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Int J Biol Macromol 2019 Mar 12. Epub 2019 Mar 12.

Department of Microbiology, University College of Science, Tumkur University, Tumkur 572103, Karnataka, India. Electronic address:

The recent study deals with the synthesis and characterization of silver nanoparticles bounded to Selaginella bryopteris (Sanjeevini) Plant extract (SPE) as reducing and capping agents. Selaginella bryopteris plant extract silver nanoparticles (SPE@Ag-NPs) was characterized by PXRD, UV-Vis., FESEM, TEM and EDX. Read More

Endocrinol Diabetes Metab Case Rep 2019 Mar 15;2019. Epub 2019 Mar 15.

Department of Internal Medicine F, Soroka University Medical Center, Beer Sheva, Israel.

A previously healthy 24-year-old female underwent an emergent caesarean section without a major bleeding described. During the first post-operative days (POD) she complained of fatigue, headache and a failure to lactate with no specific and conclusive findings on head CT. On the following days, fever rose with a suspicion of an obstetric surgery-related infection, again with no evidence to support the diagnosis. Read More

J Forensic Leg Med 2019 Apr 5;63:52-55. Epub 2019 Mar 5.

The University of Adelaide Medical School, Frome Road, Adelaide, SA, 5005, Australia; Forensic Science SA, 21 Divett Place, Adelaide, SA, 5000, Australia. Electronic address:

Clinical and pathological case files of lethal snakebites were reviewed from the XXXX, Magway, Myanmar, over a five-year period (January 2013 December 2017). A total of 2069 postmortem examinations were performed which included 84 cases of lethal snake bite (4.1%). Read More

J Clin Med 2019 Feb 25;8(2). Epub 2019 Feb 25.

Institute of New Frontier Stroke Research, Hallym University College of Medicine, Chuncheon 24252, Korea.

Genome-wide association studies found genetic variations with modulatory effects for intracranial aneurysm (IA) formations in European and Japanese populations. We aimed to identify the susceptibility of single nucleotide polymorphisms (SNPs) to IA in a Korean population consisting of 250 patients, and 294 controls using the Asian-specific Axiom Precision Medicine Research Array. Twenty-nine SNPs reached a genome-wide significance threshold (5 × 10). Read More

Radiol Bras 2019 Jan-Feb;52(1):12-16

Hospital Universitário Maria Aparecida Pedrossian da Universidade Federal de Mato Grosso do Sul (HUMAP-UFMS), Campo Grande, MS, Brazil.

Objective: To evaluate the computed tomography characteristics of patients admitted with clinical suspicion of acute adrenal hemorrhage at three centers over a 3-year period and in whom that diagnosis was ultimately confirmed.

Materials And Methods: This was a retrospective analysis of computed tomography findings in patients with suspected acute adrenal hemorrhage. We included only those cases in which the diagnosis was confirmed. Read More

Ugeskr Laeger 2019 Feb;181(7)

mail:

In this case report, we present a 28-year-old woman who was admitted to a neuro-intensive care unit with sub-arachnoid haemorrhage. She was intubated and haemodynamically unstable. Over five days the need for norepinephrine reached the level of 1. Read More

Medicine (Baltimore) 2019 Feb;98(6):e14354

Department of Ophthalmology and Visual Science, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Rationale: Increases in cosmetic laser use have led to recent reports of accidental retinal injuries, most of which are limited to the posterior pole. We report a case of peripheral retinal injury caused by a 1064-nm Nd:YAG: neodymium-doped yttrium aluminum garnet.

Patient Concerns: A 27-year-old Asian woman was admitted with scotoma symptoms in her right eye. Read More

J Surg Oncol 2019 Jan 30. Epub 2019 Jan 30.

Shanghai Key Laboratory for Endocrine Tumors, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of Chinese Health Ministry, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Background And Objectives: To clarify the correlation of variant venous anatomy with adrenal tumor phenotype and surgical outcomes.

Patients And Methods: This retrospective study included 303 consecutive minimally invasive adrenalectomies from 301 patients. All adrenal veins were identified. Read More

Health Sci Rep 2018 Mar 20;1(3):e22. Epub 2017 Dec 20.

Internal Medicine and Endocrinology, Department of Internal Medicine, Division of Endocrinology Cukurova University Medical Faculty Adana Turkey.

Background: Adrenal incidentalomas are adrenal masses that are discovered by imaging tests performed for other reasons.

Aims: In this retrospective study, we analysed 229 Turkish patients with adrenal masses and who presented with or without complaints.

Study Design: Descriptive retrospective study and review of the literature. Read More

Cochrane Database Syst Rev 2018 Dec 31;12:CD004328. Epub 2018 Dec 31.

Royal National Throat, Nose and Ear Hospital, 330 Gray's Inn Road, London, UK, WC1X 8DA.

Background: Epistaxis (nosebleed) most commonly affects children and the elderly. The majority of episodes are managed at home with simple measures. In more severe cases medical intervention is required to either cauterise the bleeding vessel, or to pack the nose with various materials. Read More

Eur J Obstet Gynecol Reprod Biol 2019 Feb 30;233:38-42. Epub 2018 Nov 30.

Obstetrics and Gynecology Department, Hôpital Femme Mère Enfant, Hospices Civils de Lyon, Lyon, France.

Objectives: Adrenal vein thrombosis during pregnancy is a rare thromboembolic event but is not exceptional. The objective of this study was to described the symptoms, diagnosis, treatment and follow-up of patients with this condition.

Study Design: This was a retrospective descriptive study of 14 cases (13 patients, one recurrence) that occurred in the three university maternity hospitals in Lyon (France) from 2008 to 2016. Read More

Exp Clin Endocrinol Diabetes 2019 Feb 18;127(2-03):165-175. Epub 2018 Dec 18.

Department of Medicine III, University Hospital Carl Gustav Carus, Dresden, Germany.

Addison's disease - the traditional term for primary adrenal insufficiency (PAI) - is defined as the clinical manifestation of chronic glucocorticoid- and/or mineralocorticoid deficiency due to failure of the adrenal cortex which may result in an adrenal crisis with potentially life-threatening consequences. Even though efficient and safe pharmaceutical preparations for the substitution of endogenous gluco- and mineralocorticoids are established in therapy, the mortality in patients with PAI is still increased and the health-related quality of life (HRQoL) is often reduced.PAI is a rare disease but recent data report an increasing prevalence. Read More

J Clin Apher 2019 Feb 8;34(1):44-50. Epub 2018 Dec 8.

Department of Molecular Medicine and Haematology, Faculty of Health Sciences, National Health Laboratory Service, University of the Witwatersrand, Johannesburg, South Africa.

Introduction: Thrombotic thrombocytopenic purpura (TTP) is associated with high mortality if not managed timeously with therapeutic plasma exchange (TPE). TTP secondary to human immunodeficiency virus (HIV) infection is unique to sub-Saharan Africa. The management and outcome of TTP in the era of improved access to therapy has not been described. Read More

Gland Surg 2018 Oct;7(5):428-432

Endocrine Surgery Unit, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.

Background: Acute adrenal haemorrhage is a rare medical emergency. The aim of the series was to study the clinical presentation and management of patients presenting with acute non-traumatic adrenal haemorrhage.

Methods: The records of patients presenting with an acute abdomen secondary to adrenal haemorrhage and treated in a tertiary endocrine surgical unit over a period of 6 years were reviewed. Read More

Can J Ophthalmol 2018 Dec 5;53(6):621-626. Epub 2018 Apr 5.

Department of Ophthalmology, McGill University, Montréal, Qué.

Objective: To characterize the ocular response to retrobulbar anaesthesia and to evaluate the efficacy of retrobulbar anaesthesia for adjustable strabismus surgery in adults.

Design: Prospective observational study.

Participants: Adult patients undergoing adjustable strabismus surgery under retrobulbar anaesthesia. Read More

Endocrinol Diabetes Metab Case Rep 2018 Nov 22;2018. Epub 2018 Nov 22.

Endocrinology, Diabetes and Metabolism Department, Centro Hospitalar e Universitario de Coimbra EPE, Coimbra, Portugal.

Addison's disease (AD) is the most common endocrine manifestation of antiphospholipid syndrome (APS), but it remains a very rare complication of the syndrome. It is caused by adrenal venous thrombosis and consequent hemorrhagic infarction or by spontaneous (without thrombosis) adrenal hemorrhage, usually occurring after surgery or anticoagulant therapy. We present a clinical case of a 36-year-old female patient with a previous diagnosis of APS. Read More

Dig Dis Sci 2019 01 26;64(1):283-284. Epub 2018 Nov 26.

Department of Cardiology, Shanghai Changzheng Hospital, Second Military Medical University, No. 415, Fengyang Road, Huangpu District, Shanghai, China.

Int J Mol Sci 2018 Nov 19;19(11). Epub 2018 Nov 19.

Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, No. 250, Wu Hsing St., Taipei 110, Taiwan.

Platelets play a major role in hemostatic events and are associated with various pathological events, such as arterial thrombosis and atherosclerosis. Iridium (Ir) compounds are potential alternatives to platinum compounds, since they exert promising anticancer effects without cellular toxicity. Our recent studies found that Ir compounds show potent antiplatelet properties. Read More

Medicine (Baltimore) 2018 Nov;97(47):e13329

Department of Radiology.

Rational: Spontaneous adrenal hematoma in pregnancy is a very rare condition. Herein we present an additional rare case of unilateral spontaneous adrenal hematoma in a pregnant woman, aiming to share this experience and summarize the signal characteristics of simple adrenal hematoma in magnetic resonance imaging (MRI).

Patient Concerns: A 28-year old pregnant woman was referred to our hospital with a vague paroxysmal left-side back pain at 17 weeks of gestation. Read More

BMC Surg 2018 Nov 20;18(1):103. Epub 2018 Nov 20.

Department of Clinical and Experimental Medicine, Unit of General Surgery 2, University of Sassari, Sassari, Italy.

Background: Adrenal cavernous hemangiomas are very rare benign tumors that usually present as incidental findings on abdominal imaging. Preoperative differential diagnosis from other benign or malignant adrenal neoplasms may be challenging.

Case Presentation: A 70-year old man was referred for an 8-cm abdominal mass incidentally discovered on a contrast-enhanced computed tomography (CT) performed to investigate a pulmonary nodule. Read More

Pediatr Clin North Am 2019 02;66(1):101-110

Department of Pediatrics, Medical University of South Carolina, 96 Jonathan Lucas Street, 428 CSB, MSC 608, Charleston, SC 29425, USA. Electronic address:

Henoch-Schönlein purpura nephritis and immunoglobulin A nephropathy are common glomerulopathies in the pediatric population that deserve special attention. In some cases the primary care provider can follow the patient but others need more intensive management. Delaying this treatment can lead to worse morbidity. Read More

Ann Hematol 2019 Mar 17;98(3):581-588. Epub 2018 Nov 17.

Division of Hematology, Massachusetts General Hospital, Zero Emerson Place, Harvard Medical School, Suite 118, Boston, MA, 02114, USA.

The thrombopoietin receptor agonist romiplostim is used for the long-term treatment of chronic immune thrombocytopenia (ITP). ITP patients have an increased thrombotic risk, which could be exacerbated if romiplostim increased platelet hyperreactivity or caused spontaneous platelet aggregation. To investigate this possibility, this study examined platelet function in romiplostim-treated ITP patients and healthy subjects. Read More

Orthop Surg 2018 Nov 8;10(4):287-295. Epub 2018 Nov 8.

Department of Orthopaedic Surgery, West China Hospital, West China Medical School, Sichuan University, Chengdu, China.

The present study assessed the effectiveness of the combined administration of tranexamic acid (TXA) plus low-dose epinephrine in primary total knee arthroplasty (TKA). We searched the following Chinese electronic databases: China National Knowledge Infrastructure and WanFang Data. We also searched the following English electronic databases: PubMed, Embase, Web of Science, and Central Register of Controlled Trials. Read More

Semin Respir Crit Care Med 2018 08 7;39(4):494-503. Epub 2018 Nov 7.

Department of Medicine, Centre for Inflammatory Disease, Imperial College London, London, United Kingdom.

Antiglomerular basement membrane (anti-GBM) disease is a rare but life-threatening autoimmune vasculitis that is characterized by the development of pathogenic autoantibodies to type IV collagen antigens expressed in the glomerular and alveolar basement membranes. Once deposited in tissue, these autoantibodies incite a local capillaritis which manifests as rapidly progressive glomerulonephritis (GN) in 80 to 90% of patients, and with concurrent alveolar hemorrhage in ∼50%. A small proportion of cases may present with pulmonary disease in isolation. Read More

Semin Respir Crit Care Med 2018 08 7;39(4):482-493. Epub 2018 Nov 7.

Department of Respiratory Medicine, Hospices Civils de Lyon, National Reference Center for Rare Pulmonary Diseases, Lyon, France.

Defined by the accumulation of red blood cells into the alveolar space, diffuse alveolar hemorrhage (DAH) is a severe and potentially fatal medical condition requiring careful attention. In contrast to simple extravasation of erythrocytes facilitated by impaired hemostasis or hemodynamic causes, DAH in vasculitis is due to capillaritis, that is, inflammation of capillaries. Dyspnea, hemoptysis, chest infiltrates, and abrupt fall of blood hemoglobin level represent the cardinal features of DAH; yet, hemoptysis is lacking in one-third of cases. Read More

Semin Respir Crit Care Med 2018 08 7;39(4):434-458. Epub 2018 Nov 7.

Division of Pulmonary, Critical Care Medicine, Allergy and Clinical Immunology, Department of Medicine, The David Geffen School of Medicine at UCLA, Los Angeles, California.

Granulomatosis with polyangiitis (GPA), formerly termed , is the most common of the pulmonary vasculitides. GPA typically involves the upper respiratory tract, lower respiratory tract (bronchi and lung), and kidney, with varying degrees of disseminated vasculitis. Cardinal histologic features include a necrotizing vasculitis involving small vessels, extensive "geographic" necrosis, and granulomatous inflammation. Read More

Pan Afr Med J 2018 13;30:121. Epub 2018 Jun 13.

Katutura State Hospital, UNAM School of Medicine, Windhoek, Namibia.

Tuberculosis is still one of the most common respiratory diseases in Africa and worldwide and miliary tuberculosis is a regular manifestation of it. Idiopathic pulmonary hemosiderosis is a rare disease entity, presenting in children as well as adults. It is characterized by the triad of recurrent episodes of alveolar hemorrhage, presenting as hemoptysis, iron deficiency anemia and bilateral pulmonary infiltrates seen on chest X-ray. Read More

Endokrynol Pol 2018 Oct 23. Epub 2018 Oct 23.

Clinic for Endocrinology, Diabetes and Metabolic Diseases, University Clinical Center, Belgrade, Serbia; Medical Faculty, University of Belgrade, Belgrade, Serbia.

Pheochromocytomas and sympathetic paragangliomas are rare catecholamine-secreting tumors and represent very rare causes of intracerebral hemorrhage in young, with only few cases reported. A 32-year-old man presented to our emergency department because of sudden onset of severe headache. He had a six months history of paroxysmal headache, palpitations and sweating. Read More

Clin Endocrinol (Oxf) 2019 Jan 15;90(1):74-78. Epub 2018 Nov 15.

Departments of Transplant and Endocrine Surgery, Manchester Royal Infirmary, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.

Objective: Adrenal surgery remains a distinct surgical challenge. Technical challenges associated with laparoscopic adrenalectomy are tumour size, haemorrhage control and oncological compromise. Hand-assisted laparoscopic (HAL) adrenalectomy, utilizing a hand-port device, offers minimally invasive surgery with the advantages and safety of tactile feedback. Read More

Rev Med Interne 2018 Dec 10;39(12):942-945. Epub 2018 Oct 10.

Service de Néphrologie, de dialyse et de transplantation rénale, CHU La Rabta, Tunis, Tunisie; Faculté de Médecine de Tunis, Université Tunis El Manar, Tunis, Tunisie.

Introduction: Iatrogenic Kaposi's sarcoma is widely reported after transplantation. Less commonly, it occurs in patients receiving immunosuppressive therapy for ANCA associated vasculitis. We report here the rare association of Kaposi's sarcoma, prurigo nodularis and ANCA associated vasculitis in a hemodialysis patient. Read More

Wilderness Environ Med 2018 Dec 8;29(4):504-507. Epub 2018 Oct 8.

Department of Internal Medicine, Trichy SRM Medical College Hospital and Research Center, Irungalur, Trichy, India (Prof Thirumalaikolundusubramanian).

Snakebite envenomation is an important public health problem in tropical countries. We report a case of bilateral adrenal hemorrhage in a 28-y-old man with Russell's viper bite that occurred in the Sathyamangalam forest range in the Indian state of Tamil Nadu. In this case, a combination of early bite recognition, hospital-based supportive care, corticosteroid therapy, and timely administration of polyvalent antivenom resulted in a favorable clinical outcome. Read More

Endocrinol Diabetes Metab Case Rep 2018 Sep 25;2018. Epub 2018 Sep 25.

Endocrinology, Niguarda Hospital, Milan, Italy

A 69-year-old male was admitted for severe hyponatremia disclosed after an accidental fall. He was anticoagulated from 2 months after the implantation of a biologic aortic valve prosthesis. The work-up disclosed adrenal failure and MRI showed bilateral adrenal hemorrhage. Read More

Quant Imaging Med Surg 2018 Sep;8(8):853-875

Department of Radiology, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, China.

Besides ultrasound and nuclear medicine techniques, computed tomography (CT) and magnetic resonance imaging (MRI) are commonly used to examine adrenal lesions in both symptomatic and asymptomatic patients. Some adrenal lesions have characteristic radiological features. If an adrenal nodule is discovered incidentally, determining whether the lesion is benign or malignant is of great importance. Read More

J Laryngol Otol 2018 Oct 9;132(10):911-922. Epub 2018 Oct 9.

Department of Otorhinolaryngology - Head and Neck Surgery,Turku University Hospital,Finland.

Objectives: In order to evaluate the safety of tonsillectomy among children, we retrospectively studied the incidence of post-operative complications, adverse events and their association with peri-operative medication.

Methods: Data were collected from the medical records of 691 patients aged 1-16 years, including details of post-operative complications (any unplanned contact with the hospital), analgesics, dexamethasone, 5-HT3 antagonists, local anaesthetic and haemostatic agents.

Results: Recovery was complicated in 13. Read More

J Med Case Rep 2018 Oct 8;12(1):295. Epub 2018 Oct 8.

Department of General Internal Medicine, Musashino Red Cross Hospital, Tokyo, Japan.

Background: TAFRO syndrome, which was first reported in 2010 in Japan, is a relatively rare disease characterized by thrombocytopenia, anasarca, fever, renal impairment, reticulin fibrosis, and organomegaly. Although this disease is considered similar to multicentric Castleman disease, some of the clinical features, such as thrombocytopenia, are different from typical cases of multicentric Castleman disease. In addition, the etiology of TAFRO syndrome remains unknown and controversial. Read More

Acta Chir Belg 2018 Oct 1:1-5. Epub 2018 Oct 1.

a Departments of Critical Care Medicine, Hepatobiliary, Transplantation and Endocrine Surgery , Antwerp University Hospital University of Antwerp , Edegem , Belgium.

Most adrenal injuries are asymptomatic. In traumatic events, adrenal haemorrhage is very likely to be accompanied by injuries to other organs. Isolated adrenal injury after trauma is very rare and mostly unilateral. Read More

J Obstet Gynaecol Can 2018 Sep;40(9):1219-1239

Vancouver, BC.

Objective: To assess the benefits and risks of antenatal corticosteroid therapy for women at risk of preterm birth or undergoing pre-labour Caesarean section at term and to make recommendations for improving neonatal and long-term outcomes.

Options: To administer or withhold antenatal corticosteroid therapy for women at high risk of preterm birth or women undergoing pre-labour Caesarean section at term.

Outcomes: Perinatal morbidity, including respiratory distress syndrome, intraventricular hemorrhage, bronchopulmonary dysplasia, infection, hypoglycemia, somatic and brain growth, and neurodevelopment; perinatal mortality; and maternal morbidity, including infection and adrenal suppression. Read More

Wiad Lek 2018;71(6):1284-1287

Department Of Internal Medicine And Infectious Diseases, Higher State Educational Establishment "Bukovinian State Medical University", Chernivtsi, Ukraine.

Meningococcal infection remains a leading cause of morbidity and mortality. Based on the sequence of pathophysiological mechanisms and the agent and host factors, a wide spectrum of presentations may be seen. Here we report a non-fatal case of fulminant form of meningococcemia beginning as food poisoning complicated with shock I degree due to partially adrenal hemorrhage in Caucasian adult male. Read More

BJOG 2019 Jan 27;126(1):e49-e61. Epub 2018 Sep 27.

Acta Clin Croat 2018 Mar;57(1):161-165

Department of Pediatrics, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia.

Adrenal hemorrhage is a rare clinical entity in the neonatal period, with an incidence of 1.7-2.1/1000 births. Read More

Vet Surg 2018 Nov 23;47(8):1031-1038. Epub 2018 Sep 23.

Department of Surgical and Radiological Sciences, University of California-Davis, Davis, California.

Objective: To compare anatomic sources and underlying etiology of hemorrhage in small vs large dogs with spontaneous hemoperitoneum (SH).

Study Design: Retrospective cross-sectional study.

Animals: Client-owned dogs with SH at 2 academic institutions. Read More

J Orthop Surg Res 2018 Sep 21;13(1):242. Epub 2018 Sep 21.

Department of Orthopaedics, The 82rn Hospital of People's Liberation Army of China, No. 100, Jiankangdong Road, Huai'an, Jiangsu, China.

Background: The standard protocol to achieve haemostasis during total hip arthroplasty (THA) is uncertain. Tranexamic acid plus diluted epinephrine (DEP) and tranexamic acid (TXA) alone are the two most common alternatives. The purpose of this study was to compare the efficacy and safety of TXA plus DEP to treat blood loss in THA patients. Read More

J Stroke Cerebrovasc Dis 2018 Nov 12;27(11):3163-3171. Epub 2018 Sep 12.

Department of Neurology, CHU de Bordeaux, Bordeaux, France / Except Yahsou Delmas: Department of Nephrology, CHU de Bordeaux, Bordeaux, France.

Introduction: Immune thrombotic thrombocytopenic purpura (i-TTP), related to acquired ADAMTS-13 dysfunction, can lead to various neurological symptoms including ischemic stroke. To date the clinical, radiological, and biological characteristics of patients having a stroke as the inaugural manifestation of i-TTP are largely unknown.

Methods: Probable immune-TTP was defined by a low ADAMTS-13 activity associated with the presence of ADAMTS-13 inhibitors and/or favorable clinicobiological response under immunological treatments. Read More

Int J Endocrinol Metab 2018 Jul 25;16(3):e65233. Epub 2018 Jun 25.

The Diabetes and Endocrine Unit, Department of Medicine, National University of Malaysia Medical Centre, Kuala Lumpur, Malaysia.

Introduction: Ketoconazole has long been the first-line medical therapy for controlling hypercortisolism secondary to either pituitary or adrenal pathology. However, it is largely unavailable in most countries. As a result, we have turned to fluconazole as a viable alternative in view of its favourable safety profile. Read More

Quintessence Int 2018 ;49(9):719-732

The purpose of this topic review is to give a general overview of gingival retraction agents used during prosthodontic treatment, and the possible difficulties connected to them that may be faced by the dentist. Hemostatic agents are important for successful gingival retraction and in achieving hemostasis. However, these agents may show numerous negative effects on the prosthodontic treatment and oral tissues of which the practicing dentist must be aware, and which will be elucidated in this review. Read More

J Emerg Med 2018 10 6;55(4):455-464. Epub 2018 Sep 6.

Department of Emergency Medicine, Mayo Clinic, Rochester, Minnesota.

Background: Treatment for epistaxis includes application of intranasal vasoconstrictors. These medications have a precaution against use in patients with hypertension. Given that many patients who present with epistaxis are hypertensive, these warnings are commonly overridden by clinical necessity. Read More

Clin Orthop Surg 2018 Sep 22;10(3):380-384. Epub 2018 Aug 22.

Department of Orthopedics, Seoul Sacred Heart General Hospital, Seoul, Korea.

Background: The incidence of cardiovascular and neurovascular diseases has been increasing with the aging of the population, and antiplatelet drugs (APDs) are more frequently used than in the past. With the average age of spinal surgery patients also increasing, there has been a great concern on the adverse effects of APD on spine surgery. To our knowledge, though there have been many studies on this issue, their results are conflicting. Read More

Am J Case Rep 2018 Aug 28;19:1025-1029. Epub 2018 Aug 28.

Department of Pulmonary and Critical Care Medicine, China Medical University Hospital, Taichung, Taiwan.

BACKGROUND Aortoesophageal fistula is a rare etiology of serious gastrointestinal bleeding. Most aortoesophageal fistulas resulted from thoracic aortic aneurysms, foreign bodies, or esophageal malignancy. To our knowledge, spontaneous aortoesophageal fistula due to dermatomyositis and high dose steroid therapy has not been reported. Read More

Int J Surg Case Rep 2018 17;51:90-94. Epub 2018 Aug 17.

4th Surgical Department, Evaggelismos General Hospital, Athens, Greece.

Introduction: Spontaneous bilateral adrenal hemorrhage or hemorrhagic necrosis due to adrenal vein thrombosis is an uncommon condition that may lead to acute adrenal insufficiency and death. The objective of this report is to enhance recognition of this potentially fatal disorder in surgical patients.

Presentation Of Cases: We present two cases of acute adrenal insufficiency due to bilateral adrenal hemorrhage associated with primary antiphospholipid antibody syndrome (APS). Read More