Medicine (Baltimore) 2017 Aug;96(32):e7661
aSchool of Pharmacy/School of Postgraduate Studies, International Medical University, Kuala Lumpur bDepartment of Family Medicine, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Malaysia cMalaysian Research Institute on Ageing, Universiti Putra Malaysia, Serdang, Malaysia dClinical School, Department of Surgery, International Medical University, Seremban, Negeri Sembilan, Malaysia eCenter of Health Outcomes Research and Therapeutic Safety (Cohorts), School of Pharmaceutical Sciences, University of Phayao, Thailand fSchool of Pharmacy, Monash University Malaysia, Bandar Sunway, Selangor, Malaysia gCenter of Pharmaceutical Outcomes Research, Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok hUnit of Excellence on Herbal Medicine, School of Pharmaceutical Sciences, University of Phayao iDivision of Ambulatory Medicine, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand jSchool of Pharmacy, University of Wisconsin, Madison, USA kAsian Centre for Evidence Synthesis in Population, Implementation and Clinical Outcomes (PICO), Health and Well-being Cluster, Global Asia in the 21st Century (GA21) Platform, Monash University Malaysia, Bandar Sunway, Selangor, Malaysia.
: Protective effects of calcium supplementation against colorectal adenomas have been documented in systematic reviews; however, the results have not been conclusive. Our objective was to update and systematically evaluate the evidence for calcium supplementation taking into consideration the risks of systematic and random error and to GRADE the evidence.Methods
: The study comprised a systematic review with meta-analysis and trial sequential analysis (TSA) of randomized controlled trials (RCTs). Read More