676,532 results match your criteria Advanced Composites Letters[Journal]

Bioelectricity production from sweat-activated germination of bacterial endospores.

Biosens Bioelectron 2021 May 3;186:113293. Epub 2021 May 3.

Bioelectronics & Microsystems Laboratory, Department of Electrical & Computer Engineering, State University of New York at Binghamton, Binghamton, NY, 13902, USA; Center for Research in Advanced Sensing Technologies & Environmental Sustainability (CREATES), State University of New York at Binghamton, Binghamton, NY, 13902, USA. Electronic address:

A microbial fuel cell is created that uses a bacterium's natural ability to revive from dormancy to provide on-demand power for next-generation wearable applications. In adverse conditions, Bacillus subtilis responds by becoming endospores that serve as a dormant biocatalyst embedded in a skin-mountable paper-based microbial fuel cell. When activated by nutrient-rich human sweat, the germinating bacteria produce enough electricity to operate small devices, such as the calculator that we operated to test our methodology. Read More

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Conducting polymer hydrogels as a sustainable platform for advanced energy, biomedical and environmental applications.

Sci Total Environ 2021 Apr 30;786:147430. Epub 2021 Apr 30.

Key Laboratory of Jiangxi Province for Persistent Pollutants Control and Resources Recycle, Nanchang Hangkong University, Nanchang 330063, PR China; National-Local Joint Engineering Research Center of Heavy Metals Pollutants Control and Resource Utilization, Nanchang Hangkong University, Nanchang 330063, PR China. Electronic address:

Environmentally friendly polymeric materials and derivative technologies play increasingly important roles in the sustainable development of our modern society. Conducting polymer hydrogels (CPHs) synergizing the advantageous characteristics of conventional hydrogels and conducting polymers are promising to satisfy the requirements of environmental sustainability. Beyond their use in energy and biomedical applications that require exceptional mechanical and electrical properties, CPHs are emerging as promising contaminant adsorbents owing to their porous network structure and regulable functional groups. Read More

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Synergy between autotrophic denitrification and Anammox driven by FeS in a fluidized bed bioreactor for advanced nitrogen removal.

Chemosphere 2021 Apr 30;280:130726. Epub 2021 Apr 30.

School of Environment and Energy, South China University of Technology, Guangzhou, 510006, PR China. Electronic address:

On the basis of the metabolic synergy between autotrophic denitrification (AuDen) and anaerobic ammonium oxidation (Anammox), the feasibility of a novel ferrous sulfide (FeS)-driven AuDen and Anammox coupled system (FS-DADAS) was investigated. The nitrogen removal performance of FS-DADAS was investigated in a lab-scale fluidized bed bioreactor fed with synthetic wastewater containing NH-N and NO-N. The results of long-term operation (120 days) demonstrated the promising performance of the system with 100% NO-N removal and NH-N concentrations lower than 8. Read More

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Polycyclic aromatic hydrocarbons in airborne particulate matter samples from Hanoi, Vietnam: Particle size distribution, aryl hydrocarbon ligand receptor activity, and implication for cancer risk assessment.

Chemosphere 2021 Apr 30;280:130720. Epub 2021 Apr 30.

Centre for Environmental Technology and Sustainable Development (CETASD), University of Science, Vietnam National University, Hanoi, 334 Nguyen Trai, Hanoi, 11400, Viet Nam. Electronic address:

Concentrations and profiles of unsubstituted and methylated polycyclic aromatic hydrocarbons (PAHs and Me-PAHs) were analyzed in airborne particulate matter (PM) samples collected from high-traffic roads in Hanoi urban area. Levels of PAHs and Me-PAHs ranged from 210 to 660 (average 420) ng/m in total PM, and these pollutants were mainly associated with fine particles (PM) rather than coarser ones (PM and PM). Proportions of high-molecular-weight compounds (i. Read More

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Graphene oxide nanocomposites based room temperature gas sensors: A review.

Chemosphere 2021 Apr 29;280:130641. Epub 2021 Apr 29.

Department of Physics, VIT-AP University, Amaravati, Guntur, 522501, Andhra Pradesh, India. Electronic address:

Over the last few decades, various volatile organic compounds (VOCs) have been widely used in the processing of building materials and this practice adversely affected the environment i.e. both indoor and outdoor air quality. Read More

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Targeting the transcription cycle and RNA processing in cancer treatment.

Curr Opin Pharmacol 2021 May 5;58:69-75. Epub 2021 May 5.

Center for Research on Reproduction & Women's Health, University of Pennsylvania, Philadelphia, PA, USA; Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, PA, USA. Electronic address:

The transcriptional program and RNA splicing machinery are highly and frequently dysregulated in human cancers due to genomic and epigenomic alterations during tumorigenesis. This leads to cancer-specific dependencies on components of the transcriptional program and RNA splicing machinery, providing alternative and targetable 'Achilles' heels' for cancer treatment in the clinic. To target these vulnerabilities in cancer cells, potent and specific transcriptional CDK inhibitors and chemical compounds that impair splicing have been developed and evaluated in preclinical cancer models. Read More

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Gouty tophus presenting as an anterior cruciate ligament mass in the knee: Case report and brief review of relevant literature.

Int J Surg Case Rep 2021 Apr 27;82:105920. Epub 2021 Apr 27.

Michael Garron Hospital, Toronto, ON, Canada; University of Toronto, Toronto, ON, Canada.

Introduction And Importance: Tophacious gout presenting at the anterior cruciate ligament (ACL) is extremely rare and difficult to differentiate from other intraarticular pathology. This is mainly due to conventional diagnostic tools, such as MRI, producing ambiguous results versus pigmented villonodular synovitis (PVNS) and ganglion cysts.

Case Presentation: Here we report an individual in their late-20s with a gouty tophus located at the origin of the ACL in the knee. Read More

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Metal organic framework-derived C-doped ZnO/TiO nanocomposite catalysts for enhanced photodegradation of Rhodamine B.

J Colloid Interface Sci 2021 Apr 1;599:566-576. Epub 2021 Apr 1.

Integrated Composites Laboratory (ICL), Department of Chemical & Biomolecular Engineering, University of Tennessee, Knoxville, TN 37996, USA. Electronic address:

A series of C-doped ZnO/TiO composites with various molar ratios of ZnO to TiO were synthesized by one-step controllable pyrolysis of Zn/Ti bimetallic metal-organic frameworks (Zn/Ti-MOF). The Zn/Ti-MOF was prepared using a facile microwave hydrothermal method. Electron microscopic analysis proved that the composites presented regularity cubic morphology with an edge length of about 1 μm and the C atoms were successfully doped into ZnO/TiO composites. Read More

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Distribution, behaviour, bioavailability and remediation of poly- and per-fluoroalkyl substances (PFAS) in solid biowastes and biowaste-treated soil.

Environ Int 2021 May 5;155:106600. Epub 2021 May 5.

Department of Plant, Soil and Microbial Sciences, Michigan State University, East Lansing, MI 48824, USA; Department of Agronomy, Kansas State University, Manhattan, KS 66506, USA.

Aqueous film-forming foam, used in firefighting, and biowastes, including biosolids, animal and poultry manures, and composts, provide a major source of poly- and perfluoroalkyl substances (PFAS) input to soil. Large amounts of biowastes are added to soil as a source of nutrients and carbon. They also are added as soil amendments to improve soil health and crop productivity. Read More

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Advanced eco-friendly UV spectrophotometric approach for resolving overlapped spectral signals of antihypertensive agents in their binary and tertiary pharmaceutical dosage form.

Spectrochim Acta A Mol Biomol Spectrosc 2021 Apr 19;258:119855. Epub 2021 Apr 19.

Pharmaceutical Chemistry Department, Faculty of Pharmacy, Egyptian Russian University, Badr City 11829, Cairo, Egypt. Electronic address:

Cardiovascular disorders are among the foremost causes of death worldwide, especially hypertension, a silent killer syndrome that requires multiple drug therapy for proper management. This work presents novel and green spectrophotometric methods for the concurrent analysis of Amlodipine (AML), Telmisartan (TEL), Hydrochlorothiazide (HCTZ), and Chlorthalidone (CLO) in their pharmaceutical dosage form. The suggested methods were Fourier-self deconvolution, amplitude factor, and first derivative methods developed and validated for the simultaneous determination of a tertiary mixture of AML, TEL, and HCTZ in TELVAS 3D 80 mg tablet and a binary mixture of TEL and CLO in TELMIKIND-CT 40 tablets. Read More

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Hydrothermally-altered feldspar as an environmentally-friendly technology to promote heavy metals immobilization: Batch studies and application in smelting-affected soils.

J Environ Manage 2021 May 5;291:112711. Epub 2021 May 5.

School of Agricultural Sciences, Department of Soil Science, Federal University of Lavras, Lavras, MG, Brazil. Electronic address:

Hydrothermally-altered feldspar (HydroPotash, HYP) possesses, among other physicochemical properties, high pH buffering and cation exchange capacity. Therefore, it may potentially remove heavy metals from aqueous solutions and immobilize these metals in contaminated soil. This study aimed to evaluate the capabilities of two types of HydroPotash (HYP-1 and HYP-2) and a zeolite sample (a commercial adsorbent) for immobilizing cadmium (Cd), zinc (Zn), and lead (Pb) from both aqueous solution and contaminated soils from a Zn-smelting area (classified as soil, soil, and soil based on their level of soluble metal concentration). Read More

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Electrostatic electron mirror in SEM for simultaneous imaging of top and bottom surfaces of a sample.

Ultramicroscopy 2021 May 3;226:113304. Epub 2021 May 3.

Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

The use of electron mirrors in aberration correction and surface-sensitive microscopy techniques such as low-energy electron microscopy has been established. However, in this work, by implementing an easy to construct, fully electrostatic electron mirror system under a sample in a conventional scanning electron microscope (SEM), we present a new imaging scheme which allows us to form scanned images of the top and bottom surfaces of the sample simultaneously. We believe that this imaging scheme could be of great value to the field of in-situ SEM which has been limited to observation of dynamic changes such as crack propagation and other surface phenomena on one side of samples at a time. Read More

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Adult child socio-economic status disadvantage and cognitive decline among older parents in Mexico.

Soc Sci Med 2021 Apr 24;279:113910. Epub 2021 Apr 24.

Leonard Davis School of Gerontology, University of Southern California, USA.

There is growing interest in the contribution of offspring educational attainment to parents' health outcomes. However, less is known about the impacts of offspring socio-economic status (SES) on parents' cognitive decline or about the role of offspring SES disadvantage. We used data from the Mexican Health and Aging Study (n = 10,426) to evaluate the impact of adult child SES disadvantage on parents' verbal memory trajectories over fourteen years (2001-2015). Read More

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Circulating Epstein-Barr virus DNA level post induction chemotherapy contributes to prognostication in advanced-stage nasopharyngeal carcinoma.

Eur J Cancer 2021 May 5;151:63-71. Epub 2021 May 5.

Department of Radiation Oncology, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-Sen University Cancer Center, No. 651 Dongfeng Eastern Road, Guangzhou, 510060, China. Electronic address:

Background: To investigate the value of post-induction chemotherapy (IC) cell-free Epstein-Barr virus DNA (cfEBV DNA) for prognostication in locally advanced nasopharyngeal carcinoma (LA-NPC).

Methods: A total of 910 histologically proven LA-NPC undergoing radical IC + concurrent chemo-radiotherapy (CCRT) or targeted radiotherapy (CTRT) or both (CTCRT) were involved. The concentration of cfEBV DNA was measured by quantitative polymerase chain reaction pre-IC (cfEBV DNA) and at IC completion. Read More

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Alpelisib in combination with everolimus ± exemestane in solid tumours: Phase Ib randomised, open-label, multicentre study.

Eur J Cancer 2021 May 5;151:49-62. Epub 2021 May 5.

Institut Gustave Roussy, Villejuif, France.

Background And Purpose: Combined mTORC1 inhibition with everolimus (EVE) and phosphatidylinositol 3-kinase catalytic subunit p110α blockade with alpelisib (ALP) has demonstrated synergistic efficacy in preclinical models and supports testing the combination of ALP and EVE in the clinical setting. The primary objective was to determine the maximum tolerated dose (MTD)/recommended dose for expansion (RDE) of ALP in combination with EVE and in combination with EVE and exemestane (EXE) and subsequently assess safety, preliminary efficacy and effect of ALP on the pharmacokinetics of EVE and determine the magnitude of the drug-drug interaction.

Patients And Methods: Dose escalation phases were conducted in patients with advanced solid tumours and in postmenopausal women with hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) advanced breast cancer (ABC). Read More

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Distribution of cyclic volatile methylsiloxanes in drinking water, tap water, surface water, and wastewater in Hanoi, Vietnam.

Environ Pollut 2021 Apr 29;285:117260. Epub 2021 Apr 29.

Faculty of Chemistry, University of Science, Vietnam National University, Hanoi, 19 Le Thanh Tong, Hanoi, 10000, Viet Nam. Electronic address:

In this study, four cyclic volatile methylsiloxanes (cVMSs) were determined in drinking water, tap water, surface water, and wastewater samples collected from Hanoi metropolitan area, Vietnam, during August to December 2020 (dry season) by using solid phase extraction combined with gas chromatography tandem mass spectrometry. Highest concentrations of cVMSs in the range of 63-7400 ng/L (mean/median: 1840/1310 ng/L) were found in wastewater samples. A significant difference existed in the concentrations of cVMSs between influent and effluent of a wastewater treatment plant. Read More

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A survey of child neurologists about reproductive healthcare for adolescent women with epilepsy.

Epilepsy Behav 2021 May 5;120:108001. Epub 2021 May 5.

UPMC Children's Hospital of Pittsburgh, Division of Adolescent and Young Adult Medicine, 4401 Penn Avenue, Pittsburgh, PA 15224, United States; Center for Women's Health Research and Innovation, University of Pittsburgh, 4200 Fifth Avenue, Pittsburgh, PA 15260, United States.

Objective: To evaluate child neurologists' knowledge, attitudes, and practices regarding sexual and reproductive health (SRH) care for adolescent and young adult women with epilepsy (WWE).

Methods: Child neurologists (including attending physicians, residents, fellows, and advanced practitioners) completed an online survey distributed through subspecialty listservs. We analyzed results using descriptive statistics, chi-square, and logistic regression. Read More

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Mal-union of sustentaculum tali fracture with talo-calcaneal coalition leading to tarsal tunnel syndrome: A case report.

Foot (Edinb) 2021 Apr 8;47:101797. Epub 2021 Apr 8.

Northwestern Memorial Hospital, Chicago, IL, USA.

Displaced isolated fractures of sustentaculum tali are rare. Inadequate treatment of these injuries can rarely lead to non-union or mal-union and in most cases are treated non-surgically. We report a unique case of undiagnosed mal-union of sustentaculum tali in the setting of underlying tarsal coalition that resulted in symptoms of tarsal tunnel. Read More

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Synthesis of bio-inspired cellulose nanocrystals-soy protein isolate nanoconjugate for stabilization of oil-in-water Pickering emulsions.

Carbohydr Res 2021 May 1;504:108336. Epub 2021 May 1.

Chemical Engineering Discipline, School of Engineering, Monash University Malaysia, Jalan Lagoon Selatan, Bandar Sunway, 47500 Subang Jaya, Selangor, Malaysia; Advanced Engineering Platform, Monash University Malaysia, Jalan Lagoon Selatan, Bandar Sunway, 47500, Subang Jaya, Selangor, Malaysia; Tropical Medicine and Biology Platform, School of Science, Monash University Malaysia, Jalan Lagoon Selatan, Bandar Sunway, 47500, Subang Jaya, Selangor, Malaysia. Electronic address:

The development of hybrid polysaccharide-protein complexes as Pickering emulsion stabilizers has attracted increasing research interest in recent years. This work presents an eco-friendly surface modification strategy to functionalize hydrophilic cellulose nanocrystals (CNC) using hydrophobic soy protein isolate (SPI) via mussel adhesive-inspired poly (l-dopa) (PLD) to develop improved nanoconjugates as stabilizers for oil-in-water Pickering emulsion. The physicochemical properties of the CNC-PLD-SPI nanoconjugate were evaluated by solid-state C NMR, FT-IR, TGA, XRD, contact angle analysis, and TEM. Read More

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Secretion of signal peptides via extracellular vesicles.

Biochem Biophys Res Commun 2021 May 5;560:21-26. Epub 2021 May 5.

Department of Brain Function, Division of Stress Adaptation and Protection, Research Institute of Environmental Medicine, Nagoya University, Nagoya, Aichi, 464-8601, Japan; Department of Molecular Pharmacokinetics, Nagoya University Graduate School of Medicine, Nagoya, Aichi, 464-8601, Japan.

Signal peptides (SPs) consist of short peptide sequences present at the N-terminal of newly synthesizing proteins and act as a zip code for the translocation of the proteins to the endoplasmic reticulum (ER). It was thought that the SPs are intracellularly degraded after translocation to the ER; however, recent studies showed cleaved SPs have diverse roles for controlling cell functions in auto- and/or intercellular manners. In addition, it still remains obscure how SP fragments translocate away from the site where they are produced. Read More

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Engineering Pseudomonas putida for efficient aromatic conversion to bioproduct using high throughput screening in a bioreactor.

Metab Eng 2021 May 5. Epub 2021 May 5.

Joint BioEnergy Institute, Lawrence Berkeley National Laboratory, 5885, Hollis Street, Emeryville, CA, USA; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Rd, Berkeley, CA, USA; Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Rd, Berkeley, CA, USA. Electronic address:

Pseudomonas putida KT2440 is an emerging biomanufacturing host amenable for use with renewable carbon streams including aromatics such as para-coumarate. We used a pooled transposon library disrupting nearly all (4,778) non-essential genes to characterize this microbe under common stirred-tank bioreactor parameters with quantitative fitness assays. Assessing differential fitness values by monitoring changes in mutant strain abundance identified 33 gene mutants with improved fitness across multiple stir-tank bioreactor formats. Read More

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Delayed egress of CD8 T cells contributes to long-term pathology after ischemic stroke in male mice.

Brain Behav Immun 2021 May 5. Epub 2021 May 5.

Department of Neurology & Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, Texas, United States; Department of Neurology, Center for Advanced Translational Stroke Science, University of Kentucky, Lexington, Kentucky, USA. Electronic address:

Objective: Stroke is a debilitating disorder with significant annual mortality and morbidity rates worldwide. Immune cells are recruited to the injured brain within hours after stroke onset and can exhibit either protective or detrimental effects on recovery. However, immune cells, including CD8 T cells, persist in the injured brain for weeks, suggesting a longer-term role for the adaptive immune system during functional recovery. Read More

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Can Adhesive Capsulitis of the shoulder be a consequence of COVID-19? Case series of 12 patients.

J Shoulder Elbow Surg 2021 May 5. Epub 2021 May 5.

Sant'Andrea Hospital - Department of Medicine and Surgery of Sapienza University of Rome, Italy.

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A basic helix-loop-helix transcription factor CabHLH113 positively regulate pepper immunity against Ralstonia solanacearum.

Microb Pathog 2021 May 5:104909. Epub 2021 May 5.

Innovative Institute for Plant Health, Zhongkai University of Agriculture and Engineering, Guangzhou, 510225, People's Republic of China; College of Agriculture and Biology, Zhongkai University of Agriculture and Engineering, Guangzhou, 510225, People's Republic of China. Electronic address:

Pepper's (Capsicum annum) response to bacterial pathogen Ralstonia solanacearm inoculation (RSI) and abiotic stresses is known to be synchronized by transcriptional network; however, related molecular mechanisms need extensive experimentation. We identified and characterized functions of CabHLH113 -a basic helix-loop-helix transcription factor-in pepper immunity to R. solanacearum infection. Read More

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Immunotherapy as Single Treatment for Non-small-cell Lung Cancer Patients with Brain Metastases: a systematic review and meta-analysis - the META-L-BRAIN study.

J Thorac Oncol 2021 May 5. Epub 2021 May 5.

AC Camargo Cancer Center, São Paulo, Brazil.

Introduction: Brain metastases (BM) occur in 40% of lung cancer patients. The activity of immunotherapy in these patients, however, remains controversial, as the cornerstone treatment is radiotherapy (RT). Since RT is associated with adverse events that may impair quality of life, the possibility of substituting it by a single systemic approach is attractive. Read More

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Comparison of clinical efficacy of neoadjuvant chemoradiotherapy between lower and higher radiation dose for carcinoma of the esophagus and gastroesophageal junction: a systematic review.

Int J Radiat Oncol Biol Phys 2021 May 5. Epub 2021 May 5.

Department of Radio-Chemotherapy, Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou City, Jiangsu Province, China. Electronic address:

Background: Neoadjuvant concurrent chemoradiotherapy (nCRT) plus surgery has been a standard treatment for locoregionally advanced esophageal cancer and carcinoma of the gastroesophageal junction (EC/GEJ), but an optimal preoperative radiation dose is still unclear.

Purpose: We performed this systematic review to explore the treatment efficacy and toxicity of different radiation dose levels and find an optimal dose-fractionation strategy in EC/GEJ patients receiving nCRT.

Methods: Embase and Ovid Medline were searched for articles involving operable squamous and adenocarcinoma of the esophagus and GEJ receiving nCRT up to a dose of 50. Read More

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MYPT1, regulated by miR-19b-3p inhibits the progression of non-small cell lung cancer via inhibiting the activation of wnt/β-catenin signaling.

Life Sci 2021 May 5:119573. Epub 2021 May 5.

Department of Respiration, The First Hospital of Jilin University, Changchun 130021, China. Electronic address:

Aims: Myosin phosphatase targeting protein 1 (MYPT1) was identified to function as a tumor suppressor in several kinds of cancers, but its role and the molecular mechanisms in non-small cell lung cancer (NSCLC) remain undiscovered. Herein, we aimed to reveal MYPT1 expression pattern and role in NSCLC, and investigate the underlying mechanisms.

Main Methods: Sixty-eight paired NSCLC tissues and the adjacent normal tissues were included in this study. Read More

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Biased re-orientation in the chemotaxis of peritrichous bacteria Salmonella enterica serovar Typhimurium.

Biophys J 2021 May 5. Epub 2021 May 5.

Department of Mechanical and Aerospace Engineering, Graduate School of Engineering, Tottori University, Tottori, Tottori 680-8552, Japan; Advanced Mechanical and Electronic System Research Center, Faculty of Engineering, Tottori University, Tottori, Tottori 680-8552, Japan.

Many kinds of peritrichous bacteria that repeat runs and tumbles by using multiple flagella exhibit chemotaxis by sensing a difference in the concentration of the attractant or repellent between two adjacent time points. If a cell senses that the concentration of an attractant has increased, their flagellar motors decrease the switching frequency from counterclockwise to clockwise direction of rotation, which causes a longer run in swimming up the concentration gradient than swimming down. We investigated the turn angle in tumbles of peritrichous bacteria swimming across the concentration gradient of a chemoattractant because the change in the switching frequency in the rotational direction may affect the way tumbles. Read More

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Structural determination of the sheath-forming polysaccharide of Sphaerotilus montanus using thiopeptidoglycan lyase which recognizes the 1,4 linkage between α-d-GalN and β-d-GlcA.

Int J Biol Macromol 2021 May 5. Epub 2021 May 5.

Faculty of Engineering, Yokohama National University, 79-5 Tokiwadai, Hodogaya, Yokohama 240-8501, Japan. Electronic address:

Sphaerotilus natans is a filamentous sheath-forming bacterium commonly found in activated sludge. Its sheath is assembled from a thiolic glycoconjugate called thiopeptidoglycan. S. Read More

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Sequence For Surgical Resection of Primary Lung Tumor For Oligometastatic Non-Small Cell Lung Cancer.

Ann Thorac Surg 2021 May 5. Epub 2021 May 5.

Division of Thoracic Oncology, Department of Chest Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.

Background: Differing surgical series for the treatment of primary lung tumor with synchronous oligometastatic stage IV non-small cell lung cancer (NSCLC) have been published; however, outcomes remain ambiguous.

Methods: Patients with synchronous oligometastatic stage IV NSCLC treated from 2005 to 2017 were enrolled to identify the impact of treatment sequence (primary lung resection versus systemic treatment) on progression-free survival (PFS) and overall survival (OS).

Results: Fifty-one patients received tumor resection (84% adenocarcinoma, 55% non-smokers, and 65% driver gene mutation). Read More

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