Search Our Scientific Publications & Authors

Int J Appl Basic Med Res 2021 Jan-Mar;11(1):60-62. Epub 2021 Jan 26.

Department of Urology, Muljibhai Patel Urological Hospital, Nadiad, Gujarat, India.

Myelolipoma of the kidney is a very rare benign disease which is composed of mature adipose tissue admixed with mature hematopoietic elements in varying proportions. The most common location of myelolipoma is in the adrenal glands, but extra-adrenal myelolipomas in other locations such as the retroperitoneum, presacral region, pelvis, and mediastinum has also been reported. In this case report, we present a case of huge extra-adrenal myelolipoma in renal parenchyma which is rare site for its origin. Read More

Abdom Radiol (NY) 2021 Apr 8. Epub 2021 Apr 8.

Department of Radiology, Harvard Medical School, Massachusetts General Hospital, 55 Fruit Street, White 270, Boston, MA, 02114-2696, USA.

Purpose: To investigate the diagnostic performance of dual-layer dual-energy CT (dlDECT) in the evaluation of adrenal nodules.

Methods: In this retrospective study, 66 patients with triphasic dlDECT (unenhanced, venous phase (VP), delayed phase (DP)) for suspected adrenal lesions were included. Virtual unenhanced images (VUE) were derived from VP acquisitions. Read More

Georgian Med News 2021 Jan(310):7-11

Sakarya University, Medicine Faculty, Department of Internal Medicine; Sakarya University, Turkey.

We present a case of androgen and glucocorticoid secreting adrenocortical carcinoma with concomitant myelolipoma. A giant adrenal tumor which was initially nonfunctional was reassessed four years later due to the patient's refusal to treat. The patient was a 48-year-old woman with hypertension and acne lesions on the face. Read More

Radiol Case Rep 2021 Feb 5;16(2):364-368. Epub 2020 Dec 5.

Department of Radiology, University of Missouri Health Care, Columbia, One Hospital Dr., Columbia, MO 65212 USA.

Myelolipomas are rare benign tumors that contain a mix of fatty and hematopoietic tissues. These tumors are frequently seen in the adrenal glands. While extra-adrenal myelolipomas are extremely rare, once identified, they are commonly found in the retroperitoneum--particularly the presacral region. Read More

BMJ Case Rep 2021 Jan 29;14(1). Epub 2021 Jan 29.

Department of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, India

A 38-yearr-old man presented with erectile dysfunction and infertility. On examination, he was hypertensive and detected to have a left flank mass. Blood investigations were unremarkable except raised serum noradrenaline levels. Read More

Endocr Pract 2020 Nov;26(11):1351-1365

the Department of Endocrinology, Metabolism and Diabetes, Karolinska University Hospital, Stockholm, Sweden; the Departement of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.

Objective: The prevalence of adrenal tumors in congenital adrenal hyperplasia (CAH) is uncertain. Our objective was to estimate the prevalence and characteristics of adrenal tumors and myelolipoma in CAH, and investigate clinical features of this population.

Methods: We carried out systematic searches in Medline Ovid and Embase for articles published until January, 2020. Read More

Gland Surg 2020 Dec;9(6):2331-2342

Department of Precision Medicine, University of Campania "L. Vanvitelli", Naples, Italy.

The purpose of this pictorial essay is to review the imaging findings of adrenal lesions. Adrenal lesions could be divided into functioning or non-functioning masses, primary or metastatic, and benign or malignant. Imaging techniques have undergone significant advances in recent years. Read More

Radiol Case Rep 2021 Feb 11;16(2):396-399. Epub 2020 Dec 11.

Department of Surgical Pathology, The Warren Alpert Medical School of Brown University, Rhode Island Hospital, Providence, RI, USA.

Ganglioneuromas are rare tumors that occur spontaneously or arise from a poorly differentiated neuroblastic tumor. Although they are typically described in the pediatric population, they can occur in adults. Ganglioneuromas are often discovered incidentally and their typical imaging appearance, although non-specific, is that of a well-defined solid mass. Read More

AACE Clin Case Rep 2020 Mar-Apr;6(2):e54-e58. Epub 2020 Dec 20.

Objective: Adrenal myelolipoma (AM) is a benign tumor composed of mature fat cells and hemopoietic elements. Most AMs are incidental findings on imaging and clinically asymptomatic. The purpose of this case report is to describe a rare case of AM and explore its clinical manifestations, imaging features, and treatment. Read More

Cir Cir 2020 ;88(Suppl 2):52-55

Servicio de Cirugía General, Hospital Privado Universitario de Córdoba, Córdoba, Argentina.

El mielolipoma es un tumor benigno de baja incidencia cuya localización más frecuente son las glándulas suprarrenales. Histológicamente se caracteriza por células con precursores mieloides y eritroides mezcladas con tejido adiposo maduro. El diagnóstico en general es incidental en una prueba de imagen. Read More

Clin Nucl Med 2021 Jan;46(1):38-39

From the Departments of Nuclear Medicine.

Myelolipoma is a rare mesenchymal tumor consisting of adipose tissue and hematopoietic cells. Found usually in the adrenal region, however, few cases have been reported in extra-adrenal regions, most frequently in the presacral region. It is important to recognize such tumor, as it can attain massive size and causes pressure symptoms, and needs to be differentiated from malignant tumors, including liposarcomas. Read More

Arch Ital Urol Androl 2020 Oct 1;92(3). Epub 2020 Oct 1.

Urology, Galliera Hospital, Genoa.

Adrenal myelolipoma (AML) is a rare benign tumor, usually non-functioning and asymptomatic until it reaches large size. AML is mostly detected incidentally by imaging and is composed of adipose tissue and hematopoietic elements. Only symptomatic tumor needs surgical excision. Read More

Ann Med Surg (Lond) 2020 Sep 2;57:274-280. Epub 2020 Aug 2.

Department of Orthopedics, Leiden University Medical Center, Leiden, the Netherlands.

Introduction: Myelolipomas are very rare benign tumours consisting of hematopoietic cells and mature adipose tissues. They are most commonly found in the adrenal glands. However, there have been several reported cases of extra-adrenal myelolipomas, most commonly in the presacral region. Read More

Curr Urol 2020 Jun 23;14(2):85-91. Epub 2020 Jun 23.

Assiut Urology and Nephrology Hospital, Faculty of Medicine.

Objectives: To present our center's experience in the management of adrenal myelolipoma in the context of shifting from the open to the laparoscopic adrenalectomy approach.

Materials And Methods: A retrospective search of our center's records was done for reported cases of adrenal myelolipoma during the period July 2001-June 2016. All the cases with histopathologically-documented adrenal myelolipoma diagnosis were included. Read More

P R Health Sci J 2020 06;39(2):226-228

Department of General Surgery, School of Medicine, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico.

Adrenal incidentalomas are tumors located in the adrenal glands and found on imaging done for purposes not related to adrenal disease. In other cases adrenal mases can be radiologically found when an adrenal hormone secreting tumor is suspected, such as a pheochromocytoma or Cushing's diseases. Adrenal incidentalomas may be classified as functional or non-functional based on whether they produce hormones, such as aldosterone, cortisol, and androgens, or catecholamines. Read More

J Int Med Res 2020 Jul;48(7):300060520936972

Department of Pathology, Shanxi Provincial People's Hospital, Taiyuan, Shanxi, China.

Background: Mediastinal myelolipoma is extremely rare. It is a benign nonfunctioning tumor composed of hematopoietic tissue and mature fatty tissue. Although computed tomography and magnetic resonance imaging are effective in diagnosing mediastinal myelolipoma, a definitive diagnosis is difficult to establish for rare extra-adrenal myelolipomas by imaging alone. Read More

BMJ Case Rep 2020 Jun 11;13(6). Epub 2020 Jun 11.

Baylor College of Medicine, Houston, Texas, USA

Macroscopic fat inside an adrenal lesion on CT is pathognomonic for myelolipoma, a benign neoplasm. Without macroscopic fat, it can be difficult to discern the nature of an indeterminate adrenal mass on imaging. One possible diagnosis for an indeterminate lesion without macroscopic fat is an adrenal oncocytic neoplasm (AON). Read More

Int J Surg Case Rep 2020 1;72:63-65. Epub 2020 Jun 1.

Department of Surgery, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia.

Introduction: Adrenal myelolipoma is a rare, non-functional, benign neoplasm which is constituted of mature haematopoietic elements and adipose tissues in various proportions. It is diagnosed accidentally and frequently with the widespread use of imaging modalities.

Presentation Of Case: We report a 63-year-old lady with incidental findings of adrenal tumour on computed tomography (CT) scan during a routine medical check-up. Read More

J Vasc Interv Radiol 2020 Jun;31(6):977

Department of Radiology, Santa Barbara Cottage Hospital, 400 West Pueblo Street, Santa Barbara, CA 93105.

Radiol Case Rep 2020 Jul 7;15(7):961-965. Epub 2020 May 7.

Department of Radiology, Section of Vascular and Interventional Radiology, University of Missouri, One Hospital Drive, Columbia, MO 65212, USA.

Adrenal myelolipoma is a benign tumor of the adrenal cortex composed predominantly of fat and hematopoietic tissue. These lesions are usually asymptomatic, and most often incidentally detected on imaging. Uncommonly, they present with retroperitoneal hemorrhage, and these have been traditionally treated with emergent surgery. Read More

Endocr Pract 2020 Apr 27. Epub 2020 Apr 27.

Department of Endocrinology, Metabolism and Diabetes, Karolinska University Hospital, Stockholm, Sweden.

The prevalence of adrenal tumors in congenital adrenal hyperplasia (CAH) is uncertain. To estimate the prevalence and characteristics of adrenal tumors and myelolipoma in CAH, and investigate clinical features of this population. Systematically searches in Medline Ovid and Embase for articles published until January 2020. Read More

Clin Endocrinol (Oxf) 2020 07 23;93(1):11-18. Epub 2020 Apr 23.

Division of Endocrinology, Diabetes, and Nutrition, Mayo Clinic, Rochester, MN, USA.

Objective: We aimed to describe clinical course of myelolipoma and to identify predictors of tumour growth and need for surgery.

Design: A retrospective study.

Patients: Consecutive patients with myelolipoma. Read More

Iran J Kidney Dis 2020 01;14(1):62-64

Department of Nephrology, Hormozgan University of Medical Sciences, Bandarabbas.

As a rare and normally-benign and functionless tumor, primary adrenal myelolipoma comprises adipose tissue and myeloid cells, and its diagnosis is usually difficult owing to its asymptomatic nature. Imaging techniques can detect these masses in over 90% of the cases. CT scan is the most sensitive imaging technique, which can display the tissue nature of this tumor with a high resolution. Read More

Pan Afr Med J 2019 5;34:180. Epub 2019 Dec 5.

Urology Department, Mohammed the Sixth University Hospital, Oujda, Morocco.

Adrenal myelolipoma (MLS) is a rare, benign and non-functional neoplasm, composed of adipose tissue and myeloid. We report a rare case of adrenal myelolipoma of a 20-year-old female revealed with chronic abdominal pain. Computed tomography (CT) scan of the abdomen guided diagnosis and surgical resection was performed given symptomatic and bulky mass. Read More

Cureus 2020 Jan 7;12(1):e6582. Epub 2020 Jan 7.

Urology, Korgialenio-Benakio Hellenic Red Cross Hospital, Athens, GRC.

Giant adrenal myelolipoma is a rare, benign, sizable, mesenchymal tumor. Preoperative differential diagnosis from retroperitoneal liposarcoma may be challenging. A 66-year-old female patient was admitted because of a sizable tumor at the right retroperitoneal space, incidentally discovered during abdominal ultrasonography for screening purpose. Read More

Hinyokika Kiyo 2020 Jan;66(1):5-8

The Department of Urology, Kitasato University School of Medicine.

We report a case of retroperitoneal mature teratoma which was successfully treated by laparoscopic adrenalectomy. A 37-year-old woman complaining of right abdominal discomfort was referred to our hospital because computed tomography showed an adrenal tumor at another hospital. Magnetic resonance imaging showed a 10 cm adrenal tumor that consisted of fat with calcification. Read More

Int J Surg Case Rep 2020 26;67:54-61. Epub 2020 Jan 26.

Department of General Surgery, Surgical Oncology Section, King Fahad Specialist Hospital-Dammam, Saudi Arabia.

Introduction: Lipomatous tumors of the adrenal glands are a diverse group of tumors characterized by the composition of adipose tissue. This group of tumors include myelolipomas, angiomyolipomas (AML), lipomas, and teratomas. They are usually benign, non-functioning tumors, and they account for 5% of all primary adrenal tumors. Read More

Pol Arch Intern Med 2020 03 24;130(3):249-251. Epub 2020 Jan 24.

Department of Endocrinology, Diabetes and Isotope Therapy, Wroclaw Medical University, Wrocław, Poland

Int J Clin Exp Pathol 2019 1;12(6):2302-2304. Epub 2019 Jun 1.

Department of Urology, The Affiliated Jiangning Hospital with Nanjing Medical University Nanjing, Jiangsu, China.

Adrenal collision tumor (ACT), where distinct tumors can coexist and do not intermingle in the same adrenal gland, is rarely reported and its cause and prevalence are unclear. Few papers have reported a connection between myelolipoma and adrenal ganglioneuroma. Case Report: A 40-year-old man had a physical examination one month prior to surgery. Read More

Medicine (Baltimore) 2020 Jan;99(2):e18387

Department of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, Republic of Korea.

Rationale: Congenital adrenal hyperplasia (CAH) is caused by various enzyme deficiencies, among which 21-hydroxylase (21-OH) deficiency accounts for more than 90% of cases. Neonatal screening became mandatory only a few decades ago. Many patients who were born before this went undiagnosed and some of the severely virilized females were raised as men. Read More