1,193 results match your criteria Advances In Clinical And Experimental Medicine[Journal]


Dietary curcumin and capsaicin: Relationship with hepatic oxidative stress and apoptosis in rats fed a high fat diet.

Adv Clin Exp Med 2019 Apr 15. Epub 2019 Apr 15.

Department of Biochemistry, Istanbul Faculty of Medicine, Istanbul University, Turkey.

Background: Apoptosis plays a major role in fatty liver disease. High-fat diets are related to the onset of fatty liver disease and hepatic oxidant-antioxidant imbalance. Curcumin and capsaicin are somewhat beneficial in reducing hepatic triglycerides; this is most likely because they are known to downregulate reactive oxygen species (ROS) and apoptosis. Read More

View Article

Download full-text PDF

Source
http://www.advances.umed.wroc.pl/ahead-of-print/94145.pdf
Publisher Site
http://dx.doi.org/10.17219/acem/94145DOI Listing
April 2019
1 Read

Complications in cardiac surgery: An analysis of factors contributing to sternal dehiscence in patients who underwent surgery between 2010 and 2014 and a comparison with the 1990-2009 cohort.

Adv Clin Exp Med 2019 Apr 15. Epub 2019 Apr 15.

Department of Cardiac Surgery, Pomeranian Medical University in Szczecin, Poland.

Background: Sternal dehiscence is a serious postoperative complication of cardiac surgery observed in 0.2-5% of procedures performed by median sternotomy.

Objectives: Assessment of factors, including the method of sternum closure, which may affect the incidence of this complication. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/94154DOI Listing
April 2019
1 Read

Silicon intake and plasma level and their relationships with systemic redox and inflammatory markers in rheumatoid arthritis patients.

Adv Clin Exp Med 2019 Apr 15. Epub 2019 Apr 15.

Department of Food Science and Dietetics, Wroclaw Medical University, Poland.

Background: The nutritional significance of silicon for the human body is highlighted by a continually growing body of evidence. In conditions of excessive reactive oxygen species and upregulated immune response, silicon has been observed to provide benefits, but its role in redox and inflammatory status has not yet been examined in rheumatoid arthritis (RA).

Objectives: The aim of this study was to assess the relationship of silicon intake and plasma level to systemic indices of redox status and inflammation in patients with RA. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/105380DOI Listing
April 2019
1 Read

The radiological evaluation of the nasal cavity, conchae and nasal septum volumes by stereological method: A retrospective cone-beam computed tomography study.

Adv Clin Exp Med 2019 Apr 13. Epub 2019 Apr 13.

Department of Dentomaxillofacial Radiology, Faculty of Dentistry, Gaziantep University, Turkey.

Background: The nasal cavity (NC) is the entrance to the respiratory system. Many studies have been conducted on the structure, function and volume of the NC. Only a few studies were performed assessing the volumetric values of NC and conchae. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/98960DOI Listing

Relationship between quantitative parameters of lumbar vertebral perfusion and bone mineral density (BMD) in postmenopausal women.

Adv Clin Exp Med 2019 Apr 13. Epub 2019 Apr 13.

Department of Orthopedics, First Hospital of Longyan of Fujian Medical University, China.

Background: Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is a noninvasive method to evaluate the microcirculation of bone marrow in local tissue, which will be a new tool for the diagnosis of osteoporosis.

Objectives: To investigate the relationship between quantitative perfusion parameters (Ktrans, Kep and Ve) and bone mineral density (BMD) in postmenopausal women.

Material And Methods: The subjects were divided into 3 groups according to T value: normal bone mass group (T value ≥-1. Read More

View Article

Download full-text PDF

Source
http://www.advances.umed.wroc.pl/ahead-of-print/94150.pdf
Publisher Site
http://dx.doi.org/10.17219/acem/94150DOI Listing
April 2019
2 Reads

Preoperative and postoperative risk factors in laparoscopic cholecystectomy converted to open surgery.

Adv Clin Exp Med 2019 Apr 13. Epub 2019 Apr 13.

General Surgery Department, Atatürk Research and Education Hospital, Ankara, Turkey.

Background: Laparoscopic cholecystectomy (LC) is nowadays the gold standard in the surgical treatment of cholelithiasis and gallbladder diseases. But sometimes it may be inevitable to convert it to open surgery to safely end the procedure.

Objectives: In this study, we aimed to investigate the risk factors for conversion to open surgery from LC. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/81519DOI Listing
April 2019
1 Read

The Polish Prevalence of Infection in Intensive Care (PPIC): A one-day point prevalence multicenter study.

Adv Clin Exp Med 2019 Apr 13. Epub 2019 Apr 13.

Department of Anesthesiology and Intensive Care, Wrocław University Hospital, Poland.

Background: Infections in critically ill patients are the main reasons for a lack of therapeutic success and increased mortality in intensive care units (ICUs). There have been many analyses of the incidence of infections in ICUs; however, no large studies of this kind have been conducted either in Poland or in Eastern and Central Europe.

Objectives: The aim of the research was to undertake a one-day study of the prevalence of infections in ICUs in Warsaw and the Mazovian region of Poland. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/94147DOI Listing
April 2019
1 Read

The effectiveness of whole-body cryotherapy and physical exercises on the psychological well-being of patients with multiple sclerosis: A comparative analysis.

Adv Clin Exp Med 2019 Apr 5. Epub 2019 Apr 5.

Department of Psychiatry, Wroclaw Medical University, Poland.

Background: Due to the chronic character of multiple sclerosis (MS), non-pharmacological treatment can be applied. These therapies can be a good complementation to standard pharmacological treatment.

Objectives: The aim of the study was to evaluate the effectiveness of whole-body cryotherapy (WBC) and physical exercise training on the psychological and general well-being of patients with MS. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/104529DOI Listing
April 2019
3 Reads

Management of crossing vessels in children and adults: A multi-center experience with the transperitoneal laparoscopic approach.

Adv Clin Exp Med 2019 04 5. Epub 2019 Apr 5.

Department of Pediatric Urology, Jagiellonian University Medical College, Kraków, Poland.

Background: Crossing vessels (CVs) are common in older children and adults with hydronephrosis but no gold standard exists on how to treat this condition. The final decision is made intraoperatively by the surgeon.

Objectives: To assess the outcome of the laparoscopic dismembered pyeloplasty with translocation of the CVs in children and adults. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/94142DOI Listing

Relationship between the dietary glycemic load of the adult Polish population and socio-demographic and lifestyle factors - results of the WOBASZ II study.

Adv Clin Exp Med 2019 Apr 5. Epub 2019 Apr 5.

Department of Epidemiology, Cardiovascular Disease Prevention and Health Promotion, National Institute of Cardiology, Warszawa, Poland.

Background: Cardiovascular disease (CVD) occurs more often among people with a low sociodemographic status, so it is worth knowing if any sociodemographic factor also has an impact on diet quality, defined by glycemic load (GL).

Objectives: Assessment of the relationship between the sociodemographic and lifestyle factors, health status self-assessment and dietary GL of the adult Polish population based on WOBASZ II study results.

Material And Methods: The study included a representative group of the Polish population aged ≥20 years (2,554 men and 3,136 women). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/94151DOI Listing
April 2019
1 Read

Life activity, disease acceptance and quality of life in patients treated with renal replacement therapy since childhood.

Adv Clin Exp Med 2019 Apr 5. Epub 2019 Apr 5.

Department of Pediatrics and Nephrology, Medical University of Warsaw, Poland.

Background: Advances in the treatment of chronic kidney disease (CKD) resulted in expanding therapy goals from simple prolongation of life to a return to normal social functioning and having an active and satisfactory life after reaching adulthood.

Objectives: The aim of the study was to evaluate life activity, disease acceptance (DA) and quality of life (QOL) in patients with end-stage renal disease (ESRD) treated with renal replacement therapy (RRT) since childhood.

Material And Methods: We surveyed 117 patients aged . Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/94070DOI Listing
April 2019
2 Reads

The role of toll-like receptors in multifactorial mechanisms of early and late renal allotransplant injury, with a focus on the TLR4 receptor and mononuclear cells.

Adv Clin Exp Med 2019 Apr 5. Epub 2019 Apr 5.

Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, Poland.

The innate immune system is activated before an adaptive immune response. An expression of a particular toll-like receptor (TLR) in a transplanted kidney depends on the localization of specific cells (e.g. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/94139DOI Listing
April 2019
1 Read

Polyphenols and dietary antioxidant potential, and their relationship with arterial hypertension: A cross-sectional study of the adult population in Poland (WOBASZ II).

Adv Clin Exp Med 2019 Apr 8. Epub 2019 Apr 8.

Department of Hypertension, Angiology and Internal Medicine, Poznan University of Medical Sciences, Poland.

Background: Oxidative stress plays a key role in the development of most non-communicable diseases, including arterial hypertension (AH). Diet is the major source of exogenous antioxidants, which support the body in the elimination of excessive free radicals.

Objectives: To assess dietary total antioxidant potential (DTAP) and dietary polyphenol intake (DPI), and to determine the relationship between DTAP, DPI and hypertension in the Polish adult population; to indicate dietary sources of DTAP and DPI in participants with and without AH. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/91487DOI Listing

Comorbidities in chronic obstructive pulmonary disease: Results of a national multicenter research project.

Adv Clin Exp Med 2019 Mar;28(3):319-324

Department of Internal Medicine, Pulmonary Diseases and Allergy, Medical University of Warsaw, Poland.

Background: Chronic obstructive pulmonary disease (COPD) is associated with various comorbidities, which influence the course of COPD and worsen prognosis.

Objectives: The aim of this study was to analyze the comorbidities in a cohort of COPD patients in Poland during 12 months of observation.

Material And Methods: A total of 444 COPD patients (median age: 66. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/78024DOI Listing
March 2019
2 Reads

NFE2L2 is associated with NQO1 expression and low stage of hepatic fibrosis in patients with chronic hepatitis C.

Adv Clin Exp Med 2019 Mar 28. Epub 2019 Mar 28.

Central Laboratory, Medical University of Lodz, Poland.

Background: Oxidative stress is extremely important in the pathogenesis of chronic hepatitis C virus (HCV). In response to oxidative stress, adaptive antioxidant defenses are upregulated in the liver. The balance between antioxidant response and oxidative stress plays a key role in hepatic injury in HCV infection. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/105852DOI Listing

Detection rate of crossing vessels in pediatric hydronephrosis: Transperitoneal laparoscopy versus open lumbotomy.

Adv Clin Exp Med 2019 Mar 27. Epub 2019 Mar 27.

Department of Pediatric Surgery and Urology, Wroclaw Medical University, Poland.

Background: A bundle of crossing vessels (CV) supplying the lower pole of the kidney and causing mechanical obstruction of the ureteropelvic junction (UPJ) has been the subject of many discussions. During pyeloplasty, it is possible to overlook the CV. This may result in recurrent dilatation of the kidney and the need for re-surgery. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/104528DOI Listing
March 2019
3 Reads

Beyond the lungs: Alpha-1 antitrypsin's potential role in human gestation.

Adv Clin Exp Med 2019 Mar 27. Epub 2019 Mar 27.

Department of Genetics and Clinical Immunology, National Institute of Tuberculosis and Lung Diseases, Warszawa, Poland.

Alpha-1 antitrypsin (AAT) is an acute-phase protein with strong inhibitory activity towards proteolytic enzymes, mainly elastase but also trypsin, chymotrypsin and thrombin. The biological role of the protein and the effects of its deficiency have been subjects of scientific research for years, yet in many areas our knowledge remains incomplete. Alpha-1 antitrypsin deficiency (AATD), a defect in AAT synthesis and functionality, is one of the most frequently inherited genetic disorders among Caucasian populations. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/103668DOI Listing
March 2019
2 Reads

Vitamin D receptor (VDR) TaqI polymorphism, vitamin D and bone mineral density in patients with inflammatory bowel diseases.

Adv Clin Exp Med 2019 Mar 28. Epub 2019 Mar 28.

Institute of Human Genetics, Polish Academy of Sciences, Poznań, Poland.

Background: A common feature in the etiology of inflammatory bowel disease (IBD) and osteoporosis is a complex genetic background. Moreover, it has been shown that some of the susceptibility loci overlap for both diseases. One of the genes that may be involved in the pathogenesis of IBD as well as decreased bone mass is the vitamin D receptor (VDR) gene. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/97376DOI Listing
March 2019
3 Reads

Differential diagnosis of leukoplakia versus lichen planus of the oral mucosa based on digital texture analysis in intraoral photography.

Adv Clin Exp Med 2019 Mar 20. Epub 2019 Mar 20.

Department of Maxillofacial Surgery, Faculty of Military Medicine, Medical University of Lodz, Poland.

Background: A noninvasive, accurate and quick diagnosis is very important to general practitioners and specialists who care for the health of patients' oral cavity mucosa. The main enemies are precancerous lesions: leukoplakia and lichen planus (LP).

Objectives: The aim of this study was to attempt to formulate a differential diagnosis for leukoplakia vs LP in the oral mucosa based on digital texture analysis in intraoral macrophotography. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/104524DOI Listing

Evaluation of changes in enamel thickness after orthodontic treatment depending on the force applied to remove orthodontic brackets: OCT analysis and universal testing machine.

Adv Clin Exp Med 2019 Mar 19. Epub 2019 Mar 19.

Division of Orthodontics, Pomeranian Medical University, Szczecin, Poland.

Background: Adhesive materials used in orthodontics have contributed to the broadening of treatment options with fixed braces. The adhesive materials physically and chemically bond to the enamel surface and orthodontic bracket base, which, apart from offering advantages, also entails the risk of enamel damage when removing these materials from the tissue surface after the treatment is complete.

Objectives: The objective of this study was to assess how the bond strength of adhesive materials affects enamel thickness after removing brackets and whether the type of bonding system affects the amount of adhesive strength of the discussed materials. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/94141DOI Listing
March 2019
2 Reads

Association of total, acylated and unacylated ghrelin with apolipoprotein A1 and insulin concentrations in acromegalic patients.

Adv Clin Exp Med 2019 Mar 19. Epub 2019 Mar 19.

Department of Cell Biology, Poznan University of Medical Sciences, Poland.

Background: Ghrelin is a hormone that occurs in acylated (AG) or unacylated (UG) form. Ghrelin strongly stimulates growth hormone (GH) secretion from anterior pituitary, as well as regulates the energy balance and various metabolic parameters. Increased consideration is given to UG, thought to be inactive. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/97403DOI Listing
March 2019
2 Reads

Design and characteristics of new experimental chlorhexidine dental gels with anti-staining properties.

Adv Clin Exp Med 2019 Mar 18. Epub 2019 Mar 18.

Department of Dental Prosthetics, Wroclaw Medical University, Poland.

Background: Chlorhexidine-based products are often used in medicine and dentistry as dental hygiene and therapeutic products, especially by patients with various oral tissue diseases. However, these products have disadvantages, such as low stability, as well as discoloration of the teeth and dental reconstruction materials.

Objectives: The aim of this study was to create and evaluate experimental chlorhexidine (CHX) gels with anti-staining properties and to compare them with 3 commercially available products. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/94152DOI Listing

Urinary bladder hypertrophy and overactive bladder determine urinary continence after radical prostatectomy.

Adv Clin Exp Med 2019 Mar 14. Epub 2019 Mar 14.

Department of General and Oncologic Urology, Nicolaus Copernicus University, Bydgoszcz, Poland.

Background: Several clinical and biological factors exacerbate urinary incontinence (UI) and reduce the patient's quality of life after radical prostatectomy (RP).

Objectives: The purpose of this study was to evaluate the effects of urinary bladder hypertrophy and overactive bladder (OAB) on UI in patients after RP.

Material And Methods: Seventy patients were enrolled in the study and were divided into 2 groups: patients with bladder outlet obstruction (BOO) but without OAB (Group I; n = 20) and patients with BOO and OAB (Group II; n = 50). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/104532DOI Listing
March 2019
1 Read

Response to the article "Perioperative standards for the treatment of coagulation disorders and usage of blood products in patients undergoing liver transplantation used in the Clinic for Transplant Surgery in Wrocław".

Adv Clin Exp Med 2019 Mar;28(3):415-416

Department of Anesthesiology and Intensive Care, Medical University of Warsaw, Poland.

We read with interest the article by Łukaszewski et al. published in Advances in Clinical and Experimental Medicine:1211-1215, published online on July 18th, 2018, as ahead of print). As enthusiasts of promoting global assays of hemostasis, we would like to commend the authors for their commitment and effort in their implementation and clinical application. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/104539DOI Listing
March 2019
1 Read

The association of serum soluble Klotho levels and residual diuresis and overhydration in peritoneal dialysis patients.

Adv Clin Exp Med 2019 Mar 11. Epub 2019 Mar 11.

Department of Nephrology, Transplantology and Internal Medicine, Poznan University of Medical Sciences, Poland.

Background: Klotho, originally identified as an anti-aging factor, is a transmembrane protein expressed in the kidney. It has been reported that Klotho deficiency could be associated with a loss of residual renal function and cardiovascular complications in peritoneal dialysis (PD) patients.

Objectives: The main aim of the study was to evaluate whether serum levels of Klotho correlate with residual diuresis and hydration status in PD patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/104552DOI Listing
March 2019
3 Reads

Correlation of rs749292 and rs700518 polymorphisms in the aromatase gene (CYP19A1) with osteoporosis in postmenopausal Polish women.

Adv Clin Exp Med 2019 Mar 11. Epub 2019 Mar 11.

Department of Stem Cells and Regenerative Medicine, Institute of Natural Fibers and Medicinal Plants, Plewiska, Poland.

Material And Methods: The study included 675 unrelated women (109 women with osteopenia, 333 women with osteoporosis, and 233 healthy women). Genomic DNA was extracted from the blood samples and the CYP19A1 polymorphisms were determined using the polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) method. Bone mineral density at the lumbar spine (L1-L4) was measured with dual energy X-ray absorptiometry (DEXA). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/103803DOI Listing

The relationships between glycemic index and glycemic load of diets and nutritional status and antioxidant/oxidant status in the serum of patients with lung cancer.

Adv Clin Exp Med 2019 Mar 9. Epub 2019 Mar 9.

Department of Food Science and Nutrition, Wroclaw Medical University, Poland.

Background: A low glycemic index (GI) and glycemic load (GL) of diets as well as proper nutritional status may partially slow down depletion in antioxidant capacity, and may therefore have an impact on antioxidant/ oxidant status in lung cancer patients. However, no studies concerning these associations had previously been conducted.

Objectives: The aim of this study was to investigate the association between GI or GL and nutritional status and antioxidant/oxidant status in lung cancer patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/98952DOI Listing
March 2019
3 Reads

Circulating and circular RNAs and the need for rationalization and synthesis of the research spiral.

Adv Clin Exp Med 2019 Mar 6. Epub 2019 Mar 6.

Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Czech Republic.

In this essay, we aim to draw a short comparison between 2 important research topics - circular and circulating RNAs - and show how they are connected. The findings described here in the field of circular RNAs, which are still quite obscured by the rapidly expanding body of knowledge in biology, have added another dimension to our view of the process of gene expression, which is formed by a more complex network of molecule interactions than we previously thought. The term "circulating RNAs" refers to a broad spectrum of RNA fragments originating from different sources, such as physiologically dying cells, sites of inflammation or cancer cells, and fragments floating in human liquid tissues together with other elements. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/94148DOI Listing
March 2019
1 Read

Expression profile of Galp, alarin and their receptors in rat adrenal gland.

Adv Clin Exp Med 2019 Mar 6. Epub 2019 Mar 6.

Department of Histology and Embryology, Poznan University of Medical Sciences, Poland.

Background: Galanin-like peptide (Galp) and alarin (Ala) are 2 new members of the galanin peptide family. Galanin (Gal), the "parental" peptide of the entire family, is known to regulate numerous physiological processes, including energy and osmotic homeostasis, reproduction, food intake, and secretion of adrenocortical hormones. Galp and Ala are known to regulate food intake. Read More

View Article

Download full-text PDF

Source
http://www.advances.umed.wroc.pl/ahead-of-print/95039.pdf
Publisher Site
http://dx.doi.org/10.17219/acem/95039DOI Listing
March 2019
6 Reads

Serum testosterone depression as a factor influencing the general condition in chronic obstructive pulmonary disease patients.

Adv Clin Exp Med 2019 Mar 6. Epub 2019 Mar 6.

Department of Internal Medicine, Pulmonary Diseases and Allergy, Medical University of Warsaw, Poland.

Background: Testosterone has been recognized for its anabolic properties. It has been documented that in patients with chronic obstructive pulmonary disease (COPD), chronic hypoxia, disease severity, smoking, and corticosteroid treatment may contribute to low testosterone levels.

Objectives: The aim of the study was to evaluate the incidence of decreased serum testosterone concentration in male COPD patients and its influence on their condition. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/94153DOI Listing
March 2019
1 Read

Long-term administration of fenspiride has no negative impact on bone mineral density and bone turnover in young growing rats.

Adv Clin Exp Med 2019 Mar 6. Epub 2019 Mar 6.

Department of Pharmacology, Wroclaw Medical University, Poland.

Background: Fenspiride is an antagonist of H1-histamine receptors that is used to treat acute and chronic respiratory tract infections and otitis media in children and adolescents.

Objectives: The aim of the study was to assess the influence of long-term administration of fenspiride on bone mineral density (BMD) and bone turnover in young growing rats.

Material And Methods: The experiment was carried out on 18 young (8-week-old) male Wistar rats receiving either fenspiride 15 mg/kg intragastrically (ig) (group F) or saline solution 4 mL/kg ig (group C) for 3 months. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/93729DOI Listing
March 2019
3 Reads

Knockdown of long noncoding RNA Malat1 aggravates hypoxia-induced cardiomyocyte injury by targeting miR-217.

Adv Clin Exp Med 2019 Mar 7. Epub 2019 Mar 7.

Department of Cardiovascular Medicine, The 2nd Affiliated Hospital of Harbin Medical University, China.

Background: Expression of long noncoding (lncRNA) Malat1 can be increased by hypoxia in cardiomyocyte. Downregulation of Malat1 contributes to the reduction of cardiomyocyte apoptosis. However, the function of Malat1 in myocardial ischemia is unclear. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/93878DOI Listing

Does oral dryness influence quality of life? Current perspectives in elderly dental care.

Adv Clin Exp Med 2019 Mar 7. Epub 2019 Mar 7.

Department of Conservative Dentistry and Pedodontics, Wroclaw Medical University, Poland.

Background: The oral condition can functionally, socially and psychologically influence the quality of life. Oral dryness often occurs in the elderly due to the presence of systemic diseases and medications, which favors the development of many lesions and complaints, including dental caries, candidiasis, retention of full removable denture, taste disturbance and it enforces a change in nutrition.

Objectives: The aim of this study was to assess the impact of oral dryness on oral health-related quality of life in older subjects. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/104601DOI Listing
March 2019
7 Reads

Melatonin protects against streptozotocin-induced diabetic cardiomyopathy through the mammalian target of rapamycin (mTOR) signaling pathway.

Adv Clin Exp Med 2019 Mar 7. Epub 2019 Mar 7.

Department of Cardiology, Faculty of Medicine, Akdeniz University, Antalya, Turkey.

Background: Several studies demonstrated that the overexpression of mammalian target of rapamycin (mTOR) signaling protein is associated with cardiomyopathy. However, the effect of mTOR on the heart in hyperglycemic condition is still controversial.

Objectives: We aimed to investigate the expression of mTOR and antioxidant enzyme activity in cardiac hypertrophy in rats with streptozotocin-induced diabetes mellitus (DM), and the effects of the melatonin on diabetic cardiomyopathy (DCM). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/103799DOI Listing

Advanced heart failure: A review.

Adv Clin Exp Med 2019 Mar 4. Epub 2019 Mar 4.

1st Department of Cardiology, Faculty of Medicine, Poznan University of Medical Sciences, Poland.

Heart failure (HF) has been recognized as a pandemic and is a serious clinical and health problem associated with significant mortality, morbidity and expenditure on healthcare, especially among older people. Progress in medicine has made it possible for an increasing number of people with HF to live longer than ever before. Therefore, a new and serious clinical problem has appeared - advanced heart failure (AHF). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/103669DOI Listing

Negative body image in breast cancer patients.

Adv Clin Exp Med 2019 Feb 26. Epub 2019 Feb 26.

Division of Psychotherapy and Psychosomatic Medicine, Department of Psychiatry, Wroclaw Medical University, Poland.

The aim of this overview study is to familiarize readers with the impact of changes to body image (BI) among patients treated for breast cancer. Body image is subjected to many changes during oncological treatment and every method of treatment (surgery, chemotherapy, radiotherapy, and hormone therapy) can have a negative impact on the way the treated patients perceive their bodies. The article differentiates the susceptibility of patients to a worsened self-image due to their pre-disease personality, socioeconomic factors, age, and declared sense of control during the oncological treatment. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/103626DOI Listing
February 2019
1 Read

Biological and psychological components of depression in patients receiving IFN-alpha therapy for hepatitis C.

Adv Clin Exp Med 2019 Feb 27. Epub 2019 Feb 27.

Department of Psychiatry, Wroclaw Medical University, Poland.

Background: Depressive symptoms are frequent side effects of interferon α therapy (IFN-α). Both biological and psychological processes may occur concomitantly during hepatitis C treatment.

Objectives: This study was carried out to determine the impact of biological (immune response) and psychological factors on formation of depressive symptoms and major depressive disorder (MDD) during hepatitis C treatment. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/104617DOI Listing
February 2019
1 Read

Association of coronary artery disease with toll-like receptor 4 genetic variants: A meta-analysis.

Adv Clin Exp Med 2019 Feb 18. Epub 2019 Feb 18.

Department of Cardiology, Anhui Provincial Hospital of Anhui Medical University, Hefei, China.

Background: Toll-like receptor 4 (TLR4) plays an important role in the formation of coronary atherosclerotic plaque and the pathogenesis of coronary artery disease (CAD).

Objectives: The aim of the study was to conduct a meta-analysis assessing the relationship between 2 common genetic variants in the TLR4 gene (rs4986790 and rs4986791) and susceptibility to CAD.

Material And Methods: A systematic search of Web of Science, Embase, Scopus, Pubmed, and Wanfang Med Online was undertaken. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/91791DOI Listing
February 2019

The association between neurological diseases, malignancies and cardiovascular comorbidities among patients with bullous pemphigoid: Case-control study in a specialized Polish center.

Adv Clin Exp Med 2019 Feb 18. Epub 2019 Feb 18.

Department of Dermatology and Immunodermatology, Medical University of Warsaw, Poland.

Background: Bullous pemphigoid (BP) is the most common autoimmune bullous disease associated with higher mortality and coexisting comorbidities. The strongest relationship has been reported with neurological diseases (NDs) but the particular type of ND differed depending on the study. There are some doubts on the prevalence of other comorbidities. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/90922DOI Listing
February 2019
1 Read

Audiologic prognostic factors for hearing preservation following vestibular schwannoma surgery.

Adv Clin Exp Med 2019 Feb 19. Epub 2019 Feb 19.

Department of Otolaryngology, Medical University of Warsaw, Poland.

Background: Postoperative hearing loss after vestibular schwannoma (VS) removal still remains a lifelong problem for the patients. The present study analyzes the problem of hearing preservation after VS removal from a different angle than available professional literature on this topic.

Objectives: To identify audiologic factors which determine the extent of hearing loss in patients operated on for VS. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/90768DOI Listing
February 2019
4 Reads

Markers of acute kidney injury in children undergoing hematopoietic stem cell transplantation.

Adv Clin Exp Med 2019 Feb 11. Epub 2019 Feb 11.

Department of Pediatric Nephrology, Wroclaw Medical University, Poland.

Acute kidney injury (AKI), one of the major complications in children undergoing hematopoietic stem cell transplantation (HSCT), is an independent predictor of the patient's survival and a prognostic factor of progression to chronic kidney disease (CKD). Despite the multifaceted role of AKI, its early diagnosis in the course of HSCT remains a challenge. These difficulties may result from the inefficiency of traditional methods used to assess kidney function, like serum creatinine or estimated glomerular filtration rate. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/101573DOI Listing
February 2019
7 Reads

Matrix metalloproteinase-3 levels in relation to disease activity and radiological progression in rheumatoid arthritis.

Adv Clin Exp Med 2019 Feb 8. Epub 2019 Feb 8.

Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Fırat University, Elazığ, Turkey.

Background: Rheumatoid arthritis (RA) is a chronic inflammatory and systemic disease of unknown etiology that primarily affects synovial joints and involves progressive destruction around the joints. Inflammation starting in the joint synovium causes the destruction of cartilage, bone and other adjacent tissues with pannus formation.

Objectives: The aim of this study was to evaluate serum matrix metalloproteinase-3 (MMP-3) levels and their clinical and radiological significance in patients with rheumatoid arthritis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/94065DOI Listing
February 2019
2 Reads

MicroRNA-124 represses wound healing by targeting SERP1 and inhibiting the Wnt/β-catenin pathway.

Adv Clin Exp Med 2019 Feb 8. Epub 2019 Feb 8.

Jiangsu Liyang Zhimeixing Medical Cosmetic Clinic, China.

Background: Wound healing is a complex process which restores cellular structures and tissue layers after their destruction. Accumulating evidence has proven that microRNAs (miRs) are involved in wound healing.

Objectives: The aim of the study was to research the role of miR-124 in wound healing. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/94163DOI Listing
February 2019
1 Read

The clinical significance of intrahepatic Th22 cells in liver cirrhosis.

Adv Clin Exp Med 2019 Feb 8. Epub 2019 Feb 8.

Department of Gastroenterology, First Affiliated Hospital of Guangxi Medical University, Nanning, China.

Background: Th22 cells are a recently identified CD4+ T helper subset and have been implicated in the pathogenesis of certain diseases in humans, but the role of Th22 cells in liver cirrhosis (LC) remains unclear.

Objectives: The aim of the study was to investigate the expression and clinical significance of intrahepatic Th22 cells in LC tissues.

Material And Methods: Samples of liver tissue of 20 LC patients and 12 normal controls (NC) were collected. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/94062DOI Listing
February 2019
0.333 Impact Factor

A comparison of the remineralizing potential of dental restorative materials by analyzing their fluoride release profiles.

Adv Clin Exp Med 2019 Feb 8. Epub 2019 Feb 8.

Restorative Dentistry Department, Warsaw Medical University, Poland.

Background: The accessibility of the remineralizing ions in teeth's environment is essential for their incorporation into caries-affected dentin. Novel bioglass-reinforced materials capable of releasing fluoride, calcium and phosphates may be particularly useful in the tissue remineralization process. A novel restorative material, ACTIVA BioActive-Restorative (Pulpdent Corp. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/94140DOI Listing
February 2019
5 Reads

VEGF serum concentration and irreversible bronchoconstriction in adult asthmatics.

Adv Clin Exp Med 2019 Feb 8. Epub 2019 Feb 8.

Department of Internal Medicine and Allergology, Wroclaw Medical University, Poland.

Background: Vascular endothelial growth factor (VEGF) is an angiogenic, heparin-binding glycoprotein playing an important role in the pathogenesis of many diseases and disorders, including asthma. It has been reported that increased VEGF serum concentration is a biomarker of neovascularization, which could suggest that higher VEGF expression may be relevant to asthmatics with airway remodeling and irreversible bronchoconstriction.

Objectives: The aim of this study was to assess the possible association between VEGF serum concentration and irreversible bronchoconstriction in adult patients with a diagnosis of asthma. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/92012DOI Listing
February 2019

Arabic language skin-related stigmatization instruments: Translation and validation process.

Adv Clin Exp Med 2019 Feb 8. Epub 2019 Feb 8.

Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, Poland.

Background: Skin diseases are frequently the reason for social rejection. Therefore, the assessment of stigmatization level in patients suffering from dermatoses plays a crucial role in providing proper health service.

Objectives: The aim of this study was to create and validate Arabic language versions of stigmatization instruments - the 6-item Stigmatization Scale and the Feelings of Stigmatization Questionnaire. Read More

View Article

Download full-text PDF

Source
http://www.advances.umed.wroc.pl/ahead-of-print/102617.pdf
Publisher Site
http://dx.doi.org/10.17219/acem/102617DOI Listing
February 2019
11 Reads

The role of MR volumetry in brain atrophy assessment in multiple sclerosis: A review of the literature.

Adv Clin Exp Med 2019 Feb 6. Epub 2019 Feb 6.

Department of General Radiology, Interventional Radiology and Neuroradiology, Wroclaw Medical University, Poland.

We review the current role of magnetic resonance (MR) volumetry as a meaningful indicator of neurodegeneration and clinical disease progression in multiple sclerosis (MS) patients. Based on a review of the current literature we summarize the mechanisms that contribute to brain atrophy. We present the newest magnetic resonance imaging (MRI)-based methods used in atrophy quantification. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/94137DOI Listing
February 2019
1 Read

The effects of simvastatin on cellular viability, stemness and osteogenic differentiation using 3-dimensional cultures of stem cells and osteoblast-like cells.

Adv Clin Exp Med 2019 Feb 5. Epub 2019 Feb 5.

Department of Periodontics, College of Medicine, The Catholic University of Korea, Seoul, South Korea.

Background: Simvastatin has been reported to increase the therapeutic effects of many kinds of stem cells by increasing the number of those cells. However, the effects of simvastatin on the differentiation potential of stem cells have not been clearly determined.

Objectives: The aim of the study was to evaluate the effects simvastatin has on cellular viability, stemness and osteogenic differentiation using 3-dimensional cell spheroids of stem cells and osteoblast-like cells. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/94162DOI Listing
February 2019
1 Read

How to assess and predict success or failure of intra-detrusor injections with onabotulinumtoxinA.

Adv Clin Exp Med 2019 Feb 5. Epub 2019 Feb 5.

Department of Urology, Jagiellonian University Medical College, Kraków, Poland.

Intra-detrusor injection therapy with onabotulinumtoxinA is generally accepted as a highly effective, minimally invasive and well-tolerated day procedure for patients with refractory overactive bladder (OAB) and neurogenic detrusor overactivity (NDO). The aim of this study was to summarize currently available methods of assessing treatment efficacy and risk factors that may influence the therapeutic effect of this approach. We found that there are discrepancies in the assessment methods. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17219/acem/90764DOI Listing
February 2019