6,390 results match your criteria Adnexal Tumors


Fast-growing immature ovarian teratoma during pregnancy: a case report and a review of the literature.

BMC Pregnancy Childbirth 2022 Jun 27;22(1):519. Epub 2022 Jun 27.

Department of Gynecology and Obstetrics, West China Second University Hospital, Sichuan University, Sichuan Province, No. 20 Section Three, South Renmin Road, Chengdu, 610041, People's Republic of China.

Background: Immature ovarian teratoma is one of the three common malignant ovarian germ cell tumors. However, immature ovarian teratoma in pregnancy is very rare. Due to the rare occurrence, there is little evidence regarding its diagnosis, optimal management, and prognosis. Read More

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Recurrent Cylindroma of the Scalp: A Cytomorphological Evaluation at Fine Needle Aspiration Cytology.

Cureus 2022 May 19;14(5):e25152. Epub 2022 May 19.

Pathology, Adichunchanagiri Institute of Medical Sciences, Adichunchanagiri University, BG Nagara, Mandya, IND.

Specific diagnosis of adnexal tumours at fine needle aspiration cytology (FNAC) is challenging. In a recurrent scalp tumour, a startling array of lesions ranging from benign to malignant tumours fall into differential diagnosis. Accurate preoperative diagnosis is essential for planning management and to improve clinical outcome. Read More

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Clinicopathologic Characteristics Associated with Prognosis in Ocular Extranodal Marginal Zone B Cell Lymphoma.

Medicina (Kaunas) 2022 Jun 17;58(6). Epub 2022 Jun 17.

Department of Pathology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan 05505, Korea.

: Extranodal marginal zone lymphoma of the mucosa-associated lymphoid tissue (MALT) type is the most common subtype of the ocular adnexal lymphoma. Despite its excellent prognosis, some patients experience partial remission or progressive disease. We aimed to evaluate clinicopathologic differences in the treatment responder group by comparing complete remission (CR) and non-complete remission (non-CR). Read More

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Panfolliculoma: Report of the Youngest Case and Literature Review of Its Histopathologic Variants.

Life (Basel) 2022 Jun 13;12(6). Epub 2022 Jun 13.

Department of Dermatology, Chi Mei Medical Center, Tainan 71004, Taiwan.

: Panfolliculoma (PF) is a relative rare, benign follicular tumor comprised of all elements of the hair follicle, with a limited number of cases reported in the literature. Articles on the demographic and pathological analysis of this tumor are also lacking. : In this report, we presented an unusual case of cystic PF on the back of a 14-year-old male, and we performed a thorough literature review and analysis of all previously reported cases. Read More

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Laparoscopic Treatment of Benign Adnexal Masses During Pregnancy: A Comprehensive Evaluation of Treatment Basics, Efficacy and Surgical Techniques.

Surg Technol Int 2022 Jun 23;40. Epub 2022 Jun 23.

Department of Minimally Invasive Surgery Unit of Centro Hospitalar Universitário do Porto, Porto, Portugal.

This review summarizes the evidence-based recommendations for how to approach and laparoscopically treat adnexal masses during pregnancy. We conducted a comprehensive review of studies related to the laparoscopic management of adnexal masses during pregnancy. Selected studies were independently reviewed by two authors. Read More

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Non-sebaceous lymphadenoma arising as a painless subcutaneous nodule on the eyebrow.

J Cutan Pathol 2022 Jun 19. Epub 2022 Jun 19.

Department of Dermatology and Dermatopathology, Oregon Health & Science University, Portland, OR.

Salivary gland tumors can rarely present on skin excision specimens and can pose a diagnostic challenge to dermatopathologists. We present an exceptional case of a salivary gland type non-sebaceous lymphadenoma presenting as a painless subcutaneous nodule on the right medial eyebrow of a 16-year-old male, mimicking a primary cutaneous adnexal neoplasm. Histologic evaluation revealed a well-circumscribed to partially encapsulated nodule with a marked lymphoid infiltrate including reactive germinal centers. Read More

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Direct intracranial invasion of eccrine spiradenocarcinoma of the scalp: a case report and literature review.

BMC Neurol 2022 Jun 18;22(1):223. Epub 2022 Jun 18.

Department of Neurosurgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, Aichi, 466-8550, Japan.

Background: Eccrine spiradenocarcinoma (SC), also known as malignant eccrine spiradenoma, is a rare malignant cutaneous adnexal neoplasm arising from long-standing benign eccrine spiradenoma. Malignant skin tumors rarely show direct intracranial invasion. However, once the intracranial structure is infiltrated, curative excision with sufficient margins can become extremely difficult, particularly when the venous sinuses are involved. Read More

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Sebaceous carcinoma of the lip: a case report and review of the literature.

J Med Case Rep 2022 Jun 18;16(1):241. Epub 2022 Jun 18.

Department of Clinical and Experimental Medicine, University of Foggia, Via Carelli 28, 71100, Foggia, Italy.

Background: Sebaceous carcinoma is a very rare, aggressive, malignant tumor arising in the adnexal epithelium of the sebaceous gland. Sebaceous carcinoma in the oral cavity is extremely rare, with only 14 cases reported in literature. We reported the fourth case of sebaceous carcinoma involving the lip CASE PRESENTATION: A 71-year-old Caucasian male smoker presented an ulcerated lesion in the lateral region of the lower lip. Read More

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Sebaceous carcinoma of trunk with bilateral axillary lymph node metastasis: a rare presentation of malignant adnexal tumor in young adult.

J Surg Case Rep 2022 Jun 14;2022(6):rjac280. Epub 2022 Jun 14.

Department of Pathology, B.P. Koirala Institute of Health Sciences, Dharan, Nepal.

Malignant adnexal tumors of skin are rare. Sebaceous carcinoma-a rare and aggressive cutaneous tumor-is frequently located in the periorbital region. Malignant adnexal tumors of sebaceous carcinoma type on trunk with axillary lymph node and distant metastasis in young adult is rare. Read More

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"Kissing" basaloid follicular hamartomas of the eyelid.

J Cutan Pathol 2022 Jun 14. Epub 2022 Jun 14.

The Warren Alpert Medical School of Brown University, Department of Dermatology.

Basaloid follicular hamartomas (BFH) are rare, benign, cutaneous adnexal tumors characterized by branching cords and anastomosing strands of basaloid cells in a loose, fibrous stroma. BFH exhibit variable clinical presentations although they are commonly observed as skin to flesh colored papules and are diagnosed based on histological features. Common systemic diseases associated with BFH include alopecia, myasthenia gravis, and palmoplantar pitting. Read More

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The value of Copenhagen Index in the diagnosis of malignant adnexal tumors: a meta-analysis.

Int J Gynaecol Obstet 2022 Jun 13. Epub 2022 Jun 13.

Department of Neonatal Pediatrics, Affiliated Hospital of Guilin Medical College, Guilin, 541001, China.

Background: Ovarian cancer is a common gynecological malignant tumor. Early diagnosis is very important for the prognosis of ovarian cancer patients.

Objective: To evaluate the accuracy of Copenhagen Index (CPH-I) in detecting malignant adnexal tumors, and to compare the diagnostic accuracy of CPH-I and Risk of Ovarian Malignancy Algorithm (ROMA). Read More

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Extramedullary haematopoiesis presenting as an adnexal mass in a patient with β-thalassaemia.

BMJ Case Rep 2022 Jun 10;15(6). Epub 2022 Jun 10.

Department of Gynaecological Ultrasound and Prenatal Diagnostics, Women' Hospital, University Hospital of Basel, Basel, Switzerland.

Solid masses of the ovaries raise the suspicion of malignancy or metastasis and require histological diagnosis. Extramedullary haematopoesis (EMH) is a rare histological finding of a mass of the adnexa. The sonographic pattern of EMH has rarely been described in the literature. Read More

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Diagnostic Performance of the Ovarian-Adnexal Reporting and Data System (O-RADS) Ultrasound Risk Score in Women in the United States.

JAMA Netw Open 2022 Jun 1;5(6):e2216370. Epub 2022 Jun 1.

University of Wisconsin-Madison, Madison.

Importance: The American College of Radiology (ACR) Ovarian-Adnexal Reporting and Data System (O-RADS) ultrasound (US) risk scoring system has been studied in a selected population of women referred for suspected or known adnexal lesions. This population has a higher frequency of malignant neoplasms than women presenting to radiology departments for pelvic ultrasonography for a variety of indications, potentially impacting the diagnostic performance of the risk scoring system.

Objective: To evaluate the risk of malignant neoplasm and diagnostic performance of O-RADS US risk scoring system in a multi-institutional, nonselected cohort. Read More

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Fine needle aspiration cytopathology of eccrine spiradenoma.

J Am Soc Cytopathol 2022 May 10. Epub 2022 May 10.

Department of Pathology, The Ohio State University Wexner Medical Center, James Cancer Hospital and Solove Research Institute, Columbus, Ohio. Electronic address:

Introduction: Eccrine spiradenoma (ES) is a rare benign cutaneous adnexal tumor. The aim of our study was to discuss the clinical presentation, cytomorphologic features, and differential diagnosis of a series of 3 cases of ES diagnosed by fine needle aspiration (FNA).

Materials And Methods: The pathology databases were searched for cases of ES diagnosed by FNA and confirmed by follow-up surgical excision. Read More

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Analytical Validation of a Deep Neural Network Algorithm for the Detection of Ovarian Cancer.

JCO Clin Cancer Inform 2022 06;6:e2100192

Aspira Women's Health, Trumbull, CT.

Purpose: Early detection of ovarian cancer, the deadliest gynecologic cancer, is crucial for reducing mortality. Current noninvasive risk assessment measures include protein biomarkers in combination with other clinical factors, which vary in their accuracy. Machine learning can be applied to optimizing the combination of these features, leading to more accurate assessment of malignancy. Read More

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Rare giant female adnexal tumor of probable Wolffian origin: a case report.

J Surg Case Rep 2022 May 27;2022(5):rjac243. Epub 2022 May 27.

Department of Surgery, General Hospital, Sarajevo 71 000, Bosnia and Herzegovina.

Female adnexal tumors of probable Wolffian origin (FATWOs) are extremely rare tumors, with only around 100 cases published worldwide. FATWOs are most frequently found in the broad ligament, but these can also appear in the mesosalpinx, Fallopian tube, ovary, paravaginal region or peritoneum. We present a case of a 68-year-old female with a history of painless abdominal distension and frequent urination, with palpable big abdominal mass. Read More

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Large Cell Neuroendocrine Carcinoma of the Skin/Conjunctiva: A Series of 6 Cases including 1 Combined Case With Squamous Cell Carcinoma.

Am J Dermatopathol 2022 May 30. Epub 2022 May 30.

Department of Diagnostic Pathology, Shizuoka Cancer Center Hospital, Sunto, Japan.

Abstract: This study sought to reveal the clinicopathologic characteristics of large cell neuroendocrine carcinoma (LCNEC) of the skin/conjunctiva. The retrieved patients included 3 men and 3 women with a median age of 85 (63-95) years. All lesions occurred on the face, including the ears, with a median tumor size of 11. Read More

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Ciliary Gland Adenocarcinoma of the Eyelid Arising in Hidrocystoma: Case Report and Review of Previously Reported Cases.

Am J Dermatopathol 2022 May 30. Epub 2022 May 30.

St. Joseph Dermpath, Houston, TX.

Abstract: Moll gland is a modified tubular-shaped apocrine sweat gland, which is located on the margin of the eyelid. Moll glands are also known as ciliary glands. The function of these glands was not well known for a long time. Read More

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Well-differentiated cerebellum in an ovarian mature cystic teratoma: a case report and review of the literature.

J Med Case Rep 2022 Jun 1;16(1):215. Epub 2022 Jun 1.

Department of Radiology, College of Medicine, King Fahd Hospital of the University, Imam Abdulrahman Bin Faisal University, Post Box No. 1982, Dammam, 31441, Saudi Arabia.

Background: Mature teratoma is the most common germ cell tumor as it represents 95% of germ cell tumors. Although common in children and young adults, ovarian teratoma can occur at any age. Mature teratomas are composed of mature tissues representing elements derived from more than one embryonic germ layer (ectoderm, mesoderm, and endoderm), with ectodermal derivatives being the usual predominant component; however, the finding of a well-differentiated cerebellum is extremely rare. Read More

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Use of Thiazide Diuretics and Risk of All Types of Skin Cancers: An Updated Systematic Review and Meta-Analysis.

Cancers (Basel) 2022 May 23;14(10). Epub 2022 May 23.

Department of Medicine, Division of Nephrology, University of Ottawa, Ottawa, ON K1H 8L6, Canada.

Background: The use of thiazide diuretics is associated with skin cancer risk; however, whether this applies to all skin cancer types is unclear.

Methods: In this meta-analysis, we searched multiple electronic databases and gray literature up to 10 April 2022, with no language restrictions, to identify relevant randomized controlled trials (RCTs) and non-randomized studies (cohort, case-control) that investigated the association between thiazide diuretics and skin cancer. The primary outcomes of interest were malignant melanoma and non-melanoma skin cancer (basal cell carcinoma [BCC], squamous cell carcinoma [SCC]). Read More

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Sebaceous adenoma occurring within an intracranial dermoid cyst.

Neuropathology 2022 May 25. Epub 2022 May 25.

Department of Neurosurgery, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Japan.

Among intracranial cystic lesions, dermoid cysts and epidermoid cysts are relatively common benign tumors. In a small number of these tumors, it is known that squamous cell carcinomas arise in the lining epithelium of the cysts. Among tumors derived from the appendage, only one case of hidradenoma within a dermoid cyst and no cases of sebaceous tumor have been reported previously. Read More

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Testosterone-Secreting Endometrioid Ovarian Carcinoma Presenting With Hyperandrogenism.

AACE Clin Case Rep 2022 May-Jun;8(3):135-138. Epub 2022 Jan 25.

University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, New York.

Background/objective: Epithelial cell ovarian carcinomas rarely secrete steroid hormones, while sex cord and stromal cell ovarian carcinomas often do so. The objective of this report is to describe a patient with endometrioid ovarian carcinoma, an epithelial cell tumor, who presented with hyperandrogenism due to testosterone production by the tumor.

Case Report: A 67-year-old postmenopausal woman with no history of endometriosis presented with new onset of hirsutism. Read More

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January 2022

Ocular adnexal lymphoma: A single-institution retrospective study.

Saudi J Ophthalmol 2021 Jul-Sep;35(3):230-238. Epub 2022 Apr 18.

Department of Pathology, Wills Eye Hospital, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, PA, USA.

Purpose: To characterize demographic, clinical, and histopathologic features of ocular adnexal lymphoma (OAL) at a single institution.

Methods: Retrospective review of all patients with pathologic diagnosis of OAL between 2015 and 2020.

Results: There were 133 patients with OAL, with a median age of 65 years (range 23-97) and a slight female predominance (male: female = 1:1. Read More

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Basal cell carcinosarcoma of the eyelid with osteosarcomatous transformation.

Saudi J Ophthalmol 2021 Jul-Sep;35(3):257-260. Epub 2021 Nov 17.

Department of Ophthalmology and Visual Sciences, Dalhousie University, Halifax, Nova Scotia, Canada.

A carcinosarcoma is a neoplasm with malignant epithelial and mesenchymal components. It is thought to arise by mesenchymal transformation of the epithelial elements. The cutaneous form of carcinosarcoma is rare and is associated with sun exposure; most cases arise in the head and neck. Read More

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November 2021

Oncocytic lesions of the ocular adnexa: A review of the histopathology with a brief discussion of the pathogenesis.

Saudi J Ophthalmol 2021 Jul-Sep;35(3):179-185. Epub 2022 Apr 18.

Eye Associates of New Mexico, Albuquerque, NM, USA.

Oncocytic lesions may be metaplastic, hyperplastic, or neoplastic and occur in a variety of tissues, including those of the ocular adnexa. Oncocytes are enlarged epithelial cells with abundant eosinophilic granules in the cytoplasm, which represent large mitochondria with distorted cristae. The causes of oncocytic lesions remain uncertain, although in some sites such as the lacrimal sac, chronic inflammation may be a factor. Read More

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Xanthogranulomatous salpingo-oophoritis presenting as an ovarian tumour.

BMJ Case Rep 2022 May 19;15(5). Epub 2022 May 19.

Gynecology, Centro Hospitalar de Vila Nova de Gaia Espinho EPE, Vila Nova de Gaia, Portugal.

Xanthogranulomatous salpingo-oophoritis (XGSO) is an exceptionally rare entity. Its clinical manifestations and imaging modalities can mimic benign and malignant adnexal diseases, making it difficult to diagnose. Here we report a case of XGSO in a young woman who was operated with suspicion of a borderline ovarian tumour. Read More

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Metastatic follicular carcinoma arising from struma ovarii.

BMJ Case Rep 2022 May 17;15(5). Epub 2022 May 17.

Obstetrics & Gynaecology, Gynaecological Oncology, KK Women's and Children's Hospital, Singapore.

Struma ovarii (SO) is an uncommon monodermal teratoma predominantly composed of mature thyroid tissue. Approximately 5% of SO are malignant; however, metastases are rare. A single female in her 40s, with a medical history of Graves' disease and bilateral cystectomy 10 years prior for right endometriotic cyst and left SO, presented with an enlarging abdominal mass for 4 months. Read More

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Rare malignant adnexal tumour of the skin involving distal phalanx of right thumb with co-existing primary lung cancer in a 72-year-old patient: A case report.

Int J Surg Case Rep 2022 Jun 10;95:107174. Epub 2022 May 10.

Department of General Surgery, Mata Chanan Devi Hospital, New Delhi, India.

Introduction And Importance: Malignant adnexal tumours of the skin are a group of rare malignancies. These tumours can further differentiate into eccrine, apocrine, sebaceous, sweat duct, or ceruminous glands within the skin or follicular cells. Sebaceous carcinoma, a malignant adnexal tumour of the skin, is a rare and malignant tumour of the sebaceous glands. Read More

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Risk and Lag-time for Development of Lacrimal Gland Carcinoma Expleomorphic Adenoma: Observations and Conjectural Study.

Ophthalmic Plast Reconstr Surg 2022 May 13. Epub 2022 May 13.

Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom.

Aims: To estimate the proportion of de novo lacrimal gland pleomorphic adenomas (PAs) and carcinomas expleomorphic adenomas (CEPAs), together with age at presentation and first symptom. Conjectural models of tumor growth are considered.

Methods: Retrospective review of patients with orbital lobe PA or CEPA. Read More

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Dermoscopy of cutaneous adnexal tumours: a systematic review of the literature.

J Eur Acad Dermatol Venereol 2022 May 10. Epub 2022 May 10.

Centro Oncologico ad Alta Tecnologia Diagnostica, Azienda Unità Sanitaria Locale - IRCCS di Reggio Emilia, Reggio Emilia, Italy.

Cutaneous adnexal tumours (ATs) encompass a variegated group of hamartomas and benign or malignant tumours, originating from the hair follicle, sebaceous, eccrine or apocrine glands that may simulate other cutaneous neoplasms. This study aims to provide a comprehensive overview of the spectrum of clinical and dermoscopic features of ATs, to better define these lesions and assist in the differential diagnosis. We performed a two-step systematic search of the literature in PubMed, Embase and Cochrane Library databases from inception until 4 September 2020. Read More

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