3 results match your criteria Advances In Inorganic Chemistry[Journal]

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Photodynamic inactivation (PDI) as a promising alternative to current pharmaceuticals for the treatment of resistant microorganisms.

Adv Inorg Chem 2022 25;79:65-103. Epub 2022 Jan 25.

Faculty of Chemistry, Jagiellonian University, Kraków, Poland.

Although the whole world is currently observing the global battle against COVID-19, it should not be underestimated that in the next 30 years, approximately 10 million people per year could be exposed to infections caused by multi-drug resistant bacteria. As new antibiotics come under pressure from unpredictable resistance patterns and relegation to last-line therapy, immediate action is needed to establish a radically different approach to countering resistant microorganisms. Among the most widely explored alternative methods for combating bacterial infections are metal complexes and nanoparticles, often in combination with light, but strategies using monoclonal antibodies and bacteriophages are increasingly gaining acceptance. Read More

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January 2022

Opportunities and challenges for metal chemistry in molecular imaging: from gamma camera imaging to PET and multimodality imaging.

Adv Inorg Chem 2016 16;68:1-41. Epub 2015 Nov 16.

King's College London, Division of Imaging Sciences and Biomedical Engineering, St Thomas' Hospital, London, UK.

The development of medical imaging is a highly multidisciplinary endeavor requiring the close cooperation of clinicians, physicists, engineers, biologists and chemists to identify capabilities, conceive challenges and solutions and apply them in the clinic. The chemistry described in this article illustrates how synergistic advances in these areas drive the technology and its applications forward, with each discipline producing innovations that in turn drive innovations in the others. The main thread running through the article is the shift from single photon radionuclide imaging towards PET, and in turn the emerging shift from PET/CT towards PET/MRI and further, combination of these with optical imaging. Read More

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November 2015

Controlling Platinum, Ruthenium and Osmium Reactivity for Anticancer Drug Design.

Adv Inorg Chem 2009 Jul;61:1-62

Department of Chemistry, University of Warwick, Coventry CV4 7AL, United Kingdom.

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