1,323 results match your criteria Advanced biomedical research[Journal]


A Survey on Inhibitory Effect of Whole-Body Extraction and Secretions of 's Larvae on .

Adv Biomed Res 2020 16;9:12. Epub 2020 Mar 16.

Department of Medical Parasitology and Mycology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: Leishmaniasis is a skin disease caused by parasite. Despite being self-limiting, must be treated. Available drugs have side effects and drug resistance has also been seen. Read More

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http://dx.doi.org/10.4103/abr.abr_56_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147512PMC

The Prevalence of Human Immunodeficiency Virus Infection in Patients with Sexually Transmitted Diseases.

Adv Biomed Res 2020 16;9:11. Epub 2020 Mar 16.

Brucellosis Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.

Background: Human immunodeficiency virus (HIV) transmission pattern in Iran has been changed from injection drug to sexual contact. Lack of accurate assessment of HIV in people with sexually transmitted diseases (STDs) in Iran prompted us to conduct this study to determine the frequency of HIV infection in these patients.

Materials And Methods: In this cross-sectional study which conducted in 2016-2017, overall, 190 patients with STDs referring to two hospitals of Hamadan were enrolled in the study. Read More

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http://dx.doi.org/10.4103/abr.abr_233_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147514PMC

Evaluation the Effects of Essential Oil and Hypertonic Saline as Scolicidal Agents in Induction of Sclerosing Cholangitis in Rabbits.

Adv Biomed Res 2020 28;9. Epub 2020 Feb 28.

Department of Radiology, Shiraz University of Medical Sciences, Shiraz, Iran.

Background: There are several scolicidal agents for inactivation of hydatid cyst protoscolices during surgery, but most of them are associated with adverse side effects such as sclerosing cholangitis (SC) and liver necrosis. The present study aimed to evaluate the adverse effects of essential oil to induce SC in animal models.

Materials And Methods: Eighteen rabbits weighting 2000-3500 g were included in three groups for this study. Read More

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http://dx.doi.org/10.4103/abr.abr_210_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147516PMC
February 2020

Vitamin D Status in Infants during the First 9 Months of Age and its Effect on Growth and Other Biochemical Markers: A Prospective Cohort Study.

Adv Biomed Res 2020 28;9. Epub 2020 Feb 28.

Department of Radiodiagnosis, King George's Medical College, Lucknow, Uttar Pradesh, India.

Background: Despite food fortification policies in many countries and recommendations for Vitamin D supplementation of at-risk groups, Vitamin D deficiency (VDD) and infantile rickets remain major public health challenges in many developed and developing countries.

Materials And Methods: Ninety-six participants at birth were enrolled and followed up until 9 months of age. Serum 25OHD was estimated in cord blood at birth and at 14 ± 1 weeks of life. Read More

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http://dx.doi.org/10.4103/abr.abr_242_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147515PMC
February 2020

Infodemic and Risk Communication in the Era of CoV-19.

Adv Biomed Res 2020 11;9:10. Epub 2020 Mar 11.

Applied Physiology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

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http://dx.doi.org/10.4103/abr.abr_47_20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147513PMC

The Effects of Fibrin-icariin Nanoparticle Loaded in Poly (lactic-co-glycolic) Acid Scaffold as a Localized Delivery System on Chondrogenesis of Human Adipose-derived Stem Cells.

Adv Biomed Res 2020 25;9. Epub 2020 Feb 25.

Department of Anatomical Sciences and Molecular Biology, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: Nowadays, cartilage tissue engineering is the best candidate for regeneration of cartilage defects. This study evaluates the effect of fibrin/icariin (ICA) nanoparticles (F/I NPs) on chondrogenesis of stem cells.

Materials And Methods: F/I NPs were characterized by Dynamic Light Scattering DLS. Read More

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http://dx.doi.org/10.4103/abr.abr_143_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059457PMC
February 2020

Anti- Activities of the Hydroalcoholic Extract of Some Species.

Adv Biomed Res 2020 21;9. Epub 2020 Jan 21.

Department of Pharmacognosy and Biotechnology, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran.

Background: () is a protozoan parasite that infects a wide range of warm-blooded animals and humans. The conventional anti- treatments cause significant toxicity. family contains several medicinal plants with anti-inflammatory, chemopreventive, insecticide, antibacterial, antiviral, and antiparasitic effects. Read More

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http://dx.doi.org/10.4103/abr.abr_206_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003551PMC
January 2020

Identification of Dermatophyte and Nondermatophyte Molds Isolated from Animal Lesions Suspected to Dermatomycoses.

Adv Biomed Res 2020 21;9. Epub 2020 Jan 21.

Department of Medical Parasitology and Mycology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: Dermatomycoses contain superficial fungal infections of keratinized layers of the body such as skin, hair, and nail that affect more than 20%-25% of people and animals worldwide. Some fungi can cause superficial infections in animals after accidental penetration and colonization on injured skin and can be transmitted to humans by exposure. The infection caused mainly by dermatophyte species and may also be caused rarely by yeasts and nondermatophytic molds. Read More

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http://dx.doi.org/10.4103/abr.abr_230_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003554PMC
January 2020

The Relationship between Aura and Postoperative Outcomes of Epilepsy Surgery in Patients with Mesial Temporal Sclerosis.

Adv Biomed Res 2020 21;9. Epub 2020 Jan 21.

Department of Neurology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: We conducted a study to evaluate the relationship between aura types and postoperative outcomes in patients with mesial temporal sclerosis (MTS) to predict the prognosis of patients, accordingly.

Materials And Methods: In this cross-sectional study, 99 patients with MTS-temporal lobe epilepsy were enrolled based on inclusion and exclusion criteria. The types of aura were evaluated, and the outcomes were categorized according to the Engel scale. Read More

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http://dx.doi.org/10.4103/abr.abr_25_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003553PMC
January 2020

What Components of Adolescents' Responsibility are Effective in Preventing Addiction?

Adv Biomed Res 2020 21;9. Epub 2020 Jan 21.

Department of Community and Family Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: In most countries, the age of addiction is declining, and the prevalence of adolescent addiction is increasing. Many factors can affect the addiction tendency; one of them can be a sense of responsibility. This study was designed to evaluate the probable relation between addiction tendency and responsibility. Read More

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http://dx.doi.org/10.4103/abr.abr_204_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003555PMC
January 2020

Knowledge, Attitude, and Pattern of Physical Activity in Middle School Students in Isfahan, 2015.

Adv Biomed Res 2020 21;9. Epub 2020 Jan 21.

Department of Community and Family Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: The incidence of overweight and obesity in children has increased in recent decades. Physical activity (PA), which is a multidimensional behavior, has an important role in preventing and decreasing obesity. The aim of the study is to evaluate the knowledge, attitude, and exercise habits of middle school students and also explore the differences regarding demographic variables in Isfahan, Iran. Read More

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http://dx.doi.org/10.4103/abr.abr_75_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003552PMC
January 2020

An Assessment between D1 Receptor Agonist and D2 receptor Antagonist into the Ventral Tegmental Area on Conditioned Place Preference and Locomotor Activity.

Adv Biomed Res 2019 24;8:72. Epub 2019 Dec 24.

Department of Physiology, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: The release of dopamine (DA) has certain roles in the induction of conditioned place preference (CPP) and motor learning in the ventral tegmental area (VTA). The aim of this study was to investigate the excitatory effects of DA through DA-D1 agonist (SKF38393) and elimination of the inhibitory effects of DA through DA-D2 antagonist (eticlopride) into the VTA and its synergistic effects with an ineffective dose of morphine in the induction of CPP.

Materials And Methods: Morphine (2. Read More

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http://dx.doi.org/10.4103/abr.abr_82_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952765PMC
December 2019

Cloning, Optimization of Periplasmic Expression and Purification of Recombinant Granulocyte Macrophage-Stimulating Factor in BL21 (DE3).

Adv Biomed Res 2019 24;8:71. Epub 2019 Dec 24.

Department of Pharmaceutical Biotechnology, Isfahan Pharmaceutical Research Center, Faculty of Pharmacy, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: Molgramostim, a nonglycosylated version of recombinant granulocyte-macrophage colony-stimulating factor (GM-CSF), can be produced in a high level by . However, overexpression of GM-CSF in bacterial cells usually leads to formation of inclusion bodies and insoluble protein aggregates which are not biologically active. The aim of the present study was to improve the expression of soluble and biologically active GM-CSF in periplasmic space of BL21 (DE3). Read More

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http://dx.doi.org/10.4103/abr.abr_166_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952766PMC
December 2019

Tuberculous Uveitis, Erythema Induratum, and Persistent Genital Warts in a Female Patient: A Rare Case Report.

Adv Biomed Res 2019 27;8:70. Epub 2019 Nov 27.

Psoriasis Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.

Uveitis and erythema induratum are two uncommon extrapulmonary manifestations of tuberculosis (TB). In most circumstances, we cannot isolate mycobacterium from those sites, so diagnosis is difficult. In the presented case, panuveitis, erythema induratum, and persistent anogenital warts were found concurrently in a 19-year-old girl who had a history of pulmonary TB 10 years ago. Read More

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http://dx.doi.org/10.4103/abr.abr_154_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909546PMC
November 2019

Diagnostic Performance of Ultrasonography in Detecting Fatty Liver Disease in Comparison with Fibroscan in People Suspected of Fatty Liver.

Adv Biomed Res 2019 27;8:69. Epub 2019 Nov 27.

Department of Gastroenterologist, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: Fatty liver disease is a common hepatic disorder that remains undiagnosed due to the high number of asymptomatic patients and lack of a proper noninvasive diagnostic tool. Liver biopsy, the gold standard of liver steatosis diagnosis, is an invasive method that can be replaced by fibroscan. Fibroscan can detect liver steatosis with high sensitivity and specificity, but it is not accessible around the world. Read More

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http://dx.doi.org/10.4103/abr.abr_114_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909544PMC
November 2019

Comparing the Effect of Henna Oil and Olive Oil on Pressure Ulcer Grade One in Intensive Care Units Patients.

Adv Biomed Res 2019 27;8:68. Epub 2019 Nov 27.

Department of Critical Care Nursing, Faculty of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: One of the most common problems in the intensive care unit (ICU) is the incidence of pressure ulcer or bedsore. This research was conducted with the aim to compare the effect of henna and olive on pressure ulcer grade one in ICU patients hospitalized in the selected hospitals of Isfahan University of Medical Science in 2016.

Materials And Methods: This study conducted on 108 ICU patients with pressure ulcer. Read More

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http://dx.doi.org/10.4103/abr.abr_207_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909547PMC
November 2019

The Effect of Melatonin on Anxiety and Pain of Tourniquet in Intravenous Regional Anesthesia.

Adv Biomed Res 2019 27;8:67. Epub 2019 Nov 27.

Department of Anesthesiology, Imam Khomeini Hospital, Urmia University of Medical Sciences, Urmia, Iran.

Background: Melatonin has anxiolytic and potential analgesic effects. Several studies have indicated the sedative and anti-anxiety effects of melatonin when used as premedication before surgery. Hence, we assessed the efficacy of melatonin premedication in tourniquet-related pain and analgesia in patients receiving intravenous regional anesthesia (IVRA). Read More

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http://dx.doi.org/10.4103/abr.abr_106_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909545PMC
November 2019

Evaluation of Diabetes Effects on the Expression of Leukemia Inhibitory Factor and Vascular Endothelial Growth Factor A Genes and Proteins at the Time of Endometrial Receptivity after Superovulation in Rat Model.

Adv Biomed Res 2019 27;8:66. Epub 2019 Nov 27.

Department of Anatomical Sciences, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: Diabetes, a major metabolic disorder, seems to affect the fertility rates of women in various ways. Due to the uncertainty of the effects of diabetes along with superovulation treatment on the infertility, we investigate the effects of ovulation induction treatment as therapeutic approach on the expression of leukemia inhibitory factor (LIF) and vascular endothelial growth factor A (VEGFA) as two main factors which are involved in the implantation in the streptozotocin (STZ)-induced type 1 diabetic rats.

Materials And Methods: Type 1 diabetes was induced by injections of STZ in Wistar rats. Read More

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http://dx.doi.org/10.4103/abr.abr_159_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909543PMC
November 2019

Improvement of Soluble Production of Reteplase in by Optimization of Chemical Chaperones in Lysis Buffer.

Adv Biomed Res 2019 31;8:65. Epub 2019 Oct 31.

Department of Pharmaceutical Biotechnology, Isfahan Pharmaceutical Research Center, Faculty of Pharmacy, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: Reteplase is a nonglycosylated derivative of recombinant tissue plasminogen activator, a thrombolytic agent, which can be easily expressed in . However, overexpression of reteplase in usually leads to accumulation of insoluble and inactive aggregates and inclusion bodies. In the present study, we aimed to optimize chemical additives of lysis buffer to avoid the initial aggregation and formation of inclusion bodies of reteplase at cell disruption step. Read More

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http://dx.doi.org/10.4103/abr.abr_212_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839271PMC
October 2019

Interaction of Sex Hormones and the Renin-Angiotensin System in Ovariectomized Rats Subjected to Ischemia-Reperfusion Induction.

Adv Biomed Res 2019 31;8:64. Epub 2019 Oct 31.

Department of Physiology, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.

Backgrounds: Ischemia-reperfusion (IR) injuries occur in a variety of clinical conditions, which lead to kidney damage. Most of the tissue damages after IR are due to the activation of the renin-angiotensin system (RAS). Hence, in this study, the interaction of sex hormones and RAS in ovariectomized (OV) rats subjected to IR induction has been studied. Read More

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http://dx.doi.org/10.4103/abr.abr_172_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839270PMC
October 2019

Histone Deacetylases and Histone Deacetylase Inhibitors: Molecular Mechanisms of Action in Various Cancers.

Adv Biomed Res 2019 31;8:63. Epub 2019 Oct 31.

Research Center for Noncommunicable Diseases, Jahrom University of Medical Sciences, Jahrom, Iran.

Epigenetic modifications such as histone modification play an important role in tumorigenesis. There are several evidence that histone deacetylases (HDACs) play a key role in cancer induction and progression by histone deacetylation. Besides, histone acetylation is being accessed as a therapeutic target because of its role in regulating gene expression. Read More

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http://dx.doi.org/10.4103/abr.abr_142_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839273PMC
October 2019

Comparison of Nutritional Behaviors and Physical Activities between Overweight/Obese and Normal-Weight Adults.

Adv Biomed Res 2019 31;8:62. Epub 2019 Oct 31.

Department of Community and Family Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: Overweight and obesity are major problems with increasing rates among adult populations. Nutritional behaviors and physical activity are the most important influencing factors. In this article, we conducted a survey on the nutritional behaviors and physical activities among normal-weight and overweight/obese adults. Read More

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http://dx.doi.org/10.4103/abr.abr_134_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839272PMC
October 2019

Evaluation of Different Concentrations of Imatinib on the Viability of : An Study.

Adv Biomed Res 2019 31;8:61. Epub 2019 Oct 31.

Department of Dermatology, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: Leishmaniasis is an infectious disease caused by an intracellular parasite of and is transmitted through the female sandflies bite and may lead to severe skin lesions. Although drugs such as antimony compounds are available, their side effects such as toxicity, low efficacy, and emergence of resistance have raised the importance of effective replacement. Imatinib, as an inhibitor of tyrosine kinase (TK) of , stops abnormal function of TK such as Bcr-Abl through assembling into transmembrane pores in a sterol-dependent manner. Read More

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http://dx.doi.org/10.4103/abr.abr_58_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839269PMC
October 2019

Successful Myomectomy in the Second Trimester of Pregnancy.

Adv Biomed Res 2019 30;8:60. Epub 2019 Sep 30.

Department of Obstetrics and Gynecology, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

The prevalence of uterine myomas during pregnancy is estimated to be small. However, a significant fraction of these could lead to pregnancy complications. Myomectomy is rarely performed during pregnancy because of fear of miscarriage and the risk of uncontrolled hemorrhage necessitating hysterectomy. Read More

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http://dx.doi.org/10.4103/abr.abr_236_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796287PMC
September 2019
1 Read

Effectiveness of Dialectical Behavioral Therapy on Executive Function, Emotional Control and Severity of Symptoms in Patients with Bipolar I Disorder.

Adv Biomed Res 2019 30;8:59. Epub 2019 Sep 30.

Department of Epidemiology and Biostatistics, School of Public Health, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: Bipolar disorder is a disabling illness characterized by recurrent episodes of mania, hypomania, and depression. The dialectical behaviour therapy (DBT) is basically designed to help regulate excitement, tolerance of discomfort, mindfulness and interpersonal relationships. This study aimed to determine the effectiveness of DBT on executive function, emotional control and symptom relief in patients with type 1 bipolar disorder. Read More

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http://dx.doi.org/10.4103/abr.abr_42_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6796294PMC
September 2019
4 Reads

Molecular Characterization of Isolated from Ventilator-Associated Pneumonia and Burn Wound Colonization by Random Amplified Polymorphic DNA Polymerase Chain Reaction and the Relationship between Antibiotic Susceptibility and Biofilm Production.

Adv Biomed Res 2019 23;8:58. Epub 2019 Sep 23.

Department of Microbiology, Iran University of Medical Sciences, Tehran, Iran.

Background: Multidrug-resistant can cause complications in antibiotic therapy and increase the rate of morbidity and mortality in hospitalized patients. Patients with ventilator and burns are two specific groups at high risk for infections. This study aimed to determine antibiotic susceptibility patterns associated with biofilm production in and to assess its molecular epidemiology by random amplified polymorphic DNA polymerase chain reaction (RAPD PCR) in isolated from ventilator-associated pneumonia and burn wound colonization. Read More

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http://dx.doi.org/10.4103/abr.abr_256_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777144PMC
September 2019
1 Read

The Effects of Gonadotropin-Releasing Hormone Analog and a Combination of Gonadotropin-Releasing Hormone Analog and Recombinant Human Growth Hormone on Adult Height in Girls with Early Puberty.

Adv Biomed Res 2019 23;8:57. Epub 2019 Sep 23.

Clinical Research Unit, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Background: Early puberty (EP) is due to the activation of gonadotropin-releasing hormone (GnRH) pulse generator in lower ages; EP may be a potential cause for impairment of adult height, leading to short stature. The aim of this study was to determine the effects of GnRH analog (GnRHa) and GnRHa plus recombinant human growth hormone (rhGH) treatment on final height in healthy girls with EP.

Materials And Methods: Fifty EP girls (sexual maturity rating: 2-3) with chronological age (CA) 9. Read More

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http://dx.doi.org/10.4103/abr.abr_121_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777143PMC
September 2019
1 Read

Expression of CXC Chemokine Receptors in Acute Ulcerative Colitis: Initial Study from an Animal Model.

Adv Biomed Res 2019 23;8:56. Epub 2019 Sep 23.

Cancer and Immunology Research Center, Kurdistan University of Medical Sciences, Faculty of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran.

Background: Ulcerative colitis (UC) is an inflammatory disease which is characterized by infiltration of inflammatory cells, crypt abscesses, distortion of the mucosal glands, and goblet cell depletion. The existence of neutrophil-rich inflammation in colon tissues of patients with UC is one of the most significant histological features of this disease. Nonetheless, the expression of CXCR chemokine receptors which appear as the main chemical mediators governing the migration of neutrophils into the mucosal tissue of patients with UC has not been well clarified. Read More

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http://dx.doi.org/10.4103/abr.abr_55_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777142PMC
September 2019

Genetic Study of Hepatocyte Nuclear Factor 1 Alpha Variants in Development of Early-Onset Diabetes Type 2 and Maturity-Onset Diabetes of the Young 3 in Iran.

Adv Biomed Res 2019 23;8:55. Epub 2019 Sep 23.

Department of Genetics and Molecular Biology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: Maturity-onset diabetes of the young (MODY) is a clinically and genetically heterogeneous group of diabetes characterized by noninsulin-dependent, autosomal-dominant disorder with strong familial history, early age of onset, and pancreatic beta-cell dysfunction. Mutations in at least 14 different genes are responsible for various MODY subtypes. Heterozygous mutations in the hepatocyte nuclear factor 1 alpha () gene are responsible for the MODY3 subtype, which is a common subtype of MODY in different studied populations. Read More

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http://dx.doi.org/10.4103/abr.abr_54_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777141PMC
September 2019
2 Reads

Surprisingly, the Result of an Unplanned Pregnancy after Cranial Radiotherapy: A Case Report (Successful Childbirth after Brain Astrocytoma).

Adv Biomed Res 2019 23;8:54. Epub 2019 Sep 23.

Department of General Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

The present study aimed to present a rare case of successful pregnancy within 6 months from cranial mass surgery and postsurgical radiotherapy. A 32-year-old female with gestational age of 19 weeks had been refereed with a past medical history of recently treated brain astrocytoma. Close obstetric monitoring had been planned; the pregnancy was complicated with severe preeclampsia at the gestational age of 36 weeks, which leads to successful delivery. Read More

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http://dx.doi.org/10.4103/abr.abr_51_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777140PMC
September 2019

Evaluation of SEPP1 and Selenoprotein S Gene Polymorphisms (rs7579 and rs34713741) in Relation to Colorectal Cancer Susceptibility in Subset of Iranian Population: A Case-control Study.

Adv Biomed Res 2019 25;8:47. Epub 2019 Jul 25.

Depatment of Genetics and Molecular Biology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: Colorectal cancer (CRC) is rated as the second cause of cancer death worldwide. Selenium (Se) has antioxidant activity and antitumor effect, especially in colon cancer. This important role occurs through selenoproteins. Read More

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http://dx.doi.org/10.4103/abr.abr_249_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683409PMC

A Novel Algorithm in Radiation Dosimetry of Regular and Irregular Treatment Fields.

Adv Biomed Res 2019 25;8:46. Epub 2019 Jul 25.

Department of Medical Physics, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: The aim of this study was to design an algorithm for the calculation of monitor unit (MU) in a short time and high precision for different radiotherapy (RT) fields.

Materials And Methods: The algorithm for calculating MU for the stated patients was designed in MATLAB software. To investigate the efficiency of this algorithm, 11 regular chest fields with the sizes of 7 cm × 7 cm up to 17 cm × 17 cm were considered, and the obtained MUs were compared with MUs of 13 patients which were calculated with a "hand calculation" which is used in some RT centers for the aforementioned fields. Read More

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http://dx.doi.org/10.4103/abr.abr_238_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683408PMC

Development and Primary Evaluation of a Smartphone Application for Blood Glucose Control in Hospitalized Patients.

Adv Biomed Res 2019 25;8:45. Epub 2019 Jul 25.

Isfahan Endocrine and Metabolism Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: Diabetes is one of the major causes of morbidity and mortality. Diabetes and hyperglycemia are leading causes for cardiovascular diseases, chronic infections, and other serious problems. The use of smartphone is dramatically increasing, and as such, it is sensible to use an application for management of hospitalized patients with diabetes or hyperglycemia. Read More

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http://dx.doi.org/10.4103/abr.abr_188_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683406PMC

Evaluating the Effect of Oral Gabapentin on the Improvement of Gastrointestinal Symptoms in Patients with Functional Dyspepsia Resistant to Conventional Treatments.

Adv Biomed Res 2019 21;8:53. Epub 2019 Aug 21.

Department of Gastrointestinal and Liver Disease, Najafabad Islamic Azad University, Isfahan, Iran.

Background: Dyspepsia is one of the most common gastrointestinal (GI) problems and is more prevalent in adults. Environmental hypersensitivity and anxiety and depression are among the factors that can cause this disease. In this regard, gabapentin as a gamma-aminobutyric acid (GABA) analog used in the treatment of neuropathic pain and may be effective in controlling the symptoms of GI disorders. Read More

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http://dx.doi.org/10.4103/abr.abr_234_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712892PMC
August 2019
1 Read

Effect of 5-Aza-2'-Deoxycytidine in Comparison to Valproic Acid and Trichostatin A on Histone Deacetylase 1, DNA Methyltransferase 1, and CIP/KIP Family (p21, p27, and p57) Genes Expression, Cell Growth Inhibition, and Apoptosis Induction in Colon Cancer SW480 Cell Line.

Adv Biomed Res 2019 21;8:52. Epub 2019 Aug 21.

Research Center for Noncommunicable Diseases, Jahrom University of Medical Sciences, Jahrom, Fars Province, Iran.

Background: Cancer initiation and progression depends on genetic and epigenetic alterations such as DNA methylation and histone modifications. Hypermethylation and deacetylation of the CIP/KIP family (p21, p27, and p57) lead to tumorigenesis. Our previous study indicated that DNA methyltransferase (DNMT) inhibitor and histone deacetylase (HDAC) inhibitors can inhibit cell growth and induce apoptosis. Read More

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http://dx.doi.org/10.4103/abr.abr_91_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712896PMC
August 2019
1 Read

The Radioprotective Effect of Combination of Melatonin and Metformin on Rat Duodenum Damage Induced by Ionizing Radiation: A Histological Study.

Adv Biomed Res 2019 21;8:51. Epub 2019 Aug 21.

Department of Medical Physics and Biomedical Engineering, School of Medicine, Tehran University of Medical Science, International Campus, Tehran, Iran, Misan, Iraq.

Background: Radiation toxicity is one of the major concerns for patients with gastrointestinal cancers that undergo radiotherapy. Duodenum is one of the most radiosensitive parts of gastrointestinal system that may be exposed to a high dose of radiation during radiotherapy for some cancers. The development or identification of appropriate radioprotectors with less toxicity is an interesting aim in radiobiology for clinical radiotherapy applications. Read More

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http://www.advbiores.net/text.asp?2019/8/1/51/264926
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http://dx.doi.org/10.4103/abr.abr_68_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712895PMC
August 2019
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Evaluation of Syndesmosis Reduction after Removal Syndesmosis Screw in Ankle Fracture with Syndesmosis Injury.

Adv Biomed Res 2019 21;8:50. Epub 2019 Aug 21.

Department of Anesthesiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Background: Ankle fracture-dislocation with a syndesmotic injury has been treated with syndesmotic screw fixation. There are little evidences about the safety and efficacy of syndesmotic screw removal on the syndesmotic malreduction. This study aimed to evaluate the effects of syndesmotic screw removal of distal attachment of the fibula and tibia bones on the syndesmotic reduction and also impact of syndesmotic screw removal on the final functional score of ankle joint. Read More

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http://dx.doi.org/10.4103/abr.abr_66_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712893PMC
August 2019
4 Reads

An Overview of the CRISPR-Based Genomic- and Epigenome-Editing System: Function, Applications, and Challenges.

Adv Biomed Res 2019 21;8:49. Epub 2019 Aug 21.

Department of Medical Genetics, Mashhad University of Medical Sciences, Mashhad, Iran.

Developing a new strategy for an efficient targeted genome editing has always been a great perspective in biology. Although different approaches have been suggested in the last three decades, each one is confronting with limitations. CRISPR-Cas complex is a bacterial-derived system which made a breakthrough in the area of genome editing. Read More

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http://dx.doi.org/10.4103/abr.abr_41_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712897PMC

Vitamin D Receptor rs2228570 and rs731236 Polymorphisms are Susceptible Factors for Systemic Lupus Erythematosus.

Adv Biomed Res 2019 21;8:48. Epub 2019 Aug 21.

Department of Internal Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.

Background: The Vitamin D receptor () polymorphisms are the candidate genetic variants for susceptibility to different disease including autoimmune disorders. In the present study, we aimed to assess the association between polymorphisms and systemic lupus erythematosus (SLE) susceptibility in Southeast Iranian population.

Materials And Methods: One hundred and twenty-seven patients with SLE and 139 controls were genotyped for rs2228570, rs731236, and rs7975232 polymorphisms using polymerase chain reaction-restriction fragment length polymorphism method. Read More

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http://dx.doi.org/10.4103/abr.abr_19_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712894PMC
August 2019
1 Read

Comparison of Pulmonary Function Test in Petrol Pump Worker and Auto-rickshaw Driver.

Adv Biomed Res 2019 28;8:44. Epub 2019 Jun 28.

Junior Resident, Department of Physiology, AIIMS, Bhopal, Madhya Pradesh, India.

Background: Rapid rise in petrol pump filling station is seen in the last decade, and air pollution had increased drastically. Air pollutants and components in petrol may have delirious effect on respiratory health. Petrol pump workers are exposed to both factors, whereas auto-rickshaw drivers are exposed mainly to air pollutants. Read More

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http://dx.doi.org/10.4103/abr.abr_204_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6621343PMC
June 2019
4 Reads

Comparison of Haloperidol, Promethazine, Trifluoperazine, and Chlorpromazine in Terms of Velocity and Durability of the Sedation among Acute Aggressive Patients: A Randomized Clinical Trial.

Adv Biomed Res 2019 28;8:43. Epub 2019 Jun 28.

Department of Epidemiology and Biostatistics, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: Knowledge and skill about sedation of aggressive patients is necessary for each psychiatrist. The purpose of this study was comparing the velocity and durability of sedation induced by the haloperidol, trifluoperazine, promethazine, and chlorpromazine in aggressive patients.

Materials And Methods: This randomized clinical trial was done on 76 aggressive patients referred to Psychiatry Emergency Service of Noor Hospital of Isfahan University of Medical Sciences that were randomly divided into four groups of haloperidol, promethazine, chlorpromazine, and trifluoperazine. Read More

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http://dx.doi.org/10.4103/abr.abr_229_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6621353PMC
June 2019
3 Reads

The Effect of Three Different Insoles on Ankle Movement Variability during Walking in Athletes with Functional Ankle Instability.

Adv Biomed Res 2019 28;8:42. Epub 2019 Jun 28.

School of Health Sciences, University of Salford, Salford, UK.

Background: Increased ankle movement variability has been reported in people with functional ankle instability (FAI). The purpose of this study was to investigate the effect of textured insole, lateral wedge, and textured lateral wedge insole on ankle movement variability during walking in athletes with FAI.

Materials And Methods: Twenty-one athletes diagnosed with FAI participated in this before-after study. Read More

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http://dx.doi.org/10.4103/abr.abr_69_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6621341PMC
June 2019
1 Read

Renal Tissue Damages and Its Antioxidant Status Improved by Crab Shell Extract in Streptozotocin-induced Diabetic Rat.

Adv Biomed Res 2019 28;8:41. Epub 2019 Jun 28.

Fertility and Infertility Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Background: Diabetic nephropathy is a complex and multifactorial adverse effect of diabetes mellitus (DM). Crab shell as a natural product is supposed to have antioxidant effect which is one of the important mechanisms to improve DM. The aim of this study was to investigate the effect of crab shell extract (CSE) on the histopathology and antioxidant status of kidney in diabetic rats. Read More

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http://dx.doi.org/10.4103/abr.abr_65_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6621417PMC
June 2019
1 Read

Microsatellite Marker Analysis for Laboratory Mice Profiling.

Adv Biomed Res 2019 28;8:40. Epub 2019 Jun 28.

Department of Quality Control, Pasteur Institute of Iran, Tehran, Iran.

Background: The key point in the production procedure of inbred animals is checking the genetic purity. Skin grafting and coat color test are used traditionally to prove genetic purity, but they have some disadvantages. Recent advances in DNA profiling have enabled scientists to check easily the genetic purity of laboratory animals. Read More

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http://dx.doi.org/10.4103/abr.abr_53_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6621418PMC
June 2019
2 Reads

The Effect of Pentoxifylline on Passive Avoidance Learning and Expression of Tumor Necrosis Factor-Alpha and Caspase-3 in the Rat Hippocampus Following Lipopolysaccharide-Induced Inflammation.

Adv Biomed Res 2019 28;8:39. Epub 2019 Jun 28.

Department of Neuroscience and Addiction Studies, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran.

Background: Peripheral inflammation is effective in the development of neurodegenerative diseases. Pentoxifylline (PTX) has an inhibitory effect on inflammatory cytokines; therefore, we aimed to evaluate the effect of PTX on passive avoidance learning and the expression of tumor necrosis factor-alpha (TNF-α) and in the rat hippocampus, following systemic lipopolysaccharide (LPS) injection.

Materials And Methods: Male Wistar rats were randomly divided into five groups: control, LPS, and LPS + PTX, receiving doses of 10, 25, and 50 mg/kg of PTX, respectively. Read More

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http://dx.doi.org/10.4103/abr.abr_33_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6621342PMC
June 2019
1 Read

Frequency Distribution of Keratinophilic Dermatophyte Fungi from the Soil of Different Zones in Isfahan Using Morphological and Molecular Methods.

Adv Biomed Res 2019 28;8:38. Epub 2019 Jun 28.

Department of Parasitology and Mycology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: Dermatophytes are one of the most important etiologic agents of cutaneous infections in humans and animals. The present study aimed to study the frequency distribution of keratinophilic dermatophyte fungi using conventional and molecular methods in soil of Isfahan city.

Materials And Methods: In this study, 200 soil samples were randomly selected in three northern, southern, and central parts of Isfahan using hair-baiting technique. Read More

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http://dx.doi.org/10.4103/abr.abr_31_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6621419PMC

Internal Urethrotomy in Treatment of Female with Anatomical Bladder Outlet Obstruction.

Adv Biomed Res 2019 27;8:36. Epub 2019 May 27.

Department of Urology, Massachusetts General Hospital, Boston, Massachusetts, USA.

Background: Bladder outlet obstruction (BOO) is a relatively infrequent urologic condition in women, but can cause bothersome symptoms. In this article, transurethral incisions of the bladder neck (TUIBN) and urethra in the treatment of anatomical BOO were assessed.

Materials And Methods: A total of 23 women who referred with chronic lower urinary tract symptoms, urinary retention, and difficulty in micturition were assessed. Read More

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http://dx.doi.org/10.4103/abr.abr_200_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543863PMC
May 2019
7 Reads

A Case of Mayer-Rokitansky-Küster-Hauser Syndrome with a Fused Pancake-shaped Pelvic Kidney.

Adv Biomed Res 2019 27;8:35. Epub 2019 May 27.

Department of Radiologic Technology, Faculty of Paramedicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Mayer-Rokitansky-Küster-Hauser (MRKH) Syndrome is a female reproductive system disorder. It is characterized by a defect in the Müllerian ducts development, and it causes the absence of the uterus in variable degrees in upper vaginal hypoplasia. In addition, it is often associated with the unilateral renal dysplasia. Read More

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http://dx.doi.org/10.4103/abr.abr_97_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543865PMC
May 2019
7 Reads

Trans-scrotal Incision Approach versus Traditional Trans-scrotal Incision Orchiopexy in Children with Cryptorchidism: A Randomized Trial Study.

Adv Biomed Res 2019 27;8:34. Epub 2019 May 27.

Department of General Surgery, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: Although undescended testis (UDT) is the most prevalent malformation in male neonates, the best mode of UDT treatment remains controversial. This study aimed to compare trans-scrotal incision approach with traditional trans-scrotal incision orchiopexy in children suffering from cryptorchidism.

Materials And Methods: This single-blind randomized clinical trial was done on 100 children with UDT who needed surgery. Read More

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http://dx.doi.org/10.4103/abr.abr_26_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543866PMC
May 2019
2 Reads