87,442 results match your criteria Advanced Materials & Processes[Journal]


o-C240: a new sp3-dominated allotrope of carbon.

J Phys Condens Matter 2020 May 27. Epub 2020 May 27.

Department of Physics and Engineering Physics, University of Saskatchewan, Saskatoon, Saskatchewan, CANADA.

We report a new allotrope of carbon predicted from first principles simulations. This allotrope is formed in a simulated conversion of two-dimensional polymeric Cprecursor subjected to uniaxial compression at high temperature. The structure is made up of 240 carbon atoms in an orthorhombic unit cell (termed as-C) having a mixed/hybridization with the ratio of about 1:5. Read More

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http://dx.doi.org/10.1088/1361-648X/ab96f1DOI Listing

Circulating tumor DNA analysis of EGFR-mutant non-small cell lung cancer patients receiving osimertinib following previous tyrosine kinase inhibitor treatment.

Lung Cancer 2020 May 11;145:173-180. Epub 2020 May 11.

Amsterdam UMC, Vrije Universiteit Amsterdam, Pathology, Cancer Center Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands. Electronic address:

Objectives: Circulating tumor (ct)DNA analysis is rapidly gaining acceptance as a diagnostic tool to guide clinical management of advanced non-small cell lung cancer (NSCLC). Clinically-actionable EGFR mutations can be detected in ctDNA before or after first-line EGFR-Tyrosine Kinase Inhibitor (TKI) treatment, but data are limited for patients with a complex treatment history. This study aimed to explore the feasibility of ctDNA testing in a clinical setting of NSCLC patients receiving osimertinib as a second or third line EGFR-TKI. Read More

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http://dx.doi.org/10.1016/j.lungcan.2020.04.039DOI Listing

Ophthalmological assessment of crizotinib in advanced non-small-cell lung cancer.

Lung Cancer 2020 Apr 28;145:167-172. Epub 2020 Apr 28.

Chao Family Comprehensive Cancer Center, University of California, Irvine, Orange, CA, USA.

Objectives: During crizotinib clinical evaluation, visual disturbances, generally of grade 1 severity, were frequently reported adverse events (AE). Consequently, ophthalmologic assessments were included in a patient subgroup enrolled in PROFILE 1001 (NCT00585195), a phase 1, open-label, single-arm trial of crizotinib in patients with advanced non-small-cell lung cancer and are reported here.

Materials And Methods: At least 30 patients were required to undergo ophthalmologic assessments, including: best-corrected visual acuity (BCVA), refractive error, pupil size, slit-lamp anterior segment biomicroscopy, intraocular inflammation, intraocular pressure, retinal fundoscopic exams, fundus photography, ocular characteristics, and optical coherence tomography (OCT). Read More

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http://dx.doi.org/10.1016/j.lungcan.2020.04.010DOI Listing

Evaluation of Somatostatin and CXCR4 Receptor Expression in a Large Set of Prostate Cancer Samples Using Tissue Microarrays and Well-Characterized Monoclonal Antibodies.

Transl Oncol 2020 May 24;13(9):100801. Epub 2020 May 24.

Institute of Pharmacology and Toxicology, Jena University Hospital, Jena, Germany. Electronic address:

Background: Prostate cancer (PCa) is the most common type of cancer among men in Western countries. Despite numerous therapeutic options, few treatments are available for patients with end-stage disease. In the present study, different somatostatin receptors (SSTs) and the chemokine receptor CXCR4 were evaluated for their suitability as novel therapeutic targets in PCa. Read More

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http://dx.doi.org/10.1016/j.tranon.2020.100801DOI Listing

Circularly Polarized Photo-Luminescence from Chiral Perovskite Thin Films at Room Temperature.

ACS Nano 2020 May 27. Epub 2020 May 27.

Hybrid organic-inorganic perovskites allow the synthesis of high-quality, nanostructured semiconducting films via easily accessible solution-based techniques. This has allowed tremendous development in optoelectronic applications, primarily solar cells and light-emitting diodes. Allowed by the ease of access to nanostructure, chirality has recently been introduced in semiconducting perovskites, as a promising way to obtain advanced control of charge and spin and for developing circularly polarized light sources. Read More

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http://dx.doi.org/10.1021/acsnano.0c03628DOI Listing

Progress on Lithium Dendrite Suppression Strategies from the Interior to Exterior by Hierarchical Structure Designs.

Small 2020 May 27:e2000699. Epub 2020 May 27.

Shenzhen Geim Graphene, Center Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, 518055, P. R. China.

Lithium (Li) metal is promising for high energy density batteries due to its low electrochemical potential (-3.04 V) and high specific capacity (3860 mAh g ). However, the safety issues impede the commercialization of Li anode batteries. Read More

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http://dx.doi.org/10.1002/smll.202000699DOI Listing

Hahahahaha, Duuuuude, Yeeessss!: A two-parameter characterization of stretchable words and the dynamics of mistypings and misspellings.

PLoS One 2020 27;15(5):e0232938. Epub 2020 May 27.

Department of Mathematics and Statistics, University of Vermont, Burlington, VT, United States of America.

Stretched words like 'heellllp' or 'heyyyyy' are a regular feature of spoken language, often used to emphasize or exaggerate the underlying meaning of the root word. While stretched words are rarely found in formal written language and dictionaries, they are prevalent within social media. In this paper, we examine the frequency distributions of 'stretchable words' found in roughly 100 billion tweets authored over an 8 year period. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0232938PLOS

Switchable Full-Color Reflective Photonic Ellipsoidal Particles.

J Am Chem Soc 2020 May 27. Epub 2020 May 27.

Department of Chemistry, Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts 02139, United States.

Full-color reflective photonic ellipsoidal polymer particles, capable of a dynamic color change, are created from dendronized brush block copolymers (-BBCPs) self-assembled by solvent-evaporation from an emulsion. Surfactants composed of dendritic monomer units allow for the precise modulation of the interfacial properties of -BBCP particles to transition in shape from spheres to striped ellipsoids. Strong steric repulsions between wedge-type monomers promote rapid self-assembly of polymers into large domains (i. Read More

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http://dx.doi.org/10.1021/jacs.0c02398DOI Listing

Initiation of Intrathecal Drug Delivery Dramatically Reduces Systemic Opioid Use in Patients With Advanced Cancer.

Neuromodulation 2020 May 27. Epub 2020 May 27.

Huntsman Cancer Institute at the University of Utah, Salt Lake City, UT, USA.

Objectives: Pain is common in cancer, affecting more than 70% of patients with advanced disease. Intrathecal drug delivery systems (IDDS) are a well-established treatment for patients with refractory cancer pain, improving pain control and reducing associated side effects. To date, details of systemic opioid use before and after IDDS implant have not been reported. Read More

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http://dx.doi.org/10.1111/ner.13175DOI Listing

Intelligent image-activated cell sorting 2.0.

Lab Chip 2020 May 27. Epub 2020 May 27.

Department of Chemistry, The University of Tokyo, Tokyo 113-0033, Japan. and Japan Science and Technology Agency, Kawaguchi 332-0012, Japan and Department of Bioengineering, University of California, Los Angeles, California 90095, USA and Institute of Technological Sciences, Wuhan University, Hubei 430072, China.

The advent of intelligent image-activated cell sorting (iIACS) has enabled high-throughput intelligent image-based sorting of single live cells from heterogeneous populations. iIACS is an on-chip microfluidic technology that builds on a seamless integration of a high-throughput fluorescence microscope, cell focuser, cell sorter, and deep neural network on a hybrid software-hardware data management architecture, thereby providing the combined merits of optical microscopy, fluorescence-activated cell sorting (FACS), and deep learning. Here we report an iIACS machine that far surpasses the state-of-the-art iIACS machine in system performance in order to expand the range of applications and discoveries enabled by the technology. Read More

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http://dx.doi.org/10.1039/d0lc00080aDOI Listing

Epoxide and oxetane based liquid crystals for advanced functional materials.

Soft Matter 2020 May 27. Epub 2020 May 27.

Laboratory of Stimuli-responsive Functional Materials and Devices, Department of Chemical Engineering and Chemistry, Eindhoven University of Technology, Groene Loper 5, 5612 AE Eindhoven, The Netherlands.

Liquid crystalline elastomers (LCEs) and liquid crystalline networks (LCNs) are classes of polymers very suitable for fabricating advanced functional materials. Two main pathways to obtain LCEs and LCNs have gained the most attention in the literature, namely the two-step crosslinking of LC side-chain polymers and the photoinitiated free-radical polymerisation of acrylate LC monomers. These liquid crystal polymers have demonstrated remarkable properties resulting from their anisotropic shapes, being used in soft robotics, responsive surfaces and as photonic materials. Read More

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http://dx.doi.org/10.1039/d0sm00489hDOI Listing

A highly efficient preconcentration route for rapid and sensitive detection of endotoxin based on an electrochemical biosensor.

Analyst 2020 May 27. Epub 2020 May 27.

Key Disciplines Lab of Novel Micro-Nano Devices and System Technology & Key Laboratory of Optoelectronic Technology and Systems (Ministry of Education), College of Optoelectronic Engineering, Chongqing University, Chongqing 400044, China. and International R & D center of Micro-nano Systems and New Materials Technology, Chongqing University, Shapingba, Chongqing 400044, China.

An impedimetric aptasensor for the detection of endotoxin in a microfluidic chip was proposed, in which the Apt/AuNPs/SPCE sensing surface was fabricated in a screen-printed electrode with good biological activity and stability. The quantitative detection of endotoxin was accomplished by electrochemical impedance spectroscopy (EIS) measurement before and after exposing to samples. The impedance biosensor offers an ultrasensitive and selective detection of endotoxin down to 500 pg mL-1 with a wide linear range from 500 pg mL-1 to 200 ng mL-1. Read More

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http://dx.doi.org/10.1039/d0an00315hDOI Listing

Rapid sub-micromolar amperometric enzyme biosensing with free substrate access but without nanomaterial signalling support: oxidase-based glucose detection as a proof-of-principle example.

Chem Commun (Camb) 2020 May 27. Epub 2020 May 27.

School of Biomolecular Science and Engineering, Vidyasirimedhi Institute of Science and Technology (VISTEC), Wang Chan Valley, Rayong 21210, Thailand.

High-sensitivity electrochemical glucose biosensing has so far been possible only through incorporation of nanomaterials into the glucose oxidase-(GOx) containing polymer layer on the detector surface. Here, as a conceptionally novel simplified option, pure gelatin thin films with covalently attached GOx were used to convert platinum (Pt) disk electrodes into rapidly responding amperometric glucose probes with a sub-micromolar limit of detection. The advanced enzymatic tools are easy to make and, as is crucial for a focus on waste minimization, green and sustainable, through restriction of sensor modification to readily available economical materials. Read More

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http://dx.doi.org/10.1039/d0cc01976cDOI Listing

Predicting the phase diagram of titanium dioxide with random search and pattern recognition.

Phys Chem Chem Phys 2020 May 27. Epub 2020 May 27.

Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK. and TCM Group, Cavendish Laboratory, University of Cambridge, J. J. Thomson Avenue, Cambridge, CB3 0HE, UK and Trinity College, Trinity Street, Cambridge, CB2 1TQ, UK.

Predicting phase stabilities of crystal polymorphs is central to computational materials science and chemistry. Such predictions are challenging because they first require searching for potential energy minima and then performing arduous free-energy calculations to account for entropic effects at finite temperatures. Here, we develop a framework that facilitates such predictions by exploiting all the information obtained from random searches of crystal structures. Read More

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http://dx.doi.org/10.1039/d0cp02513eDOI Listing

Remote and Selective C(sp)-H Olefination for Sequential Regioselective Linkage of Phenanthrenes.

Org Lett 2020 May 27. Epub 2020 May 27.

Hubei Collaborative Innovation Center for Advanced Chemical Materials, Ministry of Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules and College of Chemistry and Chemical Engineering, Hubei University, Wuhan 430062, China.

Biphenylcarboxylic acid with two competing C(sp)-H sites was designed for site selective C(sp)-H functionalization by developing carboxylic acids assisted remote and selective olefination via 7-membered palladacycle. Mechanism investigation and DFT calculations reveal a kinetics-determined process, which could be utilized to explore a variety of remote site selectivity. The practicability of this method was highlighted by the precise construction of phenathrene under sequential site selectivity. Read More

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http://dx.doi.org/10.1021/acs.orglett.0c01208DOI Listing

Identifying Dense NiSe /CoSe Heterointerfaces Coupled with Surface High-Valence Bimetallic Sites for Synergistically Enhanced Oxygen Electrocatalysis.

Adv Mater 2020 May 27:e2000607. Epub 2020 May 27.

School of Materials Science and Engineering, Key Laboratory of Advanced Ceramics and Machining Technology of the Ministry of Education, Tianjin Key Laboratory of Composite and Functional Materials, Tianjin University, Tianjin, 300072, P. R. China.

Constructing heterostructures with abundant interfaces is essential for integrating the multiple functionalities in single entities. Herein, the synthesis of NiSe /CoSe heterostructures with different interfacial densities via an innovative strategy of successive ion injection is reported. The resulting hybrid electrocatalyst with dense heterointerfaces exhibits superior electrocatalytic properties in an alkaline electrolyte, superior to other benchmarks and precious metal catalysts. Read More

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http://dx.doi.org/10.1002/adma.202000607DOI Listing

A General Hypoxia-Responsive Molecular Container for Tumor-Targeted Therapy.

Adv Mater 2020 May 27:e1908435. Epub 2020 May 27.

College of Chemistry, Key Laboratory of Functional Polymer Materials (Ministry of Education), State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin, 300071, China.

Enhanced drug delivery can improve the therapeutic efficacy of drugs and help overcome side effects. However, many reported drug-delivery systems are too complex and irreproducible for practical use. In this work, the design of a hypoxia-responsive molecular container based on calixarene, called CAC4A, which presents a significant advance in practical, hypoxia-targeted drug-delivery, is reported. Read More

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http://dx.doi.org/10.1002/adma.201908435DOI Listing

Designing Outside the Box: Unlocking the Geometric Freedom of Melt Electrowriting using Microscale Layer Shifting.

Adv Mater 2020 May 27:e2001874. Epub 2020 May 27.

Department of Functional Materials in Medicine and Dentistry and Bavarian Polymer Institute, University Hospital of Würzburg, Pleicherwall 2, Würzburg, 97070, Germany.

Melt electrowriting, a high-resolution additive manufacturing technology, has so far been developed with vertical stacking of fiber layers, with a printing trajectory that is constant for each layer. In this work, microscale layer shifting is introduced through deliberately offsetting the printing trajectory for each printed layer. Inaccuracies during the printing of sinusoidal walls are corrected via layer shifting, resulting in accurate control of their geometry and mechanical properties. Read More

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http://dx.doi.org/10.1002/adma.202001874DOI Listing

Emerging trends in porous materials for CO capture and conversion.

Chem Soc Rev 2020 May 27. Epub 2020 May 27.

Global Innovative Centre for Advanced Nanomaterials, Faculty of Engineering & Built Environment, University of Newcastle, Callaghan, 2308, Australia.

The presence of an excessive concentration of CO2 in the atmosphere needs to be curbed with suitable measures including the reduction of CO2 emissions at stationary point sources such as power plants through carbon capture technologies and subsequent conversion of the captured CO2 into non-polluting clean fuels/chemicals using photo and/or electrocatalytic pathways. Porous materials have attracted much attention for carbon capture and in the recent past; they have witnessed significant advancements in their design and implementation for CO2 capture and conversion. In this context, the emerging trends in major porous adsorbents such as MOFs, zeolites, POPs, porous carbons, and mesoporous materials for CO2 capture and conversion are discussed. Read More

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http://dx.doi.org/10.1039/d0cs00075bDOI Listing

Balancing connectivity with function in silver(i) networks of pyridyltriazole (tzpa) ligands results in the formation of a metallogel.

Dalton Trans 2020 May 27. Epub 2020 May 27.

School of Chemistry and Trinity Biomedical Sciences Institute, The University of Dublin, Trinity College Dublin, Dublin 2, Ireland. and The AMBER (Advanced Materials and BioEngineering Research) Centre, Trinity College Dublin, The University of Dublin, Dublin 2, Ireland.

A new flexible and divergent 1,2,3-triazol-4-yl-picolinamide (tzpa) ligand 2 and the half-equivalent model ligand 1, both functionalised with pendant 3-pyridyl groups, are reported and their coordination behaviour with silver(i) ions is explored, both in the crystalline phase and through the formation of a supramolecular metallogel. The self-assembly of tzpa ligand 1 with AgCF3SO3 resulted in the formation of a 1D coordination polymer, binding in a bidentate fashion through the pyridyl and triazole nitrogen atoms of the tzpa binding site and a pendant pyridyl nitrogen atom of an adjacent ligand. Doubling the number of metal binding sites in ligand 2, while retaining the same metal binding domain, gives rise to the formation of a supramolecular metallogel on reaction with AgBF4 at 5 wt% in MeCN, possessing self-healing properties. Read More

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http://dx.doi.org/10.1039/d0dt01421dDOI Listing

Conformational equilibrium of MinE regulates the allowable concentration ranges of a protein wave for cell division.

Nanoscale 2020 May 27. Epub 2020 May 27.

Department of Biosciences & Informatics, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan.

The Min system for determining the cell division position at the center in bacteria has a unique character that uses a protein wave (Min wave) that emerges from its components (MinD and MinE). The Min wave emerges under the coupling of chemical reactions and molecular diffusions of MinDE and appears when the concentrations of MinD and MinE are similar. However, the nanoscale mechanism to determine their concentration ranges has remained elusive. Read More

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http://dx.doi.org/10.1039/d0nr00242aDOI Listing

Surface modification of all-inorganic halide perovskite nanorods by a microscale hydrophobic zeolite for stable and sensitive laser humidity sensing.

Nanoscale 2020 May 27. Epub 2020 May 27.

Department of Electrical and Electronic Engineering, Southern University of Science and Technology, Shenzhen, Guangdong 518055, P. R. China.

Perovskite materials are very sensitive to the environment which is beneficial for humidity sensing. However, the existing illuminating humidity sensor has low luminous efficiency and sensitivity. Besides, the stability of perovskite materials remains a key issue to be resolved. Read More

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http://dx.doi.org/10.1039/d0nr01889aDOI Listing

Self-aligned 3D microlenses in a chip fabricated with two-photon stereolithography for highly sensitive absorbance measurement.

Lab Chip 2020 May 27. Epub 2020 May 27.

Institute of Environmental Engineering, ETH Zürich, Zürich 8093, Switzerland. and Laboratory for Advanced Analytical Technologies, Empa, Swiss Federal Laboratories for Materials Science and Technology, Dübendorf 8600, Switzerland.

Absorbance measurement is a widely used method to quantify the concentration of an analyte. The integration of absorbance analysis in microfluidic chips could significantly reduce the sample consumption and contribute to the system miniaturization. However, the sensitivity and limit of detection (LoD) of analysis in microfluidic chips with conventional configuration need improvements due to the limited optical pathway and unregulated light propagation. Read More

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http://dx.doi.org/10.1039/d0lc00235fDOI Listing

Mesoporous carbon host material for stable lithium metal anode.

Nanoscale 2020 May 27. Epub 2020 May 27.

Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea.

Lithium (Li) metal is a promising anode material for next-generation batteries because of its low standard reduction potential (-3.04 V vs. SHE) and high specific capacity (3860 mA h g-1). Read More

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http://dx.doi.org/10.1039/d0nr02258fDOI Listing

Surfactant and oil formulations for monodisperse droplet emulsion PCR.

Lab Chip 2020 May 27. Epub 2020 May 27.

Department of Materials Science and Engineering, College of Engineering, Peking University, Beijing 100871, China. and Biomedical Pioneering Innovation Center (BIOPIC), Beijing Advanced Innovation Center for Genomics (ICG), Peking University, Beijing 100871, China and Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China and College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China and Institute for Cell Analysis, Shenzhen Bay Laboratory, Guangdong 518132, China and Chinese Institute for Brain Research, Beijing 102206, China.

Emulsion PCR has become a popular and widely applied method in biological research and clinical diagnostics to provide evenly amplified products and perform highly quantitative counting of target sequences. However, there is still a lack of information to support further development of appropriate water-in-oil emulsion formulations, which need to be both thermally and mechanically stable for digital amplification reactions. Here, we present a systematic survey of the oil and surfactant components of stable monodisperse w/o emulsions suitable for use with our previously developed micro-capillary array (MiCA)-based centrifugal emulsion generation method. Read More

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http://dx.doi.org/10.1039/d0lc00052cDOI Listing

Driving force to detect Alzheimer's disease biomarkers: application of a thioflavine T@Er-MOF ratiometric fluorescent sensor for smart detection of presenilin 1, amyloid β-protein and acetylcholine.

Analyst 2020 May 27. Epub 2020 May 27.

Key Laboratory of Inorganic-Organic Hybrid Functional Material Chemistry (Tianjin Normal University), Ministry of Education, Tianjin Key Laboratory of Structure and Performance for Functional Molecule, College of Chemistry, Tianjin Normal University, 393 Binshui West Road, Tianjin 300387, PR China. and Key Laboratory of Advanced Energy Materials Chemistry (Ministry of Education), Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), College of Chemistry, Nankai University, Tianjin 300071, PR China.

Currently, the highly sensitive detection of Alzheimer's Disease (AD) biomarkers, namely presenilin 1, amyloid β-protein (Aβ), and acetylcholine (ACh), is vital to helping us prevent and diagnose AD. In this work, a novel metal-organic framework [Er(L)(DMF)1.27]n (Er-MOF) (H3L = terphenyl-3,4'',5-tricarboxylic acid) has been synthesized by solvothermal and ultrasonic methods. Read More

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http://dx.doi.org/10.1039/d0an00440eDOI Listing

Phase Transformation of a KGeF Polymorph for Phosphors Driven by a Simple Precipitation-Dissolution Equilibrium and Ion Exchange.

Inorg Chem 2020 May 27. Epub 2020 May 27.

School of Advanced Manufacturing Technologies, National Research Tomsk Polytechnic University, Tomsk 634050, Russia.

Tuning crystal phase transformations is very important for obtaining polymorphs for phosphors with the ideal optical properties and stability. Mn-doped KGeF (KGF) is a typical polymorphic phosphor, but the thermodynamic and kinetic mechanism of its phase transformation is still unclear. Herein, the phase transformation of polymorphs varying from 6 KGF and trigonal KGF to 6 Si-doped KGF is realized by introducing the synergistic action of an HF solution and Si ions. Read More

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http://dx.doi.org/10.1021/acs.inorgchem.0c00701DOI Listing

Occupational Exposure and Risk Assessment of Formaldehyde in the Pathology Departments of Hospitals.

Asian Pac J Cancer Prev 2020 May 1;21(5):1303-1309. Epub 2020 May 1.

Department of Occupational Health, School of Health, Guilan University of Medical Sciences, Rasht, Iran.

Background And Objective: Exposure to formaldehyde has adverse effects on health both acutely and over the long term (e.g., carcinogenicity). Read More

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http://dx.doi.org/10.31557/APJCP.2020.21.5.1303DOI Listing

Inhibitory Effect of Eco-Friendly Naturally Synthesized Silver Nanoparticles from the Leaf Extract of Medicinal Detarium microcarpum Plant on Pancreatic and Cervical Cancer Cells.

Asian Pac J Cancer Prev 2020 May 1;21(5):1247-1252. Epub 2020 May 1.

School of Biological Sciences, Universiti Sains Malaysia, 11800 USM, Pulau Pinang, Malaysia.

Background: Recently, nanoparticle synthesis by eco-friendly methods has received tremendous attention due to the method advantages and also because of the application of the nanoparticles in cancer research. Therefore, in this study, we synthesized silver nanoparticles from Detarium microcarpum leaf phytochemicals and evaluated its inhibitory effect on pancreatic and cervical cancer cells.

Materials And Methods: Silver nanoparticles (dAgNps) were synthesized by reacting phytochemicals of D. Read More

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http://dx.doi.org/10.31557/APJCP.2020.21.5.1247DOI Listing

Characterization of PfiT/PfiA toxin-antitoxin system of Pseudomonas aeruginosa that affects cell elongation and prophage induction.

Environ Microbiol 2020 May 26. Epub 2020 May 26.

The Mina and Everard Goodman Faculty of Life Sciences and the Institute of Nanotechnology and Advanced Materials, Bar-Ilan University, Ramat Gan, Israel.

Toxin-antitoxin (TA) systems are small genetic modules usually consisting of two elements - a toxin and an antitoxin. The abundance of TA systems among various bacterial strains may indicate an important evolutionary role. Pseudomonas aeruginosa, which can be found in a variety of niches in nature, is an opportunistic pathogen for various hosts. Read More

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http://dx.doi.org/10.1111/1462-2920.15102DOI Listing

Chemical Bonding in Chalcogenides: The Concept of Multicenter Hyperbonding.

Adv Mater 2020 May 27:e2000340. Epub 2020 May 27.

Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.

The precise nature of chemical-bonding interactions in amorphous, and crystalline, chalcogenides is still unclear due to the complexity arising from the delocalization of bonding, and nonbonding, electrons. Although an increasing degree of electron delocalization for elements down a column of the periodic table is widely recognized, its influence on chemical-bonding interactions, and on consequent material properties, of chalcogenides has not previously been comprehensively understood from an atomistic point of view. Here, a chemical-bonding framework is provided for understanding the behavior of chalcogenides (and, in principle, other lone-pair materials) by studying prototypical telluride nonvolatile-memory, "phase-change" materials (PCMs), and related chalcogenide compounds, via density-functional-theory molecular-dynamics (DFT-MD) simulations. Read More

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http://dx.doi.org/10.1002/adma.202000340DOI Listing

Does low body mass index constitute a risk of damage to the soft tissues during reaming for proximal femoral nailing? a cadaveric study.

Eur J Orthop Surg Traumatol 2020 May 26. Epub 2020 May 26.

Kanuni Sultan Suleyman Training and Research Hospital, Saglik Bilimleri University, Atakent Mh. Turgut Özal Blv. No:46/1, 34303, Kucukcekmece, Istanbul, Turkey.

Background: The purpose of this cadaveric study was to evaluate the damage to the gluteus medius muscle, tendon and superior gluteal nerve in low BMI patients during the reaming of the greater trochanter tip for proximal femoral nailing.

Materials And Methods: The study used 19 femurs of 10 fresh femur intact cadavers [mean BMI: 22.79 (17. Read More

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http://dx.doi.org/10.1007/s00590-020-02707-1DOI Listing

Intelligent Bimetallic Nanoagents as Reactive Oxygen Species Initiator System for Effective Combination Phototherapy.

Front Bioeng Biotechnol 2020 8;8:423. Epub 2020 May 8.

Biomaterials Research Center, School of Biomedical Engineering, Southern Medical University, Guangzhou, China.

Phototherapy is a promising oncotherapy method. However, there are various factors greatly restricted phototherapy development, including poor tumor-specific accumulation, the hypoxia in solid tumor, and the systemic phototoxicity of photosensitizer. Herein, a tumor microenvironment (TME)-responsive intelligent bimetallic nanoagents (HSA-Pd-Fe-Ce6 NAs) composed of human serum albumin (HSA), palladium-iron (Pd-Fe) bimetallic particles, and chlorin e6 (Ce6) was designed for effective combination phototherapy. Read More

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http://dx.doi.org/10.3389/fbioe.2020.00423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225307PMC

Controllable skyrmion chirality in ferroelectrics.

Sci Rep 2020 May 26;10(1):8657. Epub 2020 May 26.

Materials Science Division, Argonne National Laboratory, 9700S. Cass Avenue, Argonne, Illinois, 60637, USA.

Chirality, an intrinsic handedness, is one of the most intriguing fundamental phenomena in nature. Materials composed of chiral molecules find broad applications in areas ranging from nonlinear optics and spintronics to biology and pharmaceuticals. However, chirality is usually an invariable inherent property of a given material that cannot be easily changed at will. Read More

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http://dx.doi.org/10.1038/s41598-020-65291-8DOI Listing

Phase estimation algorithm for the multibeam optical metrology.

Sci Rep 2020 May 26;10(1):8715. Epub 2020 May 26.

Moscow Institute of Physics and Technology, 141700, Institutskii Per. 9, Dolgoprudny, Moscow Distr., Russian Federation.

Unitary Fourier transform lies at the core of the multitudinous computational and metrological algorithms. Here we show experimentally how the unitary Fourier transform-based phase estimation protocol, used namely in quantum metrology, can be translated into the classical linear optical framework. The developed setup made of beam splitters, mirrors and phase shifters demonstrates how the classical coherence, similarly to the quantum coherence, poses a resource for obtaining information about the measurable physical quantities. Read More

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http://dx.doi.org/10.1038/s41598-020-65466-3DOI Listing

Understanding the interface interaction between USi fuel and SiC cladding.

Nat Commun 2020 May 26;11(1):2621. Epub 2020 May 26.

Nuclear Engineering Program, University of South Carolina, Columbia, SC, 29208, USA.

Triuranium disilicide (USi) fuel with silicon carbide (SiC) composite cladding is being considered as an advanced concept/accident tolerant fuel for light water reactors thus, understanding their chemical compatibility under operational and accident conditions is paramount. Here we provide a comprehensive view of the interaction between USi and SiC by utilizing density functional theory calculations supported by diffusion couple experiments. From the calculated reaction energies, we demonstrate that triuranium pentasilicide (USi), uranium carbide (UC), USiC, and uranium silicide (USi) phases can form at the interface. Read More

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http://dx.doi.org/10.1038/s41467-020-16435-xDOI Listing

Electrical switching between exciton dissociation to exciton funneling in MoSe/WS heterostructure.

Nat Commun 2020 May 26;11(1):2640. Epub 2020 May 26.

Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA.

The heterostructure of monolayer transition metal dichalcogenides (TMDCs) provides a unique platform to manipulate exciton dynamics. The ultrafast carrier transfer across the van der Waals interface of the TMDC hetero-bilayer can efficiently separate electrons and holes in the intralayer excitons with a type II alignment, but it will funnel excitons into one layer with a type I alignment. In this work, we demonstrate the reversible switch from exciton dissociation to exciton funneling in a MoSe/WS heterostructure, which manifests itself as the photoluminescence (PL) quenching to PL enhancement transition. Read More

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http://dx.doi.org/10.1038/s41467-020-16419-xDOI Listing

Tuning molecular emission of organic emitters from fluorescence to phosphorescence through push-pull electronic effects.

Nat Commun 2020 May 26;11(1):2617. Epub 2020 May 26.

Department of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Institute for Advanced Study, The Hong Kong University of Science and Technology, Clear Water Bay, 999077, Kowloon, Hong Kong, China.

Organic emitters with persistent phosphorescence have shown potential application in optoelectronic devices. However, rational design and phosphorescence tuning are still challenging. Here, a series of metal-free luminophores without heavy atoms and carbonyl groups from commercial/lab-synthesized carbazole and benzene were synthesized to realize tunable molecular emission from fluorescence to phosphorescence by simply substituent variation. Read More

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http://dx.doi.org/10.1038/s41467-020-16412-4DOI Listing

Tuning the interfacial spin-orbit coupling with ferroelectricity.

Nat Commun 2020 May 26;11(1):2627. Epub 2020 May 26.

State Key Laboratory of Surface Physics and Department of Physics, Fudan University, 200433, Shanghai, China.

Detection and manipulation of spin current lie in the core of spintronics. Here we report an active control of a net spin Hall angle, θ(net), in Pt at an interface with a ferroelectric material PZT (PbZrTiO), using its ferroelectric polarization. The spin Hall angle in the ultra-thin Pt layer is measured using the inverse spin Hall effect with a pulsed tunneling current from a ferromagnetic LaSrMnO electrode. Read More

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http://dx.doi.org/10.1038/s41467-020-16401-7DOI Listing

The multi-faceted mechano-bactericidal mechanism of nanostructured surfaces.

Proc Natl Acad Sci U S A 2020 May 26. Epub 2020 May 26.

School of Science, College of Science, Engineering and Health, RMIT University, Melbourne, VIC 3000, Australia.

The mechano-bactericidal activity of nanostructured surfaces has become the focus of intensive research toward the development of a new generation of antibacterial surfaces, particularly in the current era of emerging antibiotic resistance. This work demonstrates the effects of an incremental increase of nanopillar height on nanostructure-induced bacterial cell death. We propose that the mechanical lysis of bacterial cells can be influenced by the degree of elasticity and clustering of highly ordered silicon nanopillar arrays. Read More

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http://dx.doi.org/10.1073/pnas.1916680117DOI Listing

Surgical training in gynecologic oncology: Past, present, future.

Gynecol Oncol 2020 May 23. Epub 2020 May 23.

Division of Gynecologic Oncology, Medical University of South Carolina, 86 Jonathan Lucus Street, Charleston, SC 29425, United States of America. Electronic address:

The purpose of this paper is to review the surgical care related to training in gynecologic oncology, from past, present and future perspectives. A marked decline in the incidence of cervical cancer as well as improvements in radiation therapy have led to a reduction in the numbers of radical hysterectomies and exenterations being performed. Utilization of neoadjuvant chemotherapy is reducing the extent of cytoreductive operations, including intestinal surgery. Read More

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http://dx.doi.org/10.1016/j.ygyno.2020.05.006DOI Listing

Label-free discrimination of glioma brain tumors in different stages by surface enhanced Raman scattering.

Talanta 2020 Aug 8;216:120983. Epub 2020 Apr 8.

Jiangsu Key Laboratory of Advanced Laser Materials and Devices, School of Physics and Electronic Engineering, Jiangsu Normal University, Xuzhou, Jiangsu, China. Electronic address:

According to the WHO classification criteria, the most common intracranial tumor gliomas can be divided into four grades based on their symptoms. Among them, Grade Ⅰ and Grade II are low-grade gliomas, and Grade III and Grade IV are high-grade gliomas. Because gliomas have a high lethal rate, they have received widespread attention in the medical field. Read More

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http://dx.doi.org/10.1016/j.talanta.2020.120983DOI Listing

GreenLight XPS 180-W Laser Vaporization of Prostate in High-Risk Elderly Patients: A Single-Center Experience.

Photobiomodul Photomed Laser Surg 2020 May 26. Epub 2020 May 26.

Department of Urology, the Second Affiliated Hospital of Soochow University, Suzhou 215004, Jiangsu, China.

To evaluate the safety and efficacy of GreenLight XPS 180-W laser photoselective vaporization of the prostate (PVP) in high-risk elderly patients with benign prostatic hyperplasia. This retrospective study included 150 elderly patients with enlarged prostate glands (>40 mL) receiving 180-W photoselective vaporization at our department between January 2016 and October 2018. All patients were of advanced age (>80 years) and included those at higher risk of bleeding and cardiopulmonary disease. Read More

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http://dx.doi.org/10.1089/photob.2019.4735DOI Listing

Distributions of Potential and Contact-Induced Charges in Conventional Organic Photovoltaics.

Authors:
Kouki Akaike

Materials (Basel) 2020 May 24;13(10). Epub 2020 May 24.

National Institute of Advanced Industrial Science and Technology, Tsukuba 305-8565, Japan.

The interfaces of dissimilar materials play central roles in photophysical events in organic photovoltaics (OPVs). Depth profiles of electrostatic potential and contact-induced charges determine the energy-level lineup of the frontier orbitals at electrode/organic and organic heterointerfaces. They are critical for the elementary processes in an OPV cell, such as generation and diffusion of free carriers. Read More

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http://dx.doi.org/10.3390/ma13102411DOI Listing

Reduced Graphene Oxide Nanosheet-Decorated Copper Oxide Nanoparticles: A Potent Antifungal Nanocomposite against Fusarium Root Rot and Wilt Diseases of Tomato and Pepper Plants.

Nanomaterials (Basel) 2020 May 24;10(5). Epub 2020 May 24.

Mycology and Disease Survey Research Department, Plant Pathology Research Institute, Agricultural Research Center, Giza 12619, Egypt.

Sustainable use of nanotechnology in crop protection requires an understanding of the plant's life cycle, potential toxicological impacts of nanomaterials and their mechanism of action against the target pathogens. Herein, we show some properties of a candidate antifungal nanocomposite made from copper oxide (CuO; otherwise an essential soil nutrient) nanoparticles (NPs), with definite size and shape, decorating the surface of reduced graphene oxide (rGO) nanosheets. The successful preparation of the rGO-CuO NPs was confirmed by spectroscopic and microscopic analyses, and its antifungal activity against wild strains of affecting tomato and pepper plants was successfully confirmed. Read More

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http://dx.doi.org/10.3390/nano10051001DOI Listing

Current Status and Prospects of Polymer Powder 3D Printing Technologies.

Materials (Basel) 2020 May 23;13(10). Epub 2020 May 23.

Shenzhen Key Laboratory for Additive Manufacturing of High performance Materials, Department of Mechanical and Energy Engineering, Southern University of Science and Technology, Shenzhen 518055, China.

3D printing technology, which greatly simplifies the manufacturing of complex parts by a two-dimensional layer-upon-layer process, has flourished in recent years. As one of the most advanced technology, polymer powder 3D printing has many advantages such as high materials utilization rate, free of support structure, great design freedom, and large available materials, which has shown great potential and prospects in various industry applications. With the launch of the Multi jet Fusion system from HP, polymer powder 3D printing has been attracting more attention from industries and researchers. Read More

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http://dx.doi.org/10.3390/ma13102406DOI Listing

Complementary SEM-AFM of Swelling Bi-Fe-O Film on HOPG Substrate.

Materials (Basel) 2020 May 23;13(10). Epub 2020 May 23.

Central European Institute of Technology BUT, Purkyňova 123, 612 00 Brno, Czech Republic.

The objective of this work is to study the delamination of bismuth ferrite prepared by atomic layer deposition on highly oriented pyrolytic graphite (HOPG) substrate. The samples' structures and compositions are provided by XPS, secondary ion mass spectrometry (SIMS) and Raman spectroscopy. The resulting films demonstrate buckling and delamination from the substrates. Read More

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http://dx.doi.org/10.3390/ma13102402DOI Listing

Thermotropic Liquid-Crystalline and Light-Emitting Properties of Bis(4-aalkoxyphenyl) Viologen Bis(triflimide) Salts.

Molecules 2020 May 23;25(10). Epub 2020 May 23.

Division of Research, University at Albany, Albany, NY 12222, USA.

A series of bis(4-alkoxyphenyl) viologen bis(triflimide) salts with alkoxy chains of different lengths were synthesized by the metathesis reaction of respective bis(4-alkoxyphenyl) viologen dichloride salts, which were in turn prepared from the reaction of Zincke salt with the corresponding 4-n-alkoxyanilines, with lithium triflimide in methanol. Their chemical structures were characterized by H and C nuclear magnetic resonance spectra and elemental analysis. Their thermotropic liquid-crystalline (LC) properties were examined by differential scanning calorimetry, polarizing optical microscopy, and variable temperature X-ray diffraction. Read More

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http://dx.doi.org/10.3390/molecules25102435DOI Listing

The Preliminary Exploration of Micro-Friction Stir Welding Process and Material Flow of Copper and Brass Ultra-Thin Sheets.

Materials (Basel) 2020 May 22;13(10). Epub 2020 May 22.

School of Material Science and Engineering, Lanzhou University of Technology, Lanzhou 730050, China.

In the friction stir welding (FSW) of ultra-thin dissimilar metal sheets, different physical material properties, the reduction of plastic metal in the weld zone, and insufficient plastic metal flow lead to poor weld seam shapes and joint qualities. Therefore, it is necessary to study the flow behavior during the FSW of ultrathin sheets. In this study, micro friction stir welding (μFSW) was conducted and analyzed for the butt welding of 0. Read More

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http://dx.doi.org/10.3390/ma13102401DOI Listing

Influence of Phosphorus Slag on Physical and Mechanical Properties of Cement Mortars.

Materials (Basel) 2020 May 22;13(10). Epub 2020 May 22.

Research and Development Center, Baosen (Shanghai) Environmental Engineering Co., Ltd., Shanghai 200439, China.

Influences of phosphorus slag from 10% to 50% (by mass) on the setting time and the water requirement of the normal consistency of cement pastes, flowability, resistance to carbonation, and the compressive strength of cement mortars were investigated. The physical activation by improving fineness and the chemical activation by adding the chemical activator were evaluated by the compressive strength of cement mortars with 30% by mass of phosphorus slag. Hydration heat, X-ray diffraction, and scanning electron microscopy were used to study the microstructure of cement pastes and mortars with 30% by mass of phosphorus slag and the chemical activator. Read More

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http://dx.doi.org/10.3390/ma13102390DOI Listing