Am J Dermatopathol 2021 May 11. Epub 2021 May 11.
Department of Dermatology, Oregon Health and Science University, Portland, OR; J. Chung's work was performed while at Thomas Jefferson University Hospital, Philadelphia, PA; and Departments of Pathology, Anatomy, and Cell Biology, and Dermatology and Cutaneous Biology, Thomas Jefferson University Hospital, Philadelphia, PA.
Background: The transcription factor p63 is a homolog of p53, expressed in basal layers of epithelia and myoepithelial cells. Some studies have suggested that p63 may provide utility in differentiating primary versus metastatic mucinous carcinoma of the skin, given its preferential expression in primary adnexal neoplasms. There have been few studies investigating the expression patterns of p40, an isoform of p63, in primary cutaneous mucinous carcinomas. Read More