28,495 results match your criteria Adjustment Disorders


The Effect of Pitch Auditory Feedback Perturbations on the Production of Anticipatory Phrasal Prominence and Boundary.

J Speech Lang Hear Res 2020 Jul 2:1-17. Epub 2020 Jul 2.

Roxelyn and Richard Pepper Department of Communication Sciences and Disorders, Northwestern University, Evanston, IL.

Purpose In this study, we investigated how the direction and timing of a perturbation in voice pitch auditory feedback during phrasal production modulated the magnitude and latency of the pitch-shift reflex as well as the scaling of acoustic production of anticipatory intonation targets for phrasal prominence and boundary. Method Brief pitch auditory feedback perturbations (±200 cents for 200-ms duration) were applied during the production of a target phrase on the first or the second word of the phrase. To replicate previous work, we first measured the magnitude and latency of the pitch-shift reflex as a function of the direction and timing of the perturbation within the phrase. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1044/2020_JSLHR-19-00043DOI Listing

Evaluation of Motivation for the Treatment of Drug Addicts with Personality Disorders.

Span J Psychol 2020 Jun 16;23:e15. Epub 2020 Jun 16.

Monash University (Australia).

Lack of motivation for the treatment of drug addiction is associated with dropout and relapses. Further, personality disorders (PD) have traditionally been linked to low motivation and therapeutic failure. Thus, the present study aims to analyze the structure of the Motivation for Treatment Questionnaire (MTQ-8), as well as to determine differences in motivation due to the presence of PD and the impact of psychological adjustment on motivation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/SJP.2020.13DOI Listing

Relationship Between Illness Representations, Psychosocial Adjustment, and Treatment Outcomes in Mental Disorders: A Mini Review.

Front Psychol 2020 12;11:1167. Epub 2020 Jun 12.

Aix Marseille Univ, LPS, Aix-en-Provence, France.

Understanding and improving the psychosocial adjustments (e.g., quality of life, depression) and treatment outcomes (e. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fpsyg.2020.01167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309516PMC

Increased Serum Calcium Level Promotes the Risk of Lymph Node Metastasis in Endometrial Cancer.

Cancer Manag Res 2020 25;12:5023-5030. Epub 2020 Jun 25.

Department of Obstetrics and Gynecology, Peking University People's Hospital, Beijing 100044, People's Republic of China.

Purpose: The early predictive values of diagnostic markers for lymph node metastasis (LNM) in endometrial cancer (EC) are still unclear at present. The purpose of this study is to explore the relationship between serum calcium and LNM in EC.

Methods: We identified all patients with EC who underwent surgery between January 2012 and December 2016. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2147/CMAR.S253914DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323808PMC

Trauma and violent offending among adolescents: a birth cohort study.

J Epidemiol Community Health 2020 Jul 1. Epub 2020 Jul 1.

Population Research Unit, Faculty of Social Science, University of Helsinki, Helsinki, Finland.

Background: Earlier studies, based on data collected among juvenile court clients or prisoners, suggest that there is an association between trauma and adolescent-onset offending. However, there is a lack of large-scale data on juvenile violence and clinical mental health observations with unselected participants, and a risk-factor-oriented research combining multiple variables affecting violent behaviour.

Methods: We analyse the effect of trauma on violent offending using longitudinal register-linkage population data. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/jech-2020-214188DOI Listing

The effects of transitions in metabolic health and obesity status on incident cardiovascular disease: Insights from a general Chinese population.

Eur J Prev Cardiol 2020 Jul 1:2047487320935550. Epub 2020 Jul 1.

Department of Cardiology, The First Hospital of China Medical University, China.

Background: Recent studies have investigated the association of transitions in metabolic health and obesity status over time with the risk of cardiovascular disease, focusing on the subgroup demonstrating metabolically healthy obesity. However, these studies have produced inconsistent results. This study evaluates the relation in a general Chinese population. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/2047487320935550DOI Listing

Maternal Common Mental Disorders symptoms influence associated with early childhood dental caries: A cross-sectional study in a southern Brazilian city.

Int J Paediatr Dent 2020 Jun 30. Epub 2020 Jun 30.

Professor at Graduate Program in Dentistry, FederalUniversity of Pelotas, 457, Gonçalves Chaves St. Pelotas, Pelotas, Brazil.

Background: Maternal mental problems can interfere with the overall health and care of the child, some oral health studies have been trying to elucidate if there is a relationship between maternal common mental disorders (CMD) and children's oral health status.

Aim: The aim was to investigate the influence of mothers that present CMD symptoms on their child's dental caries status.

Design: This cross-sectional study was carried out in Pelotas with 530 mother/child (aged 2-5 years old) dyads recruited from an epidemiological survey in August, 2015 during the national vaccination campaign. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ipd.12685DOI Listing

Comparison of prevalence and associated factors of depressive disorder between patients with head and neck cancer and those with lung cancer at a tertiary hospital in Taiwan: a cross-sectional study.

BMJ Open 2020 Jun 29;10(6):e037918. Epub 2020 Jun 29.

Department of Child and Adolescent Psychiatry, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan

Objective: Depression is a common comorbidity in cancer patients. This study aimed to compare the prevalence and associated factors of depressive disorder between patients with head and neck cancer (HNC) and those with lung cancer (LC).

Design: This study used a cross-sectional design with consecutive sampling. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bmjopen-2020-037918DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328812PMC

Alzheimer's Disease and Related Disorders Prevalence Differs by Appalachian Residence in Ohio.

J Alzheimers Dis 2020 Jun 22. Epub 2020 Jun 22.

Neurological Institute, College of Medicine, The Ohio State University, Columbus, OH, USA.

Background: Areas within the Appalachian region may have a greater burden of under diagnosed Alzheimer's disease and related disorders (ADRD).

Objective: To estimate the prevalence of ADRD in the Appalachian counties of Ohio, and to determine if differences exist by geographic location (Appalachian/non-Appalachian and rural/urban) and across time among Medicare beneficiaries.

Methods: Centers for Medicare and Medicaid Services Public Use Files from 2007-2017 were used to estimate county-level ADRD prevalence among all fee-for-service beneficiaries in Ohio. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3233/JAD-200491DOI Listing

Onset and Severity of Early Disruptive Behavioral Disorders in Treatment-Seeking Substance Use Disorder Patients with and without Attention-Deficit/Hyperactivity Disorder.

Eur Addict Res 2020 Jun 26:1-12. Epub 2020 Jun 26.

Radboudumc, Donders Centre for Medical Neuroscience, Department of Psychiatry, Nijmegen, The Netherlands.

Aims: This study addressed the age of onset of conduct disorder (CD) and oppositional defiant disorder (ODD) in treatment-seeking substance use disorder (SUD) patients with and without adult attention-deficit/hyperactivity disorder (ADHD) and its association with early onset of SUD.

Methods: We examined data from the 2nd International ADHD in Substance Use Disorders Prevalence Study, including 400 adults in SUD treatment from Puerto Rico, Hungary, and Australia. ADHD, SUD, and CD/ODD were assessed with the Conners Adult ADHD Diagnostic Interview for DSM-IV, the MINI International Neuropsychiatric Interview, and the K-SADS, respectively. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000508653DOI Listing

Prevalence of cervical anterior and posterior spondylolisthesis and its association with degenerative cervical myelopathy in a general population.

Sci Rep 2020 Jun 26;10(1):10455. Epub 2020 Jun 26.

Department of Orthopaedic Surgery, Wakayama Medical University, 811-1 Kimiidera, Wakayama City, Wakayama, Japan.

The purpose of this study was to examine the prevalence of cervical spondylolisthesis according to age and vertebral level and its association with degenerative cervical myelopathy (DCM). This study included 959 participants (319 men and 640 women; mean age, 66.4 years) in the Wakayama Spine Study from 2008 to 2010. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-020-67239-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320182PMC

Triglyceride Glucose Index and Prognosis of Patients With Ischemic Stroke.

Front Neurol 2020 10;11:456. Epub 2020 Jun 10.

Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.

The triglyceride glucose index (TyG index) has been proposed as a simple and credible surrogate marker of insulin resistance. However, it is unclear whether TyG index correlates with adverse clinical outcomes in patients with ischemic stroke. Accordingly, this study aimed to explore the relationship between baseline TyG index and clinical outcomes of ischemic stroke individuals. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fneur.2020.00456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297915PMC

Continuity of health anxiety from childhood to adolescence and associated healthcare costs: a prospective population-based cohort study.

J Child Psychol Psychiatry 2020 Jun 25. Epub 2020 Jun 25.

Department of Child and Adolescent Psychiatry, Research Unit, Aarhus University Hospital, Aarhus, Denmark.

Background: Severe health anxiety (HA) is characterized by excessive and impairing worry and preoccupation with health issues and can cause increased and unnecessary medical examinations. HA in childhood and adolescence is scarcely explored, hindering the potential for prevention and early intervention.

Methods: HA was assessed in 1,278 children/youths at two time points at ages 11 and 16 years in a general population-based birth cohort. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jcpp.13286DOI Listing

Prevalence and risk factors of postpartum depression and adjustment disorder during puerperium - a retrospective research.

J Reprod Infant Psychol 2020 Jun 25:1-13. Epub 2020 Jun 25.

Mental Health Service of Camposampiero General Hospital, ULSS6 Euganea - "Mothers without Depression" , Padua, Italy.

Objective: This observational study was designed to evaluate risk factors and distribution of Adjustment Disorder (AD) and Postnatal Depression (PPD), after delivery and a positive screening at Camposampiero Hospital (2012-2017).

Background: After childbirth, women are vulnerable to develop psychological disorders. Since the effects of psychopathology are relevant, prevention and early intervention are of paramount importance. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/02646838.2020.1786035DOI Listing

Exacerbation of Hyperparathyroidism, Secondary to a Reduction in Kidney Function, in Individuals With Vitamin D Deficiency.

Front Med (Lausanne) 2020 5;7:221. Epub 2020 Jun 5.

Department of Social Medicine, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.

Chronic kidney disease (CKD)-mineral and bone disorders (CKD-MBD) are an adverse outcome derived from decreases in kidney function, where abnormality of serum concentrations of calcium (Ca), phosphorus, parathyroid hormone (PTH), and vitamin D can be seen simultaneously. To identify individuals at risk for CKD-MBD or secondary hyperparathyroidism, the relationships between estimated glomerular filtration rate (eGFR) and serum PTH concentration were evaluated, allowing for confounding factors, in particular vitamin D status, in a general Japanese population. Nine-hundred-and-thirty participants in the population-based Iwaki study conducted in 2016 who were not on drugs affecting mineral metabolism nor hemodialysis, were included in the study (326 men and 604 women; age: 55. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fmed.2020.00221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289923PMC

Increased body mass index percentile is associated with decreased epiphyseal tubercle size in asymptomatic children and adolescents with healthy hips.

J Child Orthop 2020 Jun;14(3):167-174

Department of Orthopaedic Surgery, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Purpose: To investigate whether body mass index (BMI) percentile impacts the morphology of the capital femoral epiphysis in children and adolescents without hip disorders.

Methods: We assessed 68 subjects with healthy hips who underwent a pelvic CT for evaluation of appendicitis. There were 32 male patients (47%) and the mean age was 11. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1302/1863-2548.14.200042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302419PMC

Drug use by men admitted to a psychiatric hospital.

Rev Lat Am Enfermagem 2020 19;28:e3296. Epub 2020 Jun 19.

Universidade Estadual de Maringá, Maringá, PR, Brazil.

Objective: to assess risk related to drug use in men admitted to a psychiatric hospital and to identify associations with sociodemographic, socioeconomic variables, and risk conditions.

Method: a cross-sectional study with the application of a screening test in 209 participants hospitalized for mental and behavioral disorders due to the use of psychoactive substances. Statistical analysis was performed using descriptive statistics and adjustment of a binary logistic regression model for moderate or high risk of drug use. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1590/1518-8345.3370.3296DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304981PMC

Impact of Cognitive Frailty on Activities of Daily Living, Cognitive Function, and Conversion to Dementia Among Memory Clinic Patients with Mild Cognitive Impairment.

J Alzheimers Dis 2020 Jun 17. Epub 2020 Jun 17.

Center for Comprehensive Care and Research on Memory Disorders, National Center for Geriatrics and Gerontology, Obu, Japan.

Background: Very few studies have investigated the impact of cognitive frailty in clinical settings, especially in memory clinic populations.

Objective: To examine the impact of cognitive frailty on activities of daily living (ADL), cognitive function, and conversion to dementia among memory clinic patients with mild cognitive impairment (MCI).

Methods: The subjects of this retrospective study were 248 MCI patients (mean age, 76. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3233/JAD-191135DOI Listing

Life stressors, hypertensive disorders of pregnancy, and preterm birth.

J Psychosom Obstet Gynaecol 2020 Jun 22:1-9. Epub 2020 Jun 22.

Division of Public Health, University of Utah, Salt Lake City, UT, USA.

Stress-induced pregnancy complications are thought to represent a significant cause of maternal morbidity and mortality; little is known regarding types of stress most predictive of adverse outcomes. We used Utah PRAMs 2012-2014 data to evaluate links between preconception life stressors and prevalence of hypertensive disorders of pregnancy (HDP) and pre-term labor (PTB) (births <37 weeks gestational age, and very PTB <33 weeks). We categorized 12 specific stressful events into 4 groups: partner, traumatic, financial, and emotional. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/0167482X.2020.1778666DOI Listing

Mapping the Relationship between Dysmorphology and Cognitive, Behavioral, and Developmental Outcomes in Children with Autism Spectrum Disorder.

Autism Res 2020 Jun 22. Epub 2020 Jun 22.

National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

Previous studies investigating the association between dysmorphology and cognitive, behavioral, and developmental outcomes among individuals with autism spectrum disorder (ASD) have been limited by the binary classification of dysmorphology and lack of comparison groups. We assessed the association using a continuous measure of dysmorphology severity (DS) in preschool children aged 2-5 years (322 with ASD and intellectual disability [ID], 188 with ASD without ID, and 371 without ASD from the general population [POP]). In bivariate analyses, an inverse association between DS and expressive language, receptive language, fine motor, and visual reception skills was observed in children with ASD and ID. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/aur.2314DOI Listing

Cumulative incidence and relative risk of sleep problems among children and adolescents with newly diagnosed neurodevelopmental disorders: A nationwide register-based study.

J Sleep Res 2020 Jun 21:e13122. Epub 2020 Jun 21.

National Centre for Register-Based Research, Aarhus University, Aarhus, Denmark.

We estimated the absolute and relative risk of sleep problems in children and adolescents with newly diagnosed neurodevelopmental disorders. This was a population-based cohort study of individuals born in Denmark in 1993-2014 and followed in nationwide registers in 2011-2016. We estimated the 5-year cumulative incidence of sleep problems in incident cases of attention-deficit/hyperactivity disorder (ADHD; n = 12,844), autism spectrum disorder (ASD; n = 8,073), oppositional defiant disorder/conduct disorder (ODD/CD; n = 2,234) and epilepsy (n = 3,709). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jsr.13122DOI Listing

Understanding help-seeking behaviour in relation to psychosocial support services among Japanese cancer patients.

Jpn J Clin Oncol 2020 Jun 22. Epub 2020 Jun 22.

Graduate School of Human Sciences, Osaka University, Osaka, Japan.

Background: There are various psychosocial support services for cancer patients in Japan; however, their utilization rate is lower than in Western countries. The aim of this study was to investigate the actual status of the utilization of such services and the related factors of their use, using the transtheoretical model.

Methods: We conducted an Internet survey of cancer outpatients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jjco/hyaa086DOI Listing

Associations between growing up in natural environments and subsequent psychiatric disorders in Denmark.

Environ Res 2020 Jun 11;188:109788. Epub 2020 Jun 11.

Centre for Integrated Register-based Research (CIRRAU), Aarhus University, 8210, Aarhus V, Denmark; Big Data Centre for Environment and Health (BERTHA), Aarhus University, 8210, Aarhus V, Denmark; National Centre for Register-based Research, Aarhus BSS, Department of Economics and Business Economics, Aarhus University, 8210, Aarhus V, Denmark; The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Aarhus University, 8210, Aarhus V, Denmark. Electronic address:

Natural environments have been associated with mental health benefits worldwide. However, how different elements and types of natural environments associate with mental health is still largely unknown. In this study, we perform a detailed analysis on a large, nation-wide data set of mental health records (908 553 individuals) for Denmark combined with remotely-sensed land cover and vegetation density data. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.envres.2020.109788DOI Listing

Life negative events and depressive symptoms: the China longitudinal ageing social survey.

BMC Public Health 2020 Jun 19;20(1):968. Epub 2020 Jun 19.

School of Computational Science and Engineering, Georgia Institute of Technology, 756 W Peachtree St NW, Atlanta, 30308, Georgia, USA.

Background: Although some studies have reported the association between life negative events and depressive disorders, very limited studies have examined the association between life negative events exposure and depressive symptoms risk among Chinese older adults.

Methods: Data were obtained from the China Longitudinal Ageing Social Survey (CLASS), which was a stratified, multi-stage, probabilistic sampling survey, conducted in 2014. General linear regression and logistic regression were used to examine the association between life negative events exposure and depressive symptoms among Chinese older adults. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12889-020-09119-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305594PMC

The effect of tactile feedback on gait initiation in people with Parkinson's disease: A pilot study.

Gait Posture 2020 Jun 3;80:240-245. Epub 2020 Jun 3.

Balance Disorders Laboratory, Oregon Health & Science University, Portland, OR, USA. Electronic address:

Background: Gait initiation and turning are common triggers for Freezing of Gait (FOG) in people with Parkinson's disease (PD). Recently, it has been shown that closed-loop tactile feedback (CLTF) can be effective to improve turning performance in people with FOG.

Research Question: Does CLTF change the preparation and execution of the first step during gait initiation?

Methods: People (n = 36) with PD with FOG (PD + FOG) (n = 18) and without FOG (PD-FOG) (n = 18) were included in the study and performed self-initiated gait with or without CLTF under single and dual task conditions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.gaitpost.2020.06.001DOI Listing

A Randomized, Controlled Trial of Exercise for Parkinsonian Individuals With Freezing of Gait.

Mov Disord 2020 Jun 18. Epub 2020 Jun 18.

Laboratory of Strength Training, School of Physical Education and Sport, University of São Paulo, São Paulo, SP, Brazil.

Background: Exercises with motor complexity induce neuroplasticity in individuals with Parkinson's disease (PD), but its effects on freezing of gait are unknown. The objective of this study was to verify if adapted resistance training with instability - exercises with motor complexity will be more effective than traditional motor rehabilitation - exercises without motor complexity in improving freezing-of-gait severity, outcomes linked to freezing of gait, and brain function.

Methods: Freezers were randomized either to the adapted resistance training with instability group (n = 17) or to the active control group (traditional motor rehabilitation, n = 15). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mds.28128DOI Listing

Chemerin concentrations in infants born small for gestational age: correlations with triglycerides and parameters related to glucose homeostasis.

J Physiol Biochem 2020 Jun 16. Epub 2020 Jun 16.

Nutrition and Obesity Group, Department of Nutrition and Food Science, University of the Basque Country (UPV/EHU) and Lucio Lascaray Research Institute, 01006, Vitoria, Spain.

Infants born small for gestational age (SGA) are known to have increased risk of developing several pathologies, including the metabolic syndrome, when they grow up. It has been described that both the growth pattern of these children as well as the risk of their presenting future metabolic disorders can be influenced by the expression of adipokines. Among them, chemerin has demonstrated to be implicated in lipid and glucose metabolism, presenting higher circulating concentration in diabetic and obese subjects. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s13105-020-00750-4DOI Listing

Comorbidity is associated with disease activity in MS: Findings from the CombiRx trial.

Neurology 2020 Jun 17. Epub 2020 Jun 17.

Departments of Internal Medicine and Community Health Sciences, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, CAN.

Objective: To determine whether comorbidity is associated with clinical (relapses, disability worsening) and MRI outcomes in multiple sclerosis (MS), we conducted a secondary analysis of the CombiRx clinical trial.

Methods: CombiRx compared interferon-beta-1a, glatiramer acetate and the combination of these agents. For participants eligible for evaluation of 6-month confirmed disability worsening, we used medical history, concomitant medications and adverse events to ascertain comorbidity status. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/WNL.0000000000010024DOI Listing

Intravenous thrombolysis in patients with chronic kidney disease: A systematic review and meta-analysis.

Neurology 2020 Jun 17. Epub 2020 Jun 17.

From the Department of Neurology (K.M., A.T.), Allegheny Health Network, Pittsburgh, PA; Department of Neurology (A.H.K., A.W.A., A.V.A.), University of Ioannina School of Medicine, Greece; Department of Neurology (N.G., G.T.), University of Tennessee Health Science Center, Memphis; Department of Neurology and Stroke Center (H.G., G.M.D.M.), University Hospital Basel and University of Basel, Switzerland; Department of Neurology (P.D.M.), School of Medicine, University of Crete, Greece; Department of Cardiology (E.B.), Oslo University Hospital, Norway; and Second Department of Neurology (G.T.), National & Kapodistrian University of Athens, "Attikon" University Hospital, Greece.

Objective: To determine the association of chronic kidney disease (CKD) with the safety and efficacy of IV thrombolysis (IVT) among patients with acute ischemic stroke (AIS).

Methods: A systematic review and pairwise meta-analysis of studies involving patients with CKD undergoing IVT for AIS were conducted to evaluate the following outcomes: symptomatic intracranial hemorrhage (sICH), asymptomatic and any intracranial hemorrhage (ICH), in-hospital and 3-month mortality, 3-month favorable functional outcome (FFO; modified Rankin Scale [mRS] score 0-1), and 3-month functional independence (FI, mRS score 0-2). CKD was defined with estimated glomerular filtration rate (eGFR) ranging from mild (eGFR 60-89 mL/min) to moderate (eGFR 30-59 mL/min) to severe (eGFR 15-29 mL/min). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/WNL.0000000000009756DOI Listing

Adjustment and coronavirus: How to prepare for COVID-19 pandemic-related adjustment disorder worldwide?

Psychol Trauma 2020 Jun 18. Epub 2020 Jun 18.

Department of Basic, Clinical Psychology and Psychobiology, Jaume I University.

As the 2019 novel coronavirus (COVID-19) is spreading worldwide in 2020, there is a growing concern about the impact of the pandemic on mental health. Multiple stressors associated with the pandemic, such as health-related stressors, job loss, and work-related stressors, could increase the prevalence of adjustment disorders worldwide. The present article acknowledges adjustment disorder as a highly relevant mental health outcome of the pandemic that should be addressed by mental health professionals. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1037/tra0000706DOI Listing

Association between yogurt consumption and plasma soluble CD14 in two prospective cohorts of US adults.

Eur J Nutr 2020 Jun 16. Epub 2020 Jun 16.

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

Purpose: Although evidence suggests an inverse association between yogurt consumption and the risk of disorders, such as type 2 diabetes and certain cancers, the mechanisms remain poorly understood. We aimed to examine the association between yogurt consumption and concentrations of plasma soluble CD14, a marker of gut barrier dysfunction.

Methods: We analyzed cross-sectional data from 632 women in the Nurses' Health Study (1989-1990) and 444 men in the Health Professionals Follow-up Study (1993-1994) with soluble CD14 concentrations. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00394-020-02303-3DOI Listing

Associations of iron status with apolipoproteins and lipid ratios: a cross-sectional study from the China Health and Nutrition Survey.

Lipids Health Dis 2020 Jun 16;19(1):140. Epub 2020 Jun 16.

Department of Endocrinology and Metabolism, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China.

Background: Iron overload has been found to be related with various cardiometabolic disorders, like dyslipidemia, metabolic syndrome, and diabetes. The disturbance of the iron status and lipid metabolism can contribute to organ damage such as atherosclerotic plaque growth and instability. An assessment on the associations of iron status with apolipoproteins and lipid ratios would be informative for maintenance of metabolic homeostasis and hinderance of disease progression. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12944-020-01312-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298938PMC

History of Serious Mental Illness is a Predictor of Morbidity and Mortality in Cardiac Surgery.

Ann Thorac Surg 2020 Jun 13. Epub 2020 Jun 13.

Division of Thoracic and Cardiovascular Surgery, University of Virginia, Charlottesville, VA. Electronic address:

Background: Serious Mental Illness (SMI), defined as a mental disorder causing functional impairment, affects 9.8 million Americans. SMI correlates with earlier onset, more extensive cardiac disease, and reduced life expectancy by 25 years. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.athoracsur.2020.04.118DOI Listing

Postoperative Psychological Disorders Among Heart Transplant Recipients: A Meta-Analysis and Meta-regression.

Psychosom Med 2020 Jun 12. Epub 2020 Jun 12.

Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.

Objectives: This meta-analysis evaluates the pooled prevalence of depression, anxiety, adjustment disorder and Post-Traumatic Stress Disorder (PTSD) among heart transplant recipients globally and determines underlying moderators.

Methods: The authors searched PubMed, Embase, PsychINFO, BIOSIS, Science Direct and Cochrane CENTRAL databases from inception to 1 March 2019; and 1321 records, and 42 full-text articles were selected and reviewed according to PRISMA guidelines. We calculated the pooled prevalence proportion of depression, anxiety, adjustment disorder and PTSD using random effects models. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PSY.0000000000000833DOI Listing

Genetic factors underlying the bidirectional relationship between autoimmune and mental disorders - findings from a Danish population-based study.

Brain Behav Immun 2020 Jun 10. Epub 2020 Jun 10.

CORE-Copenhagen Research Centre for Mental Health, Mental Health Centre Copenhagen, Copenhagen University Hospital, Copenhagen, Denmark; Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. Electronic address:

Background: Previous studies have indicated the bidirectionality between autoimmune and mental disorders. However, genetic studies underpinning the co-occurrence of the two disorders have been lacking. In this study, we examined the potential genetic contribution to the association between autoimmune and mental disorders and investigated the genetic basis of overall autoimmune disease. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbi.2020.06.014DOI Listing

The earlier the better or the later the better: optimal timing of fetal reduction from twins to singleton.

Ultrasound Obstet Gynecol 2020 Jun 12. Epub 2020 Jun 12.

Department of Obstetrics and Gynecology, Sheba Medical Center, Tel-Hashomer, Israel.

Objectives: The aim of this study was to compare pregnancy complications, obstetric and neonatal outcomes of twin pregnancies that were reduced to singletons at early versus later gestational age.

Methods: From January 2005 through February 2017, 248 dichorionic diamniotic twin pregnancies underwent reduction to singleton in a single tertiary referral center. Fetal reductions performed at 11-14 weeks' gestation were mainly done at the patient's request or as a result of a complicated medical or obstetric history (early reduction, n=172). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/uog.22119DOI Listing

Elucidating Predictors of Obesity Hypoventilation Syndrome in a Large Bariatric Surgery Cohort.

Ann Am Thorac Soc 2020 Jun 11. Epub 2020 Jun 11.

Case Western Reserve University, Sleep Center, Neurologic Institute, Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio, United States;

Rationale: Although understanding predictors of obesity hypoventilation syndrome (OHS), a condition associated with increased morbidity and mortality, is of key importance for risk prediction, existing characterization is limited.

Objectives: We hypothesize that OHS patients referred for bariatric surgery have more severe obstructive sleep apnea (OSA) and metabolic derangements compared to their eucapnic counterparts.

Methods: 1718 patients undergoing polysomnography (PSG) with end-tidal CO2 monitoring prior to bariatric surgery at Cleveland Clinic from September 2011 to September 2018 were included. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1513/AnnalsATS.202002-135OCDOI Listing

Association of Benzodiazepines and Antidepressants With 180-Day Mortality Among Patients With Dementia Receiving Antipsychotic Pharmacotherapy: A Nationwide Registry-Based Study.

J Clin Psychiatry 2020 Jun 2;81(4). Epub 2020 Jun 2.

Danish Dementia Research Centre, Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

Objective: Antipsychotic drugs are known to increase mortality among patients with dementia. Many patients receive concomitant treatment with other psychotropic agents. The aim of this retrospective cohort study was to investigate the impact of benzodiazepines and antidepressants on the risk of death in patients with dementia initiating antipsychotic drug treatment. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4088/JCP.19m12828DOI Listing

A Report of the Telepsychiatric Evaluation of SARS-CoV-2 Patients.

Telemed J E Health 2020 Jun 11. Epub 2020 Jun 11.

Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran.

     Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/tmj.2020.0125DOI Listing

Alcohol Use Disorders Are Associated With a Unique Impact on Airway Epithelial Cell Gene Expression.

Alcohol Clin Exp Res 2020 Jun 11. Epub 2020 Jun 11.

Division of Pulmonary Sciences and Critical Care Medicine (MY, IVY, ELB), Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado.

Background: Alcohol use disorders (AUDs) and cigarette smoking both increase risk for the development of community-acquired pneumonia (CAP), likely through adverse effects on proximal airway mucociliary clearance and pathogen recognition. Smoking-related alterations on airway gene expression are well described, but little is known about the impact of AUDs. We measured gene expression in human airway epithelial cells (AECs), hypothesizing that AUDs would be associated with novel differences in gene expression that could alter risk for CAP. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/acer.14395DOI Listing

Phase I study of vemurafenib in children with recurrent or progressive BRAF mutant brain tumors: Pacific Pediatric Neuro-Oncology Consortium study (PNOC-002).

Oncotarget 2020 May 26;11(21):1942-1952. Epub 2020 May 26.

Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.

BRAF mutation is present in a subset of pediatric brain tumors. Vemurafenib is an oral, selective ATP-competitive inhibitor of BRAF kinase. The goal of this multi-center study conducted through the Pacific Pediatric Neuro-Oncology Consortium (PNOC) was to determine the recommended phase 2 dose (RP2D) and dose limiting toxicities (DLTs) in children < 18 years with recurrent or progressive BRAF mutant brain tumors. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.27600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260122PMC

Sex-specific relationship between vascular calcification and incident fracture in patients with end-stage renal disease.

Kidney Res Clin Pract 2020 Jun 10. Epub 2020 Jun 10.

Division of Nephrology, Department of Internal Medicine, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Republic of Korea.

Background: Vascular calcification (VC) is a major component of mineral bone disorders in patients with endstage renal disease (ESRD). Bone metabolism is affected by various factors, including sex hormones. This study investigated whether there was a sex-specific relationship between VC and incident fracture in patients with ESRD. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.23876/j.krcp.20.013DOI Listing

The potential risk factors of nephrotoxicity during vancomycin therapy in Chinese adult patients.

Eur J Hosp Pharm 2020 Jun 10. Epub 2020 Jun 10.

Department of Pharmacy, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.

Objective: To evaluate potential risk factors that may make patients susceptible to nephrotoxicity in those concomitantly receiving vancomycin in the hospital.

Methods: This was a single-centre retrospective analysis of patients treated with vancomycin for gram-positive or mixed infections in the Renmin Hospital of Wuhan University from January 2017 to May 2018. All of them were treated for ≥48 hours and had no kidney disease. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/ejhpharm-2020-002261DOI Listing

Harmonizing light transmission aggregometry in the Netherlands by implementation of the SSC-ISTH guideline.

Platelets 2020 Jun 11:1-8. Epub 2020 Jun 11.

Central Diagnostic Laboratory, Maastricht University Medical Centre + , Maastricht, The Netherlands.

Light transmission aggregometry (LTA) is considered the gold standard method for evaluation of platelet function. However, there are a lot of variation in protocols (pre-analytical procedures and agonist concentrations) and results. The aim of our study was to establish a national LTA protocol, to investigate the effect of standardization and to define national reference values for LTA. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/09537104.2020.1771549DOI Listing

Higher cortisol levels may proceed a manic episode and are related to disease severity in patients with bipolar disorder.

Psychoneuroendocrinology 2020 Apr 28;119:104658. Epub 2020 Apr 28.

Department of Mood Disorders, Parnassia NAH, Rotterdam, The Netherlands.

Background: Regulation of the hypothalamic-pituitary-adrenal (HPA) axis is implicated in the pathogenesis of bipolar disorder (BD). However, the relationship between HPA-activity and disease severity is not fully elucidated. In this pilot study we aimed to explore the temporal relationship between HPA-activity and the risk of a manic episode in BD patients type I, by assessing long-term hair cortisol concentrations (HCC). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.psyneuen.2020.104658DOI Listing

Purpose in life in adulthood and older adulthood: integrative review.

Cien Saude Colet 2020 Jun 13;25(6):2127-2142. Epub 2018 Oct 13.

Faculdade de Ciências Médicas, Universidade Estadual de Campinas. Cidade Universitária Zeferino Vaz, Barão Geraldo. 13083-970, Campinas, SP, Brasil.

Purpose in life (PiL) is defined as the sense that life has meaning and intentionality, and plays a guiding role in life goals and decision making regarding the use of personal resources.

Objectives: to recognize and analyze data on PiL and conditions associated with good aging or with positive adaptation in aging.

Method: an integrative review of articles in peer-reviewed journals published in the PubMed/Medline, Scopus, Web of Science, PsycInfo and Scielo/BVS/Lilacs databases was performed using the terms "purpose in life" and "aging" in the title, without temporal restriction. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1590/1413-81232020256.20602018DOI Listing

Occlusion and Temporomandibular Disorders: A Long-Standing Controversy in Dentistry.

Authors:
Ziad Al-Ani

Prim Dent J 2020 Mar;9(1):43-48

Senior Lecturer, Glasgow Dental Hospital and School.

The relationship between temporomandibular disorders (TMDs) and occlusion remains controversial. Some authors believe that occlusion is the primary factor in the onset of TMD symptoms, whereas others feel that occlusion has no role in this at all. The majority of reasoning behind causation is based upon anecdotal rather than scientific evidence. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/2050168420911029DOI Listing

Gut microbiome composition and risk factors in a large cross-sectional IBS cohort.

BMJ Open Gastroenterol 2020 6;7(1):e000345. Epub 2020 Apr 6.

Medical Affairs, uBiome, San Francisco, California, USA.

Objective: Irritable bowel syndrome (IBS) is a common gastrointestinal disorder that is difficult to diagnose and treat due to its inherent heterogeneity and unclear aetiology. Although there is evidence suggesting the importance of the microbiome in IBS, this association remains poorly defined. In the current study, we aimed to characterise a large cross-sectional cohort of patients with self-reported IBS in terms of microbiome composition, demographics, and risk factors. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bmjgast-2019-000345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254124PMC