31,918 results match your criteria Aerospace Basel Switzerland[Journal]


Ultrasound multiple scattering with microbubbles can differentiate between tumor and healthy tissue in vivo.

Phys Med Biol 2019 Apr 17. Epub 2019 Apr 17.

Department of Mechanical and Aerospace Engineering, North Carolina State University, Raleigh, North Carolina, UNITED STATES.

Most solid tumors are characterized by highly dense, isotropic vessel networks. Characterization of such features has shown promise for early cancer diagnosis. Ultrasound diffusion has been used to characterize the micro-architecture of complex media, such as bone and the lungs. Read More

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http://iopscience.iop.org/article/10.1088/1361-6560/ab1a44
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http://dx.doi.org/10.1088/1361-6560/ab1a44DOI Listing
April 2019
1 Read

Electrical stimulation facilitates the angiogenesis of human umbilical vein endothelial cells through MAPK/ERK signaling pathway by stimulating FGF2 secretion.

Am J Physiol Cell Physiol 2019 Apr 17. Epub 2019 Apr 17.

Department of Burns and Plastic Surgery, the Affiliated Hospital of Southwest Medical University, Luzhou 646000, China.

Electrical stimulation (ES) is able to enhance angiogenesis by stimulating fibroblasts. Fibroblast growth factor 2 (FGF2) is an independent angiogenesis inducer. The current study aimed to evaluate the role of ES-induced FGF2 secretion in affecting angiogenesis during wound healing the mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) signaling pathway. Read More

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http://dx.doi.org/10.1152/ajpcell.00474.2018DOI Listing

cGMP manipulation in cardiometabolic disease: chances and challenges.

Curr Opin Cardiol 2019 Apr 15. Epub 2019 Apr 15.

Institute of Pharmacology and Toxicology, University Hospital Bonn, University of Bonn, Bonn, Germany.

Purpose Of Review: Cardiovascular and metabolic diseases are closely linked and commonly occur in the same patients. This review focuses on the cyclic guanosine monophosphate (cGMP) system and its crosstalk between metabolism and the cardiovascular system.

Recent Findings: Recent studies suggest that cGMP, which serves as second messenger for nitric oxide and for natriuretic peptides, improves oxidative metabolism and insulin signaling. Read More

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http://dx.doi.org/10.1097/HCO.0000000000000630DOI Listing

Investigating the Effect of APAP Crystals on Tablet Behavior Manufactured by Direct Compression.

AAPS PharmSciTech 2019 Apr 16;20(5):168. Epub 2019 Apr 16.

Department of Mechanical and Aerospace Engineering, Rutgers University, 98 Brett Road, Piscataway, New Jersey, 08854, USA.

In this work, the effect of API's (Active Pharmaceutical Ingredient) shape and size on tablet characteristics is investigated for high API dose formulation manufactured by direct compression. Three different classes of APAP (acetaminophen) are selected, and tablets are produced in both single and batch processes. After performing and comparing comprehensive series of standard characterization tests including hardness, dissolution, disintegration, and friability on the tablets, the test results show the relation between the quality of APAP tablets and the shape and size of the crystals. Read More

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http://dx.doi.org/10.1208/s12249-019-1369-0DOI Listing

A surface with stress, extensional elasticity, and bending stiffness.

Soft Matter 2019 Apr 17. Epub 2019 Apr 17.

Department of Chemical and Biomolecular Engineering, Lehigh University, Bethlehem, PA 18017, USA. and Department of Bioengineering, Lehigh University, Bethlehem, PA 18017, USA.

We demonstrate that the surface of a commonly used polydimethylsiloxane formulation (PDMS, Sylgard 184) treated by ultraviolet ozonolysis (UVO) has significant surface stress, considerable extensional elasticity (the "Shuttleworth Effect"), and surface bending elasticity. For soft solids, phenomena such as wetting, contact, surface flattening, and stiffening by liquid inclusions are often governed by their surface, which is usually represented by a liquid-like constant surface stress. Whether the surfaces of soft solids can have more complex constitutive response is actively debated. Read More

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http://dx.doi.org/10.1039/c9sm00075eDOI Listing

Water vapor capturing using an array of traveling liquid beads for desalination and water treatment.

Sci Adv 2019 Apr 12;5(4):eaav7662. Epub 2019 Apr 12.

Mechanical and Aerospace Engineering Department, University of California-Los Angeles, Los Angeles, CA 90095, USA.

Growing concern over the scarcity of freshwater motivates the development of compact and economic vapor capture methods for distributed thermal desalination or harvesting of water. We report a study of water vapor condensation on cold liquid beads traveling down a massive array of vertical cotton threads that act as pseudo-superhydrophilic surfaces. These liquid beads form through intrinsic flow instability and offer localized high-curvature surfaces that enhance vapor diffusion toward the liquid surface, a critical rate-limiting step. Read More

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http://advances.sciencemag.org/lookup/doi/10.1126/sciadv.aav
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http://dx.doi.org/10.1126/sciadv.aav7662DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461458PMC
April 2019
1 Read

Homogeneous guiding deposition of sodium through main group II metals toward dendrite-free sodium anodes.

Sci Adv 2019 Apr 12;5(4):eaau6264. Epub 2019 Apr 12.

Key Laboratory of Aerospace Advanced Materials and Performance of Ministry of Education, School of Materials Science and Engineering, Beihang University, Beijing 100191, China.

Metallic sodium is a potential anode material for rechargeable sodium-based batteries because of its high specific capacity and low cost. However, sodium commonly suffers from severe sodium dendrites and infinitely huge volume change, hampering its practical applications. Here, we demonstrate that sodium can be controllably deposited through main group II metals such as Be, Mg, and Ba since they have definite solubility in sodium and thus enable a marked reduction of the nucleation barriers of sodium, guiding the parallel growth of sodium on the metal substrates. Read More

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http://dx.doi.org/10.1126/sciadv.aau6264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461461PMC

Vanadium disulfide flakes with nanolayered titanium disulfide coating as cathode materials in lithium-ion batteries.

Nat Commun 2019 Apr 16;10(1):1764. Epub 2019 Apr 16.

Department of Mechanical, Aerospace and Nuclear Engineering, Rensselaer Polytechnic Institute, 110 8th Street, Troy, NY, 12180, USA.

Unlike the vast majority of transition metal dichalcogenides which are semiconductors, vanadium disulfide is metallic and conductive. This makes it particularly promising as an electrode material in lithium-ion batteries. However, vanadium disulfide exhibits poor stability due to large Peierls distortion during cycling. Read More

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http://dx.doi.org/10.1038/s41467-019-09400-wDOI Listing

Retraction mechanics of Finochietto-style self-retaining thoracic retractors.

Biomed Eng Online 2019 Apr 16;18(1):45. Epub 2019 Apr 16.

Physcient Inc., 112 South Duke St., Suite 4A, Durham, NC, 27701, USA.

Objectives: Analyze the mechanics of Finochietto-style retractors, including the responses of thoracic tissues during thoracotomy, with an emphasis on tissue trauma and means for its reduction.

Methods: Mechanical analyses of the retractor were performed, including analysis of deformation under load and kinematics of the crank mechanism. Thoracotomies in a porcine model were performed in anesthetized animals (7) and fresh cadavers (17) using an instrumented retractor. Read More

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http://dx.doi.org/10.1186/s12938-019-0664-zDOI Listing

Aerodynamic effects of varying solid surface area of bristled wings performing clap and fling.

Bioinspir Biomim 2019 Apr 16. Epub 2019 Apr 16.

School of Mechanical and Aerospace Engineering, Oklahoma State University, Stillwater, Oklahoma, UNITED STATES.

The smallest flying insects with body lengths under 1 mm show a marked preference for wings consisting of a thin membrane with long bristles, and the use of clap and fling kinematics to augment lift at Reynolds numbers (Re) of approximately 10. Bristled wings have been shown to reduce drag forces in clap and fling, but the aerodynamic roles of several bristled wing geometric variables remain unclear. This study examines the effects of varying the ratio of membrane area (<i>A</i><sub>M</sub>) to total wing area (<i>A</i><sub>T</sub>) on aerodynamic forces and flow structures generated during clap and fling at Re on the order of 10. Read More

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http://dx.doi.org/10.1088/1748-3190/ab1a00DOI Listing

Printing in situ tissue sealant with visible-light-crosslinked porous hydrogel.

Biomed Mater 2019 Apr 16. Epub 2019 Apr 16.

Department of Mechanical and Aerospace Engineering, Monash University, Wellington Road, Clayton, Victoria 3800, Clayton, Victoria, 3800, AUSTRALIA.

To reflect the rapidly growing interest in producing tissue sealants using various chemical/physical processes, we report an approach using visible light to control the crosslinking of 3D printable hydrogels as in situ tissue sealant. Gelatin-hydroxyphenylpropionic acid conjugate (Gtn-HPA) is shown to crosslink effectively within 30 seconds under visible light in the presence of [RuII(bpy)3]2+ and sodium persulphate, which is sufficiently rapid for surgery use. Porous structure can be also introduced by including carboxylmethyl cellulose-tyramine (CMC-Tyr) as a precursor. Read More

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http://dx.doi.org/10.1088/1748-605X/ab19feDOI Listing

Bimetallic Fe/Al system: An all-in-one solid-phase Fenton reagent for generation of hydroxyl radicals under oxic conditions.

Sci Total Environ 2019 Apr 10;673:480-488. Epub 2019 Apr 10.

Department of Civil and Environmental Engineering, National University of Kaohsiung, 811 Kaohsiung, Taiwan.

In the classic Fenton reaction, both HO and ferrous ion (Fe(II)) are required under a narrow low pH range to produce hydroxyl radicals (OH). The modified Fenton processes including heterogeneous Fenton-like reaction, photo-Fenton reaction and electro-Fenton reaction developed to overcome the drawbacks of the homogeneous Fenton reaction have recently received increasing attention. However, all the modifications of the classic Fenton reaction cannot be assembled into one system and require external supply of reagents or energy. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2019.04.116DOI Listing
April 2019
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Self-Healing, Adhesive, and Highly Stretchable Ionogel as a Strain Sensor for Extremely Large Deformation.

Small 2019 Apr 16:e1804651. Epub 2019 Apr 16.

Kavli Institute for Bionano Science and Technology, John A. Paulson School of Engineering and Applied Science, Harvard University, Cambridge, MA, 02138, USA.

Fabricating a strain sensor that can detect large deformation over a curved object with a high sensitivity is crucial in wearable electronics, human/machine interfaces, and soft robotics. Herein, an ionogel nanocomposite is presented for this purpose. Tuning the composition of the ionogel nanocomposites allows the attainment of the best features, such as excellent self-healing (>95% healing efficiency), strong adhesion (347. Read More

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http://dx.doi.org/10.1002/smll.201804651DOI Listing
April 2019
1 Read

Cerebellar folding is initiated by mechanical constraints on a fluid-like layer without a cellular pre-pattern.

Elife 2019 Apr 16;8. Epub 2019 Apr 16.

Developmental Biology Program, Sloan Kettering Institute, New York, United States.

Models based in differential expansion of elastic material, axonal constraints, directed growth, or multi-phasic combinations have been proposed to explain brain folding. However, the cellular and physical processes present during folding have not been defined. We used the murine cerebellum to challenge folding models with in vivo data. Read More

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http://dx.doi.org/10.7554/eLife.45019DOI Listing

Deconvolution in Intravascular Ultrasound to Improve Lateral Resolution.

Ultrason Imaging 2019 Apr 16:161734619838456. Epub 2019 Apr 16.

1 Department of Precision Machinery & Precision Instrumentation, University of Science and Technology of China, Hefei, China.

Intravascular ultrasound (IVUS) is an important diagnostic method for coronary disease. The lateral and axial resolutions of IVUS systems under study are typically ~120 and ~30 µm, respectively. The lateral resolution has a lower quality than the axial one and is restricted by the aperture size of transducers. Read More

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http://dx.doi.org/10.1177/0161734619838456DOI Listing

Development and effectiveness of virtual interactive working memory training for older people with mild cognitive impairment: a single-blind randomised controlled trial.

Age Ageing 2019 Apr 15. Epub 2019 Apr 15.

School of Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan.

Background: memory training is a potential intervention for retaining memory and reducing dementia risk in older adults with mild cognitive impairment (MCI).

Objective: this study examined the effect of virtual interactive working memory training (VIMT) in older adults with MCI.

Design: single-blind, two-arm parallel-group, randomised controlled design. Read More

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http://dx.doi.org/10.1093/ageing/afz029DOI Listing

Inter-Session Reliability of the Tennis Serve and Influence of the Laboratory Context.

J Hum Kinet 2019 Mar 27;66:57-67. Epub 2019 Mar 27.

Laboratory of Human Motion Analysis, University of Liège, Liège, Belgium.

To meet the demand of a player's entourage (e.g., coaches and medical staff), it is important for the biomechanics specialist to perform repeatable measures. Read More

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http://content.sciendo.com/view/journals/hukin/66/1/article-
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http://dx.doi.org/10.2478/hukin-2018-0064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458585PMC
March 2019
1 Read

Atomic and electronic reconstruction at the van der Waals interface in twisted bilayer graphene.

Nat Mater 2019 Apr 15. Epub 2019 Apr 15.

Department of Physics, Harvard University, Cambridge, MA, USA.

Control of the interlayer twist angle in two-dimensional van der Waals (vdW) heterostructures enables one to engineer a quasiperiodic moiré superlattice of tunable length scale. In twisted bilayer graphene, the simple moiré superlattice band description suggests that the electronic bandwidth can be tuned to be comparable to the vdW interlayer interaction at a 'magic angle', exhibiting strongly correlated behaviour. However, the vdW interlayer interaction can also cause significant structural reconstruction at the interface by favouring interlayer commensurability, which competes with the intralayer lattice distortion. Read More

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http://dx.doi.org/10.1038/s41563-019-0346-zDOI Listing

Water walking as a new mode of free surface skipping.

Sci Rep 2019 Apr 15;9(1):6042. Epub 2019 Apr 15.

Utah State University, Department of Mechanical & Aerospace Engineering, Logan, UT, 84321, USA.

Deformable elastomeric spheres are evaluated experimentally as they skip multiple times over a lake surface. Some spheres are embedded with small inertial measurement units to measure the acceleration experienced during water surface impact. A model for multiple impact events shows good agreement between measured acceleration, number of skipping events and distanced traveled. Read More

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http://dx.doi.org/10.1038/s41598-019-42453-xDOI Listing

Improved Mechanical and Moisture-Resistant Properties of Woven Hybrid Epoxy Composites by Graphene Nanoplatelets (GNP).

Materials (Basel) 2019 Apr 16;12(8). Epub 2019 Apr 16.

Science and Technology Research Institute for Defence, Kajang 43000, Selangor, Malaysia.

This research investigated the effect of adding different wt.% (0, 0.25, 0. Read More

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http://dx.doi.org/10.3390/ma12081249DOI Listing

Investigation on the dynamic characteristics and control accuracy of a novel proportional directional valve with independently controlled pilot stage.

ISA Trans 2019 Mar 27. Epub 2019 Mar 27.

The Shanghai Aerospace Control Technology Institute, China Aerospace Science and Technology Corporation, No.1555 Zhongchun Road, Shanghai, 201109, China. Electronic address:

The pilot operated directional valves are widely used in hydraulic systems. For the purpose to improve the dynamic characteristics and control accuracy of the traditional valve, this paper proposes a novel pilot valve that employs two independent valve spools instead of the traditional port coupled valve spool. Due to the new structure, the influence of deadzone and damping on the performance of the valve is lightened; the dynamic characteristics and control accuracy of the valve are improved. Read More

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http://dx.doi.org/10.1016/j.isatra.2019.03.023DOI Listing

The Instrument Design of the DLR Earth Sensing Imaging Spectrometer (DESIS).

Sensors (Basel) 2019 Apr 4;19(7). Epub 2019 Apr 4.

Institute of Optical Sensor Systems, DLR, Rutherfordstraße 2, 12489 Berlin, Germany.

Whether for identification and characterization of materials or for monitoring of the environment, space-based hyperspectral instruments are very useful. Hyperspectral instruments measure several dozens up to hundreds of spectral bands. These data help to reconstruct the spectral properties like reflectance or emission of Earth surface or the absorption of the atmosphere, and to identify constituents on land, water, and in the atmosphere. Read More

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https://www.mdpi.com/1424-8220/19/7/1622
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http://dx.doi.org/10.3390/s19071622DOI Listing
April 2019
2 Reads

Dust Aerosol Detection by the Modified CO₂ Slicing Method.

Sensors (Basel) 2019 Apr 4;19(7). Epub 2019 Apr 4.

Japan Aerospace Exploration Agency, Tsukuba 305-8505, Japan.

Dust aerosols, which have diverse and strong influences on the environment, must be monitored. Satellite data are effective for monitoring atmospheric conditions globally. In this work, the modified CO₂ slicing method, a cloud detection technique using thermal infrared data from space, was applied to GOSAT data to detect the dust aerosol layer height. Read More

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http://dx.doi.org/10.3390/s19071615DOI Listing

Relationship between the Intake of n-3 Polyunsaturated Fatty Acids and Depressive Symptoms in Elderly Japanese People: Differences According to Sex and Weight Status.

Nutrients 2019 Apr 3;11(4). Epub 2019 Apr 3.

Department of Environmental and Preventive Medicine, Graduate School of Medical Science, Kanazawa University, 13-1 Takaramachi, Kanazawa, Ishikawa 920-8640, Japan.

n-3 polyunsaturated fatty acids (PUFAs) have been shown to have preventive effects against depression. In this study, we aimed to investigate the associations between the intake of n-3 PUFAs and depression among people according to sex and weight status. We utilized cross-sectional data from the Shika study in Japan. Read More

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http://dx.doi.org/10.3390/nu11040775DOI Listing

A Method for Detecting Atmospheric Lagrangian Coherent Structures Using a Single Fixed-Wing Unmanned Aircraft System.

Sensors (Basel) 2019 Apr 3;19(7). Epub 2019 Apr 3.

Engineering Mechanics Program, Virginia Tech, Blacksburg, VA 24061, USA.

The transport of material through the atmosphere is an issue with wide ranging implications for fields as diverse as agriculture, aviation, and human health. Due to the unsteady nature of the atmosphere, predicting how material will be transported via the Earth's wind field is challenging. Lagrangian diagnostics, such as Lagrangian coherent structures (LCSs), have been used to discover the most significant regions of material collection or dispersion. Read More

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http://dx.doi.org/10.3390/s19071607DOI Listing

Shape Memory Epoxy Polymer (SMEP) Composite Mechanical Properties Enhanced by Introducing Graphene Oxide (GO) into the Matrix.

Materials (Basel) 2019 Apr 3;12(7). Epub 2019 Apr 3.

College of Aerospace and Civil Engineering, Harbin Engineering University, Harbin 150001, China.

Shape memory epoxy polymer (SMEP) composite specimens with different graphene oxide (GO) contents were manufactured to study the effects of GO mass fractions on epoxy polymer composites. While ensuring the shape memory effect of SMEP, the addition of GO also remarkably strengthened the mechanical performance of the polymers. Analyses of the epoxy polymer composites' thermal, mechanical, and shape memory performance were conducted through carrying out dynamic mechanical analysis (DMA), thermogravimetric analysis (TGA), and static tensile, three-point bending, impact, and shape memory tests. Read More

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https://www.mdpi.com/1996-1944/12/7/1107
Publisher Site
http://dx.doi.org/10.3390/ma12071107DOI Listing
April 2019
1 Read

Positioning Information Privacy in Intelligent Transportation Systems: An Overview and Future Perspective.

Sensors (Basel) 2019 Apr 3;19(7). Epub 2019 Apr 3.

Tampere University, 33720 Tampere, Finland.

Today, the Intelligent Transportation Systems (ITS) are already in deep integration phase all over the world. One of the most significant enablers for ITS are vehicle positioning and tracking techniques. Worldwide integration of ITS employing Dedicated Short Range Communications (DSRC) and European standard for vehicular communication, known as ETSI ITS-G5, brings a variety of options to improve the positioning in areas where GPS connectivity is lacking precision. Read More

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http://dx.doi.org/10.3390/s19071603DOI Listing

Role of Polymeric Coating on Metallic Foams to Control the Aeroacoustic Noise Reduction of Airfoils with Permeable Trailing Edges.

Materials (Basel) 2019 Apr 2;12(7). Epub 2019 Apr 2.

Novel Aerospace Materials group, Faculty of Aerospace Engineering, Delft University of Technology (TU Delft), Kluyverweg 1, 2629 HS Delft, The Netherlands.

Studies on porous trailing edges, manufactured with open-cell Ni-Cr-Al foams with sub-millimeter pore sizes, have shown encouraging results for the mitigation of turbulent boundary-layer trailing-edge noise. However, the achieved noise mitigation is typically dependent upon the pore geometry, which is fixed after manufacturing. In this study, a step to control the aeroacoustics effect of such porous trailing edges is taken, by applying a polymeric coating onto the internal foam structure. Read More

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https://www.mdpi.com/1996-1944/12/7/1087
Publisher Site
http://dx.doi.org/10.3390/ma12071087DOI Listing
April 2019
1 Read

A Computational Study of Extinguishment and Enhancement of Propane Cup-Burner Flames by Halon and Alternative Agents.

Fire Saf J 2017 ;91

National Institute of Standard and Technology, 100 Bureau Drive Gaithersburg, MD 20899, USA.

Computations of cup-burner flames in normal gravity have been performed using propane as the fuel to reveal the combustion inhibition and enhancement by the CFBr (halon 1301) and potential alternative fire-extinguishing agents (CHF, CHFCl, and CHFBr). The time-dependent, two-dimensional numerical code used includes a detailed kinetic model (up to 241 species and 3918 reactions), diffusive transport, and a gray-gas radiation model. The peak reactivity spot (i. Read More

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http://dx.doi.org/10.1016/j.firesaf.2017.04.010DOI Listing
January 2017

Bubble-Point Measurements and Modeling of Binary Mixtures of Linear Siloxanes.

J Chem Eng Data 2018 ;63

Department of Aerospace Science & Technology, Politecnico di Milano, Via La Masa 35, 20156 Milano, Italy.

The bubble-point pressures of three binary mixtures of linear siloxanes have been measured. The binary mixtures consist of hexamethyldisiloxane (MM) which is mixed with either octamethyltrisiloxane (MDM), decamethyltetrasiloxane (MDM), and dodecamethylpentasiloxane (MDM). For each mixture, three compositions were measured where MM was present in approximately 25 mol%, 50 mol%, and 75 mol%. Read More

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http://pubs.acs.org/doi/10.1021/acs.jced.8b00200
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http://dx.doi.org/10.1021/acs.jced.8b00200DOI Listing
January 2018
1 Read

A six-degree-of-freedom robotic motion system for quality assurance of real-time image-guided radiotherapy.

Phys Med Biol 2019 Apr 15. Epub 2019 Apr 15.

ACRF Image X Institute, The University of Sydney Central Clinical School, University of Sydney, Sydney, New South Wales, AUSTRALIA.

In this study we develop and characterise a six degree-of-freedom (6DoF) robotic motion system for quality assurance of real-time image-guided radiotherapy techniques. The system consists of a commercially available robotic arm, an acrylic phantom with embedded Calypso markers, a custom base plate to mount the robot to the treatment couch, and control software implementing the appropriate sequence of transformations to reproduce measured tumour motion traces. The robotic motion system was evaluated in terms of the set-up and motion trace repeatability, static localization accuracy and dynamic localization accuracy. Read More

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http://dx.doi.org/10.1088/1361-6560/ab1935DOI Listing

Design of a bio-inspired composite using probabilistic fracture mechanics.

J Mech Behav Biomed Mater 2019 Apr 7;95:96-102. Epub 2019 Apr 7.

Department of Aerospace Engineering, Indian Institute of Space Science and Technology, Thiruvananthapuram, Kerala, India.

Artificial composites inspired from biological materials such as nacre and bone has a staggered structure of hard inclusions surrounded by a soft interface. These composites possess an excellent combination of strength, toughness and stiffness. These properties depends on a critical value of overlap ratio of inclusions, and hence is one of major parameters in the design of bio-inspired composites. Read More

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http://dx.doi.org/10.1016/j.jmbbm.2019.04.001DOI Listing
April 2019
2 Reads

Fluid release pressure for nanochannels: the Young-Laplace equation using the effective contact angle.

Nanoscale 2019 Apr 15. Epub 2019 Apr 15.

Jiangsu Key Laboratory for Design & Manufacture of Micro/Nano Biomedical Instruments and School of Mechanical Engineering, Southeast University, Nanjing 210096, P.R. China.

Releasing fluids from nanochannels is quite challenging, yet crucial for the application of nanofluidic systems, e.g. drug delivery and nanoprinting. Read More

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http://dx.doi.org/10.1039/c8nr08987fDOI Listing
April 2019
1 Read

Searching for Atmospheric Bioindicators in Planets around the Two Nearby Stars, Proxima Centauri and Epsilon Eridani-Test Cases for Retrieval of Atmospheric Gases with Infrared Spectroscopy.

Astrobiology 2019 Apr 13. Epub 2019 Apr 13.

7 Department of Earth System Science, Tsinghua University, Beijing, China.

We tested the ability of thermal infrared spectroscopy to retrieve assumed atmospheric compositions for different types of planets orbiting Proxima Centauri and Epsilon Eridani. Six cases are considered, covering a range of atmospheric compositions and some diversity in the bulk composition (rocky, water ocean, hydrogen rich) and the spectral type of the parent star (M and K stars). For some cases, we applied coupled climate chemistry, or climate-only calculations; for other cases, we assumed the atmospheric composition, ground temperature, and surface reflectivity. Read More

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http://dx.doi.org/10.1089/ast.2018.1938DOI Listing

Efficient proximal resource allocation strategies predict distal team performance: Evidence from the National Hockey League.

J Appl Psychol 2019 Apr 15. Epub 2019 Apr 15.

Naval Aerospace Medical Institute.

To achieve long-term goals, individuals, teams, and organizations must engage in numerous short-term performance episodes. This creates a trade-off between proximal and distal performance. On the one hand, allocating resources toward an episode typically facilitates performance in that episode, thereby to distal success. Read More

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http://dx.doi.org/10.1037/apl0000407DOI Listing

Automated chemical identification and library building using dispersion plots for differential mobility spectrometry.

Anal Methods 2018 Sep 14;10(35):4339-4349. Epub 2018 Aug 14.

Mechanical and Aerospace Engineering, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA.

Differential mobility spectrometry (DMS) based detectors require rapid data analysis capabilities, embedded into the devices to achieve the optimum detection capabiites as portable trace chemical detectors. Automated algorithm-based DMS dispersion plot data analysis method was applied for the first time to pre-process and separate 3-dimentional (3-D) DMS dispersion data. We previously demonstrated our AnalyzeIMS (AIMS) software was capable of analyzing complex gas chromatography differential mobility spectrometry (GC-DMS) data sets. Read More

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http://dx.doi.org/10.1039/C8AY00846ADOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457679PMC
September 2018
1 Read

An EEG/EMG/EOG-Based Multimodal Human-Machine Interface to Real-Time Control of a Soft Robot Hand.

Front Neurorobot 2019 29;13. Epub 2019 Mar 29.

Key Laboratory of Education Ministry for Modern Design and Rotor-Bearing System, School of Mechanical Engineering, Xi'an Jiaotong University, Xi'an, China.

Brain-computer interface (BCI) technology shows potential for application to motor rehabilitation therapies that use neural plasticity to restore motor function and improve quality of life of stroke survivors. However, it is often difficult for BCI systems to provide the variety of control commands necessary for multi-task real-time control of soft robot naturally. In this study, a novel multimodal human-machine interface system (mHMI) is developed using combinations of electrooculography (EOG), electroencephalography (EEG), and electromyogram (EMG) to generate numerous control instructions. Read More

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https://www.frontiersin.org/article/10.3389/fnbot.2019.00007
Publisher Site
http://dx.doi.org/10.3389/fnbot.2019.00007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449448PMC
March 2019
2 Reads

Loss of Sirtuin 1 Alters the Secretome of Breast Cancer Cells by Impairing Lysosomal Integrity.

Dev Cell 2019 Apr 1. Epub 2019 Apr 1.

Department of Molecular Medicine, Cornell University, Ithaca, NY 14853, USA.

The NAD-dependent deacetylase Sirtuin 1 (SIRT1) is down-regulated in triple-negative breast cancer. To determine the mechanistic basis by which reduced SIRT1 expression influences processes related to certain aggressive cancers, we examined the consequences of depleting breast cancer cells of SIRT1. We discovered that reducing SIRT1 levels decreased the expression of one particular subunit of the vacuolar-type H+ ATPase (V-ATPase), which is responsible for proper lysosomal acidification and protein degradation. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S15345807193018
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http://dx.doi.org/10.1016/j.devcel.2019.03.011DOI Listing
April 2019
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Subtyping of influenza A H1N1 virus using a label-free electrochemical biosensor based on the DNA aptamer targeting the stem region of HA protein.

Anal Chim Acta 2019 Aug 9;1064:94-103. Epub 2019 Mar 9.

Department of Biomedical Engineering, Ulsan National Institute of Science and Technology (UNIST), Ulsan, 44919, Republic of Korea; School of Mechanical, Aerospace and Nuclear Engineering, UNIST, Ulsan, 44919, Republic of Korea. Electronic address:

Rapid subtyping of influenza viruses in clinical laboratories has been increasingly important because three subtypes (seasonal H1N1, H3N2, and 2009 H1N1) of influenza A virus currently disseminated in humans have variable susceptibilities to antiviral drug. Herein, we present DNA aptamers for selective detection of influenza A H1N1 (seasonal and 2009 pandemic H1N1) viruses by targeting recombinant influenza A mini-hemagglutinin (mini-HA) protein (the stable stem region of HA) and whole H1N1 viruses. The dissociation constants (K) of aptamer candidates V46 and V57 were 19. Read More

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http://dx.doi.org/10.1016/j.aca.2019.03.005DOI Listing

Effects of dance intervention on global cognition, executive function and memory of older adults: a meta-analysis and systematic review.

Aging Clin Exp Res 2019 Apr 13. Epub 2019 Apr 13.

School of Nursing, Jilin University, 965 XinJiang Road, Changchun, 130021, China.

Objective: To summarize and assess the effects of dance intervention on global cognition, executive function and memory in older adults.

Methods: We searched the databases PubMed, Web of Science, Cochrane Library, EMBASE, Clinical Trials.Gov and four Chinese databases (CNKI, CBM, Wan Fang Data and VIP) to identify articles written in English or Chinese and published until April 2018. Read More

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http://dx.doi.org/10.1007/s40520-019-01159-wDOI Listing

A simple numerical approach for reconstructing the atomic stresses at grain boundaries from quantum-mechanical calculations.

J Chem Phys 2019 Apr;150(14):144702

Department of Aerospace Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.

The atomistic stress state at a metal grain boundary is an intrinsic attribute which affects many physical and mechanical properties of the metal. While the virial stress is an accepted measure of the atomistic stress in molecular dynamics simulations, an equivalent definition is not well-established for quantum-mechanical density functional theory (DFT) calculations. Here, we introduce a numerical technique, termed the sequential atom removal (SAR) approach, to reconstruct the atomic stresses near a symmetrical-tilt Σ5(310)[001] Cu grain boundary. Read More

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http://dx.doi.org/10.1063/1.5085061DOI Listing

Molecular dynamics simulations of nano-confined methanol and methanol-water mixtures between infinite graphite plates: Structure and dynamics.

J Chem Phys 2019 Apr;150(14):144510

Department of Aerospace Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA.

Molecular dynamics simulations are used to investigate microscopic structures and dynamics of methanol and methanol-water binary mixture films confined between hydrophobic infinite parallel graphite plate slits with widths, H, in the range of 7-20 Å at 300 K. The initial geometric densities of the liquids were chosen to be the same as bulk methanol at the same temperature. For the two narrowest slit widths, two smaller initial densities were also considered. Read More

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http://dx.doi.org/10.1063/1.5088030DOI Listing

Impact of strut thickness and number of crown and connectors on clinical outcomes on patients treated with second-generation drug eluting stent.

Catheter Cardiovasc Interv 2019 Apr 13. Epub 2019 Apr 13.

Division of Cardiology, Città Della Salute e della Scienza Hospital, Turin, Italy.

Introduction: In new generation drug eluting stents (DESs) era, the impact of stent geometry on freedom from recurrent events has been poorly explored. Impact of struts thickness and the number of crowns and connectors on clinical outcomes were evaluated in the present study.

Methods: Randomized controlled trials comparing last generation DESs were selected. Read More

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http://dx.doi.org/10.1002/ccd.28228DOI Listing

Tricuspid valve leaflet strains in the beating ovine heart.

Biomech Model Mechanobiol 2019 Apr 12. Epub 2019 Apr 12.

Department of Biomedical Engineering, University of Texas at Austin, 2501 Speedway, Room 7.620, Austin, TX, 78712, USA.

The tricuspid leaflets coapt during systole to facilitate proper valve function and, thus, ensure efficient transport of deoxygenated blood to the lungs. Between their open state and closed state, the leaflets undergo large deformations. Quantification of these deformations is important for our basic scientific understanding of tricuspid valve function and for diagnostic or prognostic purposes. Read More

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http://dx.doi.org/10.1007/s10237-019-01148-yDOI Listing

Flexible electrical aptasensor using dielectrophoretic assembly of graphene oxide and its subsequent reduction for cardiac biomarker detection.

Sci Rep 2019 Apr 12;9(1):5970. Epub 2019 Apr 12.

School of Mechanical, Aerospace and Nuclear Engineering, UNIST, Ulsan, 44919, South Korea.

Cardiac troponin T (cTnT) is considered a clinical standard for its high specificity and sensitivity when diagnosing acute myocardial infarction; however, most studies on the electrical sensors of cardiac troponin biomarkers have focused on cTnI rather than cTnT. This study presents label-free, low-cost, transparent, and flexible aptamer-based immunosensors for the electrical detection of cTnT using reduced graphene oxide (rGO) sheets. GO was first deposited by AC dielectrophoresis between two predefined source and drain electrodes on a 3-aminopropyltriethoxylsilane-modified polyethylene terephthalate substrate. Read More

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http://www.nature.com/articles/s41598-019-42506-1
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http://dx.doi.org/10.1038/s41598-019-42506-1DOI Listing
April 2019
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Mechanical Behavior of Undoped n-Type GaAs under the Indentation of Berkovich and Flat-Tip Indenters.

Materials (Basel) 2019 Apr 11;12(7). Epub 2019 Apr 11.

School of Mechanical and Aerospace Engineering, Jilin University, 5988 RenMin Street, Changchun 130025, China.

In this research, the mechanical behavior of undoped n-type GaAs was investigated by nanoindentation experiments using two types of indenters-Berkovich and flat-tip-with force applied up to 1000 mN. From the measured force-depth curves, an obvious pop-in phenomenon occurred at force of 150 mN with the flat-tip indenter representing elastic-plastic transition. The Young's modulus and hardness of GaAs were calculated to be 60-115 GPa and 6-10 GPa, respectively, under Berkovich indenter. Read More

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http://dx.doi.org/10.3390/ma12071192DOI Listing

Process Fingerprint in Micro-EDM Drilling.

Micromachines (Basel) 2019 Apr 11;10(4). Epub 2019 Apr 11.

Department of Mechanical Engineering, KU Leuven, Member Flanders Make, 3001 Leuven, Belgium.

The micro electrical discharge machining (micro-EDM) process is extensively used in aerospace, automotive, and biomedical industries for drilling small holes in difficult-to-machine materials. However, due to the complexity of the electrical discharge phenomena, optimization of the processing parameters and quality control are time-consuming operations. In order to shorten these operations, this study investigates the applicability of a process fingerprint approach in micro-EDM drilling. Read More

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https://www.mdpi.com/2072-666X/10/4/240
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http://dx.doi.org/10.3390/mi10040240DOI Listing
April 2019
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Vibration-Based In-Situ Detection and Quantification of Delamination in Composite Plates.

Sensors (Basel) 2019 Apr 11;19(7). Epub 2019 Apr 11.

Department of Mechanical Engineering, University of South Carolina, 300 Main Street, Columbia, SC 29208, USA.

This paper presents a new methodology for detecting and quantifying delamination in composite plates based on the high-frequency local vibration under the excitation of piezoelectric wafer active sensors. Finite-element-method-based numerical simulations and experimental measurements were performed to quantify the size, shape, and depth of the delaminations. Two composite plates with purpose-built delaminations of different sizes and depths were analyzed. Read More

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https://www.mdpi.com/1424-8220/19/7/1734
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http://dx.doi.org/10.3390/s19071734DOI Listing
April 2019
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On the Thickness Quantification of Composite Materials by Using Lock-In Thermography.

Authors:
Davide Palumbo

Materials (Basel) 2019 Apr 11;12(7). Epub 2019 Apr 11.

Politecnico di Bari, Viale Japigia, 182, 70126 Bari, Italy.

Many structural components made of composite materials need an accurate thickness control during fabrication and/or maintenance. In this regard, various non-destructive techniques can be used for the online measuring of thickness of large components such as wings and fuselage in the aerospace industry. In this work, the capabilities of lock-in thermography technique in thickness measurement of glass fiber reinforced plastic material were investigated and a correct procedure has been proposed to ensure the best measurement accuracy. Read More

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http://dx.doi.org/10.3390/ma12071185DOI Listing