239,496 results match your criteria African Journal of Traditional Complementary and Alternative Medicines[Journal]

Real-world burden of systemic lupus erythematosus in the USA: a comparative cohort study from the Medical Expenditure Panel Survey (MEPS) 2016-2018.

Lupus Sci Med 2022 May;9(1)

US Evidence, AstraZeneca Pharmaceuticals LP, Wilmington, Delaware, USA.

Objective: SLE is a chronic, multiorgan, autoimmune disease; however, current prevalence estimates are dated and often from non-generalisable patient populations, and quality of life and patient-reported outcomes in the real-world SLE population are not well-published. The present study used the Medical Expenditure Panel Survey (MEPS), a generalisable US data source encompassing a representative sample of regions/payers, to estimate SLE prevalence and characterise disease burden compared with non-SLE respondents.

Methods: Retrospective population-based survey data weighted to the full US population from MEPS for the calendar years 2016-2018, pooled over the full study period, was used. Read More

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Tuberculosis incidence in patients with chronic kidney disease: a systematic review and meta-analysis.

Int J Infect Dis 2022 May 21. Epub 2022 May 21.

Aklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia.

Objective: To estimate global tuberculosis (TB) incidence in Chronic Kidney Disease (CKD) patients.

Methods: The PRISMA method was followed to perform the study. Electronic and gray literature sources were investigated for studies published between 2000 and 2021. Read More

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Firearm trauma: Race and insurance influence mortality and discharge disposition.

J Trauma Acute Care Surg 2022 Jun 18;92(6):1005-1011. Epub 2022 Jan 18.

From the Department of Surgery (D.C.L., A.P.M., F.W.E., C.J.R., R.M.N.), Hennepin Healthcare; and Clinical and Translational Science Institute (R.L.F.), Biostatistical Design and Analysis Center, University of Minnesota, Minneapolis, Minnesota.

Background: Health insurance and race impact mortality and discharge outcomes in the general trauma population. It remains unclear if disparities exist by race and/or insurance in outcomes following firearm injuries. The purpose of this study was to assess differences in mortality and discharge based on race and insurance status following firearm injuries. Read More

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Predicting 31- to 60-Day Heart Failure Rehospitalization Among Older Women.

Res Gerontol Nurs 2022 May 27:1-13. Epub 2022 May 27.

The current study sought to identify social, hemodynamic, and comorbid risk factors associated with 31-to 60-day heart failure (HF) rehospitalization in African American and Caucasian older (aged >65 years) women. A non-equivalent, case-control, quantitative design study using secondary data analysis of medical records from a local community hospital in the Southeast region of the United States was performed over a 3-year period. Relationships between predictor variables and the outcome variable, 31- to 60-day HF rehospitalization, were explored. Read More

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Effects of treatments on gender differences in patients with localized muscle-invasive bladder cancer.

Int Urol Nephrol 2022 May 24. Epub 2022 May 24.

Department of Urology, Sir Run Run Shaw Hospital, Medicine School of Zhejiang University, 3 Qingchun East Road, Shangcheng District, Hangzhou, 310016, Zhejiang, China.

Purpose: To explore the gender differences in survival under different treatments in localized muscle-invasive bladder cancer (MIBC), and to find clinical strategies to improve the poor prognosis of female with bladder cancer (BC).

Methods: Patients with localized MIBC were collected in the SEER database from 2010 to 2016 to analyze the gender differences in clinical characteristics. Propensity score matching was used to balance the effects of confounding factors. Read More

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Impact of preoperative opioid use on patient-reported outcomes following primary total knee arthroplasty.

Eur J Orthop Surg Traumatol 2022 May 24. Epub 2022 May 24.

Department of Orthopedic Surgery, NYU Langone Health, 301 East 17 th Street , New York, NY, 10003, USA.

Purpose: The previous literature suggests that 25-30% of patients who undergo total knee arthroplasty (TKA) are using opioids prior to their surgery. This study aims to investigate the effect of preoperative opioid use on clinical outcomes and patient-reported outcome measures (PROMs) following TKA.

Methods: We retrospectively reviewed 329 patients who underwent primary TKA from 2019 to 2020, answered the preoperative opioid survey, and had available PROMs. Read More

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Validation of coronavirus-2019 phobia scale using preschool practitioners in urban and rural communities in Nigeria: Implication for educational sociologists.

Medicine (Baltimore) 2022 May 20;101(20):e29209. Epub 2022 May 20.

Department of Educational Foundations, Faculty of Education, University of Nigeria, Nsukka, Nigeria.

Abstract: Coronavirus-2019 (COVID-19) emerged in December 2019, causing significant changes in people's social lives and other human activities. The outbreak halted educational activities throughout the world. The Nigerian experience was unique in that most people were skeptical about the pandemic's existence. Read More

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The oxidized-LDL/LOX-1 axis in tumor endothelial cells enhances metastasis by recruiting neutrophils and cancer cells.

Int J Cancer 2022 May 24. Epub 2022 May 24.

Vascular Biology and Molecular Pathology, Hokkaido University Graduate School of Dental Medicine, Sapporo, Japan.

Epidemiological relationships between cancer and cardiovascular diseases have been reported, but a molecular basis remains unclear. Some proteoglycans that strongly bind low-density-lipoprotein (LDL) are abundant both in atherosclerotic regions and in high metastatic-tumor tissue. LDL retention is crucial for the initiation of atherosclerosis, although its contribution to malignancy of cancer is not known. Read More

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Isoniazid preventive therapy and TB transcriptional signatures in people with HIV.

AIDS 2022 May 24. Epub 2022 May 24.

Department of Medicine, University of Washington, Seattle, WA.

Objectives: To examine the association between isoniazid preventive therapy (IPT) or nontuberculous mycobacteria (NTM) sputum culture positivity and tuberculosis (TB) transcriptional signatures in people with HIV.

Design: Cross-sectional study.

Methods: We enrolled adults living with HIV who were IPT-naive or had completed IPT more than 6 months prior at HIV care clinics in western Kenya. Read More

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Long-term HIV treatment outcomes and associated factors in sub-Saharan Africa: multi-country longitudinal cohort analysis.

AIDS 2022 May 24. Epub 2022 May 24.

Amsterdam Institute for Global Health and Development, and Department of Global Health, Amsterdam UMC, University of Amsterdam.

Objective: In a multicountry prospective cohort of persons with HIV from six countries between 2007 and 2015, we evaluated long-term outcomes of first-line non-nucleoside reverse-transcriptase inhibitor-based antiretroviral therapy (ART), and risk factors for loss-to-follow-up, mortality, virological failure, and incomplete CD4+ T-cell recovery.

Methods: We calculated cumulative incidence of lost-to-follow-up, death, virological failure (VL ≥ 1000 cps/ml) and incomplete CD4+ T-cell recovery (<500 cells/μl) at successive years, using Kaplan-Meier and Cox regression.

Results: Of 2735 participants, 58. Read More

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High mortality among patients hospitalized for drug-resistant tuberculosis with acquired second-line drug resistance and high HIV prevalence.

HIV Med 2022 May 24. Epub 2022 May 24.

Vanderbilt Tuberculosis Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.

Objectives: We compared mortality between HIV-positive and HIV-negative South African adults with drug-resistant tuberculosis (DR-TB) and high incidence of acquired second-line drug resistance.

Methods: We performed a retrospective review of DR-TB patients with serial second-line TB drug susceptibility tests (2008-2015) who were hospitalized at a specialized TB hospital. We used Kaplan-Meier analysis and Cox models to examine associations with mortality. Read More

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An examination of predisposing and enabling factors that predict dental utilization among individuals with serious mental illness in Detroit, Michigan.

Community Dent Oral Epidemiol 2022 May 24. Epub 2022 May 24.

University of Detroit Mercy, Detroit, Michigan, USA.

Objectives: This study evaluated which predisposing and enabling factors prospectively predicted dental utilization over 6 months among people with serious mental illness.

Methods: A sample of individuals with serious mental illness (86.3% African American; 97. Read More

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Race-Discordant School Attendance and Cognitive Function in Later Life.

Res Aging 2022 May 23:1640275221103791. Epub 2022 May 23.

Department of Sociology, 7823Florida State University, Tallahassee, FL, USA.

Early schooling plays an important role in shaping cognitive development. This study explored benefits of cognitive functioning in later life related to attending diverse schools in early life. Specifically, we explored the effects of having attended schools composed primarily of different race peers-race discordant schools (RDS)-among Black and White older adults. Read More

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Shrinking Lung Syndrome in a Young Female: A Rare Pulmonary Manifestation of Systemic Lupus Erythematosus.

Cureus 2022 Apr 20;14(4):e24320. Epub 2022 Apr 20.

Internal Medicine, Henry Ford Health System, Detroit, USA.

Shrinking lung syndrome (SLS) is a rare pulmonary complication of autoimmune conditions. It has been sparsely described in the literature and its pathophysiology remains unclear. SLS is typically reported in patients with a history of systemic lupus erythematosus (SLE) who present with shortness of breath and chest pain associated with breathing. Read More

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Application of DPSIR model to identify the drivers and impacts of land use and land cover changes and climate change on land, water, and livelihoods in the L. Kyoga basin: implications for sustainable management.

Environ Syst Res (Heidelb) 2022 19;11(1):11. Epub 2022 May 19.

African Centre of Excellence for Water Management, Addis Ababa University, P. O. Box 1176, Addis Ababa, Ethiopia.

Land use, land cover, and climate change impacts are current global challenges that are affecting many sectors, like agricultural production, socio-economic development, water quality, and causing land fragmentation. In developing countries like Uganda, rural areas with high populations dependent on agriculture are the most affected. The development of sustainable management measures requires proper identification of drivers and impacts on the environment and livelihoods of the affected communities. Read More

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Seroprevalence and Risk Factors of African Horse Sickness in Three Agroecological Zones of Cameroon.

Vet Med Int 2022 14;2022:2457772. Epub 2022 May 14.

Department of Animal Science, Faculty of Agronomy and Agricultural Sciences, University of Dschang, B.P. 222, Dschang, Cameroon.

African horse sickness (AHS), a highly fatal arbovirosis of equines is endemic in sub-Saharan Africa. However, its epidemiology is poorly known in Cameroon. This study aimed to investigate the prevalence profile and risk factors of African horse sickness in Cameroon. Read More

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The impact of socio-economic indicators on COVID-19: an empirical multivariate analysis of sub-Saharan African countries.

J Soc Econ Dev 2022 May 19:1-18. Epub 2022 May 19.

Communication and Study Skills Unit, University of Botswana, Private Bag UB 0022, Gaborone, Botswana.

The COVID-19 pandemic has triggered an unprecedented social and economic crisis. This study aims at investigating the impact of socio-economic indicators on the levels of COVID-19 (confirmed and death cases) in sub-Saharan Africa. The investigation makes use of the readily accessible public data: we obtain COVID-19 data from Johns Hopkins and socio-economic indicators from the World Bank. Read More

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Predicting the Kidney Graft Survival Using Optimized African Buffalo-Based Artificial Neural Network.

J Healthc Eng 2022 14;2022:6503714. Epub 2022 May 14.

Laboratory of Nano-Smart Materials for Science and Technology (LNSMST), Department of Physics, Faculty of Science, King Khalid University, Abha 61413, Saudi Arabia.

A variety of receptor and donor characteristics influence long-and short-term kidney graft survival. It is critical to predict the effectiveness of kidney transplantation to optimise organ allocation. This would allow patients to choose the best accessible kidney donor and the optimal immunosuppressive medication. Read More

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Intestinal Tuberculosis Presenting with Gastrointestinal Bleeding in Patient on Warfarin Therapy.

Case Rep Gastrointest Med 2022 14;2022:9277789. Epub 2022 May 14.

Aga Khan University Hospital Nairobi, 4th Floor East Tower Block, Third Avenue Parklands, P.O. Box 30270, Nairobi 00100, GPO, Kenya.

Background: Intestinal tuberculosis (ITB) constitutes less than 5% of overall cases of extrapulmonary disease and mostly affects the ileocecal region. The presentation and radiologic findings in enteric tuberculosis can mimic Crohn's disease (CD). . Read More

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Cognitive Limitations Among Middle Eastern and North African Immigrants.

J Aging Health 2022 May 23:8982643221103712. Epub 2022 May 23.

Institute for Social Research, 1259University of Michigan, Ann Arbor, MI, USA.

Objectives: To estimate and compare the prevalence of cognitive limitations among Middle Eastern and North African (MENA) immigrants compared to US- and foreign-born non-Hispanic Whites from Europe (including Russia/former USSR) and examine differences after controlling for risk factors.

Methods: Cross-sectional data using linked 2000-2017 National Health Interview Survey and 2001-2018 Medical Expenditure Panel Survey data (ages >=65 years, = 24,827) were analyzed.

Results: The prevalence of cognitive limitations was 17. Read More

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Acute bilateral ureteropelvic junction obstruction as a rare cause of hypertensive crisis: a case report.

J Med Case Rep 2022 May 23;16(1):220. Epub 2022 May 23.

Department of Medicine, Einstein Medical Center Philadelphia, Philadelphia, PA, USA.

Background: Bilateral ureteropelvic junction obstruction is a common cause of secondary hypertension in the pediatric population, often due to congenital malformation. On the other hand, it is less frequently encountered in the adult population and is usually due to an acquired condition, most commonly by a bilaterally obstructing nephrolithiasis causing hydronephrosis and subsequent hypertension. The aim of this study was to investigate and highlight the underlying mechanisms by which acute bilateral ureteropelvic junction obstruction causes hypertensive crisis and why early detection and prompt treatment are necessary to mitigate the effects of elevated blood pressure on target organs. Read More

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Prevalence of drinking or eating more than usual and associated factors during childhood diarrhea in East Africa: a multilevel analysis of recent demographic and health survey.

BMC Pediatr 2022 May 23;22(1):301. Epub 2022 May 23.

Department of Health Systems and Policy, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Background: Diarrhea is the second most common cause of death in under-five children. Fluid and food replacement during diarrheal episodes have a paramount effect to avert morbidity and mortality. However, there is limited information about feeding practices. Read More

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SARS-CoV-2 cases reported from long-term residential facilities (care homes) in South Africa: a retrospective cohort study.

BMC Public Health 2022 May 24;22(1):1035. Epub 2022 May 24.

Division of Public Health Surveillance and Response, National Institute for Communicable Diseases, Johannesburg, South Africa.

Background: Globally, long-term care facilities (LTCFs) experienced a large burden of deaths during the COVID-19 pandemic. The study aimed to describe the temporal trends as well as the characteristics and risk factors for mortality among residents and staff who tested positive for SARS-CoV-2 in selected LTCFs across South Africa.

Method: We analysed data reported to the DATCOV sentinel surveillance system by 45 LTCFs. Read More

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Survival and predictors of mortality among chronic kidney disease patients on hemodialysis in Amhara region, Ethiopia, 2021.

BMC Nephrol 2022 May 23;23(1):193. Epub 2022 May 23.

Department of Nursing, School of Nursing and Midwifery, College of Medicine and Health Science, Debre Berhan University, PO box 445, Debre Berhan, Ethiopia.

Background: Despite the high economic and mortality burden of chronic kidney disease, studies on survival and predictors of mortality among patients on hemodialysis in Ethiopia especially in the Amhara region are scarce considering their importance to identify some modifiable risk factors for early mortality to improve the patient's prognosis. So, this study was done to fill the identified gaps. The study aimed to assess survival and predictors of mortality among end-stage renal disease patients on hemodialysis in Amhara regional state, Ethiopia, 2020/2021. Read More

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Insecticide resistant Anopheles gambiae have enhanced longevity but reduced reproductive fitness and a longer first gonotrophic cycle.

Sci Rep 2022 May 23;12(1):8646. Epub 2022 May 23.

Department of Medical Microbiology, College of Health Sciences, University of Ghana Medical School, University of Ghana, Accra, Ghana.

Widespread insecticide resistance in African malaria vectors raises concerns over the potential to compromise malaria vector control interventions. Understanding the evolution of resistance mechanisms, and whether the selective disadvantages are large enough to be useful in resistance management or designing suitable control strategies is crucial. This study assessed whether insecticide resistance to pyrethroids has an effect on the gonotrophic cycle and reproductive potential of malaria vector Anopheles gambiae. Read More

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Clinical outcome and incidence of inhibitor development in severe hemophilia patients receiving low-dose prophylaxis: a 3-year follow-up study in Senegal, West Africa.

Hematol Transfus Cell Ther 2022 May 15. Epub 2022 May 15.

Cheikh Anta Diop University, Dakar, Senegal; National Blood Transfusion Center, Dakar, Senegal.

Introduction: In Africa, where access to diagnosis and treatment of hemophilia is the lowest in the world, prophylaxis is rarely used in preference to on-demand treatment. There are limited data of prophylaxis treatment from sub-Saharan Africa. The aim of this study was to evaluate clinical outcomes and inhibitor development in people with hemophilia receiving low-dose prophylaxis (LDP) in a sub-Saharan African setting. Read More

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"Can i donate a kidney?" Common questions and simplified answers to the prospective kidney donor.

J Natl Med Assoc 2022 May 20. Epub 2022 May 20.

Northwestern Medicine, Arkes Family Pavilion Suite 1900, African American Transplant Access Program (AATAP), 676 N Saint Clair, Chicago, IL 60611, United States.

For individuals with end stage kidney disease (ESKD), kidney transplantation is associated with reduced morbidity, mortality, and decreased health care costs. African Americans have higher rates of end stage kidney disease (ESKD) and reduced access to transplantation compared to their White counterparts. One way to improve access to transplantation is by increasing the number of living donors. Read More

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A Scoping Review on Community-Based Programs to Promote Physical Activity in Older Immigrants.

J Aging Phys Act 2022 May 23:1-11. Epub 2022 May 23.

Faculty of Nursing, University of Alberta, Edmonton, AB,Canada.

Older immigrants are at higher risks for inactivity due to cultural, environmental, and social barriers in the postmigration context. Community-based physical activity (PA) programs increase PA in older adults, yet little is known about approaches that specifically target older immigrants. This scoping review explores the literature on community-based programs that increase PA and physical fitness in immigrant older adults and identifies barriers and facilitators to PA program participation in this population. Read More

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Lipoprotein(a) and ethnicities.

Atherosclerosis 2022 May;349:42-52

Section of Cardiovascular Research, Department of Medicine, Baylor College of Medicine, Houston, TX, USA; Health Policy, Quality & Informatics Program, Michael E. DeBakey Veterans Affairs Medical Center Health Services Research and Development Center for Innovations, USA. Electronic address:

The initial studies focusing on lipoprotein(a) [Lp(a)] and its role in atherosclerotic cardiovascular disease were conducted exclusively in Whites. Subsequently, multiple large-scale, independent investigations have established clear race/ethnic differences in plasma Lp(a) concentration and population distribution over the last four decades. Blacks have the highest Lp(a) level of all race/ethnic groups studied followed by South Asians, Whites, Hispanics and East Asians. Read More

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