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Adv Urol 2020 18;2020:6063018. Epub 2020 Jun 18.

Dniprovsky Regional Clinical Oncology Dispensary, Dnipro 49055, Ukraine.

Objectives: To assess the outcomes of cavoatrial tumor thrombus removal using the liver transplantation technique for thrombectomy, a retrospective study was conducted.

Materials And Methods: Five patients with atrial tumor thrombi who underwent piggy-back mobilization of the liver, surgical access to the right atrium from the abdominal cavity, and external manual repositioning of the thrombus apex below the diaphragm (milking maneuver) were included into the study. Extracorporeal circulation was used in none of the cases. Read More

Adv Urol 2020 26;2020:9191830. Epub 2020 May 26.

Institute for Urology and Reproductive Health, Moscow, Russia.

This study aimed to report the learning curve in robot-assisted radical prostatectomy (RARP) performed by one surgeon who is experienced in laparoscopic prostatectomies. The records of 145 RARP cases performed between 2015 and 2017 were evaluated retrospectively. Patients were divided into three groups: group 1 comprised the first 49 cases, group 2 comprised 50-88 cases, and the rest of the cases were assigned to group 3. Read More

Adv Urol 2020 29;2020:4347598. Epub 2020 Jan 29.

Department of Urology and Kidney Transplant Surgery, Tribhuvan University Teaching Hospital, Institute of Medicine, Maharajgung, Kathmandu 44600, Nepal.

Introduction: Urolithiasis is one of the common disorder with which about 1/5 is found in the ureter, of which 2/3 is seen in the lower ureter. Medical expulsive therapy is one of the routine modalities of treatment which uses various drugs acting on the ureter smooth muscle by different mechanism. We aim to compare the efficacy of combination vs. Read More

Adv Urol 2020 27;2020:3842680. Epub 2020 Apr 27.

Indiana University School of Medicine, Department of Urology, 1801 Senate Blvd. Suite 220, Indianapolis, IN 46202, USA.

Methods: A female pig was placed under general anesthesia and positioned supine, and retrograde access to the renal collecting system was obtained. The LithoVue (Boston Scientific) and Uscope (Pusen Medical) were evaluated by three experienced surgeons, and each surgeon started with a new scope. The following parameters were compared between each ureteroscope: time for navigation to upper and lower pole calyces with and without implements (1. Read More

Adv Urol 2020 13;2020:6325490. Epub 2020 Jan 13.

Université Saint Joseph, Faculty of Medicine, Beirut, Lebanon.

Phytotherapy for lower urinary tract symptoms (LUTSs) due to benign prostate hyperplasia (BPH) is progressively demanded by patients and trusted by physicians. The aim was to assess the efficacy of a mix of pumpkin seed extract, soy germ isoflavonoids, and cranberry (Novex®) in the management of mild to moderate LUTS in BPH patients. Male patients aged ≥40 years, who had had mild to moderate LUTS for >6 months at screening, with no previous therapy or who are still symptomatic despite current use of alpha-blockers, were recruited. Read More

Adv Urol 2020 18;2020:9068068. Epub 2020 Feb 18.

Department of Urology, University of Texas Health San Antonio, San Antonio, TX, USA.

Objective: To perform a proof of concept microbiome evaluation and PD-L1 expression profiling in clear-cell renal cell carcinoma (cc-RCC) with associated tumor thrombus (TT).

Methods: After IRB approval, six patients underwent radical nephrectomy (RN) with venous tumor thrombectomy (VTT). We collected fresh tissue specimens from normal adjacent, tumor, and thrombus tissues. Read More

Adv Urol 2019 12;2019:2614586. Epub 2019 Dec 12.

West Virginia University Hospitals, Department of Urology, Morgantown, USA.

Bladder rupture occurs in only 1.6% of blunt abdominopelvic trauma cases. Although rare, bladder rupture can result in significant morbidity if undiagnosed or inappropriately managed. Read More

Adv Urol 2019 17;2019:3679493. Epub 2019 Oct 17.

Cleveland Clinic, Glickman Urological & Kidney Institute, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

Introduction: Both elevated testosterone and polycystic ovary syndrome (PCOS) have been speculated as possible risk factors for kidney stone formation; however, the details of this potential relationship with regards to 24-hour urine metabolic panels and stone composition have not previously been characterized.

Methods: A total of 74 PCOS patients were retrospectively identified and matched with a cohort of female stone formers at a 3 : 1 ratio (by age and BMI). All patients had 24-hour urinary metabolic panels and stone compositions. Read More

Adv Urol 2019 25;2019:3031609. Epub 2019 Sep 25.

Department of Biomedical Sciences, School of Allied Health Sciences, University of Cape Coast, Cape Coast, Ghana.

Background: Benign prostatic hyperplasia (BPH) is a common urological disorder reported among ageing men.

Objective: The study assessed histoprotective effect of lime essential oil (LEO) in a rat model of testosterone-induced benign prostatic hyperplasia (BPH) and evaluated its ability to reverse testosterone-mediated changes in the testis, kidney, and liver.

Materials And Methods: Adult Sprague Dawley (aged 12 weeks, 240-390 g) male rats were intramuscularly injected with testosterone enanthate (TE) (10 mg/kg) reconstituted in olive oil for ten days to establish benign prostatic hyperplasia (serum PSA level ≥ 1. Read More

Adv Urol 2019 22;2019:6214921. Epub 2019 Aug 22.

Clinical Research Group, Boston Medical Group, Bogotá 110111, Colombia.

Priapism may present as a side effect in patients treated with medications for erectile dysfunction, in which it should be controlled in a timely manner to avoid complications. There is little information regarding the use of local measures for the treatment of this condition. This study was done with the objective to describe the management of priapism secondary to erectile dysfunction drugs in a cohort of men. Read More

Adv Urol 2019 23;2019:3590623. Epub 2019 Apr 23.

University of Texas Health San Antonio, Department of Urology, San Antonio, TX, USA.

Objective: To develop software to assess the potential aggressiveness of an incidentally detected renal mass using images.

Methods: Thirty randomly selected patients who underwent nephrectomy for renal cell carcinoma (RCC) had their images independently reviewed by engineers. Tumor "Roughness" was based on image algorithm of tumor topographic features visualized on computed tomography (CT) scans. Read More

Adv Urol 2019 2;2019:2757862. Epub 2019 Apr 2.

Independent Medical Consultant, MD, MedDevHealth, Copenhagen, Denmark.

A risk factor model for urinary tract infections in patients with adult neurogenic lower urinary tract dysfunction performing clean intermittent catheterisation was developed; it consists of four domains, namely, (1) general (systemic) conditions in the patient, (2) individual urinary tract conditions in the patient, (3) routine aspects related to the patient, and (4) factors related to intermittent catheters . The conceptual model primarily concerns patients with spinal cord injury, spina bifida, multiple sclerosis, or cauda equina where intermittent catheterisation is a normal part of the bladder management. On basis of several literature searches and author consensus in case of lacking evidence, the model intends to provide an overview of the risk factors involved in urinary tract infections, with specific emphasis to describe those that in daily practice can be handled and modified by the clinician and so come to the benefit of the individual catheter user in terms of fewer urinary tract infections. Read More

Adv Urol 2019 20;2019:2468926. Epub 2019 Mar 20.

Department of Urology, Sir Ganga Ram Hospital, New Delhi, India.

Testosterone deficiency syndrome (TDS) is a gradual age-related phenomenon that occurs in a large proportion of the aging male population. This current prospective study was done with the objective to estimate the prevalence of age-associated TDS in India and its clinical profile. A total of 800 male patients aged ≥40 year were approached to participate in the study. Read More

Adv Urol 2019 7;2019:5794957. Epub 2019 Mar 7.

University of Texas Health San Antonio, Department of Urology, San Antonio, USA.

Background: The aim of this study was to investigate the effectiveness of surgical simulators created using household items and to determine their potential role in surgical skills training.

Methods: Ten urology residents attended a surgical skills workshop and practiced using surgical simulators and models. These included a wound closure model, an open prostatectomy model, a delicate tissue simulation, a knot-tying station, and a laparoscopic simulator. Read More

Adv Urol 2019 17;2019:6287057. Epub 2019 Jan 17.

Lycotec Ltd., Granta Park, Cambridge CB21 6GP, UK.

In the present paper, we report that can be efficiently propagated and affect mRNA expression for two major cytokines, relevant to tumor progression, in CWR-R1 cells, a malignant prostate cell line. CWR-R1 and McCoy cells, a classic cell line for chlamydial research, were grown and infected with under similar conditions. Cell monolayers were harvested for RNA analysis and immunostaining with major outer membrane protein (MOMP) antibody at 24, 48, and 72 hours of the postinfection (hpi) period. Read More

Adv Urol 2018 26;2018:1525832. Epub 2018 Dec 26.

Department of Orthopaedics, Animus-Kyanous Hospital, Larisa, Greece.

Purpose: Prostate cancer (PCa) is one of the most frequently diagnosed malignancies worldwide. Hormonal deprivation therapy is a well-established treatment for locally advanced or metastatic diseases but exposes patients to the risk of osteoporosis and fragility fractures. Furthermore, the tropism of the PCa cells to osseous metastases increases the incidence of skeletal-related events (SREs). Read More

Adv Urol 2018 24;2018:8124325. Epub 2018 Dec 24.

Biology Department, Science Faculty, Gazi University, 06500 Ankara, Turkey.

Oxybutynin is an important anticholinergic agent that prevents uncontrolled contractions in the treatment of overactive bladder (OAB). However, drugs containing oxybutynin have significant side effects such as dry eyes, dry mouth, increased heart rate, constipation, blurred vision, and confusion. In recent years, new delivery methods for this agent are being searched. Read More

Adv Urol 2018 29;2018:9738548. Epub 2018 Nov 29.

Department of Urology, University College Hospital Galway, Newcastle Road, Galway, Ireland.

Background: A combined urology clinic staffed by four consultants and four non-consultant hospital doctors (NCHDs) was introduced in our institution in October 2015. This clinic is supported by a pre-clinic radiology meeting and a synchronous urology clinical nurse specialist (CNS) clinic with protected uroflow/trial of void slots. Herein, we report on the outcomes of this clinic in comparison with the standard format of urology outpatient review. Read More

Adv Urol 2018 9;2018:8727301. Epub 2018 Dec 9.

Columbia University Division of Urology, Mount Sinai Medical Center, Miami Beach 33140, FL, USA.

Surgical site infection rates remain a common postoperative problem that continues to affect patients undergoing urologic surgery. Our study seeks to evaluate the difference in surgical site infection rates in patients undergoing open radical cystectomy when comparing the Bookwalter vs. the Alexis wound retractors. Read More

Adv Urol 2018 4;2018:6705152. Epub 2018 Dec 4.

Department of Urology, Austin Hospital, VIC, Australia.

Introduction: To compare (1) the quality of prostate cancer health information on the Internet, (2) the difference in quality between websites appearing earlier or later in the search, and (3) the sources of sponsorship for each of these websites.

Materials And Methods: The top 150 listed websites on the Google search engine for each of the 11 search terms related to prostate cancer were analysed. Quality was assessed on whether the website conforms to the principles of the Health On the Net Foundation. Read More

Adv Urol 2018 21;2018:9137892. Epub 2018 Nov 21.

Kulkarni Reconstructive Urology Center, Pune, India.

Introduction And Objective: The proper evaluation of urethral strictures is an essential part of the surgical planning in urethral reconstruction. The proper evaluation of the stricture can be challenging in certain situations, especially when the meatus is involved. We propose that the use of a small caliber ureteroscope (4. Read More

Adv Urol 2018 29;2018:9073807. Epub 2018 Oct 29.

Urogenital Research Unit, State University of Rio de Janeiro (UERJ), Rio de Janeiro-RJ, Brazil.

Objective: To assess the learning curve in robot-assisted radical prostatectomy (RARP) performed by surgeons without previous experience in laparoscopic prostatectomy.

Materials And Methods: We analyzed 119 patients submitted to RARP performed by two surgeons without previous experience in laparoscopic prostatectomy, with emphasis on the relevant outcomes such as continence, erectile function, and oncologic control with a minimum follow-up of 24 months. We used Fisher's exact test and the chi-square test to investigate the existence of a relationship between the variables and analysis of variance (ANOVA) to verify possible statistically significant differences between groups, at the 5% level. Read More

Adv Urol 2018 24;2018:1620470. Epub 2018 Oct 24.

MS General Surgery, Consultant Surgeon, GMC-Jammu, Jammu and Kashmir, India.

Background: Cryptorchidism or undescended testes is the most common disorder of the male endocrine glands in children. With the advancements in laparoscopic techniques and instruments, laparoscopic orchidopexy has become the standard procedure in the management of nonpalpable undescended testes.

Aim: To evaluate and determine the therapeutic role, sensitivity, and specificity of laparoscopy in localizing nonpalpable testes and the mean operative time, the conversion rate (and reasons thereof), postoperative wound infection, postoperative stay, and time taken for return to daily activities following laparoscopic orchidopexy or orchidectomy. Read More

Adv Urol 2018 21;2018:4948165. Epub 2018 Oct 21.

Urology Resident in Kermanshah University of Medical Sciences, Kermanshah, Iran.

Introduction: Vesicoureteral reflux (VUR) is a common urologic anomaly in children. Many techniques have been offered to manage this condition, in which one of them is modified Gil-Vernet antireflux surgery. The study fullfiled to evaluate the efficacy and safety of modified Gil-Vernet antireflux surgery in correction of high-grade VUR. Read More

Adv Urol 2018 19;2018:4821084. Epub 2018 Aug 19.

Department of Urology, Indiana University Medical Center, Indianapolis, IN, USA.

Adv Urol 2018 29;2018:6782736. Epub 2018 Jul 29.

Department of Urology, Hospital Universitario de Valme, Ctra. de Cádiz Km. 548.9, 41014 Seville, Spain.

Objectives: Evaluation of changes in symptoms among patients with overactive bladder syndrome treated with transdermal oxybutynin and tolerability after 12 months of follow-up.

Methods: This was a multicenter, retrospective, single-cohort, observational study. Changes in symptoms were evaluated primarily with a 3-day voiding diary. Read More

Adv Urol 2018 24;2018:5056049. Epub 2018 Apr 24.

Department of Reproductive Health, Moi University School of Medicine, P.O. Box 3900-30100, Eldoret, Kenya.

Background: Ureteric pathology arises from surgical misadventures, trauma, and congenital anomalies. Early detection and treatment is of the essence.

Objectives: To determine the types/etiology and outcome of ureteric pathology presenting to Gynocare Fistula Centre, Eldoret, Kenya. Read More

Adv Urol 2018 3;2018:2146080. Epub 2018 May 3.

Department of Urology, James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Objectives: The robotic-assisted laparoscopic retroperitoneal lymph node dissection (R-RPLND) represents a new frontier in the surgical management of testicular cancer in the realm of minimally invasive urologic oncology. We aimed to review the early outcomes as compared to the laparoscopic and open approaches as well as describe the operative technique for the R-RPLND.

Materials And Methods: We reviewed all the literature related to the R-RPLND based on an electronic PubMed search up until July 2017. Read More

Adv Urol 2018 5;2018:6783147. Epub 2018 Apr 5.

Department of Urology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.

The surgical management of both early and advanced stage germ cell tumors of the testis remains a complex process of surgical decision making to maximize oncologic control while minimizing morbidity. Over the past 5 decades, the evolution of the surgical template for retroperitoneal lymphadenectomy (RPLND) has resulted in important modifications to achieve these goals. In this review, we will characterize the historical motivating factors that led to the modified template, outline patient and clinical factors in selecting these approaches in both early and advanced stage disease, and briefly discuss future horizons for their implementation. Read More

Adv Urol 2018 2;2018:8781698. Epub 2018 Apr 2.

Institute of Cancer Research and Royal Marsden Hospital FT, Sutton, Surrey, UK.

Testicular germ cell tumours are the commonest tumours of young men and are broadly managed either as pure seminomas or as 'nonseminomas'. The management of Stage 1 nonseminomatous germ cell tumours (NSGCTs), beyond surgical removal of the primary tumour at orchidectomy, is somewhat controversial. Cancer-specific survival rates in these patients are in the order of 99% regardless of whether surveillance, retroperitoneal lymph node dissection, or adjuvant chemotherapy is employed. Read More

Adv Urol 2018 26;2018:7031906. Epub 2018 Mar 26.

Division of Pediatric Urology, Department of Urology, Medical College of Wisconsin, Children's Hospital of Wisconsin, Milwaukee, WI, USA.

Purpose: To evaluate the impact of prophylactic antibiotics after distal hypospadias repair on postoperative bacteriuria, symptomatic urinary tract infection, and postoperative complications in a prospective, randomized trial.

Materials And Methods: Consecutive patients aged 6 months to 2 years were enrolled at our institution between June 2013 and May 2017. Consenting patients were randomized to antibiotic prophylaxis with trimethoprim-sulfamethoxazole versus no antibiotic. Read More

Adv Urol 2018 26;2018:3404587. Epub 2018 Mar 26.

Department of Urology, Hotel-Dieu de France University Hospital, Boulevard Alfred Naccache, Achrafieh, P.O. Box 166830, Beirut, Lebanon.

Introduction And Objectives: Renal autotransplantation is a kidney-saving surgical procedure used in selected patients. The purpose of this report is to review nine typical and atypical indications for kidney autotransplantation and evaluate its effectiveness in maintaining kidney function and avoiding cancer recurrence.

Materials And Methods: From 1999 till 2014, nine renal autotransplantations were performed in our center. Read More

Adv Urol 2018 15;2018:7272541. Epub 2018 Mar 15.

Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

The majority of metastatic germ cell tumors (GCTs) are cured with cisplatin-based chemotherapy, but 20-30% of patients will relapse after first-line chemotherapy and require additional salvage strategies. The two major salvage approaches in this scenario are high-dose chemotherapy (HDCT) with autologous stem cell transplant (ASCT) or conventional-dose chemotherapy (CDCT). Both CDCT and HDCT have curative potential in the management of relapsed/refractory GCT. Read More

Adv Urol 2018 13;2018:3718165. Epub 2018 Mar 13.

2nd Department of Oncology, Faculty of Medicine, Comenius University, National Cancer Institute, Bratislava, Slovakia.

Germ-cell tumors (GCTs) are highly curable with chemotherapy. Salvage chemotherapy or surgery can cure a proportion of patients, but the ones failing these treatments will die of their disease in the young age. Immune checkpoint pathways are emerging as powerful targetable biomarkers, and a significant preclinical and clinical research is underway to widen our knowledge and expand the treatment possibilities with immune therapy. Read More

Adv Urol 2018 13;2018:3453808. Epub 2018 Mar 13.

University of Maryland School of Medicine, Baltimore, MD, USA.

We investigated gender differences in the histopathologic presentation of bladder cancer cases in Egypt, where both urothelial cell carcinoma (UC) and squamous cell carcinoma (SCC) types are highly prevalent. We used logistic regression to estimate the unadjusted (OR) and adjusted odds ratio (AOR) and 95% confidence interval (CI) of the associations between gender and different histopathologic and sociodemographic parameters of 2,186 confirmed cases of primary bladder cancer (1,775 males and 411 females; 784 SCC and 1,402 UC). There were no statistically significant gender differences in tumor grade, stage, mucosal ulcer, or inflammatory cystitis, regardless of the cancer type, but men were less likely than women to have undergone cystectomy with pelvic lymphadenectomy. Read More

Adv Urol 2018 11;2018:7193843. Epub 2018 Mar 11.

Department of Urology, University of Cagliari, Via Is Mirrionis 92, 09121 Cagliari, Italy.

Background: At present, the percutaneous nephrolithotripsy (PCNL) is performed both in supine and in prone position. The aim of this paper is to describe an innovative position during PCNL.

Methods: We describe a supine position. Read More

Adv Urol 2018 18;2018:8671832. Epub 2018 Feb 18.

Melvin and Bren Simon Cancer Center, Indiana University, Indianapolis, IN, USA.

Testicular cancer has become the paradigm of adult-onset cancer survivorship, due to the young age at diagnosis and 10-year relative survival of 95%. This clinical review presents the current status of various treatment-related complications experienced by long-term testicular cancer survivors (TCS) free of disease for 5 or more years after primary treatment. Cardiovascular disease and second malignant neoplasms represent the most common potentially life-threatening late effects. Read More

Adv Urol 2018 19;2018:7182014. Epub 2018 Feb 19.

Division of Urology, Departments of Surgery and Surgical Oncology, Princess Margaret Cancer Centre, University Health Network and the University of Toronto, Toronto, ON, Canada.

Testicular cancer is the most common malignancy in young men, and the incidence is increasing in most countries worldwide. The vast majority of patients present with clinical stage I disease, and surveillance is being increasingly adopted as the preferred management strategy. At the time of diagnosis, patients on surveillance are often counselled about their risk of relapse based on risk factors present at diagnosis, but this risk estimate becomes less informative in patients that have survived a period of time without experiencing relapse. Read More

Adv Urol 2018 18;2018:1846060. Epub 2018 Feb 18.

IASO General Hospital, Athens, Greece.

Purpose: To present a modified technique of managing extensive penile urethral strictures with dorsal and ventral onlay buccal mucosa grafts.

Patients And Methods: From October 2014 to January 2016, a total of 12 patients underwent urethroplasty for penile urethral strictures, using dorsal and ventral onlay grafts from buccal mucosa. The mean age was 42. Read More

Adv Urol 2018 31;2018:2375176. Epub 2018 Jan 31.

Department of Surgery, Division of Urology, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO, USA.

While testicular germ cell tumors (T-GCTs) make up only 0.5% of pediatric malignancies and less than 2% of adult malignancies, they comprise 14% of adolescent malignancies, making it the most common solid tumor in this age group. The transition in incidence at this age is also accompanied by a transition in tumor histology with adolescents having mostly pure embryonal carcinoma and mixed nonseminomatous germ cell tumors. Read More

Adv Urol 2017 21;2017:5674237. Epub 2017 Dec 21.

Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Mansoura University, Mansoura, Egypt.

Background: Fractalkine is produced in seminal plasma in small amounts and correlates with sperm motility.

Purpose: To investigate the possible effect of low-level leucospermia on spermatozoa oxidative stress and sDNA fragmentation in patients with subclinical varicocele and apparently normal seminogram, and also to study the role of spermatozoal fractalkine and its receptor (CX3CR1) gene expression as a marker of spermatozoa inflammatory response.

Methods: This study included 80 patients with subclinical varicocele (45 fertile and 35 infertile) and 45 age-matched fertile volunteers. Read More

Adv Urol 2018 4;2018:9059382. Epub 2018 Feb 4.

Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Germ cell tumors (GCTs) arising in infants, children, and adolescents present a set of special challenges. GCTs make up about 3% of malignancies in children aged 0-18 and nearly 15% of cancers in adolescents. Epidemiologic and molecular evidence suggests that GCTs in young children likely represent a distinct biologic group as compared to GCTs of older adolescents and adults. Read More

Adv Urol 2018 4;2018:3068365. Epub 2018 Feb 4.

Department of Microbial, Cellular and Molecular Biology, College of Natural Sciences, Addis Ababa University, P.O. Box 1176, Addis Ababa, Ethiopia.

Kidney stone disease is a crystal concretion formed usually within the kidneys. It is an increasing urological disorder of human health, affecting about 12% of the world population. It has been associated with an increased risk of end-stage renal failure. Read More

Adv Urol 2018 1;2018:7978958. Epub 2018 Feb 1.

University of Southern California Institute of Urology, 1441 Eastlake Avenue, Los Angeles, CA 90033, USA.

Reducing the long-term morbidity in testicular cancer survivors represents a major area of interest. External beam radiation therapy and systemic chemotherapy are established treatments for seminoma; however, they are associated with late toxicities such as cardiovascular disease, insulin resistance, and secondary malignancy. Retroperitoneal lymph node dissection (RPLND) is a standard treatment for nonseminomatous germ cell tumors (NSGCT) that has minimal long-term morbidity. Read More

Adv Urol 2017 21;2017:1843687. Epub 2017 Dec 21.

Universidad Nacional de Colombia, Cra. 45 No. 26-85, Bogotá, Colombia.

Objective: The aim of this study is to evaluate the response to low-intensity extracorporeal shock wave therapy in a group of patients with organic vascular erectile dysfunction.

Materials And Methods: This is an observational retrospective study. The researchers reviewed 710 patients with a clinical diagnosis of organic vascular erectile dysfunction (ED) of more than 3-month duration from male sexual health clinics of the Boston Medical Group from 12 cities in Spain and 4 in Mexico. Read More

Adv Urol 2017 4;2017:4653512. Epub 2017 Jul 4.

Department of Urology, Andrology Center, San Matteo Hospital, Pavia, Italy.

Peyronie's disease (PD) is a chronic inflammation of tunica albuginea of the corpora cavernosa that causes an inelastic plaque resulting in penis deformation. Although its etiology is not completely known, there is general consensus that PD is genetically transmitted and secondary to penile trauma. In recent years, numerous studies demonstrated the role played by oxidative stress in PD pathogenesis, and other studies have described successful use of antioxidants in PD treatment. Read More

Adv Urol 2017 13;2017:4842025. Epub 2017 Jun 13.

Department of Urology, Sapporo Medical University School of Medicine, Sapporo, Japan.

Objectives: The persistence of silodosin and the reasons for withdrawal from treatment of previously untreated Japanese patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia (LUTS/BPH) were evaluated in real-life clinical practice.

Methods: A total of 81 previously untreated Japanese patients diagnosed with LUTS/BPH were treated with silodosin monotherapy and prospectively followed for 4 years. The persistence rate was estimated using the Kaplan-Meier method. Read More

Adv Urol 2017 28;2017:1404610. Epub 2017 May 28.

Department of Nephro-Urology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.

Objectives: Primary mediastinal germ cell tumors (PMGCTs) are rare, which often makes them difficult to treat. Herein, we examined patients with PMGCTs who underwent multimodal treatment.

Methods: We examined 6 patients (median age: 25 years, range: 19-27 years) with PMGCTs who underwent multimodal treatment between April 2001 and March 2015. Read More

Adv Urol 2017 21;2017:3254980. Epub 2017 May 21.

Urogenital Research Unit, State University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.

Purpose: To compare the structure of the testis in fetuses with prune belly syndrome (PBS) to normal controls.

Materials And Methods: We studied 6 testes obtained from 3 fetuses with PBS and 14 testes from 7 male fetuses. The testicular specimens were cut into 5-m thick sections and stained with hematoxylin and eosin (HE), to observe the seminiferous tubules; Weigert's solution to observe elastic fibers; and picrosirius red to observe collagen. Read More

Adv Urol 2017 11;2017:3197869. Epub 2017 Apr 11.

Lerner College of Medicine, Education Institute, Cleveland Clinic, Cleveland, OH, USA.

. To determine if routine preoperative and intraoperative urine cultures (UCx) are necessary in pediatric vesicoureteral (VUR) reflux surgery by identifying their association with each other, preoperative symptoms, and surgical outcomes. . Read More