Adv Neurol 2006 ;99:17-21
Developmental Cognitive Neurology, Kenneldy Krieger Institute, Baltinore, Mnryland, USA.
ADHD is a complex co-morbidity, as it is heteregeneous in terms of the clinical subtypes, but also in terms of the circuits involved and the level of involvement within those circuits. Specially focusing on the relationship of ADHD to TS, this author's studies have added some neurobehavioral and some anatomical magnetic resonance imaging evidence suggesting the ADHD occurring with TS, appears like "garden-variety" ADHD, at least in the matched research sample. The similarities of neuroanatomical findings in the TS plus ADHD and ADHD groups and their distinctness from neuroanatomical findings in childdren with "pure TS provide some parallels to the observed similarity of functional deficit in TS plus ADHD and ADHD alone groups and the relative lack of functional deficits in children with TS only. Read More