57,391 results match your criteria Adrenal Surgery


The anesthetic efficiency of retromolar infiltrations with two local anesthetic solutions of the same concentration in lower third molar surgery.

J Dent Anesth Pain Med 2020 Jun 24;20(3):137-146. Epub 2020 Jun 24.

Department of Oral & Maxillofacial Surgery, Faculty of Dentistry, Mahidol University, Bangkok, Thailand.

Background: Mandibular third molar removal is the most common surgical procedure encountered in oral and maxillofacial clinics. It also presents the greatest challenges and controversies for surgeons when surgical removal is considered. Furthermore, diverse anesthesia results and success rates are achieved after using the same concentrations of different solutions or the same amounts of local anesthetics. Read More

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http://dx.doi.org/10.17245/jdapm.2020.20.3.137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321737PMC

Pheochromocytoma and Paraganglioma: From Epidemiology to Clinical Findings.

Sisli Etfal Hastan Tip Bul 2020 3;54(2):159-168. Epub 2020 Jun 3.

Department of Genaral Surgery, Health Sciences University, Sisli Hamidiye Etfal Medical Practice and Research Center, Istanbul, Turkey.

Pheochromocytomas (PCC) and paragangliomas (PGL) are rare neuroendocrine tumors. Pheochromocytomas arise from chromaffin cells in the adrenal medulla, and PGLs arise from chromaffin cells in the ganglia of the autonomic nervous system. Paragangliomas originate from sympathetic or parasympathetic ganglia in the abdomen, thorax, and pelvis. Read More

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http://dx.doi.org/10.14744/SEMB.2020.18794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326683PMC

Clinical impacts of EGFR mutation status: analysis of 5,780 surgically resected lung cancer cases.

Ann Thorac Surg 2020 Jun 29. Epub 2020 Jun 29.

Department of General Thoracic Surgery, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8677, Japan.

Background: To elucidate the clinical, pathologic, and prognostic impacts of EGFR mutation and mutation subtypes in early-stage lung cancer, we conducted a retrospective analysis of the Japanese Joint Committee of Lung Cancer Registry database (a nationwide database for surgically-resected lung cancer patients; n = 18,973).

Methods: Of 13,951 patients classified as non-squamous non-small cell lung cancer in the database, 5,780 patients (41.0%) had been tested for EGFR mutation and were included in this study. Read More

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http://dx.doi.org/10.1016/j.athoracsur.2020.05.041DOI Listing

Prevalence and risk factors associated with systemic hypertension in dogs with spontaneous hyperadrenocorticism.

J Vet Intern Med 2020 Jul 2. Epub 2020 Jul 2.

Department of Animal Medicine and Surgery, Veterinary Faculty, Complutense University of Madrid, Madrid, Spain.

Background: Systemic hypertension (SH) is common in dogs with hyperadrenocorticism (HAC) however there are not many studies assessing its prevalence and risk factors.

Objectives: To determine the prevalence and severity of SH in dogs with HAC and its association with clinical and laboratory findings to identify potential risk factors.

Animals: Sixty-six client owned dogs with spontaneous HAC. Read More

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http://dx.doi.org/10.1111/jvim.15841DOI Listing

MEN Type I (Wermer Syndrome).

J Assoc Physicians India 2020 May;68(5):51-52

PG Student, RNT Medical College, Udaipur, Rajasthan.

MEN I inherited as an autosomal dominant disorder leads to hyperplastic/ neoplastic changes in parathyroid, pituitary and endocrine pancreas along with other characteristic tumours. Hyperparathyroidism is the most common manifestation of MEN I. Our case was a female patient aged 42 years who was diagnosed with parathyroid adenoma, coincident with pancreatic neoplasm and adrenal adenoma. Read More

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Response to Letter to the Editor from Richard Dorin: Dynamic pituitary-adrenal interactions in the critically ill after cardiac surgery.

J Clin Endocrinol Metab 2020 Jul 1. Epub 2020 Jul 1.

Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology. University of Bristol. Bristol. UK.

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http://dx.doi.org/10.1210/clinem/dgaa422DOI Listing

A Novel Pathogenic Variant in the N-Terminal Domain of the Glucocorticoid Receptor, Causing Glucocorticoid Resistance.

Mol Diagn Ther 2020 Jun 30. Epub 2020 Jun 30.

Department of Basic Biotechnological Sciences, Intensivological and Perioperative Clinics, Università Cattolica del Sacro Cuore, Largo S. Vito 1, 00168, Roma, Italy.

Background: Generalized glucocorticoid resistance is characterized by impaired cortisol signaling, resulting from mutations in the NR3C1 gene coding the human glucocorticoid receptor (hGR). Most of the pathogenic hGR variants are identified in the ligand-binding domain (LBD). However, we report a new case associated with a novel NR3C1 pathogenic variant in the N-terminal domain (NTD) of the hGR. Read More

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http://dx.doi.org/10.1007/s40291-020-00480-9DOI Listing

No evidence of vertical transmission of SARS-CoV-2 after induction of labour in an immune-suppressed SARS-CoV-2-positive patient.

BMJ Case Rep 2020 Jun 30;13(6). Epub 2020 Jun 30.

Department of Obstetrics and Gynaecology, Erasmus Medical Center, Rotterdam, Zuid-Holland, The Netherlands

We present a case of a 38+1 weeks pregnant patient (G1P0) with a proven COVID-19 infection, who was planned for induction of labour because of pre-existent hypertension, systemic lupus erythematosus, respiratory problem of coughing and mild dyspnoea without fever during the COVID-19 pandemic in March 2020. To estimate the risk of vertical transmission of Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2) during labour and delivery, we collected oropharyngeal, vaginal, urinary, placental and neonatal PCRs for SARS-CoV-2 during the period of admission. All PCRs, except for the oropharyngeal, were negative and vertical transmission was not observed. Read More

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http://dx.doi.org/10.1136/bcr-2020-235581DOI Listing

Comparison of the Cost and Efficacy of Axillary Anesthesia and Wide-Awake Anesthesia in Finger Surgeries.

Sisli Etfal Hastan Tip Bul 2018 12;52(2):119-123. Epub 2018 Jun 12.

Department of Orthopedics, University of Health Sciences, Erzurum Regional Training and Research Hospital, Erzurum, Turkey.

Objectives: Wide-awake anesthesia is a type of local anesthesia consisting of a combined application of lidocaine, epinephrine, and bicarbonate and has a wide potential in hand surgery as it offers the advantage of being applied without sedation and without using a tourniquet. In light of recent studies, its use has increased with the disappearance of the belief among surgeons that epinephrine can cause circulatory disturbance in fingers.

Methods: Patients with finger pathologies who were operated upon at the Baltalimani Bone Diseases Teaching and Research Hospital between January 2015 and February 2016 were divided into two groups according to anesthesia type: wide-awake anesthesia and axillary block anesthesia, with 52 patients in each group. Read More

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http://dx.doi.org/10.14744/SEMB.2017.17363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315058PMC

Cleft Palate Repair: A New Maxillary Nerve Block Approach.

J Craniofac Surg 2020 Jun 24. Epub 2020 Jun 24.

Asociacion PIEL.

Objective: To introduce a different approach for maxillary nerve block (MNB), in cleft palate repair. To reduce the use of opioids during surgery and to prevent frequent respiratory complications by means of an adequate intra and postoperative pain relief.

Patients And Methods: A prospective clinical trial was planned, to collect scientific evidences between 2 groups of patients with primary cleft palate, receiving surgery in 2 Pediatric centers of Buenos Aires, utilizing a different protocol. Read More

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http://dx.doi.org/10.1097/SCS.0000000000006633DOI Listing

Onset, Duration, and Pain Score Obtained Using Lidocaine Mixed With Epinephrine and Bicarbonate in Plastic Surgery.

Authors:
Hun Kim Kun Hwang

J Craniofac Surg 2020 Jun 24. Epub 2020 Jun 24.

Department of Plastic Surgery, Inha University School of Medicine, Incheon, Korea.

The aim of this study was to systematically review the effects of lidocaine mixed with epinephrine and bicarbonate in plastic surgery in terms of onset, duration, and the pain score.In PubMed, Embase, Web of Science, and the Cochrane Library, the terms "epinephrine" AND "lidocaine" AND "plastic surgery" were searched, resulting in 210 titles. Among them, 25 full papers were reviewed, 11 were excluded, and 5 mined papers were added. Read More

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http://dx.doi.org/10.1097/SCS.0000000000006627DOI Listing

Safety and Efficacy of Budesonide for Liver Transplant Immune Suppression: Results of a Pilot Phase 2a trial.

Liver Transpl 2020 Jun 30. Epub 2020 Jun 30.

University of Cincinnati, Division of Digestive Diseases, Department of Medicine, Cincinnati, Ohio, USA.

Background And Aims: Despite adverse effects like hyperglycemia, New Onset Diabetes After Transplant (NODAT) and infectious complications; corticosteroids remains an important part of liver transplant (LT) immune suppression. Budesonide, a synthetic corticosteroid, undergoes extensive first-pass hepatic metabolism with only 10% systemic bioavailability, providing an opportunity for improved toxicity-therapeutic ratio. Although effective in the treatment of autoimmune hepatitis, effects of budesonide for LT immune suppression are unknown. Read More

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http://dx.doi.org/10.1002/lt.25837DOI Listing

Survivorship in immune therapy: Assessing toxicities, body composition and health-related quality of life among long-term survivors treated with antibodies to programmed death-1 receptor and its ligand.

Eur J Cancer 2020 Jun 26;135:211-220. Epub 2020 Jun 26.

Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.

Aim: Antibodies to programmed death-1 receptor and its ligand (anti-PD-1/PD-L1) produce durable responses in many cancers. However, the long-term effects of anti-PD-1/PD-L1 blockade are not well defined. We identified the toxicities, health outcomes and health-related quality of life (HRQoL) amongst long-term survivors treated with anti-PD-1/PD-L1. Read More

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http://dx.doi.org/10.1016/j.ejca.2020.05.005DOI Listing

[Primary hyperaldosteronism: difficulties in diagnosis].

Ter Arkh 2019 Oct 15;91(10):91-99. Epub 2019 Oct 15.

Endocrinology Research Centre.

Primary hyperaldosteronism (PA) - is the clinical syndrome, results from autonomous of the major regulators of secretion, aldosterone overproduction by a tumorous or hyperplastic tissue in adrenal cortex. Being the most frequent cause of secondary hypertension, PA may be represented by disorders with unilateral or bilateral aldosterone overproduction and differential diagnosis between them is crucial for choosing a right therapeutic approache: lifelong medical therapy with mineralocorticoid receptor antagonists or unilateral adrenalectomy. Adrenal venous sampling (AVS) is currently the «gold standard» test for identifying laterality of excess hormone production, unlike imaging tests, sensitivity and specificity of which is not enough, due to inability to evaluate functional activity with confidence, and also to limitations in detecting tiny abnormalities of adrenals, such as microadenoma or hyperplasia. Read More

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http://dx.doi.org/10.26442/00403660.2019.10.000138DOI Listing
October 2019

Letter to the Editor from Richard Dorin: "Dynamic pituitary-adrenal interactions in the critically ill after cardiac surgery".

J Clin Endocrinol Metab 2020 Jun 29. Epub 2020 Jun 29.

Professor of Statistics and Mathematics Emeritus, University of New Mexico.

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http://dx.doi.org/10.1210/clinem/dgaa418DOI Listing

Spontaneous intra-adrenal massive hematoma: possible extreme evolution of a non-secreting untreated adrenal adenoma.

J Surg Case Rep 2020 Jun 19;2020(6):rjaa185. Epub 2020 Jun 19.

Urological Clinic, Department of Surgical, Oncological and Gastroenterological Sciences, University of Padua, 35121 Padua, Italy.

The spontaneous adrenal hematoma is a rare event. An 83-year-old male patient presented a 26-cm asymptomatic retroperitoneal mass of doubtful renal-adrenal origin. He had been evaluated 10 years before for an adrenal incidentaloma of 2. Read More

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http://dx.doi.org/10.1093/jscr/rjaa185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303019PMC

Rare case of pseudohypoaldosteronism in a neonate secondary to congenital hydrometrocolpos.

BMJ Case Rep 2020 Jun 28;13(6). Epub 2020 Jun 28.

Department of Paediatrics and Neonatology, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UK.

Pseudohypoaldosteronism (PHA) due to obstructive uropathy, urinary tract infections and congenital urogenital malformations has been reported in the literature; however, there are no reports of PHA associated with hydrometrocolpos due to a common urogenital tract. Hydrometrocolpos is a condition resulting in distension of the vagina and uterus due to accumulation of secretions (other than blood), caused by increased oestrogenic stimulation and vaginal outflow obstruction. We report on a neonatal case of PHA caused by recurrent hydrometrocolpos presenting with vomiting and poor weight gain. Read More

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http://dx.doi.org/10.1136/bcr-2020-234813DOI Listing

Severe low cerebral oximetry in difficult cardiopulmonary bypass weaning of low body-weight infant: a case report and literature review.

Authors:
Xuechao Hao Wei Wei

BMC Anesthesiol 2020 Jun 27;20(1):159. Epub 2020 Jun 27.

Department of Anesthesiology, The Research Unit of Perioperative Stress Assessment and Clinical Decision (2018RU012), Chinese Academy of Medical Sciences, West China Hospital, Sichuan University, 610041, Chengdu, People's Republic of China.

Background: For infants undergoing complex cardiac surgery, hemodynamic management after cardiopulmonary bypass (CPB) is challenging because of severe myocardial edema, vasomotor dysfunction and weak tolerance to a change in blood volume. More importantly, the lack of availability of equipment for advanced monitoring, such as transesophageal echocardiography or transthoracic echocardiography, restricts the accurate assessment of hemodynamics.

Case Presentation: This is a case of severe hypotension and non-detectable pulse oxygen saturation (SpO) after CPB in a low-weight infant who had normal blood pressure and oxygen saturation before surgery. Read More

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http://dx.doi.org/10.1186/s12871-020-01071-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320539PMC

Acute haemoperitoneum caused by ruptured extra-adrenal paraganglioma.

ANZ J Surg 2020 Jun 27. Epub 2020 Jun 27.

Department of Hospital Pathology, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

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http://dx.doi.org/10.1111/ans.16088DOI Listing

Unusual local and distant metastases after complete resection of roentgenographically occult squamous cell carcinoma.

Gen Thorac Cardiovasc Surg 2020 Jun 26. Epub 2020 Jun 26.

Department of Thoracic Surgery, Kanazawa Medical University, 1-1 Daigaku, Uchinada, Ishikawa, 920-0293, Japan.

Roentgenographically occult squamous cell carcinoma (ROSCC) was reported to have been cured after complete resection. We experienced unusual local and distant metastases after complete resection of a ROSCC of left B6 bronchus. During the operation due to the proximal bronchial stump being positive for squamous cell carcinoma (SCC), a left lower sleeve lobectomy was performed. Read More

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http://dx.doi.org/10.1007/s11748-020-01420-4DOI Listing

Superior Effects of Nebulized Epinephrine to Nebulized Albuterol and Phenylephrine in Burn and Smoke Inhalation-Induced Acute Lung Injury.

Shock 2020 Jun 23. Epub 2020 Jun 23.

Department of Anesthesiology, The University of Texas Medical Branch, Galveston, TX, USA.

The severity of burn and smoke inhalation-induced acute lung injury (BSI-ALI) is associated with alveolar and interstitial edema, bronchospasm, and airway mucosal hyperemia. Previously we have reported beneficial effects of epinephrine nebulization on BSI-ALI. However, the underlying mechanisms of salutary effects of nebulized epinephrine remain unclear. Read More

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http://dx.doi.org/10.1097/SHK.0000000000001590DOI Listing

Ongoing 5-year+ survival after multiple metastasectomies, followed by CAPOX plus bevacizumab, for metastatic colorectal cancer.

Surg Case Rep 2020 Jun 26;6(1):149. Epub 2020 Jun 26.

Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556, Japan.

Background: Advancements in chemotherapy for metastatic colorectal cancer (mCRC) have improved long-term outcomes, and median survival currently exceeds 30 months. The recommended treatment for mCRC is multidisciplinary, including a combination of surgical resection and chemotherapy. In this study, we report the case of a patient who has survived for more than 5 years after an initial diagnosis of mCRC while undergoing first-line chemotherapy and six repeat metastasectomies. Read More

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http://dx.doi.org/10.1186/s40792-020-00913-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316900PMC

Recurrent Amplification of the Osmotic Stress Transcription Factor in Adrenocortical Carcinoma.

J Endocr Soc 2020 Jul 25;4(7):bvaa060. Epub 2020 May 25.

Department of Surgery & Yale Endocrine Neoplasia Laboratory, Yale University School of Medicine, New Haven, Connecticut.

Tumorigenesis requires mitigation of osmotic stress and the transcription factor nuclear factor of activated T cells 5 (NFAT5) coordinates this response by inducing transcellular transport of ions and osmolytes. NFAT5 modulates in vitro behavior in several cancer types, but a potential role of NFAT5 in adrenocortical carcinoma (ACC) has not been studied. A discovery cohort of 28 ACCs was selected for analysis. Read More

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http://dx.doi.org/10.1210/jendso/bvaa060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304660PMC

Avascular necrosis of the femoral head due to low-dose corticosteroid used in a patient with panhypopituitarism: A case report and literature review.

Jt Dis Relat Surg 2020 18;31(2):390-394. Epub 2020 Jun 18.

Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi, Endokrinoloji ve Metabolizma Kliniği, 06110 Dışkapı, Ankara, Türkiye.

Osteonecrosis, commonly known as avascular necrosis (AVN) of bone, is one of the universally recognized side effects of high-dose steroids and commonly involves femur head leading to significant morbidity. However, the development of AVN in the femoral head due to low-dose oral corticosteroid therapy in a short time is a rare occurrence. Management by stopping corticosteroid treatment can be challenging in many cases due to the adrenal crisis. Read More

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http://dx.doi.org/10.5606/ehc.2020.72773DOI Listing

EUS-B-FNA for Left Adrenal Lesions in Non-Small Cell Lung Cancer Patients: Report of Cases and Literature Review.

Turk Thorac J 2020 May;21(3):209-212

Department of Pathology, Dr. Suat Seren Training and Research Hospital for Pulmonary Diseases and Thoracic Surgery, İzmir, Turkey.

The left adrenal gland (LAG) is a common metastatic site in patients with non-small-cell lung cancer. In practice, staging mainly relies on radiologic studies and endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA). Recently, a new technique using convex probe-endobronchial ultrasound (CP-EBUS) scope through the esophagus (EUS-B) has been introduced. Read More

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http://dx.doi.org/10.5152/TurkThoracJ.2019.190109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311151PMC

Short-term outcome of adrenalectomy in dogs with adrenal gland tumours that did not receive pre-operative medical management.

Aust Vet J 2020 Jun 24. Epub 2020 Jun 24.

School of Veterinary Medicine, Murdoch University, Perth, Australia.

Objective: Review medical records of dogs that underwent adrenalectomy without pre-operative medical management, to examine the peri-operative morbidity and mortality.

Design: Case series of 65 dogs.

Methods: Medical records were reviewed. Read More

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http://dx.doi.org/10.1111/avj.12991DOI Listing

Influence of Preemptive Analgesia with Oxycodone Hydrochloride on Stress Hormone Level of Geriatric Patients undergoing Gastrointestinal Surgery.

J Coll Physicians Surg Pak 2020 May;30(5):476-479

Department of Scientific Research, Affiliated Hospital of Hebei University, Baoding, Hebei, P. R. China.

Objective: To determine the influence of preemptive analgesia with oxycodone hydrochloride on stress hormone level of geriatric patients undergoing gastrointestinal surgery, and evaluate the analgesic effect.

Study Design: Rrandomised controlled trial.

Place And Duration Of Study: Department of Anaesthesiology, Baoding First Central Hospital, from January to December 2017. Read More

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http://dx.doi.org/10.29271/jcpsp.2020.05.476DOI Listing

Wide-field polygon-scanning photoacoustic microscopy of oxygen saturation at 1-MHz A-line rate.

Photoacoustics 2020 Dec 7;20:100195. Epub 2020 Jun 7.

Department of Biomedical Engineering, City University of Hong Kong, 83 Tat Chee Ave, Kowloon, Hong Kong SAR, China.

We report wide-field polygon-scanning functional OR-PAM that for the first time achieves 1-MHz A-line rate of oxygen saturation in vivo. We address two technical challenges. The first is a 1-MHz dual-wavelength pulsed laser that has sufficient pulse energy and ultrafast wavelength switching. Read More

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http://dx.doi.org/10.1016/j.pacs.2020.100195DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300162PMC
December 2020

Favorable outcomes of surgical resection for extrahepatic recurrent hepatocellular carcinoma.

Hepatol Res 2020 Jun 23. Epub 2020 Jun 23.

Department of Digestive Surgery, Nihon University School of Medicine, Tokyo, Japan.

Aim: Repeat resection for intrahepatic recurrent hepatocellular carcinoma (HCC) is effective for the long-term survival of patients; however, little is known about the surgical outcomes of extrahepatic nodules. The aim of this study is to investigate whether resection can contribute to the survival of patients with extrahepatic recurrent HCC.

Methods: Under the conditions that intrahepatic recurrent HCC was absent or controlled by locoregional therapies, patients who had resectable extrahepatic recurrent HCC in the lymph nodes, adrenal gland, peritoneum, lung, or brain were included in this study. Read More

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http://dx.doi.org/10.1111/hepr.13526DOI Listing

Adrenocortical tumors in children.

Semin Pediatr Surg 2020 Jun 17;29(3):150927. Epub 2020 May 17.

Division of Pediatric Surgery, Department of Surgery, University of Utah School of Medicine, 100N Mario Cappecchi Dr., Suite #3800, Salt Lake City, UT, United States.

Adrenocortical neoplasms are rare in childhood. Unlike their adult counterparts, they are often hormonally active and malignant. Despite being uncommon, adrenocortical neoplasms in children have significant associated morbidity and require complete surgical resection for effective management. Read More

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http://dx.doi.org/10.1016/j.sempedsurg.2020.150927DOI Listing

A case report of rare ectopic pheochromocytoma adjacent to pancreas.

Medicine (Baltimore) 2020 Jun;99(25):e20858

Department of General Surgery, Wuxi People's Hospital Affiliated Nanjing Medical University, Jiangsu Wuxi, China.

Rationale: Ectopic pheochromocytoma is a special type of pheochromocytoma which occurs outside the adrenal gland. The most common symptoms of ectopic pheochromocytoma are palpitations, headaches, profuse sweating, and hypertension. In clinical practice, diagnosis of ectopic pheochromocytoma remains difficult. Read More

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http://dx.doi.org/10.1097/MD.0000000000020858DOI Listing

Intraoperative Management of Large Resuscitation-Associated Venous Air Embolism (VAE) for Emergent Neurological Surgery.

Case Rep Anesthesiol 2020 6;2020:8868037. Epub 2020 Jun 6.

Mayo Clinic, Department of Anesthesiology and Perioperative Medicine, Rochester, MN, USA.

Venous air embolism (VAE) is a well-described phenomenon that may have life-threatening cardiopulmonary and neurological consequences. Accidental administration of air during resuscitation while using a rapid infuser is rare. Furthermore, there is a paucity of published data describing the intraoperative management of VAE during emergent nonseated neurological surgery. Read More

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http://dx.doi.org/10.1155/2020/8868037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294353PMC

Effect of Fungus on the Hypothalamic-Pituitary-Adrenal Axis in Lewis Rats with Kidney-Yang Deficiency Syndrome.

Evid Based Complement Alternat Med 2020 19;2020:5952612. Epub 2020 May 19.

The Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou 310053, China.

Kidney-yang deficiency syndrome (KYDS) is a classic syndrome in traditional Chinese medicine, which is mainly caused by damage to the hypothalamic-pituitary-adrenal (HPA) axis. sinensis fungus (HSF), an artificial substitute of has been widely used in TCM. However, the effects and the possible mechanism of HSF on the HPA axis and corresponding KYDS have not yet been investigated. Read More

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http://dx.doi.org/10.1155/2020/5952612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256706PMC

Development and validation of prediction models for subtype diagnosis of patients with primary aldosteronism.

J Clin Endocrinol Metab 2020 Jun 19. Epub 2020 Jun 19.

Division of Internal Medicine and Hypertension, Department of Medical Sciences, University of Torino, Italy.

Context: Primary aldosteronism (PA) comprises unilateral (lateralized, LPA) and bilateral disease (BPA). The identification of LPA is important to recommend potentially curative adrenalectomy. Adrenal venous sampling (AVS) is considered the gold standard for PA subtyping, but the procedure is available in few referral centers. Read More

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http://dx.doi.org/10.1210/clinem/dgaa379DOI Listing

Adrenal crises in older patients.

Lancet Diabetes Endocrinol 2020 Jul;8(7):628-639

Department of Endocrinology, Metabolism and Diabetes, Karolinska University Hospital, Stockholm, Sweden; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden. Electronic address:

Adrenal crises are severe manifestations of adrenal insufficiency that result in hospital admission and incur a risk of cardiovascular events, acute renal injury, and death. Evidence from population-based studies indicate that adults older than 60 years have the highest adrenal insufficiency incidence, contribute to the highest number of adrenal crises, and have the highest age-specific incidence of adrenal crisis, which doubles between the age groups of 60-69 years and 80 years or older. Older patients might be more susceptible to adrenal crises because of a higher prevalence of comorbidities and a consequently higher risk of acute illness. Read More

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http://dx.doi.org/10.1016/S2213-8587(20)30122-4DOI Listing

Combining Appleby with RAMPS - Laparoscopic Radical Antegrade Modular Pancreatosplenectomy with Celiac Trunk Resection.

J Gastrointest Surg 2020 Jun 17. Epub 2020 Jun 17.

Department of Surgery, St Elizabeth's Medical Center, Tufts University School of Medicine, 11 Nevins St., Suite 201, Boston, MA, 02135, USA.

Background: Radical Antegrade Modular Pancreatosplenectomy (RAMPS) minimizes the risk of a positive retroperitoneal margin and maximizes lymph node harvest in distal pancreatic cancers.1-7 In those with celiac trunk involvement, resection of the celiac trunk (modified Appleby procedure) is a surgical option in which postoperative liver perfusion relies on blood flow via superior mesenteric artery (SMA) and gastroduodenal artery (GDA).8, 9 PATIENT: A 66-year-old male was diagnosed with a 3. Read More

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http://dx.doi.org/10.1007/s11605-020-04686-4DOI Listing

Effect of cocktail therapy after arthroscopic rotator cuff repair: a randomized, double-blind trial.

Authors:
Takeshi Teratani

J Shoulder Elbow Surg 2020 Jul;29(7):1310-1315

Ouryouji Orthopaedic Hospital, Kobayashi, Japan. Electronic address:

Background: We investigated the effectiveness of cocktail therapy after arthroscopic rotator cuff repair (ARCR).

Methods: We evaluated 128 shoulders undergoing ARCR and used block randomization to divide patients into 2 groups in this double-blind trial: The cocktail group received 20 mL of 0.75% ropivacaine, 5 mg of morphine, 0. Read More

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http://dx.doi.org/10.1016/j.jse.2020.03.004DOI Listing

Primary pulmonary paraganglioma: Two cases.

Turk Gogus Kalp Damar Cerrahisi Derg 2019 Jun 22;28(2):394-398. Epub 2020 Apr 22.

Department of Thoracic Surgery, Ankara University School of Medicine, Ankara, Turkey.

Paraganglioma is a rare tumor originating from extra-adrenal chromaffin cells. Primary pulmonary paraganglioma can also be seen in pediatric patients. Due to its endobronchial localization, morphological features, and neuroendocrine immunohistochemical profile, primary pulmonary paraganglioma can be confused with carcinoid tumor. Read More

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http://dx.doi.org/10.5606/tgkdc.dergisi.2020.18844DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298379PMC

Nail Surgery Myths and Truths.

J Drugs Dermatol 2020 Mar;19(3):230-234

Introduction: There is a paucity of randomized trials on nail surgery. Since there are no established guidelines, dermatologists may have false beliefs about best practices in performing nail surgery and post-procedural care.

Methods: We identified five common myths concerning nail surgery. Read More

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Pleomorphic Leiomyosarcoma of the Adrenal Gland in a Young Woman: A Case Report and Review of the Literature.

Onco Targets Ther 2020 26;13:4705-4713. Epub 2020 May 26.

Department of Anesthesiology, The First Hospital of Jilin University, Changchun, Jilin, People's Republic of China.

Leiomyosarcoma usually arises in the uterus, abdominal and urologic viscera, and walls of large and small blood vessels. However, primary adrenal leiomyosarcoma is extremely rare with only 39 cases previously reported in English-language literature. We report a case of a 29-year-old previously healthy woman with an incidentally found right adrenal-occupying lesion. Read More

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http://dx.doi.org/10.2147/OTT.S254162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263850PMC

Differential diagnosis and laparoscopic resection of an adrenal pseudocyst: A case report.

Int J Surg Case Rep 2020 Jun 9;72:178-182. Epub 2020 Jun 9.

Department of Surgery, Kanto Rosai Hospital, 1-1 Kizukisumiyoshicho, Nakahara-ku, Kanagawa, 211-8510, Japan. Electronic address:

Background: Adrenal pseudocysts are infrequent entities and definite preoperative diagnosis is difficult. We present a case of left adrenal pseudocyst, which was intraoperatively identified as having an adrenal origin and was resected using a laparoscopic approach.

Presentation Of Case: A 41-year-old female was referred to our hospital for examination and treatment of a cystic lesion in the pancreatic tail. Read More

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http://dx.doi.org/10.1016/j.ijscr.2020.05.082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298542PMC

[Diagnosis and Treatment of Primary Aldosteronism in West China Hospital of Sichuan University from 2009 to 2018].

Sichuan Da Xue Xue Bao Yi Xue Ban 2020 May;51(3):292-297

Adrenal Center, Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu 610041, China.

Objective: To summary the clinical diagnosis and treatment of primary aldosteronism (PA) in West China Hospital (WCH) of Sichuan University during 2009-2018.

Methods: This study enrolled the patients diagnosed as PA and admitted in WCH of Sichuan University from January 2009 to December 2018. The information of the patients including epidemiological and clinical data, diagnosis and treatment as well as therapeutic outcomes were collected and analyzed. Read More

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http://dx.doi.org/10.12182/20200360108DOI Listing

A Modern Assessment of Cancer Risk in Adrenal Incidentalomas: Analysis of 2219 Patients.

Ann Surg 2020 Jun 11. Epub 2020 Jun 11.

Department of Endocrine Surgery, Cleveland Clinic, Cleveland, OH.

Objective: The aim of this study was to analyze the incidence of and risk factors for adrenocortical carcinoma (ACC) in adrenal incidentaloma (AI).

Summary Of Background Data: AI guidelines are based on data obtained with old-generation imaging and predominantly use tumor size to stratify risk for ACC. There is a need to analyze the incidence and risk factors from a contemporary series. Read More

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http://dx.doi.org/10.1097/SLA.0000000000004048DOI Listing

[A Thoracic Aortic Dissection Case during Treatment with Ramucirumab plus Nab-Paclitaxel].

Gan To Kagaku Ryoho 2020 Jun;47(6):981-983

Dept. of Surgery, Iwate Medical University.

Ramucirumab(RAM)plus nab-paclitaxel(nab-PTX)therapy is a regimen that is recommended for the second round of chemotherapy in recurrent, progressive gastric cancer. We report the first case of a thoracic aortic dissection developed during RAM plus nab-PTX therapy. A 59-year-old male who had undergone a proximal gastrectomy for esophagogastric junction cancer had a recurrence of cancer 6 years later(metastasis to the para-aortic lymph node and left adrenal gland, local recurrence, and multiple bone metastases). Read More

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Two subsequent metachroneus solid tumors: Oncocytic variant adrenocortical carcinoma and rhabdomyosarcoma of childhood: Case report and Literature Review.

J Clin Res Pediatr Endocrinol 2020 Jun 16. Epub 2020 Jun 16.

Pediatrics, University of Health Sciences, Gulhane Training and Research Hospital, Ankara, Turkey.

Most cases of malignancies appear to be sporadic, but some syndromes are associated with malignancies with germline variants. Herein, a child with an unusual association of oncocytic variant adrenocortical carcinoma (ACC) and rhabdomyosarcoma was presented. An 18-month-old-boy was admitted with virilization of the genital area, penis enlargement, and erection which had begun six months ago. Read More

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http://dx.doi.org/10.4274/jcrpe.galenos.2020.2020.0060DOI Listing

Primary Adrenal Leiomyosarcoma: Clinical, Radiological, and Histopathological Characteristics.

J Endocr Soc 2020 Jun 15;4(6):bvaa055. Epub 2020 May 15.

Department of Internal Medicine and Clinical Nutrition, Institute of Medicine at Sahlgrenska Academy, University of Gothenburg and The Department of Endocrinology, Sahlgrenska University Hospital, Gothenburg, Sweden.

Primary adrenal leiomyosarcoma (PAL) is a rare, high-grade proliferating mesenchymal tumor with a considerable risk of metastasis, deriving from the smooth muscle wall of a central adrenal vein, or its tributaries. Roughly 40 patients with PAL have been reported in the literature. Herein, we present 3 patients with incidentally discovered PAL, along with an overview of the current knowledge on the clinical, radiological, and histopathological characteristics of PAL. Read More

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http://dx.doi.org/10.1210/jendso/bvaa055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278282PMC

Characterization of Group I Metabotropic Glutamate Receptors in Rat and Human Adrenal Glands.

Front Physiol 2020 27;11:401. Epub 2020 May 27.

Henan Key Laboratory of Neural Regeneration and Repairment, The First Affiliated Hospital of Xinxiang Medical University, Henan Neurology Institute, Weihui, China.

Glutamate and its receptors have been demonstrated to promote both basal and nicotine-evoked catecholamine release in bovine chromaffin cells. Multiple glutamate receptors, including metabotropic glutamate receptors (mGluRs), are found in the adrenal glands of several species, as well as in chromaffin cells. However, there is limited information available regarding the expression of glutamate metabotropic receptor mRNAs and the detailed localization of group I mGluRs (mGluR1 and mGluR5) in the rat and human adrenal cortex and medulla. Read More

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http://dx.doi.org/10.3389/fphys.2020.00401DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7267184PMC

Precise Mapping of Intra-Adrenal Aldosterone Activities Provides a Novel Surgical Strategy for Primary Aldosteronism.

Hypertension 2020 Jun 15:HYPERTENSIONAHA11914341. Epub 2020 Jun 15.

From the Endocrinology and Diabetes Center, Yokohama Rosai Hospital, Japan (T.K., K.K.K., M.O., T.T., Y.T., H.K., J.S., T.N.).

Segmental selective adrenal venous sampling (sAVS) elucidates an intraadrenal aldosterone activity map (IAMap), which allows us to design a novel surgical treatment strategy for patients with primary aldosteronism. We evaluated the usefulness of sAVS by analyzing 278 patients with whom we had prospectively used IAMap using the criteria of sAVS for surgical indication between 2009 and 2015. We evaluated its diagnostic accuracy using pathological and postsurgical biochemical and clinical outcomes. Read More

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.119.14341DOI Listing

Laboratory assessment of trilostane treatment in dogs with pituitary-dependent hyperadrenocorticism.

J Vet Intern Med 2020 Jun 13. Epub 2020 Jun 13.

Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, California, USA.

Background: Results of ACTH stimulation test (ACTHst), pre- and post-trilostane serum cortisol concentrations (SCCs), urine concentration (urine-specific gravity [USG]), and urine cortisol : creatinine ratios (UCCRs) are common variables used to monitor trilostane treatment of dogs with pituitary-dependent hyperadrenocorticism (PDH). However, none has consistently discriminated dogs receiving an adequate dose (A) from those overdosed (O) or underdosed (U).

Objectives: To assess and compare recommended monitoring variables, including serial SCCs in a cohort of dogs with PDH treated with trilostane. Read More

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http://dx.doi.org/10.1111/jvim.15830DOI Listing

Adrenocortical neoplasm of uncertain malignant potential with a myelolipomatous component.

BMJ Case Rep 2020 Jun 11;13(6). Epub 2020 Jun 11.

Baylor College of Medicine, Houston, Texas, USA

Macroscopic fat inside an adrenal lesion on CT is pathognomonic for myelolipoma, a benign neoplasm. Without macroscopic fat, it can be difficult to discern the nature of an indeterminate adrenal mass on imaging. One possible diagnosis for an indeterminate lesion without macroscopic fat is an adrenal oncocytic neoplasm (AON). Read More

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http://dx.doi.org/10.1136/bcr-2020-234591DOI Listing