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    1 OF 145

    [Adrenal myelolipoma: about a case].
    Pan Afr Med J 2017 18;28:153. Epub 2017 Oct 18.
    Service d'Endocrinologie Diabétologie Maladies Métaboliques et Nutrition, Laboratoire PCIM, FMPM, Université Cadi Ayyad, CHU Mohamed VI, Marrakech.
    Adrenal myelolipoma is a rare benign non secreting tumor. It is often unexpectedly detected. Pathophysiologically, it is adrenal cortex cell metaplasia into reticuloendothelial cells, resulting from infection, chronic stress or adrenal gland degeneration. Read More

    Routine CT scanning of patients retrieved to a tertiary centre on veno-venous extracorporeal membrane oxygenation: a retrospective risk benefit analysis.
    Perfusion 2018 Mar 1:267659118763266. Epub 2018 Mar 1.
    1 Department of Intensive Care, Royal Brompton Hospital, London, UK.
    Introduction: Comprehensive clinical examination can be compromised in patients on veno-venous extracorporeal membrane oxygenation (VV-ECMO). Adjunctive diagnostic imaging strategies range from bedside imaging only to routine computed tomography (CT). The risk-benefit of either approach remains to be evaluated. Read More

    Acute Primary Adrenal Insufficiency after Hip Replacement in a Patient with Acute Intermittent Porphyria.
    Case Rep Endocrinol 2018 4;2018:2353172. Epub 2018 Jan 4.
    Division of Endocrinology, Diabetology and Metabolism, Santa Croce e Carle Hospital, Via M. Coppino 26, 12100 Cuneo, Italy.
    Adrenal insufficiency is a potentially life-threatening condition when it occurs acutely, as in adrenal hemorrhage. Generally it is not reversible and requires chronic replacement therapy. Acute intermittent porphyria (AIP) is a rare genetic disease characterized by alterations in heme biosynthesis that result in accumulation of precursors in tissues. Read More

    Severe bilateral adrenal hemorrhages in a newborn complicated by persistent adrenal insufficiency.
    Endocrinol Diabetes Metab Case Rep 2018 20;2018. Epub 2018 Feb 20.
    Pediatrics and Radiology, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA.
    Bilateral adrenal hemorrhages rarely occur during the neonatal period and are often associated with traumatic vaginal deliveries. However, the adrenal gland has highly regenerative capabilities and adrenal insufficiency typically resolves over time. We evaluated a newborn female after experiencing fetal macrosomia and a traumatic vaginal delivery. Read More

    Acute pituitary disease in pregnancy: how to handle hypophysitis and Sheehan's syndrome?
    Minerva Endocrinol 2018 Feb 19. Epub 2018 Feb 19.
    Department of Neurosurgery, University of Tübingen, Tübingen, Germany.
    Pregnancy-related hypophysitis (PR-Hy) that typically occurs during late pregnancy and the early postpartum period is considered an autoimmune disorder. Knowledge and awareness of characteristic clinical symptoms and specific endocrine and neuroradiological features mostly enables a correct diagnosis and guarantees best possible management. In the presence of mild clinical symptoms, a "wait and watch" policy is recommended. Read More

    Acute Nonhemorrhagic Adrenal Infarction in Pregnancy: 10-Year MRI Incidence and Patient Outcomes at a Single Institution.
    AJR Am J Roentgenol 2018 Feb 15:1-7. Epub 2018 Feb 15.
    1 Department of Radiology, Brigham and Women's Hospital, 75 Francis St, Boston, MA 02115.
    Objective: The purpose of this study was to retrospectively investigate the MRI incidence of nonhemorrhagic adrenal infarction in pregnant women undergoing MRI evaluation of acute abdominal or flank pain, assess the MRI features quantitatively, and report patient outcomes.

    Materials And Methods: All abdominal MRI examinations of pregnant women with acute pain at one institution from May 2005 to April 2015 were reviewed. The adrenals were evaluated for abnormal morphologic and signal intensity characteristics described in the literature characterizing nonhemorrhagic adrenal infarction and were compared with the contralateral adrenal by paired t tests. Read More

    Osmotic therapies added to antibiotics for acute bacterial meningitis.
    Cochrane Database Syst Rev 2018 02 6;2:CD008806. Epub 2018 Feb 6.
    Division of Infection and Immunity, University College London, Gower Street, London, UK, WC1E 6BT.
    Background: Every day children and adults die from acute community-acquired bacterial meningitis, particularly in low-income countries, and survivors risk deafness, epilepsy and neurological disabilities. Osmotic therapies may attract extra-vascular fluid and reduce cerebral oedema, and thus reduce death and improve neurological outcomes.This is an update of a Cochrane Review first published in 2013. Read More

    A case report of spontaneous staphylococcal meningitis in a cynomolgus monkey.
    J Med Primatol 2018 Apr 5;47(2):132-135. Epub 2018 Feb 5.
    National Institute for Food and Drug Control, National Center for Safety Evaluation of Drugs, Beijing Key Lab for Pre-clinical Safety Evaluation of Drugs, Beijing, China.
    This report describes a suppurative meningitis in a young cynomolgus. The animal had neutrophil aggregation in the subarachnoid space and hemorrhage in bilateral adrenal glands. Staphylococcus was identified by FISH in brain. Read More

    Beneficial Effects of Adrenal Androgen Supplement in Bleeding Cirrhotic Rats.
    Shock 2018 Feb 1. Epub 2018 Feb 1.
    Division of Gastroenterology, Department of Medicine, Cheng Hsin General Hospital, Taipei, Taiwan.
    Critical illness is accompanied by hypothalamic-pituitary-adrenal axis activation, but adrenal insufficiency characterized by inadequate glucocorticoid synthesis is common in critically ill cirrhotic patients, the 'hepato-adrenal syndrome'. Adrenal cortex also synthesizes androgen (dehydroepiandrosterone, DHEA). DHEA maintains microcirculation by enhancing vascular endothelial nitric oxide synthase (eNOS) activity. Read More

    A Rare Case Report of Bilateral Complex Macrocystic Adrenal Hemorrhage Mimicking Fetal Neuroblastoma.
    J Indian Assoc Pediatr Surg 2018 Jan-Mar;23(1):42-44
    Department of Urology, Muljibhai Patel Urological Institute, Nadiad, Gujarat, India.
    Fetal and neonatal adrenal glands are large vascular organs, which make them vulnerable to frequent bleeding. Although neonatal adrenal hemorrhage is commonly reported, it is rarely diagnosed on antenatal sonography. We present a rare case of prenatally diagnosed bilateral adrenal hemorrhage, which mimicked antenatal neuroblastoma. Read More

    Neurofibromatosis type 1: a case highlighting pulmonary and other rare clinical manifestations.
    BMJ Case Rep 2018 Jan 31;2018. Epub 2018 Jan 31.
    Department of Medicine, Pulmonary Critical Care and Sleep Medicine, University of California Los Angeles David Geffen School of Medicine, Los Angeles, California, USA.
    Neurofibromatosis type 1 (NF1)-related lung disease is a rare but increasingly recognised, high morbidity associated feature of the condition. We present a 48-year-old male patient with NF1, who was initially admitted for a subarachnoid haemorrhage requiring aneurysmal coil embolisation. During his recovery, he developed a left-sided pneumothorax requiring chest tube placement followed by concerns for re-expansion pulmonary oedema requiring intubation. Read More

    Acute duodenal intramural hematoma complicated by acute pancreatitis-a rare complication of endoscopic epinephrine injection therapy.
    Oxf Med Case Reports 2018 Jan 23;2018(1):omx090. Epub 2018 Jan 23.
    Department of Internal Medicine, SBH Health System, Bronx, NY 10457,USA.
    Intramural duodenal hematoma (IDH) is a rare complication in endoscopic management of ulcer hemorrhage. Usually noted in cases of blunt abdominal trauma, non-traumatic IDHs have been reported in individuals on anticoagulation, with blood disorders, pancreatic diseases and in endoscopic procedures such as biopsy, sclerotherapy and argon plasma coagulation. Patients may be asymptomatic or present with acute blood loss anemia, abdominal pain or vomiting. Read More

    Long-term efficacy of partial splenic embolization for the treatment of steroid-resistant chronic immune thrombocytopenia.
    Ann Hematol 2018 Apr 13;97(4):655-662. Epub 2018 Jan 13.
    Department of Hematology, Chiba University Hospital, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8677, Japan.
    Thrombopoietin-receptor agonists have been recently introduced for a second-line treatment of immune thrombocytopenia (ITP). Splenectomy has tended to be avoided because of its complications, but the response rate of splenectomy is 60-80% and it has still been considered for steroid-refractory ITP. We performed partial splenic embolization (PSE) as an alternative to splenectomy. Read More

    Bilateral Adrenal Hemorrhage in a Patient with Antiphospholipid Syndrome During Chronic Graft-versus-host Disease.
    Intern Med 2017 Dec 27. Epub 2017 Dec 27.
    Department of Endocrinology, Japan Community Health Care Organization (JCHO) Kyushu Hospital, Japan.
    We present the case of a 56-year-old man with an upper respiratory infection followed by fatigue, hypotension, and hyponatremia. Bilateral adrenal hemorrhage was confirmed, based on T2-weighted magnetic resonance imaging. The patient had previously undergone allogeneic hematopoietic stem cell transplantation and had been diagnosed with antiphospholipid syndrome (APS) during the development of chronic graft-versus-host disease. Read More

    Isolated unilateral adrenal gland hemorrhage following motor vehicle collision: a case report and review of the literature.
    J Med Case Rep 2017 Dec 26;11(1):358. Epub 2017 Dec 26.
    Department of General Surgery, Henry Ford Wyandotte Hospital, 2333 Biddle Ave, Wyandotte, MI, 48192, USA.
    Background: Adrenal gland trauma is a rare condition that typically stems from blunt force trauma, and is associated with multiple organ injuries. Alternatively, isolated adrenal gland trauma is extremely rare, accounting for only 1.5 to 4% of all adrenal trauma cases. Read More

    Pulmonary tumor thrombotic microangiopathy successfully treated with corticosteroids: a case report.
    J Med Case Rep 2017 Dec 23;11(1):356. Epub 2017 Dec 23.
    Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8560, Japan.
    Background: Pulmonary tumor thrombotic microangiopathy is a special type of tumor thromboembolism. We report the case of a patient who developed pulmonary tumor thrombotic microangiopathy with alveolar hemorrhage. Almost all patients with pulmonary tumor thrombotic microangiopathy die within 1 week of the onset of dyspnea; however, the prognosis in this case was better, with 10 weeks of survival from presentation. Read More

    Primary atrial fibromyxosarcoma with multiple-system metastases: A case report.
    Medicine (Baltimore) 2017 Dec;96(49):e8930
    aDepartment of Radiation OncologybDepartment of PathologycDepartment of Cardiac Surgery, the First Hospital, China Medical University, Shenyang, China.
    Rationale: Fibromyxosarcoma is common in head and neck, vessel, omentum, and reproductive system, with low-grade malignant behavior. However, primary atrial fibromyxosarcoma with highly malignant behavior is extremely rare.

    Patient Concerns: A 34-year-old female presented with oppression in the chest, short breath, and onset of headache as initial symptoms. Read More

    Unilateral aggressive pheochromocytoma revealed by a massive intraperitoneal hemorrhage five years after an initial presentation suggesting an adrenal hematoma.
    Ann Endocrinol (Paris) 2018 Feb 11;79(1):48-52. Epub 2017 Dec 11.
    Département d'endocrinologie, diabétologie et médecine de la reproduction, hôpital de l'Archet 2, CHU de Nice, 151, route de Saint-Antoine de Ginestière, CS 23079, 06202 Nice cedex 3, France.

    Persistent Primary Aldosteronism Despite Iatrogenic Adrenal Hemorrhage After Adrenal Vein Sampling.
    J Clin Med Res 2018 Jan 1;10(1):66-71. Epub 2017 Dec 1.
    Department of Cardiovascular Diseases, Fukuoka University Chikushi Hospital, Japan.
    Before surgery for primary aldosteronism (PA), localization is evaluated with adrenal vein sampling (AVS). A 56-year-old Japanese woman had a right adrenal mass, hypokalemia, and a high aldosterone/renin ratio. Stress tests confirmed the diagnosis of PA. Read More

    Pseudomesotheliomatous carcinoma of the pleura: an autopsy case of metastasis from a G-CSF-producing anaplastic carcinoma of the pancreas.
    APMIS 2017 Dec 13. Epub 2017 Dec 13.
    Department of Molecular Pathology, Graduate school of Biomedical and Health Sciences Hiroshima University, Hiroshima, Japan.
    Pseudomesotheliomatous carcinoma is a malignant tumor that extends along the pleura mimicking malignant mesothelioma. An 81-year-old male patient presented to our hospital with epigastralgia, and abdominal computed tomography (CT) showed a 36-mm tumor in the pancreatic tail. The laboratory data revealed a high leukocyte count (>44 000/μL). Read More

    Evaluation and Management of Blunt Solid Organ Trauma.
    Tech Vasc Interv Radiol 2017 Dec 10;20(4):230-236. Epub 2017 Nov 10.
    Division of Interventional Radiology and Image-guided Medicine, Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA.
    Trauma is a leading cause of death in patients under the age of 45 and generally associated with a high kinetic energy event such as a motor vehicle accident or fall from extreme elevations. Blunt trauma can affect every organ system and major vascular structure with potentially devastating effect. When we consider abdominal solid organ injury from blunt trauma, we usually think of the liver, spleen, and kidneys. Read More

    A rare case of Waterhouse- Friderichsen syndrome during primary Varicella zoster infection.
    Neth J Med 2017 Oct;75(8):351-353
    Department of Internal Medicine, Haaglanden Medical Centre, The Hague, the Netherlands.
    Primary Varicella zoster virus infection in adults is associated with a higher risk of complications when compared with the benign disease course of primary infection during childhood. We present a rare complication of adult primary Varicella zoster in the form of acute, irreversible adrenal insufficiency due to bilateral adrenal haemorrhage, which is also known as the WaterhouseFriderichsensyndrome. Read More

    Antenatal corticosteroids in impending preterm deliveries before 25 weeks' gestation.
    Arch Dis Child Fetal Neonatal Ed 2018 Mar 5;103(2):F173-F176. Epub 2017 Dec 5.
    Department of Neonatal Pediatrics, King Edward Memorial Hospital, Perth, Western Australia, Australia.
    Antenatal corticosteroid (ANC) use before 25 weeks' gestation is controversial. Our previous systematic review (eight observational studies, n=10 109) showed that ANC exposure was associated with significantly reduced mortality and severe intraventricular haemorrhage (IVH)/periventricular leukomalacia (PVL) in neonates born <25 weeks. We update our review by adding data (n=3334) from a recent study. Read More

    Fetal adrenal gland enlargement - prenatal and postnatal management.
    Neuro Endocrinol Lett 2017 Nov;38(Suppl1):31-34
    St. Elisabeth University of Health and Social Sciences, Bratislava, Slovakia.
    Background: The enlargement of suprarenal gland is related to preterm birth and the birth weight. The ultrasound measurement of fetal adrenal gland volume may identify women at risk for impending preterm birth. The aim of our study was to investigate the newborns in the region of western Slovakia followed up due to suprarenal gland enlargement. Read More

    Intra-articular corticosteroid injections in haemophilic arthropathy: are they recommended?
    Hosp Pract (1995) 2018 Feb 30;46(1):1-4. Epub 2017 Nov 30.
    a Department of Orthopaedic Surgery , La Paz University Hospital-IdiPaz , Madrid , Spain.
    Introduction: Intra-articular (IA) corticosteroid (CS) injections are commonly used in the treatment of osteoarthritis. However, they are rarely utilized in haemophilic arthropathy. In fact, the efficacy of this method in haemophilic arthropathy is frequently discussed and debated in clinical practice. Read More

    A case report of primary adrenal angiosarcoma as depicted on magnetic resonance imaging.
    Medicine (Baltimore) 2017 Nov;96(45):e8551
    aDepartment of Radiology, Sichuan Cancer Hospital and Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China bDepartment of Pathology, Sichuan Cancer Hospital and Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China cDepartment of Urology, Sichuan Cancer Hospital and Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan China.
    Rationale: Angiosarcoma is an extremely rare malignant tumor of endothelial origin. The majority of studies reporting angiosarcoma have been concerned with the clinical and pathological aspects, with limited reporting of their imaging findings. To our knowledge, angiosarcoma of the adrenal gland is very rare. Read More

    Post-stroke depression: Mechanisms and pharmacological treatment.
    Pharmacol Ther 2018 Apr 9;184:131-144. Epub 2017 Nov 9.
    Laboratory of Pharmacology and Molecular Medicine of Central Nervous System, Department of Biology and Biotechnology, University of Pavia, Italy.
    Depression, the most frequent psychiatric disorder following ischaemic stroke, negatively affects survivals' functional outcome, response to rehabilitation and quality of life. Approximately, one-third of them are affected by post-stroke depression (PSD), making it a serious social and public health problem and anti-depressant preventive and curative therapies worth investigating. However, a two-way association between depression and stroke has been also established: stroke increases the risk of PSD, but depression is an independent risk factor for stroke. Read More

    Patients' comorbidities reduce the clinical value of emergency colonoscopy: results of a retrospective cohort study.
    Endosc Int Open 2017 Nov 8;5(11):E1119-E1127. Epub 2017 Nov 8.
    EC2M3: Department of Academic Research (EA7375) Université Paris Est Créteil (UPEC) - Val de Marne, France.
    Background And Study Aims:  Urgent endoscopy is often used to diagnose and sometimes treat acute upper gastrointestinal syndromes (hemorrhage, toxic ingestion, and occlusion). However, its suitability concerning the management of lower gastrointestinal conditions in emergency circumstances is controversial.

    Patients And Methods:  We studied the role of emergency colonoscopy in diagnosis and treatment of all consecutive patients presenting with acute lower gastrointestinal symptoms referred to our hospital on an emergency basis. Read More

    Successful Treatment of Iatrogenic External Iliac Artery Perforation With Covered Stent: Case Report and Review of the Literature.
    Cardiol Res 2017 Oct 27;8(5):246-253. Epub 2017 Oct 27.
    Division of Cardiology, University of South Alabama, Mobile, AL 36617, USA.
    Retroperitoneal hemorrhage from iliac artery injury is a potentially serious complication of vascular interventional procedures leading to hemorrhagic shock and death if not diagnosed early and treated promptly. We report a 70-year-old male admitted to our facility with non-ST-elevation myocardial infarction, whose heart catheterization revealed left anterior descending artery (LAD) with 80% proximal, 95% mid and 100% distal disease. The left circumflex and right coronary arteries were 100% occluded proximally and received collaterals from the LAD. Read More

    Intraparenchymal Hemorrhage due to Brain Metastasis of Hepatocellular Carcinoma.
    Case Rep Gastroenterol 2017 Sep-Dec;11(3):516-525. Epub 2017 Sep 13.
    Faculty of Medicine, Universidade de Caxias do Sul, Caxias do Sul, Brazil.
    Although extrahepatic metastases from hepatocellular carcinoma (HCC) are present in only 5-15% of cases, they are certainly factors associated with poor prognosis. The main sites include lung, lymph nodes, bones, and adrenal glands, in descending order. Metastasis in the central nervous system is extremely rare, and the incidences vary from 0. Read More

    Imaging of Nonmalignant Adrenal Lesions in Children.
    Radiographics 2017 Oct;37(6):1648-1664
    From the Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 S Kingshighway Blvd, Campus Box 8131-MIR, St Louis, MO 63110.
    The adrenal glands in children can be affected by a variety of benign lesions. The diagnosis of adrenal lesions can be challenging, but assessment of morphologic changes in correlation with the clinical presentation can lead to an accurate diagnosis. These lesions can be classified by their cause: congenital (eg, discoid adrenal gland, horseshoe adrenal gland, and epithelial cysts), vascular and/or traumatic (eg, adrenal hemorrhage), infectious (eg, granulomatous diseases), enzyme deficiency disorders (eg, congenital adrenal hyperplasia [CAH] and Wolman disease), benign neoplasms (eg, pheochromocytomas, ganglioneuromas, adrenal adenomas, and myelolipomas), and adrenal mass mimics (eg, extralobar sequestration and extramedullary hematopoiesis). Read More

    A Case of Hemorrhagic Adrenal Pseudocyst Mimicking Solid Tumor.
    Am J Case Rep 2017 Sep 27;18:1034-1038. Epub 2017 Sep 27.
    Department of Urology, National Defense Medical College, Tokorozawa, Saitama, Japan.
    BACKGROUND Adrenal pseudocysts are often discovered incidentally on imaging, but the diagnosis and treatment can be challenging. A case of adrenal pseudocyst with hemorrhage is presented that mimicked a solid tumor on imaging, resulting in adrenalectomy. CASE REPORT A 78-year-old woman was found to have a right adrenal lesion on abdominal imaging. Read More

    Cerebral salt wasting syndrome in patients with minor head trauma - two case reports.
    Rom J Anaesth Intensive Care 2016 Oct;23(2):155-158
    Department of Anaesthesia and Intensive Care, Emergency County Hospital, Cluj-Napoca, Romania.
    We describe two polytrauma patients without severe head trauma who developed Cerebral Salt Wasting Syndrome (CSWS) during their stay in our ICU with natriuresis, hyponatremia and hypovolemia. Hyponatremia encountered in CSWS and the syndrome of inadequate antidiuretic hormone secretion (SIADH) is a common electrolyte finding in patients with severe head trauma, subarachnoid hemorrhage, malignancy and infections of the central nervous system. CSWS was an unexpected electrolyte finding in our patients with minor head trauma without neurological or neurosurgical problems. Read More

    Neonatal adrenal hemorrhage presenting as "Acute Scrotum"-looking beyond the obvious: a sonographic insight.
    J Ultrasound 2017 Sep 28;20(3):253-259. Epub 2017 Apr 28.
    Department of Radio-diagnosis, University College of Medical Sciences (University of Delhi) and GTB Hospital, Dilshad Garden, Delhi, 110095 India.
    Acute swelling and discoloration of scrotum in new born can have many localized causes like testicular torsion, inguinal hernia, scrotal or testicular edema, hydrocele, or even remote causes like adrenal hemorrhage. We report a neonate of adrenal hemorrhage presenting clinically as acute scrotum misguiding the clinician to rule out a local scrotal pathology. As the local clinical examination is not reliable in a newborn, it definitely requires an imaging evaluation to establish the diagnosis. Read More

    Spontaneous Adrenal Hematoma in a Pregnant Woman; a Case Report.
    Emerg (Tehran) 2017 24;5(1):e59. Epub 2017 Feb 24.
    Department of Anesthesiology, Imam Hosein Hospital, ShahidBeheshti University of Medical Sciences, Tehran, Iran.
    Spontaneous adrenal hematoma is a very rare condition and its prevalence has been reported to be about 1% in previous studies. Although various causes have been proposed to explain its incidence in existing case reports, the etiology and pathology of this condition is still not known. The present study presents a case of spontaneous adrenal hematoma in a pregnant 31 year old womanwithout history of trauma or other probable risk factors of hemorrhage, presenting to the emergency department with chief complaint of pain in the right flank. Read More

    Assessment of neonatal adrenal size using high resolution 2D ultrasound and its correlation with birth demographics and clinical outcomes.
    J Matern Fetal Neonatal Med 2017 Sep 24:1-7. Epub 2017 Sep 24.
    d Department of Pediatrics, Division of Neonatology , Case Western Reserve University, MetroHealth Medical Center , Cleveland , OH , USA.
    Objective: Assessment of adrenal function in a sick neonate remains a challenge in spite of major advances in neonatal care. We used 2D ultrasound of adrenal glands to assess maturity of adrenal glands in extremely preterm infants and sick term and near term infants.

    Study Design: We collected demographics details of 99 mother-infants pairs (24-41 weeks) and obtained 2D ultrasound scans of adrenal glands in first week of life to measure adrenal volume, fetal zone size, and adrenal to kidney ratios. Read More

    Management of primary aldosteronism in patients with adrenal hemorrhage following adrenal vein sampling: A brief review with illustrative cases.
    J Clin Hypertens (Greenwich) 2017 Dec 9;19(12):1372-1376. Epub 2017 Sep 9.
    Section on Endocrinology & Genetics (SEGEN), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), Bethesda, MD, USA.
    The authors describe the clinical investigation of two cases of primary aldosteronism with adrenal hemorrhage (AH) following adrenal vein sampling. A literature review was conducted regarding the medical management of primary aldosteronism in patients with AH following adrenal vein sampling. Guidelines on the management of primary aldosteronism with AH following adrenal vein sampling are lacking. Read More

    Organ- and cell-specific immune responses are associated with the outcomes of intracerebral hemorrhage.
    FASEB J 2018 Jan 6;32(1):220-229. Epub 2017 Sep 6.
    Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China;
    Severe brain injury significantly influences immune responses; however, the levels at which this influence occurs and which neurogenic pathways are involved are not well defined. Here, we used MRI to measure spleen volume and tissue diffusion changes in patients with intracerebral hemorrhage (ICH). We observed increased capillary exchange and spleen shrinkage by d 3 post-ICH, with recovery by d 14. Read More

    Management of Bleeding in Exclusive Endoscopic Ear Surgery: Pilot Clinical Experience.
    Otolaryngol Head Neck Surg 2017 Oct 5;157(4):700-706. Epub 2017 Sep 5.
    1 Department of Otorhinolaryngology-Head and Neck Surgery, University Hospital of Modena, Modena, Italy.
    Objective Transcanal exclusive endoscopic ear surgery requires the management of the endoscope and the surgical instruments in the external auditory canal. Bleeding in this narrow space is one of the most challenging issues, especially for novice endoscopic ear surgeons. We aim to assess the severity and occurrence of bleeding and describe strategies to control the bleeding during endoscopic ear surgery. Read More

    The radiographically diagnosed adrenal myelolipoma: what do we really know?
    Endocrine 2017 Nov 2;58(2):289-294. Epub 2017 Sep 2.
    Departments of Surgery and Radiology, University of California, Davis Medical Center, Sacramento, CA, USA.
    Purpose: Adrenal myelolipomas are uncommon, benign tumors of the adrenal glands that are not routinely evaluated for autonomous hormone secretion or followed by repeat imaging, but may lead to retroperitoneal hemorrhage. Little is known about the natural history these tumors with the majority of previous publications being confined to case reports and small case series.

    Methods: We reviewed the computed tomography (CT) reports of 62,279 patients evaluated at a tertiary referral center between 2002 and 2015 for the presence of an adrenal myelolipoma >1 cm in size. Read More

    Inducing heat shock protein 70 expression provides a robust antithrombotic effect with minimal bleeding risk.
    Thromb Haemost 2017 Aug 27;117(9):1722-1729. Epub 2017 Jul 27.
    José Hermida, MD,PhD, University of Navarra, Center for Applied Medical Research (CIMA), Laboratory of Thrombosis and Haemostasis, Pío XII 55, Pamplona 31008, Spain, Tel.: +34948194700×3027, Fax: +34948194716, E-mail:
    Antithrombotic medications target coagulation factors. Their use is associated with an increased bleeding risk. Safer drugs are needed. Read More

    Acute hypopituitarism associated with periorbital swelling and cardiac dysfunction in a patient with pituitary tumor apoplexy: a case report.
    J Med Case Rep 2017 Aug 24;11(1):235. Epub 2017 Aug 24.
    Department of Respiratory Medicine, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Niigata, Japan.
    Background: Pituitary tumor apoplexy is a rare clinical syndrome caused by acute hemorrhage or infarction in a preexisting pituitary adenoma. It typically manifests as an acute episode of headache, visual disturbance, mental status changes, cranial nerve palsy, and endocrine pituitary dysfunction. However, not all patients present with classical symptoms, so it is pertinent to appreciate the clinical spectrum of pituitary tumor apoplexy presentation. Read More

    Nontraumatic adrenal hemorrhage: the adrenal stress.
    Radiol Case Rep 2017 Sep 15;12(3):483-487. Epub 2017 Apr 15.
    Radiology Department, San Carlo Hospital, Potito Petrone St, 85100 Potenza, Italy.
    Bilateral adrenal hemorrhage is a rare condition, which is burdened by potentially life-threatening consequences related to the development of acute adrenal insufficiency. Despite treatment with stress-dose glucocorticoids, a mortality rate of 15% has been reported, which varies according to the severity of underlying predisposing illness and could be much more higher if the adrenal insufficiency is not promptly recognized. An early diagnosis is crucial, though, because of nonspecific clinical and laboratory findings, adrenal hemorrhage is rarely suspected. Read More

    [Fortuitous discovery of an adrenal mass following spontaneous retroperitoneal hemorrhage].
    Rev Med Liege 2017 Jul;72(7-8):358-362
    Service de Chirurgie Digestive, CH Bois de l'Abbaye, Seraing, Belgique.
    We report a case of spontaneous retroperitoneal haemorrhage by bleeding of an adrenal adenoma. Retroperitoneal haemorrhages are rarely encountered in practice, but must be rapidly diagnosed due to the life threatening risk. The etiologies, clinical assessment, management and differential diagnosis of spontaneous retroperitoneal haemorrhages are discussed. Read More

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