patients aged ≥18 years, who fulfilled the International League Against Epilepsy (ILAE) definition for DRE, prospectively seen in a tertiary care center in South India. We used a structured questionnaire to gather relevant information. Read More

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http://dx.doi.org/10.1016/j.yebeh.2020.107173DOI Listing

Development and validation of the VISAGE AmpliSeq basic tool to predict appearance and ancestry from DNA.

Forensic Sci Int Genet 2020 Jun 20;48:102336. Epub 2020 Jun 20.

Institute of Legal Medicine, Medical University of Innsbruck, Innsbruck, Austria; Forensic Science Program, The Pennsylvania State University, University Park, PA, USA. Electronic address:

Forensic DNA phenotyping is gaining interest as the number of applications increases within the forensic genetics community. The possibility of providing investigative leads in addition to conventional DNA profiling for human identification provides new insights into otherwise "cold" police investigations. The ability of reporting on the bio-geographical ancestry (BGA), appearance characteristics and age based on DNA obtained from a crime scene sample of an unknown donor makes the exploration of such markers and the development of new methods meaningful for criminal investigations. Read More

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http://dx.doi.org/10.1016/j.fsigen.2020.102336DOI Listing

Analysis of adjunctive serological detection to nucleic acid test for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection diagnosis.

Int Immunopharmacol 2020 Jun 26;86:106746. Epub 2020 Jun 26.

Department of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, PR China. Electronic address:

Background: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused coronavirus disease 2019 (COVID-19) epidemic in China, December 2019. The clinical features and treatment of COVID-19 patients remain largely elusive. However, accurate detection is required for SARS-CoV-2 infection diagnosis. Read More

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http://dx.doi.org/10.1016/j.intimp.2020.106746DOI Listing

Burden of diabetic kidney disease among persons with type 2 diabetes mellitus registered in a tertiary care center, Puducherry.

Diabetes Metab Syndr 2020 Jun 23;14(5):991-993. Epub 2020 Jun 23.

Department of Preventive and Social Medicine, JIPMER, India. Electronic address:

Background & Aims: To determine burden of diabetic kidney disease (DKD) and estimate yield and number needed to screen (NNS) in a tertiary diabetes care center.

Methods: DKD was diagnosed if estimated Glomerular Filtration Rate (eGFR) < 60 ml/min/1.73 m or Urinary Albumin Creatinine Ratio (UACR) ≥30 mg/g in two urine samples. Read More

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http://dx.doi.org/10.1016/j.dsx.2020.06.037DOI Listing

Clinicopathological features of 50 mismatch repair (MMR)-deficient endometrial carcinomas, tested by immunohistochemistry: A single institutional feasibility study, India.

Ann Diagn Pathol 2020 Jun 20;47:151558. Epub 2020 Jun 20.

Department of Radiation Oncology (Gynecology, Disease Management group), Tata Memorial Hospital, HBNI University, Mumbai, India.

There are few comprehensive studies from Asia on clinicopathologic features of mismatch repair (MMR)-deficient endometrial carcinomas, including rarely from our country. One hundred and four cases of endometrial carcinomas were tested for four MMR proteins by immunohistochemistry. Among 50 MMR-deficient (MMRd) tumors(48%), age-range was 27-68 years(median = 53) and tumor size(n = 34) varied from 1. Read More

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http://dx.doi.org/10.1016/j.anndiagpath.2020.151558DOI Listing

Novel FEMASK-score, a histopathologic assessment for destructive Charcot neuropathic arthropathy, reveals intraneural vasculopathy and correlates with progression and best treatment.

Ann Diagn Pathol 2020 Mar 23;47:151509. Epub 2020 Mar 23.

Penn State College of Medicine, Penn State Health, Milton S. Hershey Medical Center, Hershey, PA, USA; Department of Orthopedic Surgery, Hershey, PA, USA.

Background: Charcot neuropathic arthropathy is a debilitating, rapidly destructive degenerative joint disease that occurs in diabetic, neuropathic midfoot. Clinicoradiologic assessment for Charcot neuropathic arthropathy previously relied on Eichenholtz stage. There is limited histopathologic data on this entity. Read More

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http://dx.doi.org/10.1016/j.anndiagpath.2020.151509DOI Listing

Attributable risks associated with hospital outpatient visits for mental disorders due to air pollution: A multi-city study in China.

Environ Int 2020 Jun 30;143:105906. Epub 2020 Jun 30.

Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.

Aim: To determine the associations between outdoor air pollution and hospital outpatient visits for mental disorders in China.

Methods: We obtained data of 111,842 hospital outpatient visits for mental disorders from the largest hospitals of 13 cities, China, between January 01, 2013 and December 31, 2015. We collected air pollutant data including particulate matter ≤2. Read More

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http://dx.doi.org/10.1016/j.envint.2020.105906DOI Listing

Fine particulate matter constituents and cause-specific mortality in China: A nationwide modelling study.

Environ Int 2020 Jun 30;143:105927. Epub 2020 Jun 30.

Institute for Environmental and Climate Research, Jinan University, Guangzhou 511443, China; Guangdong-Hongkong-Macau Joint Laboratory of Collaborative Innovation for Environmental Quality, Guangzhou 511443, China; JNU-QUT Joint Laboratory for Air Quality Science and Management, Jinan University, Guangzhou 511443, China. Electronic address:

Background: Fine particulate matter (with aerodynamic diameter ≤2.5 µm, PM) causes huge disease burden worldwide. However, evidence is still inadequate and inconsistent on the relationships between PM constituents and mortality, especially in low resource settings. Read More

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http://dx.doi.org/10.1016/j.envint.2020.105927DOI Listing

Spinal anesthesia in surgical treatment of lumbar spine tumors.

Clin Neurol Neurosurg 2020 Jun 20;196:106023. Epub 2020 Jun 20.

Okan University, Department of Neurosurgery, Istanbul, Turkey.

Objective: This study aims to show the feasibility of spinal anesthesia in lumbar spinal tumor surgery; share our data and experience.

Patients And Methods: A retrospective review of 14 patients with high risk for general anesthesia due to severe comorbidities was carried out. Patients who underwent surgeries under spinal anesthesia for lumbar vertebral column or spinal cord tumors at a single center between 2007-2019 were evaluated. Read More

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http://dx.doi.org/10.1016/j.clineuro.2020.106023DOI Listing

Surgical outcomes in traumatic brain injuries with bilateral mass occupying lesions. Analysis of prognostic factors.

Clin Neurol Neurosurg 2020 Jun 20;196:106017. Epub 2020 Jun 20.

Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka 560029, India. Electronic address:

Introduction: Traumatic brain injury is a silent epidemic with major impacts on national productivity as it affects the economically productive age group. Bilateral injuries are usually severe with no clearly defined predictors of outcome as per current available literature.

Methods: We retrospectively assessed 102 consecutive cases of post traumatic intracranial mass lesions operated bilaterally, either simultaneously or sequentially, between January 2011 and April 2019. Read More

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http://dx.doi.org/10.1016/j.clineuro.2020.106017DOI Listing

Development of the Jordanian Arabic early speech perception test.

Int J Pediatr Otorhinolaryngol 2020 May 25;136:110130. Epub 2020 May 25.

Division of Speech Pathology and Audiology, Research Institute of Audiology & Speech Pathology, Collage of Natural Sciences, Hallym University, Chuncheon, South Korea. Electronic address:

Introduction: The Early Speech Perception (ESP) test has been previously used to assess speech perception skills in young hearing-impaired children. As the Arabic language is known to be diglossic, the purpose of this study was to develop a Colloquial Jordanian Arabic version (JAESP) of the ESP test and to check its usefulness.

Methods: The JAESP test encompasses four categories: detection of speech sounds, speech pattern perception, disyllabic word identification, and monosyllabic word identification. Read More

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http://dx.doi.org/10.1016/j.ijporl.2020.110130DOI Listing

Collaboration increases children's normative concern for fairness.

Authors:
John Corbit

J Exp Child Psychol 2020 Jun 30;198:104887. Epub 2020 Jun 30.

Department of Psychology and Neuroscience, Dalhousie University, Halifax, Nova Scotia B3H 4J1, Canada. Electronic address:

Collaboration increases equity in young children, but whether this precocious equity has a normative foundation or is primarily an interpersonal concern between collaborators remains an open question. Participants in this study were 3- to 7-year-old children (N = 104) from a rural community in Canada. In a novel third-party intervention game, children could intervene against inequitable sharing between third parties who earned resources collaboratively or individually. Read More

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http://dx.doi.org/10.1016/j.jecp.2020.104887DOI Listing

Disruption of oligodendrocyte progenitor cells is an early sign of pathology in the triple transgenic mouse model of Alzheimer's disease.

Neurobiol Aging 2020 Jun 7;94:130-139. Epub 2020 Jun 7.

Institute of Biomedical and Biomolecular Sciences, School of Pharmacy and Biomedical Sciences, University of Portsmouth, Portsmouth, UK. Electronic address:

There is increasing evidence that myelin disruption is related to cognitive decline in Alzheimer's disease (AD). In the CNS, myelin is produced by oligodendrocytes, which are generated throughout life by adult oligodendrocyte progenitor cells (OPCs), also known as NG2-glia. To address whether alterations in myelination are related to age-dependent changes in OPCs, we analyzed NG2 and myelin basic protein (MBP) immunolabelling in the hippocampus of 3×Tg-AD mice at 6 and 24 months of age, compared with non-Tg age-matched controls. Read More

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http://dx.doi.org/10.1016/j.neurobiolaging.2020.05.016DOI Listing

Extended-release naltrexone versus buprenorphine-naloxone to treat opioid use disorder among black adults.

Addict Behav 2020 Jun 18;110:106514. Epub 2020 Jun 18.

Columbia University Irving Medical Center, Department of Psychiatry and New York State Psychiatric Institute, 1051 Riverside Dr., New York, NY 10032, United States.

Few studies examine the effectiveness of treatments for opioid use disorder (OUD) among Black individuals despite recent evidence suggesting opioid overdose death rates are, in some cases, highest and increasing at a faster rate among Black people compared to other racial/ethnic groups. This secondary analysis study investigated treatment preference, retention, and relapse rates amongst a subgroup of 73 Black participants with OUD (81% male, mean age 39.05, SD = 11. Read More

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http://dx.doi.org/10.1016/j.addbeh.2020.106514DOI Listing

The 5 and 11 Factor Modified Frailty Indices are Equally Effective at Outcome Prediction Using TQIP.

J Surg Res 2020 Jun 30;255:456-462. Epub 2020 Jun 30.

Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama.

Background: The 5-factor modified frailty index (mFI-5) and the 11-factor modified frailty index (mFI-11) are equally effective in predicting adverse outcomes in the American College of Surgeons National Surgical Quality Improvement Program database. The similarly structured American College of Surgeons Trauma Quality Improvement Program (TQIP) database has not been studied with these two frailty indices. We hypothesized that the mFI-5 and mFI-11 could similarly predict adverse outcomes with TQIP data. Read More

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http://dx.doi.org/10.1016/j.jss.2020.05.090DOI Listing

Predictive Model for Operative Intervention after Blunt Abdominal Trauma in Children with Equivocal CT Findings: A Pilot Study.

J Surg Res 2020 Jun 30;255:449-455. Epub 2020 Jun 30.

Department of Pediatric Surgery, John R. Oishei Children's Hospital, Buffalo, New York; Department of Surgery, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, Buffalo, New York.

Background: To study the clinical and radiologic factors predicting the need for surgical intervention after blunt abdominal trauma (BAT) in children with equivocal computed tomography (CT) scan findings.

Methods: We performed a retrospective review of the trauma database at our level I pediatric trauma center between 2011 and 2019. We selected patients with BAT and equivocal findings for surgical intervention on CT scan. Read More

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http://dx.doi.org/10.1016/j.jss.2020.05.088DOI Listing

Association between Enterocyte Injury and Mortality in Patients on Hemodialysis Who Underwent Cardiac Surgery: An Exploratory Study.

J Surg Res 2020 Jun 30;255:420-427. Epub 2020 Jun 30.

Department of Anesthesiology and Intensive Care Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.

Background: Intestinal ischemia and enterocyte injury are significant causes of death after cardiac surgery. Hemodialysis is a well-known risk factor for intestinal ischemia. However, the relationship between enterocyte injury and mortality is unclear. Read More

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http://dx.doi.org/10.1016/j.jss.2020.05.091DOI Listing

Personal, professional and workplace factors associated with burnout in Jordanian midwives: A national study.

Midwifery 2020 Jun 25;89:102786. Epub 2020 Jun 25.

Maternal, Newborn and Families Research Collaborative, Menzies Institute of Health Queensland, Griffith University, Brisbane, Australia. Electronic address:

Objective: To investigate the prevalence of burnout and explore associated socio-demographic and work-related factors among Jordanian midwives.

Design: A cross-sectional survey design. The survey tool included the Copenhagen Burnout Inventory (CBI) and socio-demographic and work-related data forms. Read More

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http://dx.doi.org/10.1016/j.midw.2020.102786DOI Listing

Safety and efficacy of T-DM1 in patients with advanced HER2-positive breast cancer The Royal Marsden experience.

Cancer Treat Res Commun 2020 Jun 27;24:100188. Epub 2020 Jun 27.

Medical Oncology, Royal Marsden Hospital, Royal Marsden Hospital, Downs Road, Sutton SM25PT, United Kingdom. Electronic address:

Background: Ado-trastuzumab emtansine (T-DM1) is standard of care for patients with advanced HER2+ breast cancer who relapse within 6 months of adjuvant trastuzumab or progress on first-line anti-HER2 therapy. We evaluated its safety and efficacy in our real-world population.

Methods: We identified patients on T-DM1 from 01/01/2014 to 12/03/2018 from our electronic records. Read More

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http://dx.doi.org/10.1016/j.ctarc.2020.100188DOI Listing

Risk factors for the recurrence of convulsions with mild gastroenteritis in children.

Seizure 2020 Jun 16;80:192-195. Epub 2020 Jun 16.

Department of Neurology, Guangzhou Women and Children's Medical Center, Guangzhou, China. Electronic address:

Purpose: To identify risk factors for the recurrence of convulsions with mild gastroenteritis (CwG) in children.

Methods: Altogether, 613 children with CwG admitted to Children's Hospital of Shanxi Province from January 2010 to December 2015 were selected, their clinical data were retrospectively analyzed, and patients were followed up for 4-10 years. Risk factors for the recurrence of CwG were analyzed based on the clinical characteristics of the children. Read More

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http://dx.doi.org/10.1016/j.seizure.2020.06.016DOI Listing

Age-related changes in the association of resting-state fMRI signal variability and global functional connectivity in non-demented healthy people.

Psychiatry Res 2020 Jun 27;291:113257. Epub 2020 Jun 27.

Division of Interdisciplinary Medicine and Biotechnology, Beth Israel Deaconess Medical Center / Harvard Medical School, Boston, MA, United States; Institute of Brain Sciences, National Yang-Ming University, Taipei, Taiwan; Digital Medicine Center, National Yang-Ming University, Taipei, Taiwan. Electronic address:

Research suggests that the aging relates to variability of resting-state fMRI (rs-fMRI) signal and the functional connectivity. However, the association between the spatial and temporal activity of resting-state fMRI signal was less documented. We recruited 477 healthy Han Chinese participants, who were separated into young, middle and old groups to investigate the relationship between the variability and global functional connectivity (gFC) in different age ranges using standard deviation (SD) of time series and gFC, respectively. Read More

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http://dx.doi.org/10.1016/j.psychres.2020.113257DOI Listing

Factors associated with 30-day readmissions following medical hospitalizations among Medicaid beneficiaries with schizophrenia, bipolar disorder, and major depressive disorder.

Psychiatry Res 2020 Jun 1;291:113168. Epub 2020 Jun 1.

Department of Psychiatry, Fetter Health Care Network, Charleston, SC, USA.

While evidence suggests that adults with serious mental illness have an elevated rate of 30-day readmissions after medical hospitalizations, most studies are of patients who are privately insured or Medicare beneficiaries, and little is known about the differential experiences of people with schizophrenia, bipolar disorder, and major depression. We used the Truven Health Analytics MarketScan® Medicaid Multi-State Database to study 43,817 Medicaid enrollees from 11 states, age 18-64, who were discharged from medical hospitalizations in 2011. Our outcome was unplanned all-cause readmissions within 30 days of discharge. Read More

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http://dx.doi.org/10.1016/j.psychres.2020.113168DOI Listing

Acute myocardial infarction under-diagnosis and mortality in a Tanzanian emergency department: A prospective observational study.

Am Heart J 2020 Jun 5;226:214-221. Epub 2020 Jun 5.

Duke Global Health Institute, 310 Trent Drive, Durham, NC; Division of Cardiology, Duke University School of Medicine, 2301 Erwin Rd, Durham, NC; Duke Clinical Research Institute, 300 W Morgan St, Durham, NC.

Background: Growing evidence suggests that under-diagnosis of acute myocardial infarction (AMI) may be common in sub-Saharan Africa. Prospective studies of routine AMI screening among patients presenting to emergency departments in sub-Saharan Africa are lacking. Our objective was to determine the prevalence of AMI among patients in a Tanzanian emergency department. Read More

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http://dx.doi.org/10.1016/j.ahj.2020.05.017DOI Listing

The questionable efficacy of manualized psychological treatments for distressed breast cancer patients: An individual patient data meta-analysis.

Clin Psychol Rev 2020 Jun 16;80:101883. Epub 2020 Jun 16.

Department of Psychological Sciences, University of Liverpool, Whelan Building, Liverpool, UK; Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool, UK.

Previous meta-analyses conclude that psychological treatments are efficacious for emotional distress in breast cancer (BCa). However, the practical relevance of these meta-analyses is questionable; none focused specifically on clinically distressed patients or whether treatment effects were clinically significant. In a two-stage individual patient data (IPD) meta-analysis of 17 randomized controlled trials of manualized psychological treatments in BCa, we evaluated treatment efficacy in distressed BCa patients (n = 1591) using clinical significance and effect size analyses. Read More

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http://dx.doi.org/10.1016/j.cpr.2020.101883DOI Listing

Gene-gene and gene-lifestyle interactions of AKAP11, KCNMA1, PUM1, SPTBN1, and EPDR1 on osteoporosis risk in middle-aged adults.

Nutrition 2020 May 19;79-80:110859. Epub 2020 May 19.

Department of Environmental Engineering, Hoseo University, Asan, South Korea.

Objectives: Osteoporosis is associated with genetic and environmental factors. The aim of this article was to determine how the polygenic risk scores (PRS) of genetic variants that affect osteoporosis and its related signaling interact with the lifestyle of middle-aged adults.

Methods: The study examined 8845 participants from Ansan/Ansung cohorts. Read More

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http://dx.doi.org/10.1016/j.nut.2020.110859DOI Listing

Evolution of histomorphologic, cytogenetic, and genetic abnormalities in an untreated patient with MIRAGE syndrome.

Cancer Genet 2020 Jun 14;245:42-48. Epub 2020 Jun 14.

Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Abramson Research Center, Room 716D, 3615 Civic Center Blvd., Philadelphia, PA 19104, United States; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, United States. Electronic address:

Gain of function variants in SAMD9 cause MIRAGE syndrome, a rare Mendelian disorder that results in myeloid dysplastic syndrome (MDS), poor immune response, restricted growth, adrenal insufficiency, ambiguous genitalia, feeding difficulties and most often significantly reduced lifespan. In this study, we describe histomorphologic and genetic changes occurring in serial bone marrow measurements in a patient with MIRAGE syndrome and untreated MDS of 9 years. Histomorphological analysis during childhood showed progressive hypocellularity with erythroid and megakaryocytic dysplasia and cytogenetic testing demonstrated monosomy 7. Read More

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http://dx.doi.org/10.1016/j.cancergen.2020.06.002DOI Listing

Characteristics and outcomes of lung cancer in solid organ transplant recipients.

Lung Cancer 2020 Jun 20;146:297-302. Epub 2020 Jun 20.

Columbia University Medical Center, Herbert Irving Pavilion, 161 Fort Washington Avenue, New York, NY 10032, United States; Department of Medicine, Columbia University Medical Center, United States. Electronic address:

Objectives: Lung cancer is the third most common malignancy that develops in patients following solid organ transplantation and is the leading cause of cancer deaths in the general population. The aims of this study are to examine the characteristics of patients who developed lung cancer following solid organ transplantation at our institution and to compare their outcomes to those of lung cancer patients without a history of transplant.

Materials And Methods: We performed a single-institution retrospective study of 44 solid organ transplant recipients who developed lung cancer and compared their characteristics to a cohort of 74 lung cancer patients without a history of transplant. Read More

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http://dx.doi.org/10.1016/j.lungcan.2020.06.018DOI Listing

Post-mortem estimation of gestational age and maturation of new-borns by CT examination of clavicle length, femoral length and femoral bone nuclei.

Forensic Sci Int 2020 Jun 24;314:110391. Epub 2020 Jun 24.

Institute of Legal Medicine, Medical Faculty, University of Cologne, Melatengürtel 60/62, 50823 Cologne, Germany.

Various parameters can be used for the estimation of gestational age and maturity with arising challenges in the assessment of decomposed bodies. In order to assess gestational age and thus maturity, the study measured the femoral length, the diameter of the distal femoral epiphysis and the presence of the proximal tibial epiphysis compared to a known clavicle length. The resulting gestational ages were compared and statistically evaluated. Read More

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http://dx.doi.org/10.1016/j.forsciint.2020.110391DOI Listing

Aesthetics and morality judgments share cortical neuroarchitecture.

Cortex 2020 May 15;129:484-495. Epub 2020 May 15.

Zurich Center for Neuroeconomics, Department of Economics, University of Zurich, Zurich, Switzerland. Electronic address:

Philosophers have predominantly regarded morality and aesthetics judgments as fundamentally different. However, whether this claim is empirically founded has remained unclear. In a novel task, we measured brain activity of participants judging the aesthetic beauty of artwork or the moral goodness of actions depicted. Read More

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http://dx.doi.org/10.1016/j.cortex.2020.04.018DOI Listing

Chest-CT findings of COVID-19 in patients with pre-existing malignancies; a pictorial review.

Clin Imaging 2020 Jun 9;67:121-129. Epub 2020 Jun 9.

Keck School of Medicine, University of Southern California (USC), Los Angeles, CA, USA.

As of April 17th, 2020, more than 2,190,010 COVID-19 cases with 147,010 deaths have been recorded worldwide. It has been suggested that a high mortality rate occurs in patients with severe disease and is associated with advanced age and underlying comorbidities, such as malignancies. To the best of our knowledge, no study has been conducted to evaluate chest CT features in patients with malignancy and concomitant COVID-19 infection. Read More

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http://dx.doi.org/10.1016/j.clinimag.2020.06.004DOI Listing

Sleep and development in adolescence in the context of socioeconomic disadvantage.

J Adolesc 2020 Jun 30;83:1-11. Epub 2020 Jun 30.

Auburn University, Auburn, AL, USA.

Introduction: Sleep problems are associated with negative developmental outcomes in youth, and identification of vulnerability and protective factors is needed to explicate for whom and under which conditions adolescents may be most at risk. Towards this end, we examined socio-economic status (SES) as a moderator of associations between multiple sleep parameters and adolescents' socio-emotional adjustment and cognitive functioning.

Methods: Participants were 272 adolescents (M age = 17. Read More

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http://dx.doi.org/10.1016/j.adolescence.2020.06.006DOI Listing
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