2,147 results match your criteria Adrenal Carcinoma Imaging


Adrenocortical carcinoma: presentation and outcome of a contemporary patient series.

Endocrine 2019 Apr 12. Epub 2019 Apr 12.

Endocrinology, Abdominal Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.

Background: Adrenocortical carcinoma (ACC) is a rare endocrine carcinoma with poor 5-year survival rates of < 40%. According to the literature, ACC is rarely an incidental imaging finding. However, presentation, treatment and outcome may differ in modern series. Read More

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http://dx.doi.org/10.1007/s12020-019-01918-9DOI Listing

Double trouble: two cases of dual adrenal pathologies in one adrenal mass.

Endocrinol Diabetes Metab Case Rep 2019 Mar 23;2019. Epub 2019 Mar 23.

St. Vincent's University Hospital and University College Dublin, Dublin, Ireland.

Context Adrenal incidentalomas (AI) represent an increasingly common problem in modern endocrine practice. The diagnostic approach to AIs can be challenging and occasionally reveals surprising features. Here we describe two rare cases of complex adrenal lesions consisting of phaeochromocytomas with synchronous metastases from extra-adrenal primaries. Read More

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http://dx.doi.org/10.1530/EDM-18-0151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6432979PMC
March 2019
1 Read

Spectral CT and its specific values in the staging of patients with non-small cell lung cancer: technical possibilities and clinical impact.

Clin Radiol 2019 Mar 21. Epub 2019 Mar 21.

Department of Radiology, Charité University Medicine Berlin, Campus Virchow Klinikum, Berlin, Germany; Department of Radiology, University Hospital Munich, Ludwig-Maximilians University (LMU), Munich, Germany. Electronic address:

Aim: To investigate how spectral computed tomography (SCT) values impact the staging of non-small cell lung cancer (NSCLC) patients.

Materials And Methods: One hundred and thirteen patients with confirmed NSCLC were included in a prospective cohort study. All patients underwent single-phase contrast-enhanced SCT (using the fast tube voltage switching technique, 80-140 kV). Read More

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http://dx.doi.org/10.1016/j.crad.2019.02.010DOI Listing
March 2019
1 Read

LARGE ADRENAL INCIDENTALOMAS REQUIRE A DEDICATED DIAGNOSTIC PROCEDURE.

Endocr Pract 2019 Mar 13. Epub 2019 Mar 13.

From : Aix Marseille Université, Assistance Publique Hôpitaux de Marseille, Marseille, France.

Introduction: The management of large non secreting adrenal tumors (at least 4 cm) is still a matter of debate as it is unclear whether imaging, especially 18F-FDG, can be used to characterize their potential malignancy. Moreover, the risk of new hypersecretion in non-operated tumors is uncertain. Our aim was to better characterize these large adrenal incidentalomas. Read More

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http://dx.doi.org/10.4158/EP-2018-0616DOI Listing
March 2019
2 Reads

Screening in adrenal tumors.

Curr Opin Oncol 2019 May;31(3):243-246

Department of Medicine, Division of Endocrinology.

Purpose Of Review: Adrenal tumors are mostly encountered as incidentalomas in patients undergoing imaging not performed for suspected adrenal disease; although the majority are benign and nonfunctioning, malignant tumors and functioning tumors need to be excluded. The purpose of this review is to highlight recent advances in the evaluation of adrenal tumors.

Recent Findings: As a consequence of increased use of technologically improved imaging techniques, the detection of adrenal incidentalomas has continued to increase. Read More

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http://dx.doi.org/10.1097/CCO.0000000000000528DOI Listing
May 2019
2 Reads

Multiple endocrine neoplasia type 2A syndrome (MEN2A) and usefulness of 68Ga-DOTATATE PET/CT in this syndrome.

Ann Ital Chir 2019 Mar 4;8. Epub 2019 Mar 4.

Aim: The aim of this study was to evaluate a new imaging method 68Ga-DOTATATE PET/CT as an alternative method to diagnose evidence of neuroendocrine tumors or their metastasis (if any) in patient with MEN 2A.

Methods: Three patients( 2F, 1M; age 28,46 and 50 years) with MEN 2A syndrome who underwent 68Ga-DOTATATE PET/CT scan were prospectively evaluated. PET/CT images were analyzed with measurement of maximum standardized uptake value (SUVmax). Read More

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March 2019
5 Reads
0.683 Impact Factor

A unique case of ectopic Cushing's syndrome from a thymic neuroendocrine carcinoma.

Endocrinol Diabetes Metab Case Rep 2019 Feb 22;2019. Epub 2019 Feb 22.

Departments of Endocrinology, Diabetes & Metabolism, Cleveland Clinic, Cleveland, Ohio, USA.

Ectopic adrenocorticotropic hormone (ACTH) production leading to ectopic ACTH syndrome accounts for a small proportion of all Cushing's syndrome (CS) cases. Thymic neuroendocrine tumors are rare neoplasms that may secrete ACTH leading to rapid development of hypercortisolism causing electrolyte and metabolic abnormalities, uncontrolled hypertension and an increased risk for opportunistic infections. We present a unique case of a patient who presented with a mediastinal mass, revealed to be an ACTH-secreting thymic neuroendocrine tumor (NET) causing ectopic CS. Read More

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http://dx.doi.org/10.1530/EDM-19-0002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391898PMC
February 2019
1 Read

Frequency and imaging features of abdominal immune-related adverse events in metastatic lung cancer patients treated with PD-1 inhibitor.

Abdom Radiol (NY) 2019 Feb 21. Epub 2019 Feb 21.

Department of Medical Oncology and Department of Medicine, Dana Farber Cancer Institute, Harvard Medical School, 450 Brookline Avenue, Boston, MA, 02215, USA.

Purpose: To investigate the frequency and imaging features of radiographically evident abdominal immune-related adverse events (irAEs) in patients with metastatic non-small-cell lung cancer (NSCLC) treated with PD-1 inhibitors.

Methods: This retrospective study included 137 patients with metastatic NSCLC treated with PD-1 inhibitor nivolumab monotherapy (75 women; median age: 65 years), who had a baseline CT and at least one follow-up abdomen CT during therapy. Baseline and all follow-up abdominal CTs performed for monitoring of nivolumab therapy were reviewed to identify the organ-specific abdominal irAEs including colitis/enteritis, hepatitis, biliary toxicity, pancreatitis, nephritis, sarcoid-like reaction, and pancreatic and adrenal atrophy. Read More

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http://dx.doi.org/10.1007/s00261-019-01935-2DOI Listing
February 2019

Small Cell Lung Cancer with Pituitary Metastasis Presenting as Secondary Adrenal Insufficiency: A Case Report and Literature Review.

Am J Case Rep 2019 Feb 17;20:207-211. Epub 2019 Feb 17.

Department of Endocrinology, University of California San Francisco, San Francisco, CA, USA.

BACKGROUND Pituitary gland metastasis is rarely the initial presentation of metastatic cancer. Most cases of pituitary gland metastasis are asymptomatic with diabetes insipidus being the most common symptomatic presentation. It can rarely present with symptoms of hormone underproduction such as secondary adrenal insufficiency. Read More

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http://dx.doi.org/10.12659/AJCR.913388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388645PMC
February 2019
2 Reads

A Rare Presentation of Colorectal Cancer with Unusual Progressive Intramuscular and Subcutaneous Metastatic Spread.

Asia Ocean J Nucl Med Biol 2019 ;7(1):89-94

Tabriz University of Medical Sciences, Tabriz, Iran.

Colorectal carcinoma is one of the most common causes of cancer-related death, worldwide. Recently, due to the introduction of novel imaging and therapeutic techniques, five-year survival of patients has increased. However, distant metastasis is still expected in half of the patients. Read More

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http://dx.doi.org/10.22038/AOJNMB.2018.11934DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352049PMC
January 2019
3 Reads

Synchronous renal cell carcinoma and pheochromocytoma presenting as acute decompensated heart failure.

J Postgrad Med 2019 Jan-Mar;65(1):44-46

Division of Cardiology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.

We report a 49-year-old woman who presented with a hypertensive crisis and acute heart failure and reduced left ventricular systolic function. An abdominal ultrasonography revealed a huge lobulated heterogeneous mass at the lower pole of the right kidney and a mass over the left suprarenal area, which were further delineated by magnetic resonance imaging. The patient underwent laparoscopic right radical nephrectomy and left adrenalectomy. Read More

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http://www.jpgmonline.com/text.asp?2019/65/1/44/250961
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http://dx.doi.org/10.4103/jpgm.JPGM_701_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380140PMC
January 2019
6 Reads

Renal and adrenal masses containing fat at MRI: Proposed nomenclature by the society of abdominal radiology disease-focused panel on renal cell carcinoma.

J Magn Reson Imaging 2019 Apr 28;49(4):917-926. Epub 2019 Jan 28.

Department of Radiology, Brigham and Women's Hospital, Boston, Massachusetts, USA.

This article proposes a consensus nomenclature for fat-containing renal and adrenal masses at MRI to reduce variability, improve understanding, and enhance communication when describing imaging findings. The MRI appearance of "macroscopic fat" occurs due to a sufficient number of aggregated adipocytes and results in one or more of: 1) intratumoral signal intensity (SI) loss using fat-suppression techniques, or 2) chemical shift artifact of the second kind causing linear or curvilinear India-ink (etching) artifact within or at the periphery of a mass at macroscopic fat-water interfaces. "Macroscopic fat" is most commonly observed in adrenal myelolipoma and renal angiomyolipoma (AML) and only rarely encountered in other adrenal cortical tumors and renal cell carcinomas (RCC). Read More

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http://dx.doi.org/10.1002/jmri.26542DOI Listing
April 2019
3 Reads

Biomolecular engineering of antidehydroepiandrosterone antibodies: a new perspective in cancer diagnosis and treatment using single-chain antibody variable fragment.

Nanomedicine (Lond) 2019 Mar 29;14(6):689-705. Epub 2019 Jan 29.

Pós-graduação em Engenharia de Bioprocessos e Biotecnologia, Curitiba, Brazil.

Aim: To develop a monoclonal antibody against dehydroepiandrosterone (DHEA) and miniaturize it, generating a single-chain antibody variable fragment (scFv) against DHEA as an adrenocortical carcinoma (ACC) marker.

Material & Methods: DHEA conjugated to keyhole limpet hemocyanin was used as an immunogen to obtain anti-DHEA hybridomas. Variable fragments were cloned from hybridoma 5B7 total RNA, and used to detect DHEA in normal adrenal tissue and ACC cells. Read More

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http://dx.doi.org/10.2217/nnm-2018-0230DOI Listing
March 2019
4 Reads

A rare case of pure testosterone-secreting adrenal adenoma in a postmenopausal elderly woman.

BMC Endocr Disord 2019 Jan 23;19(1):14. Epub 2019 Jan 23.

Department of Endocrinology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Zhejiang, 310003, Hangzhou, China.

Background: Hyperandrogenemia is more common in puberty and reproductive age, but relatively rare in postmenopausal women. Postmenopausal virilization may result from androgen-producing tumors. Androgen-secreting adrenal tumors are rare in clinical practice and are diagnosed as adrenocortical carcinoma, most of which can co-secrete androgen and cortisol. Read More

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http://dx.doi.org/10.1186/s12902-019-0342-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343319PMC
January 2019
2 Reads

Seminal vesicle metastasis after liver transplantation for hepatocellular carcinoma: A case report.

Medicine (Baltimore) 2019 Jan;98(3):e13770

Department of Gastroenterology, The Affiliated Drum Tower Hospital of Nanjing University, Medical School.

Rationale: Cancer recurrence and metastasis after liver transplantation (LT) is common in some hepatocellular carcinoma (HCC) patients. The most common sites of extrahepatic metastases are lung, regional lymph node, adrenal gland, and bone. To our knowledge, HCC metastasis to the seminal vesicle after LT has not been reported in the literature. Read More

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http://dx.doi.org/10.1097/MD.0000000000013770DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370123PMC
January 2019
4 Reads

[Clinical value of transcatheter arterial chemoembolization therapy for hepatocellular carcinoma with blood supply from right adrenal artery].

Zhonghua Gan Zang Bing Za Zhi 2018 Nov;26(11):835-841

Department of Radiology, the Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.

To study the clinical value of transcatheter arterial chemoembolization (TACE) therapy for hepatocellular carcinoma with blood supply from right adrenal artery. An imaging and clinical data of HCC patients with blood supply from right adrenal artery were collected from 2012 to 2016 after TACE treatment in the Second Affiliated Hospital of Chongqing Medical University and the safety and therapeutic efficacy of complete embolization therapy was analyzed retrospectively. Twenty hepatocellular carcinoma patients with blood supply from right adrenal artery had received 23 times treatment. Read More

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http://dx.doi.org/10.3760/cma.j.issn.1007-3418.2018.11.006DOI Listing
November 2018
8 Reads

Cyclic Cushing's syndrome caused by neuroendocrine tumor: a case report.

Endocr J 2019 Feb 19;66(2):175-180. Epub 2018 Dec 19.

Department of Endocrinology, Qilu Hospital of Shandong University, Jinan 250012, China.

Cushing's syndrome (CS) is a clinical syndrome characterized by hypercortisolemia. Cyclic Cushing's syndrome (CCS), which exhibits a periodic or irregular increasing pattern in cortisol, is a rare type of Cushing's syndrome. A 37-year-old man came to our hospital because of repeated dizzy spells, weakness and hypercortisolemia lasting two weeks. Read More

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http://dx.doi.org/10.1507/endocrj.EJ18-0168DOI Listing
February 2019
20 Reads

Bilateral renal cell carcinoma with bilateral adrenal metastasis: a therapeutic challenge.

BMJ Case Rep 2018 Dec 13;11(1). Epub 2018 Dec 13.

Urology, King George's Medical University, Lucknow, India.

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http://dx.doi.org/10.1136/bcr-2018-227176DOI Listing
December 2018
2 Reads

Management of Older Patients With Metastatic Renal Cell Carcinoma Receiving Sunitinib: A Hypothetical, Illustrative Case Scenario.

J Adv Pract Oncol 2018 Jan-Feb;9(1):67-76. Epub 2018 Jan 1.

Duke Prostate Center, Durham, North Carolina.

Tom, a 75-year-old white male, was recently diagnosed with metastatic renal cell carcinoma (RCC; Tom's case is not an actual clinical case but has been developed by the authors as an exemplar). Two years prior, he had undergone a left partial (laparoscopic) nephrectomy for clear cell RCC. At that time, he had a stage 3 disease (the tumor extended into perinephric tissues but not into the ipsilateral adrenal gland and not beyond Gerota's fascia [Cancer. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296420PMC
January 2018
3 Reads

RNA-Sequencing Analysis of Adrenocortical Carcinoma, Pheochromocytoma and Paraganglioma from a Pan-Cancer Perspective.

Cancers (Basel) 2018 Dec 15;10(12). Epub 2018 Dec 15.

Section on Medical Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, 10 Center Drive, Building 10, Room 1E-3140, Bethesda, MD 20892, USA.

Adrenocortical carcinoma (ACC) and pheochromocytoma and paraganglioma (PPGL) are defined by clinicopathological criteria and can be further sub-divided based on different molecular features. Whether differences between these molecular subgroups are significant enough to re-challenge their current clinicopathological classification is currently unknown. It is also not fully understood to which other cancers ACC and PPGL show similarity to. Read More

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http://dx.doi.org/10.3390/cancers10120518DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315481PMC
December 2018
5 Reads

Perforation of small intestine secondary to metastatic lung adenocarcinoma: A case report.

Medicine (Baltimore) 2018 Dec;97(49):e13469

Department of Emergency Surgery, Union Hospital.

Rationale: About 50% of patients with a diagnosis of nonsmall cell lung carcinoma exhibit metastatic disease at the time of diagnosis. The preferential sites of extrapulmonary spread are the lymph nodes, liver, brain, adrenal glands, and bones; gastrointestinal tract perforation secondary to metastatic lung cancer is extremely rare.

Patient Concerns: A 60-year-old male nonsmoker patient presented with a 20-day history of facial, neck, and right upper limb edema. Read More

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http://dx.doi.org/10.1097/MD.0000000000013469DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310494PMC
December 2018

[A Case of Renal Cell Carcinoma withIpsilateral Renal Pelvic Metastasis Mimicking Double Cancer].

Hinyokika Kiyo 2018 Nov;64(11):439-443

The Department of Urology, Rakuwakai Otowa Hospital.

A 71-year-old man with left flank pain was referred to our hospital. Computed tomography (CT) revealed a left renal tumor, left renal pelvic wall thickening, bilateral adrenal gland swelling, multiple pulmonary nodules, and a bone metastatic tumor. Further, positron emission tomography/CT revealed increased 18F fluorodeoxyglucose uptake in the left renal tumor, multiple pulmonary nodules, and bone metastatic tumor. Read More

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http://dx.doi.org/10.14989/ActaUrolJap_64_11_439DOI Listing
November 2018

[A Case Report : FDG Uptake to Brown Adipose Tissue Activated by Elevated Serum Catecholamine in a Patient with Pheochromocytoma].

Hinyokika Kiyo 2018 Nov;64(11):435-438

The Department of Urology, Osaka National Hospital.

A 69-year-old woman was admitted to the previous hospital because of a right adrenal tumor detected by a medical checkup. Although the tumor was diagnosed as non-functional adrenal adenoma, abdominal computed tomography (CT) revealed a left renal mass which was suspected to be renal cell carcinoma. Chest CT seeking for metastatic lesions revealed lung cancer of the left lung. Read More

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http://dx.doi.org/10.14989/ActaUrolJap_64_11_435DOI Listing
November 2018
2 Reads

Primary malignant tumors of the adrenal glands.

Clinics (Sao Paulo) 2018 12 10;73(suppl 1):e756s. Epub 2018 Dec 10.

Unidade de Suprarrenal, Laboratorio de Hormonios e Genetica Molecular LIM/42, Servico de Endocrinologia e Metabologia, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR.

Malignancy must be considered in the management of adrenal lesions, including those incidentally identified on imaging studies. Adrenocortical carcinomas (ACCs) are rare tumors with an estimated annual incidence of 0.7-2 cases per year and a worldwide prevalence of 4-12 cases per million/year. Read More

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http://dx.doi.org/10.6061/clinics/2018/e756sDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257058PMC
December 2018
1 Read

[Leiomyosarcoma of the adrenal gland - two cases report].

Pol Merkur Lekarski 2018 Nov;45(269):189-191

Maria Skłodowska-Curie Institute - Oncology Center of Warsaw, Poland: Department of Soft Tissue/Bone Sarcoma and Melanoma.

Primary adrenal leiomyosarcomas are very rare adrenal mesenchymal tumours, only few dozen has been reported in the English language literature so far. We present two cases of patients with primary adrenal leiomyoosarcomas. 80 year-old female admitted with left adrenal tumour with presumptive diagnosis of nonadenoma, laparoscopic adrenalectomy was performed and 85 year-old man who underwent surgical resection by laparotomy of adrenal tumour suspected for adrenal carcinoma. Read More

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November 2018
2 Reads

The coexistence of Cushing syndrome and gynecomastia as the manifestations of adrenocortical carcinoma.

Kaohsiung J Med Sci 2018 12 4;34(12):705-706. Epub 2018 Jul 4.

Division of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; Excellence Center in Diabetes, Hormones and Metabolism, King Chulalongkorn Memorial Hospital, Bangkok, Thailand. Electronic address:

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http://dx.doi.org/10.1016/j.kjms.2018.06.004DOI Listing
December 2018
2 Reads
0.805 Impact Factor

Ewing's sarcoma of kidney in a 60-year-old patient with local recurrence: A rare occurrence.

J Cancer Res Ther 2018 Oct-Dec;14(6):1422-1424

Department of Medical Oncology, Gazi University Faculty of Medicine, Ankara, Turkey.

Ewing's family of tumors is aggressive tumors and frequently arises from bone and soft tissue. They might also arise from nonosseous structures such as gastrointestinal tract, adrenal glands, or kidney. Primary renal Ewing's sarcoma (ES)/primitive neuroectodermal tumor is an extremely rare entity which has aggressive clinical course. Read More

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http://dx.doi.org/10.4103/0973-1482.191062DOI Listing
February 2019
2 Reads

Plasma steroid metabolome profiling for the diagnosis of adrenocortical carcinoma.

Eur J Endocrinol 2019 Feb;180(2):117-125

Division of Endocrinology/Diabetology and Core Unit Clinical Mass Spectrometry, Department of Internal Medicine I, University Hospital Würzburg.

Objective Current workup for the pre-operative distinction between frequent adrenocortical adenomas (ACAs) and rare but aggressive adrenocortical carcinomas (ACCs) combines imaging and biochemical testing. We here investigated the potential of plasma steroid hormone profiling by liquid chromatography tandem mass spectrometry (LC-MS/MS) for the diagnosis of malignancy in adrenocortical tumors. Design Retrospective cohort study of prospectively collected EDTA-plasma samples in a single tertiary reference center. Read More

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http://dx.doi.org/10.1530/EJE-18-0782DOI Listing
February 2019
2 Reads

[French ccAFU guidelines - Update 2018-2020: Adrenal cancer].

Prog Urol 2018 Nov 27;28(12S):S175-S193. Epub 2018 Oct 27.

Service d'urologie, hôpital d'instruction des armées Sainte-Anne, BP 600, 83800 Toulon cedex 09, France; Service d'urologie, hôpital européen Georges-Pompidou, université Paris Descartes, AP-HP, 75015 Paris, France. Electronic address:

Objective: To update French oncology guidelines concerning adrenal cancer.

Methods: Comprehensive Medline search between 2016 and 2018 upon diagnosis, treatment and follow-up of adrenal cancer to update 2013 guidelines. Level of evidence was evaluated according to AGREE-II. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S11667087183051
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http://dx.doi.org/10.1016/j.purol.2018.08.015DOI Listing
November 2018
20 Reads

Patterns of Lymph Node Recurrence in Adrenocortical Carcinoma: Possible Implications for Primary Surgical Treatment.

Ann Surg Oncol 2019 Feb 15;26(2):531-538. Epub 2018 Nov 15.

Department of General, Viszeral, and Thoracic Surgery, Kreisklinik Altötting, Altötting, Germany.

Background: In the surgical treatment of adrenocortical carcinoma (ACC), lymphadenectomy may improve oncologic outcome. However, patterns of metastatic lymphatic spread in ACC are unknown.

Methods: Clinical data of patients included in the European Network for the Study of Adrenal Tumors (ENSAT) registry were retrospectively reviewed. Read More

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http://link.springer.com/10.1245/s10434-018-6999-z
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http://dx.doi.org/10.1245/s10434-018-6999-zDOI Listing
February 2019
14 Reads

An Unusual Case of Papillary Thyroid Carcinoma Iodine-131 Avid Metastasis to the Adrenal Gland.

Acta Clin Croat 2018 Jun;57(2):372-376

Department of Oncology and Nuclear medicine, Sestre milosrdnice University Hospital Center, Zagreb, Croatia.

Papillary thyroid carcinoma (PTC) is considered one of the most favorable tumors, indolent, with rare distant dissemination. Lungs and bones are the most common metastatic sites. Unusual sites of PTC distant metastases are extremely rare. Read More

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https://hrcak.srce.hr/index.php?show=clanak&id_clanak_je
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http://dx.doi.org/10.20471/acc.2018.57.02.20DOI Listing
June 2018
20 Reads

CT diagnosis for metastasis of clear cell renal cell carcinoma to the pancreas: Three case reports.

Medicine (Baltimore) 2018 Nov;97(46):e13200

Department of Radiology, Jinshan TCM-Integrated Hospital of Shanghai City, Shanghai.

Rationale: Clear cell renal cell carcinoma (CCRCC) metastasis to pancreas is clinically rare. Misdiagnosis for these cases is frequently due to the low incidence, lack of specific clinical symptoms, and laboratory results.

Patient Concerns: Three female patients aged 47 years, 69 years, and 76 years, respectively, were admitted to hospital for routine examination after resection of clear cell carcinoma of kidney for 69 months, 57 months, and 123 months, respectively. Read More

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http://dx.doi.org/10.1097/MD.0000000000013200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257552PMC
November 2018
20 Reads

Natural killer/T-cell lymphoma with concomitant syndrome of inappropriate antidiuretic hormone secretion: A case report and review of literature.

World J Clin Cases 2018 Nov;6(13):694-702

Department of Respiratory Medicine, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning Province, China.

We report a case of natural killer (NK)/T-cell lymphoma with concomitant syndrome of inappropriate antidiuretic hormone secretion (SIADH). The patient was a 64-year-old woman with a history of nasopharyngeal carcinoma of over 30 years. She was admitted with a chief complaint of intermittent fever for 2 mo. Read More

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http://dx.doi.org/10.12998/wjcc.v6.i13.694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232570PMC
November 2018
7 Reads

Spontaneous regression of adrenal metastasis from renal cell carcinoma after sunitinib withdrawal: case report and literature review.

BMC Urol 2018 Nov 14;18(1):105. Epub 2018 Nov 14.

Department of Urology, Mackay Memorial Hospital, Taipei, Taiwan.

Background: The spontaneous regression of metastatic renal cell carcinoma is a rare phenomenon, with an estimated incidence of < 1%. We report a case of post-nephrectomy renal cell carcinoma adrenal metastasis, followed by the spontaneous regression of the metastasis after withdrawal of sunitinib.

Case Presentation: The patient was a 55-year-old male with clear cell type renal cell carcinoma who previously underwent a left laparoscopic radical nephrectomy. Read More

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https://bmcurol.biomedcentral.com/articles/10.1186/s12894-01
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http://dx.doi.org/10.1186/s12894-018-0420-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236987PMC
November 2018
16 Reads

Treatment of Refractory Adrenocortical Carcinoma with Thalidomide: Analysis of 27 Patients from the European Network for the Study of Adrenal Tumours Registry.

Exp Clin Endocrinol Diabetes 2018 Nov 14. Epub 2018 Nov 14.

Department of Internal Medicine I, Endocrine and Diabetes Unit, University Hospital Würzburg, University of Würzburg, Germany.

Objective: Adrenocortical carcinoma (ACC) is a rare malignancy with a dismal prognosis. In advanced stages, tumour control by mitotane and cytotoxic chemotherapy is often temporary and salvage treatments are warranted.

Methods: Retrospective cohort study of participants in the prospective European Networks for the Study of Adrenal Tumours (ENSAT) registry. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/a-0747-5571
Publisher Site
http://dx.doi.org/10.1055/a-0747-5571DOI Listing
November 2018
20 Reads

First Reported Case of Endoscopic Ultrasound-Guided Core Biopsy Yielding Diagnosis of Primary Adrenal Leiomyosarcoma.

Case Rep Gastrointest Med 2018 3;2018:8196051. Epub 2018 Oct 3.

Division of Gastroenterology and Hepatology, University of Florida and Malcom Randall VA Medical Center, Gainesville, FL, USA.

Primary adrenal leiomyosarcoma (PAL) is an extremely rare mesenchymal tumor with only a few isolated case reports in the medical literature. Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) or endoscopic ultrasound-guided core biopsy (EUS-CB) is a safe, effective modality for sampling lesions in the gastrointestinal tract and adjacent organs, including the adrenal glands. We describe the case of a 50-year-old male presenting with abdominal pain and unintentional weight loss over the course of one year. Read More

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https://www.hindawi.com/journals/crigm/2018/8196051/
Publisher Site
http://dx.doi.org/10.1155/2018/8196051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192140PMC
October 2018
19 Reads

Adrenal Oncocytoma: An Incidental Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Findings with Magnetic Resonance Imaging Correlation.

Indian J Nucl Med 2018 Oct-Dec;33(4):345-347

Department of Radiology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.

A good percentage of adrenal masses in patients with known malignancy may be benign; thus, noninvasive characterization is important in preventing unnecessary biopsy. This case report represents a patient with papillary thyroid carcinoma and known lung metastasis for which she was followed up with whole-body fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) postradioactive iodine therapy. During the follow-up, she had developed an adrenal mass lesion seen by FDG PET/CT and further characterized by magnetic resonance imaging (MRI). Read More

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http://www.ijnm.in/text.asp?2018/33/4/345/242945
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http://dx.doi.org/10.4103/ijnm.IJNM_78_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194757PMC
November 2018
3 Reads

Predictive factors for adrenal metastasis in extra-adrenal malignancy patients with solitary adrenal mass.

J Surg Oncol 2018 Dec 27;118(8):1271-1276. Epub 2018 Oct 27.

Department of Urology, School of Medicine, Kyungpook National University, Daegu, Korea.

Background And Objectives: The adrenal gland is a frequent site for metastasis, and a solitary adrenal mass is often observed during staging workup or imaging follow-up in patients with extra-adrenal malignancy. To create an appropriate management plan, it is essential to distinguish between benign adrenal lesions and metastasis in patients with extra-adrenal cancer having solitary adrenal masses. Therefore, here we evaluated the predictive factors for adrenal metastasis in patients with extra-adrenal malignancy having solitary adrenal mass. Read More

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http://doi.wiley.com/10.1002/jso.25272
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http://dx.doi.org/10.1002/jso.25272DOI Listing
December 2018
19 Reads

An Interesting Case of Hepatic Adrenocortical Carcinoma.

Acta Med Indones 2018 Jul;50(3):257-259

Department of Internal Medicine, Faculty of Medicine Universitas Padjadjaran - Hasan Sadikin Hospital, Bandung, Indonesia.

Adrenocortical carcinoma (ACC) is a rare solid tumor with an incidence of 0.5 to 2 cases per million per year. It affects women more commonly than men with a ratio of 1. Read More

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July 2018
13 Reads

CT and MRI of adrenal gland pathologies.

Quant Imaging Med Surg 2018 Sep;8(8):853-875

Department of Radiology, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, China.

Besides ultrasound and nuclear medicine techniques, computed tomography (CT) and magnetic resonance imaging (MRI) are commonly used to examine adrenal lesions in both symptomatic and asymptomatic patients. Some adrenal lesions have characteristic radiological features. If an adrenal nodule is discovered incidentally, determining whether the lesion is benign or malignant is of great importance. Read More

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http://qims.amegroups.com/article/view/21428/21140
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http://dx.doi.org/10.21037/qims.2018.09.13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177362PMC
September 2018
23 Reads

European Society of Endocrinology Clinical Practice Guidelines on the management of adrenocortical carcinoma in adults, in collaboration with the European Network for the Study of Adrenal Tumors

Eur J Endocrinol 2018 10 1;179(4):G1-G46. Epub 2018 Oct 1.

Department of Clinical and Biological Sciences, Internal Medicine, San Luigi Hospital, University of Turin, Orbassano, Italy

Adrenocortical carcinoma (ACC) is a rare and in most cases steroid hormone-producing tumor with variable prognosis. The purpose of these guidelines is to provide clinicians with best possible evidence-based recommendations for clinical management of patients with ACC based on the GRADE (Grading of Recommendations Assessment, Development and Evaluation) system. We predefined four main clinical questions, which we judged as particularly important for the management of ACC patients and performed systematic literature searches: (A) What is needed to diagnose an ACC by histopathology? (B) Which are the best prognostic markers in ACC? (C) Is adjuvant therapy able to prevent recurrent disease or reduce mortality after radical resection? (D) What is the best treatment option for macroscopically incompletely resected, recurrent or metastatic disease? Other relevant questions were discussed within the group. Read More

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https://eje.bioscientifica.com/view/journals/eje/179/4/EJE-1
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http://dx.doi.org/10.1530/EJE-18-0608DOI Listing
October 2018
3 Reads

A case report of late local relapse of adrenocortical carcinoma 18 years after adrenalectomy.

Exp Oncol 2018 Oct;40(3):251-253

O.O. Bogomolets National Medical University, Kyiv 01601, Ukraine.

Adrenocortical cancer is an extremely rare tumor presenting with extensive locoregional spread at the time of diagnosis. Due to the diagnostic difficulties preoperatively and a lack of effective treatment options, patients have poor prognosis. Patients succumb to metastases within a couple of months. Read More

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October 2018
11 Reads

Oncocytic neoplasms; rare adrenocortical tumours - a report of eleven patients.

Endokrynol Pol 2018 27;69(6):682-687. Epub 2018 Sep 27.

Department of Internal Medicine, Division of Endocrinology and Metabolism, Kastamonu State Hospital, Kastamonu, Turkey.

Introduction: Oncocytomas of adrenal glands are extremely rare and usually present as incidentally detected masses. We aimed to present a series of patients with adrenal oncocytomas and review the literature.

Material And Methods: Electronic database of patients with adrenal tumours, who were admitted to the internal medicine and endocrinology and metabolism outpatient clinics of Uludag University Medical Faculty between January 2005 and November 2016, were assessed retrospectively. Read More

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http://dx.doi.org/10.5603/EP.a2018.0066DOI Listing
April 2019
3 Reads

Evaluation, Staging, and Surgical Management for Adrenocortical Carcinoma: An Update from the SSO Endocrine and Head and Neck Disease Site Working Group.

Ann Surg Oncol 2018 Nov 18;25(12):3460-3468. Epub 2018 Sep 18.

Division of Surgical Oncology and Endocrine Surgery, Vanderbilt University, Nashville, TN, USA.

This is the first of a two-part review on adrenocortical carcinoma (ACC), a rare and aggressive malignancy that often presents at an advanced stage. Most patients present with symptoms related to cortisol and/or androgen excess. Appropriate biochemical evaluation and imaging is important in assessing the extent of disease, operative planning, and oncologic surveillance for patients with ACC. Read More

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http://dx.doi.org/10.1245/s10434-018-6749-2DOI Listing
November 2018
4 Reads

[Polymetastatic highly aggressive Small Cell Undifferentiated Neuroendocrine Carcinoma of Ascending Colon].

Cir Cir 2018 ;86(5):446-449

Fourth Surgical Department. Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.

Neuroendocrine carcinoma (NEC) of the colon is a rare and very aggressive tumor with poor prognosis. The current case report presents a 53-year-old male with a 6 cm × 10 cm ascending colon carcinoma, causing large intestine obstruction, with simultaneous multiple hepatic metastases and peritoneal carcinomatosis. Surgical resection of the primary tumor was performed, because of the bowel obstruction, to ameliorate the symptoms before the onset of chemotherapy. Read More

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http://dx.doi.org/10.24875/CIRU.18000058DOI Listing
February 2019
4 Reads
0.322 Impact Factor

Clinical, Biochemical, and Radiological Characteristics of a Single-Center Retrospective Cohort of 705 Large Adrenal Tumors.

Mayo Clin Proc Innov Qual Outcomes 2018 Mar 21;2(1):30-39. Epub 2017 Dec 21.

Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic, Rochester, MN.

Objective: To characterize large adrenal tumors (≥4 cm in diameter) and to identify features associated with malignancy.

Patients And Methods: We investigated the clinical, biochemical, and imaging characteristics in a large retrospective single-center cohort of patients with adrenal tumors of 4 cm or more in diameter during the period of January 1, 2000, through December 31, 2014.

Results: Of 4085 patients with adrenal tumors, 705 (17%) had adrenal masses measuring 4 cm or more in diameter; of these, 373 (53%) were women, with a median age of 59 years (range, 18-91 years) and median tumor size of 5. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S25424548173011
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http://dx.doi.org/10.1016/j.mayocpiqo.2017.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124341PMC
March 2018
18 Reads

Laparoscopic Trans-Abdominal Right Adrenalectomy for a Large Primitive Adrenal Oncocytic Carcinoma: A Case Report and Review of Literature.

Am J Case Rep 2018 Sep 15;19:1096-1102. Epub 2018 Sep 15.

Department of General Surgery, Istituto Clinico Sant'Ambrogio, Milan, Italy.

BACKGROUND Adrenocortical oncocytic neoplasms (AONs) are extremely rare tumors. AONs are classified as: oncocytoma (AO), oncocytic neoplasm of uncertain malignant potential (AONUMP), and oncocytic carcinoma (AOC). Among the 162 reported cases of AONs in the literature, 30 cases were classified as malignant. Read More

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https://www.amjcaserep.com/abstract/index/idArt/910259
Publisher Site
http://dx.doi.org/10.12659/AJCR.910259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152586PMC
September 2018
21 Reads

Adrenal metastasis in sequentially developed combined hepatocellular carcinoma-cholangiocarcinoma: A case report.

Ann Hepatobiliary Pancreat Surg 2018 Aug 31;22(3):287-291. Epub 2018 Aug 31.

Department of Surgery, Seoul National University College of Medicine, Seoul, Korea.

The incidence of combined hepatocellular carcinoma-cholangiocarcinoma (cHCC-CC) in a single patient accounts for only 0.4 to 14% of all primary liver cancer. However, the prognosis of its intrahepatic cholangiocarcinoma (ICC) component is poor. Read More

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http://dx.doi.org/10.14701/ahbps.2018.22.3.287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125274PMC
August 2018
2 Reads

Incidentally detected adrenocortical carcinoma in familial adenomatous polyposis: an unusual presentation of a hereditary cancer syndrome.

BMJ Case Rep 2018 Sep 4;2018. Epub 2018 Sep 4.

Department of Urology, King George's Medical University, Lucknow, Uttar Pradesh, India.

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http://dx.doi.org/10.1136/bcr-2018-226799DOI Listing
September 2018
5 Reads