Adv Phys Org Chem 2016 ;50:119-202
Johns Hopkins University, Baltimore, MD, United States.
Nucleic acid oxidation plays a vital role in the etiology and treatment of diseases, as well as aging. Reagents that oxidize nucleic acids are also useful probes of the biopolymers' structure and folding. Radiation scientists have contributed greatly to our understanding of nucleic acid oxidation using a variety of techniques. Read More