60,301 results match your criteria Administrative Eyecare[Journal]


Stereoisomer-specific occurrence, distribution, and fate of chiral brominated flame retardants in different wastewater treatment systems in Hong Kong.

J Hazard Mater 2019 Apr 13;374:211-218. Epub 2019 Apr 13.

State Key Laboratory of Marine Pollution (SKLMP), Research Centre for the Oceans and Human Health, Shenzhen Key Laboratory for the Sustainable Use of Marine Biodiversity, City University of Hong Kong, Hong Kong Special Administrative Region, China; Department of Chemistry, City University of Hong Kong, Hong Kong Special Administrative Region, China. Electronic address:

This study investigated the occurrence and fate of 1,2,5,6,9,10-hexabromocyclododecane (HBCD) and 1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane (TBECH), two chiral brominated flame retardants (BFRs) with sixteen different stereoisomers, in four Hong Kong wastewater treatment plants (WWTPs) featuring diverse treatment processes during a two-year sampling campaign. More effective HBCD removal was achieved via biodegradation as compared to sludge sorption, whereas both chemically enhanced primary treatment and secondary treatment yielded high TBECH elimination (>90%). α-HBCD (54-75%) predominated in all samples, and its proportions were increased in effluent as compared to influent and sludge. Read More

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http://dx.doi.org/10.1016/j.jhazmat.2019.04.041DOI Listing

Respiratory virus infection amongst hospitalized adult patients with or without clinically-apparent respiratory infection: a prospective cohort study.

Clin Microbiol Infect 2019 Apr 17. Epub 2019 Apr 17.

Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China; Department of Clinical Microbiology and Infection Control, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China; Department of Microbiology, Queen Mary Hospital, Pokfulam, Hong Kong Special Administrative Region, China; State Key Laboratory for Emerging Infectious Diseases, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China; Carol Yu Centre for Infection, The University of Hong Kong, Hong Kong Special Administrative Region, China. Electronic address:

Objectives: We aimed to determine the viral epidemiology and clinical characteristics of patients with and those without clinically-apparent respiratory tract infection.

Methods: This prospective cohort study was conducted during the 2018 winter influenza season. Adult patients with fever/respiratory symptoms (fever/RS group) were age- and sex-matched with patients without fever/respiratory symptoms (non-fever/RS group) in a 1:1 ratio. Read More

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http://dx.doi.org/10.1016/j.cmi.2019.04.012DOI Listing

Bartonella diversity and zoonotic potential in indigenous Tete Veld rats (Aethomys ineptus) from South Africa.

Infect Genet Evol 2019 Apr 17. Epub 2019 Apr 17.

Mammal Research Institute (MRI), Department of Zoology and Entomology, University of Pretoria, Private Bag 20, Hatfield 0028, South Africa. Electronic address:

Bartonellosis is a vector-borne disease that is often misdiagnosed due to a broad range of clinical symptoms, compounded by a lack of awareness regarding the prevalence, diversity and public health impacts of regional strains. Despite recent PCR-based confirmation of Bartonella in 9.7% of non-malarial, acute febrile patients in South Africa, data regarding reservoirs of infection are limited. Read More

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http://dx.doi.org/10.1016/j.meegid.2019.04.012DOI Listing

Lifestyle Behavior and Mental Health in Early Adolescence.

Pediatrics 2019 Apr 19. Epub 2019 Apr 19.

Population Health Intervention Research Unit, School of Public Health, Edmonton, University of Alberta, Edmonton, Canada;

Background And Objectives: Mental illnesses affect >15% of Canadian adolescents. New preventive strategies are critically needed. We examined the associations of meeting established recommendations for diet, physical activity, sleep, and sedentary behavior in childhood with mental illness in adolescence. Read More

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http://pediatrics.aappublications.org/lookup/doi/10.1542/ped
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http://dx.doi.org/10.1542/peds.2018-3307DOI Listing
April 2019
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Emergence of human infection with Jingmen tick virus in China: A retrospective study.

EBioMedicine 2019 Apr 16. Epub 2019 Apr 16.

State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, PR China. Electronic address:

Background: A tick-borne segmented RNA virus called Jingmen tick virus (JMTV) was recently identified, variants of which were detected in a non-human primate host and fatal patients with Crimean-Congo haemorrhagic fever. We investigated its infectivity and pathogenicity for humans.

Methods: We obtained skin-biopsy, blood and serum samples from patients with tick bites, and used high-throughput sequencing, in situ hybridisation, and serologic testing to diagnose and ascertain the cases of JMTV infection. Read More

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http://dx.doi.org/10.1016/j.ebiom.2019.04.004DOI Listing

Food and Drug Administration labeling and medication guides: A health outcomes critique.

Res Social Adm Pharm 2019 Apr 11. Epub 2019 Apr 11.

Social & Administrative Sciences Division at the University of Wisconsin - Madison, School of Pharmacy, Madison, United States. Electronic address:

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http://dx.doi.org/10.1016/j.sapharm.2019.04.007DOI Listing
April 2019
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Flexicaulin A, An -Kaurane Diterpenoid, Activates p21 and Inhibits the Proliferation of Colorectal Carcinoma Cells through a Non-Apoptotic Mechanism.

Int J Mol Sci 2019 Apr 18;20(8). Epub 2019 Apr 18.

School of Chinese Medicine, Hong Kong Baptist University, Kowloon, Hong Kong SAR, China.

Natural products, explicitly medicinal plants, are an important source of inspiration of antitumor drugs, because they contain astounding amounts of small molecules that possess diversifying chemical entities. For instance, (formerly ), a genus of the Lamiaceae (formerly Labiatae) family, has been reported as a rich source of natural diterpenes. In the current study, we evaluated the in vitro anti-proliferative property of flexicaulin A (FA), an diterpenoid with an -kaurane structure, in human carcinoma cells, by means of cell viability assay, flow cytometric assessment, quantitative polymerase chain reaction array, Western blotting analysis, and staining experiments. Read More

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https://www.mdpi.com/1422-0067/20/8/1917
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http://dx.doi.org/10.3390/ijms20081917DOI Listing
April 2019
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Genetic variation in starch physicochemical properties of Chinese foxtail millet (Setaria italica Beauv.).

Int J Biol Macromol 2019 Apr 16. Epub 2019 Apr 16.

Department of Food Science and Technology, Shanghai Jiao Tong University, Shanghai 200240, People's Republic of China. Electronic address:

In this study, 34 Chinese foxtail millet germplasm accessions (cultivars and breeding lines) were characterized for starch physicochemical properties including apparent amylose content, and gel textural, RVA pasting, thermal and retrogradation properties. The relationships among 21 starch parameters were discussed based on correlation analysis and hierarchical cluster analysis. Generally, this set of germplasm presented a surprisingly low genetic diversity in starch properties. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01418130193110
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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.022DOI Listing
April 2019
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Novel Measures of Benzodiazepine and Z-Drug Utilisation Trends in a Canadian Provincial Adult Population (2001-2016).

J Popul Ther Clin Pharmacol 2019 Jan 22;26(1):e22-e38. Epub 2019 Jan 22.

College of Pharmacy, University of Manitoba.

Purpose:  1) To evaluate trends for benzodiazepines (BZD) and Z-Drugs over 15-years in a general Canadian adult population measured by: a) consumption b) pharmacologic exposure c) dose intensity and d) prevalence of use. 2) To demonstrate the utility of Diazepam Milligram Equivalence (DME) based measurements when used in conjunction with traditional standard measurements of drug utilization such as the Defined Daily Dose (DDD) system.

Methods: Administrative data covering all prescriptions from April 2001-March 2016 for BZD and Z-Drugs for patients ≥18 years was used. Read More

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http://www.jptcp.com/index.php/jptcp/article/view/52
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http://dx.doi.org/10.22374/1710-6222.26.1.3DOI Listing
January 2019
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Comparison of a Potential Hospital Quality Metric With Existing Metrics for Surgical Quality-Associated Readmission.

JAMA Netw Open 2019 Apr 5;2(4):e191313. Epub 2019 Apr 5.

Veterans Affairs, Palo Alto, Veterans Affairs Medical Center, Palo Alto, California.

Importance: The existing readmission quality metric does not meaningfully distinguish readmissions associated with surgical quality from those that are not associated with surgical quality and thus may not reflect the quality of surgical care.

Objective: To compare a quality metric that classifies readmissions associated with surgical quality with the existing metric of any unplanned readmission in a surgical population.

Design, Setting, And Participants: Cohort study using US nationwide administrative data collected on 4 high-volume surgical procedures performed at 103 Veterans Affairs hospitals from October 1, 2007, through September 30, 2014. Read More

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http://dx.doi.org/10.1001/jamanetworkopen.2019.1313DOI Listing

The qualculative dimension of healthcare data interoperability.

Authors:
Kathleen H Pine

Health Informatics J 2019 Apr 19:1460458219833095. Epub 2019 Apr 19.

Arizona State University, USA.

Research on interoperability and information exchange between information technology systems touts the use of secondary data for a variety of purposes, including research, management, quality improvement, and accountability. However, many studies have pointed out that this is difficult to achieve in practice. Hence, this article aims to examine the causes for this by reporting an ethnographic study of the data work performed by medical records coders and birth certificate clerks working in a hospital system to uncover the practices of creating administrative data (e. Read More

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http://journals.sagepub.com/doi/10.1177/1460458219833095
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http://dx.doi.org/10.1177/1460458219833095DOI Listing
April 2019
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Field Testing Integrated Interventions for Schistosomiasis Elimination in the People's Republic of China: Outcomes of a Multifactorial Cluster-Randomized Controlled Trial.

Front Immunol 2019 3;10:645. Epub 2019 Apr 3.

Molecular Parasitology Laboratory, Infectious Diseases Division, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.

Despite significant progress, China faces the challenge of re-emerging schistosomiasis transmission in currently controlled areas due, in part, to the presence of a range of animal reservoirs, notably water buffalo and cattle, which can harbor infections. Environmental, ecological and social-demographic changes in China, shown to affect the distribution of oncomelanid snails, can also impact future schistosomiasis transmission. In light of their importance in the , lifecycle, vaccination has been proposed as a means to reduce the excretion of egg from cattle and buffalo, thereby interrupting transmission from these reservoir hosts to snails. Read More

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http://dx.doi.org/10.3389/fimmu.2019.00645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456715PMC
April 2019
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Measuring social, environmental and health inequalities using deep learning and street imagery.

Sci Rep 2019 Apr 18;9(1):6229. Epub 2019 Apr 18.

School of Public Health, Imperial College London, London, UK.

Cities are home to an increasing majority of the world's population. Currently, it is difficult to track social, economic, environmental and health outcomes in cities with high spatial and temporal resolution, needed to evaluate policies regarding urban inequalities. We applied a deep learning approach to street images for measuring spatial distributions of income, education, unemployment, housing, living environment, health and crime. Read More

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http://www.nature.com/articles/s41598-019-42036-w
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http://dx.doi.org/10.1038/s41598-019-42036-wDOI Listing
April 2019
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Costs of implementing and sustaining enhanced collaborative care programs involving community partners.

Implement Sci 2019 Apr 18;14(1):37. Epub 2019 Apr 18.

Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Box 356560, Seattle, WA, 98195-6560, USA.

Background: Collaborative care is an evidence-based program for treating depression in primary care. We sought to expand this model by recruiting clinics interested in incorporating community partners (i.e. Read More

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http://dx.doi.org/10.1186/s13012-019-0882-6DOI Listing

Tuberculosis care for migrant patients in Portugal: a mixed methods study with primary healthcare providers.

BMC Health Serv Res 2019 Apr 18;19(1):233. Epub 2019 Apr 18.

Global Health and Tropical Medicine, GHTM, Instituto de Higiene e Medicina Tropical, IHMT, Universidade Nova de Lisboa, UNL, Rua da Junqueira 100, 1349-008, Lisbon, Portugal.

Background: Tuberculosis (TB) is still a major global health problem. The increasing number of cases observed among foreign-born populations contrasts with the decreasing trends observed in later years in some high-income countries. Healthcare providers are key interveners in the control of TB and HIV-TB infections. Read More

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http://dx.doi.org/10.1186/s12913-019-4050-0DOI Listing

The impact of the adoption of a patient rostering model on primary care access and continuity of care in urban family practices in Ontario, Canada.

BMC Fam Pract 2019 Apr 18;20(1):52. Epub 2019 Apr 18.

Department of Public Health Sciences, Queen's University, 62 Fifth Field Company Lane, Kingston, ON, K7L 3N6, Canada.

Background: Greater continuity and access to primary care results in improved patient health, satisfaction, and reduced healthcare costs. Although patient rostering is considered to be a cornerstone of a high performing primary care system and is believed to improve continuity and access, few studies have examined these relationships. This study examined the impact of the adoption of a patient rostering enhanced fee-for-service model (eFFS) on continuity, coordination of specialized care, and access. Read More

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http://dx.doi.org/10.1186/s12875-019-0942-7DOI Listing

Comparison of the accuracy of classification models to estimate healthcare use and costs associated with COPD exacerbations in Saskatchewan, Canada: A retrospective cohort study.

Can J Respir Ther 2017 1;53(3):37-44. Epub 2017 Aug 1.

Department of Community Health Sciences, University of Manitoba, Winnipeg, MB, Canada.

Objective: COPD is a high-cost disease and results in frequent contacts with the healthcare system. The study objective was to compare the accuracy of classification models with different covariates for classifying COPD patients into cost groups.

Methods: Linked health administrative databases from Saskatchewan, Canada, were used to identify a cohort of newly diagnosed COPD patients (April 1, 2007 to March 31, 2011) and their episodes of healthcare encounters for disease exacerbations. Read More

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Does an assessment aid improve Glasgow Coma Scale scoring by helicopter rescuers in Hong Kong: A randomised controlled trial.

Australas Emerg Care 2018 Aug 25;21(3):105-110. Epub 2018 Jun 25.

Accident and Emergency Medicine Academic Unit, Chinese University of Hong Kong, Hong Kong Special Administrative Region.

Background: Glasgow Coma Scale (GCS) is one of the most commonly used patient assessment tools. This study aimed to determine whether an assessment aid can improve the GCS scoring accuracy by helicopter rescuers in Hong Kong.

Methods: In this randomised controlled trial, Air Crewman Officers (ACMOs) of Government Flying Service in Hong Kong were randomised into two groups, with and without assessment aid. Read More

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http://dx.doi.org/10.1016/j.auec.2018.06.001DOI Listing

Night work during pregnancy and preterm birth-A large register-based cohort study.

PLoS One 2019 18;14(4):e0215748. Epub 2019 Apr 18.

Department of Occupational and Environmental Medicine, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.

Background: Melatonin stimulates the production of progesterone, which is essential for the maintenance of pregnancy. Since melatonin in blood is reduced due to work under illuminated conditions during night work, it has been hypothesized that night work may increase the risk of preterm birth. Previous meta-analyses have not revealed increased risk of preterm birth in women working night shifts during pregnancy. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215748PLOS
April 2019
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Conscience and Religious Freedom Division Marks Its First Anniversary with Action.

Authors:
Sandra H Johnson

Hastings Cent Rep 2019 Mar;49(2):4-5

In January 2018, the Trump administration established the Conscience and Religious Freedom Division within the Department of Health and Human Services' Office of Civil Rights with the explicit goal of intensifying legal protection of religious and conscience objections in health care. The establishment of OCR's new division illustrates the significant powers of administrative agencies to mold the substance of law without seeking legislative action. The mere formation of a division dedicated to protecting conscience rights is already having a significant impact; it is causing health care entities, including hospitals, research organizations, and clinics, to change policies and practices to comply with the declared enforcement strategy. Read More

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http://doi.wiley.com/10.1002/hast.986
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http://dx.doi.org/10.1002/hast.986DOI Listing
March 2019
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The p.P479L variant in CPT1A is associated with infectious disease in a BC First Nation.

Paediatr Child Health 2019 May 6;24(2):e111-e115. Epub 2018 Aug 6.

Department of Pathology and Laboratory Medicine, BC Children's Hospital, University of British Columbia, Vancouver, British Columbia.

Background: The hepatic carnitine palmitoyltransferase I () p.P479L variant is common in Aboriginal populations across coastal British Columbia, Alaska, the Canadian North, and Greenland. While the high frequency of this variant suggests positive selection, other studies have shown an association with sudden unexpected death in infancy and infection. Read More

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https://academic.oup.com/pch/article/24/2/e111/5067175
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http://dx.doi.org/10.1093/pch/pxy106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462176PMC
May 2019
1 Read

Physical inactivity, cardiometabolic disease, and risk of dementia: an individual-participant meta-analysis.

BMJ 2019 04 17;365:l1495. Epub 2019 Apr 17.

Biomedicum, Faculty of Medicine, University of Helsinki, Helsinki, Finland.

Objective: To examine whether physical inactivity is a risk factor for dementia, with attention to the role of cardiometabolic disease in this association and reverse causation bias that arises from changes in physical activity in the preclinical (prodromal) phase of dementia.

Design: Meta-analysis of 19 prospective observational cohort studies.

Data Sources: The Individual-Participant-Data Meta-analysis in Working Populations Consortium, the Inter-University Consortium for Political and Social Research, and the UK Data Service, including a total of 19 of a potential 9741 studies. Read More

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http://www.bmj.com/lookup/doi/10.1136/bmj.l1495
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http://dx.doi.org/10.1136/bmj.l1495DOI Listing
April 2019
3 Reads

Incident haemodialysis and outcomes in the Top End of Australia.

Aust Health Rev 2019 Apr 18. Epub 2019 Apr 18.

The Northern Territory has the highest incidence of haemodialysis care for end-stage kidney disease in Australia. Although acute kidney injury (AKI) is a recognised risk for chronic kidney disease (CKD), the effect of AKI causing incident haemodialysis (iHD) is unknown. Audits identifying antecedents of iHD may inform health service planning. Read More

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http://www.publish.csiro.au/?paper=AH18230
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http://dx.doi.org/10.1071/AH18230DOI Listing
April 2019
2 Reads

Association between emergency department length of stay and adverse perioperative outcomes in emergency surgery: a cohort study in two Colombian University hospitals.

BMC Emerg Med 2019 Apr 17;19(1):27. Epub 2019 Apr 17.

Grupo de Cardiología Preventiva, Facultad de Ciencias de la Salud, Universidad Autónoma de Bucaramanga, Bucaramanga, Colombia.

Background: In low- and middle-income countries emergency surgery represents a higher proportion of the total number of surgeries and is associated with greater morbidity/mortality. Study aims were to determine if emergency department length of stay (ED-LOS) was associated with adverse perioperative outcomes and if such association varied across patient's risk categories.

Methods: A retrospective cohort study was conducted of adult patients who underwent orthopedic or abdominal emergency surgery at two Colombian University hospitals. Read More

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https://bmcemergmed.biomedcentral.com/articles/10.1186/s1287
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http://dx.doi.org/10.1186/s12873-019-0241-6DOI Listing
April 2019
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Spatiotemporal patterns of AIDS incidence among adults in São Paulo, Brazil.

Rev Soc Bras Med Trop 2019 Apr 11;52:e20180020. Epub 2019 Apr 11.

Departamento de Medicina Social, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brasil.

Introduction: AIDS remains a major public health concern in Brazil.

Methods: This study investigated spatiotemporal patterns of reported AIDS cases among adults in São Paulo between 2000 and 2016, and their associations with human development index.

Results: In the early 20th century, the more developed administrative districts (ADs) indicated higher AIDS incidences among men. Read More

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S
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http://dx.doi.org/10.1590/0037-8682-0020-2018DOI Listing
April 2019
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A retrospective cohort study comparing non-fatal self-harm emergency department visits between Canadian veterans living in Ontario and matched civilians.

Int Rev Psychiatry 2019 Apr 17:1-9. Epub 2019 Apr 17.

d IC/ES , Toronto , Canada.

This was a retrospective cohort study linking provincial administrative databases to compare rates of non-fatal self-harm between CAF and RCMP veterans living in Ontario and age-matched civilians. This study included male veterans who registered for provincial health insurance between 2002 and 2013. A civilian comparator group was matched 4:1 on age and sex. Read More

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http://dx.doi.org/10.1080/09540261.2019.1580685DOI Listing

Health sector decentralisation in Tanzania: Analysis of decision space in human resources for health management.

Int J Health Plann Manage 2019 Apr 17. Epub 2019 Apr 17.

Institute of Development Studies, University of Dar es Salaam, Dar es Salaam, Tanzania.

While decentralisation of health systems has dominated the political arena in the low- and middle-income countries since the 1970s, many studies on decentralisation have focused on understanding who is given more decision-making authority, but less attention is paid to understanding what that authority involves. This paper assesses the range of decision-making authority transferred from the central government to subnational levels in the area of human resources for health management in Tanzania. This analysis was guided by the decision space framework and relied on interviews, focused group discussions, and analysis of documents. Read More

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http://dx.doi.org/10.1002/hpm.2792DOI Listing

Performance of care for end-of-life cancer patients in Tuscany: The interplay between place of care, aggressive treatments, opioids, and place of death. A retrospective cohort study.

Int J Health Plann Manage 2019 Apr 17. Epub 2019 Apr 17.

Scuola Superiore Sant'Anna, Institute of Management and Department EMbeDS, Pisa, Italy.

Supportive and palliative care at the end of life (EOL) is a core component of health systems. Providing care at the EOL may require the interaction of several care providers working in different settings including nursing homes, home care, hospices, and hospitals. This work aims to (a) provide evidence on the performance of EOL care for cancer patients across healthcare organizations, with a focus on the place of care, aggressive treatments, opioids, and the place of death and (b) analyze factors associated with dying in hospital. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/hpm.2789
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http://dx.doi.org/10.1002/hpm.2789DOI Listing
April 2019
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Factors associated with misreporting in performance-based financing in Burkina Faso: Implications for risk-based verification.

Int J Health Plann Manage 2019 Apr 17. Epub 2019 Apr 17.

Heidelberg Institute of Global Health, University Hospital and Faculty of Medicine, Heidelberg University, Germany.

Performance-based financing (PBF) has been piloted in many low- and middle-income countries (LMICs) as a strategy to improve access to and quality of health services. As a key component of PBF, quantity verification is carried out to ensure that reported data matches the actual number of services provided. However, cost concerns have led to a call for risk-based verification. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/hpm.2786
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http://dx.doi.org/10.1002/hpm.2786DOI Listing
April 2019
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Care quality for rheumatoid arthritis patients in Quebec.

Int J Rheum Dis 2019 Apr 16. Epub 2019 Apr 16.

Division of Clinical Epidemiology, Research Institute of the McGill University Health Center, Montreal, Quebec, Canada.

Aim: The aims of this study were to: (a) measure the proportion of CARTaGENE rheumatoid arthritis (RA) patients fulfilling pre-specified quality indicators (ie disease-modifying antirheumatic drug [DMARD] use, regular follow up, use of folate supplementation, use of vitamin D and calcium, exercise and smoking status); and (b) examine variation in DMARD use with respect to patient age, sex, education and income.

Methods: A cohort of RA patients was constructed based on the CARTaGENE survey and health administrative database. CARTaGENE is a large, established, population-based study which recruited 19 995 participants from four metropolitan regions in Quebec. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/1756-185X.13
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http://dx.doi.org/10.1111/1756-185X.13580DOI Listing
April 2019
3 Reads

Savouring and psychological well-being in family dyads coping with cancer: An actor-partner interdependence model.

Eur J Cancer Care (Engl) 2019 Apr 16:e13047. Epub 2019 Apr 16.

Teachers College, Columbia University, New York, New York.

Previous studies have investigated interdependence of the associations between predictors and negative psychological outcomes in dyads of cancer patients and family caregivers. This study examined the dyadic effects of perceived capability of savouring the moment on psychological well-being. A total of 152 dyads of cancer patients and caregivers reported their perceived capability of savouring the moment (Savoring Beliefs Inventory), state positive affect (Chinese Affect Scale) and life satisfaction (Satisfaction With Life Scale) within 6 months following diagnosis. Read More

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http://dx.doi.org/10.1111/ecc.13047DOI Listing

Prior Authorization Policies and Preferred Drug Lists in Medicaid Plans: Stakeholder Perspectives on the Implications for Youth with ADHD.

Adm Policy Ment Health 2019 Apr 16. Epub 2019 Apr 16.

Department of Health Policy & Management, Rollins School of Public Health, Emory University, 1518 Clifton Road, NE, Atlanta, GA, 30322, USA.

This qualitative study describes how Medicaid policies create challenges for the delivery and receipt of mental health treatment for low-income youth in Georgia. We conducted focus groups with caregivers of Medicaid-enrolled children with ADHD and semi-structured interviews with providers and administrators at four safety net clinics that provided mental health care to these youth. Stakeholders reported that prior authorization policies for psychosocial services, restrictiveness of preferred drug lists, and changes in preferred drug lists in Medicaid plans created barriers to treatment continuity and quality for youth with ADHD and led to more administrative burden for safety-net clinics serving these youth. Read More

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http://dx.doi.org/10.1007/s10488-019-00937-yDOI Listing

An assessment of emergency department information systems based on the HL7 functional profile.

J Educ Health Promot 2019 15;8:26. Epub 2019 Feb 15.

Department of Information Technology, Isfahan University of Medical Sciences, Isfahan, Iran.

Context: Emergency Department Information System (EDIS) plays a significant role in supporting the emergency department (ED) workflow. Hence, it is vital to assess the services provided by this system in order to identify its strengths and weaknesses.

Aims: The study aimed to assess the information systems in use in the ED of 11 teaching hospitals associated with Isfahan University of Medical Sciences (IUMS) so as to identify their strengths and weaknesses and improving the quality of these systems. Read More

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http://dx.doi.org/10.4103/jehp.jehp_64_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6432815PMC
February 2019
1 Read

Race and socioeconomic disparity in treatment and outcome of traumatic cervical spinal cord injury with fracture: Nationwide Inpatient Sample database, 1998-2009.

Spinal Cord 2019 Apr 16. Epub 2019 Apr 16.

University of Florida, Lillian S. Wells Department of Neurosurgery, Gainesville, FL, USA.

Study Design: A retrospective national administrative database study.

Objective: Advances in treatment of traumatic cervical spinal cord injury with fracture (TCSCIF) have led to significant improvements in clinical outcomes; however, progress in healthcare is seldom ubiquitous across demographic groups. Therefore, we explored if disparities in treatment and outcome after TCSCIF exist across race and socioeconomic status. Read More

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http://dx.doi.org/10.1038/s41393-019-0280-6DOI Listing

Persistence with opioids post discharge from hospitalisation for surgery in Australian adults: a retrospective cohort study.

BMJ Open 2019 Apr 16;9(4):e023990. Epub 2019 Apr 16.

Quality Use of Medicines and Pharmacy Research Centre, University of South Australia Division of Health Sciences, Adelaide, South Australia, Australia.

Objective: To determine time to opioid cessation post discharge from hospital in persons who had been admitted to hospital for a surgical procedure and were previously naïve to opioids.

Design, Setting And Participants: Retrospective cohort study using administrative health claims database from the Australian Government Department of Veterans' Affairs (DVA). DVA gold card holders aged between 18 and 100 years who were admitted to hospital for a surgical admission between 1 January 2014 and 30 December 2015 and naïve to opioid therapy prior to admission were included in the study. Read More

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http://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2018-02399
Publisher Site
http://dx.doi.org/10.1136/bmjopen-2018-023990DOI Listing
April 2019
1 Read

Integrated Printed Microfluidic Biosensors.

Trends Biotechnol 2019 Apr 13. Epub 2019 Apr 13.

Biosensors and Bioelectronics Centre, Department of Physics, Chemistry and Biology (IFM), Linköping University, 58183, Linköping, Sweden. Electronic address:

Integrated printed microfluidic biosensors are one of the most recent point-of-care (POC) sensor developments. Fast turnaround time for production and ease of customization, enabled by the integration of recognition elements and transducers, are key for on-site biosensing for both healthcare and industry and for speeding up translation to real-life applications. Here, we provide an overview of recent progress in printed microfluidics, from the 2D to the 4D level, accompanied by novel sensing element integration. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01677799193005
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http://dx.doi.org/10.1016/j.tibtech.2019.03.009DOI Listing
April 2019
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Population-based cohort study of the correlation between provision of care and the risk for complications after appendectomy in children.

J Pediatr Surg 2019 Mar 28. Epub 2019 Mar 28.

Department of Pediatric Surgery, Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden; Departments of Women's and Children's Health, Stockholm, Sweden.

Purpose: To investigate the impact of hospital administrative level and caseload of pediatric appendectomies on the morbidity and mortality after appendectomy in a population-based cohort of Swedish children.

Methods: Population-based cohort study including all Swedish children less than 15 years of age that underwent appendectomy for suspected appendicitis, 1987-2009. Patient characteristics and data on postoperative morbidity and mortality were collected from the Swedish National Patient Register and the Swedish Death Register. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2019.03.013DOI Listing

Justice or Injustice: a History and Critique of the New York State Justice Center for the Protection of People with Special Needs.

Albany Law Rev 2017;80(3):1181-225

Albany Law School.

The creation of the New York State Justice Center for the Protection of People with Special Needs ("Justice Center") was announced with great fanfare in 2013. Its goal is laudable: strengthening and standardizing "the safety net for vulnerable persons, adults and children alike, who are receiving care from New York's human service agencies and programs." Its jurisdiction is broad: covering residential and non-residential programs and provider agencies that come within the purview of six state oversight agencies, namely, the Office of Mental Health, the Office for People with Developmental Disabilities, the Office of Alcohol and Substance Abuse Services, the Office of Children and Family Services, the Department of Health, and the State Education Department. Read More

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January 2017

Cost Savings from a Navigator Intervention for Repeat Detoxification Clients.

J Ment Health Policy Econ 2019 Mar;22(1):3-13

Brandeis University, 415 South Street, MS 035, Waltham, MA, 02453, USA,

Background: Many clients with substance use disorders (SUD) have multiple admissions to a 24-hour level of care for detoxification without ever progressing to SUD treatment. In the US, health insurers have become concerned about the high costs and ineffective results of repeat detox admissions. For other diseases, health systems increasingly target high-risk, high-cost patients with individually tailored interventions delivered by `navigators' who help patients negotiate the complex health care system. Read More

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March 2019
2 Reads

Biofilm research within irrigation water distribution systems: Trends, knowledge gaps, and future perspectives.

Sci Total Environ 2019 Apr 8;673:254-265. Epub 2019 Apr 8.

The School of Biological Sciences, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region; The University of Hong Kong Shenzhen Institute of Research and Innovation (HKU-SIRI), Shenzhen, Guangdong Province, People's Republic of China. Electronic address:

Biofilms in irrigation water distribution systems (IWDSs) play an essential role in spreading pathogens, chemical pollutants, and environmental pollutants into downstream irrigated crops and thus should be considered a potential threat to food safety. Although the role of biofilms in drinking water distribution systems has been extensively studied in the last decade, the research on IWDS biofilms in this period has been limited. This review identifies research gaps in the field of IWDS biofilms, provides perspectives on experimental designs for investigating IWDS biofilms, and suggests potential strategies worth pursuing in IWDS management. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2019.03.464DOI Listing

Immediate effects of coloured overlays on the reading performance of preschool children with an autism spectrum disorder using eye tracking.

Res Dev Disabil 2019 Apr 13;89:141-148. Epub 2019 Apr 13.

School of Medical and Health Sciences, Tung Wah College, Hong Kong Special Administrative Region.

Background: Coloured overlays have often been used to improve reading performance in preschool children with an autism spectrum disorder (ASD), however, previous evidence shows conflicts in its application.

Aims: To investigate the immediate effects of coloured overlays on reading performance using eye tracking in preschool children with ASD and their typical development (TD) counterparts closely matched by chronological age.

Methods: Forty participants with ASD (n = 20) or TD (n = 20) were recruited by convenience sampling and asked to read aloud numbers randomly arranged on paper. Read More

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http://dx.doi.org/10.1016/j.ridd.2019.03.012DOI Listing
April 2019
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Inter-brand competition in the convenience store industry, store density and healthcare utilization.

J Health Econ 2019 Mar 25;65:117-132. Epub 2019 Mar 25.

College of Business and Economics, Lehigh University, Bethlehem, United States; National Bureau of Economic Research, Cambridge, United States. Electronic address:

We investigate the impact of access to convenience stores and competition between convenience store chains on the use of medical care in Taiwan. Using insurance claims from 0.85 million individuals and administrative data on store sales, we find that greater store density and more inter-brand competition reduced expenditures on outpatient medical services and prescription drugs. Read More

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http://dx.doi.org/10.1016/j.jhealeco.2019.03.001DOI Listing

Effects of microcystin-LR on the immune dysfunction and ultrastructure of hepatopancreas in giant freshwater prawn Macrobrachium rosenbergii.

Fish Shellfish Immunol 2019 Apr 13;89:586-594. Epub 2019 Apr 13.

College of Animal Science and Technology, Yangzhou University, Yangzhou, 225009, China. Electronic address:

Microcystins (MCs), produced by cyanobacteria, can strongly inhibit the activity of protein phosphatase, and exhibit strong hepatotoxicity. Macrobrachium rosenbergii is an important aquaculture economic species. Cyanobacterial blooms occur frequently during the culture of M. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10504648193027
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http://dx.doi.org/10.1016/j.fsi.2019.04.039DOI Listing
April 2019
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2.674 Impact Factor

Subsidizing Health Insurance for Low-Income Adults: Evidence from Massachusetts.

Am Econ Rev 2019 Apr;109(4):1530-67

Harvard Kennedy School, Cambridge, MA 02138.

How much are low- income individuals willing to pay for health insurance, and what are the implications for insurance markets? Using administrative data from Massachusetts’ subsidized insurance exchange, we exploit discontinuities in the subsidy schedule to estimate willingness to pay and costs of insurance among low- income adults. As subsidies decline, insurance take- up falls rapidly, dropping about 25 percent for each $40 increase in monthly enrollee premiums. Marginal enrollees tend to be lower- cost, indicating adverse selection into insurance. Read More

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Effect of a Workplace Wellness Program on Employee Health and Economic Outcomes: A Randomized Clinical Trial.

JAMA 2019 04;321(15):1491-1501

University of Chicago Harris School of Public Policy, Chicago, Illinois.

Importance: Employers have increasingly invested in workplace wellness programs to improve employee health and decrease health care costs. However, there is little experimental evidence on the effects of these programs.

Objective: To evaluate a multicomponent workplace wellness program resembling programs offered by US employers. Read More

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http://dx.doi.org/10.1001/jama.2019.3307DOI Listing

[Research on patent quality of Chinese listed traditional Chinese medicine enterprises from R&D investment perspective].

Zhongguo Zhong Yao Za Zhi 2019 Mar;44(6):1284-1288

School of Management,Beijing University of Traditional Chinese Medicine Beijing 100029,China.

In recent years,the number of patent applications for traditional Chinese medicine( TCM) inventions has increased rapidly,but the authorization rate has declined. Listed TCM enterprises are a group of active innovators in this field,so this paper analyzes their patent quality by combining patent application and authorization with R&D investment of enterprises in order to explore a practical way to improve the quality of TCM patents. The conclusions are as follows: the R&D investment of listed TCM enterprises is insufficient and the gap between enterprises is large; the number of patent applications is within a reasonable range,but some enterprises still have abnormal patent applications,and patent quality needs to be improved; in addition,the patent operation capacity of enterprises still needs to be improved. Read More

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http://dx.doi.org/10.19540/j.cnki.cjcmm.2019.0024DOI Listing

How production-based and consumption-based emissions accounting systems change climate policy analysis: the case of CO convergence.

Environ Sci Pollut Res Int 2019 Apr 16. Epub 2019 Apr 16.

Department of Economics, Faculty of Economic and Administrative Sciences, Adnan Menderes University, Nazilli, Aydın, Turkey.

Much of the existing research analyses on emissions and climate policy are dominantly based on emissions data provided by production-based accounting (PBA) system. However, PBA provides an incomplete picture of driving forces behind these emission changes and impact of global trade on emissions, simply by neglecting the environmental impacts of consumption. To remedy this problem, several studies propose to consider national emissions calculated by consumption-based accounting (CBA) systems in greenhouse gas (GHG) assessments for progress and comparisons among the countries. Read More

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http://dx.doi.org/10.1007/s11356-019-05007-2DOI Listing

Disconnection description of triple-junction motion.

Proc Natl Acad Sci U S A 2019 Apr 15. Epub 2019 Apr 15.

Department of Materials Science and Engineering, University of Pennsylvania, Philadelphia, PA 19104-6272;

Grain boundary (GB) migration in polycrystalline materials necessarily implies the concurrent motion of triple junctions (TJs), the lines along which three GBs meet. Today, we understand that GB migration occurs through the motion of disconnections in the GB plane (line defects with both step and dislocation character). We present evidence from molecular dynamics grain growth simulations and idealized microstructures that demonstrates that TJ motion and GB migration are coupled through disconnection dynamics. Read More

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http://dx.doi.org/10.1073/pnas.1820789116DOI Listing

Gestational diabetes associated with incident diabetes in childhood and youth: a retrospective cohort study.

CMAJ 2019 Apr;191(15):E410-E417

Department of Medicine (Blotsky, Rahme, Dasgupta), McGill University; Centre for Outcomes Research and Evaluation (Blotsky, Rahme, Dahhou, Nakhla, Dasgupta), Research Institute of the McGill University Health Centre; Department of Pediatrics (Nakhla), Division of Endocrinology and Metabolism, McGill University, Montréal, Que.

Background: Indicators of childhood- and youth-onset diabetes may be useful for early detection of diabetes; there is a known association between composite exposure of parental type 2 diabetes and gestational diabetes mellitus with childhood- and youth-onset diabetes. We examined associations between gestational diabetes mellitus and incidence of childhood- and youth-onset diabetes in offspring.

Methods: Using public health insurance administrative databases from Quebec, Canada, we randomly selected singleton live births with maternal gestational diabetes mellitus (1990-2007) and matched them 1:1 with singleton live births without gestational diabetes mellitus. Read More

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http://www.cmaj.ca/lookup/doi/10.1503/cmaj.181001
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http://dx.doi.org/10.1503/cmaj.181001DOI Listing
April 2019
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Exploring the impacts of the 2012 Health and Social Care Act reforms to commissioning on clinical activity in the English NHS: a mixed methods study of cervical screening.

BMJ Open 2019 Apr 14;9(4):e024156. Epub 2019 Apr 14.

Division of Population Health, Health Services Research, and Primary Care, University of Manchester, Manchester, UK.

Objectives: Explore the impact of changes to commissioning introduced in England by the Health and Social Care Act 2012 (HSCA) on cervical screening activity in areas identified empirically as particularly affected organisationally by the reforms.

Methods: Qualitative followed by quantitative methods. Qualitative: semi-structured interviews (with NHS commissioners, managers, clinicians, senior administrative staff from Clinical Commissioning Groups (CCGs), local authorities, service providers), observations of commissioning meetings in two metropolitan areas of England. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-024156DOI Listing