847 results match your criteria Advances in virus research[Journal]


From foes to friends: Viral infections expand the limits of host phenotypic plasticity.

Adv Virus Res 2020 27;106:85-121. Epub 2020 Jan 27.

Instituto de Biología Integrativa de Sistemas, CSIC-Universitat de València, Valencia, Spain; The Santa Fe Institute, Santa Fe, NM, United States. Electronic address:

Phenotypic plasticity enables organisms to survive in the face of unpredictable environmental stress. Intimately related to the notion of phenotypic plasticity is the concept of the reaction norm that places phenotypic plasticity in the context of a genotype-specific response to environmental gradients. Whether reaction norms themselves evolve and which factors might affect their shape has been the object of intense debates among evolutionary biologists along the years. Read More

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http://dx.doi.org/10.1016/bs.aivir.2020.01.003DOI Listing
January 2020

Structural and cellular biology of adeno-associated virus attachment and entry.

Adv Virus Res 2020 13;106:39-84. Epub 2020 Feb 13.

Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, United States. Electronic address:

Adeno-associated virus (AAV) is a nonenveloped, ssDNA virus in the parvovirus family, which has become one of the leading candidate vectors for human gene therapy. AAV has been studied extensively to identify host cellular factors involved in infection, as well as to identify capsid variants that confer clinically favorable transduction profiles ex vivo and in vivo. Recent advances in technology have allowed for direct genetic approaches to be used to more comprehensively characterize host factors required for AAV infection and allowed for identification of a critical multi-serotype receptor, adeno-associated virus receptor (AAVR). Read More

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http://dx.doi.org/10.1016/bs.aivir.2020.01.002DOI Listing
February 2020

Implications of mixed viral infections on plant disease ecology and evolution.

Adv Virus Res 2020 13;106:145-169. Epub 2020 Mar 13.

Centro de Edafología y Biología Aplicada del Segura-Consejo Superior de investigaciones Científicas (CEBAS-CSIC), Dpto Biología del Estrés y Patología Vegetal, Murcia, Spain. Electronic address:

Mixed viral infections occur more commonly than would be expected by chance in nature. Virus-virus interactions may affect viral traits and leave a genetic signature in the population, and thus influence the prevalence and emergence of viral diseases. Understanding about how the interactions between viruses within a host shape the evolutionary dynamics of the viral populations is needed for viral disease prevention and management. Read More

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http://dx.doi.org/10.1016/bs.aivir.2020.02.001DOI Listing

Exploration of the interactions between mycoviruses and Fusarium graminearum.

Adv Virus Res 2020 5;106:123-144. Epub 2020 Feb 5.

Plant Genomics and Breeding Institute, Seoul National University, Seoul, Republic of Korea; Department of Agricultural Biotechnology, Seoul National University, Seoul, Republic of Korea; Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea. Electronic address:

In this review, we discuss recent studies of the interaction between Fusarium graminearum viruses (FgVs) and the fungal host, Fusarium graminearum. Comprehensive transcriptome and proteome analyses have shown changes in the expression of host genes in response to infection by diverse FgVs. Using omics data and reverse genetics, researchers have determined the effects of some fungal host proteins (including FgHex1, FgHal2, FgSwi6, and vr1) on virus accumulation, virus transmission, and host symptom development. Read More

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http://dx.doi.org/10.1016/bs.aivir.2020.01.004DOI Listing
February 2020

Influenza A virus uncoating.

Authors:
Yohei Yamauchi

Adv Virus Res 2020 13;106:1-38. Epub 2020 Feb 13.

School of Cellular & Molecular Medicine, University of Bristol, Bristol, United Kingdom. Electronic address:

Influenza A virus (IAV) is an enveloped virus of the Orthomyxoviridae with a negative-sense single-stranded RNA genome. During virus cell entry, viral and cellular cues are delivered in a stepwise manner within two distinct cellular compartments-the endosomes and the cytosol. Endosome maturation primes the viral core for uncoating by cytosolic host proteins and host-mediated virus disaggregation is essential for genome import and replication in the nucleus. Read More

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http://dx.doi.org/10.1016/bs.aivir.2020.01.001DOI Listing
February 2020

Preface.

Authors:
Félix A Rey

Adv Virus Res 2019;105:xi-xiii

Structural Virology Unit Virology Department and CNRS UMR3569 Institut Pasteur, Paris, France.

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http://dx.doi.org/10.1016/S0065-3527(19)30051-XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7131067PMC
December 2019

Structural insights into coronavirus entry.

Adv Virus Res 2019 22;105:93-116. Epub 2019 Aug 22.

Department of Biochemistry, University of Washington, Seattle, WA, United States. Electronic address:

Coronaviruses (CoVs) have caused outbreaks of deadly pneumonia in humans since the beginning of the 21st century. The severe acute respiratory syndrome coronavirus (SARS-CoV) emerged in 2002 and was responsible for an epidemic that spread to five continents with a fatality rate of 10% before being contained in 2003 (with additional cases reported in 2004). The Middle-East respiratory syndrome coronavirus (MERS-CoV) emerged in the Arabian Peninsula in 2012 and has caused recurrent outbreaks in humans with a fatality rate of 35%. Read More

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http://dx.doi.org/10.1016/bs.aivir.2019.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112261PMC
December 2019
1 Read

CryoEM reconstruction approaches to resolve asymmetric features.

Adv Virus Res 2019 ;105:73-91

Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA, United States; Department of Medicine, College of Medicine, The Pennsylvania State University, Hershey, PA, United States; Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA, United States. Electronic address:

Although icosahedral viruses have highly symmetrical capsid features, asymmetric structural elements are also present since the genome and minor structural proteins are usually incorporated without adhering to icosahedral symmetry. Besides this inherent asymmetry, interactions with the host during the virus life cycle are also asymmetric. However, until recently it was impossible to resolve high resolution asymmetric features during single-particle cryoEM image processing. Read More

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http://dx.doi.org/10.1016/bs.aivir.2019.07.007DOI Listing
December 2019
3 Reads

Structures of enveloped virions determined by cryogenic electron microscopy and tomography.

Adv Virus Res 2019 20;105:35-71. Epub 2019 Aug 20.

Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Helsinki Institute of Life Science HiLIFE and Research Programme in Molecular and Integrative Biosciences, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland. Electronic address:

Enveloped viruses enclose their genomes inside a lipid bilayer which is decorated by membrane proteins that mediate virus entry. These viruses display a wide range of sizes, morphologies and symmetries. Spherical viruses are often isometric and their envelope proteins follow icosahedral symmetry. Read More

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http://dx.doi.org/10.1016/bs.aivir.2019.07.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112279PMC
December 2019
1 Read

Polyhedra, spindles, phage nucleus and pyramids: Structural biology of viral superstructures.

Adv Virus Res 2019 6;105:275-335. Epub 2019 Sep 6.

Infection & Immunity Program, Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia. Electronic address:

Viral infection causes comprehensive rearrangements of the cell that reflect as much host defense mechanisms as virus-induced structures assembled to facilitate infection. Regardless of their pro- or antiviral role, large intracellular structures are readily detectable by microscopy and often provide a signature characteristic of a specific viral infection. The structural features and localization of these assemblies have thus been commonly used for the diagnostic and classification of viruses since the early days of virology. Read More

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http://dx.doi.org/10.1016/bs.aivir.2019.08.001DOI Listing
December 2019

Illuminating the virus life cycle with single-molecule FRET imaging.

Adv Virus Res 2019 20;105:239-273. Epub 2019 Aug 20.

Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT, United States. Electronic address:

Single-molecule Förster resonance energy transfer (smFRET) imaging has emerged as a powerful tool to probe conformational dynamics of viral proteins, identify novel structural intermediates that are hiding in averaging population-based measurements, permit access to the energetics of transitions and as such to the precise molecular mechanisms of viral replication. One strength of smFRET is the capability of characterizing biological molecules in their fully hydrated/native state, which are not necessarily available to other structural methods. Elegant experimental design for physiologically relevant conditions, such as intact virions, has permitted the detection of previously unknown conformational states of viral glycoproteins, revealed asymmetric intermediates, and allowed access to the real-time imaging of conformational changes during viral fusion. Read More

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http://dx.doi.org/10.1016/bs.aivir.2019.07.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7246055PMC
December 2019
4 Reads

Structural mass spectrometry goes viral.

Adv Virus Res 2019 27;105:189-238. Epub 2019 Aug 27.

Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany; European XFEL GmbH, Schenefeld, Germany. Electronic address:

Over the last 20 years, mass spectrometry (MS), with its ability to analyze small sample amounts with high speed and sensitivity, has more and more entered the field of structural virology, aiming to investigate the structure and dynamics of viral proteins as close to their native environment as possible. The use of non-perturbing labels in hydrogen-deuterium exchange MS allows for the analysis of interactions between viral proteins and host cell factors as well as their dynamic responses to the environment. Cross-linking MS, on the other hand, can analyze interactions in viral protein complexes and identify virus-host interactions in cells. Read More

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http://dx.doi.org/10.1016/bs.aivir.2019.07.003DOI Listing
December 2019
1 Read

The application of atomic force microscopy for viruses and protein shells: Imaging and spectroscopy.

Authors:
Pedro J de Pablo

Adv Virus Res 2019 20;105:161-187. Epub 2019 Aug 20.

Departamento de Física de la Materia Condensada and Instituto de Física de la Materia Condensada (IFIMAC), Universidad Autónoma de Madrid, Madrid, Spain. Electronic address:

Atomic force microscopy (AFM) probes surface-adsorbed samples at the nanoscale by using a sharp stylus of nanometric size located at the end of a micro-cantilever. This technique can also work in a liquid environment and offers unique possibilities to study individual protein assemblies, such as viruses, under conditions that resemble their natural liquid milieu. Here, I show how AFM can be used to explore the topography of viruses and protein cages, including that of structures lacking a well-defined symmetry. Read More

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http://dx.doi.org/10.1016/bs.aivir.2019.07.006DOI Listing
December 2019

Structural analysis of pleomorphic and asymmetric viruses using cryo-electron tomography and subtomogram averaging.

Adv Virus Res 2019 27;105:117-159. Epub 2019 Aug 27.

Institute of Science and Technology Austria (IST Austria), Klosterneuburg, Austria. Electronic address:

Describing the protein interactions that form pleomorphic and asymmetric viruses represents a considerable challenge to most structural biology techniques, including X-ray crystallography and single particle cryo-electron microscopy. Obtaining a detailed understanding of these interactions is nevertheless important, considering the number of relevant human pathogens that do not follow strict icosahedral or helical symmetry. Cryo-electron tomography and subtomogram averaging methods provide structural insights into complex biological environments and are well suited to go beyond structures of perfectly symmetric viruses. Read More

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http://dx.doi.org/10.1016/bs.aivir.2019.07.008DOI Listing
December 2019
1 Read

The viral replication organelles within cells studied by electron microscopy.

Adv Virus Res 2019 19;105:1-33. Epub 2019 Aug 19.

Cell Structure Laboratory, National Center for Biotechnology, CSIC, Madrid, Spain. Electronic address:

Transmission electron microscopy (TEM) has been crucial to study viral infections. As a result of recent advances in light and electron microscopy, we are starting to be aware of the variety of structures that viruses assemble inside cells. Viruses often remodel cellular compartments to build their replication factories. Read More

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http://dx.doi.org/10.1016/bs.aivir.2019.07.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112055PMC
December 2019

How non-enveloped viruses hijack host machineries to cause infection.

Adv Virus Res 2019 2;104:97-122. Epub 2019 Jul 2.

Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI, United States; Cellular and Molecular Biology Program, University of Michigan Medical School, Ann Arbor, MI, United States. Electronic address:

Viruses must navigate the complex endomembranous network of the host cell to cause infection. In the case of a non-enveloped virus that lacks a surrounding lipid bilayer, endocytic uptake from the plasma membrane is not sufficient to cause infection. Instead, the virus must travel within organelle membranes to reach a specific cellular destination that supports exposure or arrival of the virus to the cytosol. Read More

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http://dx.doi.org/10.1016/bs.aivir.2019.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923802PMC
December 2019
2 Reads

Entry of bunyaviruses into plants and vectors.

Adv Virus Res 2019 9;104:65-96. Epub 2019 Aug 9.

Department of Entomology and Plant Pathology, North Carolina State University, Raleigh, NC, United States. Electronic address:

The majority of plant-infecting viruses are transmitted by arthropod vectors that deliver them directly into a living plant cell. There are diverse mechanisms of transmission ranging from direct binding to the insect stylet (non-persistent transmission) to persistent-propagative transmission in which the virus replicates in the insect vector. Despite this diversity in interactions, most arthropods that serve as efficient vectors have feeding strategies that enable them to deliver the virus into the plant cell without extensive damage to the plant and thus effectively inoculate the plant. Read More

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http://dx.doi.org/10.1016/bs.aivir.2019.07.001DOI Listing
December 2019

Gammaherpesvirus entry and fusion: A tale how two human pathogenic viruses enter their host cells.

Adv Virus Res 2019 17;104:313-343. Epub 2019 Jul 17.

Department of Microbiology and Immunology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.

The prototypical human γ-herpesviruses Epstein-Barr virus (EBV) and Kaposi Sarcoma-associated herpesvirus (KSHV) are involved in the development of malignancies. Like all herpesviruses, they share the establishment of latency, the typical architecture, and the conserved fusion machinery to initiate infection. The fusion machinery reflects virus-specific adaptations due to the requirements of the respective herpesvirus. Read More

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http://dx.doi.org/10.1016/bs.aivir.2019.05.006DOI Listing
December 2019
2 Reads

Entry of betaherpesviruses.

Adv Virus Res 2019 21;104:283-312. Epub 2019 Jun 21.

Division of Clinical Virology, Center for Infectious Diseases, Kobe University Graduate School of Medicine, Kobe, Japan. Electronic address:

In this chapter, we present an overview on betaherpesvirus entry, with a focus on human cytomegalovirus, human herpesvirus 6A and human herpesvirus 6B. Human cytomegalovirus (HCMV) is a complex human pathogen with a genome of 235kb encoding more than 200 genes. It infects a broad range of cell types by switching its viral ligand on the virion, using the trimer gH/gL/gO for infection of fibroblasts and the pentamer gH/gL/UL128/UL130/UL131 for infection of other cells such as epithelial and endothelial cells, leading to membrane fusion mediated by the fusion protein gB. Read More

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http://dx.doi.org/10.1016/bs.aivir.2019.05.005DOI Listing
December 2019
2 Reads

Common characteristics and unique features: A comparison of the fusion machinery of the alphaherpesviruses Pseudorabies virus and Herpes simplex virus.

Adv Virus Res 2019 3;104:225-281. Epub 2019 Jul 3.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Greifswald - Insel Riems, Germany.

Membrane fusion is a fundamental biological process that allows different cellular compartments delimited by a lipid membrane to release or exchange their respective contents. Similarly, enveloped viruses such as alphaherpesviruses exploit membrane fusion to enter and infect their host cells. For infectious entry the prototypic human Herpes simplex viruses 1 and 2 (HSV-1 and -2, collectively termed HSVs) and the porcine Pseudorabies virus (PrV) utilize four different essential envelope glycoproteins (g): the bona fide fusion protein gB and the regulatory heterodimeric gH/gL complex that constitute the "core fusion machinery" conserved in all members of the Herpesviridae; and the subfamily specific receptor binding protein gD. Read More

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http://dx.doi.org/10.1016/bs.aivir.2019.05.007DOI Listing
December 2019

Hantavirus entry: Perspectives and recent advances.

Adv Virus Res 2019 7;104:185-224. Epub 2019 Aug 7.

Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, United States. Electronic address:

Hantaviruses are important zoonotic pathogens of public health importance that are found on all continents except Antarctica and are associated with hemorrhagic fever with renal syndrome (HFRS) in the Old World and hantavirus pulmonary syndrome (HPS) in the New World. Despite the significant disease burden they cause, no FDA-approved specific therapeutics or vaccines exist against these lethal viruses. The lack of available interventions is largely due to an incomplete understanding of hantavirus pathogenesis and molecular mechanisms of virus replication, including cellular entry. Read More

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http://dx.doi.org/10.1016/bs.aivir.2019.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881143PMC
December 2019
4 Reads

Structural and cellular biology of rhabdovirus entry.

Adv Virus Res 2019 21;104:147-183. Epub 2019 Jun 21.

Institute for Integrative Biology of the Cell (I2BC), CEA, CNRS, University Paris-Sud, Université Paris-Saclay, Gif-sur-Yvette, France. Electronic address:

Rhabdoviruses are enveloped viruses with a negative-sense single strand RNA genome and are widespread among a great variety of organisms. In their membrane, they have a single glycoprotein (G) that mediates both virus attachment to cellular receptors and fusion between viral and endosomal membranes allowing viral genome release in the cytoplasm. We present structural and cellular aspects of Rhabdovirus entry into their host cell with a focus on vesicular stomatitis virus (VSV) and rabies virus (RABV) for which the early events of the viral cycle have been extensively studied. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00653527193001
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http://dx.doi.org/10.1016/bs.aivir.2019.05.003DOI Listing
December 2019
2 Reads

Developments in single-molecule and single-particle fluorescence-based approaches for studying viral envelope glycoprotein dynamics and membrane fusion.

Adv Virus Res 2019 27;104:123-146. Epub 2019 Jun 27.

Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA, United States. Electronic address:

Fusion of viral and cellular membranes is an essential step in the entry pathway of all enveloped viruses. This is a dynamic and multistep process, which has been extensively studied, resulting in the endpoints of the reaction being firmly established, and many essential cellular factors identified. What remains is to elucidate the dynamic events that underlie this process, including the order and timing of glycoprotein conformational changes, receptor-binding events, and movement of the glycoprotein on the surface of the virion. Read More

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http://dx.doi.org/10.1016/bs.aivir.2019.05.004DOI Listing
December 2019
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Key checkpoints in the movement of plant viruses through the host.

Adv Virus Res 2019 18;104:1-64. Epub 2019 Jul 18.

Instituto de Biología Molecular y Celular de Plantas (IBMCP), Universidad Politécnica de Valencia-Consejo Superior de Investigaciones Científicas, Valencia, Spain. Electronic address:

Plant viruses cannot exploit any of the membrane fusion-based routes of entry described for animal viruses. In addition, one of the distinctive structures of plant cells, the cell wall, acts as the first barrier against the invasion of pathogens. To overcome the rigidity of the cell wall, plant viruses normally take advantage of the way of life of different biological vectors. Read More

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http://dx.doi.org/10.1016/bs.aivir.2019.05.001DOI Listing
December 2019

Eukaryotic Circular Rep-Encoding Single-Stranded DNA (CRESS DNA) Viruses: Ubiquitous Viruses With Small Genomes and a Diverse Host Range.

Adv Virus Res 2019 5;103:71-133. Epub 2018 Dec 5.

Department of Ecology, Evolution and Natural Resources, Rutgers, the State University of New Jersey, New Brunswick, NJ, United States. Electronic address:

While single-stranded DNA (ssDNA) was once thought to be a relatively rare genomic architecture for viruses, modern metagenomics sequencing has revealed circular ssDNA viruses in most environments and in association with diverse hosts. In particular, circular ssDNA viruses encoding a homologous replication-associated protein (Rep) have been identified in the majority of eukaryotic supergroups, generating interest in the ecological effects and evolutionary history of circular Rep-encoding ssDNA viruses (CRESS DNA) viruses. This review surveys the explosion of sequence diversity and expansion of eukaryotic CRESS DNA taxonomic groups over the last decade, highlights similarities between the well-studied geminiviruses and circoviruses with newly identified groups known only through their genome sequences, discusses the ecology and evolution of eukaryotic CRESS DNA viruses, and speculates on future research horizons. Read More

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http://dx.doi.org/10.1016/bs.aivir.2018.10.001DOI Listing
April 2019
2 Reads

Phage Lysis: Multiple Genes for Multiple Barriers.

Adv Virus Res 2019 28;103:33-70. Epub 2018 Nov 28.

Department of Biochemistry & Biophysics, Center of Phage Technology, Texas A&M University, College Station, TX, United States.

The first steps in phage lysis involve a temporally controlled permeabilization of the cytoplasmic membrane followed by enzymatic degradation of the peptidoglycan. For Caudovirales of Gram-negative hosts, there are two different systems: the holin-endolysin and pinholin-SAR endolysin pathways. In the former, lysis is initiated when the holin forms micron-scale holes in the inner membrane, releasing active endolysin into the periplasm to degrade the peptidoglycan. Read More

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http://dx.doi.org/10.1016/bs.aivir.2018.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733033PMC
April 2019
3 Reads

Evolution of the Large Nucleocytoplasmic DNA Viruses of Eukaryotes and Convergent Origins of Viral Gigantism.

Adv Virus Res 2019 10;103:167-202. Epub 2018 Nov 10.

National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, United States.

The Nucleocytoplasmic Large DNA Viruses (NCLDV) of eukaryotes (proposed order "Megavirales") comprise an expansive group of eukaryotic viruses that consists of the families Poxviridae, Asfarviridae, Iridoviridae, Ascoviridae, Phycodnaviridae, Marseilleviridae, Pithoviridae, and Mimiviridae, as well as Pandoraviruses, Molliviruses, and Faustoviruses that so far remain unaccounted by the official virus taxonomy. All these viruses have double-stranded DNA genomes that range in size from about 100 kilobases (kb) to more than 2.5 megabases. Read More

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http://dx.doi.org/10.1016/bs.aivir.2018.09.002DOI Listing
April 2019
6 Reads

The Complex Nature of Tupanviruses.

Adv Virus Res 2019 10;103:135-166. Epub 2018 Nov 10.

Laboratório de Vírus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil. Electronic address:

The discovery of giant viruses revealed a new level of complexity in the virosphere, raising important questions about the diversity, ecology, and evolution of these viruses. The family Mimiviridae was the first group of amoebal giant viruses to be discovered (by Bernard La Scola and Didier Raoult team), containing viruses with structural and genetic features that challenged many concepts of classic virology. The tupanviruses are among the newest members of this family and exhibit structural, biological, and genetic features never previously observed in other giant viruses. Read More

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http://dx.doi.org/10.1016/bs.aivir.2018.09.001DOI Listing
April 2019
7 Reads

The Diverse Impacts of Phage Morons on Bacterial Fitness and Virulence.

Adv Virus Res 2019 3;103:1-31. Epub 2018 Oct 3.

Department of Biochemistry, University of Toronto, Toronto, ON, Canada. Electronic address:

The viruses that infect bacteria, known as phages, are the most abundant biological entity on earth. They play critical roles in controlling bacterial populations through phage-mediated killing, as well as through formation of bacterial lysogens. In this form, the survival of the phage depends on the survival of the bacterial host in which it resides. Read More

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http://dx.doi.org/10.1016/bs.aivir.2018.08.001DOI Listing
April 2019
5 Reads

Tobamoviruses as Models for the Study of Virus Evolution.

Adv Virus Res 2018 26;102:89-117. Epub 2018 Jul 26.

Centro de Biotecnología y Genómica de Plantas UPM-INIA, and E.T.S.I., Agronómica, Alimentaria y de Biosistemas, Universidad Politécnica de Madrid, Madrid, Spain. Electronic address:

The study of tobacco mosaic virus and other tobamovirus species has greatly contributed to the development of all areas of virology, including virus evolution. Research with tobamoviruses has been pioneer, or particularly significant, in all major areas of research in this field, including: the characterization of the genetic diversity of virus populations, the mechanisms and rates of generation of genetic diversity, the analysis of the genetic structure of virus populations and of the factors that shape it, the adaptation of viruses to hosts and the evolution of host range, and the evolution of virus taxa and of virus-host interactions. Many of these continue to be hot topics in evolutionary biology, or have been identified recently as such, including (i) host-range evolution, (ii) predicting the overcoming of resistance in crops, (iii) trade-offs between virus life-history traits in virus evolution, and (iv) the codivergence of viruses and hosts at different taxonomical and spatial scales. Read More

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http://dx.doi.org/10.1016/bs.aivir.2018.06.006DOI Listing
December 2018
3 Reads

Molecular Modeling for Better Understanding of Cucumovirus Pathology.

Adv Virus Res 2018 26;102:59-88. Epub 2018 Jul 26.

MTA ATK, Agricultural Institute, Centre for Agricultural Research, Hungarian Academy of Sciences, Budapest, Hungary. Electronic address:

Cucumber mosaic virus (CMV) is a small RNA virus capable of infecting a wide variety of plant species. The high economic losses due to the CMV infection made this virus a relevant subject of scientific studies, which were further facilitated by the small size of the viral genome. Hence, CMV also became a model organism to investigate the molecular mechanism of pathogenesis. Read More

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http://dx.doi.org/10.1016/bs.aivir.2018.06.002DOI Listing
December 2018
3 Reads

Development of Model Systems for Plant Rhabdovirus Research.

Adv Virus Res 2018 30;102:23-57. Epub 2018 Jul 30.

State Key Laboratory of Rice Biology, Institute of Biotechnology, Zhejiang University, Hangzhou, China.

This chapter reviews the discoveries and initial characterizations (1930-1990) of three plant rhabdoviruses, sonchus yellow net virus, potato yellow dwarf virus, and lettuce necrotic yellows virus, that have become model systems for research on this group of enveloped negative-strand RNA plant viruses. We have used our personal perspectives to review the early historical studies of these viruses, the important technologies and tools, such as density gradient centrifugation, that were developed during the research, and to highlight the eminent scientists involved in these discoveries. Early studies on sites of virus replication, virion structure, physicochemical composition, and the use of protoplasts and vector insect cell culture for virus research are discussed, and differences between the nuclear and cytoplasmic lifestyles of plant rhabdoviruses are contrasted. Read More

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http://dx.doi.org/10.1016/bs.aivir.2018.06.008DOI Listing
December 2018
4 Reads

Integration of Omics Approaches toward Understanding Whitefly Transmission of Viruses.

Adv Virus Res 2018 26;102:199-223. Epub 2018 Jul 26.

USDA-ARS, Salinas, CA, United States. Electronic address:

Viruses transmitted by whiteflies are predominantly classified as having either persistent circulative or semipersistent transmission, and the majority of studies have addressed transmission of viruses in the genera Begomovirus (family Geminiviridae) and Crinivirus (family Closteroviridae), respectively. Early studies on vector transmission primarily addressed individual aspects of transmission; however, with the breadth of new technology now available, an increasingly greater number of studies involve coordinated research that is beginning to assemble a more complete picture of how whiteflies and viruses have coevolved to facilitate transmission. In particular the integration of gene expression and metabolomic studies into broader research topics is providing knowledge of changes within the whitefly vector in response to the presence of viruses that would have been impossible to identify previously. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00653527183003
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http://dx.doi.org/10.1016/bs.aivir.2018.06.005DOI Listing
December 2018
33 Reads

Viral Manipulation of Plant Stress Responses and Host Interactions With Insects.

Adv Virus Res 2018 25;102:177-197. Epub 2018 Jul 25.

Department of Plant Sciences, University of Cambridge, Cambridge, United Kingdom.

Do the alterations in plant defensive signaling and metabolism that occur in susceptible hosts following virus infection serve any purpose beyond directly aiding viruses to replicate and spread? Or indeed, are these modifications to host phenotype purely incidental consequences of virus infection? A growing body of data, in particular from studies of viruses vectored by whiteflies and aphids, indicates that viruses influence the efficiency of their own transmission by insect vectors and facilitate mutualistic relationships between viruses and their insect vectors. Furthermore, it appears that viruses may be able to increase the opportunity for transmission in the long term by providing reward to the host plants that they infect. This may be conditional, for example, by aiding host survival under conditions of drought or cold or, more surprisingly, by helping plants attract beneficial insects such as pollinators. Read More

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http://dx.doi.org/10.1016/bs.aivir.2018.06.004DOI Listing
December 2018
34 Reads

TMV Particles: The Journey From Fundamental Studies to Bionanotechnology Applications.

Adv Virus Res 2018 26;102:149-176. Epub 2018 Jul 26.

Department of Molecular Biology and Plant Virology, Institute of Biomaterials and Biomolecular Systems, University of Stuttgart, Stuttgart, Germany.

Ever since its initial characterization in the 19th century, tobacco mosaic virus (TMV) has played a prominent role in the development of modern virology and molecular biology. In particular, research on the three-dimensional structure of the virus particles and the mechanism by which these assemble from their constituent protein and RNA components has made TMV a paradigm for our current view of the morphogenesis of self-assembling structures, including viral particles. More recently, this knowledge has been applied to the development of novel reagents and structures for applications in biomedicine and bionanotechnology. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00653527183003
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http://dx.doi.org/10.1016/bs.aivir.2018.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112118PMC
December 2018
9 Reads

Dichorhaviruses in their Host Plants and Mite Vectors.

Adv Virus Res 2018 26;102:119-148. Epub 2018 Jul 26.

Departmento de Fitopatologia e Nematologia, ESALQ/USP, Piracicaba, Brazil.

A group of related bacilliform, nuclear viruses with a bisegmented negative-sense RNA genome that are transmitted by Brevipalpus mites likely in a circulative-propagative manner were recently classified in the new genus Dichorhavirus, family Rhabdoviridae. These viruses cause localized lesions on leaves, stems, and fruits of economically significant horticultural and ornamental plant species. Among its members, orchid fleck virus, citrus leprosis virus N, and coffee ringspot virus are most prominent. Read More

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http://dx.doi.org/10.1016/bs.aivir.2018.06.001DOI Listing
December 2018
30 Reads

Preface.

Adv Virus Res 2018 ;101:xiii-xiv

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http://dx.doi.org/10.1016/S0065-3527(18)30032-0DOI Listing
March 2020
3 Reads

Water-Mediated Transmission of Plant, Animal, and Human Viruses.

Adv Virus Res 2018 26;101:85-128. Epub 2018 Apr 26.

National Institute of Biology, Ljubljana, Slovenia. Electronic address:

Viruses represent the most abundant and diverse of the biological entities in environmental waters, including the seas and probably also freshwater systems. They are important players in ecological networks in waters and influence global biochemical cycling and community composition dynamics. Among the many diverse viruses from terrestrial environments found in environmental waters, some are plant, animal, and/or human pathogens. Read More

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http://dx.doi.org/10.1016/bs.aivir.2018.02.004DOI Listing
November 2018
9 Reads

From Spatial Metagenomics to Molecular Characterization of Plant Viruses: A Geminivirus Case Study.

Adv Virus Res 2018 7;101:55-83. Epub 2018 May 7.

CIRAD, UMR BGPI, Montpellier, France; BGPI, Univ. Montpellier, CIRAD, INRA, Montpellier SupAgro, Montpellier, France. Electronic address:

The number of plant viruses that are known likely remains only a vanishingly small fraction of all extant plant virus species. Consequently, the distribution and population dynamics of plant viruses within even the best-studied ecosystems have only ever been studied for small groups of virus species. Even for the best studied of these groups very little is known about virus diversity at spatial scales ranging from an individual host, through individual local host populations to global host populations. Read More

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http://dx.doi.org/10.1016/bs.aivir.2018.02.003DOI Listing
November 2018
10 Reads

Viruses in Polar Lake and Soil Ecosystems.

Adv Virus Res 2018 26;101:39-54. Epub 2018 Apr 26.

Centro de Biología Molecular Severo Ochoa (Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid), Madrid, Spain. Electronic address:

Viruses play an important role in the control of microbial communities, and it has been suggested that the influence of viruses in polar ecosystems, with low nutrients and under extreme environmental conditions, may be greater. Viral metagenomics allows the genetic characterization of complex viral communities without the need to isolate and grow viruses. Recent investigations in Antarctica and the Arctic are uncovering a great diversity of DNA viruses, including bacteriophages, circular single-stranded DNA viruses, algal-infecting phycodnaviruses, and virophages, adapted to these extreme environments. Read More

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http://dx.doi.org/10.1016/bs.aivir.2018.02.002DOI Listing
November 2018
3 Reads

Ecological Complexity in Plant Virus Host Range Evolution.

Adv Virus Res 2018 26;101:293-339. Epub 2018 Apr 26.

Centro de Biotecnología y Genómica de Plantas UPM-INIA, and E.T.S.I. Agrícola, Alimentaria y de Biosistemas, Campus de Montegancedo, Universidad Politécnica de Madrid, Madrid, Spain. Electronic address:

The host range of a plant virus is the number of species in which it can reproduce. Most studies of plant virus host range evolution have focused on the genetics of host-pathogen interactions. However, the distribution and abundance of plant viruses and their hosts do not always overlap, and these spatial and temporal discontinuities in plant virus-host interactions can result in various ecological processes that shape host range evolution. Read More

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http://dx.doi.org/10.1016/bs.aivir.2018.02.009DOI Listing
November 2018
3 Reads

Emerging Viruses in Bees: From Molecules to Ecology.

Adv Virus Res 2018 7;101:251-291. Epub 2018 May 7.

School of Biological Sciences, Royal Holloway University of London, Egham, United Kingdom.

Emerging infectious diseases arise as a result of novel interactions between populations of hosts and pathogens, and can threaten the health and wellbeing of the entire spectrum of biodiversity. Bees and their viruses are a case in point. However, detailed knowledge of the ecological factors and evolutionary forces that drive disease emergence in bees and other host-pathogen communities is surprisingly lacking. Read More

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http://dx.doi.org/10.1016/bs.aivir.2018.02.008DOI Listing
November 2018
3 Reads

Evolutionary Determinants of Host and Vector Manipulation by Plant Viruses.

Adv Virus Res 2018 7;101:189-250. Epub 2018 May 7.

Department of Applied Ecology, North Carolina State University, Raleigh, NC, United States.

Plant viruses possess adaptations for facilitating acquisition, retention, and inoculation by vectors. Until recently, it was hypothesized that these adaptations are limited to virus proteins that enable virions to bind to vector mouthparts or invade their internal tissues. However, increasing evidence suggests that viruses can also manipulate host plant phenotypes and vector behaviors in ways that enhance their own transmission. Read More

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http://dx.doi.org/10.1016/bs.aivir.2018.02.007DOI Listing
November 2018
2 Reads

Plant and Insect Viruses in Managed and Natural Environments: Novel and Neglected Transmission Pathways.

Authors:
Roger A C Jones

Adv Virus Res 2018 26;101:149-187. Epub 2018 Apr 26.

Institute of Agriculture, Faculty of Science, University of Western Australia, Crawley, WA, Australia; Department of Primary Industries and Regional Development, South Perth, WA, Australia. Electronic address:

The capacity to spread by diverse transmission pathways enhances a virus' ability to spread effectively and survive when circumstances change. This review aims to improve understanding of how plant and insect viruses spread through natural and managed environments by drawing attention to 12 novel or neglected virus transmission pathways whose contribution is underestimated. For plant viruses, the pathways reviewed are vertical and horizontal transmission via pollen, and horizontal transmission by parasitic plants, natural root grafts, wind-mediated contact, chewing insects, and contaminated water or soil. Read More

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http://dx.doi.org/10.1016/bs.aivir.2018.02.006DOI Listing
November 2018
3 Reads
4.571 Impact Factor

Evaluating the Importance of Environmental Persistence for Ranavirus Transmission and Epidemiology.

Adv Virus Res 2018 26;101:129-148. Epub 2018 Apr 26.

School of Biological Sciences, Washington State University, Pullman, WA, United States.

Viruses persist outside their hosts in a variety of forms, from naked virions to virus protected in sloughed tissues or carcasses, and for a range of times, all of which affect the likelihood and importance of transmission from the environment. This review synthesizes the literature on environmental persistence of viruses in the genus Ranavirus (family Iridoviridae), which are large double-stranded DNA viruses of ectothermic, often aquatic or semiaquatic vertebrates. Ranaviruses have been associated with mass mortality events in natural and captive settings around the world, and with population and community-wide declines in Europe. Read More

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http://dx.doi.org/10.1016/bs.aivir.2018.02.005DOI Listing
November 2018
3 Reads

Viruses in Marine Ecosystems: From Open Waters to Coral Reefs.

Authors:
Karen D Weynberg

Adv Virus Res 2018 7;101:1-38. Epub 2018 May 7.

School of Chemistry & Molecular Biosciences, University of Queensland, Brisbane, QLD, Australia. Electronic address:

Viruses infect all kingdoms of marine life from bacteria to whales. Viruses in the world's oceans play important roles in the mortality of phytoplankton, and as drivers of evolution and biogeochemical cycling. They shape host population abundance and distribution and can lead to the termination of algal blooms. Read More

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http://dx.doi.org/10.1016/bs.aivir.2018.02.001DOI Listing
November 2018
4 Reads

Preface to Volume 100: History and Looking Forward.

Adv Virus Res 2018;100:xv-xxiv

Pennsylvania State University, Philadelphia, PA, United States.

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http://dx.doi.org/10.1016/S0065-3527(18)30021-6DOI Listing
September 2018
5 Reads

Viruses of Plant-Interacting Fungi.

Adv Virus Res 2018 21;100:99-116. Epub 2017 Nov 21.

Institute of Plant Science and Resources (IPSR), Okayama University, Kurashiki, Japan. Electronic address:

Plant-associated fungi are infected by viruses at the incidence rates from a few % to over 90%. Multiple viruses often coinfect fungal hosts, and occasionally alter their phenotypes, but most of the infections are asymptomatic. Phenotypic alterations are grouped into two types: harmful or beneficial to the host fungi. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00653527173002
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http://dx.doi.org/10.1016/bs.aivir.2017.10.003DOI Listing
December 2018
8 Reads

Morbillivirus Pathogenesis and Virus-Host Interactions.

Adv Virus Res 2018 1;100:75-98. Epub 2018 Feb 1.

Paul-Ehrlich-Institut, Langen, Germany. Electronic address:

Despite the availability of safe and effective vaccines against measles and several animal morbilliviruses, they continue to cause regular outbreaks and epidemics in susceptible populations. Morbilliviruses are highly contagious and share a similar pathogenesis in their respective hosts. This review provides an overview of morbillivirus history and the general replication cycle and recapitulates Morbillivirus pathogenesis focusing on common and unique aspects seen in different hosts. Read More

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http://dx.doi.org/10.1016/bs.aivir.2017.12.003DOI Listing
December 2018
7 Reads

African Swine Fever Virus Biology and Vaccine Approaches.

Adv Virus Res 2018 21;100:41-74. Epub 2017 Nov 21.

Diagnostic Medicine/Pathobiology, Center of Excellence for Emerging and Zoonotic Animal Diseases (CEEZAD), College of Veterinary Medicine, Kansas State University, Manhattan, KS, United States. Electronic address:

African swine fever (ASF) is an acute and often fatal disease affecting domestic pigs and wild boar, with severe economic consequences for affected countries. ASF is endemic in sub-Saharan Africa and the island of Sardinia, Italy. Since 2007, the virus emerged in the republic of Georgia, and since then spread throughout the Caucasus region and Russia. Read More

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http://dx.doi.org/10.1016/bs.aivir.2017.10.002DOI Listing
December 2018
62 Reads