2,212 results match your criteria Adrenal Adenoma Imaging


"How We Do It" - A Practical Approach to Percutaneous Adrenal Ablation Techniques.

Tech Vasc Interv Radiol 2020 Jun 25;23(2):100676. Epub 2020 May 25.

Miami Cardiac and Vascular Institute, Miami Cancer Institute, Miami, FL. Electronic address:

Incidental adrenal masses are common and are found in 4% of the CT scans. While clinical history, laboratory results, and imaging characteristics are typically sufficient for diagnosis of an adrenal lesion, a biopsy is sometimes warranted. In some cases, adrenal mass ablation is subsequently indicated. Read More

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http://dx.doi.org/10.1016/j.tvir.2020.100676DOI Listing

Precise Mapping of Intra-Adrenal Aldosterone Activities Provides a Novel Surgical Strategy for Primary Aldosteronism.

Hypertension 2020 Jun 15:HYPERTENSIONAHA11914341. Epub 2020 Jun 15.

From the Endocrinology and Diabetes Center, Yokohama Rosai Hospital, Japan (T.K., K.K.K., M.O., T.T., Y.T., H.K., J.S., T.N.).

Segmental selective adrenal venous sampling (sAVS) elucidates an intraadrenal aldosterone activity map (IAMap), which allows us to design a novel surgical treatment strategy for patients with primary aldosteronism. We evaluated the usefulness of sAVS by analyzing 278 patients with whom we had prospectively used IAMap using the criteria of sAVS for surgical indication between 2009 and 2015. We evaluated its diagnostic accuracy using pathological and postsurgical biochemical and clinical outcomes. Read More

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.119.14341DOI Listing

Hepatic adrenal adenoma-rare tumor on right lobe of liver: a case report and literature review.

Authors:
Haibo Yu Yadong He

BMC Surg 2020 Jun 10;20(1):128. Epub 2020 Jun 10.

Department of Hepatobiliary Surgery, Wenzhou Central Hospital, The Dingli Clinical Institute of Wenzhou Medical University, Wenzhou, Zhejiang, People's Republic of China, 325000.

Background: Hepatic adrenal ectopia is a common clinical diagnosis, whereas adrenal tumors developed from hepatic adrenal ectopia are rare. Hepatic adrenal tumors are easily misdiagnosed as hepatic carcinoma and frequently treated by unnecessary operations.

Case Presentation: A 50-year-old female patient was hospitalized due to B-ultrasonic detection of "right focal liver lesions. Read More

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http://dx.doi.org/10.1186/s12893-020-00780-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288671PMC

Adrenal Adenomas versus Metastases: Diagnostic Performance of Dual-Energy Spectral CT Virtual Noncontrast Imaging and Iodine Maps.

Radiology 2020 May 26:192227. Epub 2020 May 26.

From the Department of Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto 860-8556, Japan.

Background Dual-energy CT allows virtual noncontrast (VNC) attenuation and iodine density measurements from contrast material-enhanced examination, potentially enabling adrenal lesion characterization. However, data regarding diagnostic performance remain limited, and combined diagnostic values have never been investigated. Purpose To determine whether VNC attenuation, iodine density, and combination of the two allow reliable differentiation between adrenal adenomas and metastases. Read More

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http://dx.doi.org/10.1148/radiol.2020192227DOI Listing

[An unusual case of severe acute hyponatremia in patient with COVID-19 infection].

Nefrologia 2020 May - Jun;40(3):356-358. Epub 2020 May 8.

Servicio de Nefrología, Hospital Central de la Defensa Gómez Ulla, Madrid, España.

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http://dx.doi.org/10.1016/j.nefro.2020.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205617PMC

Adrenalectomy during pregnancy: A 15-year experience at a tertiary referral center.

Surgery 2020 May 17. Epub 2020 May 17.

Department of Digestive, Hepato-biliary and Endocrine Surgery, Referral Center for Rare Adrenal Diseases, Cochin Hospital, APHP, Paris, France; Faculté de Médecine Paris Descartes, Université Paris Descartes, Sorbonne Paris Cité, France; INSERM Unité 1016, Centre National de la Recherche Scientifique Unité Mixte de Recherche 8104, Institut Cochin, Paris, France.

Background: Adrenal lesions diagnosed during pregnancy remain rare, and their management is challenging because of maternal physiologic modifications, restricted imaging investigations, and contraindications to several treatments. Surgical issues of adrenalectomy during pregnancy and consequences on perinatal outcomes are poorly described. We therefore aimed to report maternal and fetal outcomes after adrenalectomy during pregnancy. Read More

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http://dx.doi.org/10.1016/j.surg.2020.03.019DOI Listing

Pregnancy-induced Cushing's syndrome with an adrenocortical adenoma overexpressing LH/hCG receptors: a case report.

BMC Endocr Disord 2020 May 11;20(1):62. Epub 2020 May 11.

Department of Endocrinology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107 Yanjiang West Road, Guangzhou, 510120, China.

Background: Pregnancy-induced Cushing's syndrome (CS) with an adrenocortical adenoma overexpressing luteinizing hormone (LH)/human choriogonadotropin (hCG) receptors (LHCGR) has been rarely reported in the literatures. This peculiar condition challenges the canonical diagnosis and management of CS.

Case Presentation: A 27-year-old woman (G2P0A1) presented at 20 weeks gestational age (GA) with overt Cushingoid clinical features. Read More

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http://dx.doi.org/10.1186/s12902-020-0539-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216527PMC
May 2020
1.673 Impact Factor

Conned by Conn's: The Manifestation of Conn's Syndrome Post-renal Transplant in a Patient with Polycystic Kidney Disease.

Cureus 2020 Apr 2;12(4):e7512. Epub 2020 Apr 2.

Radiology, Hospital of the University of Pennsylvania, Philadelphia, USA.

We present the case of a 66-year-old African-American male with end-stage renal disease (ESRD) secondary to polycystic kidney disease (PCKD), with well-controlled hypertension. He was placed on peritoneal dialysis for two years before successfully undergoing a cadaveric renal transplant. There was an immediate graft function with no relevant postoperative complications. Read More

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http://dx.doi.org/10.7759/cureus.7512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195196PMC

Utility of the 10 Hounsfield unit threshold for identifying adrenal adenomas: Can we improve?

Am J Surg 2020 Apr 21. Epub 2020 Apr 21.

Division of Surgical Oncology, Department of Surgery, Ohio State University Comprehensive Cancer Center and Ohio State University Wexner Medical Center, USA. Electronic address:

Background: Current recommendations using Hounsfield units (HU) ≤ 10 to identify adrenal adenomas on unenhanced computed tomography (CT) miss 10-40% of benign adenomas. We sought to determine if changing HU threshold and adding absolute percent contrast washout (APW) criteria would identify adrenal adenomas better than current recommendations.

Methods: Imaging characteristics were compared between patients with adenomas (n = 128) and those with non-adenomas (n = 54) after unilateral adrenalectomy. Read More

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http://dx.doi.org/10.1016/j.amjsurg.2020.04.021DOI Listing

Preresection Radiologic Assessment and Imaging Features of 156 Pathologically Proven Adrenal Adenomas.

J Comput Assist Tomogr 2020 May/Jun;44(3):419-425

From the Departments of Diagnostic Radiology.

Purpose: The aims of the study were to assess the typical and atypical radiologic features of pathologically proven adrenal adenomas and to determine the relationship between the radiologic and histopathologic classification.

Methods: We retrospectively studied 156 pathologically proven adrenal adenomas in 154 patients from our institutional databases who have computed tomography (CT) and/or magnetic resonance imaging (MRI) examinations before intervention. We determined the histopathologic diagnosis (typical or atypical) using Weiss scoring and classified the adenomas radiologically into typical, atypical, or indeterminate based on lesion size, precontrast CT attenuation, absolute percentage washout, calcification, and necrosis. Read More

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http://dx.doi.org/10.1097/RCT.0000000000001018DOI Listing

The value of signal intensity on T1-weighted chemical shift magnetic resonance imaging combined with proton magnetic resonance spectroscopy for the diagnosis of adrenal adenomas.

Radiol Bras 2020 Mar-Apr;53(2):86-94

Escola Paulista de Medicina da Universidade Federal de São Paulo (EPM-Unifesp), São Paulo, SP, Brazil.

Objective: To investigate the advantages of using modified signal intensity measurements on chemical shift imaging alone or in conjunction with proton magnetic resonance spectroscopy in the differential diagnosis of adrenal adenomas.

Materials And Methods: This was a prospective study involving 97 patients with adrenal nodules or masses. The signal intensity index (SII) was calculated as [( ∕ ()] × . Read More

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http://dx.doi.org/10.1590/0100-3984.2019.0095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170587PMC

Pericardial Effusion as an Initial Presentation of Panhypopituitarism.

Eur J Case Rep Intern Med 2020 24;7(4):001478. Epub 2020 Feb 24.

Department of Internal Medicine, Hospital Garcia de Orta, Almada, Portugal.

Pericardial effusion has a broad spectrum of clinical presentation, ranging from an incidental finding on imaging to a potentially fatal emergency such as pericardial tamponade, the most severe presentation. The authors present a case of a middle-aged male hospitalized due to shortness of breath. Initial work-up was positive for massive pericardial effusion with haemodynamic compromise. Read More

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http://dx.doi.org/10.12890/2020_001478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162561PMC
February 2020

Reliability of adrenal computed tomography in predicting the functionality of adrenal incidentaloma.

Niger Postgrad Med J 2020 Apr-Jun;27(2):101-107

Department of Biochemistry, College of Medicine, University of Basrah, Basrah, Iraq.

Background: Adrenal incidentaloma (AI) is an adrenal mass discovered accidentally during abdominal or chest imaging techniques not aimed to adrenal gland assessment. Guidelines suggested confirming the benignity of AI radiologically and excluding hormonal dysfunctions. This study evaluated the reliability of computed tomography (CT) scan radiological parameters in predicting the functionality of AI. Read More

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http://dx.doi.org/10.4103/npmj.npmj_156_19DOI Listing

Clinical course of adrenal myelolipoma: A long-term longitudinal follow-up study.

Clin Endocrinol (Oxf) 2020 Jul 23;93(1):11-18. Epub 2020 Apr 23.

Division of Endocrinology, Diabetes, and Nutrition, Mayo Clinic, Rochester, MN, USA.

Objective: We aimed to describe clinical course of myelolipoma and to identify predictors of tumour growth and need for surgery.

Design: A retrospective study.

Patients: Consecutive patients with myelolipoma. Read More

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http://dx.doi.org/10.1111/cen.14188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292791PMC

Role of Mast Cells in the Control of Aldosterone Secretion.

Horm Metab Res 2020 Jun 25;52(6):412-420. Epub 2020 Mar 25.

Normandie University, UNIROUEN, INSERM, DC2N, Rouen, France.

Mast cells are immune cells present in adrenals from various species. Proliferation and activation of adrenal mast cells seem to be influenced by environment, since they increase during summer and in response to sodium restriction in frogs and mouse, respectively. Although the physiological factors regulating adrenal mast cell activity have not been identified, they might involve neurotransmitters and the renin-angiotensin system. Read More

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http://dx.doi.org/10.1055/a-1119-1063DOI Listing

Imaging CXCR4 expression in patients with suspected primary hyperaldosteronism.

Eur J Nucl Med Mol Imaging 2020 Mar 23. Epub 2020 Mar 23.

Division of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria.

Purpose: It is challenging to differentiate unilateral aldosterone-producing adenoma (APA) from bilateral idiopathic adrenal hyperplasia (IAH) and nonfunctional adrenal adenoma (NFA) in primary aldosteronism (PA). In a first primarily ex vivo study detection, CXC chemokine receptor type 4 (CXCR4) expression has been shown to be a valuable tool for the detection of APA. In this study, we aimed to clinically evaluate CXCR4 imaging with Ga-pentixafor PET/CT for detecting APA. Read More

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http://dx.doi.org/10.1007/s00259-020-04722-0DOI Listing

Primary aldosteronism.

Gland Surg 2020 Feb;9(1):14-24

Department of General Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

Primary aldosteronism (PA) is a common cause of secondary hypertension caused by excessive and inappropriate secretion of the hormone aldosterone from one or both adrenal glands. The prevalence of PA ranges from 10% in the general hypertensive population to 20% in resistant hypertension, yet only a small fraction of patients is diagnosed. Disease and symptom recognition, screening in indicated populations, multidisciplinary communication, and appropriate imaging and biochemical workup can identify patients who might benefit from effective and targeted treatment modalities. Read More

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http://dx.doi.org/10.21037/gs.2019.10.23DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082264PMC
February 2020

Immediate Results and Long-Term Outcomes Following Percutaneous Radiofrequency Ablation of Unilateral Aldosterone-Producing Adenoma.

Acta Cardiol Sin 2020 Mar;36(2):160-167

Division of Cardiology, Department of Internal Medicine.

Background: The aim of this study was to evaluate early and long-term clinical and laboratory findings in patients with resistant hypertension secondary to aldosterone-producing adenoma (APA) treated with radiofrequency ablation (RFA).

Methods: From July 2009 to September 2017, eight adult patients underwent percutaneous computed tomography (CT)-guided RFA for APA. The safety, efficacy and complications of the procedure were determined. Read More

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http://dx.doi.org/10.6515/ACS.202003_36(2).20190812CDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062809PMC

Adrenal Adenoma Anarchy: A Case of an ACTH-Secreting Pheochromocytoma.

Case Rep Endocrinol 2020 26;2020:4869467. Epub 2020 Feb 26.

Department of Medicine, Department of Endocrinology, San Antonio Military Medical Center, 3551 Roger Brooke Drive, JBSA Fort Sam Houston, San Antonio, TX 78234, USA.

. Pheochromocytomas are rare neuroendocrine tumors that arise from sympathetic adrenomedullary chromaffin tissue. Depending on the amount of catecholamines they secrete, they have variable presentations. Read More

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http://dx.doi.org/10.1155/2020/4869467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063192PMC
February 2020

An Incidental Diagnosis of Microscopic Renal Angiomyolipoma Completely Excised on Renal Biopsy: A Case Report.

Am J Case Rep 2020 Mar 15;21:e921353. Epub 2020 Mar 15.

Department of Diagnostic Pathology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan.

BACKGROUND Microscopic tumor foci have been detected incidentally on renal biopsy, including renal cell carcinoma and renomedullary interstitial cell tumor (medullary fibroma). A report is presented of a case of an incidental finding of microscopic renal angiomyolipoma that was diagnosed and completely excised on core needle biopsy. CASE REPORT A 44-year-old woman was referred to our hospital for evaluation of persistent mild proteinuria. Read More

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http://dx.doi.org/10.12659/AJCR.921353DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7092777PMC

Controversies and advances in adrenal venous sampling in the diagnostic workup of primary aldosteronism.

Best Pract Res Clin Endocrinol Metab 2020 Feb 22:101400. Epub 2020 Feb 22.

Endocrine Hypertension Research Centre, University of Queensland Diamantina Institute, Princess Alexandra Hospital, 199 Ipswich Road, Woolloongabba, Brisbane, 4102, Australia. Electronic address:

Adrenal venous sampling (AVS) is a key part of the diagnostic workup of primary aldosteronism, distinguishing unilateral from bilateral disease and determining treatment options. Although AVS is a well-established procedure, many aspects remain controversial, including optimal patient selection for the procedure and exactly how AVS is performed and interpreted. Despite the controversies, a growing body of evidence supports the use of AVS in most patients with primary aldosteronism, though some specific patient groups may be able to forego AVS and proceed directly to treatment. Read More

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http://dx.doi.org/10.1016/j.beem.2020.101400DOI Listing
February 2020

Markers of Subclinical Cardiovascular Disease in Patients with Adrenal Incidentaloma.

Medicina (Kaunas) 2020 Feb 10;56(2). Epub 2020 Feb 10.

Clinic of Endocrinology, Diabetology and Internal Medicine, School of Medicine, Collegium Medicum, University of Warmia and Mazury in Olsztyn, 10-900 Olsztyn, Poland.

Due to the growing availability of imaging examinations the percentage of patients with incidentally diagnosed adrenal tumors has increased. The vast majority of these lesions are benign, non-functioning adenomas, although according to various estimates even up to 30%-50% of patients with adrenal incidentaloma may present biochemical hypercortisolemia, without typical clinical features of Cushing's syndrome. Adrenal adenomas secreting small amounts of glucocorticoids may cause morphological and functional changes in the myocardium and blood vessels. Read More

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http://dx.doi.org/10.3390/medicina56020069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074127PMC
February 2020

State-of-the-art MR Imaging of Fat-containing Focal Lesions of the Liver.

Curr Med Imaging Rev 2019 ;15(5):435-442

Department of Radiology I, Maria Skłodowska-Curie Memorial Cancer Centre, Institute of Oncology, Ul. Roentgena 5, 02-781 Warszawa, Poland.

Background: Fat can be identified in numerous liver lesions, and usually is not a specific finding. Distinguishing between different kinds of fatty deposits is an important part of differential diagnosis. Magnetic Resonance Imaging (MRI) is superior to other imaging techniques because it allows distinguishing intracellular from macroscopic fat. Read More

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http://dx.doi.org/10.2174/1573405614666171218154838DOI Listing
January 2019

AN UNEXPECTED COMBINATION OF PROLACTINOMA AND SEPTO-OPTIC DYSPLASIA.

AACE Clin Case Rep 2019 Sep-Oct;5(5):e282-e286. Epub 2019 Jun 7.

Objective: To describe the unusual finding of pituitary adenoma in a patient with septo-optic dysplasia (SOD).

Methods: We describe the clinical presentation, biochemical and radiological evaluation, treatment, and outcomes of a patient with macroprolactinoma and previously undiagnosed SOD.

Results: A 41-year-old woman with optic nerve hypoplasia and growth hormone deficiency presented with new-onset galactorrhea, polyuria, and polydipsia. Read More

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http://dx.doi.org/10.4158/ACCR-2019-0127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876952PMC

AN INCIDENTAL COLLISION TUMOR OF THE SELLA TURCICA.

AACE Clin Case Rep 2019 Jul-Aug;5(4):e247-e249. Epub 2019 Mar 3.

Objective: To present a case describing an incidentally discovered pituitary mass that was found to be a collision tumor containing 2 distinct histologic cell types: () a growth hormone (GH)-secreting pituitary adenoma, and () a gangliocytoma.

Methods: Sellar gangliocytomas are very rare benign neuroblastic tumors that originate from the posterior pituitary. The majority are associated with pituitary adenomas. Read More

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http://dx.doi.org/10.4158/ACCR-2019-0013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873830PMC

Mass Spectrometry Imaging Establishes 2 Distinct Metabolic Phenotypes of Aldosterone-Producing Cell Clusters in Primary Aldosteronism.

Hypertension 2020 Mar 20;75(3):634-644. Epub 2020 Jan 20.

Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Germany (L.S.M., M.R., T.A.W.).

Aldosterone-producing adenomas (APAs) are one of the main causes of primary aldosteronism and the most prevalent surgically correctable form of hypertension. Aldosterone-producing cell clusters (APCCs) comprise tight nests of zona glomerulosa cells, strongly positive for CYP11B2 (aldosterone synthase) in immunohistochemistry. APCCs have been suggested as possible precursors of APAs because they frequently carry driver mutations for constitutive aldosterone production, and a few adrenal lesions with histopathologic features of both APCCs and APAs have been identified. Read More

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.119.14041DOI Listing

[The Value of Postural Stimulation Test Combined with Adrenal CT in the Diagnosis of Aldosterone-producing Adenoma].

Sichuan Da Xue Xue Bao Yi Xue Ban 2020 Jan;51(1):87-91

Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu 610041, China.

Objective: Adrenal vein sampling (AVS) and pathological report were selected as gold standard to assess the value of adrenal CT scan combined with postural stimulation test in diagnosing aldosterone-producing adenoma.

Methods: The clinical data of primary aldosteronism (PA) patients including aldosterone-producing adenoma (APA) and idiopathic hyperaldosteronism (IHA) were retrospectively collected in the West China Hospital of Sichuan University. The sensitivity and specificity of adrenal CT scan combined with postural stimulation test in diagnosing APA were studied. Read More

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http://dx.doi.org/10.12182/20200160604DOI Listing
January 2020

Adrenal Cavernous Hemangioma: A Rarely Perceived Pathology-Case Illustration and Review of Literature.

Case Rep Pathol 2019 17;2019:8463890. Epub 2019 Dec 17.

Department of Surgery, Division of Urology, American University of Beirut-Medical Center, Beirut 1107 2020, Lebanon.

Cavernous hemangiomas are endothelial tumors that rarely affect the adrenal glands. Most of these tumors remain silent and are incidentally found on abdominal imaging. Hardly ever, these tumors are endocrinologically functional. Read More

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http://dx.doi.org/10.1155/2019/8463890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944974PMC
December 2019

Adrenocortical carcinoma masquerading as pheochromocytoma: a histopathologic dilemma.

Endocrinol Diabetes Metab Case Rep 2020 Jan 8;2020. Epub 2020 Jan 8.

Pediatric Oncology Branch, Rare Tumor Initiative, Center for Cancer Research, National Cancer Institute, Clinical Center.

Summary: Adrenocortical carcinoma (ACC) is an aggressive cancer that originates in the cortex of the adrenal gland and generally has a poor prognosis. ACC is rare but can be more commonly seen in those with cancer predisposition syndromes (e.g. Read More

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http://dx.doi.org/10.1530/EDM-19-0147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993251PMC
January 2020

[Multiple endocrine neoplasia type 2A in a family].

Orv Hetil 2020 Jan;161(2):75-79

Belgyógyászati Intézet, Endokrinológia Tanszék, Debreceni Egyetem, Általános Orvostudományi Kar Debrecen, Nagyerdei krt. 98., 4032.

The authors present the case of a multiplex endocrine neoplasia type 2A (MEN2A). The 55-year-old woman underwent detailed examinations for abdominal complaints. Bilateral adrenal masses and thyroid nodular goiter were found. Read More

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http://dx.doi.org/10.1556/650.2020.31595DOI Listing
January 2020

Laparoscopic Excision of the Retroperitoneal Mullerian Cyst in a Different Location.

J Pediatr Adolesc Gynecol 2020 Jun 23;33(3):318-320. Epub 2019 Dec 23.

Department of Pediatric Surgery, Faculty of Medicine, Dokuz Eylül University, İzmir, Turkey.

Background: Herein, we report laparoscopic excision of a retroperitoneal Mullerian cyst, which is uniquely located medial to the left adrenal gland, mimicking adrenal adenoma in an adolescent girl.

Case: A healthy 13-year-old adolescent girl presented with secondary amenorrhea. Ultrasound and magnetic resonance imaging showed a solid-cystic mass medial to the left adrenal gland. Read More

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http://dx.doi.org/10.1016/j.jpag.2019.12.009DOI Listing
June 2020
1.812 Impact Factor

Clinical analysis of adrenal lesions larger than 5 cm in diameter (an analysis of 251 cases).

World J Surg Oncol 2019 Dec 16;17(1):220. Epub 2019 Dec 16.

Department of Urology, The First Affiliated Hospital of Dalian Medical University, Dalian, China.

Background: To describe the pathological distribution, imaging manifestations, and surgical managements and prognosis of large adrenal tumors (LATs) ≥ 5 cm METHODS: A total of 251 patients with LATs were analyzed on the basis of pathological or clinical diagnosis. Regarding surgery, open adrenalectomy was performed on 89 patients, and laparoscopic adrenalectomy was performed on 89 patients. Thirty-two patients with bilateral tumors were analyzed in terms of clinical characteristics. Read More

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http://dx.doi.org/10.1186/s12957-019-1765-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6916431PMC
December 2019

Primary aldosteronism in Klinefelter's syndrome: two cases.

Endocrinol Diabetes Metab Case Rep 2019 Dec 16;2019. Epub 2019 Dec 16.

Departments of Endocrinology and Hypertension, Tokyo, Japan.

Summary: Primary aldosteronism (PA) is more common than expected. Aberrant adrenal expression of luteinizing hormone (LH) receptor in patients with PA has been reported; however, its physiological role on the development of PA is still unknown. Herein, we report two unique cases of PA in patients with untreated Klinefelter's syndrome, characterized as increased serum LH, suggesting a possible contribution of the syndrome to PA development. Read More

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http://dx.doi.org/10.1530/EDM-19-0126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935713PMC
December 2019

Presence of aberrant adrenocorticotropic hormone precursors in two cases of McCune-Albright syndrome.

Endocr J 2020 Mar 4;67(3):353-359. Epub 2019 Dec 4.

Department of Endocrinology and Metabolism, Hirosaki University Graduate School of Medicine and Hospital, Hirosaki, Aomori, Japan.

McCune-Albright syndrome (MAS) is a rare disorder. MAS is classically defined by the occurrence of fibrous dysplasia, café-au-lait skin macules, and precocious puberty. In addition to precocious puberty, other hyperfunctioning endocrinopathies may occur. Read More

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http://dx.doi.org/10.1507/endocrj.EJ19-0449DOI Listing

Adrenocortical Scintigraphy With SPECT/CT for the Diagnosis of Hepatic Adrenal Rest.

Clin Nucl Med 2020 Apr;45(4):e192-e194

From the Departments of Radiology.

Hepatic adrenal rest include ectopic adrenal tissue in the liver and adrenohepatic fusion. Long-lasting hyperstimulation of that tissue induces hyperplasia sometimes simulating true tumors. True autonomic tumors originating from ectopic adrenal tissue with or without hyperfunction are rare. Read More

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http://dx.doi.org/10.1097/RLU.0000000000002852DOI Listing

A laparoscopic treatment of a suspicious adrenal mass revealing an unsual cause of adrenal incidentaloma.

Pan Afr Med J 2019 12;34:28. Epub 2019 Sep 12.

Department of Endocrinology and Diabetology, University Hospital of Fez, Fez, Morocco.

Schwannomas are rare tumors, usually benign, originating from the Schwann sheath of the peripheral or cranial nerves. They are an extremely uncommon cause of adrenal incidentaloma. It is difficult to diagnose adrenal schwannoma preoperatively by imaging alone due of their aspect suspect on it. Read More

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http://dx.doi.org/10.11604/pamj.2019.34.28.18239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859016PMC
December 2019

Pure Androgen-Secreting Adrenocortical Carcinoma Presenting with Hypoglycemia.

Arch Iran Med 2019 09 1;22(9):527-530. Epub 2019 Sep 1.

Department of Internal Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

Adrenocortical carcinoma (ACC) is a rare and aggressive malignancy. Most patients present with steroid hormone excess or abdominal mass effect. Pure androgen-secreting ACCs are rare, while hypoglycemia is an unusual presentation of this malignancy. Read More

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September 2019
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A Diagnostic Approach to Adrenocortical Tumors.

Surg Pathol Clin 2019 Dec 27;12(4):967-995. Epub 2019 Sep 27.

Department of Pathology, University Health Network, 200 Elizabeth Street, 11th Floor, Toronto, Ontario M5G2C4, Canada; Department of Laboratory Medicine and Pathobiology, The University of Toronto, Toronto, Ontario, Canada. Electronic address:

Adrenocortical tumors range from primary bilateral micronodular or macronodular forms of adrenocortical disease to conventional adrenocortical adenomas and carcinomas. Accurate classification of these neoplasms is critical given the varied pathogenesis, clinical behavior, and outcome of these different lesions. Confirmation of adrenocortical origin, diagnosing malignancy, providing relevant prognostic information in adrenocortical carcinoma, and correlation of laboratory results with clinicopathologic findings are among the important responsibilities of pathologists who evaluate these lesions. Read More

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http://dx.doi.org/10.1016/j.path.2019.08.005DOI Listing
December 2019

A case report of idiopathic hyperaldosteronism characterized by bilateral adrenal adenoma.

Medicine (Baltimore) 2019 Oct;98(43):e17418

Department of Endocrinology, First Affiliated Hospital of Baotou Medical Collage, Inner Mongolia University of Science and Technology, Baotou 014010, Inner Mongolia, China.

Rationale: Primary aldosteronism (PA) comprises 2 main subtypes: unilateral aldosterone-producing adenoma (APA) and idiopathic hyperaldosteronism or named as bilateral adrenal hyperplasia (BAH). An accurate discrimination between APA and BAH is crucial because the former is treated with adrenalectomy (ADX) and the latter is primarily by aldosterone antagonists. We report a case of idiopathic hyperaldosteronism characterized by BAH. Read More

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http://dx.doi.org/10.1097/MD.0000000000017418DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824822PMC
October 2019
1 Read
5.723 Impact Factor

Cerebral Venous Sinus Thrombosis After Transsphenoidal Resection: A Rare Complication of Cushing Disease-Associated Hypercoagulability.

World Neurosurg 2020 Feb 19;134:86-89. Epub 2019 Oct 19.

Department of Neurosurgery, Neurological Institute, Cleveland Clinic, Cleveland, Ohio, USA; Minimally Invasive Cranial Base and Pituitary Surgery, Rosa Ella Burkhardt Brain Tumor and Neuro-Oncology Center, Cleveland Clinic, Cleveland, Ohio, USA; Section of Rhinology, Sinus, and Skull Base Surgery, Head and Neck Institute, Cleveland Clinic, Cleveland, Ohio, USA. Electronic address:

Background: Venous thromboembolism is a well-known complication of Cushing syndrome. Deep vein thrombosis and pulmonary embolic events have been widely reported in patients with Cushing syndrome, but cerebral venous sinus thrombosis remains a much less common finding in these patients.

Case Description: We report one of the first cases of cerebral venous sinus thrombosis in a patient with Cushing disease. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.10.077DOI Listing
February 2020
1 Read
2.417 Impact Factor

A Descriptive Study to Find Possible Correlation between Pituitary Magnetic Resonance Image Findings and Abnormal Pituitary Hormones: A Retrospective Single Centre Study in Saudi Community Based Hospital.

J Assoc Physicians India 2019 Oct;67(10):29-32

Department of Endocrinology.

Background: Data on pituitary Magnetic Resonance Imaging (MRI) in patients with abnormal pituitary hormones in Saudi Arabia are very scarce.

Objective: To define the frequency of normal pituitary MRI in patients with abnormal pituitary hormones in a well-defined population.

Design: Retrospective analysis of radiological and hormonal data of patients with pituitary MRI between January 2008 and December 2015. Read More

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October 2019
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Magnetic resonance imaging of adrenal gland: state of the art.

Gland Surg 2019 Sep;8(Suppl 3):S223-S232

Department of Medicine and Surgery, Unit of Radiologic Science, University of Parma, Maggiore Hospital, Parma, Italy.

Detection of adrenal lesions, because of the widespread use of imaging and especially high-resolution imaging procedures, is increased. Because of the importance to characterize those findings, magnetic resonance imaging (MRI), in particular chemical shift imaging (CSI), is useful to distinguish whether a lesion is benignant or malignant and to avoid further diagnostic or surgical procedures. It represents the first choice of imaging in patient like children or pregnant women, and a valid complement to other imaging techniques like CT or PET/CT. Read More

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http://dx.doi.org/10.21037/gs.2019.06.02DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755942PMC
September 2019
3 Reads

Adrenal Adenoma-Hemangioma Collision Tumor: Description of Two Cases.

J Radiol Case Rep 2019 Jun 30;13(6):1-12. Epub 2019 Jun 30.

Department of Diagnostic Imaging and Laboratory Medicine, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.

Adrenal collision tumors are rare clinical entities referring to separate coexisting adjacent tumors involving an adrenal gland with sharp demarcation between the two and without a substantial histologic admixture at the interface. Most of the adrenal collision tumors described are combinations of adenoma and metastasis or adenoma and myelolipoma. We report two cases of a 63-year-old male and a 76-year-old female patient with a presumable exceedingly rare adrenal hemangioma-adenoma collision tumor. Read More

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http://dx.doi.org/10.3941/jrcr.v13i6.3691DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742450PMC
June 2019
4 Reads

Incremental value of F-fluorocholine PET/CT in comparison with Ga-DOTA PET/CT in adrenal adenoma localization in a MEN1 patient.

Rev Esp Med Nucl Imagen Mol 2020 Jan - Feb;39(1):45-46. Epub 2019 Sep 21.

Department of Nuclear Medicine, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, RP China; Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province, Luzhou, Sichuan, RP China. Electronic address:

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http://dx.doi.org/10.1016/j.remn.2019.03.004DOI Listing
September 2019
3 Reads

Characteristic CT features of pheochromocytomas - probability model calculation tool based on a multicentric study.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2019 Sep 23;163(3):212-219. Epub 2019 Sep 23.

Department of Imaging Methods, University Hospital Pilsen and Faculty of Medicine in Pilsen, Charles University, Czech Republic.

Objectives: The aim of the study was to evaluate the CT features of adrenal tumors in an effort to identify features specific to pheochromocytomas and second, to define a feasible probability calculation model.

Methods: This multicentric retrospective study included patients from the period 2003 to 2017 with an appropriate CT examination and a histological diagnosis of an adrenal adenoma, pheochromocytoma, adrenocortical carcinoma, or metastasis. In total, 346 patients were suitable for the CT image analysis, which included evaluation of the largest diameter, the shape of the lesion, the presence of central necrosis and its margins, and the presence of an enhancing peripheral rim ("ring sign"). Read More

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http://dx.doi.org/10.5507/bp.2019.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875693PMC
September 2019
7 Reads

Adrenal cortical adenoma: current update, imaging features, atypical findings, and mimics.

Abdom Radiol (NY) 2020 04;45(4):905-916

Departments of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, 1400 Pressler Street, Houston, TX, 77030, USA.

Adrenal adenoma is the most common adrenal lesion. Due to its wide prevalence, adrenal adenomas may demonstrate various imaging features. Thus, it is important to identify typical and atypical imaging features of adrenal adenomas and to be able to differentiate atypical adrenal adenomas from potentially malignant lesions. Read More

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http://dx.doi.org/10.1007/s00261-019-02215-9DOI Listing
April 2020
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Simultaneous presentation of parathyroid carcinoma, papillary thyroid cancer and ACTH-independent hypercortisolism due to benign cortical adenoma.

BMJ Case Rep 2019 Sep 5;12(9). Epub 2019 Sep 5.

Oncology and Metabolism, University of Sheffield, Sheffield, UK.

A 46-year-old woman presented with hypertension and renal disease. Investigations showed severe hypercalcaemia due to primary hyperparathyroidism. Imaging demonstrated renal calculi and an incidental left adrenal lesion. Read More

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http://dx.doi.org/10.1136/bcr-2019-230438DOI Listing
September 2019
6 Reads

Uptake of 18F-FDG in Adrenal Adenomas Is Associated With Unenhanced CT Value and Constituent Cells.

Clin Nucl Med 2019 Dec;44(12):943-948

From the Departments of Clinical Radiology.

Purpose: The purposes of this study were to investigate the correlation between unenhanced CT attenuation values and F-FDG uptake in adrenal adenomas, and to clarify the mechanism of FDG uptake in adrenal adenomas based on immunohistochemical findings.

Materials And Methods: In 57 adrenal adenomas, the correlation between SUVmax on F-FDG PET and unenhanced CT attenuation was retrospectively investigated. In the 11 surgically resected nodules, the clear cell ratio (CCR) and expression levels of glucose transporters (GLUTs) 1 to 4 were pathologically evaluated. Read More

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http://dx.doi.org/10.1097/RLU.0000000000002759DOI Listing
December 2019

Diverse Responses of Autoantibodies to the Angiotensin II Type 1 Receptor in Primary Aldosteronism.

Hypertension 2019 10 3;74(4):784-792. Epub 2019 Sep 3.

From the Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, Ludwig-Maximilians-Universität München, Germany (T.A.W., D.J., Y.Y., P.R., N.N., L.S., M.B., F.B., M.R.).

Primary aldosteronism is a common form of endocrine hypertension mainly caused by a unilateral aldosterone-producing adenoma (APA) or bilateral adrenal hyperplasia (BAH). AT1R-Abs (autoantibodies to the angiotensin II type 1 receptor) have been reported in patients with disorders associated with hypertension. Our objective was to assess AT1R-Ab levels in patients with primary aldosteronism (APA, n=40 and BAH, n=40) relative to patients with primary hypertension (n=40), preeclampsia (n=23), and normotensive individuals (n=25). Read More

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.119.13156DOI Listing
October 2019
2 Reads