424 results match your criteria Advances in radiation oncology[Journal]


Stereotactic Body Radiation Therapy to a Splenic Metastasis in Oligoprogressive Non-small Cell Lung Cancer.

Adv Radiat Oncol 2020 May-Jun;5(3):516-521. Epub 2019 Dec 31.

Departments of Radiation Oncology, Dana-Farber Cancer Institute/Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.adro.2019.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276683PMC
December 2019

Bronchopleural Fistula After Concurrent Chemoradiotherapy.

Adv Radiat Oncol 2020 May-Jun;5(3):511-515. Epub 2020 Jan 12.

Department of Surgery, Zuyderland Medical Center, Heerlen, the Netherlands.

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http://dx.doi.org/10.1016/j.adro.2019.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276680PMC
January 2020

Stereotactic Body Radiation Therapy for the Definitive Treatment of Early Stage Kidney Cancer: A Survival Comparison With Surgery, Tumor Ablation, and Observation.

Adv Radiat Oncol 2020 May-Jun;5(3):495-502. Epub 2020 Jan 21.

Radiation Oncology, MD Anderson Cancer Center, Houston, Texas.

Purpose: Partial nephrectomy is the preferred definitive treatment for early stage kidney cancer, with tumor ablative techniques or active surveillance reserved for patients not undergoing surgery. Stereotactic body radiation therapy (SBRT) has emerged as a potential noninvasive alternative for patients with early stage kidney cancer not amenable to surgery, with early reports suggesting excellent rates of local control and limited toxicity.

Methods And Materials: The national cancer database from 2004 to 2014 was queried for patients who received a diagnosis of T1N0M0 kidney cancer. Read More

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http://dx.doi.org/10.1016/j.adro.2020.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276675PMC
January 2020

A Model to Improve the Workflow for Radiation Treatments in the Era of Bundled Payments: A Quality Improvement Project Report.

Adv Radiat Oncol 2020 May-Jun;5(3):490-494. Epub 2020 Jan 21.

Department of Radiation Oncology, University of Mississippi Medical Center, Jackson, Mississippi.

The Centers for Medicare and Medicaid Services has proposed alternate payment models to improve the efficiency and decrease the redundancy of health care. Bundled payments or episode-based care is one example. Herein, we report on the successful implementation of a quality improvement project in which changing the clinical workflow for postoperative radiation treatment to the hip to prevent heterotopic ossification improved the efficiency of patient care and decreased cost by eliminating redundant imaging through multidisciplinary participation. Read More

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http://dx.doi.org/10.1016/j.adro.2019.12.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276685PMC
January 2020

Intracranial Stereotactic Radiation Therapy With a Jawless Ring Gantry Linear Accelerator Equipped With New Dual Layer Multileaf Collimator.

Adv Radiat Oncol 2020 May-Jun;5(3):482-489. Epub 2020 Jan 28.

Department of Radiation Oncology, Washington University School of Medicine, St. Louis, Missouri.

Purpose: To test the feasibility of a simplified, robust, workflow for intracranial stereotactic radiation therapy (SRT) using a ring gantry linear accelerator (RGLA) equipped with a dual-layer stacked, staggered, and interdigitating multileaf collimator.

Materials And Methods: Twenty recent clinical SRT cases treated using a radiosurgery c-arm linear accelerator were anonymized. From these data sets, a new planning workflow was developed and used to replan these cases, which then were compared to their clinical counterparts. Read More

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http://dx.doi.org/10.1016/j.adro.2020.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276691PMC
January 2020

Segmentation of the Prostatic Gland and the Intraprostatic Lesions on Multiparametic Magnetic Resonance Imaging Using Mask Region-Based Convolutional Neural Networks.

Adv Radiat Oncol 2020 May-Jun;5(3):473-481. Epub 2020 Feb 8.

Department of Radiation Oncology, Henry Ford Health System, Detroit, Michigan.

Purpose: Accurate delineation of the prostate gland and intraprostatic lesions (ILs) is essential for prostate cancer dose-escalated radiation therapy. The aim of this study was to develop a sophisticated deep neural network approach to magnetic resonance image analysis that will help IL detection and delineation for clinicians.

Methods And Materials: We trained and evaluated mask region-based convolutional neural networks to perform the prostate gland and IL segmentation. Read More

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http://dx.doi.org/10.1016/j.adro.2020.01.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280293PMC
February 2020

Characterization of Respiration-Induced Motion in Prone Versus Supine Patient Positioning for Thoracic Radiation Therapy.

Adv Radiat Oncol 2020 May-Jun;5(3):466-472. Epub 2020 Feb 28.

Department of Radiation Oncology, Virginia Commonwealth University, Richmond, Virginia.

Purpose: Variations in the breathing characteristics, both on short term (intrafraction) and long term (interfraction) time scales, may adversely affect the radiation therapy process at all stages when treating lung tumors. Prone position has been shown to improve consistency (ie, reduced intrafraction variability) and reproducibility (ie, reduced interfraction variability) of the respiratory pattern with respect to breathing amplitude and period as a result of natural abdominal compression, with no active involvement required from the patient. The next natural step in investigating breathing-induced changes is to evaluate motion amplitude changes between prone and supine targets or organs at risk, which is the purpose of the present study. Read More

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http://dx.doi.org/10.1016/j.adro.2020.02.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276676PMC
February 2020

Variations Between Dose-Ventilation and Dose-Perfusion Metrics in Radiation Therapy Planning for Lung Cancer.

Adv Radiat Oncol 2020 May-Jun;5(3):459-465. Epub 2020 Mar 20.

Department of Radiation Oncology, University of California Davis School of Medicine, Sacramento, California.

Purpose: Currently, several active clinical trials of functional lung avoidance radiation therapy using different imaging modalities for ventilation or perfusion are underway. Patients with lung cancer often show ventilation-perfusion mismatch, whereas the significance of dose-function metric remains unclear. The aim of the present study was to compare dose-ventilation metrics with dose-perfusion metrics for radiation therapy plan evaluation. Read More

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http://dx.doi.org/10.1016/j.adro.2020.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280081PMC

Early Outcomes of Patients With Locally Advanced Non-small Cell Lung Cancer Treated With Intensity-Modulated Proton Therapy Versus Intensity-Modulated Radiation Therapy: The Mayo Clinic Experience.

Adv Radiat Oncol 2020 May-Jun;5(3):450-458. Epub 2019 Aug 21.

Department of Radiation Oncology, Mayo Clinic, Phoenix, Arizona.

Purpose: There are very little data available comparing outcomes of intensity-modulated proton therapy (IMPT) to intensity-modulated radiation therapy (IMRT) in patients with locally advanced NSCLC (LA-NSCLC).

Methods: Seventy-nine consecutively treated patients with LA-NSCLC underwent definitive IMPT ( = 33 [42%]) or IMRT ( = 46 [58%]) from 2016 to 2018 at our institution. Survival rates were calculated using the Kaplan-Meier method and compared with the log-rank test. Read More

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http://dx.doi.org/10.1016/j.adro.2019.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276663PMC

Outpatient Anesthesia Facilitates Stereotactic Body Radiation Therapy for Early Stage Lung Cancer Patients With Advanced Cognitive Impairments.

Adv Radiat Oncol 2020 May-Jun;5(3):444-449. Epub 2019 Oct 14.

Department of Radiation Oncology, Taussig Cancer Centre, Cleveland Clinic, Cleveland, Ohio.

Purpose: To report on the use of outpatient anesthesia (OPA) facilitating delivery of stereotactic body radiation therapy (SBRT) in patients with severe cognitive impairments (CI) diagnosed with inoperable early stage lung cancer.

Methods And Materials: We surveyed our institutional review board-approved prospective lung SBRT data registry to document the feasibility of using anesthesia in CI patients and to determine their SBRT outcomes.

Results: From 2004 to 2018, 8 from a total 2084 patients were identified for this analysis. Read More

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http://dx.doi.org/10.1016/j.adro.2019.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276662PMC
October 2019

Scanning Beam Proton Therapy versus Photon IMRT for Stage III Lung Cancer: Comparison of Dosimetry, Toxicity, and Outcomes.

Adv Radiat Oncol 2020 May-Jun;5(3):434-443. Epub 2020 Mar 20.

Departments of Radiation Oncology, Seattle, Washington.

Purpose: There are limited clinical data on scanning-beam proton therapy (SPT) in treating locally advanced lung cancer, as most published studies have used passive-scatter technology. There is increasing interest in whether the dosimetric advantages of SPT compared with photon therapy can translate into superior clinical outcomes. We present our experience of SPT and photon intensity modulated radiation therapy (IMRT) with clinical dosimetry and outcomes in patients with stage III lung cancer. Read More

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http://dx.doi.org/10.1016/j.adro.2020.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276696PMC

Impact of Respiratory Developmental Stage on Sensitivity to Late Effects of Radiation in Pediatric Cancer Survivors.

Adv Radiat Oncol 2020 May-Jun;5(3):426-433. Epub 2019 Dec 11.

Departments of Radiation Oncology and Pediatrics, University of Rochester Medical Center, Rochester, New York.

Purpose: Pulmonary dysfunction is a prevalent and potentially debilitating late effect of pediatric cancer treatment. We postulated that age, as a surrogate for respiratory developmental status, might be associated with vulnerability to pulmonary injury.

Materials And Methods: Sixty-one children treated with lung radiation at our institution who had undergone a pulmonary function test (PFT) between 1995 and 2016 were analyzed. Read More

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http://dx.doi.org/10.1016/j.adro.2019.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276690PMC
December 2019

The Impact of High-Dose-Rate Brachytherapy: Measuring Clinical Outcomes in the Primary Treatment of Cervical Cancer.

Adv Radiat Oncol 2020 May-Jun;5(3):419-425. Epub 2020 Feb 28.

Division of Radiation Oncology, The Ottawa Hospital, Ottawa Ontario, Canada.

Purpose: Radical concurrent chemoradiotherapy with combined external beam radiotherapy (EBRT) and brachytherapy is used to treat locally advanced cervical cancer. Our institution has transitioned to high-dose-rate (HDR) intracavitary brachytherapy (ICBT) from low-dose-rate (LDR) brachytherapy in 2008, and a review was conducted on the effect of this change on patient outcomes.

Methods And Materials: A single-arm retrospective chart review was performed on locally advanced (Fédération Internationale de Gynécologie et d'Obstétrique stage IB-IVA) patients with cervical cancer treated with combined external beam radiation therapy and HDR-ICBT with curative intent between 2008 and 2014. Read More

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http://dx.doi.org/10.1016/j.adro.2020.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276688PMC
February 2020

Patterns of Care and Outcomes for Small Cell Carcinoma of the Cervix: A National Retrospective Analysis of 542 Cases.

Adv Radiat Oncol 2020 May-Jun;5(3):412-418. Epub 2019 Aug 31.

Department of Radiation Oncology, Vanderbilt University, Nashville, Tennessee.

Purpose: Small cell carcinoma of the cervix (SCCC) represents 1% to 5% of cervical cancers, with limited data on management and outcomes. We evaluated patterns of care and outcomes for SCCC using the National Cancer Database.

Methods And Materials: This retrospective cohort study of SCCC (2004-2011) included 542 cases. Read More

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http://dx.doi.org/10.1016/j.adro.2019.08.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276665PMC

Gantry-Mounted Linear Accelerator-Based Stereotactic Body Radiation Therapy for Low- and Intermediate-Risk Prostate Cancer.

Adv Radiat Oncol 2020 May-Jun;5(3):404-411. Epub 2019 Oct 14.

Department of Radiation Oncology, University of California, Los Angeles, California.

Purpose: To establish the safety and efficacy of gantry-mounted linear accelerator-based stereotactic body radiation therapy (SBRT) for low- and intermediate-risk prostate cancer.

Methods: We pooled 921 patients enrolled on 7 single-institution prospective phase II trials of gantry-based SBRT from 2006 to 2017. The cumulative incidences of biochemical recurrence (defined by the Phoenix definition) and physician-scored genitourinary (GU) and gastrointestinal (GI) toxicities (defined per the original trials using Common Terminology Criteria for Adverse Events) were estimated using a competing risk framework. Read More

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http://dx.doi.org/10.1016/j.adro.2019.09.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276661PMC
October 2019

Ten-Year Results From a Phase II Study on Image Guided, Intensity Modulated Radiation Therapy With Simultaneous Integrated Boost in High-Risk Prostate Cancer.

Adv Radiat Oncol 2020 May-Jun;5(3):396-403. Epub 2019 Dec 9.

Department of Oncology and Institute of Clinical Science, Haukeland University Hospital, Bergen, Norway.

Purpose: There is no consensus on how to treat high-risk prostate cancer, and long-term results from hypofractionated radiation therapy are lacking. We report 10-year results after image guided, intensity modulated radiation therapy with hypofractionated simultaneous integrated boost and elective pelvic field.

Methods And Materials: Between 2007 and 2009, 97 consecutive patients with high-risk prostate cancer were included, treated with 2. Read More

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http://dx.doi.org/10.1016/j.adro.2019.11.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276692PMC
December 2019

Building a High-Dose-Rate Prostate Brachytherapy Program With Real-Time Ultrasound-Based Planning: Initial Safety, Quality, and Outcome Results.

Adv Radiat Oncol 2020 May-Jun;5(3):388-395. Epub 2020 Feb 21.

Department of Radiation Oncology, University of Rochester Medical Center, Rochester, New York.

Purpose: Growing evidence supports the efficacy and safety of high-dose-rate (HDR) brachytherapy as a boost or monotherapy in prostate cancer treatment. We initiated a new HDR prostate brachytherapy practice in April 2014. Here, we report the learning experiences, short-term safety, quality, and outcome. Read More

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http://dx.doi.org/10.1016/j.adro.2020.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276678PMC
February 2020

How Much Was the Elective Lymph Node Region Covered in Involved-Field Radiation Therapy for Locally Advanced Pancreatic Cancer? Evaluation of Overlap Between Gross Target Volume and Celiac Artery-Superior Mesenteric Artery Lymph Node Regions.

Adv Radiat Oncol 2020 May-Jun;5(3):377-387. Epub 2019 Sep 13.

Department of Radiation Oncology, National Cancer Center Hospital, Tokyo, Japan.

Purpose: The purpose of this study was to investigate the overlaps between gross target volume (GTV) and the celiac artery (CA) and superior mesenteric artery (SMA) lymph node regions and to examine the dose incidentally irradiated to the CA and SMA lymph node regions by involved-field radiation therapy (IFRT) for locally advanced pancreatic cancer (LAPC).

Methods And Materials: Fifty-nine patients who had LAPC without distant metastasis were included. They received IFRT at 50. Read More

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http://dx.doi.org/10.1016/j.adro.2019.08.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278027PMC
September 2019

IMRT Reduces Acute Toxicity in Patients Treated With Preoperative Chemoradiation for Gastric Cancer.

Adv Radiat Oncol 2020 May-Jun;5(3):369-376. Epub 2019 Nov 28.

Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas.

Purpose: Preoperative chemoradiation is being currently evaluated in 2 randomized international trials. However, chemoradiation for gastric cancer can be associated with relatively high rates of acute toxicity. We compared rates of toxicity, toxicity-related events, and oncologic outcomes in patients treated with intensity modulated radiation therapy (IMRT) and those treated with 3-dimensional conformal radiation therapy (3DCRT). Read More

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http://dx.doi.org/10.1016/j.adro.2019.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276694PMC
November 2019

A Cohort Study of Stereotactic Radiosurgery Results for Patients With 5 to 15 Versus 2 to 4 Brain Metastatic Tumors.

Adv Radiat Oncol 2020 May-Jun;5(3):358-368. Epub 2019 Nov 26.

Katsuta Hospital Mito GammaHouse, Hitachi-naka, Japan.

Purpose: The role of stereotactic radiosurgery (SRS) alone for patients with ≥5 brain metastases is not fully understood. The objective of the study was to compare SRS-alone treatment results for 2 to 4 versus 5 to 15 tumors.

Methods And Materials: This was an institutional review board-approved, retrospective cohort study using our prospectively accumulated database including 1150 patients with 2 to 4 tumors and 939 with 5 to 15 tumors who underwent Gamma Knife SRS during a 20-year period (1998-2018). Read More

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http://dx.doi.org/10.1016/j.adro.2019.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276677PMC
November 2019

Neurological Death is Common in Patients With EGFR Mutant Non-Small Cell Lung Cancer Diagnosed With Brain Metastases.

Adv Radiat Oncol 2020 May-Jun;5(3):350-357. Epub 2019 Nov 26.

Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.

Purpose: Brain metastases (BrM) are common in patients with epidermal growth factor receptor (EGFRm) mutant non-small cell lung cancer (NSCLC). We sought to determine the rate of neurologic death (ND) in this population.

Methods And Materials: We analyzed data from 198 patients who received a diagnosis of BrM from EGFRm NSCLC between 2004 and 2016, comparing patients whose initial treatment for BrM was stereotactic radiosurgery with or without tyrosine kinase inhibitors (TKI), whole brain radiation therapy (WBRT) with or without TKI, or TKI alone. Read More

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http://dx.doi.org/10.1016/j.adro.2019.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276684PMC
November 2019

Impact of Adjuvant Radiation Therapy in Patients With Male Breast Cancer: A Multicenter International Analysis.

Adv Radiat Oncol 2020 May-Jun;5(3):345-349. Epub 2020 Feb 20.

Department of Radiotherapy and Radiation Oncology, Franziskus Hospital Bielefeld, Bielefeld, Germany.

Purpose: Breast cancer in men accounts for approximately 1% of all breast cancers. Breast cancer trials have routinely excluded men. The aim of this analysis was to determine the effect of different treatment factors, in particular, postoperative radiation therapy (RT) on long-term outcomes. Read More

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http://dx.doi.org/10.1016/j.adro.2020.01.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276673PMC
February 2020

Assessing and Providing Culturally Competent Care in Radiation Oncology for Deaf Cancer Patients.

Adv Radiat Oncol 2020 May-Jun;5(3):333-344. Epub 2020 Apr 13.

Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland.

Purpose: Recognition of disparities for vulnerable populations in the field of oncology is increasing, but little attention has been paid to deaf patients. At least a million Americans are culturally deaf and use American Sign Language. Poor linguistic and cultural competency among physicians is a barrier to care delivery for these patients, placing them at risk for treatment disparities. Read More

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http://dx.doi.org/10.1016/j.adro.2020.02.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276674PMC

Are Female Radiation Oncologists Still Underrepresented in the Published Literature? An Analysis of Authorship Trends During the Past Decade.

Adv Radiat Oncol 2020 May-Jun;5(3):325-332. Epub 2019 Sep 13.

Department of Radiation Oncology, London Health Sciences Centre, London, Ontario, Canada.

Purpose: We examined whether female authorship, traditionally underrepresented in the radiation oncology (RO) literature, has improved during the past decade, and whether the introduction of double-blind peer review (where reviewers are blinded to author names and vice-versa) improved female authorship rates.

Methods: We analyzed authorship lists during a 10-year period (2007-2016) from the 2 highest impact-factor RO journals: (IJROBP) and (R&O). From each journal, 20 articles per year were randomly selected. Read More

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http://dx.doi.org/10.1016/j.adro.2019.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276664PMC
September 2019

The Capital Investment Strategy for Radiation therapy in Ontario: A Framework to Ensure Access to Radiation Therapy.

Adv Radiat Oncol 2020 May-Jun;5(3):318-324. Epub 2019 Dec 31.

Radiation Treatment Program, Cancer Care Ontario, Canada.

Purpose: Ontario Health (Cancer Care Ontario), formerly known as CCO, is the provincial governmental agency in Ontario, Canada responsible for developing radiation therapy-specific capital investment strategies, updated every 5 years, to ensure equitable access and to gain the highest value from these investments in infrastructure. These plans are informed by the changing landscape of health care delivery, technologic advancements affecting radiation therapy care, patient desire for care closer to home, and expected increases in utilization of radiation therapy services. In this article, we describe the development, model, and final recommendations of CCO's fifth radiation therapy capital investment strategy. Read More

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http://dx.doi.org/10.1016/j.adro.2019.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280285PMC
December 2019

Do Women Have Equal Chances for an Academic Career in Radiation Oncology in Canada? A Comparison With Related Specialties.

Adv Radiat Oncol 2020 May-Jun;5(3):313-317. Epub 2019 Oct 16.

Department of Radiation Oncology Centre, Hospitalier de l'Université de Montréal (CHUM), Montreal, Canada.

Purpose: The progress of women in academic medicine appears to be curtailed. We evaluated gender differences in academia for residents in radiation oncology compared with 2 of its related specialties, radiology and medical oncology, across Canada.

Methods And Materials: We analyzed abstracts presented between 2013 and 2016 at the annual meetings of the Canadian Association of Radiation Oncologists and compared it to the corresponding data for the meetings of the Canadian Association of Radiologists and Canadian Association of Medical Oncology. Read More

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http://dx.doi.org/10.1016/j.adro.2019.09.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276660PMC
October 2019

ASTRO's Advances in Radiation Oncology Top Downloads of 2019.

Authors:
Robert C Miller

Adv Radiat Oncol 2020 May-Jun;5(3):311-312. Epub 2020 Mar 3.

Editor-in-Chief.

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http://dx.doi.org/10.1016/j.adro.2020.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276693PMC

Follow-up and management of head and neck cancer patients during the 2019 novel coronavirus (SARS-CoV-2) disease pandemic.

Adv Radiat Oncol 2020 May 15. Epub 2020 May 15.

Department of Human Oncology, UW Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health.

The SARS-CoV-2 pandemic has significantly impacted healthcare delivery around the world. Elective procedures and routine follow-ups have been cancelled and/or converted to tele-health visits by many systems. In this article, we focus on recommendations for the surveillance of head and neck cancer patients during and following radiotherapy treatment. Read More

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http://dx.doi.org/10.1016/j.adro.2020.04.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227497PMC

Clinical and Radiographic Presentations of COVID-19 among Patients Receiving Radiation Therapy for Thoracic Malignancies.

Adv Radiat Oncol 2020 May 11. Epub 2020 May 11.

MD Anderson Cancer Center, Department of Radiation Oncology, Houston, TX.

The 2019 novel coronavirus disease (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to a pandemic affecting healthcare centers across the globe. Patients with cancer have been reported to be particularly vulnerable to infection, morbidity, and severe events. Given the high proportion of asymptomatic carriers and concerns regarding speed and availability of laboratory testing, novel detection strategies are necessary to supplement traditional screening methods and facilitate mitigation of viral transmission. Read More

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http://dx.doi.org/10.1016/j.adro.2020.04.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212983PMC

Guidelines to Reduce Hospitalization Rates for Patients Receiving Curative-Intent Radiation Therapy During the COVID-19 Pandemic: Report from a Multicenter New York Area Institution.

Adv Radiat Oncol 2020 May 11. Epub 2020 May 11.

Department Radiation Medicine, Northwell Health Cancer Institute, Lake Success, New York.

As the COVID-19 pandemic spreads around the globe, access to radiation therapy remains critical for cancer patients. The priority for all radiation oncology departments is to protect the staff and to maintain operations in providing access to those patients requiring radiation therapy services. Patients with tumors of the aerodigestive tract and pelvis amongst others often experience toxicity during treatment, and there is a baseline risk that adverse effects may require hospital-based management. Read More

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http://dx.doi.org/10.1016/j.adro.2020.04.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212958PMC

Effectiveness of CBCT imaging during radiotherapy for the detection of initial COVID-19 lung disease.

Adv Radiat Oncol 2020 May 8. Epub 2020 May 8.

Medical Physics Department, Veneto Institute of Oncology IOV - IRCCS, Padua, Italy.

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http://dx.doi.org/10.1016/j.adro.2020.04.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7207168PMC

Long-term Institutional Experience with Telemedicine Services for Radiation Oncology: A Potential Model for Long-term Utilization.

Adv Radiat Oncol 2020 May 8. Epub 2020 May 8.

Department of Radiation Oncology, the University of Texas MD Anderson Cancer Center, Houston, Texas.

With the development of the COVID-19 pandemic, healthcare practices and radiation oncology departments have begun to incorporate telemedicine services to practice social distancing and minimize the chances of disease spread. Given the severity of this pandemic, it will likely fundamentally impact the use of these services for years to come. Our institution and radiation oncology department have used telemedicine services for many years; we would like to report on our departmental experience to guide other radiation oncology practices on its long-term use for clinical evaluation and patient care. Read More

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http://dx.doi.org/10.1016/j.adro.2020.04.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205717PMC

Need for Caution in the Diagnosis of Radiation Pneumonitis in the COVID-19 Pandemic.

Adv Radiat Oncol 2020 May 5. Epub 2020 May 5.

Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center NYC, NY.

Introduction: Patients with cancer are at high-risk for mortality from coronavirus-disease 2019 (COVID-19). Radiation pneumonitis (RP) is a common toxicity of thoracic radiotherapy with overlapping clinical and imaging features with COVID-19, however, RP is treated with high-dose corticosteroids, which may exacerbate COVID-19-associated lung injury. We reviewed patients who presented with symptoms of RP during the intensification of a regional COVID-19 epidemic to report on their clinical course and COVID-19 testing results. Read More

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http://dx.doi.org/10.1016/j.adro.2020.04.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199721PMC

Experiencing the Surge: Report from a Large New York Radiation Oncology Department During the COVID-19 Pandemic.

Adv Radiat Oncol 2020 May 5. Epub 2020 May 5.

Department of Radiation Oncology at the Icahn School of Medicine at Mount Sinai, New York, NY.

Purpose/Objective(s): The COVID-19 pandemic is impacting all aspects of life and changing the practice of medicine. Multiple recommendations exist on how radiation oncology practices should deal with this crisis, but little information is available on what actually happens when the COVID-19 surge arrives. New York City experienced the first surge of COVID-19 in the United States and is now the epicenter of the global pandemic. Read More

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http://dx.doi.org/10.1016/j.adro.2020.04.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199705PMC

Contingency Plans in a Radiation Oncology Department Amid the 2019-nCoV Outbreak in Switzerland.

Adv Radiat Oncol 2020 Mar 31. Epub 2020 Mar 31.

Department of Radiation Oncology, University Hospital Basel, Basel, Switzerland.

The ongoing novel coronavirus (2019-nCoV) pandemic is expected to develop into an unprecedented stress test for health care systems worldwide. This brief report, written from a radiation oncology perspective during the developing outbreak of 2019-nCoV in Switzerland, highlights the challenges identified and measures taken in our department to mitigate risks and ensure continued operations during the outbreak. Read More

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http://dx.doi.org/10.1016/j.adro.2020.03.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195454PMC

Experience of a Radiation Oncology Center Operating During the COVID-19 Outbreak.

Authors:
Jiade J Lu

Adv Radiat Oncol 2020 Apr 10. Epub 2020 Apr 10.

Shanghai Proton and Heavy Ion Center, Shanghai, China.

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http://dx.doi.org/10.1016/j.adro.2020.04.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195375PMC

New policy and regulation for a Radiology-Oncology Center at the time of Covid-19 outbreak in Tehran-Iran.

Adv Radiat Oncol 2020 Apr 14. Epub 2020 Apr 14.

Associate Professor of Radiology, Pardis Noor Radiology-Oncology Centre, Radiology group.

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http://dx.doi.org/10.1016/j.adro.2020.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195356PMC

A call for new 4R's based Radiation Oncology model in COVID-19 Pandemic.

Adv Radiat Oncol 2020 Apr 25. Epub 2020 Apr 25.

CancerCare Manitoba and University of Manitoba, Winnipeg, Manitoba, Canada.

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http://dx.doi.org/10.1016/j.adro.2020.04.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195347PMC

Efforts to Reduce the Impacts of COVID-19 Outbreak on Radiation Oncology in Taiwan.

Adv Radiat Oncol 2020 Apr 6. Epub 2020 Apr 6.

Division of Radiation Oncology, Department of Oncology, National Taiwan University Hospital.

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http://dx.doi.org/10.1016/j.adro.2020.03.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195280PMC

Palliative Radiotherapy for Oncologic Emergencies in the setting of COVID-19: Approaches to Balancing Risks and Benefits.

Adv Radiat Oncol 2020 Apr 8. Epub 2020 Apr 8.

PROMISE (Precision Radiation for OligoMetastatIc and MetaStatic DiseasE) Program, Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center.

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http://dx.doi.org/10.1016/j.adro.2020.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194647PMC

Implementation of a Novel Remote Physician SBRT Coverage Process during the Coronavirus Pandemic.

Adv Radiat Oncol 2020 Apr 28. Epub 2020 Apr 28.

Department of Radiation Oncology, Washington University in St Louis School of Medicine.

Introduction: During the COVID-19 pandemic, alternative methods of care are needed to reduce the relative risk of transmission in departments. Also needed is the ability to provide vital radiation oncological care if radiation oncologists (RO) are reallocated to other departments. We implemented a novel remote RO SBRT coverage practice, requiring it to be reliable, of high audio and visual quality, timely, and the same level of specialty care as our current in-person treatment coverage practice. Read More

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http://dx.doi.org/10.1016/j.adro.2020.04.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186133PMC

Departments of Radiation Oncology Must Prepare for COVID-19 Outbreak.

Adv Radiat Oncol 2020 Apr 25. Epub 2020 Apr 25.

Department of Radiation Oncology, Yeungnam University College of Medicine, 170, Hyeonchung-ro, Nam-gu, Daegu 42415, South Korea.

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http://dx.doi.org/10.1016/j.adro.2020.03.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182742PMC

Practice considerations for proton beam radiotherapy of uveal melanoma during the COVID-19 pandemic: PTCOG Ocular experience.

Adv Radiat Oncol 2020 Apr 23. Epub 2020 Apr 23.

Nuffield Laboratory of Ophthalmology, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom.

Uveal melanoma (UM) is a rare but life-threatening cancer of the eye. In light of the COVID-19 pandemic, hospitals and proton eye therapy facilities must analyze several factors to ensure appropriate treatment protocols for patients and provider teams. Practice considerations to limit COVID-19 transmission in the proton ocular treatment setting for UM are necessary. Read More

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http://dx.doi.org/10.1016/j.adro.2020.04.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179507PMC

Management of Locally Advanced Rectal Cancer During The COVID-19 Pandemic: A Necessary Paradigm Change at Memorial Sloan Kettering Cancer Center.

Adv Radiat Oncol 2020 Apr 22. Epub 2020 Apr 22.

Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY.

The COVID-19 pandemic will consume significant health care resources. Given concerns for rapidly rising infection rates in the US, impending staffing shortages, and potential for resource re-allocation, we rapidly re-evaluated our rectal cancer practice polices during this public health emergency. Previous to the pandemic we commonly utilized total neoadjuvant therapy (TNT) with a strong preference for long course chemoradiation (LCCRT). Read More

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http://dx.doi.org/10.1016/j.adro.2020.04.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175910PMC